 Harvey Cantor, M.D.
| Title | Baruj Benacerraf Professor of Microbiology and Immunobiology |
|---|
| Institution | Dana-Farber Cancer Institute |
|---|
| Department | Microbiology and Immunobiology |
|---|
| Address | Dana-Farber Cancer Institute
Cancer Immunology & AIDS, Smith 722
450 Brookline Avenue
Boston MA 02215
|
|---|
| Phone | 617/632-3348 |
|---|
| Fax | 617/632-4630 |
|---|
|
|
|
 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Faculty can login to make corrections and additions.
-
Leavenworth JW, Tang X, Kim HJ, Wang X, Cantor H. Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells. J Clin Invest. 2013 Mar 1; 123(3):1382-9.
-
Yao Y, Han W, Liang J, Ji J, Wang J, Cantor H, Lu L. Glatiramer acetate ameliorates inflammatory bowel disease in mice through the induction of Qa-1-restricted CD8(+) regulatory cells. Eur J Immunol. 2013 Jan; 43(1):125-36.
-
Kim HJ, Cantor H. Regulation of self-tolerance by Qa-1-restricted CD8(+) regulatory T cells. Semin Immunol. 2011 Dec; 23(6):446-52.
-
Wang X, Werneck MB, Wilson BG, Kim HJ, Kluk MJ, Thom CS, Wischhusen JW, Evans JA, Jesneck JL, Nguyen P, Sansam CG, Cantor H, Roberts CW. TCR-dependent transformation of mature memory phenotype T cells in mice. J Clin Invest. 2011 Oct; 121(10):3834-45.
-
Leavenworth JW, Wang X, Wenander CS, Spee P, Cantor H. Mobilization of natural killer cells inhibits development of collagen-induced arthritis. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14584-9.
-
Varthaman A, Clement M, Khallou-Laschet J, Fornasa G, Gaston AT, Dussiot M, Caligiuri G, Cantor H, Kaveri S, Nicoletti A. Physiological induction of regulatory Qa-1-restricted CD8+ T cells triggered by endogenous CD4+ T cell responses. PLoS One. 2011; 6(6):e21628.
-
Kim HJ, Wang X, Radfar S, Sproule TJ, Roopenian DC, Cantor H. CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice. Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5):2010-5.
-
Kim HJ, Verbinnen B, Tang X, Lu L, Cantor H. Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance. Nature. 2010 Sep 16; 467(7313):328-32.
-
Mitsdoerffer M, Lee Y, Jäger A, Kim HJ, Korn T, Kolls JK, Cantor H, Bettelli E, Kuchroo VK. Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14292-7.
-
Varthaman A, Khallou-Laschet J, Clement M, Fornasa G, Kim HJ, Gaston AT, Dussiot M, Caligiuri G, Herbelin A, Kaveri S, Cantor H, Nicoletti A. Control of T cell reactivation by regulatory Qa-1-restricted CD8+ T cells. J Immunol. 2010 Jun 15; 184(12):6585-91.
-
Alvarez Arias DA, McCarty N, Lu L, Maldonado RA, Shinohara ML, Cantor H. Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6):2556-61.
-
Leavenworth JW, Schellack C, Kim HJ, Lu L, Spee P, Cantor H. Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2. Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6):2562-7.
-
Egli D, Sandler VM, Shinohara ML, Cantor H, Eggan K. Reprogramming after chromosome transfer into mouse blastomeres. Curr Biol. 2009 Aug 25; 19(16):1403-9.
-
Cantor H, Shinohara ML. Regulation of T-helper-cell lineage development by osteopontin: the inside story. Nat Rev Immunol. 2009 Feb; 9(2):137-41.
-
Cornejo MG, Kharas MG, Werneck MB, Le Bras S, Moore SA, Ball B, Beylot-Barry M, Rodig SJ, Aster JC, Lee BH, Cantor H, Merlio JP, Gilliland DG, Mercher T. Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models. Blood. 2009 Mar 19; 113(12):2746-54.
-
Lu L, Kim HJ, Werneck MB, Cantor H. Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease. Proc Natl Acad Sci U S A. 2008 Dec 9; 105(49):19420-5.
-
Lu L, Cantor H. Generation and regulation of CD8(+) regulatory T cells. Cell Mol Immunol. 2008 Dec; 5(6):401-6.
-
Shinohara ML, Kim JH, Garcia VA, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008 Jul 18; 29(1):68-78.
-
Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol. 2008 Jun 15; 180(12):8004-10.
-
Shinohara ML, Kim HJ, Kim JH, Garcia VA, Cantor H. Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. Proc Natl Acad Sci U S A. 2008 May 20; 105(20):7235-9.
