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Yi Hsiang Hsu, Sc.D.

TitleAssistant Professor of Medicine
InstitutionHebrew Rehabilitation Center
DepartmentMedicine
AddressHebrew Rehab Center For the Aged
Institute for Aging Research
1200 Centre St
Roslindale MA 02131
Phone617/363-8393
Other Positions
TitleVisiting Scientist
InstitutionHarvard School of Public Health
DepartmentEH - Molecular+Integrative Phys Sci Prog


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wang LJ, Chen PR, Hsu LP, Hsu WL, Liu DW, Chang CH, Hsu YC, Lee JW. Concomitant induction of apoptosis and autophagy by prostate apoptosis response-4 in hypopharyngeal carcinoma cells. Am J Pathol. 2014 Feb; 184(2):418-30.
    View in: PubMed
  2. Hannan MT, Menz HB, Jordan JM, Cupples LA, Cheng CH, Hsu YH. High heritability of hallux valgus and lesser toe deformities in adult men and women. Arthritis Care Res (Hoboken). 2013 Sep; 65(9):1515-21.
    View in: PubMed
  3. Hsu YH, Kiel DP. Clinical review: Genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1958-77.
    View in: PubMed
  4. Billings LK, Hsu YH, Ackerman RJ, Dupuis J, Voight BF, Rasmussen-Torvik LJ, Hercberg S, Lathrop M, Barnes D, Langenberg C, Hui J, Fu M, Bouatia-Naji N, Lecoeur C, An P, Magnusson PK, Surakka I, Ripatti S, Christiansen L, Dalgård C, Folkersen L, Grundberg E, Eriksson P, Kaprio J, Ohm Kyvik K, Pedersen NL, Borecki IB, Province MA, Balkau B, Froguel P, Shuldiner AR, Palmer LJ, Wareham N, Meneton P, Johnson T, Pankow JS, Karasik D, Meigs JB, Kiel DP, Florez JC. Impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes. 2012 Aug; 61(8):2176-86.
    View in: PubMed
  5. Chen CH, Lee O, Yao CN, Chuang MY, Chang YL, Chang MH, Wen YF, Yang WH, Ko CH, Chou NT, Lin MW, Lai CP, Sun CY, Wang LM, Chen YC, Hseu TH, Chang CN, Hsu HC, Lin HC, Chang YL, Shih YC, Chou SH, Hsu YL, Tseng HW, Liu CP, Tu CM, Hu TL, Tsai YJ, Chen TS, Lin CL, Chiou SJ, Liu CC, Hwang CS. Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2010 Oct 15; 20(20):6129-32.
    View in: PubMed
  6. Karasik D, Hsu YH, Zhou Y, Cupples LA, Kiel DP, Demissie S. Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. J Bone Miner Res. 2010 Jul; 25(7):1555-63.
    View in: PubMed
  7. Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, Soranzo N, Bianchi EN, Grundberg E, Liang L, Richards JB, Estrada K, Zhou Y, van Nas A, Moffatt MF, Zhai G, Hofman A, van Meurs JB, Pols HA, Price RI, Nilsson O, Pastinen T, Cupples LA, Lusis AJ, Schadt EE, Ferrari S, Uitterlinden AG, Rivadeneira F, Spector TD, Karasik D, Kiel DP. An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet. 2010 Jun; 6(6):e1000977.
    View in: PubMed
  8. Chen MH, Larson MG, Hsu YH, Peloso GM, Guo CY, Fox CS, Atwood LD, Yang Q. A three-stage approach for genome-wide association studies with family data for quantitative traits. BMC Genet. 2010; 11:40.
    View in: PubMed
  9. Hajjar I, Sorond F, Hsu YH, Galica A, Cupples LA, Lipsitz LA. Renin angiotensin system gene polymorphisms and cerebral blood flow regulation: the MOBILIZE Boston study. Stroke. 2010 Apr; 41(4):635-40.
    View in: PubMed
  10. Kung AW, Xiao SM, Cherny S, Li GH, Gao Y, Tso G, Lau KS, Luk KD, Liu JM, Cui B, Zhang MJ, Zhang ZL, He JW, Yue H, Xia WB, Luo LM, He SL, Kiel DP, Karasik D, Hsu YH, Cupples LA, Demissie S, Styrkarsdottir U, Halldorsson BV, Sigurdsson G, Thorsteinsdottir U, Stefansson K, Richards JB, Zhai G, Soranzo N, Valdes A, Spector TD, Sham PC. Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet. 2010 Feb 12; 86(2):229-39.
    View in: PubMed
  11. Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu YH, Zillikens MC, Wilson SG, Mullin BH, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra BA, Pols HA, Sigurdsson G, Thorsteinsdottir U, Soranzo N, Williams FM, Zhou Y, Ralston SH, Thorleifsson G, van Duijn CM, Kiel DP, Stefansson K, Uitterlinden AG, Ioannidis JP, Spector TD. Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med. 2009 Oct 20; 151(8):528-37.
    View in: PubMed
  12. Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra B, Pastinen T, Pols HA, Sigurdsson G, Soranzo N, Thorleifsson G, Thorsteinsdottir U, Williams FM, Wilson SG, Zhou Y, Ralston SH, van Duijn CM, Spector T, Kiel DP, Stefansson K, Ioannidis JP, Uitterlinden AG. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet. 2009 Nov; 41(11):1199-206.
    View in: PubMed
  13. Chua CS, Lin YM, Yu FC, Hsu YH, Chen JH, Yang KC, Shih CH. Metabolic risk factors associated with erosive esophagitis. J Gastroenterol Hepatol. 2009 Aug; 24(8):1375-9.
