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Last Name
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Daniel J Gottlieb, M.D.

TitleLecturer on Medicine
InstitutionVeterans Affairs Boston Healthcare System
DepartmentMedicine
AddressBoston Va Med Ctr-W Roxbury
Medical Service (111)
1400 VFW Pkwy
West Roxbury MA 02132
Phone857/203-6375
Fax857/203-5670

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Fata B, Carruthers CA, Gibson G, Watkins SC, Gottlieb D, Mayer JE, Sacks MS. Regional structural and biomechanical alterations of the ovine main pulmonary artery during postnatal growth. J Biomech Eng. 2013 Feb; 135(2):021022.
    View in: PubMed
  2. Kushida CA, Nichols DA, Holmes TH, Quan SF, Walsh JK, Gottlieb DJ, Simon RD, Guilleminault C, White DP, Goodwin JL, Schweitzer PK, Leary EB, Hyde PR, Hirshkowitz M, Green S, McEvoy LK, Chan C, Gevins A, Kay GG, Bloch DA, Crabtree T, Dement WC. Effects of Continuous Positive Airway Pressure on Neurocognitive Function in Obstructive Sleep Apnea Patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep. 2012; 35(12):1593-602.
    View in: PubMed
  3. Patel SR, Goodloe R, De G, Kowgier M, Weng J, Buxbaum SG, Cade B, Fulop T, Gharib SA, Gottlieb DJ, Hillman D, Larkin EK, Lauderdale DS, Li L, Mukherjee S, Palmer L, Zee P, Zhu X, Redline S. Association of Genetic Loci with Sleep Apnea in European Americans and African-Americans: The Candidate Gene Association Resource (CARe). PLoS One. 2012; 7(11):e48836.
    View in: PubMed
  4. Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Ward SL, Tangredi MM. Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events: Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 2012; 8(5):597-619.
    View in: PubMed
  5. Chami HA, Baldwin CM, Silverman A, Zhang Y, Rapoport DM, Punjabi N, Gottlieb DJ. Erratum: Sleepiness, quality of life, and sleep maintenance in REM versus NREM sleep-disordered breathing. Am J Respir Crit Care Med. 2011 Sep 1; 184(5):622.
    View in: PubMed
  6. Sparrow D, Gottlieb DJ, Demolles D, Fielding RA. Increases in muscle strength and balance using a resistance training program administered via a telecommunications system in older adults. J Gerontol A Biol Sci Med Sci. 2011 Nov; 66(11):1251-7.
    View in: PubMed
  7. Chami HA, Resnick HE, Quan SF, Gottlieb DJ. Association of incident cardiovascular disease with progression of sleep-disordered breathing. Circulation. 2011 Mar 29; 123(12):1280-6.
    View in: PubMed
  8. Quan SF, Chan CS, Dement WC, Gevins A, Goodwin JL, Gottlieb DJ, Green S, Guilleminault C, Hirshkowitz M, Hyde PR, Kay GG, Leary EB, Nichols DA, Schweitzer PK, Simon RD, Walsh JK, Kushida CA. The association between obstructive sleep apnea and neurocognitive performance--the Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep. 2011 Mar; 34(3):303-314B.
    View in: PubMed
  9. Howland J, Rohsenow DJ, Arnedt JT, Bliss CA, Hunt SK, Calise TV, Heeren T, Winter M, Littlefield C, Gottlieb DJ. The acute effects of caffeinated versus non-caffeinated alcoholic beverage on driving performance and attention/reaction time. Addiction. 2011 Feb; 106(2):335-41.
    View in: PubMed
  10. Sparrow D, Aloia M, Demolles DA, Gottlieb DJ. A telemedicine intervention to improve adherence to continuous positive airway pressure: a randomised controlled trial. Thorax. 2010 Dec; 65(12):1061-6.
    View in: PubMed
  11. Eckert CE, Mikulis BT, Gottlieb D, Gerneke D, LeGrice I, Padera RF, Mayer JE, Schoen FJ, Sacks MS. Three-dimensional quantitative micromorphology of pre- and post-implanted engineered heart valve tissues. Ann Biomed Eng. 2011 Jan; 39(1):205-22.
    View in: PubMed
  12. Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer JE, Aikawa E. Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study. Tissue Eng Part C Methods. 2010 Aug; 16(4):597-607.
    View in: PubMed
  13. Gottlieb DJ, Yenokyan G, Newman AB, O'Connor GT, Punjabi NM, Quan SF, Redline S, Resnick HE, Tong EK, Diener-West M, Shahar E. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation. 2010 Jul 27; 122(4):352-60.
