 Elliot L. Chaikof, Ph.D., M.D.
| Title | Johnson and Johnson Professor of Surgery |
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| Institution | Beth Israel Deaconess Medical Center |
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| Department | Surgery |
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| Address | Beth Israel Deaconess Medical Center
Suite 9F
110 Francis Street
Boston MA 02215
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| Phone | 617/632-9581 |
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| Fax | 617/632-9701 |
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| Title | Head of the Department of Surgery at the Beth Israel Deaconess Medical Center |
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| Institution | Beth Israel Deaconess Medical Center |
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| Department | Surgery |
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 Biography | 1976 -
| Ann Shepard Biology Award | | 1977 -
| Ann Shepard Zoology Award | | 1979 -
| Phi Beta Kappa | | 1982 -
| Alpha Omega Alpha | | 1988 -
| Sigma Xi | | 1996 -
| E.J. Wylie Fellowship | | 1999 -
| Distinguished Fellow | | 2002 -
| Woodruff Fund Teaching Award | | 2003 -
| Harvard-Longwood Visiting Professor | | 2004 -
| Member | | 2005 -
| Fellow | | 2006 -
| Member | | 2008 -
| John Mannick Visiting Professor | | 2008 -
2010 | President | | 2010 -
| Milton F. Bryant Lecture | | 2011 -
| Brandi Rutherford Lecture | | 2011 -
| Emile Holman Lecture | | 2012 -
| Charles B. Huggins Lecture |
Overview Dr. Chaikof was born and raised in Toronto and earned BA and MD degrees at the Johns Hopkins University in Baltimore. He completed a residency in general surgery at the Massachusetts General Hospital and while a surgical resident, received a PhD in Chemical Engineering at the Massachusetts Institute of Technology with a focus on artificial organs and the design of biomaterials for reconstructive surgery. Following his surgical training in Boston, he completed additional training in Vascular Surgery at the Emory University School of Medicine where he joined the surgical faculty, most recently holding the John E. Skandalakis Chair of Surgery at Emory University, serving as Chief of Vascular Surgery and Director of the Residency in Vascular Surgery. While at Emory University, Dr. Chaikof held secondary appointments as an Adjunct Professor in the School of Chemical and Biomolecular Engineering at the Georgia Institute of Technology and was a member of the faculty in the Department of Biomedical Engineering.
In 2010, Dr. Chaikof was appointed as the Johnson and Johnson Professor of Surgery at Harvard Medical School and Chairman of the Department of Surgery and Surgeon-in-Chief of the Beth Israel Deaconess Medical Center. A surgeon and biomedical engineer, he is a member of the Wyss Institute of Biological Inspired Engineering and the Harvard Stem Cell Institute. He is internationally recognized for his many original and innovative contributions to vascular surgery through his basic science, clinical, and translational studies. He has changed the way in which patient with aortic aneurysms are evaluated and treated. His work in biomedical engineering and materials science has lead to the development of an advance generation of cardiovascular materials, devices, cell based therapies and pharmacotherapeutics based upon the principles of biomimetics, molecular and tissue engineering, as well as micro- and nanofabrication technologies.
Lab web site: http://chaikoflab.org/
Mentoring Available: 09/01/11, Expires: 08/31/15 The control of blood clot formation on molecularly engineered surfaces remains a hurdle in the development of a small diameter arterial prosthesis critical to the fields of cardiac, plastic, and vascular surgery, as well as to the development of a permanently implantable artificial kidney, liver, or lung. We postulate that a clinically durable blood contacting surface can achieved by incorporating onto or within the material actively anti-thrombogenic mechanisms that are operative under a range of hemodynamic conditions. Ongoing research in our lab is directed at (i) engineering molecularly defined surfaces that prevent blood clotting in vitro and in vivo; and (ii) development of computational FEM models using MatchCad and Comsol programs that describe surface induced coagulation events under flow as a design tool for this effort. Available: 09/01/11, Expires: 08/31/15 At the beginning of the twenty-first century, we are witnessing a remarkable convergence of our synthetic and physical technologies with the world of molecular biology, which will provide unprecedented opportunities for the creation of novel, functional biomolecules using biosynthetic and chemical strategies. Our group is involved in the design of new approaches for the synthesis, assembly, and integration of artificial collagen and elastin fiber networks, neoproteoglycans, and biofunctional lipid membrane-mimetic systems for the fabrication of living artificial organs. Most applications are directed at the fabrication of cardiovascular organs (e.g. tissue engineered blood vessels, tissue engineered heart valves, novel stent designs, and endovascular grafts). Available: 09/01/11, Expires: 08/31/15 A significant obstacle in cell transplantation for the treatment of diabetes is the high rate of early islet destruction due to an “acute blood mediated inflammatory injury” that may also amplify subsequent immune reactions. Bio-orthogonal chemistry and recombinant gene technology can now be used to re-engineer living tissue surfaces, including pancreatic islets. In addition, ultrathin polymer films can be fabricated on islet surfaces as another means to re-engineer the biochemical landscape of the cell surface with incorporation of molecular inhibitors of local inflammatory events. The effectiveness of these strategies is being evaluated in vitro and in vivo. Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Siracuse JJ, Nandivada P, Giles KA, Hamdan AD, Wyers MC, Chaikof EL, Pomposelli FB, Schermerhorn ML. Prosthetic graft infections involving the femoral artery. J Vasc Surg. 2013 Mar; 57(3):700-5.
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Callery MP, Pratt WB, Kent TS, Chaikof EL, Vollmer CM. A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy. J Am Coll Surg. 2013 Jan; 216(1):1-14.
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Schermerhorn ML, Bensley RP, Giles KA, Hurks R, O'malley AJ, Cotterill P, Chaikof E, Landon BE. Changes in abdominal aortic aneurysm rupture and short-term mortality, 1995-2008: a retrospective observational study. Ann Surg. 2012 Oct; 256(4):651-8.
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Mets JM, Wilson JT, Cui W, Chaikof EL. An Automated Process for Layer-by-Layer Assembly of Polyelectrolyte Multilayer Thin Films on Viable Cell Aggregates. Adv Healthc Mater. 2013 Feb; 2(2):266-70.
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Ravi S, Caves JM, Martinez AW, Xiao J, Wen J, Haller CA, Davis ME, Chaikof EL. Effect of bone marrow-derived extracellular matrix on cardiac function after ischemic injury. Biomaterials. 2012 Nov; 33(31):7736-45.
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Jordan SW, Corriere MA, Vossen CY, Rosendaal FR, Chaikof EL. Flow-simulated thrombin generation profiles as a predictor of thrombotic risk among pre-menopausal women. Thromb Haemost. 2012 Aug; 108(2):258-65.
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Nandivada P, Lagisetty KH, Giles K, Pomposelli FB, Chaikof EL, Schermerhorn ML, Wyers MC, Hamdan AD. The impact of endovascular procedures on fellowship training in lower extremity revascularization. J Vasc Surg. 2012 Jun; 55(6):1814-20.
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Chaikof EL. Invited commentary. J Vasc Surg. 2012 May; 55(5):1304-5.
