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John Ioannidis, Ph.D., M.D.

TitleAdjunct Professor of Epidemiology
InstitutionHarvard School of Public Health
DepartmentEpidemiology
AddressHarvard School of Public Health
Kresge Bldg, 9th Floor
677 Huntington Ave
Boston MA 02115

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ioannidis JP. Are mortality differences detected by administrative data reliable and actionable? JAMA. 2013 Apr 3; 309(13):1410-1.
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  2. Ioannidis JP. Informed consent, big data, and the oxymoron of research that is not research. Am J Bioeth. 2013 Apr; 13(4):40-2.
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  3. Morris AH, Ioannidis JP. Limitations of medical research and evidence at the patient-clinician encounter scale. Chest. 2013 Apr 1; 143(4):1127-35.
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  4. Ioannidis JP. This I believe in genetics: discovery can be a nuisance, replication is science, implementation matters. Front Genet. 2013; 4:33.
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  5. McDonald KM, Matesic B, Contopoulos-Ioannidis DG, Lonhart J, Schmidt E, Pineda N, Ioannidis JP. Patient safety strategies targeted at diagnostic errors: a systematic review. Ann Intern Med. 2013 Mar 5; 158(5 Pt 2):381-9.
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  6. Khoury MJ, Lam TK, Ioannidis JP, Hartge P, Spitz MR, Buring JE, Chanock SJ, Croyle RT, Goddard KA, Ginsburg GS, Herceg Z, Hiatt RA, Hoover RN, Hunter DJ, Kramer BS, Lauer MS, Meyerhardt JA, Olopade OI, Palmer JR, Sellers TA, Seminara D, Ransohoff DF, Rebbeck TR, Tourassi G, Winn DM, Zauber A, Schully SD. Transforming epidemiology for 21st century medicine and public health. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):508-16.
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  7. Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Saïd S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Léveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013 Apr; 45(4):433-9.
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  8. Ioannidis JP, Pereira TV, Horwitz RI. Emergence of large treatment effects from small trials--reply. JAMA. 2013 Feb 27; 309(8):768-9.
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  9. Panagiotou OA, Contopoulos-Ioannidis DG, Ioannidis JP. Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment. BMJ. 2013; 346:f707.
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  10. Stefanaki I, Panagiotou OA, Kodela E, Gogas H, Kypreou KP, Chatzinasiou F, Nikolaou V, Plaka M, Kalfa I, Antoniou C, Ioannidis JP, Evangelou E, Stratigos AJ. Replication and Predictive Value of SNPs Associated with Melanoma and Pigmentation Traits in a Southern European Case-Control Study. PLoS One. 2013; 8(2):e55712.
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  11. Haidich AB, Pilalas D, Contopoulos-Ioannidis DG, Ioannidis JP. Most meta-analyses of drug interventions have narrow scopes and many focus on specific agents. J Clin Epidemiol. 2013 Apr; 66(4):371-8.
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  12. Prasad V, Jorgenson J, Ioannidis JP, Cifu A. Observational studies often make clinical practice recommendations: an empirical evaluation of authors' attitudes. J Clin Epidemiol. 2013 Apr; 66(4):361-366.e4.
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  13. Broer L, Lill CM, Schuur M, Amin N, Roehr JT, Bertram L, Ioannidis JP, van Duijn CM. Distinguishing true from false positives in genomic studies: p values. Eur J Epidemiol. 2013 Feb; 28(2):131-8.
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  14. Ioannidis JP. Mega-trials for blockbusters. JAMA. 2013 Jan 16; 309(3):239-40.
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  15. Ioannidis JP, Nicholson JM. NIH funding: The critics respond. Nature. 2013 Jan 3; 493(7430):26.
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  16. Verma M, Khoury MJ, Ioannidis JP. Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling. Cancer Epidemiol Biomarkers Prev. 2013 Feb; 22(2):189-200.
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  17. Ioannidis JP, Nosek B, Iorns E. Reproducibility concerns. Nat Med. 2012 Dec 6; 18(12):1736-7.
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  18. Nicholson JM, Ioannidis JP. Research grants: Conform and be funded. Nature. 2012 Dec 4; 492(7427):34-6.
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  19. Schoenfeld JD, Ioannidis JP. Is everything we eat associated with cancer? A systematic cookbook review. Am J Clin Nutr. 2013 Jan; 97(1):127-34.
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  20. Ioannidis JP. There is nothing personal-reply. Arch Intern Med. 2012 Nov 26; 172(21):1691-2.
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  21. Staines-Urias E, Paez MC, Doyle P, Dudbridge F, Serrano NC, Ioannidis JP, Keating BJ, Hingorani AD, Casas JP. Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis. Int J Epidemiol. 2012 Dec; 41(6):1764-75.
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  22. Ioannidis JP, Yu Y, Seddon JM. To Correct or Not to Correct-and How. Epidemiology. 2012 Nov; 23(6):912-3.
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  23. Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Bertram L, Bozi M, Barcikowska M, Crosiers D, Clarke CE, Facheris MF, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon BS, Jamrozik Z, Krygowska-Wajs A, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Libioulle C, Murata M, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Meitnger T, Zimprich A, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Strom TM, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Van Broeckhoven C, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yomono HS, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R. A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants. J Med Genet. 2012 Nov; 49(11):721-6.
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  24. Gøtzsche PC, Ioannidis JP. Content area experts as authors: helpful or harmful for systematic reviews and meta-analyses? BMJ. 2012; 345:e7031.
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  25. Ioannidis JP, Yu Y, Seddon JM. Correction of phenotype misclassification based on high-discrimination genetic predictive risk models. Epidemiology. 2012 Nov; 23(6):902-9.
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  26. Katritsis DG, Siontis KC, Bigger JT, Kadish AH, Steinman R, Zareba W, Siontis GC, Bardy GH, Ioannidis JP. Effect of left ventricular ejection fraction and QRS duration on the survival benefit of implantable cardioverter-defibrillators: Meta-analysis of primary prevention trials. Heart Rhythm. 2013 Feb; 10(2):200-6.
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  27. Aljasir B, Ioannidis JP, Yurkiewich A, Moher D, Higgins JP, Arora P, Little J. Assessment of systematic effects of methodological characteristics on candidate genetic associations. Hum Genet. 2013 Feb; 132(2):167-78.
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  28. Pereira TV, Horwitz RI, Ioannidis JP. Empirical evaluation of very large treatment effects of medical interventions. JAMA. 2012 Oct 24; 308(16):1676-84.
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  29. Ioannidis JP, Schully SD, Lam TK, Khoury MJ. Knowledge integration in cancer: current landscape and future prospects. Cancer Epidemiol Biomarkers Prev. 2013 Jan; 22(1):3-10.
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  30. Tzoulaki I, Patel CJ, Okamura T, Chan Q, Brown IJ, Miura K, Ueshima H, Zhao L, Van Horn L, Daviglus ML, Stamler J, Butte AJ, Ioannidis JP, Elliott P. A nutrient-wide association study on blood pressure. Circulation. 2012 Nov 20; 126(21):2456-64.
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  31. Tsilidis KK, Papatheodorou SI, Evangelou E, Ioannidis JP. Evaluation of Excess Statistical Significance in Meta-analyses of 98 Biomarker Associations with Cancer Risk. J Natl Cancer Inst. 2012 Dec 19; 104(24):1867-78.
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  32. Kappagoda S, Ioannidis JP. Neglected tropical diseases: survey and geometry of randomised evidence. BMJ. 2012; 345:e6512.
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  33. Ioannidis JP. Scientific inbreeding and same-team replication: Type D personality as an example. J Psychosom Res. 2012 Dec; 73(6):408-10.
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  34. Mischak H, Vlahou A, Ioannidis JP. Technical aspects and inter-laboratory variability in native peptide profiling: The CE-MS experience. Clin Biochem. 2013 Apr; 46(6):432-43.
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  35. Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, Minster RL, Carless MA, Kammerer CM, Oei L, Zhou Y, Alonso N, Dailiana Z, Eriksson J, García-Giralt N, Giroux S, Husted LB, Khusainova RI, Koromila T, Kung AW, Lewis JR, Masi L, Mencej-Bedrac S, Nogues X, Patel MS, Prezelj J, Richards JB, Sham PC, Spector T, Vandenput L, Xiao SM, Zheng HF, Zhu K, Balcells S, Brandi ML, Frost M, Goltzman D, González-Macías J, Karlsson M, Khusnutdinova EK, Kollia P, Langdahl BL, Ljunggren O, Lorentzon M, Marc J, Mellström D, Ohlsson C, Olmos JM, Ralston SH, Riancho JA, Rousseau F, Urreizti R, Van Hul W, Zarrabeitia MT, Castano-Betancourt M, Demissie S, Grundberg E, Herrera L, Kwan T, Medina-Gómez C, Pastinen T, Sigurdsson G, Thorleifsson G, Vanmeurs JB, Blangero J, Hofman A, Liu Y, Mitchell BD, O'Connell JR, Oostra BA, Rotter JI, Stefansson K, Streeten EA, Styrkarsdottir U, Thorsteinsdottir U, Tylavsky FA, Uitterlinden A, Cauley JA, Harris TB, Ioannidis JP, Psaty BM, Robbins JA, Zillikens MC, Vanduijn CM, Prince RL, Karasik D, Rivadeneira F, Kiel DP, Cupples LA, Hsu YH. Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res. 2012 Oct; 27(10):2051-64.
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  36. Mills EJ, Ioannidis JP, Thorlund K, Schünemann HJ, Puhan MA, Guyatt GH. How to use an article reporting a multiple treatment comparison meta-analysis. JAMA. 2012 Sep 26; 308(12):1246-53.
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  37. Ioannidis JP. Biomarker failures. Clin Chem. 2013 Jan; 59(1):202-4.
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  38. Savovic J, Jones HE, Altman DG, Harris RJ, Jüni P, Pildal J, Als-Nielsen B, Balk EM, Gluud C, Gluud LL, Ioannidis JP, Schulz KF, Beynon R, Welton NJ, Wood L, Moher D, Deeks JJ, Sterne JA. Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials. Ann Intern Med. 2012 Sep 18; 157(6):429-38.
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  39. Mills EJ, Thorlund K, Ioannidis JP. Calculating additive treatment effects from multiple randomized trials provides useful estimates of combination therapies. J Clin Epidemiol. 2012 Dec; 65(12):1282-8.
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  40. Ioannidis JP. Extrapolating from animals to humans. Sci Transl Med. 2012 Sep 12; 4(151):151ps15.
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  41. Evangelou E, Siontis KC, Pfeiffer T, Ioannidis JP. Perceived information gain from randomized trials correlates with publication in high-impact factor journals. J Clin Epidemiol. 2012 Dec; 65(12):1274-81.
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  42. Zintzaras E, Ioannidis JP. METRADISC-XL: A program for meta-analysis of multidimensional ranked discovery oriented datasets including microarrays. Comput Methods Programs Biomed. 2012 Dec; 108(3):1243-6.
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  43. Erhardt A, Akula N, Schumacher J, Czamara D, Karbalai N, Müller-Myhsok B, Mors O, Borglum A, Kristensen AS, Woldbye DP, Koefoed P, Eriksson E, Maron E, Metspalu A, Nurnberger J, Philibert RA, Kennedy J, Domschke K, Reif A, Deckert J, Otowa T, Kawamura Y, Kaiya H, Okazaki Y, Tanii H, Tokunaga K, Sasaki T, Ioannidis JP, McMahon FJ, Binder EB. Replication and meta-analysis of TMEM132D gene variants in panic disorder. Transl Psychiatry. 2012; 2:e156.
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  44. Ioannidis JP. The importance of potential studies that have not existed and registration of observational data sets. JAMA. 2012 Aug 8; 308(6):575-6.
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  45. Bertsias GK, Tektonidou M, Amoura Z, Aringer M, Bajema I, Berden JH, Boletis J, Cervera R, Dörner T, Doria A, Ferrario F, Floege J, Houssiau FA, Ioannidis JP, Isenberg DA, Kallenberg CG, Lightstone L, Marks SD, Martini A, Moroni G, Neumann I, Praga M, Schneider M, Starra A, Tesar V, Vasconcelos C, van Vollenhoven RF, Zakharova H, Haubitz M, Gordon C, Jayne D, Boumpas DT. Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis. 2012 Nov; 71(11):1771-82.
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  46. Bourgeois FT, Murthy S, Pinto C, Olson KL, Ioannidis JP, Mandl KD. Pediatric versus adult drug trials for conditions with high pediatric disease burden. Pediatrics. 2012 Aug; 130(2):285-92.
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  47. Orozco G, Ioannidis JP, Morris A, Zeggini E. Sex-specific differences in effect size estimates at established complex trait loci. Int J Epidemiol. 2012 Oct; 41(5):1376-82.
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  48. Doufas AG, Panagiotou OA, Ioannidis JP. Concordance of sleep and pain outcomes of diverse interventions: an umbrella review. PLoS One. 2012; 7(7):e40891.
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  49. Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Van Broeckhoven C, Bertram L, Bozi M, Crosiers D, Clarke C, Facheris M, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon B, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R. Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology. 2012 Aug 14; 79(7):659-67.
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  50. Manzoli L, Ioannidis JP, Flacco ME, De Vito C, Villari P. Effectiveness and harms of seasonal and pandemic influenza vaccines in children, adults and elderly: a critical review and re-analysis of 15 meta-analyses. Hum Vaccin Immunother. 2012 Jul; 8(7):851-62.
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  51. Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, Zack DJ, Campochiaro P, Smith RT, Barile GR, Hogg RE, Chakravarthy U, Behrens TW, Uitterlinden AG, van Duijn CM, Vingerling JR, Brantley MA, Baird PN, Klaver CC, Allikmets R, Katsanis N, Graham RR, Ioannidis JP, Daly MJ, Seddon JM. Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Ophthalmology. 2012 Sep; 119(9):1874-85.
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  52. Contopoulos-Ioannidis DG, Seto I, Hamm MP, Thomson D, Hartling L, Ioannidis JP, Curtis S, Constantin E, Batmanabane G, Klassen T, Williams K. Empirical evaluation of age groups and age-subgroup analyses in pediatric randomized trials and pediatric meta-analyses. Pediatrics. 2012 Jun; 129 Suppl 3:S161-84.
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  53. Williams K, Thomson D, Seto I, Contopoulos-Ioannidis DG, Ioannidis JP, Curtis S, Constantin E, Batmanabane G, Hartling L, Klassen T. Standard 6: age groups for pediatric trials. Pediatrics. 2012 Jun; 129 Suppl 3:S153-60.
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  54. Knowles JW, Assimes TL, Kiernan M, Pavlovic A, Goldstein BA, Yank V, McConnell MV, Absher D, Bustamante C, Ashley EA, Ioannidis JP. Randomized trial of personal genomics for preventive cardiology: design and challenges. Circ Cardiovasc Genet. 2012 Jun; 5(3):368-76.
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  55. Siontis GC, Tzoulaki I, Siontis KC, Ioannidis JP. Comparisons of established risk prediction models for cardiovascular disease: systematic review. BMJ. 2012; 344:e3318.
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  56. Boffetta P, Winn DM, Ioannidis JP, Thomas DC, Little J, Smith GD, Cogliano VJ, Hecht SS, Seminara D, Vineis P, Khoury MJ. Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans. Int J Epidemiol. 2012 Jun; 41(3):686-704.
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  57. Ioannidis JP. Invited commentary-Genetic prediction for common diseases. Arch Intern Med. 2012 May 14; 172(9):744-6.
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  58. Panagiotou OA, Ioannidis JP. Primary study authors of significant studies are more likely to believe that a strong association exists in a heterogeneous meta-analysis compared with methodologists. J Clin Epidemiol. 2012 Jul; 65(7):740-7.
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  59. Mischak H, Ioannidis JP, Argiles A, Attwood TK, Bongcam-Rudloff E, Broenstrup M, Charonis A, Chrousos GP, Delles C, Dominiczak A, Dylag T, Ehrich J, Egido J, Findeisen P, Jankowski J, Johnson RW, Julien BA, Lankisch T, Leung HY, Maahs D, Magni F, Manns MP, Manolis E, Mayer G, Navis G, Novak J, Ortiz A, Persson F, Peter K, Riese HH, Rossing P, Sattar N, Spasovski G, Thongboonkerd V, Vanholder R, Schanstra JP, Vlahou A. Implementation of proteomic biomarkers: making it work. Eur J Clin Invest. 2012 Sep; 42(9):1027-36.
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  60. Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-Gómez C, Palsson ST, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtimäki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet. 2012 May; 44(5):491-501.
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  61. Ioannidis JP. Are medical conferences useful? And for whom? JAMA. 2012 Mar 28; 307(12):1257-8.
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  62. Lill CM, Roehr JT, McQueen MB, Kavvoura FK, Bagade S, Schjeide BM, Schjeide LM, Meissner E, Zauft U, Allen NC, Liu T, Schilling M, Anderson KJ, Beecham G, Berg D, Biernacka JM, Brice A, DeStefano AL, Do CB, Eriksson N, Factor SA, Farrer MJ, Foroud T, Gasser T, Hamza T, Hardy JA, Heutink P, Hill-Burns EM, Klein C, Latourelle JC, Maraganore DM, Martin ER, Martinez M, Myers RH, Nalls MA, Pankratz N, Payami H, Satake W, Scott WK, Sharma M, Singleton AB, Stefansson K, Toda T, Tung JY, Vance J, Wood NW, Zabetian CP, Young P, Tanzi RE, Khoury MJ, Zipp F, Lehrach H, Ioannidis JP, Bertram L. Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet. 2012; 8(3):e1002548.
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  63. Patel CJ, Cullen MR, Ioannidis JP, Butte AJ. Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels. Int J Epidemiol. 2012 Jun; 41(3):828-43.
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  64. Nair VS, Maeda LS, Ioannidis JP. Clinical outcome prediction by microRNAs in human cancer: a systematic review. J Natl Cancer Inst. 2012 Apr 4; 104(7):528-40.
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  65. Ioannidis JP, Tzoulaki I. Minimal and null predictive effects for the most popular blood biomarkers of cardiovascular disease. Circ Res. 2012 Mar 2; 110(5):658-62.