-
Zhou J, Matsuoka M, Cantor H, Homer R, Enelow RI. Cutting edge: engagement of NKG2A on CD8+ effector T cells limits immunopathology in influenza pneumonia. J Immunol. 2008 Jan 1; 180(1):25-9.
-
Colmenero P, Zhang AL, Qian T, Lu L, Cantor H, Söderström K, Engleman EG. Qa-1(b)-dependent modulation of dendritic cell and NK cell cross-talk in vivo. J Immunol. 2007 Oct 1; 179(7):4608-15.
-
Lu L, Ikizawa K, Hu D, Werneck MB, Wucherpfennig KW, Cantor H. Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity. 2007 May; 26(5):593-604.
-
Shinohara ML, Cantor H. The bridge between dendritic cells and asthma. Nat Med. 2007 May; 13(5):536-8.
-
Lu L, Werneck MB, Cantor H. The immunoregulatory effects of Qa-1. Immunol Rev. 2006 Aug; 212:51-9.
-
Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol. 2006 May; 7(5):498-506.
-
Shinohara ML, Jansson M, Hwang ES, Werneck MB, Glimcher LH, Cantor H. T-bet-dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci U S A. 2005 Nov 22; 102(47):17101-6.
-
Paust S, Cantor H. Regulatory T cells and autoimmune disease. Immunol Rev. 2005 Apr; 204:195-207.
-
Bach JF, Bendelac A, Brenner MB, Cantor H, De Libero G, Kronenberg M, Lanier LL, Raulet DH, Shlomchik MJ, von Herrath MG. The role of innate immunity in autoimmunity. J Exp Med. 2004 Dec 20; 200(12):1527-31.
-
McCarty N, Paust S, Ikizawa K, Dan I, Li X, Cantor H. Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes. Nat Immunol. 2005 Jan; 6(1):65-72.
-
Sarantopoulos S, Lu L, Cantor H. Qa-1 restriction of CD8+ suppressor T cells. J Clin Invest. 2004 Nov; 114(9):1218-21.
-
Jacobs JP, Pettit AR, Shinohara ML, Jansson M, Cantor H, Gravallese EM, Mathis D, Benoist C. Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. Arthritis Rheum. 2004 Aug; 50(8):2685-94.
-
Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28):10398-403.
-
McCarty N, Shinohara ML, Lu L, Cantor H. Detailed analysis of gene expression during development of T cell lineages in the thymus. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9339-44.
-
Hu D, Ikizawa K, Lu L, Sanchirico ME, Shinohara ML, Cantor H. Analysis of regulatory CD8 T cells in Qa-1-deficient mice. Nat Immunol. 2004 May; 5(5):516-23.
-
Panoutsakopoulou V, Huster KM, McCarty N, Feinberg E, Wang R, Wucherpfennig KW, Cantor H. Suppression of autoimmune disease after vaccination with autoreactive T cells that express Qa-1 peptide complexes. J Clin Invest. 2004 Apr; 113(8):1218-24.
-
Cantor H. Reviving suppression? Nat Immunol. 2004 Apr; 5(4):347-9.
-
Kissler S, Lu L, Cantor H. Thymic selection can compensate for mutations affecting T cell activation and generate a normal T cell repertoire in mutant mice. Proc Natl Acad Sci U S A. 2004 Jan 6; 101(1):210-4.
-
Weber GF, Zawaideh S, Hikita S, Kumar VA, Cantor H, Ashkar S. Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation. J Leukoc Biol. 2002 Oct; 72(4):752-61.
-
Yang XF, Ye Q, Press B, Han RZ, Bassing CH, Sleckman BP, Alt FW, Cantor H. Analysis of the complex genomic structure of Bcl-x and its relationship to Bcl-x(gamma) expression after CD28-dependent costimulation. Mol Immunol. 2002 Sep; 39(1-2):45-55.
-
Ye Q, Press B, Kissler S, Yang XF, Lu L, Bassing CH, Sleckman BP, Jansson M, Panoutsakopoulou V, Trimble LA, Alt FW, Cantor H. T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice. J Exp Med. 2002 Jul 1; 196(1):87-95.
-
Trimble LA, Prince KA, Pestano GA, Daley J, Cantor H. Fas-dependent elimination of nonselected CD8 cells and lpr disease. J Immunol. 2002 May 15; 168(10):4960-7.
-
Huster KM, Panoutsakopoulou V, Prince K, Sanchirico ME, Cantor H. T cell-dependent and -independent pathways to tissue destruction following herpes simplex virus-1 infection. Eur J Immunol. 2002 May; 32(5):1414-9.
