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Abraham Morgentaler, M.D.

TitleAssociate Clinical Professor of Surgery
InstitutionBeth Israel Deaconess Medical Center
DepartmentSurgery
AddressOne Brookline Place
Suite #624
Brookline MA 02445
Phone617/277-5000
Fax617/277-5444

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Morgentaler A. Testosterone therapy in men with prostate cancer: scientific and ethical considerations. J Urol. 2013 Jan; 189(1 Suppl):S26-33.
    View in: PubMed
  2. Morgentaler A. Goodbye androgen hypothesis, hello saturation model. Eur Urol. 2012 Nov; 62(5):765-7.
    View in: PubMed
  3. Morgentaler A. Low testosterone levels are related to poor prognosis factors in men with prostate cancer prior to treatment. BJU Int. 2012 Dec; 110(11 Pt B):E547.
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  4. Kacker R, Traish AM, Morgentaler A. Estrogens in men: clinical implications for sexual function and the treatment of testosterone deficiency. J Sex Med. 2012 Jun; 9(6):1681-96.
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  5. McCullough AR, Khera M, Goldstein I, Hellstrom WJ, Morgentaler A, Levine LA. A multi-institutional observational study of testosterone levels after testosterone pellet (Testopel(®)) insertion. J Sex Med. 2012 Feb; 9(2):594-601.
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  6. Di Sante S, Conners WP, Morgentaler A. Influence of baseline serum testosterone on changes in body composition in response to testosterone therapy. J Sex Med. 2012 Feb; 9(2):585-93.
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  7. Conners W, Flinn K, Morgentaler A. Outcomes with the "V" implantation technique vs. standard technique for testosterone pellet therapy. J Sex Med. 2011 Dec; 8(12):3465-70.
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  8. Traish AM, Miner MM, Morgentaler A, Zitzmann M. Testosterone deficiency. Am J Med. 2011 Jul; 124(7):578-87.
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  9. Morgentaler A. Testosterone and prostate cancer: what are the risks for middle-aged men? Urol Clin North Am. 2011 May; 38(2):119-24.
    View in: PubMed
  10. Jannini EA, Gravina GL, Morgentaler A, Mortengaler A, Morales A, Incrocci L, Hellstrom WJ. Is testosterone a friend or a foe of the prostate? J Sex Med. 2011 Apr; 8(4):946-55.
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  11. Morgentaler A. Turning conventional wisdom upside-down: low serum testosterone and high-risk prostate cancer. Cancer. 2011 Sep 1; 117(17):3885-8.
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  12. Morgentaler A. Words of wisdom. Re: Adverse events associated with testosterone administration. Eur Urol. 2011 Mar; 59(3):465.
    View in: PubMed
  13. Morgentaler A, Lipshultz LI, Bennett R, Sweeney M, Avila D, Khera M. Testosterone therapy in men with untreated prostate cancer. J Urol. 2011 Apr; 185(4):1256-60.
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  14. Rosen RC, Araujo AB, Connor MK, Gerstenberger EP, Morgentaler A, Seftel AD, Miner MM, Shabsigh R. The NERI Hypogonadism Screener: psychometric validation in male patients and controls. Clin Endocrinol (Oxf). 2011 Feb; 74(2):248-56.
    View in: PubMed
  15. Morgentaler A, Morales A. Should hypogonadal men with prostate cancer receive testosterone? J Urol. 2010 Oct; 184(4):1257-60.
    View in: PubMed
  16. Buvat J, Maggi M, Gooren L, Guay AT, Kaufman J, Morgentaler A, Schulman C, Tan HM, Torres LO, Yassin A, Zitzmann M. Endocrine aspects of male sexual dysfunctions. J Sex Med. 2010 Apr; 7(4 Pt 2):1627-56.
    View in: PubMed
  17. Morgentaler A, Rhoden EL, Guay A, Traish A. Serum testosterone is associated with aggressive prostate cancer in older men: results from the Baltimore Longitudinal Study of Aging. BJU Int. 2010 Mar; 105(6):884-5; author reply 885-6.
