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Seok-Hyun Yun, PH.D.

TitleAssociate Professor of Dermatology
InstitutionMassachusetts General Hospital
DepartmentDermatology
AddressPartners Research Building
Wellman Center for Photomedicine, UP-5
65 Landsdowne St
Cambridge MA 02139
Phone617/768-8704
Fax617/768-8710

 Overview 
 overview
Dr. Andy Yun is a faculty member of the Wellman Center for Photomedicine at MGH.
URL: http://www2.massgeneral.org/wellman/

Yun Lab Homepage: http://www.intelon.org


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Scarcelli G, Kling S, Quijano E, Pineda R, Marcos S, Yun SH. Brillouin microscopy of collagen crosslinking: noncontact depth-dependent analysis of corneal elastic modulus. Invest Ophthalmol Vis Sci. 2013; 54(2):1418-25.
    View in: PubMed
  2. Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH. Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts. Circ Res. 2013 Mar 15; 112(6):891-9.
    View in: PubMed
  3. Kim JK, Vinarsky V, Wain J, Zhao R, Jung K, Choi J, Lam A, Pardo-Saganta A, Breton S, Rajagopal J, Yun SH. In Vivo Imaging of Tracheal Epithelial Cells in Mice during Airway Regeneration. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):864-8.
    View in: PubMed
  4. Lee SJ, Lee EJ, Kim SK, Jeong P, Cho YH, Yun SJ, Kim S, Kim GY, Choi YH, Cha EJ, Kim WJ, Moon SK. Identification of pro-inflammatory cytokines associated with muscle invasive bladder cancer; the roles of IL-5, IL-20, and IL-28A. PLoS One. 2012; 7(9):e40267.
    View in: PubMed
  5. Chang EW, Kobler JB, Yun SH. Subnanometer optical coherence tomographic vibrography. Opt Lett. 2012 Sep 1; 37(17):3678-80.
    View in: PubMed
  6. Goh EJ, Kim KS, Kim YR, Jung HS, Beack S, Kong WH, Scarcelli G, Yun SH, Hahn SK. Bioimaging of hyaluronic acid derivatives using nanosized carbon dots. Biomacromolecules. 2012 Aug 13; 13(8):2554-61.
    View in: PubMed
  7. Kim JK, Lee WM, Kim P, Choi M, Jung K, Kim S, Yun SH. Fabrication and operation of GRIN probes for in vivo fluorescence cellular imaging of internal organs in small animals. Nat Protoc. 2012 Aug; 7(8):1456-69.
    View in: PubMed
  8. Kim DG, Choi JW, Lee JY, Kim H, Oh YS, Lee JW, Tak YK, Song JM, Razin E, Yun SH, Kim S. Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration. FASEB J. 2012 Oct; 26(10):4142-59.
    View in: PubMed
  9. Kim KS, Kim S, Beack S, Yang JA, Yun SH, Hahn SK. In vivo real-time confocal microscopy for target-specific delivery of hyaluronic acid-quantum dot conjugates. Nanomedicine. 2012 Oct; 8(7):1070-3.
    View in: PubMed
  10. Choi JW, Lee JW, Kim JK, Jeon HK, Choi JJ, Kim DG, Kim BG, Nam DH, Kim HJ, Yun SH, Kim S. Splicing variant of AIMP2 as an effective target against chemoresistant ovarian cancer. J Mol Cell Biol. 2012 Jun; 4(3):164-73.
    View in: PubMed
  11. Scarcelli G, Yun SH. In vivo Brillouin optical microscopy of the human eye. Opt Express. 2012 Apr 9; 20(8):9197-202.
    View in: PubMed
  12. Scarcelli G, Pineda R, Yun SH. Brillouin optical microscopy for corneal biomechanics. Invest Ophthalmol Vis Sci. 2012 Jan; 53(1):185-90.
    View in: PubMed
  13. Li X, Utomo A, Cullere X, Choi MM, Milner DA, Venkatesh D, Yun SH, Mayadas TN. The ß-glucan receptor Dectin-1 activates the integrin Mac-1 in neutrophils via Vav protein signaling to promote Candida albicans clearance. Cell Host Microbe. 2011 Dec 15; 10(6):603-15.