-
Weber GF, Bronson RT, Ilagan J, Cantor H, Schmits R, Mak TW. Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res. 2002 Apr 15; 62(8):2281-6.
-
Jansson M, Panoutsakopoulou V, Baker J, Klein L, Cantor H. Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice. J Immunol. 2002 Mar 1; 168(5):2096-9.
-
Weber GF, Cantor H. Differential roles of osteopontin/Eta-1 in early and late lpr disease. Clin Exp Immunol. 2001 Dec; 126(3):578-83.
-
Nguyen QD, Uy HS, Merchant A, Medina CA, Baltatzis S, Zhao T, Zhao ZS, Cantor H, Foster CS. Effect of Fas and Fas ligand deficiency in resistance of C57BL/6 mice to HSV-1 keratitis and chorioretinitis. Invest Ophthalmol Vis Sci. 2001 Oct; 42(11):2505-9.
-
Panoutsakopoulou V, Sanchirico ME, Huster KM, Jansson M, Granucci F, Shim DJ, Wucherpfennig KW, Cantor H. Analysis of the relationship between viral infection and autoimmune disease. Immunity. 2001 Jul; 15(1):137-47.
-
Adler B, Ashkar S, Cantor H, Weber GF. Costimulation by extracellular matrix proteins determines the response to TCR ligation. Cell Immunol. 2001 May 25; 210(1):30-40.
-
Panoutsakopoulou V, Cantor H. On the relationship between viral infection and autoimmunity. J Autoimmun. 2001 May; 16(3):341-5.
-
Suri-Payer E, Cantor H. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J Autoimmun. 2001 Mar; 16(2):115-23.
-
Wang R, Ramaswamy S, Hu D, Cantor H. Definition of a novel binding site on CD8 cells for a conserved region of the MHC class Ib molecule Qa-1 that regulates IFN-gamma expression. Eur J Immunol. 2001 Jan; 31(1):87-93.
-
Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, Rittling SR, Denhardt DT, Glimcher MJ, Cantor H. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science. 2000 Feb 4; 287(5454):860-4.
-
Cantor H. T-cell receptor crossreactivity and autoimmune disease. Adv Immunol. 2000; 75:209-33.
-
Pestano GA, Zhou Y, Trimble LA, Daley J, Weber GF, Cantor H. Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death. Science. 1999 May 14; 284(5417):1187-91.
-
Adler B, Weber GF, Cantor H. Activation of T cells by superantigen: cytokine production but not apoptosis depends on MEK-1 activity. Eur J Immunol. 1998 Nov; 28(11):3749-54.
-
Zhao ZS, Granucci F, Yeh L, Schaffer PA, Cantor H. Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection. Science. 1998 Feb 27; 279(5355):1344-7.
-
Noble A, Zhao ZS, Cantor H. Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses. J Immunol. 1998 Jan 15; 160(2):566-71.
-
Noble A, Pestano GA, Cantor H. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. J Immunol. 1998 Jan 15; 160(2):559-65.
-
Yang XF, Weber GF, Cantor H. A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells. Immunity. 1997 Nov; 7(5):629-39.
-
Weber GF, Mirza NM, Yunis EJ, Dubey D, Cantor H. Localization and treatment of an oxidation-sensitive defect within the TCR-coupled signalling pathway that is associated with normal and premature immunologic aging. Growth Dev Aging. 1997 Fall-Winter; 61(3-4):191-207.
-
Weber GF, Daley J, Kraeft SK, Chen LB, Cantor H. Measurement of apoptosis in heterogenous cell populations. Cytometry. 1997 Feb 1; 27(2):136-44.
-
Weber GF, Ashkar S, Cantor H. Interaction between CD44 and osteopontin as a potential basis for metastasis formation. Proc Assoc Am Physicians. 1997 Jan; 109(1):1-9.
-
Weber GF, Cantor H. The immunology of Eta-1/osteopontin. Cytokine Growth Factor Rev. 1996 Oct; 7(3):241-8.
-
Weber GF, Ashkar S, Glimcher MJ, Cantor H. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science. 1996 Jan 26; 271(5248):509-12.
-
Avery AC, Zhao ZS, Rodriguez A, Bikoff EK, Soheilian M, Foster CS, Cantor H. Resistance to herpes stromal keratitis conferred by an IgG2a-derived peptide. Nature. 1995 Aug 3; 376(6539):431-4.