    View in: PubMed
  14. Weeks WB, Gottlieb DJ, Nyweide DE, Sutherland JM, Bynum J, Casalino LP, Gillies RR, Shortell SM, Fisher ES. Higher health care quality and bigger savings found at large multispecialty medical groups. Health Aff (Millwood). 2010 May; 29(5):991-7.
    View in: PubMed
  15. Redline S, Yenokyan G, Gottlieb DJ, Shahar E, O'Connor GT, Resnick HE, Diener-West M, Sanders MH, Wolf PA, Geraghty EM, Ali T, Lebowitz M, Punjabi NM. Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study. Am J Respir Crit Care Med. 2010 Jul 15; 182(2):269-77.
    View in: PubMed
  16. Gottlieb D, Kunal T, Emani S, Aikawa E, Brown DW, Powell AJ, Nedder A, Engelmayr GC, Melero-Martin JM, Sacks MS, Mayer JE. In vivo monitoring of function of autologous engineered pulmonary valve. J Thorac Cardiovasc Surg. 2010 Mar; 139(3):723-31.
    View in: PubMed
  17. Gottlieb DJ, Zhou W, Song Y, Andrews KG, Skinner JS, Sutherland JM. Prices don't drive regional Medicare spending variations. Health Aff (Millwood). 2010 Mar-Apr; 29(3):537-43.
    View in: PubMed
  18. Chami HA, Baldwin CM, Silverman A, Zhang Y, Rapoport D, Punjabi NM, Gottlieb DJ. Sleepiness, quality of life, and sleep maintenance in REM versus non-REM sleep-disordered breathing. Am J Respir Crit Care Med. 2010 May 1; 181(9):997-1002.
    View in: PubMed
  19. Nyweide DJ, Weeks WB, Gottlieb DJ, Casalino LP, Fisher ES. Relationship of primary care physicians' patient caseload with measurement of quality and cost performance. JAMA. 2009 Dec 9; 302(22):2444-50.
    View in: PubMed
  20. Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS. The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells. Biomaterials. 2010 Feb; 31(6):1114-25.
    View in: PubMed
  21. Chami HA, Keyes MJ, Vita JA, Mitchell GF, Larson MG, Fan S, Vasan RS, O'Connor GT, Benjamin EJ, Gottlieb DJ. Brachial artery diameter, blood flow and flow-mediated dilation in sleep-disordered breathing. Vasc Med. 2009 Nov; 14(4):351-60.
    View in: PubMed
  22. Punjabi NM, Caffo BS, Goodwin JL, Gottlieb DJ, Newman AB, O'Connor GT, Rapoport DM, Redline S, Resnick HE, Robbins JA, Shahar E, Unruh ML, Samet JM. Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med. 2009 Aug; 6(8):e1000132.
    View in: PubMed
  23. Thomas RJ, Weiss MD, Mietus JE, Peng CK, Goldberger AL, Gottlieb DJ. Prevalent hypertension and stroke in the Sleep Heart Health Study: association with an ECG-derived spectrographic marker of cardiopulmonary coupling. Sleep. 2009 Jul; 32(7):897-904.
    View in: PubMed
  24. Gottlieb DJ, Young TB. Natural history of sleep-disordered breathing: shedding light on the early years. Commentary on Bixler et al. Sleep disordered breathing in children in a general population sample: prevalence and risk factors. Sleep 2009;32(6):731-736. Sleep. 2009 Jun; 32(6):715-6.
    View in: PubMed
  25. Winkelman JW, Redline S, Baldwin CM, Resnick HE, Newman AB, Gottlieb DJ. Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health Study. Sleep. 2009 Jun; 32(6):772-8.
    View in: PubMed
  26. Anthony DL, Herndon MB, Gallagher PM, Barnato AE, Bynum JP, Gottlieb DJ, Fisher ES, Skinner JS. How much do patients' preferences contribute to resource use? Health Aff (Millwood). 2009 May-Jun; 28(3):864-73.
    View in: PubMed
  27. Wilk JB, Chen TH, Gottlieb DJ, Walter RE, Nagle MW, Brandler BJ, Myers RH, Borecki IB, Silverman EK, Weiss ST, O'Connor GT. A genome-wide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genet. 2009 Mar; 5(3):e1000429.
