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Anne Louise Oaklander, PH.D., M.D.

TitleAssociate Professor of Neurology
InstitutionMassachusetts General Hospital
DepartmentNeurology
AddressMassachusetts General Hospital
Warren 310 - 275 Charles St
55 Fruit St
Boston MA 02114
Phone617/724-3992
Fax617/726-6991

 Mentoring 
 completed student projects
A Prospective Skin Biopsy Study of Shingles Pain and post-Herpetic Neuralgia (PHN) PASTEUR
Summer, 06/26/00 - 08/18/00

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Oaklander AL, Klein MM. Evidence of small-fiber polyneuropathy in unexplained, juvenile-onset, widespread pain syndromes. Pediatrics. 2013 Apr; 131(4):e1091-100.
    View in: PubMed
  2. Oaklander AL, Long DM, Larvie M, Davidson CJ. Case records of the Massachusetts General Hospital. Case 7-2013. A 77-year-old woman with long-standing unilateral thoracic pain and incontinence. N Engl J Med. 2013 Feb 28; 368(9):853-61.
    View in: PubMed
  3. Harden RN, Oaklander AL, Burton AW, Perez RS, Richardson K, Swan M, Barthel J, Costa B, Graciosa JR, Bruehl S. Complex regional pain syndrome: practical diagnostic and treatment guidelines, 4th edition. Pain Med. 2013 Feb; 14(2):180-229.
    View in: PubMed
  4. Cohen-Adad J, Zhao W, Wald LL, Oaklander AL. 7T MRI of spinal cord injury. Neurology. 2012 Nov 27; 79(22):2217.
    View in: PubMed
  5. Oaklander AL. Development of CRPS after shingles: It's all about location. Pain. 2012 Dec; 153(12):2309-10.
    View in: PubMed
  6. Cohen-Adad J, Buchbinder B, Oaklander AL. Cervical spinal cord injection of epidural corticosteroids: Comprehensive longitudinal study including multiparametric magnetic resonance imaging. Pain. 2012 Nov; 153(11):2292-9.
    View in: PubMed
  7. Oaklander AL. Tarlov cysts. Neurosurg Focus. 2012 Apr; 32(4):E9; author reply E9.
    View in: PubMed
  8. Curtis AR, Oaklander AL, Johnson A, Yosipovitch G. Trigeminal trophic syndrome from stroke: an under-recognized central neuropathic itch syndrome. Am J Clin Dermatol. 2012 Apr 1; 13(2):125-8.
    View in: PubMed
  9. Oaklander AL. Common neuropathic itch syndromes. Acta Derm Venereol. 2012 Mar; 92(2):118-25.
    View in: PubMed
  10. Oaklander AL. Bilateral somatosensory cortex disinhibition in complex regional pain syndrome type I. Neurology. 2012 Feb 21; 78(8):606; author reply 606-7.
    View in: PubMed
  11. Oaklander AL, Wilson PR, Moskovitz PA, Manning DC, Lubenow T, Levine JD, Harden RN, Galer BS, Cooper MS, Bruehl S, Broatch J, Berde C, Bennett GJ. Response to "A new definition of neuropathic pain". Pain. 2012 Apr; 153(4):934-5; author reply 935-6.
    View in: PubMed
  12. Klein MM, Lee JW, Siegel SM, Downs HM, Oaklander AL. Endoneurial pathology of the needlestick-nerve-injury model of Complex Regional Pain Syndrome, including rats with and without pain behaviors. Eur J Pain. 2012 Jan; 16(1):28-37.
    View in: PubMed
  13. Oaklander AL. Neuropathic itch. Semin Cutan Med Surg. 2011 Jun; 30(2):87-92.
    View in: PubMed
  14. Boykin RE, Friedman DJ, Zimmer ZR, Oaklander AL, Higgins LD, Warner JJ. Suprascapular neuropathy in a shoulder referral practice. J Shoulder Elbow Surg. 2011 Sep; 20(6):983-8.
    View in: PubMed
  15. Unal-Cevik I, Oaklander AL. Comparing partial and total tibial-nerve axotomy: long-term effects on prevalence and location of evoked pain behaviors. Pain Pract. 2011 Mar-Apr; 11(2):109-19.