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  66. Moonesinghe R, Ioannidis JP, Flanders WD, Yang Q, Truman BI, Khoury MJ. Estimating the contribution of genetic variants to difference in incidence of disease between population groups. Eur J Hum Genet. 2012 Aug; 20(8):831-6.
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  67. Prasad V, Cifu A, Ioannidis JP. Reversals of established medical practices: evidence to abandon ship. JAMA. 2012 Jan 4; 307(1):37-8.
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  68. Ntzani EE, Liberopoulos G, Manolio TA, Ioannidis JP. Consistency of genome-wide associations across major ancestral groups. Hum Genet. 2012 Jul; 131(7):1057-71.
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  69. Panagiotou OA, Ioannidis JP. What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations. Int J Epidemiol. 2012 Feb; 41(1):273-86.
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  70. Smit Y, Huibers MJ, Ioannidis JP, van Dyck R, van Tilburg W, Arntz A. The effectiveness of long-term psychoanalytic psychotherapy--a meta-analysis of randomized controlled trials. Clin Psychol Rev. 2012 Mar; 32(2):81-92.
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  71. Ioannidis JP, Manzoli L, De Vito C, D'Addario M, Villari P. Publication delay of randomized trials on 2009 influenza A (H1N1) vaccination. PLoS One. 2011; 6(12):e28346.
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  72. Ioannidis JP, Khoury MJ. Improving validation practices in "omics" research. Science. 2011 Dec 2; 334(6060):1230-2.
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  77. Gallo V, Egger M, McCormack V, Farmer PB, Ioannidis JP, Kirsch-Volders M, Matullo G, Phillips DH, Schoket B, Stromberg U, Vermeulen R, Wild C, Porta M, Vineis P. STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology (STROBE-ME): an extension of the STROBE Statement. PLoS Med. 2011 Oct; 8(10):e1001117.
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  78. Gallo V, Egger M, McCormack V, Farmer PB, Ioannidis JP, Kirsch-Volders M, Matullo G, Phillips DH, Schoket B, Stromberg U, Vermeulen R, Wild C, Porta M, Vineis P. STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement. Mutagenesis. 2012 Jan; 27(1):17-29.
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  79. Gallo V, Egger M, McCormack V, Farmer PB, Ioannidis JP, Kirsch-Volders M, Matullo G, Phillips DH, Schoket B, Stromberg U, Vermeulen R, Wild C, Porta M, Vineis P. STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement. Eur J Clin Invest. 2012 Jan; 42(1):1-16.
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  80. Gallo V, Egger M, McCormack V, Farmer PB, Ioannidis JP, Kirsch-Volders M, Matullo G, Phillips DH, Schoket B, Stromberg U, Vermeulen R, Wild C, Porta M, Vineis P. STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement. Prev Med. 2011 Dec; 53(6):377-87.
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  81. Gallo V, Egger M, McCormack V, Farmer PB, Ioannidis JP, Kirsch-Volders M, Matullo G, Phillips DH, Schoket B, Stromberg U, Vermeulen R, Wild C, Porta M, Vineis P. STrengthening the Reporting of OBservational studies in Epidemiology: Molecular Epidemiology STROBE-ME. An extension of the STROBE statement. J Epidemiol Community Health. 2012 Sep; 66(9):844-54.
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  82. Ioannidis JP. More time for research: fund people not projects. Nature. 2011 Sep 29; 477(7366):529-31.
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  83. Thombs BD, Coyne JC, Cuijpers P, de Jonge P, Gilbody S, Ioannidis JP, Johnson BT, Patten SB, Turner EH, Ziegelstein RC. Rethinking recommendations for screening for depression in primary care. CMAJ. 2012 Mar 6; 184(4):413-8.
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  84. Siontis KC, Evangelou E, Ioannidis JP. Magnitude of effects in clinical trials published in high-impact general medical journals. Int J Epidemiol. 2011 Oct; 40(5):1280-91.
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  85. Alsheikh-Ali AA, Qureshi W, Al-Mallah MH, Ioannidis JP. Public availability of published research data in high-impact journals. PLoS One. 2011; 6(9):e24357.
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  86. Manzoli L, De Vito C, Salanti G, D'Addario M, Villari P, Ioannidis JP. Meta-analysis of the immunogenicity and tolerability of pandemic influenza A 2009 (H1N1) vaccines. PLoS One. 2011; 6(9):e24384.
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  87. Contopoulos-Ioannidis DG, Ioannidis JP. Claims for improved survival from systemic corticosteroids in diverse conditions: an umbrella review. Eur J Clin Invest. 2012 Mar; 42(3):233-44.
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  88. Ross OA, Soto-Ortolaza AI, Heckman MG, Aasly JO, Abahuni N, Annesi G, Bacon JA, Bardien S, Bozi M, Brice A, Brighina L, Van Broeckhoven C, Carr J, Chartier-Harlin MC, Dardiotis E, Dickson DW, Diehl NN, Elbaz A, Ferrarese C, Ferraris A, Fiske B, Gibson JM, Gibson R, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lesage S, Lin CH, Lynch T, Maraganore DM, Mellick GD, Mutez E, Nilsson C, Opala G, Park SS, Puschmann A, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Theuns J, Tomiyama H, Uitti RJ, Valente EM, van de Loo S, Vassilatis DK, Vilariño-Güell C, White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Farrer MJ. Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study. Lancet Neurol. 2011 Oct; 10(10):898-908.
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  89. Siontis GC, Tzoulaki I, Ioannidis JP. Predicting death: an empirical evaluation of predictive tools for mortality. Arch Intern Med. 2011 Oct 24; 171(19):1721-6.
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  90. Sharma M, Maraganore DM, Ioannidis JP, Riess O, Aasly JO, Annesi G, Abahuni N, Bentivoglio AR, Brice A, Van Broeckhoven C, Chartier-Harlin MC, Destée A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Gispert S, Hattori N, Jasinska-Myga B, Klein C, Lesage S, Lynch T, Lichtner P, Lambert JC, Lang AE, Mellick GD, De Nigris F, Opala G, Quattrone A, Riva C, Rogaeva E, Ross OA, Satake W, Silburn PA, Theuns J, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Gasser T, Krüger R. Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease. Neurobiol Aging. 2011 Nov; 32(11):2108.e1-5.
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  91. Sterne JA, Sutton AJ, Ioannidis JP, Terrin N, Jones DR, Lau J, Carpenter J, Rücker G, Harbord RM, Schmid CH, Tetzlaff J, Deeks JJ, Peters J, Macaskill P, Schwarzer G, Duval S, Altman DG, Moher D, Higgins JP. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ. 2011; 343:d4002.
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  92. Ioannidis JP, Garber AM. Individualized cost-effectiveness analysis. PLoS Med. 2011 Jul; 8(7):e1001058.
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  93. Siontis GC, Ioannidis JP. Risk factors and interventions with statistically significant tiny effects. Int J Epidemiol. 2011 Oct; 40(5):1292-307.
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  94. Ioannidis JP, Tarone R, McLaughlin JK. The false-positive to false-negative ratio in epidemiologic studies. Epidemiology. 2011 Jul; 22(4):450-6.
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  95. Chatzinasiou F, Lill CM, Kypreou K, Stefanaki I, Nicolaou V, Spyrou G, Evangelou E, Roehr JT, Kodela E, Katsambas A, Tsao H, Ioannidis JP, Bertram L, Stratigos AJ. Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma. J Natl Cancer Inst. 2011 Aug 17; 103(16):1227-35.
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  96. Papatheodorou SI, Evangelou E, Makrydimas G, Ioannidis JP. First-trimester ductus venosus screening for cardiac defects: a meta-analysis. BJOG. 2011 Nov; 118(12):1438-45.
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  97. Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, Lee PH, Lee AY, Leveziel N, Zack DJ, Campochiaro B, Campochiaro P, Smith RT, Barile GR, Guymer RH, Hogg R, Chakravarthy U, Robman LD, Gustafsson O, Sigurdsson H, Ortmann W, Behrens TW, Stefansson K, Uitterlinden AG, van Duijn CM, Vingerling JR, Klaver CC, Allikmets R, Brantley MA, Baird PN, Katsanis N, Thorsteinsdottir U, Ioannidis JP, Daly MJ, Graham RR, Seddon JM. Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet. 2011 Sep 15; 20(18):3699-709.
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  98. Ioannidis JP. An epidemic of false claims. Competition and conflicts of interest distort too many medical findings. Sci Am. 2011 Jun; 304(6):16.
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  99. Ioannidis JP, Panagiotou OA. Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses. JAMA. 2011 Jun 1; 305(21):2200-10.
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  100. Polyzos NP, Mauri D, Ioannidis JP. Guidelines on chemotherapy in advanced stage gynecological malignancies: an evaluation of 224 professional societies and organizations. PLoS One. 2011; 6(5):e20106.
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  101. Zhu YG, Ioannidis JP, Li H, Jones KC, Martin FL. Understanding and harnessing the health effects of rapid urbanization in China. Environ Sci Technol. 2011 Jun 15; 45(12):5099-104.
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  102. Bonitsis NG, Tatsioni A, Bassioukas K, Ioannidis JP. Allergens responsible for allergic contact dermatitis among children: a systematic review and meta-analysis. Contact Dermatitis. 2011 May; 64(5):245-57.
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  103. Sigounas DE, Tatsioni A, Christodoulou DK, Tsianos EV, Ioannidis JP. New prognostic markers for outcome of acute pancreatitis: overview of reporting in 184 studies. Pancreas. 2011 May; 40(4):522-32.
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  104. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Hum Genet. 2011 May; 19(5):18 p preceding 494.
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  105. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of Genetic Risk Prediction Studies: the GRIPS statement. Genet Med. 2011 May; 13(5):453-6.
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  106. Ioannidis JP. A roadmap for successful applications of clinical proteomics. Proteomics Clin Appl. 2011 Jun; 5(5-6):241-7.
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  107. Evangelou E, Fellay J, Colombo S, Martinez-Picado J, Obel N, Goldstein DB, Telenti A, Ioannidis JP. Impact of phenotype definition on genome-wide association signals: empirical evaluation in human immunodeficiency virus type 1 infection. Am J Epidemiol. 2011 Jun 1; 173(11):1336-42.
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  108. Ioannidis JP. Excess significance bias in the literature on brain volume abnormalities. Arch Gen Psychiatry. 2011 Aug; 68(8):773-80.
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  110. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Epidemiol. 2011 Apr; 26(4):313-37.
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  111. Pereira TV, Ioannidis JP. Statistically significant meta-analyses of clinical trials have modest credibility and inflated effects. J Clin Epidemiol. 2011 Oct; 64(10):1060-9.
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  112. Pfeiffer T, Bertram L, Ioannidis JP. Quantifying selective reporting and the Proteus phenomenon for multiple datasets with similar bias. PLoS One. 2011; 6(3):e18362.
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  113. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Hum Genet. 2011 Aug; 19(8):833-6.
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  114. Rizos EC, Salanti G, Kontoyiannis DP, Ioannidis JP. Homophily and co-occurrence patterns shape randomized trials agendas: illustration in antifungal agents. J Clin Epidemiol. 2011 Aug; 64(8):830-42.
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  115. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. J Clin Epidemiol. 2011 Aug; 64(8):e1-e22.
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  116. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. BMJ. 2011; 342:d631.
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  117. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement. J Clin Epidemiol. 2011 Aug; 64(8):843-7.
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  118. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies: The GRIPS Statement. Ann Intern Med. 2011 Mar 15; 154(6):421-5.
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  119. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement. PLoS Med. 2011 Mar; 8(3):e1000420.
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  120. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Circ Cardiovasc Genet. 2011 Apr; 4(2):206-9.
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  121. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Clin Invest. 2011 Sep; 41(9):1004-9.
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  122. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Genome Med. 2011; 3(3):16.
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  123. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Clin Invest. 2011 Sep; 41(9):1010-35.
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  124. Polyzos NP, Valachis A, Mauri D, Ioannidis JP. Industry involvement and baseline assumptions of cost-effectiveness analyses: diagnostic accuracy of the Papanicolaou test. CMAJ. 2011 Apr 5; 183(6):E337-43.
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  125. Elbaz A, Ross OA, Ioannidis JP, Soto-Ortolaza AI, Moisan F, Aasly J, Annesi G, Bozi M, Brighina L, Chartier-Harlin MC, Destée A, Ferrarese C, Ferraris A, Gibson JM, Gispert S, Hadjigeorgiou GM, Jasinska-Myga B, Klein C, Krüger R, Lambert JC, Lohmann K, van de Loo S, Loriot MA, Lynch T, Mellick GD, Mutez E, Nilsson C, Opala G, Puschmann A, Quattrone A, Sharma M, Silburn PA, Stefanis L, Uitti RJ, Valente EM, Vilariño-Güell C, Wirdefeldt K, Wszolek ZK, Xiromerisiou G, Maraganore DM, Farrer MJ. Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. Ann Neurol. 2011 May; 69(5):778-92.
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  126. Tzoulaki I, Liberopoulos G, Ioannidis JP. Use of reclassification for assessment of improved prediction: an empirical evaluation. Int J Epidemiol. 2011 Aug; 40(4):1094-105.
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  127. Castaldi PJ, Dahabreh IJ, Ioannidis JP. An empirical assessment of validation practices for molecular classifiers. Brief Bioinform. 2011 May; 12(3):189-202.
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  128. Panagiotou OA, Contopoulos-Ioannidis DG, Papanikolaou PN, Ntzani EE, Ioannidis JP. Different black box warning labeling for same-class drugs. J Gen Intern Med. 2011 Jun; 26(6):603-10.
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  129. Ioannidis JP. Commentary: Adjusting for bias: a user's guide to performing plastic surgery on meta-analyses of observational studies. Int J Epidemiol. 2011 Jun; 40(3):777-9.
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  130. Loizidou MA, Hadjisavvas A, Ioannidis JP, Kyriacou K. Replication of genome-wide discovered breast cancer risk loci in the Cypriot population. Breast Cancer Res Treat. 2011 Jul; 128(1):267-72.
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  131. Ntzani EE, Khoury MJ, Ioannidis JP. Combining molecular and genetic data from different sources. IARC Sci Publ. 2011; (163):323-36.
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  132. Panoutsopoulou K, Southam L, Elliott KS, Wrayner N, Zhai G, Beazley C, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Doherty M, McCaskie A, Ollier WE, Ralston SH, Spector TD, Valdes AM, Wallis GA, Wilkinson JM, Arden E, Battley K, Blackburn H, Blanco FJ, Bumpstead S, Cupples LA, Day-Williams AG, Dixon K, Doherty SA, Esko T, Evangelou E, Felson D, Gomez-Reino JJ, Gonzalez A, Gordon A, Gwilliam R, Halldorsson BV, Hauksson VB, Hofman A, Hunt SE, Ioannidis JP, Ingvarsson T, Jonsdottir I, Jonsson H, Keen R, Kerkhof HJ, Kloppenburg MG, Koller N, Lakenberg N, Lane NE, Lee AT, Metspalu A, Meulenbelt I, Nevitt MC, O'Neill F, Parimi N, Potter SC, Rego-Perez I, Riancho JA, Sherburn K, Slagboom PE, Stefansson K, Styrkarsdottir U, Sumillera M, Swift D, Thorsteinsdottir U, Tsezou A, Uitterlinden AG, van Meurs JB, Watkins B, Wheeler M, Mitchell S, Zhu Y, Zmuda JM, Zeggini E, Loughlin J. Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Ann Rheum Dis. 2011 May; 70(5):864-7.
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  133. van Assen S, Elkayam O, Agmon-Levin N, Cervera R, Doran MF, Dougados M, Emery P, Geborek P, Ioannidis JP, Jayne DR, Kallenberg CG, Müller-Ladner U, Shoenfeld Y, Stojanovich L, Valesini G, Wulffraat NM, Bijl M. Vaccination in adult patients with auto-immune inflammatory rheumatic diseases: a systematic literature review for the European League Against Rheumatism evidence-based recommendations for vaccination in adult patients with auto-immune inflammatory rheumatic diseases. Autoimmun Rev. 2011 Apr; 10(6):341-52.
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  134. Ioannidis JP, Siontis GC. Re: Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition. J Natl Cancer Inst. 2011 Feb 2; 103(3):279-80; author reply 280-1.
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  135. van Assen S, Agmon-Levin N, Elkayam O, Cervera R, Doran MF, Dougados M, Emery P, Geborek P, Ioannidis JP, Jayne DR, Kallenberg CG, Müller-Ladner U, Shoenfeld Y, Stojanovich L, Valesini G, Wulffraat NM, Bijl M. EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases. Ann Rheum Dis. 2011 Mar; 70(3):414-22.
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  136. Evangelou E, Valdes AM, Kerkhof HJ, Styrkarsdottir U, Zhu Y, Meulenbelt I, Lories RJ, Karassa FB, Tylzanowski P, Bos SD, Akune T, Arden NK, Carr A, Chapman K, Cupples LA, Dai J, Deloukas P, Doherty M, Doherty S, Engstrom G, Gonzalez A, Halldorsson BV, Hammond CL, Hart DJ, Helgadottir H, Hofman A, Ikegawa S, Ingvarsson T, Jiang Q, Jonsson H, Kaprio J, Kawaguchi H, Kisand K, Kloppenburg M, Kujala UM, Lohmander LS, Loughlin J, Luyten FP, Mabuchi A, McCaskie A, Nakajima M, Nilsson PM, Nishida N, Ollier WE, Panoutsopoulou K, van de Putte T, Ralston SH, Rivadeneira F, Saarela J, Schulte-Merker S, Shi D, Slagboom PE, Sudo A, Tamm A, Tamm A, Thorleifsson G, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Yoshimura N, Zeggini E, Zhai G, Zhang F, Jonsdottir I, Uitterlinden AG, Felson DT, van Meurs JB, Stefansson K, Ioannidis JP, Spector TD. Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis. 2011 Feb; 70(2):349-55.
