Leishmania major

"Leishmania major" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) of the Old World. Transmission is by Phlebotomus sandflies.

Descriptor ID

D018320

MeSH Number(s)

B01.268.475.868.488.405

Concept/Terms

Leishmania major

Below are MeSH descriptors whose meaning is more general than "Leishmania major".

Organisms [B]
Eukaryota [B01]
Euglenozoa [B01.268]
Kinetoplastida [B01.268.475]
Trypanosomatina [B01.268.475.868]
Leishmania [B01.268.475.868.488]
Leishmania major [B01.268.475.868.488.405]

Below are MeSH descriptors whose meaning is related to "Leishmania major".

Below are MeSH descriptors whose meaning is more specific than "Leishmania major".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leishmania major" by people in Harvard Catalyst Profiles by year, and whether "Leishmania major" was a major or minor topic of these publication.

Bar chart showing 43 publications over 24 distinct years, with a maximum of 4 publications in 1997 and 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1995	1	0	1
1996	1	0	1
1997	3	1	4
1998	1	0	1
1999	1	1	2
2000	2	2	4
2001	1	0	1
2002	2	1	3
2003	1	0	1
2004	0	2	2
2005	1	1	2
2007	3	0	3
2008	1	0	1
2009	1	1	2
2010	1	0	1
2012	1	0	1
2013	1	0	1
2014	3	0	3
2016	1	1	2
2018	2	0	2
2019	2	0	2
2020	1	0	1
2021	1	0	1

Below are the most recent publications written about "Leishmania major" by people in Profiles.

Successful Isolation of Leishmania RNA Virus (LRV) from Leishmania major in a Cutaneous Leishmaniasis Focus in Central Iran: An Update on Cases. Acta Parasitol. 2022 Sep; 67(3):1290-1298.

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Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression. J Biol Chem. 2021 10; 297(4):101198.

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Regulation of Leishmania major PAS domain-containing phosphoglycerate kinase by cofactor Mg2+ ion at neutral pH. FEBS J. 2020 12; 287(23):5183-5195.

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Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. Front Cell Infect Microbiol. 2019; 9:280.

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PAS domain-containing phosphoglycerate kinase deficiency in Leishmania major results in increased autophagosome formation and cell death. Biochem J. 2019 04 30; 476(8):1303-1321.

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Loss of virulence in NAD(P)H cytochrome b5 oxidoreductase deficient Leishmania major. Biochem Biophys Res Commun. 2018 09 03; 503(1):371-377.

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Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major. Nucleic Acids Res. 2018 04 20; 46(7):3791-3801.

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Cryotherapy of cutaneous leishmaniasis caused by Leishmania major in BALB/c mice: A comparative experimental study. J Vector Borne Dis. 2018 Jan-Mar; 55(1):42-46.

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Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation. Cell Host Microbe. 2017 Jul 12; 22(1):13-24.e4.

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Comparative genomics of Tunisian Leishmania major isolates causing human cutaneous leishmaniasis with contrasting clinical severity. Infect Genet Evol. 2017 06; 50:110-120.

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