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Kim W, Brady C, Chaikof EL. Amphiphilic protein micelles for targeted in vivo imaging. Acta Biomater. 2012 Jul; 8(7):2476-82.
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Bensley RP, Hurks R, Huang Z, Pomposelli F, Hamdan A, Wyers M, Chaikof E, Schermerhorn ML. Ultrasound-guided percutaneous endovascular aneurysm repair success is predicted by access vessel diameter. J Vasc Surg. 2012 Jun; 55(6):1554-61.
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Siracuse JJ, Giles KA, Pomposelli FB, Hamdan AD, Wyers MC, Chaikof EL, Nedeau AE, Schermerhorn ML. Results for primary bypass versus primary angioplasty/stent for intermittent claudication due to superficial femoral artery occlusive disease. J Vasc Surg. 2012 Apr; 55(4):1001-7.
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Ravi S, Haller CA, Sallach RE, Chaikof EL. Cell behavior on a CCN1 functionalized elastin-mimetic protein polymer. Biomaterials. 2012 Mar; 33(8):2431-8.
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Xiao J, Angsana J, Wen J, Smith SV, Park PW, Ford ML, Haller CA, Chaikof EL. Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):386-96.
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Krishna UM, Martinez AW, Caves JM, Chaikof EL. Hydrazone self-crosslinking of multiphase elastin-like block copolymer networks. Acta Biomater. 2012 Mar; 8(3):988-97.
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Kim W, Xiao J, Chaikof EL. Recombinant amphiphilic protein micelles for drug delivery. Langmuir. 2011 Dec 6; 27(23):14329-34.
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Ravi S, Krishnamurthy VR, Caves JM, Haller CA, Chaikof EL. Maleimide-thiol coupling of a bioactive peptide to an elastin-like protein polymer. Acta Biomater. 2012 Feb; 8(2):627-35.
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Feng X, Chaikof EL, Absalon C, Drummond C, Taton D, Gnanou Y. Dendritic carrier based on PEG: design and degradation of acid-sensitive dendrimer-like poly(ethylene oxide)s. Macromol Rapid Commun. 2011 Nov 1; 32(21):1722-8.
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Jordan SW, Chaikof EL. Simulated surface-induced thrombin generation in a flow field. Biophys J. 2011 Jul 20; 101(2):276-86.
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Chung J, Kasirajan K, Veeraswamy RK, Dodson TF, Salam AA, Chaikof EL, Corriere MA. Left subclavian artery coverage during thoracic endovascular aortic repair and risk of perioperative stroke or death. J Vasc Surg. 2011 Oct; 54(4):979-84.
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Topcic D, Kim W, Holien JK, Jia F, Armstrong PC, Hohmann JD, Straub A, Krippner G, Haller CA, Domeij H, Hagemeyer CE, Parker MW, Chaikof EL, Peter K. An activation-specific platelet inhibitor that can be turned on/off by medically used hypothermia. Arterioscler Thromb Vasc Biol. 2011 Sep; 31(9):2015-23.
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Krishnamurthy VR, Dougherty A, Haller CA, Chaikof EL. Total synthesis and bioactivity of 18(R)-hydroxyeicosapentaenoic acid. J Org Chem. 2011 Jul 1; 76(13):5433-7.
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Caves JM, Cui W, Wen J, Kumar VA, Haller CA, Chaikof EL. Elastin-like protein matrix reinforced with collagen microfibers for soft tissue repair. Biomaterials. 2011 Aug; 32(23):5371-9.
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Murad MH, Montori VM, Sidawy AN, Ascher E, Meissner MH, Chaikof EL, Gloviczki P. Guideline methodology of the Society for Vascular Surgery including the experience with the GRADE framework. J Vasc Surg. 2011 May; 53(5):1375-80.
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Wilson JT, Cui W, Kozlovskaya V, Kharlampieva E, Pan D, Qu Z, Krishnamurthy VR, Mets J, Kumar V, Wen J, Song Y, Tsukruk VV, Chaikof EL. Cell surface engineering with polyelectrolyte multilayer thin films. J Am Chem Soc. 2011 May 11; 133(18):7054-64.
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Martinez AW, Chaikof EL. Microfabrication and nanotechnology in stent design. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011 May-Jun; 3(3):256-68.
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Naik N, Kumar V, Chaikof EL, Allen MG. MEMS-assisted spatially homogeneous endothelialization of a high length-to-depth aspect ratio microvascular network. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:290-3.
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Gupta N, Corriere MA, Dodson TF, Chaikof EL, Beaulieu RJ, Reeves JG, Salam AA, Kasirajan K. The incidence of microemboli to the brain is less with endarterectomy than with percutaneous revascularization with distal filters or flow reversal. J Vasc Surg. 2011 Feb; 53(2):316-22.
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Chung J, Corriere MA, Milner R, Kasirajan K, Salam A, Dodson TF, Chaikof EL, Veeraswamy RK. Midterm results of adjunctive neck therapies performed during elective infrarenal aortic aneurysm repair. J Vasc Surg. 2010 Dec; 52(6):1435-41.
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Qu Z, Chaikof EL. Interface between hemostasis and adaptive immunity. Curr Opin Immunol. 2010 Oct; 22(5):634-42.
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Fillinger MF, Greenberg RK, McKinsey JF, Chaikof EL. Reporting standards for thoracic endovascular aortic repair (TEVAR). J Vasc Surg. 2010 Oct; 52(4):1022-33, 1033.e15.
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Chung J, Corriere MA, Veeraswamy RK, Kasirajan K, Milner R, Dodson TF, Salam AA, Chaikof EL. Risk factors for late mortality after endovascular repair of the thoracic aorta. J Vasc Surg. 2010 Sep; 52(3):549-54; discussion 555.
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Cui W, Angsana J, Wen J, Chaikof EL. Liposomal formulations of thrombomodulin increase engraftment after intraportal islet transplantation. Cell Transplant. 2010; 19(11):1359-67.
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Caves JM, Kumar VA, Martinez AW, Kim J, Ripberger CM, Haller CA, Chaikof EL. The use of microfiber composites of elastin-like protein matrix reinforced with synthetic collagen in the design of vascular grafts. Biomaterials. 2010 Sep; 31(27):7175-82.
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Kim W, Thévenot J, Ibarboure E, Lecommandoux S, Chaikof EL. Self-assembly of thermally responsive amphiphilic diblock copolypeptides into spherical micellar nanoparticles. Angew Chem Int Ed Engl. 2010 Jun 7; 49(25):4257-60.
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Coady MA, Ikonomidis JS, Cheung AT, Matsumoto AH, Dake MD, Chaikof EL, Cambria RP, Mora-Mangano CT, Sundt TM, Sellke FW. Surgical management of descending thoracic aortic disease: open and endovascular approaches: a scientific statement from the American Heart Association. Circulation. 2010 Jun 29; 121(25):2780-804.
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Krishnamurthy VR, Wilson JT, Cui W, Song X, Lasanajak Y, Cummings RD, Chaikof EL. Chemoselective immobilization of peptides on abiotic and cell surfaces at controlled densities. Langmuir. 2010 Jun 1; 26(11):7675-8.
