STAT1 Transcription Factor

"STAT1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.

Descriptor ID

D050794

MeSH Number(s)

D12.644.360.024.303.500.500

D12.644.360.024.342.100

D12.776.157.057.061.500.500

D12.776.157.057.186.100

D12.776.260.513.249.500

D12.776.476.024.386.500.500

D12.776.476.024.421.100

D12.776.930.354.249.500

D12.776.930.840.100

Concept/Terms

STAT1 Transcription Factor

Below are MeSH descriptors whose meaning is more general than "STAT1 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Interferon-Stimulated Gene Factor 3 [D12.644.360.024.303]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.644.360.024.303.500]
STAT1 Transcription Factor [D12.644.360.024.303.500.500]
STAT Transcription Factors [D12.644.360.024.342]
STAT1 Transcription Factor [D12.644.360.024.342.100]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Interferon-Stimulated Gene Factor 3 [D12.776.157.057.061]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.157.057.061.500]
STAT1 Transcription Factor [D12.776.157.057.061.500.500]
STAT Transcription Factors [D12.776.157.057.186]
STAT1 Transcription Factor [D12.776.157.057.186.100]
DNA-Binding Proteins [D12.776.260]
Interferon-Stimulated Gene Factor 3 [D12.776.260.513]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.260.513.249]
STAT1 Transcription Factor [D12.776.260.513.249.500]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
STAT Transcription Factors [D12.776.476.024.421]
STAT1 Transcription Factor [D12.776.476.024.421.100]
Transcription Factors [D12.776.930]
Interferon-Stimulated Gene Factor 3 [D12.776.930.354]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.930.354.249]
STAT1 Transcription Factor [D12.776.930.354.249.500]
STAT Transcription Factors [D12.776.930.840]
STAT1 Transcription Factor [D12.776.930.840.100]

Below are MeSH descriptors whose meaning is related to "STAT1 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "STAT1 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "STAT1 Transcription Factor" by people in Harvard Catalyst Profiles by year, and whether "STAT1 Transcription Factor" was a major or minor topic of these publication.

Bar chart showing 209 publications over 30 distinct years, with a maximum of 13 publications in 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	1	1
1996	0	5	5
1997	0	4	4
1998	0	1	1
1999	0	11	11
2000	0	13	13
2001	0	6	6
2002	0	7	7
2003	0	10	10
2004	0	9	9
2005	2	5	7
2006	5	4	9
2007	5	3	8
2008	2	3	5
2009	4	4	8
2010	4	3	7
2011	0	2	2
2012	2	8	10
2013	2	10	12
2014	2	5	7
2015	5	6	11
2016	5	5	10
2017	2	8	10
2018	4	5	9
2019	3	4	7
2020	0	3	3
2021	3	8	11
2022	0	3	3
2023	0	2	2

Below are the most recent publications written about "STAT1 Transcription Factor" by people in Profiles.

Emapalumab as bridge to hematopoietic cell transplant for STAT1 gain-of-function mutations. J Allergy Clin Immunol. 2023 09; 152(3):815-817.

View in: PubMed
Human inherited complete STAT2 deficiency underlies inflammatory viral diseases. J Clin Invest. 2023 06 15; 133(12).

View in: PubMed
Non-canonical STAT3 function reduces REDD1 transcription. FEBS J. 2023 04; 290(7):1765-1781.

View in: PubMed
Impairment of the NKT-STAT1-CXCL9 Axis Contributes to Vessel Fibrosis in Pulmonary Hypertension Caused by Lung Fibrosis. Am J Respir Crit Care Med. 2022 10 15; 206(8):981-998.

View in: PubMed
JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia. Med (N Y). 2022 01 14; 3(1):42-57.e5.

View in: PubMed
Self-reactivity controls functional diversity of naive CD8+ T cells by co-opting tonic type I interferon. Nat Commun. 2021 10 18; 12(1):6059.

View in: PubMed
High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells. J Radiat Res. 2021 Sep 13; 62(5):773-781.

View in: PubMed
Genetic, Immunological, and Clinical Features of 32 Patients with Autosomal Recessive STAT1 Deficiency. J Immunol. 2021 07 01; 207(1):133-152.

View in: PubMed
An activity-dependent determinant of synapse elimination in the mammalian brain. Neuron. 2021 04 21; 109(8):1333-1349.e6.

View in: PubMed
Study of Tofacitinib in Refractory Dermatomyositis: An Open-Label Pilot Study of Ten Patients. Arthritis Rheumatol. 2021 05; 73(5):858-865.

View in: PubMed

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