    View in: PubMed
  14. Song Y, Hsu YH, Niu T, Manson JE, Buring JE, Liu S. Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women. BMC Med Genet. 2009; 10:4.
    View in: PubMed
  15. Liu CY, Hsu YH, Wu MT, Pan PC, Ho CK, Su L, Xu X, Li Y, Christiani DC. Cured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: a population based case-control study. BMC Cancer. 2009; 9:15.
    View in: PubMed
  16. Lee CC, You NC, Song Y, Hsu YH, Manson J, Nathan L, Tinker L, Liu S. Relation of genetic variation in the gene coding for C-reactive protein with its plasma protein concentrations: findings from the Women's Health Initiative Observational Cohort. Clin Chem. 2009 Feb; 55(2):351-60.
    View in: PubMed
  17. Song Y, You NC, Hsu YH, Howard BV, Langer RD, Manson JE, Nathan L, Niu T, F Tinker L, Liu S. FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women. Obesity (Silver Spring). 2008 Nov; 16(11):2472-80.
    View in: PubMed
  18. Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ. PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res. 2008 Sep; 23(9):1398-408.
    View in: PubMed
  19. Liu CY, Hsu YH, Pan PC, Wu MT, Ho CK, Su L, Xu X, Li Y, Christiani DC. Maternal and offspring genetic variants of AKR1C3 and the risk of childhood leukemia. Carcinogenesis. 2008 May; 29(5):984-90.
    View in: PubMed
  20. Hsu YH, Niu T, Song Y, Tinker L, Kuller LH, Liu S. Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study. Diabetes. 2008 Apr; 57(4):1101-7.
    View in: PubMed
  21. Song Y, You NC, Hsu YH, Sul J, Wang L, Tinker L, Eaton CB, Liu S. Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal women. Hum Mol Genet. 2007 Dec 1; 16(23):2960-71.
    View in: PubMed
  22. Hsu YH, Xu X, Terwedow HA, Niu T, Hong X, Wu D, Wang L, Brain JD, Bouxsein ML, Cummings SR, Rosen CJ, Xu X. Large-scale genome-wide linkage analysis for loci linked to BMD at different skeletal sites in extreme selected sibships. J Bone Miner Res. 2007 Feb; 22(2):184-94.
    View in: PubMed
  23. Hong X, Hsu YH, Terwedow H, Arguelles LM, Tang G, Liu X, Zhang S, Xu X, Xu X. CYP19A1 polymorphisms are associated with bone mineral density in Chinese men. Hum Genet. 2007 May; 121(3-4):491-500.
    View in: PubMed
  24. Hong X, Hsu YH, Terwedow H, Tang G, Liu X, Jiang S, Xu X, Xu X. Association of the methylenetetrahydrofolate reductase C677T polymorphism and fracture risk in Chinese postmenopausal women. Bone. 2007 Mar; 40(3):737-42.
    View in: PubMed
  25. Barrero LH, Hsu YH, Terwedow H, Perry MJ, Dennerlein JT, Brain JD, Xu X. Prevalence and physical determinants of low back pain in a rural Chinese population. Spine (Phila Pa 1976). 2006 Nov 1; 31(23):2728-34.
    View in: PubMed
  26. Zalloua PA, Hsu YH, Terwedow H, Zang T, Wu D, Tang G, Li Z, Hong X, Azar ST, Wang B, Bouxsein ML, Brain J, Cummings SR, Rosen CJ, Xu X. Impact of seafood and fruit consumption on bone mineral density. Maturitas. 2007 Jan 20; 56(1):1-11.
    View in: PubMed
  27. Hsu YH, Venners SA, Terwedow HA, Feng Y, Niu T, Li Z, Laird N, Brain JD, Cummings SR, Bouxsein ML, Rosen CJ, Xu X. Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr. 2006 Jan; 83(1):146-54.
    View in: PubMed
  28. Hsu YH, Niu T, Terwedow HA, Xu X, Feng Y, Li Z, Brain JD, Rosen CJ, Laird N, Xu X. Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men. Hum Genet. 2006 Jan; 118(5):568-77.
    View in: PubMed
  29. Feng Y, Hsu YH, Terwedow H, Chen Cz, Xu X, Niu T, Zang T, Wu D, Tang G, Li Z, Hong X, Wang B, Brain JD, Cummings SR, Rosen C, Bouxsein ML, Xu X. Familial aggregation of bone mineral density and bone mineral content in a Chinese population. Osteoporos Int. 2005 Dec; 16(12):1917-23.
    View in: PubMed
  30. Chen CJ, Hsu LI, Wang CH, Shih WL, Hsu YH, Tseng MP, Lin YC, Chou WL, Chen CY, Lee CY, Wang LH, Cheng YC, Chen CL, Chen SY, Wang YH, Hsueh YM, Chiou HY, Wu MM. Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan. Toxicol Appl Pharmacol. 2005 Aug 7; 206(2):198-206.
    View in: PubMed
  31. Jiang S, Hsu YH, Niu T, Xu X, Xing H, Chen C, Wang X, Zhang Y, Peng S, Xu X. A common haplotype on methylenetetrahydrofolate reductase gene modifies the effect of angiotensin-converting enzyme inhibitor on blood pressure in essential hypertension patients--a family-based association study. Clin Exp Hypertens. 2005 Aug; 27(6):509-21.
    View in: PubMed
  32. Jiang S, Hsu YH, Xu X, Xing H, Chen C, Niu T, Zhang Y, Peng S, Xu X. The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor. Thromb Res. 2004; 113(6):361-9.
    View in: PubMed
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