-
Cantor H. The role of Eta-1/osteopontin in the pathogenesis of immunological disorders. Ann N Y Acad Sci. 1995 Apr 21; 760:143-50.
-
Weber GF, Abromson-Leeman S, Cantor H. A signaling pathway coupled to T cell receptor ligation by MMTV superantigen leading to transient activation and programmed cell death. Immunity. 1995 Apr; 2(4):363-72.
-
Avery AC, Markowitz JS, Grusby MJ, Glimcher LH, Cantor H. Activation of T cells by superantigen in class II-negative mice. J Immunol. 1994 Dec 1; 153(11):4853-61.
-
Weber GF, Cantor H. Phosphatidylinositol synthesis is a proximal event in intracellular signaling coupled to T cell receptor ligation. Differential induction by conventional antigen and retroviral superantigen. J Immunol. 1994 May 1; 152(9):4433-43.
-
Crump AL, Grusby MJ, Glimcher LH, Cantor H. Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10739-43.
-
Weber GF, Cantor H. HIV glycoprotein as a superantigen. A mechanism of autoimmunity and implications for a vaccination strategy. Med Hypotheses. 1993 Sep; 41(3):247-50.
-
Patarca R, Fletcher MA, Cantor H. Structural features of two T-cell-specific genes that suggest a potential role in HTLV-I-associated pathology. AIDS Res Hum Retroviruses. 1993 Feb; 9(2):105-7.
-
Cantor H, Crump AL, Raman VK, Liu H, Markowitz JS, Grusby MJ, Glimcher LH. Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products. Immunol Rev. 1993 Feb; 131:27-42.
-
Patarca R, Saavedra RA, Cantor H. Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene. Crit Rev Immunol. 1993; 13(3-4):225-46.
-
Liu H, Lampe MA, Iregui MV, Cantor H. Clonal unresponsiveness results from an interaction between staphylococcal enterotoxin B and T cells expressing unexpected V beta elements. Int Immunol. 1992 Aug; 4(8):851-9.
-
Lampe MA, Patarca R, Iregui MV, Cantor H. Polyclonal B cell activation by the Eta-1 cytokine and the development of systemic autoimmune disease. J Immunol. 1991 Nov 1; 147(9):2902-6.
-
Liu H, Lampe MA, Iregui MV, Cantor H. Conventional antigen and superantigen may be coupled to distinct and cooperative T-cell activation pathways. Proc Natl Acad Sci U S A. 1991 Oct 1; 88(19):8705-9.
-
Patarca R, Wei FY, Iregui MV, Cantor H. Differential induction of interferon gamma gene expression after activation of CD4+ T cells by conventional antigen and Mls superantigen. Proc Natl Acad Sci U S A. 1991 Apr 1; 88(7):2736-9.
-
Patarca R, Wei FY, Singh P, Morasso MI, Cantor H. Dysregulated expression of the T cell cytokine Eta-1 in CD4-8- lymphocytes during the development of murine autoimmune disease. J Exp Med. 1990 Oct 1; 172(4):1177-83.
-
Itoh T, Rao A, O'Brien D, Nghiem P, Cantor H. Limiting dilution analysis of ontogeny of self- and allo-reactive thymocytes of C57BL/6J mouse. Thymus. 1990 Sep; 16(2):89-98.
-
Patarca R, Singh RP, Wei FY, Iregui MV, Singh P, Schwartz J, Cantor H. Alternative pathways of T-cell activation and positive clonal selection. Immunol Rev. 1990 Aug; 116:85-100.
-
Singh RP, Patarca R, Schwartz J, Singh P, Cantor H. Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effect upon macrophages in vivo. J Exp Med. 1990 Jun 1; 171(6):1931-42.
-
Patarca R, Singh RP, Durfee T, Freeman G, Blattner FR, Cantor H. Definition of T-cell specific DNA-binding factors that interact with a 3'-silencer in the CD4+ T-cell gene Rpt-1. Gene. 1989 Dec 28; 85(2):461-9.
-
Abromson-Leeman S, Laning J, Cantor H, Dorf ME. Isolation of antigen-specific T cell clones from nonresponder mice. Eur J Immunol. 1988 Jan; 18(1):145-52.
-
Friedman S, Sillcocks D, Cantor H. Alloreactivity of an OVA-specific T-cell clone. I. Stimulation by class II MHC and novel non-MHC B-cell determinants. Immunogenetics. 1987; 26(4-5):193-203.
-
DeKruyff RH, Ju ST, Laning J, Cantor H, Dorf ME. Activation requirements of cloned inducer T cells. III. Need for two stimulator cells in the response of a cloned line to Mls determinants. J Immunol. 1986 Aug 15; 137(4):1109-14.