    View in: PubMed
  18. Glina S, Rivero MA, Morales A, Morgentaler A. Studies on prostatic cancer I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate by Charles Huggins and Clarence V. Hodges. J Sex Med. 2010 Feb; 7(2 Pt 1):640-4.
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  19. Rhoden EL, Morgentaler A. Symptomatic response rates to testosterone therapy and the likelihood of completing 12 months of therapy in clinical practice. J Sex Med. 2010 Jan; 7(1 Pt 1):277-83.
    View in: PubMed
  20. Heldwein FL, Rhoden EL, Morgentaler A. Classics of urology: a half century history of the most frequently cited articles (1955-2009). Urology. 2010 Jun; 75(6):1261-8.
    View in: PubMed
  21. Traish AM, Morgentaler A. Epidermal growth factor receptor expression escapes androgen regulation in prostate cancer: a potential molecular switch for tumour growth. Br J Cancer. 2009 Dec 15; 101(12):1949-56.
    View in: PubMed
  22. Moreno SA, Shyam A, Morgentaler A. Comparison of free testosterone results by analog radioimmunoassay and calculated free testosterone in an ambulatory clinical population. J Sex Med. 2010 May; 7(5):1948-53.
    View in: PubMed
  23. Morgentaler A. Rapidly shifting concepts regarding androgens and prostate cancer. ScientificWorldJournal. 2009; 9:685-90.
    View in: PubMed
  24. Rosen RC, Araujo AB, Connor MK, Elstad EA, McGraw SA, Guay AT, Morgentaler A, Miner MM. Assessing symptoms of hypogonadism by self-administered questionnaire: qualitative findings in patients and controls. Aging Male. 2009 Jun-Sep; 12(2-3):77-85.
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  25. Isbarn H, Pinthus JH, Marks LS, Montorsi F, Morales A, Morgentaler A, Schulman C. Testosterone and prostate cancer: revisiting old paradigms. Eur Urol. 2009 Jul; 56(1):48-56.
    View in: PubMed
  26. Moreno SA, Morgentaler A. Testosterone deficiency and Peyronie's disease: pilot data suggesting a significant relationship. J Sex Med. 2009 Jun; 6(6):1729-35.
    View in: PubMed
  27. Morgentaler A. Two years of testosterone therapy associated with decline in prostate-specific antigen in a man with untreated prostate cancer. J Sex Med. 2009 Feb; 6(2):574-7.
    View in: PubMed
  28. Morgentaler A. Testosterone therapy in men with prostate cancer: scientific and ethical considerations. J Urol. 2009 Mar; 181(3):972-9.
    View in: PubMed
  29. Morgentaler A, Schulman C. Testosterone and prostate safety. Front Horm Res. 2009; 37:197-203.
    View in: PubMed
  30. Morgentaler A, Dobs AS, Kaufman JM, Miner MM, Shabsigh R, Swerdloff RS, Wang C. Long acting testosterone undecanoate therapy in men with hypogonadism: results of a pharmacokinetic clinical study. J Urol. 2008 Dec; 180(6):2307-13.
    View in: PubMed
  31. Dobs AS, Morgentaler A. Does testosterone therapy increase the risk of prostate cancer? Endocr Pract. 2008 Oct; 14(7):904-11.
    View in: PubMed
  32. Morgentaler A, Traish AM. Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growth. Eur Urol. 2009 Feb; 55(2):310-20.
    View in: PubMed
  33. Morgentaler A. Guilt by association: a historical perspective on Huggins, testosterone therapy, and prostate cancer. J Sex Med. 2008 Aug; 5(8):1834-40.
    View in: PubMed
  34. Morgentaler A. Re: effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial. Eur Urol. 2008 May; 53(5):1084.
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  35. Morgentaler A. Response to: Efficacy of changing testosterone gel preparations (Androgel or Testim) among suboptimally responsive hypogonadal men. Int J Impot Res. 2008 May-Jun; 20(3):331; author reply 332.
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  36. Lazarou S, Morgentaler A. The effect of aging on spermatogenesis and pregnancy outcomes. Urol Clin North Am. 2008 May; 35(2):331-9, xi.