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  137. Kitsios GD, Tangri N, Castaldi PJ, Ioannidis JP. Laboratory mouse models for the human genome-wide associations. PLoS One. 2010; 5(11):e13782.
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  138. Salanti G, Dias S, Welton NJ, Ades AE, Golfinopoulos V, Kyrgiou M, Mauri D, Ioannidis JP. Evaluating novel agent effects in multiple-treatments meta-regression. Stat Med. 2010 Oct 15; 29(23):2369-83.
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  139. Langevin SM, Ioannidis JP, Vineis P, Taioli E. Assessment of cumulative evidence for the association between glutathione S-transferase polymorphisms and lung cancer: application of the Venice interim guidelines. Pharmacogenet Genomics. 2010 Oct; 20(10):586-97.
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  140. Panagiotou OA, Evangelou E, Ioannidis JP. Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review. Am J Epidemiol. 2010 Oct 15; 172(8):869-89.
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  141. Valdes AM, Evangelou E, Kerkhof HJ, Tamm A, Doherty SA, Kisand K, Tamm A, Kerna I, Uitterlinden A, Hofman A, Rivadeneira F, Cooper C, Dennison EM, Zhang W, Muir KR, Ioannidis JP, Wheeler M, Maciewicz RA, van Meurs JB, Arden NK, Spector TD, Doherty M. The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance. Ann Rheum Dis. 2011 May; 70(5):873-5.
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  142. Ioannidis JP, Karassa FB. The need to consider the wider agenda in systematic reviews and meta-analyses: breadth, timing, and depth of the evidence. BMJ. 2010; 341:c4875.
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  143. Ioannidis JP, Belbasis L, Evangelou E. Fifty-year fate and impact of general medical journals. PLoS One. 2010; 5(9).
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  144. Ioannidis JP, Tatsioni A, Karassa FB. Published articles should not be dead and buried: introducing research updates. Eur J Clin Invest. 2010 Sep; 40(9):767-9.
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  145. Jin H, Evangelou E, Ioannidis JP, Ralston SH. Polymorphisms in the 5' flank of COL1A1 gene and osteoporosis: meta-analysis of published studies. Osteoporos Int. 2011 Mar; 22(3):911-21.
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  146. Mischak H, Allmaier G, Apweiler R, Attwood T, Baumann M, Benigni A, Bennett SE, Bischoff R, Bongcam-Rudloff E, Capasso G, Coon JJ, D'Haese P, Dominiczak AF, Dakna M, Dihazi H, Ehrich JH, Fernandez-Llama P, Fliser D, Frokiaer J, Garin J, Girolami M, Hancock WS, Haubitz M, Hochstrasser D, Holman RR, Ioannidis JP, Jankowski J, Julian BA, Klein JB, Kolch W, Luider T, Massy Z, Mattes WB, Molina F, Monsarrat B, Novak J, Peter K, Rossing P, Sánchez-Carbayo M, Schanstra JP, Semmes OJ, Spasovski G, Theodorescu D, Thongboonkerd V, Vanholder R, Veenstra TD, Weissinger E, Yamamoto T, Vlahou A. Recommendations for biomarker identification and qualification in clinical proteomics. Sci Transl Med. 2010 Aug 25; 2(46):46ps42.
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  147. Bertsias GK, Ioannidis JP, Aringer M, Bollen E, Bombardieri S, Bruce IN, Cervera R, Dalakas M, Doria A, Hanly JG, Huizinga TW, Isenberg D, Kallenberg C, Piette JC, Schneider M, Scolding N, Smolen J, Stara A, Tassiulas I, Tektonidou M, Tincani A, van Buchem MA, van Vollenhoven R, Ward M, Gordon C, Boumpas DT. EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs. Ann Rheum Dis. 2010 Dec; 69(12):2074-82.
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  148. Katritsis DG, Siontis GC, Kastrati A, van't Hof AW, Neumann FJ, Siontis KC, Ioannidis JP. Optimal timing of coronary angiography and potential intervention in non-ST-elevation acute coronary syndromes. Eur Heart J. 2011 Jan; 32(1):32-40.
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  149. Kent DM, Rothwell PM, Ioannidis JP, Altman DG, Hayward RA. Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal. Trials. 2010; 11:85.
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  150. Khoury MJ, Gwinn M, Ioannidis JP. The emergence of translational epidemiology: from scientific discovery to population health impact. Am J Epidemiol. 2010 Sep 1; 172(5):517-24.
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  151. Salanti G, Ades AE, Ioannidis JP. Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol. 2011 Feb; 64(2):163-71.
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  152. Ioannidis JP. Is there a glass ceiling for highly cited scientists at the top of research universities? FASEB J. 2010 Dec; 24(12):4635-8.
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  153. Contopoulos-Ioannidis DG, Baltogianni MS, Ioannidis JP. Comparative effectiveness of medical interventions in adults versus children. J Pediatr. 2010 Aug; 157(2):322-330.e17.
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  154. Ioannidis JP. Expectations, validity, and reality in omics. J Clin Epidemiol. 2010 Sep; 63(9):945-9.
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  155. Siontis GC, Patsopoulos NA, Vlahos AP, Ioannidis JP. Selection and presentation of imaging figures in the medical literature. PLoS One. 2010; 5(5):e10888.
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  156. Elliott KS, Zeggini E, McCarthy MI, Gudmundsson J, Sulem P, Stacey SN, Thorlacius S, Amundadottir L, Grönberg H, Xu J, Gaborieau V, Eeles RA, Neal DE, Donovan JL, Hamdy FC, Muir K, Hwang SJ, Spitz MR, Zanke B, Carvajal-Carmona L, Brown KM, Hayward NK, Macgregor S, Tomlinson IP, Lemire M, Amos CI, Murabito JM, Isaacs WB, Easton DF, Brennan P, Barkardottir RB, Gudbjartsson DF, Rafnar T, Hunter DJ, Chanock SJ, Stefansson K, Ioannidis JP. Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies. PLoS One. 2010; 5(5):e10858.
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  157. Ioannidis JP, Castaldi P, Evangelou E. A compendium of genome-wide associations for cancer: critical synopsis and reappraisal. J Natl Cancer Inst. 2010 Jun 16; 102(12):846-58.
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  158. Dolan SM, Hollegaard MV, Merialdi M, Betran AP, Allen T, Abelow C, Nace J, Lin BK, Khoury MJ, Ioannidis JP, Bagade S, Zheng X, Dubin RA, Bertram L, Velez Edwards DR, Menon R. Synopsis of preterm birth genetic association studies: the preterm birth genetics knowledge base (PTBGene). Public Health Genomics. 2010; 13(7-8):514-23.
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  159. Ioannidis JP, Tzoulaki I. What makes a good predictor?: the evidence applied to coronary artery calcium score. JAMA. 2010 Apr 28; 303(16):1646-7.
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  160. Tatsioni A, Siontis GC, Ioannidis JP. Partisan perspectives in the medical literature: a study of high frequency editorialists favoring hormone replacement therapy. J Gen Intern Med. 2010 Sep; 25(9):914-9.
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  161. Chavalarias D, Ioannidis JP. Science mapping analysis characterizes 235 biases in biomedical research. J Clin Epidemiol. 2010 Nov; 63(11):1205-15.
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  162. Stergiou GS, Siontis KC, Ioannidis JP. Home blood pressure as a cardiovascular outcome predictor: it's time to take this method seriously. Hypertension. 2010 Jun; 55(6):1301-3.
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  163. Dimoliatis ID, Vasilaki E, Anastassopoulos P, Ioannidis JP, Roff S. Validation of the Greek translation of the Dundee Ready Education Environment Measure (DREEM). Educ Health (Abingdon). 2010 Apr; 23(1):348.
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  164. Ioannidis JP, Tatsioni A, Karassa FB. Who is afraid of reviewers' comments? Or, why anything can be published and anything can be cited. Eur J Clin Invest. 2010 Apr; 40(4):285-7.
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  165. Lill CM, Schjeide BM, Roehr JT, Zauft U, Allen NC, Zipp F, McQueen MB, Kavvoura FK, Ioannidis JP, Khoury MJ, Tanzi RE, Bertram L. Correspondence to Sand et Al. "Critical reappraisal of a catechol-o-methyltransferase transversion variant in schizophrenia". Biol Psychiatry. 2010 Apr 1; 67(7):e45-8.
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  166. Kitsos G, Petrou Z, Grigoriadou M, Samples JR, Hewitt AW, Kokotas H, Giannoulia-Karantana A, Mackey DA, Wirtz MK, Moschou M, Ioannidis JP, Petersen MB. Primary open angle glaucoma due to T377M MYOC: Population mapping of a Greek founder mutation in Northwestern Greece. Clin Ophthalmol. 2010; 4:171-8.
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  167. Siontis KC, Patsopoulos NA, Ioannidis JP. Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies. Eur J Hum Genet. 2010 Jul; 18(7):832-7.
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  168. Kerkhof HJ, Lories RJ, Meulenbelt I, Jonsdottir I, Valdes AM, Arp P, Ingvarsson T, Jhamai M, Jonsson H, Stolk L, Thorleifsson G, Zhai G, Zhang F, Zhu Y, van der Breggen R, Carr A, Doherty M, Doherty S, Felson DT, Gonzalez A, Halldorsson BV, Hart DJ, Hauksson VB, Hofman A, Ioannidis JP, Kloppenburg M, Lane NE, Loughlin J, Luyten FP, Nevitt MC, Parimi N, Pols HA, Rivadeneira F, Slagboom EP, Styrkársdóttir U, Tsezou A, van de Putte T, Zmuda J, Spector TD, Stefansson K, Uitterlinden AG, van Meurs JB. A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum. 2010 Feb; 62(2):499-510.
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  169. Galvan A, Ioannidis JP, Dragani TA. Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer. Trends Genet. 2010 Mar; 26(3):132-41.
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  170. Tatsioni A, Vavva E, Ioannidis JP. Sources of funding for Nobel Prize-winning work: public or private? FASEB J. 2010 May; 24(5):1335-9.
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  171. Evangelou E, Maraganore DM, Annesi G, Brighina L, Brice A, Elbaz A, Ferrarese C, Hadjigeorgiou GM, Krueger R, Lambert JC, Lesage S, Markopoulou K, Mellick GD, Meeus B, Pedersen NL, Quattrone A, Van Broeckhoven C, Sharma M, Silburn PA, Tan EK, Wirdefeldt K, Ioannidis JP. Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5; 153B(1):220-8.
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  172. Ioannidis JP, Tatsioni A, Karassa FB. A vision for the European journal of clinical investigation: note from the new editors. Eur J Clin Invest. 2010 Jan; 40(1):1-3.
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  173. Tsianos GI, Evangelou E, Boot A, Zillikens MC, van Meurs JB, Uitterlinden AG, Ioannidis JP. Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners. J Appl Physiol. 2010 Mar; 108(3):567-74.
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  174. Lathyris DN, Patsopoulos NA, Salanti G, Ioannidis JP. Industry sponsorship and selection of comparators in randomized clinical trials. Eur J Clin Invest. 2010 Feb; 40(2):172-82.
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  175. Krüger R, Sharma M, Riess O, Gasser T, Van Broeckhoven C, Theuns J, Aasly J, Annesi G, Bentivoglio AR, Brice A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Klein C, Lambert JC, Lesage S, Lin JJ, Lynch T, Mellick GD, de Nigris F, Opala G, Prigione A, Quattrone A, Ross OA, Satake W, Silburn PA, Tan EK, Toda T, Tomiyama H, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM. A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease. Neurobiol Aging. 2011 Mar; 32(3):548.e9-18.
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  176. Tzoulaki I, Liberopoulos G, Ioannidis JP. Assessment of claims of improved prediction beyond the Framingham risk score. JAMA. 2009 Dec 2; 302(21):2345-52.
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  177. Yang Q, Flanders WD, Moonesinghe R, Ioannidis JP, Guessous I, Khoury MJ. Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty. Am J Hum Genet. 2009 Dec; 85(6):786-800.
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  178. Ioannidis JP, Loy EY, Poulton R, Chia KS. Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification. Sci Transl Med. 2009 Nov 18; 1(7):7ps8.
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  179. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. STrengthening the REporting of Genetic Association Studies (STREGA)--an extension of the STROBE statement. Genet Epidemiol. 2009 Nov; 33(7):581-98.
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  180. Ioannidis JP. Adverse events in randomized trials: neglected, restricted, distorted, and silenced. Arch Intern Med. 2009 Oct 26; 169(19):1737-9.
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  181. Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu YH, Zillikens MC, Wilson SG, Mullin BH, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra BA, Pols HA, Sigurdsson G, Thorsteinsdottir U, Soranzo N, Williams FM, Zhou Y, Ralston SH, Thorleifsson G, van Duijn CM, Kiel DP, Stefansson K, Uitterlinden AG, Ioannidis JP, Spector TD. Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med. 2009 Oct 20; 151(8):528-37.
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  182. Sotiriadis A, Makrydimas G, Papatheodorou S, Ioannidis JP. Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. Cochrane Database Syst Rev. 2009; (4):CD006614.
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  183. Pereira TV, Patsopoulos NA, Salanti G, Ioannidis JP. Discovery properties of genome-wide association signals from cumulatively combined data sets. Am J Epidemiol. 2009 Nov 15; 170(10):1197-206.
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  184. Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra B, Pastinen T, Pols HA, Sigurdsson G, Soranzo N, Thorleifsson G, Thorsteinsdottir U, Williams FM, Wilson SG, Zhou Y, Ralston SH, van Duijn CM, Spector T, Kiel DP, Stefansson K, Ioannidis JP, Uitterlinden AG. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet. 2009 Nov; 41(11):1199-206.
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  185. Katritsis DG, Siontis GC, Ioannidis JP. Double versus single stenting for coronary bifurcation lesions: a meta-analysis. Circ Cardiovasc Interv. 2009 Oct; 2(5):409-15.
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  186. Ioannidis JP. Population-wide generalizability of genome-wide discovered associations. J Natl Cancer Inst. 2009 Oct 7; 101(19):1297-9.
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  187. Ioannidis JP. Integration of evidence from multiple meta-analyses: a primer on umbrella reviews, treatment networks and multiple treatments meta-analyses. CMAJ. 2009 Oct 13; 181(8):488-93.
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  188. Manzoli L, Salanti G, De Vito C, Boccia A, Ioannidis JP, Villari P. Immunogenicity and adverse events of avian influenza A H5N1 vaccine in healthy adults: multiple-treatments meta-analysis. Lancet Infect Dis. 2009 Aug; 9(8):482-92.
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  189. Khoury MJ, McBride CM, Schully SD, Ioannidis JP, Feero WG, Janssens AC, Gwinn M, Simons-Morton DG, Bernhardt JM, Cargill M, Chanock SJ, Church GM, Coates RJ, Collins FS, Croyle RT, Davis BR, Downing GJ, Duross A, Friedman S, Gail MH, Ginsburg GS, Green RC, Greene MH, Greenland P, Gulcher JR, Hsu A, Hudson KL, Kardia SL, Kimmel PL, Lauer MS, Miller AM, Offit K, Ransohoff DF, Roberts JS, Rasooly RS, Stefansson K, Terry SF, Teutsch SM, Trepanier A, Wanke KL, Witte JS, Xu J. The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med. 2009 Aug; 11(8):559-67.
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  190. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol. 2009 Oct; 62(10):e1-34.
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  191. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009 Jul 21; 6(7):e1000100.
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  192. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009; 339:b2700.
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  193. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med. 2009 Aug 18; 151(4):W65-94.
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  194. Salanti G, Southam L, Altshuler D, Ardlie K, Barroso I, Boehnke M, Cornelis MC, Frayling TM, Grallert H, Grarup N, Groop L, Hansen T, Hattersley AT, Hu FB, Hveem K, Illig T, Kuusisto J, Laakso M, Langenberg C, Lyssenko V, McCarthy MI, Morris A, Morris AD, Palmer CN, Payne F, Platou CG, Scott LJ, Voight BF, Wareham NJ, Zeggini E, Ioannidis JP. Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol. 2009 Sep 1; 170(5):537-45.
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  195. Golfinopoulos V, Pentheroudakis G, Salanti G, Nearchou AD, Ioannidis JP, Pavlidis N. Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: multiple-treatments meta-analysis. Cancer Treat Rev. 2009 Nov; 35(7):570-3.
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  196. Khoury MJ, Bertram L, Boffetta P, Butterworth AS, Chanock SJ, Dolan SM, Fortier I, Garcia-Closas M, Gwinn M, Higgins JP, Janssens AC, Ostell J, Owen RP, Pagon RA, Rebbeck TR, Rothman N, Bernstein JL, Burton PR, Campbell H, Chockalingam A, Furberg H, Little J, O'Brien TR, Seminara D, Vineis P, Winn DM, Yu W, Ioannidis JP. Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol. 2009 Aug 1; 170(3):269-79.
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  197. Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gómez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A, Hart DJ, Ikegawa S, Ingvarsson T, Jiang Q, Jonsdottir I, Jonsson H, Kerkhof HJ, Kloppenburg M, Lane NE, Li J, Lories RJ, van Meurs JB, Näkki A, Nevitt MC, Rodriguez-Lopez J, Shi D, Slagboom PE, Stefansson K, Tsezou A, Wallis GA, Watson CM, Spector TD, Uitterlinden AG, Valdes AM, Ioannidis JP. Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum. 2009 Jun; 60(6):1710-21.
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  198. Patsopoulos NA, Ioannidis JP. The use of older studies in meta-analyses of medical interventions: a survey. Open Med. 2009; 3(2):e62-8.
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  199. Ioannidis JP. Ranking antidepressants. Lancet. 2009 May 23; 373(9677):1759-60; author reply 1761-2.
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  200. Ioannidis JP, Thomas G, Daly MJ. Validating, augmenting and refining genome-wide association signals. Nat Rev Genet. 2009 May; 10(5):318-29.
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  201. Patsopoulos NA, Ioannidis JP. Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis. Ann Rheum Dis. 2010 Mar; 69(3):561-6.
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  202. Liberopoulos G, Trikalinos NA, Ioannidis JP. The elderly were under-represented in osteoarthritis clinical trials. J Clin Epidemiol. 2009 Nov; 62(11):1218-23.