-
Abromson-Leeman SR, Der Simonian H, Clabby M, Cantor H. Analysis of insulin-specific T cell clones. I. Strategy for production of clonotypic antibody. J Immunol. 1986 May 1; 136(9):3184-8.
-
Uchida N, Cone RD, Freeman GJ, Mulligan RC, Cantor H. High efficiency gene transfer into murine T cell clones using a retroviral vector. J Immunol. 1986 Mar 1; 136(5):1876-9.
-
Dekruyff RH, Cantor H, Dorf ME. Activation requirements of cloned inducer T cells. II. The failure of some clones to respond to antigen presented by activated B cells. J Immunol. 1986 Jan; 136(2):446-51.
-
Shen FW, Saga Y, Litman G, Freeman G, Tung JS, Cantor H, Boyse EA. Cloning of Ly-5 cDNA. Proc Natl Acad Sci U S A. 1985 Nov; 82(21):7360-3.
-
DeKruyff R, Clayberger C, Cantor H, Dorf ME. Activation requirements of cloned inducer T cells. I. Differential inhibition by anti-L3T4 or anti-I-A is determined by the accessory cell population. J Immunol. 1985 Oct; 135(4):2243-8.
-
DeKruyff R, Clayberger C, Fay R, Cantor H. B cell activation: role of dendritic and T cell factors in the response to thymic-independent and -dependent antigens. J Immunol. 1985 May; 134(5):2860-6.
-
Friedman S, Sillcocks D, Rao A, Faas S, Cantor H. A subset of Ly-1 inducer T cell clones activates B cell proliferation but directly inhibits subsequent IgG secretion. J Exp Med. 1985 Apr 1; 161(4):785-804.
-
Puri J, Abromson-Leeman S, Cantor H. Antigen processing by macrophages: definition of the ligand recognized by T-inducer cells. Eur J Immunol. 1985 Apr; 15(4):362-8.
-
Clayberger C, DeKruyff RH, Cantor H. T cell regulation of antibody responses: an I-A-specific, autoreactive T cell collaborates with antigen-specific helper T cells to promote IgG responses. J Immunol. 1985 Feb; 134(2):691-4.
-
Rennick DM, Lee FD, Yokota T, Arai KI, Cantor H, Nabel GJ. A cloned MCGF cDNA encodes a multilineage hematopoietic growth factor: multiple activities of interleukin 3. J Immunol. 1985 Feb; 134(2):910-4.
-
Clayberger C, DeKruyff RH, Fay R, Huber B, Cantor H. Evidence for defects in accessory and T cell subsets in mice expressing the xid defect. J Mol Cell Immunol. 1985; 2(2):61-9.
-
DeKruyff RH, Clayberger C, Cantor H. Monoclonal helper T cells induce B cell responses to T-independent antigens: antigen-specific T cells are directly stimulated by activated B cells in the absence of antigen. J Immunol. 1985 Jan; 134(1):86-90.
-
Clayberger C, DeKruyff RH, Fay R, Cantor H. Identification of a unique B-cell-stimulating factor produced by a cloned dendritic cell. Proc Natl Acad Sci U S A. 1985 Jan; 82(1):183-7.
-
Clayberger C, DeKruyff RH, Fay R, Pavlakis M, Cantor H. Immunoregulation of T-dependent responses by a cloned dendritic cell. J Immunol. 1984 Sep; 133(3):1174-8.
-
Razin E, Stevens RL, Austen KF, Caulfield JP, Hein A, Liu FT, Clabby M, Nabel G, Cantor H, Friedman S. Cloned mouse mast cells derived from immunized lymph node cells and from foetal liver cells exhibit characteristics of bone marrow-derived mast cells containing chondroitin sulphate E proteoglycan. Immunology. 1984 Jul; 52(3):563-75.
-
Klyczek KK, Cantor H, Hayes CE. T cell surface I-J glycoprotein. Concerted action of chromosome-4 and -17 genes forms an epitope dependent on alpha-D-mannosyl residues. J Exp Med. 1984 Jun 1; 159(6):1604-17.
-
Clayberger C, Dekruyff RH, Cantor H. Immunoregulatory activities of autoreactive T cells: an I-A-specific T cell clone mediates both help and suppression of antibody responses. J Immunol. 1984 May; 132(5):2237-43.
-
Rao A, Faas SJ, Cantor H. Analogs that compete for antigen binding to an arsonate-reactive T-cell clone inhibit the functional response to arsonate. Cell. 1984 Apr; 36(4):889-95.
-
Rao A, