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Last Name

Chuan Wu, Ph.D.

TitleInstructor in Neurology
InstitutionBrigham and Women's Hospital
AddressHarvard Medical School
333 Longwood Ave
Boston MA 02115

 awards and honors
2014 - National Multiple Sclerosis Society Career Transition Award, USA
2013 - Regeneron Prize for Outstanding Research, USA
2013 - 2013 Harvard Chinese Life Sciences Research Award, Harvard Medical School
2013 - The American Association of Immunologists (AAI) Trainee Abstract Award, USA
2013 - National Multiple Sclerosis Society Postdoctoral Fellowship Award, USA
2009 - Eckhart-Buddecke prize for Pro Scientia-Preises der Eckhart-Buddecke-Stiftung, Münster University
2009 - PhD student with outstanding performance (summa cum laude), Münster University, Germany
2004 - 2005Medical Faculty Stipend, Lund University, Sweden

 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Zhang X, Wu C, Song J, Götte M, Sorokin L. Syndecan-1, a Cell Surface Proteoglycan, Negatively Regulates Initial Leukocyte Recruitment to the Brain across the Choroid Plexus in Murine Experimental Autoimmune Encephalomyelitis. J Immunol. 2013 Nov 1; 191(9):4551-61.
    View in: PubMed
  2. Zhu B, Buttrick T, Bassil R, Zhu C, Olah M, Wu C, Xiao S, Orent W, Elyaman W, Khoury SJ. IL-4 and Retinoic Acid Synergistically Induce Regulatory Dendritic Cells Expressing Aldh1a2. J Immunol. 2013 Sep 15; 191(6):3139-51.
    View in: PubMed
  3. Song J, Lokmic Z, Lämmermann T, Rolf J, Wu C, Zhang X, Hallmann R, Hannocks MJ, Horn N, Ruegg MA, Sonnenberg A, Georges-Labouesse E, Winkler TH, Kearney JF, Cardell S, Sorokin L. Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):E2915-24.
    View in: PubMed
  4. Wu C, Pot C, Apetoh L, Thalhamer T, Zhu B, Murugaiyan G, Xiao S, Lee Y, Rangachari M, Yosef N, Kuchroo VK. Metallothioneins negatively regulate IL-27-induced type 1 regulatory T-cell differentiation. Proc Natl Acad Sci U S A. 2013 May 7; 110(19):7802-7.
    View in: PubMed
  5. Wu C, Yosef N, Thalhamer T, Zhu C, Xiao S, Kishi Y, Regev A, Kuchroo VK. Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Nature. 2013 Apr 25; 496(7446):513-7.
    View in: PubMed
  6. Yosef N, Shalek AK, Gaublomme JT, Jin H, Lee Y, Awasthi A, Wu C, Karwacz K, Xiao S, Jorgolli M, Gennert D, Satija R, Shakya A, Lu DY, Trombetta JJ, Pillai MR, Ratcliffe PJ, Coleman ML, Bix M, Tantin D, Park H, Kuchroo VK, Regev A. Dynamic regulatory network controlling TH17 cell differentiation. Nature. 2013 Apr 25; 496(7446):461-8.
    View in: PubMed
  7. Song J, Wu C, Zhang X, Sorokin LM. In Vivo Processing of CXCL5 (LIX) by Matrix Metalloproteinase (MMP)-2 and MMP-9 Promotes Early Neutrophil Recruitment in IL-1ß-Induced Peritonitis. J Immunol. 2013 Jan 1; 190(1):401-10.
    View in: PubMed
  8. Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Induction and molecular signature of pathogenic TH17 cells. Nat Immunol. 2012 Oct; 13(10):991-9.
    View in: PubMed
  9. Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):12105-10.
    View in: PubMed
  10. Zhu B, Kennedy JK, Wang Y, Sandoval-Garcia C, Cao L, Xiao S, Wu C, Elyaman W, Khoury SJ. Plasticity of Ly-6C(hi) myeloid cells in T cell regulation. J Immunol. 2011 Sep 1; 187(5):2418-32.
    View in: PubMed
  11. Korpos E, Wu C, Song J, Hallmann R, Sorokin L. Role of the extracellular matrix in lymphocyte migration. Cell Tissue Res. 2010 Jan; 339(1):47-57.
    View in: PubMed
  12. Wu C, Rauch U, Korpos E, Song J, Loser K, Crocker PR, Sorokin LM. Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression. J Immunol. 2009 May 15; 182(10):6508-16.
    View in: PubMed
  13. Wu C, Ivars F, Anderson P, Hallmann R, Vestweber D, Nilsson P, Robenek H, Tryggvason K, Song J, Korpos E, Loser K, Beissert S, Georges-Labouesse E, Sorokin LM. Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain. Nat Med. 2009 May; 15(5):519-27.
    View in: PubMed
  14. Korpos E, Wu C, Sorokin L. Multiple roles of the extracellular matrix in inflammation. Curr Pharm Des. 2009; 15(12):1349-57.
    View in: PubMed
  15. Zhang YX, Li J, Guo XK, Wu C, Bi B, Ren SX, Wu CF, Zhao GP. Characterization of a novel toxin-antitoxin module, VapBC, encoded by Leptospira interrogans chromosome. Cell Res. 2004 Jun; 14(3):208-16.
    View in: PubMed
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