    View in: PubMed
  28. Robertson DJ, Stukel TA, Gottlieb DJ, Sutherland JM, Fisher ES. Survival after hepatic resection of colorectal cancer metastases: a national experience. Cancer. 2009 Feb 15; 115(4):752-9.
    View in: PubMed
  29. Weeks WB, Wallace AE, Wallace TA, Gottlieb DJ. Does the VA offer good health care value? J Health Care Finance. 2009; 35(4):1-12.
    View in: PubMed
  30. Gottlieb DJ. The Sleep Heart Health Study: a progress report. Curr Opin Pulm Med. 2008 Nov; 14(6):537-42.
    View in: PubMed
  31. Kapur VK, Resnick HE, Gottlieb DJ. Sleep disordered breathing and hypertension: does self-reported sleepiness modify the association? Sleep. 2008 Aug; 31(8):1127-32.
    View in: PubMed
  32. Stamatakis K, Sanders MH, Caffo B, Resnick HE, Gottlieb DJ, Mehra R, Punjabi NM. Fasting glycemia in sleep disordered breathing: lowering the threshold on oxyhemoglobin desaturation. Sleep. 2008 Jul; 31(7):1018-24.
    View in: PubMed
  33. Wang W, Tretriluxana S, Redline S, Surovec S, Gottlieb DJ, Khoo MC. Association of cardiac autonomic function measures with severity of sleep-disordered breathing in a community-based sample. J Sleep Res. 2008 Sep; 17(3):251-62.
    View in: PubMed
  34. Aros B, Tosteson AN, Gottlieb DJ, Koval KJ. Is a sliding hip screw or im nail the preferred implant for intertrochanteric fracture fixation? Clin Orthop Relat Res. 2008 Nov; 466(11):2827-32.
    View in: PubMed
  35. Chami HA, Devereux RB, Gottdiener JS, Mehra R, Roman MJ, Benjamin EJ, Gottlieb DJ. Left ventricular morphology and systolic function in sleep-disordered breathing: the Sleep Heart Health Study. Circulation. 2008 May 20; 117(20):2599-607.
    View in: PubMed
  36. Gottlieb D, Schwartz ML, Bischoff K, Gauvreau K, Mayer JE. Predictors of outcome of arterial switch operation for complex D-transposition. Ann Thorac Surg. 2008 May; 85(5):1698-702; discussion 1702-3.
    View in: PubMed
  37. Radley DC, Gottlieb DJ, Fisher ES, Tosteson AN. Comorbidity risk-adjustment strategies are comparable among persons with hip fracture. J Clin Epidemiol. 2008 Jun; 61(6):580-7.
    View in: PubMed
  38. Seicean S, Kirchner HL, Gottlieb DJ, Punjabi NM, Resnick H, Sanders M, Budhiraja R, Singer M, Redline S. Sleep-disordered breathing and impaired glucose metabolism in normal-weight and overweight/obese individuals: the Sleep Heart Health Study. Diabetes Care. 2008 May; 31(5):1001-6.
    View in: PubMed
  39. Winkelman JW, Shahar E, Sharief I, Gottlieb DJ. Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study. Neurology. 2008 Jan 1; 70(1):35-42.
    View in: PubMed
  40. Collop NA, Anderson WM, Boehlecke B, Claman D, Goldberg R, Gottlieb DJ, Hudgel D, Sateia M, Schwab R. Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. Portable Monitoring Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 2007 Dec 15; 3(7):737-47.
    View in: PubMed
  41. Thomas RJ, Mietus JE, Peng CK, Gilmartin G, Daly RW, Goldberger AL, Gottlieb DJ. Differentiating obstructive from central and complex sleep apnea using an automated electrocardiogram-based method. Sleep. 2007 Dec; 30(12):1756-69.
    View in: PubMed
  42. Gottlieb DJ, O'Connor GT, Wilk JB. Genome-wide association of sleep and circadian phenotypes. BMC Med Genet. 2007; 8 Suppl 1:S9.
    View in: PubMed
  43. Wilk JB, Walter RE, Laramie JM, Gottlieb DJ, O'Connor GT. Framingham Heart Study genome-wide association: results for pulmonary function measures. BMC Med Genet. 2007; 8 Suppl 1:S8.
    View in: PubMed
  44. Welch HG, Fisher ES, Gottlieb DJ, Barry MJ. Detection of prostate cancer via biopsy in the Medicare-SEER population during the PSA era. J Natl Cancer Inst. 2007 Sep 19; 99(18):1395-400.
