Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Receptors, N-Methyl-D-Aspartate

"Receptors, N-Methyl-D-Aspartate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.


This graph shows the total number of publications written about "Receptors, N-Methyl-D-Aspartate" by people in Harvard Catalyst Profiles by year, and whether "Receptors, N-Methyl-D-Aspartate" was a major or minor topic of these publication.
Bar chart showing 595 publications over 30 distinct years, with a maximum of 28 publications in 2004 and 2011
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.