Carboxy-Lyases

"Carboxy-Lyases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze the addition of a carboxyl group to a compound (carboxylases) or the removal of a carboxyl group from a compound (decarboxylases). EC 4.1.1.

Descriptor ID

D002262

MeSH Number(s)

D08.811.520.224.125

Concept/Terms

Carboxy-Lyases

Below are MeSH descriptors whose meaning is more general than "Carboxy-Lyases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Lyases [D08.811.520]
Carbon-Carbon Lyases [D08.811.520.224]
Carboxy-Lyases [D08.811.520.224.125]

Below are MeSH descriptors whose meaning is related to "Carboxy-Lyases".

Below are MeSH descriptors whose meaning is more specific than "Carboxy-Lyases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carboxy-Lyases" by people in Harvard Catalyst Profiles by year, and whether "Carboxy-Lyases" was a major or minor topic of these publication.

Bar chart showing 44 publications over 21 distinct years, with a maximum of 4 publications in 2011 and 2019 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1995	1	1	2
1998	1	0	1
1999	1	0	1
2000	0	1	1
2001	3	0	3
2006	1	0	1
2008	2	0	2
2009	3	0	3
2010	3	0	3
2011	3	1	4
2012	1	0	1
2013	2	0	2
2014	1	0	1
2015	3	0	3
2017	0	3	3
2018	1	1	2
2019	1	3	4
2020	1	0	1
2021	4	0	4
2022	0	1	1

Below are the most recent publications written about "Carboxy-Lyases" by people in Profiles.

Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection. PLoS Pathog. 2022 01; 18(1):e1010219.

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Safety of AADC Gene Therapy for Moderately Advanced Parkinson Disease: Three-Year Outcomes From the PD-1101 Trial. Neurology. 2022 01 04; 98(1):e40-e50.

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Gene therapy in the putamen for curing AADC deficiency and Parkinson's disease. EMBO Mol Med. 2021 09 07; 13(9):e14712.

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Targeting leukemia-specific dependence on the de novo purine synthesis pathway. Leukemia. 2022 02; 36(2):383-393.

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Conditional targeting of phosphatidylserine decarboxylase to lipid droplets. Biol Open. 2021 03 03; 10(3).

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Considerations of expanded carrier screening: Lessons learned from combined malonic and methylmalonic aciduria. Mol Genet Genomic Med. 2021 04; 9(4):e1621.

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Pyrazinamide triggers degradation of its target aspartate decarboxylase. Nat Commun. 2020 04 03; 11(1):1661.

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Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv. 2019 09; 5(9):eaax8352.

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The l-Thr Kinase/l-Thr-Phosphate Decarboxylase (CobD) Enzyme from Methanosarcina mazei Gö1 Contains Metallocenters Needed for Optimal Activity. Biochemistry. 2019 07 30; 58(30):3260-3279.

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The Liberfarb syndrome, a multisystem disorder affecting eye, ear, bone, and brain development, is caused by a founder pathogenic variant in thePISD gene. Genet Med. 2019 12; 21(12):2734-2743.

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