 Christos Polytarchou, PH.D.
| Title | Research Fellow in Pathology (EXT) |
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| Institution | Dana-Farber Cancer Institute |
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| Department | Pathology |
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| Address | Dana-Farber Cancer Institute
Smith 702
44 Binney St
Boston MA 02115
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| Phone | 617/582-9696 |
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| Fax | 617/582-9610 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Koutsioumpa M, Polytarchou C, Courty J, Zhang Y, Kieffer N, Mikelis C, Skandalis SS, Hellman U, Iliopoulos D, Papadimitriou E. Interplay between avß3 Integrin and Nucleolin Regulates Human Endothelial and Glioma Cell Migration. J Biol Chem. 2013 Jan 4; 288(1):343-54.
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Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci U S A. 2012 Sep 4; 109(36):14470-5.
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Ezell SA, Polytarchou C, Hatziapostolou M, Guo A, Sanidas I, Bihani T, Comb MJ, Sourvinos G, Tsichlis PN. The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY. Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10):E613-21.
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Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, Ogata H, Karin M, Struhl K, Hadzopoulou-Cladaras M, Iliopoulos D. An HNF4a-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell. 2011 Dec 9; 147(6):1233-47.
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Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell. 2011 Nov 23; 147(5):1066-79.
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Hatziapostolou M, Koukos G, Polytarchou C, Kottakis F, Serebrennikova O, Kuliopulos A, Tsichlis PN. Tumor progression locus 2 mediates signal-induced increases in cytoplasmic calcium and cell migration. Sci Signal. 2011 Aug 23; 4(187):ra55.
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Bakirtzi K, Hatziapostolou M, Karagiannides I, Polytarchou C, Jaeger S, Iliopoulos D, Pothoulakis C. Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors. Gastroenterology. 2011 Nov; 141(5):1749-61.e1.
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Kottakis F, Polytarchou C, Foltopoulou P, Sanidas I, Kampranis SC, Tsichlis PN. FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway. Mol Cell. 2011 Jul 22; 43(2):285-98.
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Polytarchou C, Iliopoulos D, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, Tsichlis PN. Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Res. 2011 Jul 1; 71(13):4720-31.
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Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell. 2010 Sep 10; 39(5):761-72.
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Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou IG, Struhl K, Tsichlis PN. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Sci Signal. 2009; 2(92):ra62.
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Polytarchou C, Hatziapostolou M, Poimenidi E, Mikelis C, Papadopoulou A, Parthymou A, Papadimitriou E. Nitric oxide stimulates migration of human endothelial and prostate cancer cells through up-regulation of pleiotrophin expression and its receptor protein tyrosine phosphatase beta/zeta. Int J Cancer. 2009 Apr 15; 124(8):1785-93.
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Polytarchou C, Pfau R, Hatziapostolou M, Tsichlis PN. The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress. Mol Cell Biol. 2008 Dec; 28(24):7451-64.
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Hatziapostolou M, Polytarchou C, Panutsopulos D, Covic L, Tsichlis PN. Proteinase-activated receptor-1-triggered activation of tumor progression locus-2 promotes actin cytoskeleton reorganization and cell migration. Cancer Res. 2008 Mar 15; 68(6):1851-61.
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Hatziapostolou M, Polytarchou C, Katsoris P, Courty J, Papadimitriou E. Heparin affin regulatory peptide/pleiotrophin mediates fibroblast growth factor 2 stimulatory effects on human prostate cancer cells. J Biol Chem. 2006 Oct 27; 281(43):32217-26.
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Polytarchou C, Kardamakis D, Katsoris P, Papadimitriou E. Antioxidants modify the effect of X rays on blood vessels. Anticancer Res. 2006 Jul-Aug; 26(4B):3043-7.
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Hatziapostolou M, Delbe J, Katsoris P, Polytarchou C, Courty J, Papadimitriou E. Heparin affin regulatory peptide is a key player in prostate cancer cell growth and angiogenicity. Prostate. 2005 Oct 1; 65(2):151-8.
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Polytarchou C, Hatziapostolou M, Papadimitriou E. Hydrogen peroxide stimulates proliferation and migration of human prostate cancer cells through activation of activator protein-1 and up-regulation of the heparin affin regulatory peptide gene. J Biol Chem. 2005 Dec 9; 280(49):40428-35.
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Polytarchou C, Papadimitriou E. Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity. Eur J Pharmacol. 2005 Mar 7; 510(1-2):31-8.
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Papadimitriou E, Polykratis A, Hatziapostolou M, Parthymou A, Polytarchou C, Mikelis C. Heparin affin regulatory peptide: a new target for tumour therapy? Curr Cancer Drug Targets. 2004 Sep; 4(6):471-82.
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Polytarchou C, Gligoris T, Kardamakis D, Kotsaki E, Papadimitriou E. X-rays affect the expression of genes involved in angiogenesis. Anticancer Res. 2004 Sep-Oct; 24(5A):2941-5.
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Polytarchou C, Papadimitriou E. Antioxidants inhibit angiogenesis in vivo through down-regulation of nitric oxide synthase expression and activity. Free Radic Res. 2004 May; 38(5):501-8.
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Giannopoulou E, Katsoris P, Polytarchou C, Papadimitriou E. Nitration of cytoskeletal proteins in the chicken embryo chorioallantoic membrane. Arch Biochem Biophys. 2002 Apr 15; 400(2):188-98.
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Giannopoulou E, Katsoris P, Hatziapostolou M, Kardamakis D, Kotsaki E, Polytarchou C, Parthymou A, Papaioannou S, Papadimitriou E. X-rays modulate extracellular matrix in vivo. Int J Cancer. 2001 Dec 1; 94(5):690-8.
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