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Krishnamurthy VR, Dougherty A, Kamat M, Song X, Cummings RD, Chaikof EL. Synthesis of an Fmoc-threonine bearing core-2 glycan: a building block for PSGL-1 via Fmoc-assisted solid-phase peptide synthesis. Carbohydr Res. 2010 Jul 19; 345(11):1541-7.
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Caves JM, Kumar VA, Xu W, Naik N, Allen MG, Chaikof EL. Microcrimped collagen fiber-elastin composites. Adv Mater. 2010 May 11; 22(18):2041-4.
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Chaikof EL. Materials science: Muscle mimic. Nature. 2010 May 6; 465(7294):44-5.
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Kim W, Chaikof EL. Recombinant elastin-mimetic biomaterials: Emerging applications in medicine. Adv Drug Deliv Rev. 2010 Dec 30; 62(15):1468-78.
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Caves JM, Kumar VA, Wen J, Cui W, Martinez A, Apkarian R, Coats JE, Berland K, Chaikof EL. Fibrillogenesis in continuously spun synthetic collagen fiber. J Biomed Mater Res B Appl Biomater. 2010 Apr; 93(1):24-38.
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Hwang CK, Wang JY, Chaikof EL. Spontaneous dissection of the superior mesenteric artery. Ann Vasc Surg. 2010 Feb; 24(2):254.e1-5.
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Wilson JT, Haller CA, Qu Z, Cui W, Urlam MK, Chaikof EL. Biomolecular surface engineering of pancreatic islets with thrombomodulin. Acta Biomater. 2010 Jun; 6(6):1895-903.
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Ravi S, Chaikof EL. Biomaterials for vascular tissue engineering. Regen Med. 2010 Jan; 5(1):107-20.
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Wilson JT, Krishnamurthy VR, Cui W, Qu Z, Chaikof EL. Noncovalent cell surface engineering with cationic graft copolymers. J Am Chem Soc. 2009 Dec 30; 131(51):18228-9.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF. 2009 ACCF/AHA focused update on perioperative beta blockade incorporated into the ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery. J Am Coll Cardiol. 2009 Nov 24; 54(22):e13-e118.
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Dong H, Song X, Lasanajak Y, Cummings RD, Chaikof EL. Facile construction of fluorescent peptide microarrays: One-step fluorescent derivatization of sub-microscale peptide aldehydes for selective terminal immobilization. Anal Biochem. 2010 Mar 1; 398(1):132-4.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF. 2009 ACCF/AHA focused update on perioperative beta blockade incorporated into the ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American college of cardiology foundation/American heart association task force on practice guidelines. Circulation. 2009 Nov 24; 120(21):e169-276.
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Sallach RE, Conticello VP, Chaikof EL. Expression of a recombinant elastin-like protein in pichia pastoris. Biotechnol Prog. 2009 Nov-Dec; 25(6):1810-8.
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Sallach RE, Cui W, Balderrama F, Martinez AW, Wen J, Haller CA, Taylor JV, Wright ER, Long RC, Chaikof EL. Long-term biostability of self-assembling protein polymers in the absence of covalent crosslinking. Biomaterials. 2010 Feb; 31(4):779-91.
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Chaikof EL, Brewster DC, Dalman RL, Makaroun MS, Illig KA, Sicard GA, Timaran CH, Upchurch GR, Veith FJ. SVS practice guidelines for the care of patients with an abdominal aortic aneurysm: executive summary. J Vasc Surg. 2009 Oct; 50(4):880-96.
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Chaikof EL, Brewster DC, Dalman RL, Makaroun MS, Illig KA, Sicard GA, Timaran CH, Upchurch GR, Veith FJ. The care of patients with an abdominal aortic aneurysm: the Society for Vascular Surgery practice guidelines. J Vasc Surg. 2009 Oct; 50(4 Suppl):S2-49.
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Chaikof EL. Caring for patients with an abdominal aortic aneurysm: data, knowledge, and wisdom. J Vasc Surg. 2009 Oct; 50(4 Suppl):S1.
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Cui W, Wilson JT, Wen J, Angsana J, Qu Z, Haller CA, Chaikof EL. Thrombomodulin improves early outcomes after intraportal islet transplantation. Am J Transplant. 2009 Jun; 9(6):1308-16.
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Chaikof EL, Mutrie C, Kasirajan K, Milner R, Chen EP, Veeraswamy RK, Dodson TF, Salam AA. Endovascular repair for diverse pathologies of the thoracic aorta: an initial decade of experience. J Am Coll Surg. 2009 May; 208(5):802-16; discussion 816-8.
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Ravi S, Qu Z, Chaikof EL. Polymeric materials for tissue engineering of arterial substitutes. Vascular. 2009 May-Jun; 17 Suppl 1:S45-54.
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Deaton DH, Mehta M, Kasirajan K, Chaikof E, Farber M, Glickman MH, Neville RF, Fairman RM. The phase I multicenter trial (STAPLE-1) of the Aptus endovascular repair system: results at 6 months and 1 year. J Vasc Surg. 2009 Apr; 49(4):851-7; discussion 857-8.
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Sallach RE, Leisen J, Caves JM, Fotovich E, Apkarian RP, Conticello VP, Chaikof EL. A permanent change in protein mechanical responses can be produced by thermally-induced microdomain mixing. J Biomater Sci Polym Ed. 2009; 20(11):1629-44.
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Sun W, Chaikof EL, Levenston ME. Numerical approximation of tangent moduli for finite element implementations of nonlinear hyperelastic material models. J Biomech Eng. 2008 Dec; 130(6):061003.
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Sallach RE, Cui W, Wen J, Martinez A, Conticello VP, Chaikof EL. Elastin-mimetic protein polymers capable of physical and chemical crosslinking. Biomaterials. 2009 Jan; 30(3):409-22.
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Wilson JT, Chaikof EL. Thrombosis and inflammation in intraportal islet transplantation: a review of pathophysiology and emerging therapeutics. J Diabetes Sci Technol. 2008 Sep; 2(5):746-59.
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Feng X, Taton D, Ibarboure E, Chaikof EL, Gnanou Y. Janus-type dendrimer-like poly(ethylene oxide)s. J Am Chem Soc. 2008 Sep 3; 130(35):11662-76.
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Wu X, Sallach RE, Caves JM, Conticello VP, Chaikof EL. Deformation responses of a physically cross-linked high molecular weight elastin-like protein polymer. Biomacromolecules. 2008 Jul; 9(7):1787-94.
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Wilson JT, Cui W, Chaikof EL. Layer-by-layer assembly of a conformal nanothin PEG coating for intraportal islet transplantation. Nano Lett. 2008 Jul; 8(7):1940-8.
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Wang W, Haller CA, Wen J, Wang P, Chaikof EL. Decoupled syndecan 1 mRNA and protein expression is differentially regulated by angiotensin II in macrophages. J Cell Physiol. 2008 Mar; 214(3):750-6.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Anesth Analg. 2008 Mar; 106(3):685-712.
