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Jian-Ping Xiong, PH.D.

TitleAssistant Professor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Renal Unit - Rm 8000
149 13th Street
Charlestown MA 02129
Phone617/726-5670
Fax617/726-5669

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Mahalingam B, Ajroud K, Alonso JL, Anand S, Adair BD, Horenstein AL, Malavasi F, Xiong JP, Arnaout MA. Stable coordination of the inhibitory Ca2+ ion at the metal ion-dependent adhesion site in integrin CD11b/CD18 by an antibody-derived ligand aspartate: implications for integrin regulation and structure-based drug design. J Immunol. 2011 Dec 15; 187(12):6393-401.
    View in: PubMed
  2. Xiong JP, Mahalingham B, Alonso JL, Borrelli LA, Rui X, Anand S, Hyman BT, Rysiok T, Müller-Pompalla D, Goodman SL, Arnaout MA. Crystal structure of the complete integrin alphaVbeta3 ectodomain plus an alpha/beta transmembrane fragment. J Cell Biol. 2009 Aug 24; 186(4):589-600.
    View in: PubMed
  3. Gupta V, Alonso JL, Sugimori T, Essafi M, Issafi M, Xiong JP, Arnaout MA. Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function. J Immunol. 2008 Feb 1; 180(3):1713-8.
    View in: PubMed
  4. Arnaout MA, Goodman SL, Xiong JP. Structure and mechanics of integrin-based cell adhesion. Curr Opin Cell Biol. 2007 Oct; 19(5):495-507.
    View in: PubMed
  5. Xiong JP, Goodman SL, Arnaout MA. Purification, analysis, and crystal structure of integrins. Methods Enzymol. 2007; 426:307-36.
    View in: PubMed
  6. Gupta V, Gylling A, Alonso JL, Sugimori T, Ianakiev P, Xiong JP, Arnaout MA. The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18. Blood. 2007 Apr 15; 109(8):3513-20.
    View in: PubMed
  7. Ding Z, Bradley KA, Amin Arnaout M, Xiong JP. Expression and purification of functional human anthrax toxin receptor (ATR/TEM8) binding domain from Escherichia coli. Protein Expr Purif. 2006 Sep; 49(1):121-8.
    View in: PubMed
  8. Ajroud K, Sugimori T, Goldmann WH, Fathallah DM, Xiong JP, Arnaout MA. Binding Affinity of Metal Ions to the CD11b A-domain Is Regulated by Integrin Activation and Ligands. J Biol Chem. 2004 Jun 11; 279(24):25483-8.
    View in: PubMed
  9. Xiong JP, Stehle T, Goodman SL, Arnaout MA. New insights into the structural basis of integrin activation. Blood. 2003 Aug 15; 102(4):1155-9.
    View in: PubMed
  10. Arnaout MA, Goodman SL, Xiong JP. Coming to grips with integrin binding to ligands. Curr Opin Cell Biol. 2002 Oct; 14(5):641-51.
    View in: PubMed
  11. Xiong JP, Stehle T, Zhang R, Joachimiak A, Frech M, Goodman SL, Arnaout MA. Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science. 2002 Apr 5; 296(5565):151-5.
    View in: PubMed
  12. Li R, Haruta I, Rieu P, Sugimori T, Xiong JP, Arnaout MA. Characterization of a conformationally sensitive murine monoclonal antibody directed to the metal ion-dependent adhesion site face of integrin CD11b. J Immunol. 2002 Feb 1; 168(3):1219-25.
    View in: PubMed
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