    View in: PubMed
  14. Lee WM, Yun SH. Adaptive aberration correction of GRIN lenses for confocal endomicroscopy. Opt Lett. 2011 Dec 1; 36(23):4608-10.
    View in: PubMed
  15. van de Ven AL, Kim P, Haley O, Fakhoury JR, Adriani G, Schmulen J, Moloney P, Hussain F, Ferrari M, Liu X, Yun SH, Decuzzi P. Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution. J Control Release. 2012 Feb 28; 158(1):148-55.
    View in: PubMed
  16. Kim SK, Yun SJ, Kim J, Lee OJ, Bae SC, Kim WJ. Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model. PLoS One. 2011; 6(10):e26131.
    View in: PubMed
  17. Scarcelli G, Kim P, Yun SH. In vivo measurement of age-related stiffening in the crystalline lens by Brillouin optical microscopy. Biophys J. 2011 Sep 21; 101(6):1539-45.
    View in: PubMed
  18. Kuehne AJ, Gather MC, Eydelnant IA, Yun SH, Weitz DA, Wheeler AR. A switchable digital microfluidic droplet dye-laser. Lab Chip. 2011 Nov 7; 11(21):3716-9.
    View in: PubMed
  19. Gather MC, Yun SH. Lasing from Escherichia coli bacteria genetically programmed to express green fluorescent protein. Opt Lett. 2011 Aug 15; 36(16):3299-301.
    View in: PubMed
  20. Chang EW, Kobler JB, Yun SH. Triggered optical coherence tomography for capturing rapid periodic motion. Sci Rep. 2011; 1:48.
    View in: PubMed
  21. Zhi L, Kim P, Thompson BD, Pitsillides C, Bankovich AJ, Yun SH, Lin CP, Cyster JG, Wu MX. FTY720 blocks egress of T cells in part by abrogation of their adhesion on the lymph node sinus. J Immunol. 2011 Sep 1; 187(5):2244-51.
    View in: PubMed
  22. Benichou G, Yamada Y, Yun SH, Lin C, Fray M, Tocco G. Immune recognition and rejection of allogeneic skin grafts. Immunotherapy. 2011 Jun; 3(6):757-70.
    View in: PubMed
  23. Scarcelli G, Yun SH. Multistage VIPA etalons for high-extinction parallel Brillouin spectroscopy. Opt Express. 2011 May 23; 19(11):10913-22.
    View in: PubMed
  24. Alonzo CA, Yun SH. Harmonic mode locking in a sliding-frequency fiber laser. Opt Lett. 2011 May 1; 36(9):1590-2.
    View in: PubMed
  25. Kim WJ, Kim SK, Jeong P, Yun SJ, Cho IC, Kim IY, Moon SK, Um HD, Choi YH. A four-gene signature predicts disease progression in muscle invasive bladder cancer. Mol Med. 2011 May-Jun; 17(5-6):478-85.
    View in: PubMed
  26. Kim WT, Yun SJ, Park C, Kim IY, Moon SK, Kwon TG, Choi YH, Kim WJ. Identification of C16orf74 as a marker of progression in primary non-muscle invasive bladder cancer. PLoS One. 2010; 5(12):e15260.
    View in: PubMed
  27. Chen X, Kim P, Farinelli B, Doukas A, Yun SH, Gelfand JA, Anderson RR, Wu MX. A novel laser vaccine adjuvant increases the motility of antigen presenting cells. PLoS One. 2010; 5(10):e13776.
    View in: PubMed
  28. Ghosh SK, Kim P, Zhang XA, Yun SH, Moore A, Lippard SJ, Medarova Z. A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing. Cancer Res. 2010 Aug 1; 70(15):6119-27.
    View in: PubMed
  29. Kobler JB, Chang EW, Zeitels SM, Yun SH. Dynamic imaging of vocal fold oscillation with four-dimensional optical coherence tomography. Laryngoscope. 2010 Jul; 120(7):1354-62.
