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Yaakov Nahmias, PH.D.

TitleInstructor in Surgery
InstitutionMassachusetts General Hospital
DepartmentSurgery
AddressShriners' Burn Institute
Center for Engineering in Medicine
51 Blossom St
Boston MA 02114
Phone617/371-4934
Fax617/371-4950

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Avior Y, Bomze D, Ramon O, Nahmias Y. Flavonoids as dietary regulators of nuclear receptor activity. Food Funct. 2013 Jun 28; 4(6):831-44.
    View in: PubMed
  2. Zhu B, Smith J, Yarmush ML, Nahmias Y, Kirby BJ, Murthy SK. Microfluidic enrichment of mouse epidermal stem cells and validation of stem cell proliferation in vitro. Tissue Eng Part C Methods. 2013 Oct; 19(10):765-73.
    View in: PubMed
  3. Ezra E, Keinan E, Mandel Y, Boulton ME, Nahmias Y. Non-dimensional analysis of retinal microaneurysms: critical threshold for treatment. Integr Biol (Camb). 2013 Feb 25; 5(3):474-80.
    View in: PubMed
  4. Shulman M, Nahmias Y. Long-term culture and coculture of primary rat and human hepatocytes. Methods Mol Biol. 2013; 945:287-302.
    View in: PubMed
  5. Spokoini R, Moldavski O, Nahmias Y, England JL, Schuldiner M, Kaganovich D. Confinement to organelle-associated inclusion structures mediates asymmetric inheritance of aggregated protein in budding yeast. Cell Rep. 2012 Oct 25; 2(4):738-47.
    View in: PubMed
  6. Bao J, Fisher JE, Lillegard JB, Wang W, Amiot B, Yu Y, Dietz AB, Nahmias Y, Nyberg SL. Serum-free medium and mesenchymal stromal cells enhance functionality and stabilize integrity of rat hepatocyte spheroids. Cell Transplant. 2013; 22(2):299-308.
    View in: PubMed
  7. Roelandt P, Obeid S, Paeshuyse J, Vanhove J, Van Lommel A, Nahmias Y, Nevens F, Neyts J, Verfaillie CM. Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus. J Hepatol. 2012 Aug; 57(2):246-51.
    View in: PubMed
  8. Nevo-Yassaf I, Yaffe Y, Asher M, Ravid O, Eizenberg S, Henis YI, Nahmias Y, Hirschberg K, Sklan EH. Role for TBC1D20 and Rab1 in hepatitis C virus replication via interaction with lipid droplet-bound nonstructural protein 5A. J Virol. 2012 Jun; 86(12):6491-502.
    View in: PubMed
  9. Merquiol E, Uzi D, Mueller T, Goldenberg D, Nahmias Y, Xavier RJ, Tirosh B, Shibolet O. HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response. PLoS One. 2011; 6(9):e24660.
    View in: PubMed
  10. Shulman M, Cohen M, Soto-Gutierrez A, Yagi H, Wang H, Goldwasser J, Lee-Parsons CW, Benny-Ratsaby O, Yarmush ML, Nahmias Y. Enhancement of naringenin bioavailability by complexation with hydroxypropoyl-ß-cyclodextrin. PLoS One. 2011; 6(4):e18033.
    View in: PubMed
  11. Goldwasser J, Cohen PY, Lin W, Kitsberg D, Balaguer P, Polyak SJ, Chung RT, Yarmush ML, Nahmias Y. Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. J Hepatol. 2011 Nov; 55(5):963-71.
    View in: PubMed
  12. Koria P, Yagi H, Kitagawa Y, Megeed Z, Nahmias Y, Sheridan R, Yarmush ML. Self-assembling elastin-like peptides growth factor chimeric nanoparticles for the treatment of chronic wounds. Proc Natl Acad Sci U S A. 2011 Jan 18; 108(3):1034-9.
    View in: PubMed
  13. Izamis ML, Sharma NS, Uygun B, Bieganski R, Saeidi N, Nahmias Y, Uygun K, Yarmush ML, Berthiaume F. In situ metabolic flux analysis to quantify the liver metabolic response to experimental burn injury. Biotechnol Bioeng. 2011 Apr; 108(4):839-52.
    View in: PubMed
  14. Goldwasser J, Cohen PY, Yang E, Balaguer P, Yarmush ML, Nahmias Y. Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha. PLoS One. 2010; 5(8):e12399.
    View in: PubMed
  15. Yagi H, Soto-Gutierrez A, Navarro-Alvarez N, Nahmias Y, Goldwasser Y, Kitagawa Y, Tilles AW, Tompkins RG, Parekkadan B, Yarmush ML. Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1. Mol Ther. 2010 Oct; 18(10):1857-64.
    View in: PubMed
  16. Uygun BE, Soto-Gutierrez A, Yagi H, Izamis ML, Guzzardi MA, Shulman C, Milwid J, Kobayashi N, Tilles A, Berthiaume F, Hertl M, Nahmias Y, Yarmush ML, Uygun K. Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix. Nat Med. 2010 Jul; 16(7):814-20.
    View in: PubMed
  17. Wagoner J, Negash A, Kane OJ, Martinez LE, Nahmias Y, Bourne N, Owen DM, Grove J, Brimacombe C, McKeating JA, Pécheur EI, Graf TN, Oberlies NH, Lohmann V, Cao F, Tavis JE, Polyak SJ. Multiple effects of silymarin on the hepatitis C virus lifecycle. Hepatology. 2010 Jun; 51(6):1912-21.
