Sodium-Phosphate Cotransporter Proteins, Type IIa
"Sodium-Phosphate Cotransporter Proteins, Type IIa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An electrogenic sodium-dependent phosphate transporter. It is present primarily in BRUSH BORDER membranes of PROXIMAL RENAL TUBULES.
MeSH Number(s)
D12.776.157.530.450.074.750.750.750.124
D12.776.157.530.450.625.625.750.124
D12.776.157.648.500.750.750.124
D12.776.543.585.450.074.750.750.750.124
D12.776.543.585.450.625.625.750.124
Concept/Terms
Sodium-Phosphate Cotransporter Proteins, Type IIa- Sodium-Phosphate Cotransporter Proteins, Type IIa
- Sodium Phosphate Cotransporter Proteins, Type IIa
- Type IIa Sodium-Phosphate Cotransporter Proteins
- Type IIa Sodium Phosphate Cotransporter Proteins
- Type IIa Sodium-Phosphate Symporter Proteins
- Type IIa Sodium Phosphate Symporter Proteins
- NPTIIa Transporter Proteins
- Transporter Proteins, NPTIIa
Below are MeSH descriptors whose meaning is more general than "Sodium-Phosphate Cotransporter Proteins, Type IIa".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Pumps [D12.776.157.530.450]
- Anion Transport Proteins [D12.776.157.530.450.074]
- Phosphate Transport Proteins [D12.776.157.530.450.074.750]
- Sodium-Phosphate Cotransporter Proteins [D12.776.157.530.450.074.750.750]
- Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.530.450.074.750.750.750]
- Sodium-Phosphate Cotransporter Proteins, Type IIa [D12.776.157.530.450.074.750.750.750.124]
- Symporters [D12.776.157.530.450.625]
- Sodium-Phosphate Cotransporter Proteins [D12.776.157.530.450.625.625]
- Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.530.450.625.625.750]
- Sodium-Phosphate Cotransporter Proteins, Type IIa [D12.776.157.530.450.625.625.750.124]
- Phosphate-Binding Proteins [D12.776.157.648]
- Phosphate Transport Proteins [D12.776.157.648.500]
- Sodium-Phosphate Cotransporter Proteins [D12.776.157.648.500.750]
- Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.648.500.750.750]
- Sodium-Phosphate Cotransporter Proteins, Type IIa [D12.776.157.648.500.750.750.124]
- Membrane Proteins [D12.776.543]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Pumps [D12.776.543.585.450]
- Anion Transport Proteins [D12.776.543.585.450.074]
- Phosphate Transport Proteins [D12.776.543.585.450.074.750]
- Sodium-Phosphate Cotransporter Proteins [D12.776.543.585.450.074.750.750]
- Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.543.585.450.074.750.750.750]
- Sodium-Phosphate Cotransporter Proteins, Type IIa [D12.776.543.585.450.074.750.750.750.124]
- Symporters [D12.776.543.585.450.625]
- Sodium-Phosphate Cotransporter Proteins [D12.776.543.585.450.625.625]
- Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.543.585.450.625.625.750]
- Sodium-Phosphate Cotransporter Proteins, Type IIa [D12.776.543.585.450.625.625.750.124]
Below are MeSH descriptors whose meaning is more specific than "Sodium-Phosphate Cotransporter Proteins, Type IIa".
This graph shows the total number of publications written about "Sodium-Phosphate Cotransporter Proteins, Type IIa" by people in Harvard Catalyst Profiles by year, and whether "Sodium-Phosphate Cotransporter Proteins, Type IIa" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 3 | 3 |
2009 | 0 | 1 | 1 |
2010 | 2 | 2 | 4 |
2011 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2013 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2016 | 0 | 3 | 3 |
2017 | 1 | 0 | 1 |
2018 | 1 | 1 | 2 |
2019 | 1 | 1 | 2 |
2020 | 2 | 1 | 3 |
2021 | 0 | 1 | 1 |
2022 | 1 | 0 | 1 |
2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Sodium-Phosphate Cotransporter Proteins, Type IIa" by people in Profiles.
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The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function. J Am Soc Nephrol. 2024 Apr 01; 35(4):441-455.
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Acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals. Acta Physiol (Oxf). 2022 06; 235(2):e13815.
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Fibroblast growth factor 23 leads to endolysosomal routing of the renal phosphate cotransporters NaPi-IIa and NaPi-IIc in vivo. Am J Physiol Renal Physiol. 2021 12 01; 321(6):F785-F798.
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Mild Idiopathic Infantile Hypercalcemia-Part 1: Biochemical and Genetic Findings. J Clin Endocrinol Metab. 2021 09 27; 106(10):2915-2937.
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Selective pharmacological inhibition of the sodium-dependent phosphate cotransporter NPT2a promotes phosphate excretion. J Clin Invest. 2020 12 01; 130(12):6510-6522.
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Nephrolithiasis from an Unexpected Cause: Phosphaturia. Am J Med. 2021 02; 134(2):e131-e132.
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Digenic Heterozygous Mutations in SLC34A3 and SLC34A1 Cause Dominant Hypophosphatemic Rickets with Hypercalciuria. J Clin Endocrinol Metab. 2020 07 01; 105(7).
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Expression of NaPi-IIb in rodent and human kidney and upregulation in a model of chronic kidney disease. Pflugers Arch. 2020 04; 472(4):449-460.
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1,25-Dihydroxyvitamin D Maintains Brush Border Membrane NaPi2a and Attenuates Phosphaturia in Hyp Mice. Endocrinology. 2019 10 01; 160(10):2204-2214.
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Gene panel sequencing identifies a likely monogenic cause in 7% of 235 Pakistani families with nephrolithiasis. Hum Genet. 2019 Mar; 138(3):211-219.