    View in: PubMed
  30. Fan Z, Spencer JA, Lu Y, Pitsillides CM, Singh G, Kim P, Yun SH, Toxavidis V, Strom TB, Lin CP, Koulmanda M. In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response. Nat Med. 2010 Jun; 16(6):718-22.
    View in: PubMed
  31. Koo JH, Lee I, Yun SK, Kim HU, Park BH, Park JW. Saponified evening primrose oil reduces melanogenesis in B16 melanoma cells and reduces UV-induced skin pigmentation in humans. Lipids. 2010 May; 45(5):401-7.
    View in: PubMed
  32. Kim P, Chung E, Yamashita H, Hung KE, Mizoguchi A, Kucherlapati R, Fukumura D, Jain RK, Yun SH. In vivo wide-area cellular imaging by side-view endomicroscopy. Nat Methods. 2010 Apr; 7(4):303-5.
    View in: PubMed
  33. Kang JW, Kim P, Alonzo CA, Park H, Yun SH. Two-photon microscopy by wavelength-swept pulses delivered through single-mode fiber. Opt Lett. 2010 Jan 15; 35(2):181-3.
    View in: PubMed
  34. Kim WJ, Kim EJ, Kim SK, Kim YJ, Ha YS, Jeong P, Kim MJ, Yun SJ, Lee KM, Moon SK, Lee SC, Cha EJ, Bae SC. Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancer. Mol Cancer. 2010; 9:3.
    View in: PubMed
  35. Itaka K, Osada K, Morii K, Kim P, Yun SH, Kataoka K. Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle. J Control Release. 2010 Apr 2; 143(1):112-9.
    View in: PubMed
  36. Zhong W, Celli JP, Rizvi I, Mai Z, Spring BQ, Yun SH, Hasan T. In vivo high-resolution fluorescence microendoscopy for ovarian cancer detection and treatment monitoring. Br J Cancer. 2009 Dec 15; 101(12):2015-22.
    View in: PubMed
  37. Desjardins AE, Vakoc BJ, Suter MJ, Yun SH, Tearney GJ, Bouma BE. Real-time FPGA processing for high-speed optical frequency domain imaging. IEEE Trans Med Imaging. 2009 Sep; 28(9):1468-72.
    View in: PubMed
  38. Bouma BE, Yun SH, Vakoc BJ, Suter MJ, Tearney GJ. Fourier-domain optical coherence tomography: recent advances toward clinical utility. Curr Opin Biotechnol. 2009 Feb; 20(1):111-8.
    View in: PubMed
  39. Scarcelli G, Kim P, Yun SH. Cross-axis cascading of spectral dispersion. Opt Lett. 2008 Dec 15; 33(24):2979-81.
    View in: PubMed
  40. Sharma U, Chang EW, Yun SH. Long-wavelength optical coherence tomography at 1.7 microm for enhanced imaging depth. Opt Express. 2008 Nov 24; 16(24):19712-23.
    View in: PubMed
  41. Scarcelli G, Yun SH. Entangled-photon coincidence fluorescence imaging. Opt Express. 2008 Sep 29; 16(20):16189-94.
    View in: PubMed
  42. Oh WY, Vakoc BJ, Yun SH, Tearney GJ, Bouma BE. Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation. Opt Lett. 2008 Jun 15; 33(12):1330-2.
    View in: PubMed
  43. Oh WY, Yun SH, Vakoc BJ, Shishkov M, Desjardins AE, Park BH, de Boer JF, Tearney GJ, Bouma BE. High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing. Opt Express. 2008 Jan 21; 16(2):1096-103.
    View in: PubMed
  44. Kim P, Puoris'haag M, Côté D, Lin CP, Yun SH. In vivo confocal and multiphoton microendoscopy. J Biomed Opt. 2008 Jan-Feb; 13(1):010501.
    View in: PubMed
  45. Yelin R, Yelin D, Oh WY, Yun SH, Boudoux C, Vakoc BJ, Bouma BE, Tearney GJ. Multimodality optical imaging of embryonic heart microstructure. J Biomed Opt. 2007 Nov-Dec; 12(6):064021.