    View in: PubMed
  45. Stukel TA, Fisher ES, Wennberg DE, Alter DA, Gottlieb DJ, Vermeulen MJ. Analysis of observational studies in the presence of treatment selection bias: effects of invasive cardiac management on AMI survival using propensity score and instrumental variable methods. JAMA. 2007 Jan 17; 297(3):278-85.
    View in: PubMed
  46. Wilk JB, Herbert A, Shoemaker CM, Gottlieb DJ, Karamohamed S. Secreted modular calcium-binding protein 2 haplotypes are associated with pulmonary function. Am J Respir Crit Care Med. 2007 Mar 15; 175(6):554-60.
    View in: PubMed
  47. Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet. 2007; 8 Suppl 1:S1.
    View in: PubMed
  48. Fisher ES, Staiger DO, Bynum JP, Gottlieb DJ. Creating accountable care organizations: the extended hospital medical staff. Health Aff (Millwood). 2007 Jan-Feb; 26(1):w44-57.
    View in: PubMed
  49. Patwardhan AA, Larson MG, Levy D, Benjamin EJ, Leip EP, Keyes MJ, Wang TJ, Gottlieb DJ, Vasan RS. Obstructive sleep apnea and plasma natriuretic peptide levels in a community-based sample. Sleep. 2006 Oct; 29(10):1301-6.
    View in: PubMed
  50. Patel SR, Malhotra A, White DP, Gottlieb DJ, Hu FB. Association between reduced sleep and weight gain in women. Am J Epidemiol. 2006 Nov 15; 164(10):947-54.
    View in: PubMed
  51. Gottlieb DJ, Redline S, Nieto FJ, Baldwin CM, Newman AB, Resnick HE, Punjabi NM. Association of usual sleep duration with hypertension: the Sleep Heart Health Study. Sleep. 2006 Aug; 29(8):1009-14.
    View in: PubMed
  52. Kushida CA, Nichols DA, Quan SF, Goodwin JL, White DP, Gottlieb DJ, Walsh JK, Schweitzer PK, Guilleminault C, Simon RD, Leary EB, Hyde PR, Holmes TH, Bloch DA, Green S, McEvoy LK, Gevins A, Dement WC. The Apnea Positive Pressure Long-term Efficacy Study (APPLES): rationale, design, methods, and procedures. J Clin Sleep Med. 2006 Jul 15; 2(3):288-300.
    View in: PubMed
  53. Patel SR, Malhotra A, Gottlieb DJ, White DP, Hu FB. Correlates of long sleep duration. Sleep. 2006 Jul; 29(7):881-9.
    View in: PubMed
  54. Sirovich BE, Gottlieb DJ, Welch HG, Fisher ES. Regional variations in health care intensity and physician perceptions of quality of care. Ann Intern Med. 2006 May 2; 144(9):641-9.
    View in: PubMed
  55. Mehra R, Benjamin EJ, Shahar E, Gottlieb DJ, Nawabit R, Kirchner HL, Sahadevan J, Redline S. Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study. Am J Respir Crit Care Med. 2006 Apr 15; 173(8):910-6.
    View in: PubMed
  56. Gottlieb DJ. Can sleep apnea be treated without modifying anatomy? N Engl J Med. 2005 Dec 15; 353(24):2604-6.
    View in: PubMed
  57. Sirovich BE, Gottlieb DJ, Welch HG, Fisher ES. Variation in the tendency of primary care physicians to intervene. Arch Intern Med. 2005 Oct 24; 165(19):2252-6.
    View in: PubMed
  58. Gottlieb DJ. The future risks of childhood sleep-disordered breathing. Sleep. 2005 Jul; 28(7):796-7.
    View in: PubMed
  59. Gottlieb DJ, Punjabi NM, Newman AB, Resnick HE, Redline S, Baldwin CM, Nieto FJ. Association of sleep time with diabetes mellitus and impaired glucose tolerance. Arch Intern Med. 2005 Apr 25; 165(8):863-7.
    View in: PubMed
  60. Kapur VK, Baldwin CM, Resnick HE, Gottlieb DJ, Nieto FJ. Sleepiness in patients with moderate to severe sleep-disordered breathing. Sleep. 2005 Apr; 28(4):472-7.
    View in: PubMed
  61. Gottlieb DJ, Chase C, Vezina RM, Heeren TC, Corwin MJ, Auerbach SH, Weese-Mayer DE, Lesko SM. Sleep-disordered breathing symptoms are associated with poorer cognitive function in 5-year-old children. J Pediatr. 2004 Oct; 145(4):458-64.