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  203. Pakos EE, Nearchou AD, Grimer RJ, Koumoullis HD, Abudu A, Bramer JA, Jeys LM, Franchi A, Scoccianti G, Campanacci D, Capanna R, Aparicio J, Tabone MD, Holzer G, Abdolvahab F, Funovics P, Dominkus M, Ilhan I, Berrak SG, Patino-Garcia A, Sierrasesumaga L, San-Julian M, Garraus M, Petrilli AS, Filho RJ, Macedo CR, Alves MT, Seiwerth S, Nagarajan R, Cripe TP, Ioannidis JP. Prognostic factors and outcomes for osteosarcoma: an international collaboration. Eur J Cancer. 2009 Sep; 45(13):2367-75.
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  204. Siontis GC, Tatsioni A, Katritsis DG, Ioannidis JP. Persistent reservations against contradicted percutaneous coronary intervention indications: citation content analysis. Am Heart J. 2009 Apr; 157(4):695-701.
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  205. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement. Eur J Clin Invest. 2009 Apr; 39(4):247-66.
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  206. Janssens AC, González-Zuloeta Ladd AM, López-Léon S, Ioannidis JP, Oostra BA, Khoury MJ, van Duijn CM. An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses. Genet Med. 2009 Mar; 11(3):153-62.
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  207. Lumbreras B, Parker LA, Porta M, Pollán M, Ioannidis JP, Hernández-Aguado I. Overinterpretation of clinical applicability in molecular diagnostic research. Clin Chem. 2009 Apr; 55(4):786-94.
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  208. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart AF, Birkett N. Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. J Clin Epidemiol. 2009 Jun; 62(6):597-608.e4.
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  209. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. PLoS Med. 2009 Feb 3; 6(2):e22.
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  210. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement. Ann Intern Med. 2009 Feb 3; 150(3):206-15.
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  211. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement. Eur J Epidemiol. 2009; 24(1):37-55.
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  212. Zeggini E, Ioannidis JP. Meta-analysis in genome-wide association studies. Pharmacogenomics. 2009 Feb; 10(2):191-201.
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  213. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, van Duijn C, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement. Hum Genet. 2009 Mar; 125(2):131-51.
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  214. Salanti G, Ioannidis JP. Synthesis of observational studies should consider credibility ceilings. J Clin Epidemiol. 2009 Feb; 62(2):115-22.
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  215. Ioannidis JP. Prediction of cardiovascular disease outcomes and established cardiovascular risk factors by genome-wide association markers. Circ Cardiovasc Genet. 2009 Feb; 2(1):7-15.
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  216. Attia J, Ioannidis JP, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. How to use an article about genetic association: C: What are the results and will they help me in caring for my patients? JAMA. 2009 Jan 21; 301(3):304-8.
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  217. Ioannidis JP. Personalized genetic prediction: too limited, too expensive, or too soon? Ann Intern Med. 2009 Jan 20; 150(2):139-41.
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  218. Attia J, Ioannidis JP, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. How to use an article about genetic association: B: Are the results of the study valid? JAMA. 2009 Jan 14; 301(2):191-7.
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  219. Contopoulos-Ioannidis DG, Karvouni A, Kouri I, Ioannidis JP. Reporting and interpretation of SF-36 outcomes in randomised trials: systematic review. BMJ. 2009; 338:a3006.
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  220. Attia J, Ioannidis JP, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. How to use an article about genetic association: A: Background concepts. JAMA. 2009 Jan 7; 301(1):74-81.
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  221. Vineis P, Manuguerra M, Kavvoura FK, Guarrera S, Allione A, Rosa F, Di Gregorio A, Polidoro S, Saletta F, Ioannidis JP, Matullo G. A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. J Natl Cancer Inst. 2009 Jan 7; 101(1):24-36.
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  222. Mauri D, Polyzos NP, Salanti G, Pavlidis N, Ioannidis JP. Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer. J Natl Cancer Inst. 2008 Dec 17; 100(24):1780-91.
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  223. Patsopoulos NA, Evangelou E, Ioannidis JP. Heterogeneous views on heterogeneity. Int J Epidemiol. 2009 Dec; 38(6):1740-2.
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  224. Young NS, Ioannidis JP, Al-Ubaydli O. Why current publication practices may distort science. PLoS Med. 2008 Oct 7; 5(10):e201.
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  225. Stefanis NC, Trikalinos TA, Avramopoulos D, Smyrnis N, Evdokimidis I, Ntzani EE, Hatzimanolis A, Ioannidis JP, Stefanis CN. Association of RGS4 variants with schizotypy and cognitive endophenotypes at the population level. Behav Brain Funct. 2008; 4:46.
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  226. Ioannidis JP. Interpretation of tests of heterogeneity and bias in meta-analysis. J Eval Clin Pract. 2008 Oct; 14(5):951-7.
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  227. Thorlund K, Devereaux PJ, Wetterslev J, Guyatt G, Ioannidis JP, Thabane L, Gluud LL, Als-Nielsen B, Gluud C. Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? Int J Epidemiol. 2009 Feb; 38(1):276-86.
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  228. Kavvoura FK, McQueen MB, Khoury MJ, Tanzi RE, Bertram L, Ioannidis JP. Evaluation of the potential excess of statistically significant findings in published genetic association studies: application to Alzheimer's disease. Am J Epidemiol. 2008 Oct 15; 168(8):855-65.
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  229. Contopoulos-Ioannidis DG, Alexiou GA, Gouvias TC, Ioannidis JP. Medicine. Life cycle of translational research for medical interventions. Science. 2008 Sep 5; 321(5894):1298-9.
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  230. Ioannidis JP. Calibration of credibility of agnostic genome-wide associations. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5; 147B(6):964-72.
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  231. Vineis P, Brennan P, Canzian F, Ioannidis JP, Matullo G, Ritchie M, Stromberg U, Taioli E, Thompson J. Expectations and challenges stemming from genome-wide association studies. Mutagenesis. 2008 Nov; 23(6):439-44.
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  232. Karassa FB, Ioannidis JP. Mortality in systemic sclerosis. Clin Exp Rheumatol. 2008 Sep-Oct; 26(5 Suppl 51):S85-93.
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  233. Ioannidis JP. Why most discovered true associations are inflated. Epidemiology. 2008 Sep; 19(5):640-8.
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  234. Dwan K, Altman DG, Arnaiz JA, Bloom J, Chan AW, Cronin E, Decullier E, Easterbrook PJ, Von Elm E, Gamble C, Ghersi D, Ioannidis JP, Simes J, Williamson PR. Systematic review of the empirical evidence of study publication bias and outcome reporting bias. PLoS One. 2008; 3(8):e3081.
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  235. Ioannidis JP. Measuring co-authorship and networking-adjusted scientific impact. PLoS One. 2008; 3(7):e2778.
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  236. Simitsopoulou M, Roilides E, Paliogianni F, Likartsis C, Ioannidis J, Kanellou K, Walsh TJ. Immunomodulatory effects of voriconazole on monocytes challenged with Aspergillus fumigatus: differential role of Toll-like receptors. Antimicrob Agents Chemother. 2008 Sep; 52(9):3301-6.
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  237. Ioannidis JP. Effect of formal statistical significance on the credibility of observational associations. Am J Epidemiol. 2008 Aug 15; 168(4):374-83; discussion 384-90.
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  238. Ioannidis JP. Interpretation of research results: an indispensable mission impossible? Semin Hematol. 2008 Jul; 45(3):133-4.
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  239. Ioannidis JP. Perfect study, poor evidence: interpretation of biases preceding study design. Semin Hematol. 2008 Jul; 45(3):160-6.
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  240. Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet. 2008 Jul; 40(7):827-34.
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  241. Ioannidis JP, Patsopoulos NA, Rothstein HR. Reasons or excuses for avoiding meta-analysis in forest plots. BMJ. 2008 Jun 21; 336(7658):1413-5.
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  242. Ioannidis JP. Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials? Philos Ethics Humanit Med. 2008; 3:14.
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  243. Evangelou E, Tsianos G, Ioannidis JP. Doctors' versus patients' global assessments of treatment effectiveness: empirical survey of diverse treatments in clinical trials. BMJ. 2008 Jun 7; 336(7656):1287-90.
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  244. Yesupriya A, Evangelou E, Kavvoura FK, Patsopoulos NA, Clyne M, Walsh MC, Lin BK, Yu W, Gwinn M, Ioannidis JP, Khoury MJ. Reporting of human genome epidemiology (HuGE) association studies: an empirical assessment. BMC Med Res Methodol. 2008; 8:31.
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  245. Kyzas PA, Evangelou E, Denaxa-Kyza D, Ioannidis JP. 18F-fluorodeoxyglucose positron emission tomography to evaluate cervical node metastases in patients with head and neck squamous cell carcinoma: a meta-analysis. J Natl Cancer Inst. 2008 May 21; 100(10):712-20.
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  246. Hernandez AV, Walker E, Ioannidis JP, Kattan MW. Challenges in meta-analysis of randomized clinical trials for rare harmful cardiovascular events: the case of rosiglitazone. Am Heart J. 2008 Jul; 156(1):23-30.
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  247. McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, Hirschhorn JN. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet. 2008 May; 9(5):356-69.
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  248. Trikalinos NA, Evangelou E, Ioannidis JP. Falsified papers in high-impact journals were slow to retract and indistinguishable from nonfraudulent papers. J Clin Epidemiol. 2008 May; 61(5):464-70.
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  249. Bertsias GK, Ioannidis JP, Boletis J, Bombardieri S, Cervera R, Dostal C, Font J, Gilboe IM, Houssiau F, Huizinga T, Isenberg D, Kallenberg CG, Khamashta M, Piette JC, Schneider M, Smolen J, Sturfelt G, Tincani A, van Vollenhoven R, Boumpas DT, Gordon C. EULAR points to consider for conducting clinical trials in systemic lupus erythematosus: literature based evidence for the selection of endpoints. Ann Rheum Dis. 2009 Apr; 68(4):477-83.
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  250. Patsopoulos NA, Evangelou E, Ioannidis JP. Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol. 2008 Oct; 37(5):1148-57.
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  251. Gordon C, Bertsias G, Ioannidis JP, Boletis J, Bombardieri S, Cervera R, Dostál C, Font J, Gilboe IM, Houssiau F, Huizinga TW, Isenberg D, Kallenberg CG, Khamashta MA, Piette JC, Schneider M, Smolen JS, Sturfelt G, Tincani A, Van Vollenhoven R, Boumpas DT. EULAR points to consider for conducting clinical trials in systemic lupus erythematosus. Ann Rheum Dis. 2009 Apr; 68(4):470-6.
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  252. Salanti G, Kavvoura FK, Ioannidis JP. Exploring the geometry of treatment networks. Ann Intern Med. 2008 Apr 1; 148(7):544-53.
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  253. van Meurs JB, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Van Hul W, Agueda L, Akesson K, Benevolenskaya LI, Ferrari SL, Hallmans G, Hofman A, Husted LB, Kruk M, Kaptoge S, Karasik D, Karlsson MK, Lorentzon M, Masi L, McGuigan FE, Mellström D, Mosekilde L, Nogues X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Weber K, Ioannidis JP, Uitterlinden AG. Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA. 2008 Mar 19; 299(11):1277-90.
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  254. Papatheodorou SI, Trikalinos TA, Ioannidis JP. Inflated numbers of authors over time have not been just due to increasing research complexity. J Clin Epidemiol. 2008 Jun; 61(6):546-51.
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  255. Ioannidis JP, Allison DB, Ball CA, Coulibaly I, Cui X, Culhane AC, Falchi M, Furlanello C, Game L, Jurman G, Mangion J, Mehta T, Nitzberg M, Page GP, Petretto E, van Noort V. Repeatability of published microarray gene expression analyses. Nat Genet. 2009 Feb; 41(2):149-55.
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  256. Moonesinghe R, Khoury MJ, Liu T, Ioannidis JP. Required sample size and nonreplicability thresholds for heterogeneous genetic associations. Proc Natl Acad Sci U S A. 2008 Jan 15; 105(2):617-22.
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  257. Ioannidis JP. Some main problems eroding the credibility and relevance of randomized trials. Bull NYU Hosp Jt Dis. 2008; 66(2):135-9.
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  258. Trikalinos TA, Salanti G, Zintzaras E, Ioannidis JP. Meta-analysis methods. Adv Genet. 2008; 60:311-34.
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  259. Ioannidis JP, Adami HO. Nested randomized trials in large cohorts and biobanks: studying the health effects of lifestyle factors. Epidemiology. 2008 Jan; 19(1):75-82.
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  260. Tatsioni A, Bonitsis NG, Ioannidis JP. Persistence of contradicted claims in the literature. JAMA. 2007 Dec 5; 298(21):2517-26.
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  261. Langdahl BL, Uitterlinden AG, Ralston SH, Trikalinos TA, Balcells S, Brandi ML, Scollen S, Lips P, Lorenc R, Obermayer-Pietsch B, Reid DM, Armas JB, Arp PP, Bassiti A, Bustamante M, Husted LB, Carey AH, Pérez Cano R, Dobnig H, Dunning AM, Fahrleitner-Pammer A, Falchetti A, Karczmarewicz E, Kruk M, van Leeuwen JP, Masi L, van Meurs JB, Mangion J, McGuigan FE, Mellibovsky L, Mosekilde L, Nogués X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Ioannidis JP. Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study. Bone. 2008 May; 42(5):969-81.
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  262. Kavvoura FK, Ioannidis JP. Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls. Hum Genet. 2008 Feb; 123(1):1-14.
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  263. Kyzas PA, Denaxa-Kyza D, Ioannidis JP. Almost all articles on cancer prognostic markers report statistically significant results. Eur J Cancer. 2007 Nov; 43(17):2559-79.
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  264. Ioannidis JP, Patsopoulos NA, Evangelou E. Uncertainty in heterogeneity estimates in meta-analyses. BMJ. 2007 Nov 3; 335(7626):914-6.
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  265. Ioannidis JP, Patsopoulos NA, Kavvoura FK, Tatsioni A, Evangelou E, Kouri I, Contopoulos-Ioannidis DG, Liberopoulos G. International ranking systems for universities and institutions: a critical appraisal. BMC Med. 2007; 5:30.
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  266. Salanti G, Higgins JP, Ades AE, Ioannidis JP. Evaluation of networks of randomized trials. Stat Methods Med Res. 2008 Jun; 17(3):279-301.
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  267. Pakos EE, Koumoulis HD, Fotopoulos AD, Ioannidis JP. Osteomyelitis: antigranulocyte scintigraphy with 99mTC radiolabeled monoclonal antibodies for diagnosis-- meta-analysis. Radiology. 2007 Dec; 245(3):732-41.
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  268. Ioannidis JP, Boffetta P, Little J, O'Brien TR, Uitterlinden AG, Vineis P, Balding DJ, Chokkalingam A, Dolan SM, Flanders WD, Higgins JP, McCarthy MI, McDermott DH, Page GP, Rebbeck TR, Seminara D, Khoury MJ. Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol. 2008 Feb; 37(1):120-32.
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  269. Golfinopoulos V, Salanti G, Pavlidis N, Ioannidis JP. Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis. Lancet Oncol. 2007 Oct; 8(10):898-911.
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  270. Ioannidis JP, Katritsis DG. Percutaneous coronary intervention for late reperfusion after myocardial infarction in stable patients. Am Heart J. 2007 Dec; 154(6):1065-71.
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  271. Zintzaras E, Ioannidis JP. Meta-analysis for ranked discovery datasets: theoretical framework and empirical demonstration for microarrays. Comput Biol Chem. 2008 Feb; 32(1):38-46.
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  272. Higgins JP, Little J, Ioannidis JP, Bray MS, Manolio TA, Smeeth L, Sterne JA, Anagnostelis B, Butterworth AS, Danesh J, Dezateux C, Gallacher JE, Gwinn M, Lewis SJ, Minelli C, Pharoah PD, Salanti G, Sanderson S, Smith LA, Taioli E, Thompson JR, Thompson SG, Walker N, Zimmern RL, Khoury MJ. Turning the pump handle: evolving methods for integrating the evidence on gene-disease association. Am J Epidemiol. 2007 Oct 15; 166(8):863-6.
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  273. Ioannidis JP, Patsopoulos NA, Evangelou E. Heterogeneity in meta-analyses of genome-wide association investigations. PLoS One. 2007; 2(9):e841.
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  274. Ioannidis JP. Genetic and molecular epidemiology. J Epidemiol Community Health. 2007 Sep; 61(9):757-8.
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  275. Patsopoulos NA, Tatsioni A, Ioannidis JP. Claims of sex differences: an empirical assessment in genetic associations. JAMA. 2007 Aug 22; 298(8):880-93.
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  276. Contopoulos-Ioannidis DG, Kouri I, Ioannidis JP. Pharmacogenetics of the response to beta 2 agonist drugs: a systematic overview of the field. Pharmacogenomics. 2007 Aug; 8(8):933-58.
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  277. Katritsis DG, Ioannidis JP. PCI for stable coronary disease. N Engl J Med. 2007 Jul 26; 357(4):414-5; author reply 417-8.
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  278. Ioannidis JP, Polyzos NP, Trikalinos TA. Selective discussion and transparency in microarray research findings for cancer outcomes. Eur J Cancer. 2007 Sep; 43(13):1999-2010.
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  279. Ioannidis JP. Non-replication and inconsistency in the genome-wide association setting. Hum Hered. 2007; 64(4):203-13.
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  280. Khoury MJ, Little J, Higgins J, Ioannidis JP, Gwinn M. Reporting of systematic reviews: the challenge of genetic association studies. PLoS Med. 2007 Jun; 4(6):e211.
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  281. Ioannidis JP. Why most published research findings are false: author's reply to Goodman and Greenland. PLoS Med. 2007 Jun; 4(6):e215.