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Smith S, Mountcastle S, Burridge A, Dodson TF, Salam AA, Kasirajan K, Milner R, Veeraswamy R, Chaikof EL. A single-institution experience with the AneuRx Stent Graft for endovascular repair of abdominal aortic aneurysm. Ann Vasc Surg. 2008 Mar; 22(2):221-6.
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Rele S, Song Y, Apkarian RP, Qu Z, Conticello VP, Chaikof EL. D-periodic collagen-mimetic microfibers. J Am Chem Soc. 2007 Nov 28; 129(47):14780-7.
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Stabler CL, Sun XL, Cui W, Wilson JT, Haller CA, Chaikof EL. Surface re-engineering of pancreatic islets with recombinant azido-thrombomodulin. Bioconjug Chem. 2007 Nov-Dec; 18(6):1713-5.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW. ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) Developed in Collaboration With the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. J Am Coll Cardiol. 2007 Oct 23; 50(17):1707-32.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. J Am Coll Cardiol. 2007 Oct 23; 50(17):e159-241.
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Niessner A, Shin MS, Pryshchep O, Goronzy JJ, Chaikof EL, Weyand CM. Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque. Circulation. 2007 Oct 30; 116(18):2043-52.
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Wilson JT, Chaikof EL. Challenges and emerging technologies in the immunoisolation of cells and tissues. Adv Drug Deliv Rev. 2008 Jan 14; 60(2):124-45.
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Chaikof EL. The development of prosthetic heart valves--lessons in form and function. N Engl J Med. 2007 Oct 4; 357(14):1368-71.
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Wen J, Wang P, Smith SV, Haller CA, Chaikof EL. Syndecans are differentially expressed during the course of aortic aneurysm formation. J Vasc Surg. 2007 Nov; 46(5):1014-25.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW. ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): Developed in Collaboration With the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. Circulation. 2007 Oct 23; 116(17):1971-96.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Tarkington LG, Yancy CW. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. Circulation. 2007 Oct 23; 116(17):e418-99.
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Chaikof EL, Wang JY. Commentary on "Biological treatment of vein grafts and stents in lower-extremity arterial reconstruction". Perspect Vasc Surg Endovasc Ther. 2007 Sep; 19(3):298-9.
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Feng X, Taton D, Chaikof EL, Gnanou Y. Bouquet-type dendrimerlike poly(ethylene oxide)s with a focal aldehyde and peripheral hydroxyls. Biomacromolecules. 2007 Aug; 8(8):2374-8.
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Jordan SW, Chaikof EL. Novel thromboresistant materials. J Vasc Surg. 2007 Jun; 45 Suppl A:A104-15.
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Harris LM, Chaikof EL, Eidt JF. Altering the career choice: can we attract more women to vascular surgery? J Vasc Surg. 2007 Apr; 45(4):846-8.
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Julien MA, Haller CA, Wang P, Wen J, Chaikof EL. Mechanical strain induces a persistent upregulation of syndecan-1 expression in smooth muscle cells. J Cell Physiol. 2007 Apr; 211(1):167-73.
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Chaikof EL. Crossing boundaries. World J Surg. 2007 Apr; 31(4):619-20.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF. ACC/AHA 2006 guideline update on perioperative cardiovascular evaluation for noncardiac surgery: focused update on perioperative beta-blocker therapy--a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Anesth Analg. 2007 Jan; 104(1):15-26.
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Caves JM, Chaikof EL. The evolving impact of microfabrication and nanotechnology on stent design. J Vasc Surg. 2006 Dec; 44(6):1363-8.
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Niessner A, Sato K, Chaikof EL, Colmegna I, Goronzy JJ, Weyand CM. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation. 2006 Dec 5; 114(23):2482-9.
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Jordan SW, Haller CA, Sallach RE, Apkarian RP, Hanson SR, Chaikof EL. The effect of a recombinant elastin-mimetic coating of an ePTFE prosthesis on acute thrombogenicity in a baboon arteriovenous shunt. Biomaterials. 2007 Feb; 28(6):1191-7.
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Wilson JT, Cui W, Sun XL, Tucker-Burden C, Weber CJ, Chaikof EL. In vivo biocompatibility and stability of a substrate-supported polymerizable membrane-mimetic film. Biomaterials. 2007 Feb; 28(4):609-17.
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Sallach RE, Wei M, Biswas N, Conticello VP, Lecommandoux S, Dluhy RA, Chaikof EL. Micelle density regulated by a reversible switch of protein secondary structure. J Am Chem Soc. 2006 Sep 13; 128(36):12014-9.
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Feng X, Taton D, Borsali R, Chaikof EL, Gnanou Y. pH responsiveness of dendrimer-like poly(ethylene oxide)s. J Am Chem Soc. 2006 Sep 6; 128(35):11551-62.
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Julien MA, Wang P, Haller CA, Wen J, Chaikof EL. Mechanical strain regulates syndecan-4 expression and shedding in smooth muscle cells through differential activation of MAP kinase signaling pathways. Am J Physiol Cell Physiol. 2007 Jan; 292(1):C517-25.
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Wu X, Levenston ME, Chaikof EL. A constitutive model for protein-based materials. Biomaterials. 2006 Oct; 27(30):5315-25.
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ACC/AHA 2006 guideline update on perioperative cardiovascular evaluation for noncardiac surgery: focused update on perioperative beta-blocker therapy: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society for Vascular Medicine and Biology. J Am Coll Cardiol. 2006 Jun 6; 47(11):2343-55.
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Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Page RL, Riegel B. ACC/AHA 2006 guideline update on perioperative cardiovascular evaluation for noncardiac surgery: focused update on perioperative beta-blocker therapy: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society for Vascular Medicine and Biology. Circulation. 2006 Jun 6; 113(22):2662-74.
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Milner R, Kasirajan K, Chaikof EL. Future of endograft surveillance. Semin Vasc Surg. 2006 Jun; 19(2):75-82.
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Kasirajan K, Milner R, Chaikof EL. Combination therapies for deep venous thrombosis. Semin Vasc Surg. 2006 Jun; 19(2):116-21.
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Haller CA, Cui W, Wen J, Robson SC, Chaikof EL. Reconstitution of CD39 in liposomes amplifies nucleoside triphosphate diphosphohydrolase activity and restores thromboregulatory properties. J Vasc Surg. 2006 Apr; 43(4):816-23.
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Jordan SW, Faucher KM, Caves JM, Apkarian RP, Rele SS, Sun XL, Hanson SR, Chaikof EL. Fabrication of a phospholipid membrane-mimetic film on the luminal surface of an ePTFE vascular graft. Biomaterials. 2006 Jun; 27(18):3473-81.
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Kasirajan K, Milner R, Chaikof EL. Late complications of thoracic endografts. J Vasc Surg. 2006 Feb; 43 Suppl A:94A-99A.
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Milner R, Kasirajan K, Chaikof EL. Recommended clinical competencies for initiating a program in endovascular repair of the thoracic aorta. J Vasc Surg. 2006 Feb; 43 Suppl A:100A-105A.
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Sun XL, Biswas N, Kai T, Dai Z, Dluhy RA, Chaikof EL. Membrane-mimetic films of asymmetric phosphatidylcholine lipid bolaamphiphiles. Langmuir. 2006 Jan 31; 22(3):1201-8.
