Germ Layers

"Germ Layers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The three primary germinal layers (ECTODERM; ENDODERM; and MESODERM) developed during GASTRULATION that provide tissues and body plan of a mature organism. They derive from two early layers, hypoblast and epiblast.

Descriptor ID

D005855

MeSH Number(s)

A16.504

Concept/Terms

Germ Layers

Hypoblast

Epiblast

Below are MeSH descriptors whose meaning is more general than "Germ Layers".

Anatomy [A]
Embryonic Structures [A16]
Germ Layers [A16.504]

Below are MeSH descriptors whose meaning is related to "Germ Layers".

Below are MeSH descriptors whose meaning is more specific than "Germ Layers".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Germ Layers" by people in Harvard Catalyst Profiles by year, and whether "Germ Layers" was a major or minor topic of these publication.

Bar chart showing 47 publications over 18 distinct years, with a maximum of 8 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2005	1	0	1
2007	1	2	3
2009	0	1	1
2010	0	1	1
2011	5	1	6
2012	0	1	1
2013	1	1	2
2014	1	1	2
2015	1	3	4
2016	0	4	4
2017	1	0	1
2018	1	2	3
2019	1	3	4
2020	0	1	1
2021	3	5	8
2022	2	0	2
2023	0	2	2

Below are the most recent publications written about "Germ Layers" by people in Profiles.

Intersection clock reveals a rejuvenation event during human embryogenesis. Aging Cell. 2023 10; 22(10):e13922.

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Time space and single-cell resolved tissue lineage trajectories and laterality of body plan at gastrulation. Nat Commun. 2023 09 14; 14(1):5675.

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Single-cell analysis of embryoids reveals lineage diversification roadmaps of early human development. Cell Stem Cell. 2022 09 01; 29(9):1402-1419.e8.

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Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming. Elife. 2022 08 15; 11.

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An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates. Cell Rep Methods. 2022 07 18; 2(7):100244.

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Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics. Nat Cell Biol. 2022 06; 24(6):833-844.

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Modulating mesendoderm competence during human germ layer differentiation. Cell Rep. 2021 11 09; 37(6):109990.

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Integrated loss- and gain-of-function screens define a core network governing human embryonic stem cell behavior. Genes Dev. 2021 11 01; 35(21-22):1527-1547.

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Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation. Stem Cell Reports. 2021 11 09; 16(11):2628-2641.

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Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3. Nat Commun. 2021 06 21; 12(1):3804.

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