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  282. Bertsias G, Ioannidis JP, Boletis J, Bombardieri S, Cervera R, Dostal C, Font J, Gilboe IM, Houssiau F, Huizinga T, Isenberg D, Kallenberg CG, Khamashta M, Piette JC, Schneider M, Smolen J, Sturfelt G, Tincani A, van Vollenhoven R, Gordon C, Boumpas DT. EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics. Ann Rheum Dis. 2008 Feb; 67(2):195-205.
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  283. Kavvoura FK, Akamizu T, Awata T, Ban Y, Chistiakov DA, Frydecka I, Ghaderi A, Gough SC, Hiromatsu Y, Ploski R, Wang PW, Ban Y, Bednarczuk T, Chistiakova EI, Chojm M, Heward JM, Hiratani H, Juo SH, Karabon L, Katayama S, Kurihara S, Liu RT, Miyake I, Omrani GH, Pawlak E, Taniyama M, Tozaki T, Ioannidis JP. Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. J Clin Endocrinol Metab. 2007 Aug; 92(8):3162-70.
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  284. Ioannidis JP. Molecular evidence-based medicine: evolution and integration of information in the genomic era. Eur J Clin Invest. 2007 May; 37(5):340-9.
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  285. Ioannidis JP, Trikalinos TA. The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey. CMAJ. 2007 Apr 10; 176(8):1091-6.
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  286. Stefanis NC, Trikalinos TA, Avramopoulos D, Smyrnis N, Evdokimidis I, Ntzani EE, Ioannidis JP, Stefanis CN. Impact of schizophrenia candidate genes on schizotypy and cognitive endophenotypes at the population level. Biol Psychiatry. 2007 Oct 1; 62(7):784-92.
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  287. Kavvoura FK, Liberopoulos G, Ioannidis JP. Selection in reported epidemiological risks: an empirical assessment. PLoS Med. 2007 Mar; 4(3):e79.
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  288. Ioannidis JP. Is molecular profiling ready for use in clinical decision making? Oncologist. 2007 Mar; 12(3):301-11.
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  289. Lathyris DN, Trikalinos TA, Ioannidis JP. Evidence from crossover trials: empirical evaluation and comparison against parallel arm trials. Int J Epidemiol. 2007 Apr; 36(2):422-30.
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  290. Ntzani EE, Rizos EC, Ioannidis JP. Genetic effects versus bias for candidate polymorphisms in myocardial infarction: case study and overview of large-scale evidence. Am J Epidemiol. 2007 May 1; 165(9):973-84.
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  291. Salanti G, Higgins JP, Trikalinos TA, Ioannidis JP. Bayesian meta-analysis and meta-regression for gene-disease associations and deviations from Hardy-Weinberg equilibrium. Stat Med. 2007 Feb 10; 26(3):553-67.
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  292. Evangelou E, Maraganore DM, Ioannidis JP. Meta-analysis in genome-wide association datasets: strategies and application in Parkinson disease. PLoS One. 2007; 2(2):e196.
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  293. Kyzas PA, Denaxa-Kyza D, Ioannidis JP. Quality of reporting of cancer prognostic marker studies: association with reported prognostic effect. J Natl Cancer Inst. 2007 Feb 7; 99(3):236-43.
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  294. Ioannidis JP, Ng MY, Sham PC, Zintzaras E, Lewis CM, Deng HW, Econs MJ, Karasik D, Devoto M, Kammerer CM, Spector T, Andrew T, Cupples LA, Duncan EL, Foroud T, Kiel DP, Koller D, Langdahl B, Mitchell BD, Peacock M, Recker R, Shen H, Sol-Church K, Spotila LD, Uitterlinden AG, Wilson SG, Kung AW, Ralston SH. Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass. J Bone Miner Res. 2007 Feb; 22(2):173-83.
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  295. Ioannidis JP, Ahmed T, Awasthi S, Clarfield AM, Clark J, Dandona L, Howe A, Lozano JM, Li Y, Madani H, Marusic A, Mohammed I, Purcell GP, Rhoads M, Sliwa-Hähnle K, Straus SE, Edejer TT, Tugwell P, Ward R, Wilkes MS, Smith R. Open letter to the leader of academic medicine. BMJ. 2007 Jan 27; 334(7586):191-3.
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  296. Ioannidis JP. Limitations are not properly acknowledged in the scientific literature. J Clin Epidemiol. 2007 Apr; 60(4):324-9.
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  297. Ioannidis JP, Trikalinos TA. An exploratory test for an excess of significant findings. Clin Trials. 2007; 4(3):245-53.
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  298. Contopoulos-Ioannidis DG, Kouri IN, Ioannidis JP. Genetic predisposition to asthma and atopy. Respiration. 2007; 74(1):8-12.
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  299. Seminara D, Khoury MJ, O'Brien TR, Manolio T, Gwinn ML, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam AP, Danesh J, Davey Smith G, Dolan S, Duncan R, Gruis NA, Hashibe M, Hunter D, Jarvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, Riboli E, Salanti G, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham N, Winn DM, Zimmern R, Ioannidis JP. The emergence of networks in human genome epidemiology: challenges and opportunities. Epidemiology. 2007 Jan; 18(1):1-8.
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  300. Khoury MJ, Little J, Gwinn M, Ioannidis JP. On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies. Int J Epidemiol. 2007 Apr; 36(2):439-45.
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  301. Christou MA, Siontis GC, Katritsis DG, Ioannidis JP. Meta-analysis of fractional flow reserve versus quantitative coronary angiography and noninvasive imaging for evaluation of myocardial ischemia. Am J Cardiol. 2007 Feb 15; 99(4):450-6.
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  302. Ioannidis JP. Concentration of the most-cited papers in the scientific literature: analysis of journal ecosystems. PLoS One. 2006; 1:e5.
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  303. Simitsopoulou M, Roilides E, Likartsis C, Ioannidis J, Orfanou A, Paliogianni F, Walsh TJ. Expression of immunomodulatory genes in human monocytes induced by voriconazole in the presence of Aspergillus fumigatus. Antimicrob Agents Chemother. 2007 Mar; 51(3):1048-54.
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  304. Ioannidis JP. Evolution and translation of research findings: from bench to where? PLoS Clin Trials. 2006; 1(7):e36.
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  305. Tzioras S, Pavlidis N, Paraskevaidis E, Ioannidis JP. Effects of different chemotherapy regimens on survival for advanced cervical cancer: systematic review and meta-analysis. Cancer Treat Rev. 2007 Feb; 33(1):24-38.
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  306. Kyrgiou M, Salanti G, Pavlidis N, Paraskevaidis E, Ioannidis JP. Survival benefits with diverse chemotherapy regimens for ovarian cancer: meta-analysis of multiple treatments. J Natl Cancer Inst. 2006 Nov 15; 98(22):1655-63.
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  307. Pakos EE, Trikalinos TA, Fotopoulos AD, Ioannidis JP. Prosthesis infection: diagnosis after total joint arthroplasty with antigranulocyte scintigraphy with 99mTc-labeled monoclonal antibodies--a meta-analysis. Radiology. 2007 Jan; 242(1):101-8.
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  308. Elbaz A, Nelson LM, Payami H, Ioannidis JP, Fiske BK, Annesi G, Carmine Belin A, Factor SA, Ferrarese C, Hadjigeorgiou GM, Higgins DS, Kawakami H, Krüger R, Marder KS, Mayeux RP, Mellick GD, Nutt JG, Ritz B, Samii A, Tanner CM, Van Broeckhoven C, Van Den Eeden SK, Wirdefeldt K, Zabetian CP, Dehem M, Montimurro JS, Southwick A, Myers RM, Trikalinos TA. Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurol. 2006 Nov; 5(11):917-23.
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  309. Ioannidis JP. Indirect comparisons: the mesh and mess of clinical trials. Lancet. 2006 Oct 28; 368(9546):1470-2.
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  310. Hernández AV, Westerhout CM, Steyerberg EW, Ioannidis JP, Bueno H, White H, Theroux P, Moliterno DJ, Armstrong PW, Califf RM, Wallentin LC, Simoons ML, Boersma E. Effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST segment elevation acute coronary syndromes: benefit and harm in different age subgroups. Heart. 2007 Apr; 93(4):450-5.
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  311. Ioannidis JP. Common genetic variants for breast cancer: 32 largely refuted candidates and larger prospects. J Natl Cancer Inst. 2006 Oct 4; 98(19):1350-3.
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  312. Ioannidis JP. Gene expression profiling for individualized breast cancer chemotherapy: success or not? Nat Clin Pract Oncol. 2006 Oct; 3(10):538-9.
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  313. Fang Y, Rivadeneira F, van Meurs JB, Pols HA, Ioannidis JP, Uitterlinden AG. Vitamin D receptor gene BsmI and TaqI polymorphisms and fracture risk: a meta-analysis. Bone. 2006 Oct; 39(4):938-45.
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  314. Contopoulos-Ioannidis DG, Alexiou GA, Gouvias TC, Ioannidis JP. An empirical evaluation of multifarious outcomes in pharmacogenetics: beta-2 adrenoceptor gene polymorphisms in asthma treatment. Pharmacogenet Genomics. 2006 Oct; 16(10):705-11.
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  315. Mauri D, Pavlidis N, Polyzos NP, Ioannidis JP. Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis. J Natl Cancer Inst. 2006 Sep 20; 98(18):1285-91.
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  316. Lau J, Ioannidis JP, Terrin N, Schmid CH, Olkin I. The case of the misleading funnel plot. BMJ. 2006 Sep 16; 333(7568):597-600.
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  317. Toumpoulis IK, Anagnostopoulos CE, Ioannidis JP, Toumpoulis SK, Chamogeorgakis T, Swistel DG, Derose JJ. The importance of independent risk-factors for long-term mortality prediction after cardiac surgery. Eur J Clin Invest. 2006 Sep; 36(9):599-607.
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  318. Ioannidis JP, Kavvoura FK. Concordance of functional in vitro data and epidemiological associations in complex disease genetics. Genet Med. 2006 Sep; 8(9):583-93.
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  319. Papanikolaou PN, Christidi GD, Ioannidis JP. Patient outcomes with teaching versus nonteaching healthcare: a systematic review. PLoS Med. 2006 Sep; 3(9):e341.
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  320. Uitterlinden AG, Ralston SH, Brandi ML, Carey AH, Grinberg D, Langdahl BL, Lips P, Lorenc R, Obermayer-Pietsch B, Reeve J, Reid DM, Amedei A, Amidei A, Bassiti A, Bustamante M, Husted LB, Diez-Perez A, Dobnig H, Dunning AM, Enjuanes A, Fahrleitner-Pammer A, Fang Y, Karczmarewicz E, Kruk M, van Leeuwen JP, Mavilia C, van Meurs JB, Mangion J, McGuigan FE, Pols HA, Renner W, Rivadeneira F, van Schoor NM, Scollen S, Sherlock RE, Ioannidis JP. The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis. Ann Intern Med. 2006 Aug 15; 145(4):255-64.
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  321. Maraganore DM, de Andrade M, Elbaz A, Farrer MJ, Ioannidis JP, Krüger R, Rocca WA, Schneider NK, Lesnick TG, Lincoln SJ, Hulihan MM, Aasly JO, Ashizawa T, Chartier-Harlin MC, Checkoway H, Ferrarese C, Hadjigeorgiou G, Hattori N, Kawakami H, Lambert JC, Lynch T, Mellick GD, Papapetropoulos S, Parsian A, Quattrone A, Riess O, Tan EK, Van Broeckhoven C. Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. JAMA. 2006 Aug 9; 296(6):661-70.
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  322. Ioannidis JP, Trikalinos TA, Zintzaras E. Extreme between-study homogeneity in meta-analyses could offer useful insights. J Clin Epidemiol. 2006 Oct; 59(10):1023-32.
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  323. Ioannidis JP, Trikalinos TA, Khoury MJ. Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am J Epidemiol. 2006 Oct 1; 164(7):609-14.
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  324. Zintzaras E, Kitsios G, Harrison GA, Laivuori H, Kivinen K, Kere J, Messinis I, Stefanidis I, Ioannidis JP. Heterogeneity-based genome search meta-analysis for preeclampsia. Hum Genet. 2006 Oct; 120(3):360-70.
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  325. Tiihonen J, Wahlbeck K, Lönnqvist J, Klaukka T, Ioannidis JP, Volavka J, Haukka J. Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up study. BMJ. 2006 Jul 29; 333(7561):224.
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  326. Evangelou E, Trikalinos TA, Salanti G, Ioannidis JP. Family-based versus unrelated case-control designs for genetic associations. PLoS Genet. 2006 Aug; 2(8):e123.
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  327. Mantzavinis GD, Trikalinos TA, Dimoliatis ID, Ioannidis JP. Self-reported health in high and very high incomes. Qual Life Res. 2006 Apr; 15(3):547-58.
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  328. Patsopoulos NA, Ioannidis JP, Analatos AA. Origin and funding of the most frequently cited papers in medicine: database analysis. BMJ. 2006 May 6; 332(7549):1061-4.
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  329. Ioannidis JP. Commentary: grading the credibility of molecular evidence for complex diseases. Int J Epidemiol. 2006 Jun; 35(3):572-8; discussion 593-6.
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  330. Papanikolaou PN, Christidi GD, Ioannidis JP. Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies. CMAJ. 2006 Feb 28; 174(5):635-41.
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  331. Ralston SH, Uitterlinden AG, Brandi ML, Balcells S, Langdahl BL, Lips P, Lorenc R, Obermayer-Pietsch B, Scollen S, Bustamante M, Husted LB, Carey AH, Diez-Perez A, Dunning AM, Falchetti A, Karczmarewicz E, Kruk M, van Leeuwen JP, van Meurs JB, Mangion J, McGuigan FE, Mellibovsky L, del Monte F, Pols HA, Reeve J, Reid DM, Renner W, Rivadeneira F, van Schoor NM, Sherlock RE, Ioannidis JP. Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study. PLoS Med. 2006 Apr; 3(4):e90.
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  332. Ioannidis JP, Mulrow CD, Goodman SN. Adverse events: the more you search, the more you find. Ann Intern Med. 2006 Feb 21; 144(4):298-300.
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  333. Trikalinos TA, Salanti G, Khoury MJ, Ioannidis JP. Impact of violations and deviations in Hardy-Weinberg equilibrium on postulated gene-disease associations. Am J Epidemiol. 2006 Feb 15; 163(4):300-9.
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  334. Polyzos NP, Pavlidis N, Paraskevaidis E, Ioannidis JP. Randomized evidence on chemotherapy and hormonal therapy regimens for advanced endometrial cancer: an overview of survival data. Eur J Cancer. 2006 Feb; 42(3):319-26.
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  335. Karassa FB, Afeltra A, Ambrozic A, Chang DM, De Keyser F, Doria A, Galeazzi M, Hirohata S, Hoffman IE, Inanc M, Massardo L, Mathieu A, Mok CC, Morozzi G, Sanna G, Spindler AJ, Tzioufas AG, Yoshio T, Ioannidis JP. Accuracy of anti-ribosomal P protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus: an international meta-analysis. Arthritis Rheum. 2006 Jan; 54(1):312-24.
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  336. Trikalinos TA, Karvouni A, Zintzaras E, Ylisaukko-oja T, Peltonen L, Järvelä I, Ioannidis JP. A heterogeneity-based genome search meta-analysis for autism-spectrum disorders. Mol Psychiatry. 2006 Jan; 11(1):29-36.
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  337. Ioannidis JP, Gwinn M, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam A, Danesh J, Smith GD, Dolan S, Duncan R, Gruis NA, Hartge P, Hashibe M, Hunter DJ, Jarvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, O'Brien TR, Petersen G, Riboli E, Salanti G, Seminara D, Smeeth L, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham N, Winn DM, Zimmern R, Khoury MJ. A road map for efficient and reliable human genome epidemiology. Nat Genet. 2006 Jan; 38(1):3-5.
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  338. Ioannidis JP. Journals should publish all "null" results and should sparingly publish "positive" results. Cancer Epidemiol Biomarkers Prev. 2006 Jan; 15(1):186.
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  339. Evangelou E, Trikalinos TA, Ioannidis JP. Unavailability of online supplementary scientific information from articles published in major journals. FASEB J. 2005 Dec; 19(14):1943-4.
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  340. Pan Z, Trikalinos TA, Kavvoura FK, Lau J, Ioannidis JP. Local literature bias in genetic epidemiology: an empirical evaluation of the Chinese literature. PLoS Med. 2005 Dec; 2(12):e334.
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  341. Telenti A, Ioannidis JP. Susceptibility to HIV infection--disentangling host genetics and host behavior. J Infect Dis. 2006 Jan 1; 193(1):4-6.
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  342. Ioannidis JP. Why most published research findings are false. PLoS Med. 2005 Aug; 2(8):e124.
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  343. Trikalinos TA, Panidou ET, Ioannidis JP. Reply to Badri et al. on 'Limited benefit of antiretroviral resistance testing in treatment-experienced patients: a meta-analysis'. AIDS. 2005 Aug 12; 19(12):1336-7.
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  344. Polycarpou A, Papanikolaou P, Ioannidis JP, Contopoulos-Ioannidis DG. Anticonvulsants for alcohol withdrawal. Cochrane Database Syst Rev. 2005; (3):CD005064.
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  345. Ntais C, Pakos E, Kyzas P, Ioannidis JP. Benzodiazepines for alcohol withdrawal. Cochrane Database Syst Rev. 2005; (3):CD005063.
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  346. Kyzas PA, Loizou KT, Ioannidis JP. Selective reporting biases in cancer prognostic factor studies. J Natl Cancer Inst. 2005 Jul 20; 97(14):1043-55.
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  347. Ioannidis JP, Bernstein J, Boffetta P, Danesh J, Dolan S, Hartge P, Hunter D, Inskip P, Jarvelin MR, Little J, Maraganore DM, Bishop JA, O'Brien TR, Petersen G, Riboli E, Seminara D, Taioli E, Uitterlinden AG, Vineis P, Winn DM, Salanti G, Higgins JP, Khoury MJ. A network of investigator networks in human genome epidemiology. Am J Epidemiol. 2005 Aug 15; 162(4):302-4.
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  348. Ioannidis JP. Contradicted and initially stronger effects in highly cited clinical research. JAMA. 2005 Jul 13; 294(2):218-28.