    View in: PubMed
  37. Rhoden EL, Riedner CE, Morgentaler A. The ratio of serum testosterone-to-prostate specific antigen predicts prostate cancer in hypogonadal men. J Urol. 2008 May; 179(5):1741-4.
    View in: PubMed
  38. Morgentaler A. Testosterone replacement therapy and prostate cancer. Urol Clin North Am. 2007 Nov; 34(4):555-63, vii.
    View in: PubMed
  39. Crawford ED, Barqawi AB, O'Donnell C, Morgentaler A. The association of time of day and serum testosterone concentration in a large screening population. BJU Int. 2007 Sep; 100(3):509-13.
    View in: PubMed
  40. Mulhall JP, Morgentaler A. Penile rehabilitation should become the norm for radical prostatectomy patients. J Sex Med. 2007 May; 4(3):538-43.
    View in: PubMed
  41. Morgentaler A. Re: The interpretation of serum prostate specific antigen in men receiving 5alpha-reductase inhibitors: a review and clinical recommendations. J Urol. 2007 May; 177(5):1954.
    View in: PubMed
  42. Morgentaler A. Testosterone deficiency and prostate cancer: emerging recognition of an important and troubling relationship. Eur Urol. 2007 Sep; 52(3):623-5.
    View in: PubMed
  43. Morgentaler A. New concepts regarding the relationship of testosterone and prostate cancer. Future Oncol. 2007 Apr; 3(2):123-6.
    View in: PubMed
  44. Morgentaler A. Re: Masashi Yano, Takashi Imamoto, Hiroyoshi Suzuki et Al. The clinical potential of pretreatment serum testosterone level to improve the efficiency of prostate cancer screening. Eur urol 2007;51:375-80. Eur Urol. 2007 Jul; 52(1):292; author reply 293-4.
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  45. Morgentaler A. Cultural biases and scientific squabbles: the challenges to acceptance of testosterone therapy as a mainstream medical treatment. Aging Male. 2007 Mar; 10(1):1-2.
    View in: PubMed
  46. Morgentaler A. Commentary: Guideline for male testosterone therapy: a clinician's perspective. J Clin Endocrinol Metab. 2007 Feb; 92(2):416-7.
    View in: PubMed
  47. Lux M, Reyes-Vallejo L, Morgentaler A, Levine LA. Outcomes and satisfaction rates for the redesigned 2-piece penile prosthesis. J Urol. 2007 Jan; 177(1):262-6.
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  48. Morgentaler A, Rhoden EL. Prevalence of prostate cancer among hypogonadal men with prostate-specific antigen levels of 4.0 ng/mL or less. Urology. 2006 Dec; 68(6):1263-7.
    View in: PubMed
  49. Reyes-Vallejo L, Lazarou S, Morgentaler A. Subjective sexual response to testosterone replacement therapy based on initial serum levels of total testosterone. J Sex Med. 2007 Nov; 4(6):1757-62.
    View in: PubMed
  50. Lazarou S, Reyes-Vallejo L, Morgentaler A. Wide variability in laboratory reference values for serum testosterone. J Sex Med. 2006 Nov; 3(6):1085-9.
    View in: PubMed
  51. Morgentaler A. Testosterone therapy for men at risk for or with history of prostate cancer. Curr Treat Options Oncol. 2006 Sep; 7(5):363-9.
    View in: PubMed
  52. Morgentaler A. Testosterone and prostate cancer: an historical perspective on a modern myth. Eur Urol. 2006 Nov; 50(5):935-9.
    View in: PubMed
  53. Lazarou S, Reyes-Vallejo L, Morgentaler A. Phleboliths in varicoceles presenting as spermatic cord mass. Fertil Steril. 2006 Jul; 86(1):219.e21-2.
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  54. Morgentaler A, Barada J, Niederberger C, Donatucci C, Garcia CS, Natanegara F, Ahuja S, Wong DG. Efficacy and safety of tadalafil across ethnic groups and various risk factors in men with erectile dysfunction: Use of a novel noninferiority study design. J Sex Med. 2006 May; 3(3):492-503.