    View in: PubMed
  18. Maguire TJ, Novik E, Chao P, Barminko J, Nahmias Y, Yarmush ML, Cheng KC. Design and application of microfluidic systems for in vitro pharmacokinetic evaluation of drug candidates. Curr Drug Metab. 2009 Dec; 10(10):1192-9.
    View in: PubMed
  19. Kidambi S, Yarmush RS, Novik E, Chao P, Yarmush ML, Nahmias Y. Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15714-9.
    View in: PubMed
  20. Kidambi S, Yarmush J, Fong W, Kamath S, Schianodicola J, Nahmias Y. Propofol induces ERK-dependant expression of c-Fos and Egr-1 in neuronal cells. Neuroreport. 2009 May 6; 20(7):657-62.
    View in: PubMed
  21. Jindal R, Nahmias Y, Tilles AW, Berthiaume F, Yarmush ML. Amino acid-mediated heterotypic interaction governs performance of a hepatic tissue model. FASEB J. 2009 Jul; 23(7):2288-98.
    View in: PubMed
  22. Tolboom H, Pouw RE, Izamis ML, Milwid JM, Sharma N, Soto-Gutierrez A, Nahmias Y, Uygun K, Berthiaume F, Yarmush ML. Recovery of warm ischemic rat liver grafts by normothermic extracorporeal perfusion. Transplantation. 2009 Jan 27; 87(2):170-7.
    View in: PubMed
  23. Song Q, Risco R, Latina M, Berthiaume F, Nahmias Y, Yarmush ML. Selective targeting of pigmented retinal pigment epithelial (RPE) cells by a single pulsed laser irradiation: an in vitro study. Opt Express. 2008 Jul 7; 16(14):10518-28.
    View in: PubMed
  24. Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, Adini I, Pravda E, Nahmias Y, Koirala S, Corfas G, D'Amato RJ, Folkman J. An orally delivered small-molecule formulation with antiangiogenic and anticancer activity. Nat Biotechnol. 2008 Jul; 26(7):799-807.
    View in: PubMed
  25. van Poll D, Parekkadan B, Cho CH, Berthiaume F, Nahmias Y, Tilles AW, Yarmush ML. Mesenchymal stem cell-derived molecules directly modulate hepatocellular death and regeneration in vitro and in vivo. Hepatology. 2008 May; 47(5):1634-43.
    View in: PubMed
  26. Nahmias Y, Goldwasser J, Casali M, van Poll D, Wakita T, Chung RT, Yarmush ML. Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin. Hepatology. 2008 May; 47(5):1437-45.
    View in: PubMed
  27. Parashurama N, Nahmias Y, Cho CH, van Poll D, Tilles AW, Berthiaume F, Yarmush ML. Activin alters the kinetics of endoderm induction in embryonic stem cells cultured on collagen gels. Stem Cells. 2008 Feb; 26(2):474-84.
    View in: PubMed
  28. Cho CH, Parashurama N, Park EY, Suganuma K, Nahmias Y, Park J, Tilles AW, Berthiaume F, Yarmush ML. Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells: applications for the treatment of liver failure. FASEB J. 2008 Mar; 22(3):898-909.
    View in: PubMed
  29. Nahmias Y, Berthiaume F, Yarmush ML. Integration of technologies for hepatic tissue engineering. Adv Biochem Eng Biotechnol. 2007; 103:309-29.
    View in: PubMed
  30. Nahmias Y, Kramvis Y, Barbe L, Casali M, Berthiaume F, Yarmush ML. A novel formulation of oxygen-carrying matrix enhances liver-specific function of cultured hepatocytes. FASEB J. 2006 Dec; 20(14):2531-3.
    View in: PubMed
  31. Nahmias Y, Schwartz RE, Hu WS, Verfaillie CM, Odde DJ. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro. Tissue Eng. 2006 Jun; 12(6):1627-38.
    View in: PubMed
  32. Nahmias Y, Casali M, Barbe L, Berthiaume F, Yarmush ML. Liver endothelial cells promote LDL-R expression and the uptake of HCV-like particles in primary rat and human hepatocytes. Hepatology. 2006 Feb; 43(2):257-65.
    View in: PubMed
  33. Nahmias Y, Odde DJ. Micropatterning of living cells by laser-guided direct writing: application to fabrication of hepatic-endothelial sinusoid-like structures. Nat Protoc. 2006; 1(5):2288-96.
    View in: PubMed
  34. Nahmias Y, Schwartz RE, Verfaillie CM, Odde DJ. Laser-guided direct writing for three-dimensional tissue engineering. Biotechnol Bioeng. 2005 Oct 20; 92(2):129-36.
    View in: PubMed
  35. Nahmias Y, Arneja A, Tower TT, Renn MJ, Odde DJ. Cell patterning on biological gels via cell spraying through a mask. Tissue Eng. 2005 May-Jun; 11(5-6):701-8.
    View in: PubMed
  36. Nahmias YK, Gao BZ, Odde DJ. Dimensionless parameters for the design of optical traps and laser guidance systems. Appl Opt. 2004 Jul 10; 43(20):3999-4006.
    View in: PubMed
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