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Institution

Vijay Yajnik, M.D.

TitleAssistant Professor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Gastrointestinal Unit - GRJ 815
55 Fruit St
Boston MA 02114
Phone617/726-1306
Fax617/726-3673

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Desai A, Zator ZA, de Silva P, Nguyen DD, Korzenik J, Yajnik V, Ananthakrishnan AN. Older Age Is Associated with Higher Rate of Discontinuation of Anti-TNF Therapy in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2013 Feb; 19(2):309-15.
    View in: PubMed
  2. de Silva PS, Nguyen DD, Sauk J, Korzenik J, Yajnik V, Ananthakrishnan AN. Long-term outcome of a third anti-TNF monoclonal antibody after the failure of two prior anti-TNFs in inflammatory bowel disease. Aliment Pharmacol Ther. 2012 Sep; 36(5):459-66.
    View in: PubMed
  3. Axelrad JE, Fowler SA, Friedman S, Ananthakrishnan AN, Yajnik V. Effects of cancer treatment on inflammatory bowel disease remission and reactivation. Clin Gastroenterol Hepatol. 2012 Sep; 10(9):1021-7.e1.
    View in: PubMed
  4. Lee J, Hirsh AS, Wittner BS, Maeder ML, Singavarapu R, Lang M, Janarthanan S, McDermott U, Yajnik V, Ramaswamy S, Joung JK, Sgroi DC. Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library. PLoS One. 2011; 6(7):e21112.
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  5. Zhou L, Opalinska J, Sohal D, Yu Y, Mo Y, Bhagat T, Abdel-Wahab O, Fazzari M, Figueroa M, Alencar C, Zhang J, Kambhampati S, Parmar S, Nischal S, Hueck C, Suzuki M, Freidman E, Pellagatti A, Boultwood J, Steidl U, Sauthararajah Y, Yajnik V, McMahon C, Gore SD, Platanias LC, Levine R, Melnick A, Wickrema A, Greally JM, Verma A. Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q. J Biol Chem. 2011 Jul 15; 286(28):25211-23.
    View in: PubMed
  6. Subramanian S, Yajnik V, Sands BE, Cullen G, Korzenik JR. Characterization of patients with infliximab-induced lupus erythematosus and outcomes after retreatment with a second anti-TNF agent. Inflamm Bowel Dis. 2011 Jan; 17(1):99-104.
    View in: PubMed
  7. Cullen G, Sands BE, Yajnik V. Babesiosis in a patient on infliximab for Crohn's disease. Inflamm Bowel Dis. 2010 Aug; 16(8):1269-70.
    View in: PubMed
  8. Lyubimova A, Garber JJ, Upadhyay G, Sharov A, Anastasoaie F, Yajnik V, Cotsarelis G, Dotto GP, Botchkarev V, Snapper SB. Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice. J Clin Invest. 2010 Feb; 120(2):446-56.
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  9. Kawada K, Upadhyay G, Ferandon S, Janarthanan S, Hall M, Vilardaga JP, Yajnik V. Cell migration is regulated by platelet-derived growth factor receptor endocytosis. Mol Cell Biol. 2009 Aug; 29(16):4508-18.
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  10. Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V. Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. Oncogene. 2008 Oct 2; 27(44):5845-55.
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  11. Kankel MW, Hurlbut GD, Upadhyay G, Yajnik V, Yedvobnick B, Artavanis-Tsakonas S. Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector. Genetics. 2007 Dec; 177(4):2493-505.
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  12. Yan D, Li F, Hall ML, Sage C, Hu WH, Giallourakis C, Upadhyay G, Ouyang XM, Du LL, Bethea JR, Chen ZY, Yajnik V, Liu XZ. An isoform of GTPase regulator DOCK4 localizes to the stereocilia in the inner ear and binds to harmonin (USH1C). J Mol Biol. 2006 Mar 31; 357(3):755-64.
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  13. Lu M, Kinchen JM, Rossman KL, Grimsley C, Hall M, Sondek J, Hengartner MO, Yajnik V, Ravichandran KS. A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs. Curr Biol. 2005 Feb 22; 15(4):371-7.
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  14. Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature. 2003 Oct 23; 425(6960):851-6.
    View in: PubMed
  15. Reynolds PA, Smolen GA, Palmer RE, Sgroi D, Yajnik V, Gerald WL, Haber DA. Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein. Genes Dev. 2003 Sep 1; 17(17):2094-107.
    View in: PubMed
  16. Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA. DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell. 2003 Mar 7; 112(5):673-84.
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  17. Karnik ND, Oza YK, Sane SP, Kaushik R, Bhatt AD, Chawla KP, Vaidya AB, Yajnik VH, Khokhani RC. An open clinical trial of benazepril--a new ACE inhibitor in mild-moderate hypertension. J Assoc Physicians India. 1998 Mar; 46(3):283-5.
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  18. Isakoff SJ, Yu YP, Su YC, Blaikie P, Yajnik V, Rose E, Weidner KM, Sachs M, Margolis B, Skolnik EY. Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo. J Biol Chem. 1996 Feb 23; 271(8):3959-62.
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  19. Yajnik VH, Vatsaraj DJ, Acharya HK, Yajnik NV. Clinical trial of nicardipine in treatment of mild to moderate hypertension. J Assoc Physicians India. 1995 Jun; 43(6):401-3.