    View in: PubMed
  55. Morgentaler A, Rhoden EL, Barqawi AB, Crawford ED. Re: Prostate cancer in men using testosterone supplementation. F. D. Gaylis, D. W. Lin, J. M. Ignatoff, C. L. Amling, R. F. Tutrone and D. J. Cosgrove. J Urol. 2006 Apr; 175(4):1572; author reply 1573-4.
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  56. Reyes-Vallejo L, Lazarou S, Morgentaler A. Y chromosome microdeletions and male infertility: who should be tested and why? BJU Int. 2006 Mar; 97(3):441-3.
    View in: PubMed
  57. Rhoden EL, Morgentaler A. Influence of demographic factors and biochemical characteristics on the prostate-specific antigen (PSA) response to testosterone replacement therapy. Int J Impot Res. 2006 Mar-Apr; 18(2):201-5.
    View in: PubMed
  58. Morgentaler A. Testosterone replacement therapy and prostate risks: where's the beef? Can J Urol. 2006 Feb; 13 Suppl 1:40-3.
    View in: PubMed
  59. Lazarou S, Reyes-Vallejo L, Morgentaler A. Technical advances in penile prostheses. J Long Term Eff Med Implants. 2006; 16(3):235-47.
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  60. Lazarou S, Morgentaler A. Hypogonadism in the man with erectile dysfunction: what to look for and when to treat. Curr Urol Rep. 2005 Nov; 6(6):476-81.
    View in: PubMed
  61. Ramsawh HJ, Morgentaler A, Covino N, Barlow DH, DeWolf WC. Quality of life following simultaneous placement of penile prosthesis with radical prostatectomy. J Urol. 2005 Oct; 174(4 Pt 1):1395-8.
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  62. Cady B, Barker F, Easson A, Aboulafia AJ, Ferson PF, Miner T, Morgentaler A. Part 3: surgical palliation of advanced illness: what's new, what's helpful. J Am Coll Surg. 2005 Mar; 200(3):457-66.
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  63. Cady B, Miner T, Morgentaler A. Part 2: Surgical palliation of advanced illness: what's new, what's helpful. J Am Coll Surg. 2005 Feb; 200(2):281-90.
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  64. Morgentaler A. A 66-year-old man with sexual dysfunction. JAMA. 2004 Jun 23; 291(24):2994-3003.
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  65. Rhoden EL, Morgentaler A. Treatment of testosterone-induced gynecomastia with the aromatase inhibitor, anastrozole. Int J Impot Res. 2004 Feb; 16(1):95-7.
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  66. Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. N Engl J Med. 2004 Jan 29; 350(5):482-92.
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  67. Rhoden EL, Morgentaler A. Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia. J Urol. 2003 Dec; 170(6 Pt 1):2348-51.
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  68. Rhoden EL, Gobbi D, Rhoden CR, Menti E, Roehe AN, Hartmann A, Morgentaler A. Effects of chronic administration of dehydroepiandrosterone on serum testosterone levels and prostatic tissue in rats. J Urol. 2003 Nov; 170(5):2101-3.
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  69. Rhoden EL, Estrada C, Levine L, Morgentaler A. The value of pituitary magnetic resonance imaging in men with hypogonadism. J Urol. 2003 Sep; 170(3):795-8.
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  70. Rhoden EL, Morgentaler A. Erectile dysfunction. J Long Term Eff Med Implants. 2003; 13(6):519-28.
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  71. Yin Y, Stahl BC, DeWolf WC, Morgentaler A. P53 and Fas are sequential mechanisms of testicular germ cell apoptosis. J Androl. 2002 Jan-Feb; 23(1):64-70.
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  72. Levine LA, Estrada CR, Morgentaler A. Mechanical reliability and safety of, and patient satisfaction with the Ambicor inflatable penile prosthesis: results of a 2 center study. J Urol. 2001 Sep; 166(3):932-7.
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  73. Hoffman MA, DeWolf WC, Morgentaler A. Is low serum free testosterone a marker for high grade prostate cancer? J Urol. 2000 Mar; 163(3):824-7.
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  74. Morgentaler A. Male impotence. Lancet. 1999 Nov 13; 354(9191):1713-8.
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  75. Morgentaler A, Stahl BC, Yin Y. Testis and temperature: an historical, clinical, and research perspective. J Androl. 1999 Mar-Apr; 20(2):189-95.
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  76. Yin Y, Stahl BC, DeWolf WC, Morgentaler A. p53-mediated germ cell quality control in spermatogenesis. Dev Biol. 1998 Dec 1; 204(1):165-71.
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  77. Yin Y, Stahl BC, DeWolf WC, Morgentaler A. Heat-induced testicular apoptosis occurs independently of hormonal depletion. Apoptosis. 1998 Sep; 3(4):281-7.
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  78. Morgentaler A. Motile organisms in the epididymis? Hum Reprod. 1998 Aug; 13(8):2335.
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  79. Khoudary KP, Morgentaler A. Partial duplication of the vas deferens. J Urol. 1998 Mar; 159(3):988-9.
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  80. Yin Y, DeWolf WC, Morgentaler A. Experimental cryptorchidism induces testicular germ cell apoptosis by p53-dependent and -independent pathways in mice. Biol Reprod. 1998 Feb; 58(2):492-6.
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  81. Morgentaler A. Causality and association--more than just different shades of gray. Fertil Steril. 1997 Oct; 68(4):745.
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  82. Khoudary KP, DeWolf WC, Bruning CO, Morgentaler A. Immediate sexual rehabilitation by simultaneous placement of penile prosthesis in patients undergoing radical prostatectomy: initial results in 50 patients. Urology. 1997 Sep; 50(3):395-9.
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  83. Yin Y, DeWolf WC, Morgentaler A. p53 is associated with the nuclear envelope in mouse testis. Biochem Biophys Res Commun. 1997 Jun 27; 235(3):689-94.
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  84. Socher SA, Yin Y, Dewolf WC, Morgentaler A. Temperature-mediated germ cell loss in the testis is associated with altered expression of the cell-cycle regulator p53. J Urol. 1997 May; 157(5):1986-9.
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  85. Yin Y, Hawkins KL, DeWolf WC, Morgentaler A. Heat stress causes testicular germ cell apoptosis in adult mice. J Androl. 1997 Mar-Apr; 18(2):159-65.
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  86. Vohra S, Morgentaler A. Congenital anomalies of the vas deferens, epididymis, and seminal vesicles. Urology. 1997 Mar; 49(3):313-21.
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  87. Khoudary KP, Morgentaler A. Design considerations in penile prostheses: the American Medical Systems product line. J Long Term Eff Med Implants. 1997; 7(1):55-64.
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  88. Morgentaler A, Bruning CO, DeWolf WC. Occult prostate cancer in men with low serum testosterone levels. JAMA. 1996 Dec 18; 276(23):1904-6.
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  89. Socher SA, Dewolf WC, Morgentaler A. Ureteral pseudodiverticulosis: the case for the retrograde urogram. Urology. 1996 Jun; 47(6):924-7.
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  90. Maranchie J, Morgentaler A. Management of impending sterility. Lancet. 1996 May 11; 347(9011):1344.
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  91. Dahl DM, Klein D, Morgentaler A. Penile mass caused by the newly described organism Mycobacterium celatum. Urology. 1996 Feb; 47(2):266-8.
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  92. Morgentaler A, Fung MY, Harris DH, Powers RD, Alper MM. Sperm morphology and in vitro fertilization outcome: a direct comparison of World Health Organization and strict criteria methodologies. Fertil Steril. 1995 Dec; 64(6):1177-82.
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  93. Comiter CV, Bruning CO, Morgentaler A. Detached ciliary tufts in the epididymis: a lesson in applied anatomy. Urology. 1995 Nov; 46(5):740-2.
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  94. Bruning CO, Morgentaler A. Re: Unilateral unitary inflatable penile prosthesis to correct impaired tumescence and severe penile deformity resulting from traumatic rupture of 1 corpus cavernosum. J Urol. 1995 Sep; 154(3):1145.
