Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Hao Wu, Ph.D.

TitlePost-Doctoral Fellow in Stem Cell & Regenerative Biology (EXT)
InstitutionFaculty of Arts & Sciences
DepartmentStem Cell and Regenerative Biology
AddressChien Laboratory, Department of SCRB
Sherman Fairchild Biochemistry Bldg
7 Divinity Ave
Cambridge MA 02138
Phone617/643-3440
Fax617/643-3451

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Shen L, Wu H, Diep D, Yamaguchi S, D'Alessio AC, Fung HL, Zhang K, Zhang Y. Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics. Cell. 2013 Apr 16.
    View in: PubMed
  2. He J, Shen L, Wan M, Taranova O, Wu H, Zhang Y. Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes. Nat Cell Biol. 2013 Apr; 15(4):373-84.
    View in: PubMed
  3. Soh BS, Wu H, Chien KR. Cardiac regenerative medicine 2.0. Nat Biotechnol. 2013 Mar; 31(3):209-11.
    View in: PubMed
  4. Wu H, Zhang Y. Early embryos reprogram DNA methylation in two steps. Cell Stem Cell. 2012 May 4; 10(5):487-9.
    View in: PubMed
  5. Wu H, Tao J, Sun YE. Regulation and function of mammalian DNA methylation patterns: a genomic perspective. Brief Funct Genomics. 2012 May; 11(3):240-50.
    View in: PubMed
  6. Wu H, Zhang Y. Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev. 2011 Dec 1; 25(23):2436-52.
    View in: PubMed
  7. Xu H, Yi BA, Wu H, Bock C, Gu H, Lui KO, Park JH, Shao Y, Riley AK, Domian IJ, Hu E, Willette R, Lepore J, Meissner A, Wang Z, Chien KR. Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature. Cell Res. 2012 Jan; 22(1):142-54.
    View in: PubMed
  8. Wu H, Zhang Y. Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells. Cell Cycle. 2011 Aug 1; 10(15):2428-36.
    View in: PubMed
  9. Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. J Neurosci. 2011 Jun 1; 31(22):8306-19.
    View in: PubMed
  10. Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 2011 Apr 1; 25(7):679-84.
    View in: PubMed
  11. Wu H, D'Alessio AC, Ito S, Xia K, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature. 2011 May 19; 473(7347):389-93.
    View in: PubMed
  12. Wu H, Tao J, Chen PJ, Shahab A, Ge W, Hart RP, Ruan X, Ruan Y, Sun YE. Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):18161-6.
    View in: PubMed
  13. Wu H, Coskun V, Tao J, Xie W, Ge W, Yoshikawa K, Li E, Zhang Y, Sun YE. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science. 2010 Jul 23; 329(5990):444-8.
    View in: PubMed
  14. Goff LA, Davila J, Swerdel MR, Moore JC, Cohen RI, Wu H, Sun YE, Hart RP. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PLoS One. 2009; 4(9):e7192.
    View in: PubMed
  15. Wu H, Sun YE. Reversing DNA methylation: new insights from neuronal activity-induced Gadd45b in adult neurogenesis. Sci Signal. 2009 Mar 31; 2(64):pe17.
    View in: PubMed
  16. Tao J, Hu K, Chang Q, Wu H, Sherman NE, Martinowich K, Klose RJ, Schanen C, Jaenisch R, Wang W, Sun YE. Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4882-7.
    View in: PubMed
  17. Tao J, Wu H, Sun YE. Deciphering Rett syndrome with mouse genetics, epigenomics, and human neurons. Int Rev Neurobiol. 2009; 89:147-60.
    View in: PubMed
  18. Wu H, Kim KJ, Mehta K, Paxia S, Sundstrom A, Anantharaman T, Kuraishy AI, Doan T, Ghosh J, Pyle AD, Clark A, Lowry W, Fan G, Baxter T, Mishra B, Sun Y, Teitell MA. Copy number variant analysis of human embryonic stem cells. Stem Cells. 2008 Jun; 26(6):1484-9.
    View in: PubMed
  19. Coskun V, Wu H, Blanchi B, Tsao S, Kim K, Zhao J, Biancotti JC, Hutnick L, Krueger RC, Fan G, de Vellis J, Sun YE. CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain. Proc Natl Acad Sci U S A. 2008 Jan 22; 105(3):1026-31.
    View in: PubMed
  20. Saxe JP, Wu H, Kelly TK, Phelps ME, Sun YE, Kornblum HI, Huang J. A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Chem Biol. 2007 Sep; 14(9):1019-30.
    View in: PubMed
  21. Wu H, Xu J, Pang ZP, Ge W, Kim KJ, Blanchi B, Chen C, Südhof TC, Sun YE. Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A. 2007 Aug 21; 104(34):13821-6.
    View in: PubMed
  22. Bredy TW, Wu H, Crego C, Zellhoefer J, Sun YE, Barad M. Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learn Mem. 2007 Apr; 14(4):268-76.
    View in: PubMed
  23. Wu H, Sun YE. Epigenetic regulation of stem cell differentiation. Pediatr Res. 2006 Apr; 59(4 Pt 2):21R-5R.
    View in: PubMed
  24. Krueger RC, Wu H, Zandian M, Danielpour M, Kabos P, Yu JS, Sun YE. Neural progenitors populate the cerebrospinal fluid of preterm patients with hydrocephalus. J Pediatr. 2006 Mar; 148(3):337-340.
    View in: PubMed
  25. Sun YE, Wu H. The ups and downs of BDNF in Rett syndrome. Neuron. 2006 Feb 2; 49(3):321-3.
    View in: PubMed
  26. Ge W, He F, Kim KJ, Blanchi B, Coskun V, Nguyen L, Wu X, Zhao J, Heng JI, Martinowich K, Tao J, Wu H, Castro D, Sobeih MM, Corfas G, Gleeson JG, Greenberg ME, Guillemot F, Sun YE. Coupling of cell migration with neurogenesis by proneural bHLH factors. Proc Natl Acad Sci U S A. 2006 Jan 31; 103(5):1319-24.
    View in: PubMed
  27. Fan G, Martinowich K, Chin MH, He F, Fouse SD, Hutnick L, Hattori D, Ge W, Shen Y, Wu H, ten Hoeve J, Shuai K, Sun YE. DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development. 2005 Aug; 132(15):3345-56.
    View in: PubMed
  28. He F, Ge W, Martinowich K, Becker-Catania S, Coskun V, Zhu W, Wu H, Castro D, Guillemot F, Fan G, de Vellis J, Sun YE. A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nat Neurosci. 2005 May; 8(5):616-25.
    View in: PubMed
  29. Li X, Liu X, Lou Z, Duan X, Wu H, Liu Y, Rao Z. Crystal structure of human coactosin-like protein at 1.9 A resolution. Protein Sci. 2004 Nov; 13(11):2845-51.
    View in: PubMed
  30. Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y, Fan G, Sun YE. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science. 2003 Oct 31; 302(5646):890-3.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: FAS faculty should contact the Office for Scholarly Communication (oschulmail.harvard.edu) for general questions about Profiles. For data questions, please contact Raelyn Lincoln (raelyn_lincolnharvard.edu) from the FAS Division of Science; Jennifer Shephard (jmshephfas.harvard.edu) from the FAS Division of Social Science; or Alexander Parker (afparkerfas.harvard.edu) from the FAS Division of Arts and Humanities.
Wu's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department