    View in: PubMed
  62. Punjabi NM, Shahar E, Redline S, Gottlieb DJ, Givelber R, Resnick HE. Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study. Am J Epidemiol. 2004 Sep 15; 160(6):521-30.
    View in: PubMed
  63. DeMolles DA, Sparrow D, Gottlieb DJ, Friedman R. A pilot trial of a telecommunications system in sleep apnea management. Med Care. 2004 Aug; 42(8):764-9.
    View in: PubMed
  64. Iber C, Redline S, Kaplan Gilpin AM, Quan SF, Zhang L, Gottlieb DJ, Rapoport D, Resnick HE, Sanders M, Smith P. Polysomnography performed in the unattended home versus the attended laboratory setting--Sleep Heart Health Study methodology. Sleep. 2004 May 1; 27(3):536-40.
    View in: PubMed
  65. Redline S, Kirchner HL, Quan SF, Gottlieb DJ, Kapur V, Newman A. The effects of age, sex, ethnicity, and sleep-disordered breathing on sleep architecture. Arch Intern Med. 2004 Feb 23; 164(4):406-18.
    View in: PubMed
  66. Fisher ES, Wennberg DE, Stukel TA, Gottlieb DJ. Variations in the longitudinal efficiency of academic medical centers. Health Aff (Millwood). 2004; Suppl Variation:VAR19-32.
    View in: PubMed
  67. Gottlieb DJ, Vezina RM, Chase C, Lesko SM, Heeren TC, Weese-Mayer DE, Auerbach SH, Corwin MJ. Symptoms of sleep-disordered breathing in 5-year-old children are associated with sleepiness and problem behaviors. Pediatrics. 2003 Oct; 112(4):870-7.
    View in: PubMed
  68. Wilk JB, DeStefano AL, Joost O, Myers RH, Cupples LA, Slater K, Atwood LD, Heard-Costa NL, Herbert A, O'Connor GT, Gottlieb DJ. Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study. Hum Mol Genet. 2003 Nov 1; 12(21):2745-51.
    View in: PubMed
  69. McTaggart RA, Gottlieb D, Brooks J, Bacchetti P, Roberts JP, Tomlanovich S, Feng S. Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation. Am J Transplant. 2003 Apr; 3(4):416-23.
    View in: PubMed
  70. Walter RE, Beiser A, Givelber RJ, O'Connor GT, Gottlieb DJ. Association between glycemic state and lung function: the Framingham Heart Study. Am J Respir Crit Care Med. 2003 Mar 15; 167(6):911-6.
    View in: PubMed
  71. Wilk JB, DeStefano AL, Arnett DK, Rich SS, Djousse L, Crapo RO, Leppert MF, Province MA, Cupples LA, Gottlieb DJ, Myers RH. A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Respir Crit Care Med. 2003 Jun 1; 167(11):1528-33.
    View in: PubMed
  72. Fisher ES, Wennberg DE, Stukel TA, Gottlieb DJ, Lucas FL, Pinder EL. The implications of regional variations in Medicare spending. Part 1: the content, quality, and accessibility of care. Ann Intern Med. 2003 Feb 18; 138(4):273-87.
    View in: PubMed
  73. Fisher ES, Wennberg DE, Stukel TA, Gottlieb DJ, Lucas FL, Pinder EL. The implications of regional variations in Medicare spending. Part 2: health outcomes and satisfaction with care. Ann Intern Med. 2003 Feb 18; 138(4):288-98.
    View in: PubMed
  74. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med. 2002 May 1; 165(9):1217-39.
    View in: PubMed
  75. Young T, Shahar E, Nieto FJ, Redline S, Newman AB, Gottlieb DJ, Walsleben JA, Finn L, Enright P, Samet JM. Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study. Arch Intern Med. 2002 Apr 22; 162(8):893-900.
    View in: PubMed
  76. Joost O, Wilk JB, Cupples LA, Harmon M, Shearman AM, Baldwin CT, O'Connor GT, Myers RH, Gottlieb DJ. Genetic loci influencing lung function: a genome-wide scan in the Framingham Study. Am J Respir Crit Care Med. 2002 Mar 15; 165(6):795-9.
    View in: PubMed
  77. Gottlieb DJ. Cardiac pacing--a novel therapy for sleep apnea? N Engl J Med. 2002 Feb 7; 346(6):444-5.
    View in: PubMed
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