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Tseng PY, Rele SS, Sun XL, Chaikof EL. Membrane-mimetic films containing thrombomodulin and heparin inhibit tissue factor-induced thrombin generation in a flow model. Biomaterials. 2006 Apr; 27(12):2637-50.
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Sun XL, Stabler CL, Cazalis CS, Chaikof EL. Carbohydrate and protein immobilization onto solid surfaces by sequential Diels-Alder and azide-alkyne cycloadditions. Bioconjug Chem. 2006 Jan-Feb; 17(1):52-7.
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Burke RM, Rayan SS, Kasirajan K, Chaikof EL, Milner R. Unusual case of right-sided May-Thurner syndrome and review of its management. Vascular. 2006 Jan-Feb; 14(1):47-50.
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Tseng PY, Jordan SW, Sun XL, Chaikof EL. Catalytic efficiency of a thrombomodulin-functionalized membrane-mimetic film in a flow model. Biomaterials. 2006 May; 27(13):2768-75.
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Tseng PY, Rele SM, Sun XL, Chaikof EL. Fabrication and characterization of heparin functionalized membrane-mimetic assemblies. Biomaterials. 2006 Apr; 27(12):2627-36.
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Murphy MR, Faucher KM, Sun XL, Chaikof EL, Dluhy RA. Analysis of photoinitiated polymerization in a membrane mimetic film using infrared spectroscopy and near-IR Raman microscopy. Colloids Surf B Biointerfaces. 2005 Dec 30; 46(4):226-32.
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Wu X, Sallach R, Haller CA, Caves JA, Nagapudi K, Conticello VP, Levenston ME, Chaikof EL. Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks. Biomacromolecules. 2005 Nov-Dec; 6(6):3037-44.
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Sun XL, Haller CA, Wu X, Conticello VP, Chaikof EL. One-pot glyco-affinity precipitation purification for enhanced proteomics: the flexible alignment of solution-phase capture/release and solid-phase separation. J Proteome Res. 2005 Nov-Dec; 4(6):2355-9.
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Silverstein MD, Pitts SR, Chaikof EL, Ballard DJ. Abdominal aortic aneurysm (AAA): cost-effectiveness of screening, surveillance of intermediate-sized AAA, and management of symptomatic AAA. Proc (Bayl Univ Med Cent). 2005 Oct; 18(4):345-67.
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Kong LS, MacMillan D, Kasirajan K, Milner R, Dodson TF, Salam AA, Smith RB, Chaikof EL. Secondary conversion of the Gore Excluder to operative abdominal aortic aneurysm repair. J Vasc Surg. 2005 Oct; 42(4):631-8.
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Eidt JF, Chaikof E, Sidawy AN. Characteristics of the applicant pool to vascular surgery residency programs. J Vasc Surg. 2005 Sep; 42(3):519-23.
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Feng XS, Taton D, Chaikof EL, Gnanou Y. Toward an easy access to dendrimer-like poly(ethylene oxide)s. J Am Chem Soc. 2005 Aug 10; 127(31):10956-66.
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Nagapudi K, Brinkman WT, Thomas BS, Park JO, Srinivasarao M, Wright E, Conticello VP, Chaikof EL. Viscoelastic and mechanical behavior of recombinant protein elastomers. Biomaterials. 2005 Aug; 26(23):4695-706.
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Rele SM, Cui W, Wang L, Hou S, Barr-Zarse G, Tatton D, Gnanou Y, Esko JD, Chaikof EL. Dendrimer-like PEO glycopolymers exhibit anti-inflammatory properties. J Am Chem Soc. 2005 Jul 27; 127(29):10132-3.
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Dong CM, Wu X, Caves J, Rele SS, Thomas BS, Chaikof EL. Photomediated crosslinking of C6-cinnamate derivatized type I collagen. Biomaterials. 2005 Jun; 26(18):4041-9.
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Kai T, Sun XL, Faucher KM, Apkarian RP, Chaikof EL. Design and synthesis of asymmetric acyclic phospholipid bolaamphiphiles. J Org Chem. 2005 Apr 1; 70(7):2606-15.
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Makaroun MS, Dillavou ED, Kee ST, Sicard G, Chaikof E, Bavaria J, Williams D, Cambria RP, Mitchell RS. Endovascular treatment of thoracic aortic aneurysms: results of the phase II multicenter trial of the GORE TAG thoracic endoprosthesis. J Vasc Surg. 2005 Jan; 41(1):1-9.
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Rele SM, Iyer SS, Baskaran S, Chaikof EL. Design and synthesis of dimeric heparinoid mimetics. J Org Chem. 2004 Dec 24; 69(26):9159-70.
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Sun XL, Cui W, Haller C, Chaikof EL. Site-specific multivalent carbohydrate labeling of quantum dots and magnetic beads. Chembiochem. 2004 Nov 5; 5(11):1593-6.
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Houston M, Julien MA, Parthasarathy S, Chaikof EL. Oxidized linoleic acid regulates expression and shedding of syndecan-4. Am J Physiol Cell Physiol. 2005 Feb; 288(2):C458-66.
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Cazalis CS, Haller CA, Sease-Cargo L, Chaikof EL. C-terminal site-specific PEGylation of a truncated thrombomodulin mutant with retention of full bioactivity. Bioconjug Chem. 2004 Sep-Oct; 15(5):1005-9.
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Hou S, Sun XL, Dong CM, Chaikof EL. Facile synthesis of chain-end functionalized glycopolymers for site-specific bioconjugation. Bioconjug Chem. 2004 Sep-Oct; 15(5):954-9.
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Rayan SS, Vega JD, Shanewise JS, Kong LS, Chaikof EL, Milner R. Repair of mycotic aortic pseudoaneurysm with a stent graft using transesophageal echocardiography. J Vasc Surg. 2004 Sep; 40(3):567-70.
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Brinkman WT, Terramani TT, Najibi S, Weiss VJ, Salam AA, Dodson TF, Smith RB, Chaikof EL. Endovascular abdominal aortic aneurysm repair in the octogenarian. Ann Vasc Surg. 2004 Jul; 18(4):401-7.
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Cui W, Barr G, Faucher KM, Sun XL, Safley SA, Weber CJ, Chaikof EL. A membrane-mimetic barrier for islet encapsulation. Transplant Proc. 2004 May; 36(4):1206-8.
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Guan R, Sun XL, Hou S, Wu P, Chaikof EL. A glycopolymer chaperone for fibroblast growth factor-2. Bioconjug Chem. 2004 Jan-Feb; 15(1):145-51.
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Dong CM, Sun XL, Faucher KM, Apkarian RP, Chaikof EL. Synthesis and characterization of glycopolymer-polypeptide triblock copolymers. Biomacromolecules. 2004 Jan-Feb; 5(1):224-31.
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Rayan SS, Terramani TT, Weiss VJ, Chaikof EL. The LifeSite Hemodialysis Access System in patients with limited access. J Vasc Surg. 2003 Oct; 38(4):714-8.