    View in: PubMed
  16. Hiers RH, Long D, North RB, Oaklander AL. Hiding in plain sight: a case of Tarlov perineural cysts. J Pain. 2010 Sep; 11(9):833-7.
    View in: PubMed
  17. Oaklander AL. Role of minimal distal nerve injury in complex regional pain syndrome-I. Pain Med. 2010 Aug; 11(8):1251-6.
    View in: PubMed
  18. Oaklander AL, Fields HL. Reply: Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy? Ann Neurol. 2010 Jul; 68(1):116-7.
    View in: PubMed
  19. Opstelten W, McElhaney J, Weinberger B, Oaklander AL, Johnson RW. The impact of varicella zoster virus: chronic pain. J Clin Virol. 2010 May; 48 Suppl 1:S8-13.
    View in: PubMed
  20. Whitley RJ, Volpi A, McKendrick M, Wijck Av, Oaklander AL. Management of herpes zoster and post-herpetic neuralgia now and in the future. J Clin Virol. 2010 May; 48 Suppl 1:S20-8.
    View in: PubMed
  21. Gershon AA, Gershon MD, Breuer J, Levin MJ, Oaklander AL, Griffiths PD. Advances in the understanding of the pathogenesis and epidemiology of herpes zoster. J Clin Virol. 2010 May; 48 Suppl 1:S2-7.
    View in: PubMed
  22. Oaklander AL. Neuropathic pruritus following Wallenberg syndrome. Neurology. 2009 Nov 10; 73(19):1605; author reply 1605-6.
    View in: PubMed
  23. Wood GJ, Akiyama T, Carstens E, Oaklander AL, Yosipovitch G. An insatiable itch. J Pain. 2009 Aug; 10(8):792-7.
    View in: PubMed
  24. Richardson PG, Xie W, Mitsiades C, Chanan-Khan AA, Lonial S, Hassoun H, Avigan DE, Oaklander AL, Kuter DJ, Wen PY, Kesari S, Briemberg HR, Schlossman RL, Munshi NC, Heffner LT, Doss D, Esseltine DL, Weller E, Anderson KC, Amato AA. Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy. J Clin Oncol. 2009 Jul 20; 27(21):3518-25.
    View in: PubMed
  25. Oaklander AL, Fields HL. Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy? Ann Neurol. 2009 Jun; 65(6):629-38.
    View in: PubMed
  26. Wei T, Li WW, Guo TZ, Zhao R, Wang L, Clark DJ, Oaklander AL, Schmelz M, Kingery WS. Post-junctional facilitation of Substance P signaling in a tibia fracture rat model of complex regional pain syndrome type I. Pain. 2009 Aug; 144(3):278-86.
    View in: PubMed
  27. Dussor G, Koerber HR, Oaklander AL, Rice FL, Molliver DC. Nucleotide signaling and cutaneous mechanisms of pain transduction. Brain Res Rev. 2009 Apr; 60(1):24-35.
    View in: PubMed
  28. Lee JW, Siegel SM, Oaklander AL. Effects of distal nerve injuries on dorsal-horn neurons and glia: relationships between lesion size and mechanical hyperalgesia. Neuroscience. 2009 Jan 23; 158(2):904-14.
    View in: PubMed
  29. Oaklander AL. RSD/CRPS: the end of the beginning. Pain. 2008 Oct 15; 139(2):239-40.
    View in: PubMed
  30. Brewer KL, Lee JW, Downs H, Oaklander AL, Yezierski RP. Dermatomal scratching after intramedullary quisqualate injection: correlation with cutaneous denervation. J Pain. 2008 Nov; 9(11):999-1005.
    View in: PubMed
  31. Dworkin RH, Gnann JW, Oaklander AL, Raja SN, Schmader KE, Whitley RJ. Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia. J Pain. 2008 Jan; 9(1 Suppl 1):S37-44.
    View in: PubMed
  32. Oaklander AL. Mechanisms of pain and itch caused by herpes zoster (shingles). J Pain. 2008 Jan; 9(1 Suppl 1):S10-8.
    View in: PubMed
  33. Siegel SM, Lee JW, Oaklander AL. Needlestick distal nerve injury in rats models symptoms of complex regional pain syndrome. Anesth Analg. 2007 Dec; 105(6):1820-9, table of contents.
