Receptors, TNF-Related Apoptosis-Inducing Ligand
"Receptors, TNF-Related Apoptosis-Inducing Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved death domains that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
MeSH Number(s)
D12.776.543.750.073.600
D12.776.543.750.705.852.760.396
Concept/Terms
Receptors, TNF-Related Apoptosis-Inducing Ligand- Receptors, TNF-Related Apoptosis-Inducing Ligand
- Receptors, TNF Related Apoptosis Inducing Ligand
- Tumor Necrosis Factor Receptor Superfamily, Member 10
- TNF-Related Apoptosis-Inducing Ligand Receptors
- TNF Related Apoptosis Inducing Ligand Receptors
- TRAIL Receptors
- Receptors, TRAIL
- Receptors, Tumor Necrosis Factor, Member 10
Receptors, Tumor Necrosis Factor, Member 10d- Receptors, Tumor Necrosis Factor, Member 10d
- TRAIL Receptor 4
- Receptor 4, TRAIL
- Receptor, TRAIL-4
- Receptor, TRAIL 4
- TRAIL-4 Receptor
- DCR2 Receptor
- Receptor, DCR2
- Decoy Receptor 2, Tumor Necrosis Factor
Receptors, Tumor Necrosis Factor, Member 10a- Receptors, Tumor Necrosis Factor, Member 10a
- Death Receptor-4
- Death Receptor 4
- Receptor-4, Death
- Tumor Necrosis Factor Receptor Superfamily, Member 10a
- Receptor, TRAIL-1
- Receptor, TRAIL 1
- TRAIL-1 Receptor
- TRAIL Receptor 1
- APO2 Receptor
- Receptor, APO2
- DR4 Receptor
- Receptor, DR4
Receptors, Tumor Necrosis Factor, Member 10b- Receptors, Tumor Necrosis Factor, Member 10b
- Death Receptor-5
- Death Receptor 5
- TRAIL Receptor 2
- Receptor, TRAIL-2
- Receptor, TRAIL 2
- TRAIL-2 Receptor
- TNF-Related Apoptosis-Inducing Ligand Receptor 2
- TNF Related Apoptosis Inducing Ligand Receptor 2
- Tumor Necrosis Factor Receptor Superfamily, Member 10b
- DR5 Receptor
- Receptor, DR5
Below are MeSH descriptors whose meaning is more general than "Receptors, TNF-Related Apoptosis-Inducing Ligand".
Below are MeSH descriptors whose meaning is more specific than "Receptors, TNF-Related Apoptosis-Inducing Ligand".
This graph shows the total number of publications written about "Receptors, TNF-Related Apoptosis-Inducing Ligand" by people in Harvard Catalyst Profiles by year, and whether "Receptors, TNF-Related Apoptosis-Inducing Ligand" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 2 | 3 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 3 | 5 |
| 2015 | 1 | 2 | 3 |
| 2017 | 2 | 2 | 4 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 2 | 4 |
| 2021 | 2 | 3 | 5 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptors, TNF-Related Apoptosis-Inducing Ligand" by people in Profiles.
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Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation. Cell Res. 2023 02; 33(2):131-146.
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Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo. Cancer Biol Ther. 2021 12 02; 22(10-12):607-618.
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Antitumorigenic effect of combination treatment with ONC201 and TRAIL in endometrial cancer in vitro and in vivo. Cancer Biol Ther. 2021 12 02; 22(10-12):554-563.
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An anti-DR5 antibody-curcumin conjugate for the enhanced clearance of activated hepatic stellate cells. Int J Biol Macromol. 2021 Dec 01; 192:1231-1239.
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BAP1 and YY1 regulate expression of death receptors in malignant pleural mesothelioma. J Biol Chem. 2021 11; 297(5):101223.
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Genetic associations of central serous chorioretinopathy: a systematic review and meta-analysis. Br J Ophthalmol. 2022 11; 106(11):1542-1548.
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Generation of TRAIL-resistant cell line models reveals distinct adaptive mechanisms for acquired resistance and re-sensitization. Oncogene. 2021 05; 40(18):3201-3216.
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Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas. Sci Rep. 2021 03 18; 11(1):6392.
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Selective Tumor Cell Apoptosis and Tumor Regression in CDH17-Positive Colorectal Cancer Models using BI 905711, a Novel Liver-Sparing TRAILR2 Agonist. Mol Cancer Ther. 2021 01; 20(1):96-108.
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TRAIL of Hope Meeting Resistance in Cancer. Trends Cancer. 2020 12; 6(12):989-1001.