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Terramani TT, Chaikof EL, Rayan SS, Lin PH, Najibi S, Bush RL, Lumsden AB, Salam A, Smith RB, Dodson TF. Secondary conversion due to failed endovascular abdominal aortic aneurysm repair. J Vasc Surg. 2003 Sep; 38(3):473-7; discussion 477-8.
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Lin PH, Bush RL, Milas M, Terramani TT, Dodson TF, Chen C, Chaikof EL, Lumsden AB. Impact of an endovascular program on the operative experience of abdominal aortic aneurysm in vascular fellowship and general surgery residency. Am J Surg. 2003 Aug; 186(2):189-93.
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Iyer S, Rele S, Grasa G, Nolan S, Chaikof EL. Synthesis of a hyaluronan neoglycopolymer by ring-opening metathesis polymerization. Chem Commun (Camb). 2003 Jul 7; (13):1518-9.
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Brinkman WT, Nagapudi K, Thomas BS, Chaikof EL. Photo-cross-linking of type I collagen gels in the presence of smooth muscle cells: mechanical properties, cell viability, and function. Biomacromolecules. 2003 Jul-Aug; 4(4):890-5.
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Brinkman WT, Terramani TT, Najibi S, Chaikof EL. Platelets: is aspirin sufficient or must we know how to pronounce abciximab? Semin Vasc Surg. 2002 Dec; 15(4):245-55.
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Li L, Chaikof EL. Quantitative nuclear run-off transcription assay. Biotechniques. 2002 Nov; 33(5):1016-7.
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Baskaran S, Grande D, Sun XL, Yayon A, Chaikof EL. Glycosaminoglycan-mimetic biomaterials. 3. Glycopolymers prepared from alkene-derivatized mono- and disaccharide-based glycomonomers. Bioconjug Chem. 2002 Nov-Dec; 13(6):1309-13.
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Najibi S, Terramani TT, Weiss VJ, Mac Donald MJ, Lin PH, Redd DC, Martin LG, Chaikof EL, Lumsden AB. Endoluminal versus open treatment of descending thoracic aortic aneurysms. J Vasc Surg. 2002 Oct; 36(4):732-7.
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Sun XL, Grande D, Baskaran S, Hanson SR, Chaikof EL. Glycosaminoglycan mimetic biomaterials. 4. Synthesis of sulfated lactose-based glycopolymers that exhibit anticoagulant activity. Biomacromolecules. 2002 Sep-Oct; 3(5):1065-70.
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Lin PH, Bush RL, Chaikof EL, Chen C, Conklin B, Terramani TT, Brinkman WT, Lumsden AB. A prospective evaluation of hypogastric artery embolization in endovascular aortoiliac aneurysm repair. J Vasc Surg. 2002 Sep; 36(3):500-6.
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Li L, Couse TL, Deleon H, Xu CP, Wilcox JN, Chaikof EL. Regulation of syndecan-4 expression with mechanical stress during the development of angioplasty-induced intimal thickening. J Vasc Surg. 2002 Aug; 36(2):361-70.
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Chaikof EL. Capturing an accurate measure of success-outcomes and endpoints in endovascular aneurysm repair. J Vasc Surg. 2002 Aug; 36(2):410-1.
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Baxter BT, Pearce WH, Waltke EA, Littooy FN, Hallett JW, Kent KC, Upchurch GR, Chaikof EL, Mills JL, Fleckten B, Longo GM, Lee JK, Thompson RW. Prolonged administration of doxycycline in patients with small asymptomatic abdominal aortic aneurysms: report of a prospective (Phase II) multicenter study. J Vasc Surg. 2002 Jul; 36(1):1-12.
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Najibi S, Bush RL, Terramani TT, Chaikof EL, Gunnoud AB, Lumsden AB, Weiss VJ. Covered stent exclusion of dialysis access pseudoaneurysms. J Surg Res. 2002 Jul; 106(1):15-9.
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Sun XL, Faucher KM, Houston M, Grande D, Chaikof EL. Design and synthesis of biotin chain-terminated glycopolymers for surface glycoengineering. J Am Chem Soc. 2002 Jun 26; 124(25):7258-9.
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Chaikof EL, Matthew H, Kohn J, Mikos AG, Prestwich GD, Yip CM. Biomaterials and scaffolds in reparative medicine. Ann N Y Acad Sci. 2002 Jun; 961:96-105.
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Chaikof EL. Hear no evil, see no evil, speak no evil: postmarket monitoring, underreporting, and estimating the prevalence of endograft-related adverse events. J Vasc Surg. 2002 Jun; 35(6):1299-300.
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Chaikof EL, Lin PH, Brinkman WT, Dodson TF, Weiss VJ, Lumsden AB, Terramani TT, Najibi S, Bush RL, Salam AA, Smith RB. Endovascular repair of abdominal aortic aneurysms: risk stratified outcomes. Ann Surg. 2002 Jun; 235(6):833-41.
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Chaikof E, Matthew H, Kohn J, Prestwich GD, Mikos A, Yip C. Bioscaffolds for tissue repair: breakout session summary. Ann N Y Acad Sci. 2002 Jun; 961:112-3.
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Chaikof EL, Fillinger MF, Matsumura JS, Rutherford RB, White GH, Blankensteijn JD, Bernhard VM, Harris PL, Kent KC, May J, Veith FJ, Zarins CK. Identifying and grading factors that modify the outcome of endovascular aortic aneurysm repair. J Vasc Surg. 2002 May; 35(5):1061-6.
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Chaikof EL, Blankensteijn JD, Harris PL, White GH, Zarins CK, Bernhard VM, Matsumura JS, May J, Veith FJ, Fillinger MF, Rutherford RB, Kent KC. Reporting standards for endovascular aortic aneurysm repair. J Vasc Surg. 2002 May; 35(5):1048-60.
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Lin PH, Bush RL, Conklin BS, Chen C, Weiss VJ, Chaikof EL, Lumsden AB. Late complication of aortoiliac stent placement- atheroembolization of the lower extremities. J Surg Res. 2002 Apr; 103(2):153-9.
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Lin PH, Bush RL, Conklin BS, Chaikof EL, Lumsden AB. Percutaneous bedside femorofemoral bypass grafting for acute limb ischemia caused by intra-aortic balloon pump. J Vasc Surg. 2002 Mar; 35(3):592-4.
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Najibi S, Terramani TT, Weiss VJ, Smith RB, Salam AA, Dodson TF, Chaikof EL, Lumsden AB. Endovascular aortic aneurysm operations. Arch Surg. 2002 Feb; 137(2):211-6.
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Makaroun MS, Chaikof E, Naslund T, Matsumura JS. Efficacy of a bifurcated endograft versus open repair of abdominal aortic aneurysms: a reappraisal. J Vasc Surg. 2002 Feb; 35(2):203-10.
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Chon JH, Chaikof EL. A von Willebrand factor-derived heparin-binding peptide regulates cell--substrate adhesive strength and chemokinesis behavior. Biochim Biophys Acta. 2002 Jan 30; 1542(1-3):195-208.
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Li L, Chaikof EL. Mechanical stress regulates syndecan-4 expression and redistribution in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2002 Jan; 22(1):61-8.