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  349. Kavvoura FK, Ioannidis JP. CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE Review and meta-analysis. Am J Epidemiol. 2005 Jul 1; 162(1):3-16.
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  350. Salanti G, Amountza G, Ntzani EE, Ioannidis JP. Hardy-Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations, and power. Eur J Hum Genet. 2005 Jul; 13(7):840-8.
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  351. Swingler GH, Pillay V, Pienaar ED, Ioannidis JP. International collaboration, funding and association with burden of disease in randomized controlled trials in Africa. Bull World Health Organ. 2005 Jul; 83(7):511-7.
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  352. Zintzaras E, Ioannidis JP. HEGESMA: genome search meta-analysis and heterogeneity testing. Bioinformatics. 2005 Sep 15; 21(18):3672-3.
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  353. Ioannidis JP, Karvouni E, Katritsis DG. Creatine kinase-MB elevation following stent implantation. J Am Coll Cardiol. 2005 Jun 7; 45(11):1908; author reply 1908-9.
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  354. Ioannidis J, Wilkinson D. HIV: prevention of opportunistic infections. Clin Evid. 2005 Jun; (13):834-53.
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  355. Pakos EE, Fotopoulos AD, Ioannidis JP. 18F-FDG PET for evaluation of bone marrow infiltration in staging of lymphoma: a meta-analysis. J Nucl Med. 2005 Jun; 46(6):958-63.
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  356. Katritsis DG, Ioannidis JP. Percutaneous coronary intervention versus conservative therapy in nonacute coronary artery disease: a meta-analysis. Circulation. 2005 Jun 7; 111(22):2906-12.
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  357. Patsopoulos NA, Analatos AA, Ioannidis JP. Relative citation impact of various study designs in the health sciences. JAMA. 2005 May 18; 293(19):2362-6.
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  358. Sotiriadis A, Makrydimas G, Papatheodorou S, Ioannidis JP. Expectant, medical, or surgical management of first-trimester miscarriage: a meta-analysis. Obstet Gynecol. 2005 May; 105(5 Pt 1):1104-13.
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  359. Mantzavinis GD, Pappas N, Dimoliatis ID, Ioannidis JP. Multivariate models of self-reported health often neglected essential candidate determinants and methodological issues. J Clin Epidemiol. 2005 May; 58(5):436-43.
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  360. Contopoulos-Ioannidis DG, Manoli EN, Ioannidis JP. Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes. J Allergy Clin Immunol. 2005 May; 115(5):963-72.
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  361. Ioannidis JP, Trikalinos TA. Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials. J Clin Epidemiol. 2005 Jun; 58(6):543-9.
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  362. Contopoulos-Ioannidis DG, Gilbody SM, Trikalinos TA, Churchill R, Wahlbeck K, Ioannidis JP. Comparison of large versus smaller randomized trials for mental health-related interventions. Am J Psychiatry. 2005 Mar; 162(3):578-84.
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  363. Katritsis DG, Karvouni E, Ioannidis JP. Meta-analysis comparing drug-eluting stents with bare metal stents. Am J Cardiol. 2005 Mar 1; 95(5):640-3.
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  364. Karassa FB, Matsagas MI, Schmidt WA, Ioannidis JP. Meta-analysis: test performance of ultrasonography for giant-cell arteritis. Ann Intern Med. 2005 Mar 1; 142(5):359-69.
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  365. Patsopoulos NA, Ntzani EE, Zintzaras E, Ioannidis JP. CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: a meta-analysis. Pharmacogenet Genomics. 2005 Mar; 15(3):151-8.
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  366. Kyzas PA, Cunha IW, Ioannidis JP. Prognostic significance of vascular endothelial growth factor immunohistochemical expression in head and neck squamous cell carcinoma: a meta-analysis. Clin Cancer Res. 2005 Feb 15; 11(4):1434-40.
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  367. Mauri D, Pavlidis N, Ioannidis JP. Neoadjuvant versus adjuvant systemic treatment in breast cancer: a meta-analysis. J Natl Cancer Inst. 2005 Feb 2; 97(3):188-94.
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  368. Zintzaras E, Ioannidis JP. Heterogeneity testing in meta-analysis of genome searches. Genet Epidemiol. 2005 Feb; 28(2):123-37.
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  369. O'Neil-Callahan K, Katsimaglis G, Tepper MR, Ryan J, Mosby C, Ioannidis JP, Danias PG. Statins decrease perioperative cardiac complications in patients undergoing noncardiac vascular surgery: the Statins for Risk Reduction in Surgery (StaRRS) study. J Am Coll Cardiol. 2005 Feb 1; 45(3):336-42.
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  370. DeRose JJ, Toumpoulis IK, Balaram SK, Ioannidis JP, Belsley S, Ashton RC, Swistel DG, Anagnostopoulos CE. Preoperative prediction of long-term survival after coronary artery bypass grafting in patients with low left ventricular ejection fraction. J Thorac Cardiovasc Surg. 2005 Feb; 129(2):314-21.
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  371. Ioannidis JP. Microarrays and molecular research: noise discovery? Lancet. 2005 Feb 5-11; 365(9458):454-5.
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  372. Ioannidis JP. Molecular bias. Eur J Epidemiol. 2005; 20(9):739-45.
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  373. Ioannidis JP, Vlachoyiannopoulos PG, Haidich AB, Medsger TA, Lucas M, Michet CJ, Kuwana M, Yasuoka H, van den Hoogen F, Te Boome L, van Laar JM, Verbeet NL, Matucci-Cerinic M, Georgountzos A, Moutsopoulos HM. Mortality in systemic sclerosis: an international meta-analysis of individual patient data. Am J Med. 2005 Jan; 118(1):2-10.
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  374. Ntais C, Polycarpou A, Ioannidis JP. Association of GSTM1, GSTT1, and GSTP1 gene polymorphisms with the risk of prostate cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2005 Jan; 14(1):176-81.
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  375. Makrydimas G, Sotiriadis A, Huggon IC, Simpson J, Sharland G, Carvalho JS, Daubeney PE, Ioannidis JP. Nuchal translucency and fetal cardiac defects: a pooled analysis of major fetal echocardiography centers. Am J Obstet Gynecol. 2005 Jan; 192(1):89-95.
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  376. Berger VW, Ioannidis JP. The Decameron of poor research. BMJ. 2004 Dec 18; 329(7480):1436-40.
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  377. Kavvoura FK, Ioannidis JP. Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis. Hum Genet. 2005 Feb; 116(3):192-9.
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  378. Economou M, Trikalinos TA, Loizou KT, Tsianos EV, Ioannidis JP. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol. 2004 Dec; 99(12):2393-404.
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  379. Ioannidis JP, Evans SJ, Gøtzsche PC, O'Neill RT, Altman DG, Schulz K, Moher D. Better reporting of harms in randomized trials: an extension of the CONSORT statement. Ann Intern Med. 2004 Nov 16; 141(10):781-8.
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  380. Ioannidis JP, Ntzani EE, Trikalinos TA. 'Racial' differences in genetic effects for complex diseases. Nat Genet. 2004 Dec; 36(12):1312-8.
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  381. Panidou ET, Trikalinos TA, Ioannidis JP. Limited benefit of antiretroviral resistance testing in treatment-experienced patients: a meta-analysis. AIDS. 2004 Nov 5; 18(16):2153-61.
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  382. Ioannidis JP, Ralston SH, Bennett ST, Brandi ML, Grinberg D, Karassa FB, Langdahl B, van Meurs JB, Mosekilde L, Scollen S, Albagha OM, Bustamante M, Carey AH, Dunning AM, Enjuanes A, van Leeuwen JP, Mavilia C, Masi L, McGuigan FE, Nogues X, Pols HA, Reid DM, Schuit SC, Sherlock RE, Uitterlinden AG. Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes. JAMA. 2004 Nov 3; 292(17):2105-14.
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  383. Danias PG, Roussakis A, Ioannidis JP. Diagnostic performance of coronary magnetic resonance angiography as compared against conventional X-ray angiography: a meta-analysis. J Am Coll Cardiol. 2004 Nov 2; 44(9):1867-76.
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  384. Contopoulos-Ioannidis DG, Ioannidis JP. Treatment options for acute sinusitis in children. Curr Allergy Asthma Rep. 2004 Nov; 4(6):471-7.
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  385. Trikalinos TA, Churchill R, Ferri M, Leucht S, Tuunainen A, Wahlbeck K, Ioannidis JP. Effect sizes in cumulative meta-analyses of mental health randomized trials evolved over time. J Clin Epidemiol. 2004 Nov; 57(11):1124-30.
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  386. Pakos EE, Ioannidis JP. Radiotherapy vs. nonsteroidal anti-inflammatory drugs for the prevention of heterotopic ossification after major hip procedures: a meta-analysis of randomized trials. Int J Radiat Oncol Biol Phys. 2004 Nov 1; 60(3):888-95.
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  387. Papanikolaou PN, Ioannidis JP. Availability of large-scale evidence on specific harms from systematic reviews of randomized trials. Am J Med. 2004 Oct 15; 117(8):582-9.
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  388. Ioannidis JP. Large scale evidence and replication: insights from rheumatology and beyond. Ann Rheum Dis. 2005 Mar; 64(3):345-6.
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  389. Pakos EE, Kyzas PA, Ioannidis JP. Prognostic significance of TP53 tumor suppressor gene expression and mutations in human osteosarcoma: a meta-analysis. Clin Cancer Res. 2004 Sep 15; 10(18 Pt 1):6208-14.
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  390. Kosmas IP, Tatsioni A, Ioannidis JP. Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis. J Hypertens. 2004 Sep; 22(9):1655-62.
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  391. Vlachoyiannopoulos PG, Ioannidis JP. Cyclophosphamide in systemic sclerosis: light and shadows. Clin Exp Rheumatol. 2004 Sep-Oct; 22(5):551-2.
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  392. Papanikolaou PN, Churchill R, Wahlbeck K, Ioannidis JP. Safety reporting in randomized trials of mental health interventions. Am J Psychiatry. 2004 Sep; 161(9):1692-7.
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  393. Trikalinos TA, Ntzani EE, Contopoulos-Ioannidis DG, Ioannidis JP. Establishment of genetic associations for complex diseases is independent of early study findings. Eur J Hum Genet. 2004 Sep; 12(9):762-9.
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  394. Gouva C, Nikolopoulos P, Ioannidis JP, Siamopoulos KC. Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial. Kidney Int. 2004 Aug; 66(2):753-60.
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  395. Kent DM, Mwamburi DM, Bennish ML, Kupelnick B, Ioannidis JP. Clinical trials in sub-Saharan Africa and established standards of care: a systematic review of HIV, tuberculosis, and malaria trials. JAMA. 2004 Jul 14; 292(2):237-42.
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  396. Contopoulos-Ioannidis DG, Giotis ND, Baliatsa DV, Ioannidis JP. Extended-interval aminoglycoside administration for children: a meta-analysis. Pediatrics. 2004 Jul; 114(1):e111-8.
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  397. Vranos G, Tatsioni A, Polyzoidis K, Ioannidis JP. Randomized trials of neurosurgical interventions: a systematic appraisal. Neurosurgery. 2004 Jul; 55(1):18-25; discussion 25-6.
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  398. Karassa FB, Trikalinos TA, Ioannidis JP. The role of FcgammaRIIA and IIIA polymorphisms in autoimmune diseases. Biomed Pharmacother. 2004 Jun; 58(5):286-91.
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  399. Ioannidis JP. The value of meta-analysis in rheumatology research. Autoimmun Rev. 2004 Jun; 3 Suppl 1:S57-9.
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  400. Ioannidis JP. Global estimates of high-level brain drain and deficit. FASEB J. 2004 Jun; 18(9):936-9.
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  401. Maraganore DM, Lesnick TG, Elbaz A, Chartier-Harlin MC, Gasser T, Krüger R, Hattori N, Mellick GD, Quattrone A, Satoh J, Toda T, Wang J, Ioannidis JP, de Andrade M, Rocca WA, Toda T. UCHL1 is a Parkinson's disease susceptibility gene. Ann Neurol. 2004 Apr; 55(4):512-21.
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  402. Haidich AB, Ioannidis JP. The Gini coefficient as a measure for understanding accrual inequalities in multicenter clinical studies. J Clin Epidemiol. 2004 Apr; 57(4):341-8.
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  403. Ntais C, Polycarpou A, Ioannidis JP. Meta-analysis of the association of the cathepsin D Ala224Val gene polymorphism with the risk of Alzheimer's disease: a HuGE gene-disease association review. Am J Epidemiol. 2004 Mar 15; 159(6):527-36.
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  404. Ziavra N, Kastanioudakis I, Trikalinos TA, Skevas A, Ioannidis JP. Diagnosis of sensorineural hearing loss with neural networks versus logistic regression modeling of distortion product otoacoustic emissions. Audiol Neurootol. 2004 Mar-Apr; 9(2):81-7.
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  405. Ioannidis JP, Tatsioni A, Abrams EJ, Bulterys M, Coombs RW, Goedert JJ, Korber BT, Mayaux MJ, Mofenson LM, Moye J, Newell ML, Shapiro DE, Teglas JP, Thompson B, Wiener J. Maternal viral load and rate of disease progression among vertically HIV-1-infected children: an international meta-analysis. AIDS. 2004 Jan 2; 18(1):99-108.
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  406. Carr DB, Goudas LC, Balk EM, Bloch R, Ioannidis JP, Lau J. Evidence report on the treatment of pain in cancer patients. J Natl Cancer Inst Monogr. 2004; (32):23-31.
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  407. Ioannidis JP. Physical examination. Lancet. 2003 Dec 13; 362(9400):2023; author reply 2024.
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  408. Ntais C, Polycarpou A, Ioannidis JP. Vitamin D receptor gene polymorphisms and risk of prostate cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2003 Dec; 12(12):1395-402.
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  409. Rizos E, Drosos AA, Ioannidis JP. Isolated intraparotid Kaposi sarcoma in human immunodeficiency virus type 1 infection. Mayo Clin Proc. 2003 Dec; 78(12):1561-3.
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  410. Ioannidis J, Wilkinson D. HIV: prevention of opportunistic infections. Clin Evid. 2003 Dec; (10):809-30.
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  411. Swingler GH, Volmink J, Ioannidis JP. Number of published systematic reviews and global burden of disease: database analysis. BMJ. 2003 Nov 8; 327(7423):1083-4.
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  412. Menu E, Scarlatti G, Barré-Sinoussi F, Gray G, Bollinger B, Ioannidis JP, Miotti P, Osborne C. Mother-to-child transmission of HIV: developing integration of healthcare programmes with clinical, social and basic research studies. Report of the International Workshop held at Chobe Marina Lodge, Kasane, Botswana, 21-25 January 2003. Acta Paediatr. 2003 Nov; 92(11):1343-8.
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  413. Ioannidis JP, Polycarpou A, Ntais C, Pavlidis N. Randomised trials comparing chemotherapy regimens for advanced non-small cell lung cancer: biases and evolution over time. Eur J Cancer. 2003 Nov; 39(16):2278-87.
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  414. Makrydimas G, Sotiriadis A, Ioannidis JP. Screening performance of first-trimester nuchal translucency for major cardiac defects: a meta-analysis. Am J Obstet Gynecol. 2003 Nov; 189(5):1330-5.
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  415. Ntzani EE, Ioannidis JP. Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment. Lancet. 2003 Nov 1; 362(9394):1439-44.
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  416. Isaakidis P, Ioannidis JP. Evaluation of cluster randomized controlled trials in sub-Saharan Africa. Am J Epidemiol. 2003 Nov 1; 158(9):921-6.
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  417. Zintzaras E, Ioannidis JP. Modelling of escalating outpatient antibiotic expenditures. J Antimicrob Chemother. 2003 Dec; 52(6):1001-4.
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  418. Ioannidis JP, Karvouni E, Katritsis DG. Mortality risk conferred by small elevations of creatine kinase-MB isoenzyme after percutaneous coronary intervention. J Am Coll Cardiol. 2003 Oct 15; 42(8):1406-11.
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  419. Ioannidis JP, Trikalinos TA, Law M, Carr A. HIV lipodystrophy case definition using artificial neural network modelling. Antivir Ther. 2003 Oct; 8(5):435-41.
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  420. Pakos EE, Ioannidis JP. The association of P-glycoprotein with response to chemotherapy and clinical outcome in patients with osteosarcoma. A meta-analysis. Cancer. 2003 Aug 1; 98(3):581-9.
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  421. Ioannidis JP, Contopoulos-Ioannidis DG, Rosenberg PS, Goedert JJ, De Rossi A, Espanol T, Frenkel L, Mayaux MJ, Newell ML, Pahwa SG, Rousseau C, Scarlatti G, Sei S, Sen L, O'Brien TR. Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis. AIDS. 2003 Jul 25; 17(11):1631-8.
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  422. Ntais C, Polycarpou A, Ioannidis JP. SRD5A2 gene polymorphisms and the risk of prostate cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2003 Jul; 12(7):618-24.
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  423. Kosmas IP, Tatsioni A, Ioannidis JP. Association of Leiden mutation in factor V gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis. J Hypertens. 2003 Jul; 21(7):1221-8.
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  424. Karassa FB, Bijl M, Davies KA, Kallenberg CG, Khamashta MA, Manger K, Michel M, Piette JC, Salmon JE, Song YW, Tsuchiya N, Yoo DH, Ioannidis JP. Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: an international meta-analysis. Arthritis Rheum. 2003 Jul; 48(7):1930-8.
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  425. Kent DM, McGrath D, Ioannidis JP, Bennish ML. Suitable monitoring approaches to antiretroviral therapy in resource-poor settings: setting the research agenda. Clin Infect Dis. 2003 Jul 1; 37(Suppl 1):S13-24.
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  426. Ioannidis J, Wilkinson D. HIV: opportunistic infections. Clin Evid. 2003 Jun; (9):795-816.
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  427. Ioannidis JP, Pavlidis N. Levels of absolute survival benefit for systemic therapies of advanced cancer. a call for standards. Eur J Cancer. 2003 Jun; 39(9):1194-8.