    View in: PubMed
  46. Vakoc BJ, Shishko M, Yun SH, Oh WY, Suter MJ, Desjardins AE, Evans JA, Nishioka NS, Tearney GJ, Bouma BE. Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video). Gastrointest Endosc. 2007 May; 65(6):898-905.
    View in: PubMed
  47. Yun SH, Tearney GJ, Vakoc BJ, Shishkov M, Oh WY, Desjardins AE, Suter MJ, Chan RC, Evans JA, Jang IK, Nishioka NS, de Boer JF, Bouma BE. Comprehensive volumetric optical microscopy in vivo. Nat Med. 2006 Dec; 12(12):1429-33.
    View in: PubMed
  48. Bilenca A, Yun SH, Tearney GJ, Bouma BE. Numerical study of wavelength-swept semiconductor ring lasers: the role of refractive-index nonlinearities in semiconductor optical amplifiers and implications for biomedical imaging applications. Opt Lett. 2006 Mar 15; 31(6):760-2.
    View in: PubMed
  49. Vakoc BJ, Yun SH, Tearney GJ, Bouma BE. Elimination of depth degeneracy in optical frequency-domain imaging through polarization-based optical demodulation. Opt Lett. 2006 Feb 1; 31(3):362-4.
    View in: PubMed
  50. Cense B, Chen TC, Nassif N, Pierce MC, Yun SH, Park BH, Bouma BE, Tearney GJ, de Boer JF. Ultra-high speed and ultra-high resolution spectral-domain optical coherence tomography and optical Doppler tomography in ophthalmology. Bull Soc Belge Ophtalmol. 2006; (302):123-32.
    View in: PubMed
  51. Yun SH. Optical coherence tomography using rapidly swept lasers. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:125-8.
    View in: PubMed
  52. Oh WY, Yun SH, Tearney GJ, Bouma BE. 115 kHz tuning repetition rate ultrahigh-speed wavelength-swept semiconductor laser. Opt Lett. 2005 Dec 1; 30(23):3159-61.
    View in: PubMed
  53. Chen TC, Cense B, Pierce MC, Nassif N, Park BH, Yun SH, White BR, Bouma BE, Tearney GJ, de Boer JF. Spectral domain optical coherence tomography: ultra-high speed, ultra-high resolution ophthalmic imaging. Arch Ophthalmol. 2005 Dec; 123(12):1715-20.
    View in: PubMed
  54. Yun SH. Mode locking of a wavelength-swept laser. Opt Lett. 2005 Oct 1; 30(19):2660-2.
    View in: PubMed
  55. Yelin D, Yun SH, Bouma BE, Tearney GJ. Three-dimensional imaging using spectral encoding heterodyne interferometry. Opt Lett. 2005 Jul 15; 30(14):1794-6.
    View in: PubMed
  56. Park B, Pierce MC, Cense B, Yun SH, Mujat M, Tearney G, Bouma B, de Boer J. Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm. Opt Express. 2005 May 30; 13(11):3931-44.
    View in: PubMed
  57. Yelin D, Bouma BE, Yun SH, Tearney GJ. Double-clad fiber for endoscopy. Opt Lett. 2004 Oct 15; 29(20):2408-10.
    View in: PubMed
  58. Cense B, Nassif N, Chen T, Pierce M, Yun SH, Park B, Bouma B, Tearney G, de Boer J. Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography. Opt Express. 2004 May 31; 12(11):2435-47.
    View in: PubMed
  59. Nassif N, Cense B, Park BH, Yun SH, Chen TC, Bouma BE, Tearney GJ, de Boer JF. In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography. Opt Lett. 2004 Mar 1; 29(5):480-2.
    View in: PubMed
  60. Yun SH, Boudoux C, Tearney GJ, Bouma BE. High-speed wavelength-swept semiconductor laser with a polygon-scanner-based wavelength filter. Opt Lett. 2003 Oct 15; 28(20):1981-3.
    View in: PubMed
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