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Bush RL, Najibi S, Lin PH, Lumsden AB, Dodson TF, Salam AA, Smith RB, Chaikof EL, Weiss VL. Conservatism and new technology: the impact on abdominal aortic aneurysm repair. Am Surg. 2002 Jan; 68(1):57-60; discussion 60-1.
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Lin PH, Dodson TF, Bush RL, Weiss VJ, Conklin BS, Chen C, Chaikof EL, Lumsden AB. Surgical intervention for complications caused by femoral artery catheterization in pediatric patients. J Vasc Surg. 2001 Dec; 34(6):1071-8.
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Lin PH, Bush RL, Tong FC, Chaikof E, Martin LG, Lumsden AB. Intra-arterial thrombin injection of an ascending aortic pseudoaneurysm complicated by transient ischemic attack and rescued with systemic abciximab. J Vasc Surg. 2001 Nov; 34(5):939-42.
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Chon JH, Houston MM, Xu C, Chaikof EL. PR-39 coordinates changes in vascular smooth muscle cell adhesive strength and locomotion by modulating cell surface heparan sulfate-matrix interactions. J Cell Physiol. 2001 Nov; 189(2):133-43.
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Huang L, Apkarian RP, Chaikof EL. High-resolution analysis of engineered type I collagen nanofibers by electron microscopy. Scanning. 2001 Nov-Dec; 23(6):372-5.
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Bush RL, Najibi S, Lin PH, Weiss VJ, MacDonald MJ, Redd DC, Martin LG, Chaikof EL, Lumsden AB. Early experience with the bifurcated Excluder endoprosthesis for treatment of the abdominal aortic aneurysm. J Vasc Surg. 2001 Sep; 34(3):497-502.
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Sun XL, Liu H, Orban JM, Sun L, Chaikof EL. Synthesis and terminal functionalization of a polymerizable phosphatidylethanolamine. Bioconjug Chem. 2001 Sep-Oct; 12(5):673-7.
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Najibi S, Steinberg J, Katzen BT, Zemel G, Lin PH, Weiss VJ, Lumsden AB, Chaikof EL. Detection of isolated hook fractures 36 months after implantation of the Ancure endograft: a cautionary note. J Vasc Surg. 2001 Aug; 34(2):353-6.
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Chon JH, Chaikof EL. Soluble heparin-binding peptides regulate chemokinesis and cell adhesive forces. Am J Physiol Cell Physiol. 2001 Jun; 280(6):C1394-402.
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Bush RL, Najibi S, MacDonald MJ, Lin PH, Chaikof EL, Martin LG, Lumsden AB. Endovascular revascularization of renal artery stenosis: technical and clinical results. J Vasc Surg. 2001 May; 33(5):1041-9.
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Bush RL, Lumsden AB, Dodson TF, Salam AA, Weiss VJ, Smith RB, Chaikof EL. Mid-term results after endovascular repair of the abdominal aortic aneurysm. J Vasc Surg. 2001 Feb; 33(2 Suppl):S70-6.
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Berry AJ, Smith RB, Weintraub WS, Chaikof EL, Dodson TF, Lumsden AB, Salam AA, Weiss V, Konigsberg S. Age versus comorbidities as risk factors for complications after elective abdominal aortic reconstructive surgery. J Vasc Surg. 2001 Feb; 33(2):345-52.
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Bush RL, Martin LG, Lin PH, MacDonald MJ, Chaikof EL, Lumsden AB, Weiss VJ. Endovascular revascularization of renal artery stenosis in the solitary functioning kidney. Ann Vasc Surg. 2001 Jan; 15(1):60-6.
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Huang L, Nagapudi K, Apkarian RP, Chaikof EL. Engineered collagen-PEO nanofibers and fabrics. J Biomater Sci Polym Ed. 2001; 12(9):979-93.
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Lin PH, Surowiec SM, Conklin B, Bush RL, Chen C, Chaikof EL, Lumsden AB. An endovascular model of carotid stenosis for the evaluation of thrombolysis and angioplasty. J Endovasc Ther. 2000 Dec; 7(6):486-93.
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Lin PH, Bush RL, Weiss VJ, Dodson TF, Chaikof EL, Lumsden AB. Subclavian artery disruption resulting from endovascular intervention: treatment options. J Vasc Surg. 2000 Sep; 32(3):607-11.
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Lin PH, Chen C, Surowiec SM, Conklin B, Bush RL, Chaikof EL, Lumsden AB, Weiss V. A porcine model of carotid artery thrombosis for thrombolytic therapy and angioplasty: application of PTFE graft-induced stenosis. J Endovasc Ther. 2000 Jun; 7(3):227-35.
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Lin PH, Chaikof EL. Embryology, anatomy, and surgical exposure of the great abdominal vessels. Surg Clin North Am. 2000 Feb; 80(1):417-33, xiv.
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Matsumura JS, Chaikof EL. Anatomic changes after endovascular grafting for aneurysmal disease. Semin Vasc Surg. 1999 Sep; 12(3):192-8.
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Chaikof EL, Matsumura JS. Endovascular repair of abdominal aortic aneurysms: problems and progress. Semin Vasc Surg. 1999 Sep; 12(3):163-4.
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Chaikof EL. Developing a discriminant noninvasive test for early mesenteric ischemia: measuring the basic rhythms of life. J Vasc Surg. 1999 Aug; 30(2):367-9.
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Weiss VJ, Chaikof EL. Endovascular treatment of vascular injuries. Surg Clin North Am. 1999 Jun; 79(3):653-65.
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Chaikof EL. Engineering and material considerations in islet cell transplantation. Annu Rev Biomed Eng. 1999; 1:103-27.
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Chon JH, Marra KG, Chaikof EL. Cytomimetic biomaterials. 3. Preparation and transport studies of an alginate/amphiphilic copolymer/polymerized phospholipid film. J Biomater Sci Polym Ed. 1999; 10(1):95-107.
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Chon JH, Netzel R, Rock BM, Chaikof EL. Alpha4beta1 and alpha5beta1 control cell migration on fibronectin by differentially regulating cell speed and motile cell phenotype. Ann Biomed Eng. 1998 Nov-Dec; 26(6):1091-101.
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Matsumura JS, Chaikof EL. Continued expansion of aortic necks after endovascular repair of abdominal aortic aneurysms. EVT Investigators. EndoVascular Technologies, Inc. J Vasc Surg. 1998 Sep; 28(3):422-30; discussion 430-1.
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Kulbaski MJ, Kosinski AS, Smith RB, Salam AA, Dodson TF, Lumsden AB, Chaikof EL. Concomitant aortic and renal artery reconstruction in patients on an intensive antihypertensive medical regimen: long-term outcome. Ann Vasc Surg. 1998 May; 12(3):270-7.
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Sun L, Chaikof EL. The synthesis of neoglycophospholipid conjugates via reductive amination of omega-oxoalkylglycosides and phosphatidylethanolamines. Carbohydr Res. 1998 Feb; 307(1-2):77-81.
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Chon JH, Vizena AD, Rock BM, Chaikof EL. Characterization of single-cell migration using a computer-aided fluorescence time-lapse videomicroscopy system. Anal Biochem. 1997 Oct 15; 252(2):246-54.
