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Fred L. Hacker, PH.D.

TitleAssistant Professor of Radiation Oncology
InstitutionBrigham and Women's Hospital
DepartmentRadiation Oncology
AddressBrigham and Women's Hospital
Radiation Oncology
75 Francis St
Boston MA 02115
Phone617/732-7577
Fax617/732-7347

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. James SS, Mishra P, Hacker F, Berbeco RI, Lewis JH. Quantifying ITV instabilities arising from 4DCT: a simulation study using patient data. Phys Med Biol. 2012 Mar 7; 57(5):L1-7.
    View in: PubMed
  2. Kelly PJ, Mannarino E, Lewis JH, Baldini EH, Hacker FL. Total dural irradiation: RapidArc versus static-field IMRT: a case study. Med Dosim. 2012; 37(2):175-81.
    View in: PubMed
  3. Kelly PJ, Lin YB, Yu AY, Ropper AE, Nguyen PL, Marcus KJ, Hacker FL, Weiss SE. Linear accelerator-based stereotactic radiosurgery for brainstem metastases: the Dana-Farber/Brigham and Women's Cancer Center experience. J Neurooncol. 2011 Sep; 104(2):553-7.
    View in: PubMed
  4. Kelly PJ, Lin YB, Yu AY, Alexander BM, Hacker F, Marcus KJ, Weiss SE. Stereotactic irradiation of the postoperative resection cavity for brain metastasis: a frameless linear accelerator-based case series and review of the technique. Int J Radiat Oncol Biol Phys. 2012 Jan 1; 82(1):95-101.
    View in: PubMed
  5. Ramakrishna N, Rosca F, Friesen S, Tezcanli E, Zygmanszki P, Hacker F. A clinical comparison of patient setup and intra-fraction motion using frame-based radiosurgery versus a frameless image-guided radiosurgery system for intracranial lesions. Radiother Oncol. 2010 Apr; 95(1):109-15.
    View in: PubMed
  6. Park SJ, Ionascu D, Hacker F, Mamon H, Berbeco R. Automatic marker detection and 3D position reconstruction using cine EPID images for SBRT verification. Med Phys. 2009 Oct; 36(10):4536-46.
    View in: PubMed
  7. Lyatskaya Y, Kadam D, Levitsky G, Hacker F, Chin L. Evaluation of a new IR-guided system for mechanical QA of linear accelerators. Med Phys. 2008 Nov; 35(11):4816-23.
    View in: PubMed
  8. Berbeco RI, Hacker F, Zatwarnicki C, Park SJ, Ionascu D, O'Farrell D, Mamon HJ. A novel method for estimating SBRT delivered dose with beam's-eye-view images. Med Phys. 2008 Jul; 35(7):3225-31.
    View in: PubMed
  9. Allen AM, Schofield D, Hacker F, Court LE, Czerminska M. Restricted field IMRT dramatically enhances IMRT planning for mesothelioma. Int J Radiat Oncol Biol Phys. 2007 Dec 1; 69(5):1587-92.
    View in: PubMed
  10. Berbeco RI, Hacker F, Ionascu D, Mamon HJ. Clinical feasibility of using an EPID in CINE mode for image-guided verification of stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys. 2007 Sep 1; 69(1):258-66.
    View in: PubMed
  11. Park S, Ionascu D, Hacker F, Berbeco R. Automatic Target Position Verification with 3-D Reconstruction of Implanted Markers Using EPID Images. Medical Physics. 2007; 34(6):2334.
  12. Kadam D, Levitsky G, Hacker F, Chin L, Lyatskaya Y. A Novel Infrared Camera System for Mechanical QA of Radiation Treatment Accelerators. Medical Physics. 2007; 34(6):2533.
  13. Czerminska MA, Schofield D, Hacker FL, Baldini EH, Allen A. Restricted Field IMRT Dramatically Enhances IMRT Planning for Mesothelioma Patients. International Journal of Radiation Oncology Biology Physics. 2006; 66(3, Supplement 1):S680.
  14. Rosca F, Lorenz F, Hacker FL, Chin LM, Ramakrishna N, Zygmanski P. An MLC-based linac QA procedure for the characterization of radiation isocenter and room lasers' position. Med Phys. 2006 Jun; 33(6):1780-7.
    View in: PubMed
  15. Hacker F, Rosca F, Friesen S, Zygmanski P, Ramakrishna N. Accuracy assessment of a non-invasive image guided system for intra-cranial linac based radiosurgery. Medical Physics. 2006; 33:2066.
  16. Berbeco R, Ionascu D, Hacker F, Lobo J, Mamon H. A novel method for image-guided verification of SBRT with an EPID in cine mode. Medical Physics. 2006; 33:2021.
  17. Schofield D, Court L, Allen A, Hacker F, Czerminska M. Experimental evaluation of the accuracy of contralateral lung dose calculations for IMRT plans. Medical Physics. 2006; 33:2286.
  18. RI Berbeco, F Hacker, D Ionascu, HJ Mamon. A novel method for image-guided verification of hypofractionated extra-cranial radiation therapy with an EPID in cine mode. Poster Presentation, 9th International Workshop on Electronic Portal Imaging. 2006.
  19. Zygmanski P, Hacker F, Friesen S, Rodenbush R, Lu HM, Chin L. Maximum MLC opening effect in dynamic delivery of IMRT: leaf-positional analysis. J Appl Clin Med Phys. 2005; 6(2):33-43.