    View in: PubMed
  34. Ishizuka K, Oaklander AL, Chiocca EA. A retrospective analysis of reasons for reoperation following initially successful peripheral nerve stimulation. J Neurosurg. 2007 Mar; 106(3):388-90.
    View in: PubMed
  35. Paticoff J, Valovska A, Nedeljkovic SS, Oaklander AL. Defining a treatable cause of erythromelalgia: acute adolescent autoimmune small-fiber axonopathy. Anesth Analg. 2007 Feb; 104(2):438-41.
    View in: PubMed
  36. Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, Betts RF, Gershon AA, Haanpaa ML, McKendrick MW, Nurmikko TJ, Oaklander AL, Oxman MN, Pavan-Langston D, Petersen KL, Rowbotham MC, Schmader KE, Stacey BR, Tyring SK, van Wijck AJ, Wallace MS, Wassilew SW, Whitley RJ. Recommendations for the management of herpes zoster. Clin Infect Dis. 2007 Jan 1; 44 Suppl 1:S1-26.
    View in: PubMed
  37. Oaklander AL. Response to "Pain" editorial re: Oaklander et al. (2006). Pain. 2006 Jul; 123(1-2):217-8.
    View in: PubMed
  38. Stoler JM, Oaklander AL. Patients with Ehlers Danlos syndrome and CRPS: a possible association? Pain. 2006 Jul; 123(1-2):204-9.
    View in: PubMed
  39. Oaklander AL, Buchbinder BR. Reply to Prilipko et al. Ann Neurol. 2006 Apr; 59(4):724-5.
    View in: PubMed
  40. Fink E, Oaklander AL. Small-fiber neuropathy: answering the burning questions. Sci Aging Knowledge Environ. 2006 Mar 8; 2006(6):pe7.
    View in: PubMed
  41. Oaklander AL, Rissmiller JG, Gelman LB, Zheng L, Chang Y, Gott R. Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy). Pain. 2006 Feb; 120(3):235-43.
    View in: PubMed
  42. Oaklander AL. Chapter 31 Neuropathological examination of peripheral nerves in painful neuropathies (neuralgias). Handb Clin Neurol. 2006; 81:463-XII.
    View in: PubMed
  43. Watson CP, Oaklander AL. Chapter 44 Postherpetic neuralgia. Handb Clin Neurol. 2006; 81:661-77.
    View in: PubMed
  44. Oaklander AL, Siegel SM. Cutaneous innervation: form and function. J Am Acad Dermatol. 2005 Dec; 53(6):1027-37.
    View in: PubMed
  45. Jung BF, Herrmann D, Griggs J, Oaklander AL, Dworkin RH. Neuropathic pain associated with non-surgical treatment of breast cancer. Pain. 2005 Nov; 118(1-2):10-4.
    View in: PubMed
  46. Oaklander AL, Buchbinder BR. Pregabalin-withdrawal encephalopathy and splenial edema: a link to high-altitude illness? Ann Neurol. 2005 Aug; 58(2):309-12.
    View in: PubMed
  47. Oaklander A. Erythromelalgia: small-fiber neuropathy by any other name? Pediatrics. 2005 Jul; 116(1):293-4; author reply 294-5.
    View in: PubMed
  48. Dey DD, Landrum O, Oaklander AL. Central neuropathic itch from spinal-cord cavernous hemangioma: a human case, a possible animal model, and hypotheses about pathogenesis. Pain. 2005 Jan; 113(1-2):233-7.
    View in: PubMed
  49. Oaklander AL. Progression of dystonia in complex regional pain syndrome. Neurology. 2004 Aug 24; 63(4):751.
    View in: PubMed
  50. Amato AA, Oaklander AL. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2004. A 76-year-old woman with numbness and pain in the feet and legs. N Engl J Med. 2004 May 20; 350(21):2181-9.
    View in: PubMed
  51. Oaklander AL, Brown JM. Unilateral nerve injury produces bilateral loss of distal innervation. Ann Neurol. 2004 May; 55(5):639-44.
    View in: PubMed
  52. Oaklander AL, Bowsher D, Galer B, Haanpää M, Jensen MP. Herpes zoster itch: preliminary epidemiologic data. J Pain. 2003 Aug; 4(6):338-43.
    View in: PubMed
  53. Jung BF, Ahrendt GM, Oaklander AL, Dworkin RH. Neuropathic pain following breast cancer surgery: proposed classification and research update. Pain. 2003 Jul; 104(1-2):1-13.
