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Taranjit Singh Gujral, PH.D.

TitleResearch Fellow in Systems Biology (INT)
InstitutionHarvard Medical School
DepartmentSystems Biology
AddressHarvard Medical School
Systems Biology
200 Longwood Ave
Boston MA 02115
Phone617/417-7278

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gujral TS, Peshkin L, Kirschner MW. Exploiting polypharmacology for drug target deconvolution. Proc Natl Acad Sci U S A. 2014 Apr 1; 111(13):5048-53.
    View in: PubMed
  2. Gujral TS, Karp ES, Chan M, Chang BH, Macbeath G. Family-wide Investigation of PDZ Domain-Mediated Protein-Protein Interactions Implicates ß-Catenin in Maintaining the Integrity of Tight Junctions. Chem Biol. 2013 Jun 20; 20(6):816-27.
    View in: PubMed
  3. Gujral TS, Karp RL, Finski A, Chan M, Schwartz PE, Macbeath G, Sorger P. Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays. Oncogene. 2013 Jul 18; 32(29):3470-6.
    View in: PubMed
  4. Hyndman BD, Gujral TS, Krieger JR, Cockburn JG, Mulligan LM. Multiple Functional Effects of RET Kinase Domain Sequence Variants in Hirschsprung Disease. Hum Mutat. 2013 Jan; 34(1):132-42.
    View in: PubMed
  5. Luckert K, Gujral TS, Chan M, Sevecka M, Joos TO, Sorger PK, Macbeath G, Pötz O. A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins. Sci Signal. 2012 Jan 10; 5(206):pl1.
    View in: PubMed
  6. Chang BH, Gujral TS, Karp ES, BuKhalid R, Grantcharova VP, MacBeath G. A systematic family-wide investigation reveals that ~30% of mammalian PDZ domains engage in PDZ-PDZ interactions. Chem Biol. 2011 Sep 23; 18(9):1143-52.
    View in: PubMed
  7. Cockburn JG, Richardson DS, Gujral TS, Mulligan LM. RET-mediated cell adhesion and migration require multiple integrin subunits. J Clin Endocrinol Metab. 2010 Nov; 95(11):E342-6.
    View in: PubMed
  8. Gujral TS, MacBeath G. A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation. PLoS One. 2010; 5(4):e10024.
    View in: PubMed
  9. Shalek AK, Robinson JT, Karp ES, Lee JS, Ahn DR, Yoon MH, Sutton A, Jorgolli M, Gertner RS, Gujral TS, MacBeath G, Yang EG, Park H. Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells. Proc Natl Acad Sci U S A. 2010 Feb 2; 107(5):1870-5.
    View in: PubMed
  10. Gujral TS, MacBeath G. Emerging miniaturized proteomic technologies to study cell signaling in clinical samples. Sci Signal. 2009; 2(93):pe65.
    View in: PubMed
  11. Richardson DS, Gujral TS, Peng S, Asa SL, Mulligan LM. Transcript level modulates the inherent oncogenicity of RET/PTC oncoproteins. Cancer Res. 2009 Jun 1; 69(11):4861-9.
    View in: PubMed
  12. Gujral TS, van Veelen W, Richardson DS, Myers SM, Meens JA, Acton DS, Duñach M, Elliott BE, Höppener JW, Mulligan LM. A novel RET kinase-beta-catenin signaling pathway contributes to tumorigenesis in thyroid carcinoma. Cancer Res. 2008 Mar 1; 68(5):1338-46.
    View in: PubMed
  13. Lai AZ, Gujral TS, Mulligan LM. RET signaling in endocrine tumors: delving deeper into molecular mechanisms. Endocr Pathol. 2007; 18(2):57-67.
    View in: PubMed
  14. Gujral TS, Singh VK, Jia Z, Mulligan LM. Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2B. Cancer Res. 2006 Nov 15; 66(22):10741-9.
    View in: PubMed
  15. Gujral TS, Mulligan LM. Molecular implications of RET mutations for pheochromocytoma risk in multiple endocrine neoplasia 2. Ann N Y Acad Sci. 2006 Aug; 1073:234-40.
    View in: PubMed
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