    View in: PubMed
  20. Rosca F, Zygmanski P, Lorenz F, Hacker F, Chin L, Friesen S, Petsuksiri J, Shanmugham L, Ramakrishna N. A new linac QA procedure for the characterization of gantry radiation isocenter. Medical Physics. 2005; 32:1990.
  21. Hacker F. Compared with inverse-planning, forward planning is preferred for IMRT stereotactic radiosurgery. For the proposition. Med Phys. 2003 May; 30(5):731-2.
    View in: PubMed
  22. Zygmanski P, Hacker F, Lu H, Chin L. A retrospective analysis of dynamic MLC controller log-file (DynLog TM) data for Novalis system and its implication on the IMRT fluence distribution. Medical Physics. 2003; 30:1361.
  23. Hacker F, Ramakrishna N. Evaluation of prescription normalization to minimize integral normal tissue dose for radiosurgery with the Novalis shaped beam radiosurgery system. Presented at the 6th Congress of the International Stereotactic Radiosurgery Society (ISRS). 2003.
  24. Hacker F, Zygmanski P, Ramakrishna N. A comparison of forward planned IMRT to inverse planned IMRT for stereotactic radiotherapy. Medical Physics. 2002; 29:1367.
  25. Hacker FL, Bellerive MR, Kooy HM, Dutton SC, Shafman TD. Conformal static field stereotactic radiotherapy for larger intracranial lesions. Radiosurgery 1999. 2000; 3:91-99.
  26. Bues M, Kooy HM, Hacker FL, Tarbell NJ, Chapman P, Loeffler JS. MicroIMRT for intracranial tumors - a case study. Radiosurgery 1999. 2000; 3:64-72.
  27. Kooy HM, Hacker FL, Bellerive MR. Jaw and circular collimator. 1999.
  28. Bues M, Kooy HM, Hacker FL, Tarbell NJ, Chapman P, Loeffler JS. Micro-IMRT for stereotactic radiotherapy of intracranial tumors. International Journal of Radiation Oncology Biology Physics. 1999; 45(3 Supplement 1):319.
  29. Hacker F, Bellerive M, Kooy H. Dosimetric comparison of a fast TMR dose algorithm to a full clarkson integration algorithm. Medical Physics. 1998; 25(7):A187.
  30. Hacker FL, Bellerive MR, Kooy HM, Leber ZH, Shrieve DC, Tarbell NJ, Loeffler JS. Study and implementation of a simple beam shaping system for stereotactic radiotherapy. Radiosurgery 1997. 1998; 2:228-235.
  31. Hacker FL, Kooy HM, Bellerive MR, Killoran JH, Leber ZH, Shrieve DC, Tarbell NJ, Loeffler JS. Beam shaping for conformal fractionated stereotactic radiotherapy: a modeling study. Int J Radiat Oncol Biol Phys. 1997 Jul 15; 38(5):1113-21.
    View in: PubMed
  32. Hacker FL, Bellerive MR, Kooy HM. Implementation of a conformal stereotactic radiosurgery/radiotherapy system. Medical Physics. 1997; 24:971.
  33. Kooy HM, Cosman EE, Harlan RB, Ledoux RJ, Bellerive MR, Hacker FL, Killoran JH, Mannarino EG, Tarbell NJ, Alexander E III, Shrieve DC, Loeffler JS. A dynamic collimator system for conformal stereotactic radiosurgery and radiotherapy. Radiosurgery 1995. 1996; 1:276.
  34. Killoran JH, Kooy HM, Bellerive MR, Hacker FL, Mannarino EG, Shiu AS, Shriever DC, Tarbell NT, Loeffler JS. Treatment planning support for dynamic linac stereotactic delivery. Radiosurgery 1995. 1996; 1:288.
  35. Hacker FL, Kooy HM, Leber ZH, Killoran JH, Bellerive MR, Tarbell NJ, Shrieve DC, Loeffler JS. Conformal stereotactic arc therapy using multiple independent jaws. Medical Physics. 1996; 23:1052.
  36. Antes KJ, Shiu AS, Kooy HM, Hacker FL, Tung SS, Wong J, Ewton JR. Verification of conformal therapy delivered using a miniature multileaf collimator (MMLC) for stereotactic radiosurgery and radiotherapy. Presented at the annual meeting of the AAPM. 1995.
  37. Shiu AS, Kooy HM, Hacker FL, Tung SS, Wong J, Antes K, Sawaya R, Maor MH. Evaluation of a computer-controlled miniature multileaf collimator (MMLC) for stereotactic radiosurgery and radiotherapy. Presented at the 2nd Congress of the International Stereotactic Radiosurgery Society (ISRS). 1995.
  38. HACKER FL. Mode-locking in a grating coupled oscillator. 1994.
  39. Killoran JH, Hacker FL, Walsh JE. A millimeter-wavelength radiation source using a dual-grating resonator. IEEE Transactions on Plasma Science. 1994; 22:530-535.
  40. Adler R, Richter-Sand R, Hacker F, Walsh J, Arman M. Recent multiwave cherenkov generator experiments. Intense Microwave Pulses II. 1994.
  41. Hacker F, Walsh J, Adler R, Richter-Sand R. Multiwave cherenkov generator experiments. Intense Microwave Pulses SPIE 1872. 1993; SPIE 1872:311-314.
  42. Fisch EE, Hacker FL, Walsh JE. Operation of the saphire cerenkov laser. Sixteenth International Conference on Infrared and Millimeter Waves SPIE 1576. 1991; 1576:480-481.
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