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  95. Brown LF, Yeo KT, Berse B, Morgentaler A, Dvorak HF, Rosen S. Vascular permeability factor (vascular endothelial growth factor) is strongly expressed in the normal male genital tract and is present in substantial quantities in semen. J Urol. 1995 Aug; 154(2 Pt 1):576-9.
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  96. Rubenstein SC, Green LS, Schopperle WM, DeWolf WC, Morgentaler A. Temperature-dependent expression of a 95 kD protein in rat testis. Andrologia. 1995 Mar-Apr; 27(2):107-13.
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  97. Watson DL, Morgentaler A. Spontaneous corporeal herniation of the penis: a new abnormality of the tunica albuginea? J Urol. 1995 Mar; 153(3 Pt 1):737-40.
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  98. Bruning CO, Breslin DS, Morgentaler A, Staskin DR. Experience with the penile prosthesis and artificial urinary sphincter. J Long Term Eff Med Implants. 1995; 5(1):27-45.
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  99. Ho GT, Gardner H, Mostofi K, DeWolf WC, Loughlin KR, Morgentaler A. The effect of testicular nongerm cell tumors on local spermatogenesis. Fertil Steril. 1994 Jul; 62(1):162-6.
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  100. Morgentaler A. Hyponatremic encephalopathy after endometrial ablation. JAMA. 1994 Feb 2; 271(5):344; author reply 345.
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  101. Morgentaler A, DeWolf WC. A self-expanding prostatic stent for bladder outlet obstruction in high risk patients. J Urol. 1993 Nov; 150(5 Pt 2):1636-40.
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  102. Morgentaler A, DeWolf WC. Vasectomy and increased risk of prostate cancer. JAMA. 1993 Aug 11; 270(6):705-6; author reply 708.
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  103. Ho GT, Gardner H, DeWolf WC, Loughlin KR, Morgentaler A. Influence of testicular carcinoma on ipsilateral spermatogenesis. J Urol. 1992 Sep; 148(3):821-5.
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  104. Kritsas JJ, Schopperle WM, DeWolf WC, Morgentaler A. Rapid high resolution two-dimensional electrophoresis of human sperm proteins. Electrophoresis. 1992 Jul; 13(7):445-9.
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  105. Morgentaler A. Current diagnosis and management of impotence. Compr Ther. 1991 Jul; 17(7):25-30.
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  106. Morgentaler A, Schopperle WM, Crocker RH, DeWolf WC. Protein differences between normal and oligospermic human sperm demonstrated by two-dimensional gel electrophoresis. Fertil Steril. 1990 Nov; 54(5):902-5.
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  107. Morgentaler A, Koufman CN. Treatment of an impacted fecalith with electrohydraulic lithotripsy. N Engl J Med. 1990 Mar 22; 322(12):855-6.
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  108. Morgentaler A, Bridge SS, Dretler SP. Management of the impacted ureteral calculus. J Urol. 1990 Feb; 143(2):263-6.
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  109. Morgentaler A, Belville JS, Tumeh SS, Richie JP, Loughlin KR. Rational approach to evaluation and management of spontaneous perirenal hemorrhage. Surg Gynecol Obstet. 1990 Feb; 170(2):121-5.
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  110. Belville JS, Morgentaler A, Loughlin KR, Tumeh SS. Spontaneous perinephric and subcapsular renal hemorrhage: evaluation with CT, US, and angiography. Radiology. 1989 Sep; 172(3):733-8.
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  111. Morgentaler A, Garnick MB, Richie JP. Metastatic testicular teratoma invading the inferior vena cava. J Urol. 1988 Jul; 140(1):149-50.
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  112. Morrell JI, Crews D, Ballin A, Morgentaler A, Pfaff DW. 3H-estradiol, 3H-testosterone and 3H-dihydrotestosterone localization in the brain of the lizard Anolis carolinensis: an autoradiographic study. J Comp Neurol. 1979 Nov 15; 188(2):201-23.
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  113. Crews D, Morgentaler A. Effects of intracranial implantation of oestradiol and dihydrotestosterone on the sexual behaviour of the lizard Anolis carolinensis. J Endocrinol. 1979 Sep; 82(3):373-81.
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