    View in: PubMed
  54. Hord ED, Oaklander AL. Complex regional pain syndrome: a review of evidence-supported treatment options. Curr Pain Headache Rep. 2003 Jun; 7(3):188-96.
    View in: PubMed
  55. Nagasako EM, Oaklander AL, Dworkin RH. Congenital insensitivity to pain: an update. Pain. 2003 Feb; 101(3):213-9.
    View in: PubMed
  56. Oaklander AL, Stocks EA, Mouton PR. Number of Langerhans immune cells in painful and non-painful human skin after shingles. Arch Dermatol Res. 2003 Mar; 294(12):529-35.
    View in: PubMed
  57. Watson CP, Oaklander AL. Postherpetic neuralgia. Pain Pract. 2002 Dec; 2(4):295-307.
    View in: PubMed
  58. Oaklander AL, Rissmiller JG. Postherpetic neuralgia after shingles: an under-recognized cause of chronic vulvar pain. Obstet Gynecol. 2002 Apr; 99(4):625-8.
    View in: PubMed
  59. Oaklander AL, Cohen SP, Raju SV. Intractable postherpetic itch and cutaneous deafferentation after facial shingles. Pain. 2002 Mar; 96(1-2):9-12.
    View in: PubMed
  60. Oaklander AL. The density of remaining nerve endings in human skin with and without postherpetic neuralgia after shingles. Pain. 2001 May; 92(1-2):139-45.
    View in: PubMed
  61. Pappagallo M, Oaklander AL, Quatrano-Piacentini AL, Clark MR, Raja SN. Heterogenous patterns of sensory dysfunction in postherpetic neuralgia suggest multiple pathophysiologic mechanisms. Anesthesiology. 2000 Mar; 92(3):691-8.
    View in: PubMed
  62. Oaklander AL. The pathology of shingles: Head and Campbell's 1900 monograph. Arch Neurol. 1999 Oct; 56(10):1292-4.
    View in: PubMed
  63. Oaklander AL, Romans K, Horasek S, Stocks A, Hauer P, Meyer RA. Unilateral postherpetic neuralgia is associated with bilateral sensory neuron damage. Ann Neurol. 1998 Nov; 44(5):789-95.
    View in: PubMed
  64. Oaklander AL, Belzberg AJ. Unilateral nerve injury down-regulates mRNA for Na+ channel SCN10A bilaterally in rat dorsal root ganglia. Brain Res Mol Brain Res. 1997 Dec 1; 52(1):162-5.
    View in: PubMed
  65. Oaklander AL, Ekenberg SJ. Small-scale magnetic isolation of mRNA and synthesis of cDNA in 96-well plates. Nature. 1994 Oct 13; 371(6498):631-2.
    View in: PubMed
  66. Oaklander AL, Spencer PS. Cold blockade of axonal transport activates premitotic activity of Schwann cells and wallerian degeneration. J Neurochem. 1988 Feb; 50(2):490-6.
    View in: PubMed
  67. Oaklander AL, Miller MS, Spencer PS. Early changes in degenerating mouse sciatic nerve are associated with endothelial cells. Brain Res. 1987 Sep 1; 419(1-2):39-45.
    View in: PubMed
  68. Oaklander AL, Miller MS, Spencer PS. Rapid anterograde spread of premitotic activity along degenerating cat sciatic nerve. J Neurochem. 1987 Jan; 48(1):111-4.
    View in: PubMed
  69. Oaklander AL, Pellegrino RG, Ritchie JM. Saxitoxin binding to central and peripheral nervous tissue of the myelin deficiency (md) mutant rat. Brain Res. 1984 Jul 30; 307(1-2):393-7.
    View in: PubMed
  70. Politis MJ, Pellegrino RG, Oaklander AL, Ritchie JM. Reactive glial protein synthesis and early disappearance of saxitoxin binding in degenerating rat optic nerve. Brain Res. 1983 Aug 29; 273(2):392-5.
    View in: PubMed
  71. Scheinberg L, Holland NJ, Kirschenbaum M, Oaklander A, Geronemus DF. Comprehensive long-term care of patients with multiple sclerosis. Neurology. 1981 Sep; 31(9):1121-3.
    View in: PubMed
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