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  20. Yajnik VH, Vatsaraj DJ, Acharya HK, Yajnik NV. Evaluation of amlodipine in mild to moderate hypertension--a clinical report. J Assoc Physicians India. 1995 Jan; 43(1):34-5.
    View in: PubMed
  21. Yajnik VH, Vatsraj DJ, Acharya HK, Yajnik NV, Vyas NR, Vakil HB. Ramipril vs captopril in mild to moderate hypertension. J Assoc Physicians India. 1994 Feb; 42(2):120-3.
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  22. Yajnik VH, Vatsraj DJ, Vora LS, Patel SI, Kapur A. Effects of purified insulins on insulin requirement and metabolic control. J Assoc Physicians India. 1990 Apr; 38(4):281-2.
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  23. Yajnik VH, Vatsraj DJ, Vora LS, Oke VG, Jha RJ, Patel K, Navani SR, Raghu CN. Comparative evaluation of captopril and metoprolol as first choice anti-hypertensive in Indian patients. Br J Clin Pract. 1988 Oct; 42(10):407-11.
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  24. Yajnik VH, Nandi JS, Karvadia SV. Penbutolol in hypertension--single daily doses versus divided dosage schedule. J Assoc Physicians India. 1982 Feb; 30(2):85-8.
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  25. Yajnik VH, Patel SC. Prazosin in hypertension: crossover comparison with methyldopa and long-term efficacy. J Assoc Physicians India. 1981 Jul; 29(7):531-6.
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  26. Yajnik VH, Patel SC. Double blind evaluation of indoramin and methyldopa in thiazide treated hypertensive patients. Indian Heart J. 1978 Jan-Feb; 30(1):51-6.
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  27. Yajnik VH, Doshi HV, Vassa NT, Kshatriya PK, Vaidya MH, Patel SH. Occipito-atlanto-axial joint in rheumatoid arthritis. J Indian Med Assoc. 1977 Aug 1; 69(3):45-9.
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  28. Yajnik VH, Doshi HV, Patel SC, Doshi KJ. Combined treatment with triamterene and benzthiazide in cases of hypertension. J Assoc Physicians India. 1977 Jan; 25(1):31-6.
    View in: PubMed
  29. Yajnik VH, Nandi JS, Patel SC, Doshi HV, Patel SH. Penbutolol in hypertension: a pilot study with single daily doses. J Int Med Res. 1977; 5(4):236-42.
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  30. Yajnik VH, Kshatriya PK, Vaidya MH, Vassa NT. Marfan's syndrome, ventricular septal defect and basilar impression in one patient. J Indian Med Assoc. 1975 May 1; 64(9):242-4.
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  31. Vassa NT, Doshi HV, Yajnik VH, Shah SS, Joshi KR, Patel SH. Comparative clinical trial of diazepam with other conventional drugs in tetanus. Postgrad Med J. 1974 Dec; 50(590):755-8.
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  32. Yajnik VH, Vassa NT, Agrawal G, Kapadia BK, Shah PR, Patel SC, Aghera VH. Auriculotemporal syndrome: a case report. Indian J Med Sci. 1974 Feb; 28(2):89-93.
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  33. Vassa NT, Yajnik VH, Shah SS, Doshi HV, Kothari UR, Joshi KR. Myocarditis in rabies--clinical and electrocardiographic study of 16 cases. J Assoc Physicians India. 1974 Jan; 22(1):7-11.
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  34. Vassa NT, Solanki SV, Yajnik VH. Myelitis due to enteric fever. Trop Geogr Med. 1973 Sep; 25(3):245-8.
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  35. Yajnik VH, Solanki SV. Combined treatment with furosemide and reserpine in cases of hypertension. Indian J Med Sci. 1973 Aug; 27(8):611-7.
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  36. Solanki SV, Yajnik VH, Shah SS, Shah DP. Longterm clinical study with glibenclamide. J Assoc Physicians India. 1973 Jan; 21(1):1-9.
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  37. Yajnik VH, Solanki SV. Iatrogenic neurological disorders. Indian J Med Sci. 1972 Jul; 26(7):419-27.
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  38. Yajnik VH, Hinduja AK, Vyas DK, Morjaria MM. Myoclonus epilepsy associated with basilar impression. J Assoc Physicians India. 1972 Apr; 20(4):325-8.
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  39. Patel MB, Yajnik VH. Craniovertebral anomalies. A clinical and radiological study of 32 cases. Indian J Med Sci. 1972 Feb; 26(2):90-8.
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  40. Solanki SV, Yajnik VH. Ortner's syndrome. Indian Heart J. 1972 Jan; 24(1):43-6.
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  41. Solanki SV, Yajnik VH, Sutaria VM, Kabrawala VN, Dave BT. Glibenclamide (HB 419) in the management of diabetes mellitus. Indian J Med Sci. 1971 Sep; 25(9):579-89.
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  42. Patel MB, Yajnik VH. Spastic paraplegia--an aetiological and clinical study. J Indian Med Assoc. 1971 Apr 16; 56(8):225-9.
    View in: PubMed
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