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Chon JH, Wang HS, Chaikof EL. Role of fibronectin and sulfated proteoglycans in endothelial cell migration on a cultured smooth muscle layer. J Surg Res. 1997 Sep; 72(1):53-9.
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Sun L, Chaikof EL. Neoglycophospholipids with alkyl spacers: synthesis via an improved reductive amination and monolayer properties. Bioconjug Chem. 1997 Jul-Aug; 8(4):567-71.
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Wang HS, Li F, Runge MS, Chaikof EL. Endothelial cells exhibit differential chemokinetic and mitogenic responsiveness to alpha-thrombin. J Surg Res. 1997 Mar; 68(2):139-44.
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Chaikof EL. Revascularization of the occluded renal artery. Semin Vasc Surg. 1996 Sep; 9(3):218-20.
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Chaikof EL, Smith RB, Salam AA, Dodson TF, Lumsden AB, Chapman R, Kosinski AS. Empirical reconstruction of the renal artery: long-term outcome. J Vasc Surg. 1996 Sep; 24(3):406-14.
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Chaikof EL, Smith RB. Surgical management of occlusive disease of the common carotid artery. Semin Vasc Surg. 1996 Jun; 9(2):111-7.
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Coyle KA, Smith RB, Salam AA, Dodson TF, Chaikof EL, Lumsden AB. Carotid endarterectomy in patients with contralateral carotid occlusion: review of a 10-year experience. Cardiovasc Surg. 1996 Feb; 4(1):71-5.
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Winger TM, Ludovice PJ, Chaikof EL. Lipopeptide conjugates: biomolecular building blocks for receptor activating membrane-mimetic structures. Biomaterials. 1996 Feb; 17(4):437-41.
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Coyle KA, Smith RB, Chapman RL, Salam AA, Dodson TF, Lumsden AB, Chaikof EL. Carotid artery shortening: a safe adjunct to carotid endarterectomy. J Vasc Surg. 1995 Sep; 22(3):257-61; discussion 261-3.
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Lumsden AB, Allen RC, Chaikof EL, Resnikoff M, Moritz MW, Gerhard H, Castronuovo JJ. Delayed rupture of aortic aneurysms following endovascular stent grafting. Am J Surg. 1995 Aug; 170(2):174-8.
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Hughes JD, Bacha EA, Dodson TF, Martin T, Smith RB, Chaikof EL. Peripheral vascular complications of aortic dissection. Am J Surg. 1995 Aug; 170(2):209-12.
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Jordan WD, Smith RB, Salam AA, Dodson TF, Lumsden AB, Bacha EA, Chaikof EL. The occluded renal artery: an ongoing surgical challenge. Ann Vasc Surg. 1995 Jul; 9(4):344-51.
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Winger TM, Ludovice PJ, Chaikof EL. A convenient route to thiol terminated peptides for conjugation and surface functionalization strategies. Bioconjug Chem. 1995 May-Jun; 6(3):323-6.
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Coyle KA, Smith RB, Gray BC, Salam AA, Dodson TF, Chaikof EL, Lumsden AB. Treatment of recurrent cerebrovascular disease. Review of a 10-year experience. Ann Surg. 1995 May; 221(5):517-21; discussion 521-4.
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Chaikof EL, Caban R, Yan CN, Rao GN, Runge MS. Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences. J Biol Chem. 1995 Mar 31; 270(13):7431-6.
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Coyle KA, Gray BC, Smith RB, Salam AA, Dodson TF, Chaikof EL, Lumsden AB. Morbidity and mortality associated with carotid endarterectomy: effect of adjunctive coronary revascularization. Ann Vasc Surg. 1995 Jan; 9(1):21-7.
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Chaikof EL, Campbell BE, Smith RB. Paradoxical embolism and acute arterial occlusion: rare or unsuspected? J Vasc Surg. 1994 Sep; 20(3):377-84.
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Coyle KA, Smith RB, Salam AA, Dodson TF, Chaikof EL, Lumsden AB. Carotid endarterectomy in the octogenarian. Ann Vasc Surg. 1994 Sep; 8(5):417-20.
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Chaikof EL. Thoracoabdominal aneurysms: recognition, management, and remaining challenges. Heart Dis Stroke. 1994 May-Jun; 3(3):139-42.
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Chaikof EL, Smith RB, Salam AA, Dodson TF, Lumsden AB, Kosinski AS, Coyle KA, Allen RC. Ischemic nephropathy and concomitant aortic disease: a ten-year experience. J Vasc Surg. 1994 Jan; 19(1):135-46; discussion 146-8.
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Chaikof EL, Dodson TF, Thomas BL, Smith RB. Four steps to local anesthesia for endarterectomy of the carotid artery. Surg Gynecol Obstet. 1993 Sep; 177(3):308-10.
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Salam AA, Sholkamy SM, Chaikof EL. Spinal cord ischemia after abdominal aortic procedures: is previous colectomy a risk factor? J Vasc Surg. 1993 Jun; 17(6):1108-10.
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Chaikof EL, Merrill EW, Callow AD, Connolly RJ, Verdon SL, Ramberg K. PEO enhancement of platelet deposition, fibrinogen deposition, and complement C3 activation. J Biomed Mater Res. 1992 Sep; 26(9):1163-8.
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Chaikof EL, Dodson TF, Salam AA, Lumsden AB, Smith RB. Acute arterial thrombosis in the very young. J Vasc Surg. 1992 Sep; 16(3):428-35.
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Verdon SL, Chaikof EL, Coleman JE, Hayes LL, Connolly RJ, Ramberg K, Merrill EW, Callow AD. Scanning electron microscopy analysis of polyethylene oxide hydrogels for blood contact. Scanning Microsc. 1990 Jun; 4(2):341-9; discussion 349-50.
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Chaikof EL, Coleman JE, Ramberg K, Connolly RJ, Merrill EW, Callow AD. Development and evaluation of a new polymeric material for small caliber vascular prostheses. J Surg Res. 1989 Sep; 47(3):193-9.
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Chaikof EL. Nontraumatic perforation of the small bowel. Am J Surg. 1987 Apr; 153(4):355-8.
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Chaikof EL, Cambria RP, Warshaw AL. Colouterine fistula secondary to diverticulitis. Dis Colon Rectum. 1985 May; 28(5):358-60.
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Chaikof EL, McCabe CJ. Fatal overwhelming postsplenectomy infection. Am J Surg. 1985 Apr; 149(4):534-9.
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Chaikof EL, Shamberger RC, Brewster DC. Traumatic pseudoaneurysms of the abdominal aorta. J Trauma. 1985 Feb; 25(2):169-73.
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Chaikof EL, Goodson JD, McCabe CJ. Postsplenectomy pneumococcemia in a healthy vaccinated adult. Am J Emerg Med. 1984 Mar; 2(2):141-3.
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Donnenberg AD, Chaikof E, Aurelian L. Immunity to herpes simplex virus type 2: cell-mediated immunity in latently infected guinea pigs. Infect Immun. 1980 Oct; 30(1):99-109.
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