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  428. Ioannidis JP, Lau J. 18F-FDG PET for the diagnosis and grading of soft-tissue sarcoma: a meta-analysis. J Nucl Med. 2003 May; 44(5):717-24.
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  429. Vlachoyiannopoulos PG, Kanellopoulos PG, Ioannidis JP, Tektonidou MG, Mastorakou I, Moutsopoulos HM. Atherosclerosis in premenopausal women with antiphospholipid syndrome and systemic lupus erythematosus: a controlled study. Rheumatology (Oxford). 2003 May; 42(5):645-51.
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  430. Haidich AB, Ioannidis JP. Late-starter sites in randomized controlled trials. J Clin Epidemiol. 2003 May; 56(5):408-15.
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  431. Sotiriadis A, Makrydimas G, Ioannidis JP. Diagnostic performance of intracardiac echogenic foci for Down syndrome: a meta-analysis. Obstet Gynecol. 2003 May; 101(5 Pt 1):1009-16.
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  432. Karassa FB, Tatsioni A, Ioannidis JP. Design, quality, and bias in randomized controlled trials of systemic lupus erythematosus. J Rheumatol. 2003 May; 30(5):979-84.
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  433. Contopoulos-Ioannidis DG, Ntzani E, Ioannidis JP. Translation of highly promising basic science research into clinical applications. Am J Med. 2003 Apr 15; 114(6):477-84.
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  434. Ioannidis JP. Genetic associations: false or true? Trends Mol Med. 2003 Apr; 9(4):135-8.
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  435. Karassa FB, Trikalinos TA, Ioannidis JP. The Fc gamma RIIIA-F158 allele is a risk factor for the development of lupus nephritis: a meta-analysis. Kidney Int. 2003 Apr; 63(4):1475-82.
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  436. Papanikolaou PN, Ioannidis JP. Awareness of the side effects of possessed medications in a community setting. Eur J Clin Pharmacol. 2003 Apr; 58(12):821-7.
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  437. Ioannidis JP, Trikalinos TA, Ntzani EE, Contopoulos-Ioannidis DG. Genetic associations in large versus small studies: an empirical assessment. Lancet. 2003 Feb 15; 361(9357):567-71.
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  438. Mulherin SA, O'Brien TR, Ioannidis JP, Goedert JJ, Buchbinder SP, Coutinho RA, Jamieson BD, Meyer L, Michael NL, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Theodorou ID, Vlahov D, Rosenberg PS. Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection. AIDS. 2003 Feb 14; 17(3):377-87.
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  439. Ioannidis JP, Katsifis GE, Stavropoulos ED, Manoussakis MN, Moutsopoulos HM. Evaluation of the association of autoantibodies with mortality in the very elderly: a cohort study. Rheumatology (Oxford). 2003 Feb; 42(2):357-61.
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  440. Rizos E, Drosos AA, Ioannidis JP. Nail pigmentation and fatigue in a 39-year-old woman. Clin Infect Dis. 2003 Feb 1; 36(3):348, 378-9.
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  441. Ntais C, Polycarpou A, Ioannidis JP. Association of the CYP17 gene polymorphism with the risk of prostate cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2003 Feb; 12(2):120-6.
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  442. Drossos GE, Toumpoulis IK, Katritsis DG, Ioannidis JP, Kontogiorgi P, Svarna E, Anagnostopoulos CE. Is vitamin C superior to diltiazem for radial artery vasodilation in patients awaiting coronary artery bypass grafting? J Thorac Cardiovasc Surg. 2003 Feb; 125(2):330-5.
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  443. Kapitsinou PP, Ioannidis JP, Boletis JN, Sotsiou F, Nakopoulou L, Daphnis E, Moutsopoulos HM. Clinicopathologic predictors of death and ESRD in patients with pauci-immune necrotizing glomerulonephritis. Am J Kidney Dis. 2003 Jan; 41(1):29-37.
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  444. Tatsioni A, Gerasi E, Charitidou E, Simou N, Mavreas V, Ioannidis JP. Important drug safety information on the internet: assessing its accuracy and reliability. Drug Saf. 2003; 26(7):519-27.
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  445. Contopoulos-Ioannidis DG, O'Brien TR, Goedert JJ, Rosenberg PS, Ioannidis JP. Effect of CCR5-delta32 heterozygosity on the risk of perinatal HIV-1 infection: a meta-analysis. J Acquir Immune Defic Syndr. 2003 Jan 1; 32(1):70-6.
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  446. Karvouni E, Katritsis DG, Ioannidis JP. Intravenous glycoprotein IIb/IIIa receptor antagonists reduce mortality after percutaneous coronary interventions. J Am Coll Cardiol. 2003 Jan 1; 41(1):26-32.
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  447. Contopoulos-Ioannidis DG, Ioannidis JP, Lau J. Acute sinusitis in children: current treatment strategies. Paediatr Drugs. 2003; 5(2):71-80.
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  448. Ioannidis JP, Stavrou I, Trikalinos TA, Zois C, Brandi ML, Gennari L, Albagha O, Ralston SH, Tsatsoulis A. Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women: a meta-analysis. J Bone Miner Res. 2002 Nov; 17(11):2048-60.
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  449. Ioannidis JP, Katsifis GE, Tzioufas AG, Moutsopoulos HM. Predictors of sustained amenorrhea from pulsed intravenous cyclophosphamide in premenopausal women with systemic lupus erythematosus. J Rheumatol. 2002 Oct; 29(10):2129-35.
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  450. Katritsis D, Ioannidis JP, Giazitzoglou E, Korovesis S, Anagnostopoulos CE, Camm AJ. Conduction delay within the coronary sinus in humans: implications for atrial arrhythmias. J Cardiovasc Electrophysiol. 2002 Sep; 13(9):859-62.
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  451. Ioannidis JP, Rosenberg PS, Goedert JJ, O'Brien TR. Commentary: meta-analysis of individual participants' data in genetic epidemiology. Am J Epidemiol. 2002 Aug 1; 156(3):204-10.
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  452. Polycarpou A, Ntais C, Korber BT, Elrich HA, Winchester R, Krogstad P, Wolinsky S, Rostron T, Rowland-Jones SL, Ammann AJ, Ioannidis JP. Association between maternal and infant class I and II HLA alleles and of their concordance with the risk of perinatal HIV type 1 transmission. AIDS Res Hum Retroviruses. 2002 Jul 20; 18(11):741-6.
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  453. Katsifis GE, Tzioufas AG, Vlachoyiannopoulos PG, Voulgarelis M, Moutsopoulos HM, Ioannidis JP. Risk of myelotoxicity with intravenous cyclophosphamide in patients with systemic lupus erythematosus. Rheumatology (Oxford). 2002 Jul; 41(7):780-6.
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  454. Ioannidis JP, Trikalinos TA, Danias PG. Electrocardiogram-gated single-photon emission computed tomography versus cardiac magnetic resonance imaging for the assessment of left ventricular volumes and ejection fraction: a meta-analysis. J Am Coll Cardiol. 2002 Jun 19; 39(12):2059-68.
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  455. Balk EM, Bonis PA, Moskowitz H, Schmid CH, Ioannidis JP, Wang C, Lau J. Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trials. JAMA. 2002 Jun 12; 287(22):2973-82.
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  456. Ioannidis JP, Chew P, Lau J. Standardized retrieval of side effects data for meta-analysis of safety outcomes. A feasibility study in acute sinusitis. J Clin Epidemiol. 2002 Jun; 55(6):619-26.
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  457. Ioannidis J, Wilkinson D. Opportunistic infections and HIV. Clin Evid. 2002 Jun; (7):717-37.
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  458. Karassa FB, Trikalinos TA, Ioannidis JP. Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis. Arthritis Rheum. 2002 Jun; 46(6):1563-71.
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  459. Ioannidis JP, Tarassi K, Papadopoulos IA, Voulgari PV, Boki KA, Papasteriades CA, Drosos AA. Shared epitopes and rheumatoid arthritis: disease associations in Greece and meta-analysis of Mediterranean European populations. Semin Arthritis Rheum. 2002 Jun; 31(6):361-70.
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  460. Giannakakis IA, Haidich AB, Contopoulos-Ioannidis DG, Papanikolaou GN, Baltogianni MS, Ioannidis JP. Citation of randomized evidence in support of guidelines of therapeutic and preventive interventions. J Clin Epidemiol. 2002 Jun; 55(6):545-55.
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  461. Stavrou I, Zois C, Ioannidis JP, Tsatsoulis A. Association of polymorphisms of the oestrogen receptor alpha gene with the age of menarche. Hum Reprod. 2002 Apr; 17(4):1101-5.
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  462. Spoulou V, Gilks CF, Ioannidis JP. Protein conjugate pneumococcal vaccines. BMJ. 2002 Mar 30; 324(7340):750-1.
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  463. Isaakidis P, Swingler GH, Pienaar E, Volmink J, Ioannidis JP. Relation between burden of disease and randomised evidence in sub-Saharan Africa: survey of research. BMJ. 2002 Mar 23; 324(7339):702.
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  464. Ioannidis JP, Vassiliou VA, Moutsopoulos HM. Long-term risk of mortality and lymphoproliferative disease and predictive classification of primary Sjögren's syndrome. Arthritis Rheum. 2002 Mar; 46(3):741-7.
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  465. Pakas I, Ioannidis JP, Malagari K, Skopouli FN, Moutsopoulos HM, Vlachoyiannopoulos PG. Cyclophosphamide with low or high dose prednisolone for systemic sclerosis lung disease. J Rheumatol. 2002 Feb; 29(2):298-304.
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  466. Lau J, Balk E, Rothberg M, Ioannidis JP, DeVine D, Chew P, Kupelnick B, Miller K. Management of clinically inapparent adrenal mass. Evid Rep Technol Assess (Summ). 2002 Feb; (56):1-5.
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  467. Kyriakidi M, Ioannidis JP. Design and quality considerations for randomized controlled trials in systemic sclerosis. Arthritis Rheum. 2002 Feb; 47(1):73-81.
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  468. Ioannidis JP, Lau J. Improving safety reporting from randomised trials. Drug Saf. 2002; 25(2):77-84.
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  469. Papanikolaou GN, Ioannidis JP. Declaring competing interests. Types of competing interests would be of interest. BMJ. 2001 Nov 17; 323(7322):1187-8.
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  470. Ioannidis JP, Rosenberg PS, Goedert JJ, Ashton LJ, Benfield TL, Buchbinder SP, Coutinho RA, Eugen-Olsen J, Gallart T, Katzenstein TL, Kostrikis LG, Kuipers H, Louie LG, Mallal SA, Margolick JB, Martinez OP, Meyer L, Michael NL, Operskalski E, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Stewart GJ, Theodorou ID, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury JF, O'Brien TR. Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data. Ann Intern Med. 2001 Nov 6; 135(9):782-95.
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  471. Contopoulos-Ioannidis DG, Ioannidis JP, Chew P, Lau J. Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections. J Antimicrob Chemother. 2001 Nov; 48(5):691-703.
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  472. Haidich AB, Ioannidis JP. Effect of early patient enrollment on the time to completion and publication of randomized controlled trials. Am J Epidemiol. 2001 Nov 1; 154(9):873-80.
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  473. Ioannidis JP, Contopoulos-Ioannidis DG, Chew P, Lau J. Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections. J Antimicrob Chemother. 2001 Nov; 48(5):677-89.
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  474. Ioannidis JP, Ntzani EE, Trikalinos TA, Contopoulos-Ioannidis DG. Replication validity of genetic association studies. Nat Genet. 2001 Nov; 29(3):306-9.
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  475. Trikalinos TA, Ioannidis JP. Discontinuation of Pneumocystis carinii prophylaxis in patients infected with human immunodeficiency virus: a meta-analysis and decision analysis. Clin Infect Dis. 2001 Dec 1; 33(11):1901-9.
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  476. Trikalinos TA, Karassa FB, Ioannidis JP. Meta-analysis of the association between low-affinity Fcgamma receptor gene polymorphisms and hematologic and autoimmune disease. Blood. 2001 Sep 1; 98(5):1634-5.
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  477. Haidich AB, Ioannidis JP. Patterns of patient enrollment in randomized controlled trials. J Clin Epidemiol. 2001 Sep; 54(9):877-83.
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  478. Ioannidis JP, Lau J. Technical report: evidence for the diagnosis and treatment of acute uncomplicated sinusitis in children: a systematic overview. Pediatrics. 2001 Sep; 108(3):E57.
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  479. Efstathiadou Z, Tsatsoulis A, Ioannidis JP. Association of collagen Ialpha 1 Sp1 polymorphism with the risk of prevalent fractures: a meta-analysis. J Bone Miner Res. 2001 Sep; 16(9):1586-92.
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  480. Ioannidis JP, Haidich AB, Pappa M, Pantazis N, Kokori SI, Tektonidou MG, Contopoulos-Ioannidis DG, Lau J. Comparison of evidence of treatment effects in randomized and nonrandomized studies. JAMA. 2001 Aug 15; 286(7):821-30.
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  481. Ioannidis JP, Karassa FB. Bias in uncontrolled therapeutic trials in rheumatology due to selection of populations with extreme characteristics. J Rheumatol. 2001 Aug; 28(8):1881-7.
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  482. Katritsis D, Ioannidis JP, Anagnostopoulos CE, Sarris GE, Giazitzoglou E, Korovesis S, Camm AJ. Identification and catheter ablation of extracardiac and intracardiac components of ligament of Marshall tissue for treatment of paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol. 2001 Jul; 12(7):750-8.
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  483. Tatsioni A, Charchanti A, Kitsiou E, Ioannidis JP. Appendicectomies in Albanians in Greece: outcomes in a highly mobile immigrant patient population. BMC Health Serv Res. 2001; 1:5.
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  484. Haidich AB, Ioannidis JP. Determinants of patient recruitment in a multicenter clinical trials group: trends, seasonality and the effect of large studies. BMC Med Res Methodol. 2001; 1:4.
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  485. Contopoulos-Ioannidis DG, Koliofoti ID, Koutroumpa IC, Giannakakis IA, Ioannidis JP. Pathways for inappropriate dispensing of antibiotics for rhinosinusitis: a randomized trial. Clin Infect Dis. 2001 Jul 1; 33(1):76-82.
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  486. Papanikolaou GN, Baltogianni MS, Contopoulos-Ioannidis DG, Haidich AB, Giannakakis IA, Ioannidis JP. Reporting of conflicts of interest in guidelines of preventive and therapeutic interventions. BMC Med Res Methodol. 2001; 1:3.
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  487. Ioannidis JP, Salem D, Chew PW, Lau J. Accuracy of imaging technologies in the diagnosis of acute cardiac ischemia in the emergency department: a meta-analysis. Ann Emerg Med. 2001 May; 37(5):471-7.
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  488. Ioannidis JP, Salem D, Chew PW, Lau J. Accuracy and clinical effect of out-of-hospital electrocardiography in the diagnosis of acute cardiac ischemia: a meta-analysis. Ann Emerg Med. 2001 May; 37(5):461-70.
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  489. Balk EM, Ioannidis JP, Salem D, Chew PW, Lau J. Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: a meta-analysis. Ann Emerg Med. 2001 May; 37(5):478-94.
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  490. Ioannidis JP, Lau J. Evidence on interventions to reduce medical errors: an overview and recommendations for future research. J Gen Intern Med. 2001 May; 16(5):325-34.
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  491. Katritsis D, Korovesis S, Giazitzoglou E, Parissis J, Kalivas P, Webb-Peploe MM, Ioannidis JP, Haliassos A. C-Reactive protein concentrations and angiographic characteristics of coronary lesions. Clin Chem. 2001 May; 47(5):882-6.
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  492. Lau J, Ioannidis JP, Balk EM, Milch C, Terrin N, Chew PW, Salem D. Diagnosing acute cardiac ischemia in the emergency department: a systematic review of the accuracy and clinical effect of current technologies. Ann Emerg Med. 2001 May; 37(5):453-60.
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  493. Ioannidis JP, Haidich AB, Lau J. Any casualties in the clash of randomised and observational evidence? BMJ. 2001 Apr 14; 322(7291):879-80.
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  494. Boki KA, Ioannidis JP, Segas JV, Maragkoudakis PV, Petrou D, Adamopoulos GK, Moutsopoulos HM. How significant is sensorineural hearing loss in primary Sjögren's syndrome? An individually matched case-control study. J Rheumatol. 2001 Apr; 28(4):798-801.
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  495. Katritsis DG, Ioannidis JP, Korovesis S, Giazitzoglou E, Parissis J, Kalivas P, Webb-Peploe MM. Comparison of myocardial fractional flow reserve and intravascular ultrasound for the assessment of slotted-tube stents. Catheter Cardiovasc Interv. 2001 Mar; 52(3):322-6; discussion 327.
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  496. Trikalinos TA, Ioannidis JP. Predictive modeling and heterogeneity of baseline risk in meta-analysis of individual patient data. J Clin Epidemiol. 2001 Mar; 54(3):245-52.
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  497. Ioannidis JP, Galanos O, Katritsis D, Connery CP, Drossos GE, Swistel DG, Anagnostopoulos CE. Early mortality and morbidity of bilateral versus single internal thoracic artery revascularization: propensity and risk modeling. J Am Coll Cardiol. 2001 Feb; 37(2):521-8.
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  498. Ioannidis J, Lau J. Evolution of treatment effects over time: empirical insight from recursive cumulative metaanalyses. Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3):831-6.
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  499. Ioannidis JP, Abrams EJ, Ammann A, Bulterys M, Goedert JJ, Gray L, Korber BT, Mayaux MJ, Mofenson LM, Newell ML, Shapiro DE, Teglas JP, Wilfert CM. Perinatal transmission of human immunodeficiency virus type 1 by pregnant women with RNA virus loads <1000 copies/ml. J Infect Dis. 2001 Feb 15; 183(4):539-45.
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  500. Tektonidou MG, Ioannidis JP, Moyssakis I, Boki KA, Vassiliou V, Vlachoyiannopoulos PG, Kyriakidis MK, Moutsopoulos HM. Right ventricular diastolic dysfunction in patients with anticardiolipin antibodies and antiphospholipid syndrome. Ann Rheum Dis. 2001 Jan; 60(1):43-8.
