 George Tofaris, M.D.,Ph.D.
| Title | Research Fellow in Neurology (EXT) |
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| Institution | Brigham and Women's Hospital |
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| Department | Neurology |
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| Address | Brigham and Womens Hospital
Neurology
75 Francis St
Boston MA 02115
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Tofaris GK. Lysosome-dependent pathways as a unifying theme in Parkinson's disease. Mov Disord. 2012 Sep 15; 27(11):1364-9.
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Tofaris GK, Irani SR, Cheeran BJ, Baker IW, Cader ZM, Vincent A. Immunotherapy-responsive chorea as the presenting feature of LGI1-antibody encephalitis. Neurology. 2012 Jul 10; 79(2):195-6.
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Tofaris GK, Kim HT, Hourez R, Jung JW, Kim KP, Goldberg AL. Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):17004-9.
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Garcia-Reitböck P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, Ghetti B, Della Corte L, Spano P, Tofaris GK, Goedert M, Spillantini MG. SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. Brain. 2010 Jul; 133(Pt 7):2032-44.
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Tofaris GK, Farmer SF. Focal Paraneoplastic Syndrome associated with small cell carcinoma of the lung. J Neurol. 2008 Jan; 255(1):123-4.
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Tofaris GK, Spillantini MG. Physiological and pathological properties of alpha-synuclein. Cell Mol Life Sci. 2007 Sep; 64(17):2194-201.
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Tofaris GK, Revesz T, Jacques TS, Papacostas S, Chataway J. Adult-onset neurodegeneration with brain iron accumulation and cortical alpha-synuclein and tau pathology: a distinct clinicopathological entity. Arch Neurol. 2007 Feb; 64(2):280-2.
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Michell AW, Tofaris GK, Gossage H, Tyers P, Spillantini MG, Barker RA. The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease. Cell Transplant. 2007; 16(5):461-74.
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Tofaris GK, Garcia Reitböck P, Humby T, Lambourne SL, O'Connell M, Ghetti B, Gossage H, Emson PC, Wilkinson LS, Goedert M, Spillantini MG. Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. J Neurosci. 2006 Apr 12; 26(15):3942-50.
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Tofaris GK, Wistow T. An unusual cause of rigors and microscopic haematuria. Lancet. 2006 Feb 18; 367(9510):622.
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Tofaris GK, Spillantini MG. Alpha-synuclein dysfunction in Lewy body diseases. Mov Disord. 2005 Aug; 20 Suppl 12:S37-44.
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Tofaris GK, Razzaq A, Ghetti B, Lilley KS, Spillantini MG. Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function. J Biol Chem. 2003 Nov 7; 278(45):44405-11.
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Tofaris GK, Patterson PH, Jessen KR, Mirsky R. Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF. J Neurosci. 2002 Aug 1; 22(15):6696-703.
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Tofaris GK, Layfield R, Spillantini MG. alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome. FEBS Lett. 2001 Nov 30; 509(1):22-6.
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