Edward Thomas Ryan, D.T.M.&H., M.D.
|Title||Professor of Medicine|
|Institution||Massachusetts General Hospital|
|Address||Massachusetts General Hospital|
Infectious Disease - Jackson 504
55 Fruit St
Boston MA 02114
|Title||Professor in the Department of Immunology and Infectious Diseases|
|Institution||Harvard School of Public Health|
Available: 09/01/11, Expires: 06/01/15
Globally, one in five people dies of an infection, and this reality
is projected to continue for the next 50 years. Intestinal and respiratory
infections are the two leading infectious causes of death, far exceeding
malaria, TB and HIV. Our research focuses on understanding host-pathogen
interactions during two intestinal infections that disproportionally affect the
most impoverished and disenfranchised, typhoid and cholera. These two illnesses
affect over 25 million people each year, killing 300,000. Our research focuses
on studying these human-restricted infections, especially regarding the
discovery and development of improved vaccines, improved immunization
strategies, and improved diagnostics. We perform this work through an
established collaborative effort with researchers at the International Centre
for Diarrhoeal Disease Research in Dhaka, Bangladesh (ICDDR,B). Particular areas
of focus include the application of high throughput genomic, proteomic, and
immunoproteomic platform technologies to infections. Students would be welcome
to join an active NIH-funded research program. Research would be bench-based in
Boston, with potential in Bangladesh. Interested students can contact Dr. Ryan
to discuss potential involvement and projects.
Development of an improved cholera vaccine: evaluation of the effects of vaccine preparation on intramuscular cholera conjugate vaccine efficacy
Full Time, 06/06/12 - 08/14/12
Development of an improved cholera vaccine: evaluation of a combination oral prime-intramuscular cholera conjugate vaccine boost approach
Summer, 05/07/12 - 08/10/12
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