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  501. Efstathiadou Z, Kranas V, Ioannidis JP, Georgiou I, Tsatsoulis A. The Sp1 COLIA1 gene polymorphism, and not vitamin D receptor or estrogen receptor gene polymorphisms, determines bone mineral density in postmenopausal Greek women. Osteoporos Int. 2001; 12(4):326-31.
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  502. Goudas L, Carr DB, Bloch R, Balk E, Ioannidis JP, Terrin N, Gialeli-Goudas M, Chew P, Lau J. Management of cancer pain. Evid Rep Technol Assess (Summ). 2001 Jan; (35):1-5.
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  503. Ioannidis JP, Lau J. Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas. JAMA. 2001 Jan 24-31; 285(4):437-43.
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  504. Karassa FB, Ioannidis JP, Boki KA, Touloumi G, Argyropoulou MI, Strigaris KA, Moutsopoulos HM. Predictors of clinical outcome and radiologic progression in patients with neuropsychiatric manifestations of systemic lupus erythematosus. Am J Med. 2000 Dec 1; 109(8):628-34.
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  505. Giannakakis IA, Ioannidis JP. Arabian nights-1001 tales of how pharmaceutical companies cater to the material needs of doctors: case report. BMJ. 2000 Dec 23-30; 321(7276):1563-4.
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  506. Ioannidis JP, Hesketh PJ, Lau J. Contribution of dexamethasone to control of chemotherapy-induced nausea and vomiting: a meta-analysis of randomized evidence. J Clin Oncol. 2000 Oct 1; 18(19):3409-22.
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  507. Lau J, Ioannidis JP, Wald ER. Diagnosis and treatment of uncomplicated acute sinusitis in children. Evid Rep Technol Assess (Summ). 2000 Oct; (9 Suppl):1-3.
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  508. Spoulou V, Theodoridou M, Papaevangelou VG, Mostrou GI, Ioannidis JP. 23-valent pneumococcal vaccination and HIV. Lancet. 2000 Sep 16; 356(9234):1027-8.
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  509. Lau J, Ioannidis JP, Balk E, Milch C, Chew P, Terrin N, Lang TA, Salem D, Wong JB. Evaluation of technologies for identifying acute cardiac ischemia in emergency departments. Evid Rep Technol Assess (Summ). 2000 Sep; (26):1-4.
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  510. Spoulou V, Victoratos P, Ioannidis JP, Grafakos S. Kinetics of antibody concentration and avidity for the assessment of immune response to pneumococcal vaccine among children with bone marrow transplants. J Infect Dis. 2000 Sep; 182(3):965-9.
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  511. Ioannidis JP, Schmid CH, Lau J. Meta-analysis in hematology and oncology. Hematol Oncol Clin North Am. 2000 Aug; 14(4):973-91.
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  512. Tektonidou MG, Ioannidis JP, Boki KA, Vlachoyiannopoulos PG, Moutsopoulos HM. Prognostic factors and clustering of serious clinical outcomes in antiphospholipid syndrome. QJM. 2000 Aug; 93(8):523-30.
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  513. Ioannidis JP, Havlir DV, Tebas P, Hirsch MS, Collier AC, Richman DD. Dynamics of HIV-1 viral load rebound among patients with previous suppression of viral replication. AIDS. 2000 Jul 28; 14(11):1481-8.
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  514. Tektonidou MG, Petrovas CA, Ioannidis JP, Vlachoyiannopoulos PG, Moutsopoulos HM. Clinical importance of antibodies against platelet activating factor in antiphospholipid syndrome manifestations. Eur J Clin Invest. 2000 Jul; 30(7):646-52.
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  515. Goules A, Masouridi S, Tzioufas AG, Ioannidis JP, Skopouli FN, Moutsopoulos HM. Clinically significant and biopsy-documented renal involvement in primary Sjögren syndrome. Medicine (Baltimore). 2000 Jul; 79(4):241-9.
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  516. Baxter JD, Mayers DL, Wentworth DN, Neaton JD, Hoover ML, Winters MA, Mannheimer SB, Thompson MA, Abrams DI, Brizz BJ, Ioannidis JP, Merigan TC. A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS. AIDS. 2000 Jun 16; 14(9):F83-93.
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  517. O'Brien TR, McDermott DH, Ioannidis JP, Carrington M, Murphy PM, Havlir DV, Richman DD. Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy. AIDS. 2000 May 5; 14(7):821-6.
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  518. Skopouli FN, Dafni U, Ioannidis JP, Moutsopoulos HM. Clinical evolution, and morbidity and mortality of primary Sjögren's syndrome. Semin Arthritis Rheum. 2000 Apr; 29(5):296-304.
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  519. Voulgarelis M, Kokori SI, Ioannidis JP, Tzioufas AG, Kyriaki D, Moutsopoulos HM. Anaemia in systemic lupus erythematosus: aetiological profile and the role of erythropoietin. Ann Rheum Dis. 2000 Mar; 59(3):217-22.
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  520. Rizou C, Ioannidis JP, Panou-Pomonis E, Sakarellos-Daitsiotis M, Sakarellos C, Moutsopoulos HM, Vlachoyiannopoulos PG. B-Cell epitope mapping of DNA topoisomerase I defines epitopes strongly associated with pulmonary fibrosis in systemic sclerosis. Am J Respir Cell Mol Biol. 2000 Mar; 22(3):344-51.
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  521. Karassa FB, Ioannidis JP, Touloumi G, Boki KA, Moutsopoulos HM. Risk factors for central nervous system involvement in systemic lupus erythematosus. QJM. 2000 Mar; 93(3):169-74.
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  522. Kokori SI, Ioannidis JP, Voulgarelis M, Tzioufas AG, Moutsopoulos HM. Autoimmune hemolytic anemia in patients with systemic lupus erythematosus. Am J Med. 2000 Feb 15; 108(3):198-204.
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  523. Mathys JM, Melanson SM, Schiffer-Alberts DJ, Ioannidis JP, Koziel H, Skolnik PR. NF-kappa B modulates TNF-alpha production by alveolar macrophages in asymptomatic HIV-seropositive individuals. J Immunol. 2000 Feb 1; 164(3):1588-94.
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  524. Ioannidis JP, Boki KA, Katsorida ME, Drosos AA, Skopouli FN, Boletis JN, Moutsopoulos HM. Remission, relapse, and re-remission of proliferative lupus nephritis treated with cyclophosphamide. Kidney Int. 2000 Jan; 57(1):258-64.
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  525. Mavragani CP, Ioannidis JP, Tzioufas AG, Hantoumi IE, Moutsopoulos HM. Recurrent pregnancy loss and autoantibody profile in autoimmune diseases. Rheumatology (Oxford). 1999 Dec; 38(12):1228-33.
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  526. Ioannidis JP, Tektonidou MG, Vlachoyiannopoulos PG, Stavropoulos-Giokas C, Spyropoulou-Vlachou M, Reveille JD, Arnett FC, Moutsopoulos HM. HLA associations of anti-beta2 glycoprotein I response in a Greek cohort with antiphospholipid syndrome and meta-analysis of four ethnic groups. Hum Immunol. 1999 Dec; 60(12):1274-80.
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  527. Sipsas NV, Kokori SI, Ioannidis JP, Kyriaki D, Tzioufas AG, Kordossis T. Circulating autoantibodies to erythropoietin are associated with human immunodeficiency virus type 1-related anemia. J Infect Dis. 1999 Dec; 180(6):2044-7.
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  528. Ioannidis JP, Contopoulos-Ioannidis DG. Maternal viral load and the risk of perinatal transmission of HIV-1. N Engl J Med. 1999 Nov 25; 341(22):1698-700.
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  529. Ioannidis JP, Lau J. State of the evidence: current status and prospects of meta-analysis in infectious diseases. Clin Infect Dis. 1999 Nov; 29(5):1178-85.
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  530. Ioannidis JP, Lau J. Pooling research results: benefits and limitations of meta-analysis. Jt Comm J Qual Improv. 1999 Sep; 25(9):462-9.
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  531. Boletis JN, Ioannidis JP, Boki KA, Moutsopoulos HM. Intravenous immunoglobulin compared with cyclophosphamide for proliferative lupus nephritis. Lancet. 1999 Aug 14; 354(9178):569-70.
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  532. Ioannidis JP, Moutsopoulos HM. Sjögren's syndrome: too many associations, too limited evidence. The enigmatic example of CNS involvement. Semin Arthritis Rheum. 1999 Aug; 29(1):1-3.
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  533. Ioannidis JP, Taha TE, Kumwenda N, Broadhead R, Mtimavalye L, Miotti P, Yellin F, Contopoulos-Ioannidis DG, Biggar RJ. Predictors and impact of losses to follow-up in an HIV-1 perinatal transmission cohort in Malawi. Int J Epidemiol. 1999 Aug; 28(4):769-75.
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  534. Ioannidis JP, Dixon DO, McIntosh M, Albert JM, Bozzette SA, Schnittman SM. Relationship between event rates and treatment effects in clinical site differences within multicenter trials: an example from primary Pneumocystis carinii prophylaxis. Control Clin Trials. 1999 Jun; 20(3):253-66.
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  535. Ioannidis JP, Contopoulos-Ioannidis DG, Lau J. Recursive cumulative meta-analysis: a diagnostic for the evolution of total randomized evidence from group and individual patient data. J Clin Epidemiol. 1999 Apr; 52(4):281-91.
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  536. Ioannidis JP, Goedert JJ, McQueen PG, Enger C, Kaslow RA. Comparison of viral load and human leukocyte antigen statistical and neural network predictive models for the rate of HIV-1 disease progression across two cohorts of homosexual men. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Feb 1; 20(2):129-36.
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  537. Ioannidis JP, O'Brien TR, Goedert JJ. Evaluation of guidelines for initiation of highly active antiretroviral therapy in a longitudinal cohort of HIV-infected individuals. AIDS. 1998 Dec 24; 12(18):2417-23.
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  538. Ioannidis JP, Lau J. Heterogeneity of the baseline risk within patient populations of clinical trials: a proposed evaluation algorithm. Am J Epidemiol. 1998 Dec 1; 148(11):1117-26.
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  539. Ioannidis JP, Contopoulos-Ioannidis DG. Reporting of safety data from randomised trials. Lancet. 1998 Nov 28; 352(9142):1752-3.
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  540. Albert JM, Ioannidis JP, Reichelderfer P, Conway B, Coombs RW, Crane L, Demasi R, Dixon DO, Flandre P, Hughes MD, Kalish LA, Larntz K, Lin D, Marschner IC, Muñoz A, Murray J, Neaton J, Pettinelli C, Rida W, Taylor JM, Welles SL. Statistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshop. Stat Med. 1998 Nov 15; 17(21):2435-62.
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  541. Havlir DV, Marschner IC, Hirsch MS, Collier AC, Tebas P, Bassett RL, Ioannidis JP, Holohan MK, Leavitt R, Boone G, Richman DD. Maintenance antiretroviral therapies in HIV infected patients with undetectable plasma HIV RNA after triple-drug therapy. AIDS Clinical Trials Group Study 343 Team. N Engl J Med. 1998 Oct 29; 339(18):1261-8.
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  542. de Ferranti SD, Ioannidis JP, Lau J, Anninger WV, Barza M. Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta-analysis. BMJ. 1998 Sep 5; 317(7159):632-7.
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  543. Ioannidis JP, Lau J. Can quality of clinical trials and meta-analyses be quantified? Lancet. 1998 Aug 22; 352(9128):590-1.
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  544. Ioannidis JP, Collier AC, Cooper DA, Corey L, Fiddian AP, Gazzard BG, Griffiths PD, Contopoulos-Ioannidis DG, Lau J, Pavia AT, Saag MS, Spruance SL, Youle MS. Clinical efficacy of high-dose acyclovir in patients with human immunodeficiency virus infection: a meta-analysis of randomized individual patient data. J Infect Dis. 1998 Aug; 178(2):349-59.
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  545. Ioannidis JP, Lau J. Uncontrolled pearls, controlled evidence, meta-analysis and the individual patient. J Clin Epidemiol. 1998 Aug; 51(8):709-11.
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  546. Wynia MK, Ioannidis JP, Lau J. Analysis of life-long strategies to prevent Pneumocystis carinii pneumonia in patients with variable HIV progression rates. AIDS. 1998 Jul 30; 12(11):1317-25.
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  547. Contopoulos-Ioannidis DG, Ioannidis JP. Maternal cell-free viremia in the natural history of perinatal HIV-1 transmission: a meta-analysis. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Jun 1; 18(2):126-35.
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  548. Ioannidis JP, O'Brien TR, Rosenberg PS, Contopoulos-Ioannidis DG, Goedert JJ. Genetic effects on HIV disease progression. Nat Med. 1998 May; 4(5):536.
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  549. Ioannidis JP, Cappelleri JC, Lau J. Issues in comparisons between meta-analyses and large trials. JAMA. 1998 Apr 8; 279(14):1089-93.
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  550. Ioannidis JP, McQueen PG, Goedert JJ, Kaslow RA. Use of neural networks to model complex immunogenetic associations of disease: human leukocyte antigen impact on the progression of human immunodeficiency virus infection. Am J Epidemiol. 1998 Mar 1; 147(5):464-71.
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  551. Ioannidis JP. Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials. JAMA. 1998 Jan 28; 279(4):281-6.
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  552. Lau J, Ioannidis JP, Schmid CH. Summing up evidence: one answer is not always enough. Lancet. 1998 Jan 10; 351(9096):123-7.
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  553. Ioannidis JP, Cappelleri JC, Lau J. Meta-analyses and large randomized, controlled trials. N Engl J Med. 1998 Jan 1; 338(1):59; author reply 61-2.
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  554. Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med. 1997 Nov 1; 127(9):820-6.
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  555. Ioannidis JP, Cappelleri JC, Sacks HS, Lau J. The relationship between study design, results, and reporting of randomized clinical trials of HIV infection. Control Clin Trials. 1997 Oct; 18(5):431-44.
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  556. Bonis PA, Ioannidis JP, Cappelleri JC, Kaplan MM, Lau J. Correlation of biochemical response to interferon alfa with histological improvement in hepatitis C: a meta-analysis of diagnostic test characteristics. Hepatology. 1997 Oct; 26(4):1035-44.
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  557. Ioannidis JP, Lau J. The impact of high-risk patients on the results of clinical trials. J Clin Epidemiol. 1997 Oct; 50(10):1089-98.
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  558. Ioannidis JP, Bassett R, Hughes MD, Volberding PA, Sacks HS, Lau J. Predictors and impact of patients lost to follow-up in a long-term randomized trial of immediate versus deferred antiretroviral treatment. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Sep 1; 16(1):22-30.
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  559. Ioannidis JP, Cappelleri JC, Schmid CH, Lau J. Impact of epidemic and individual heterogeneity on the population distribution of disease progression rates. An example from patient populations in trials of human immunodeficiency virus infection. Am J Epidemiol. 1996 Dec 1; 144(11):1074-85.
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  560. Cappelleri JC, Ioannidis JP, Schmid CH, de Ferranti SD, Aubert M, Chalmers TC, Lau J. Large trials vs meta-analysis of smaller trials: how do their results compare? JAMA. 1996 Oct 23-30; 276(16):1332-8.
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  561. Ioannidis JP, Lau J. On meta-analyses of meta-analyses. Lancet. 1996 Sep 14; 348(9029):756.
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  562. Ioannidis JP, Cappelleri JC, Lau J. Viral load and response to treatment of HIV. N Engl J Med. 1996 Jun 20; 334(25):1671; author reply 1672-3.
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  563. Ioannidis JP, Cappelleri JC, Lau J, Sacks HS, Skolnik PR. Predictive value of viral load measurements in asymptomatic untreated HIV-1 infection: a mathematical model. AIDS. 1996 Mar; 10(3):255-62.
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  564. Barza M, Ioannidis JP, Cappelleri JC, Lau J. Single or multiple daily doses of aminoglycosides: a meta-analysis. BMJ. 1996 Feb 10; 312(7027):338-45.
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  565. Ioannidis JP, Cappelleri JC, Skolnik PR, Lau J, Sacks HS. A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens. Arch Intern Med. 1996 Jan 22; 156(2):177-88.
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  566. Ioannidis JP, Reichlin S, Skolnik PR. Long-term productive human immunodeficiency virus-1 infection in human infant microglia. Am J Pathol. 1995 Nov; 147(5):1200-6.
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  567. Ioannidis JP, Worthington M, Griffiths JK, Snydman DR. Spectrum and significance of bacteremia due to Moraxella catarrhalis. Clin Infect Dis. 1995 Aug; 21(2):390-7.
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  568. Ioannidis JP, Merino F, Drapkin MS, Lew MA, Cohn LH. Pneumococcal aortitis in the antibiotic era. Arch Intern Med. 1995 Aug 7-21; 155(15):1678-80.
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  569. Ioannidis JP, Skolnik PR, Chalmers TC, Lau J. Human leukocyte antigen associations of epidemic Kaposi's sarcoma. AIDS. 1995 Jun; 9(6):649-51.
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  570. Ioannidis JP, Cappelleri JC, Lau J, Skolnik PR, Melville B, Chalmers TC, Sacks HS. Early or deferred zidovudine therapy in HIV-infected patients without an AIDS-defining illness. Ann Intern Med. 1995 Jun 1; 122(11):856-66.
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  571. Ioannidis JP, Snydman DR, Rohrer RJ, Freeman RB, Haug CE. Aspergillus fumigatus infection of a biloma. Clin Infect Dis. 1995 May; 20(5):1427-8.
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  572. Ioannidis JP, Iacoviello VR, Samore MH. Insulin-dependent diabetes in AIDS. AIDS. 1994 Apr; 8(4):556-7.
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  573. Ioannidis JP, Samarel MD, Lau J, Drapkin MS. Risk of gastrointestinal bleeding from dexamethasone in children with bacterial meningitis. Lancet. 1994 Mar 26; 343(8900):792.
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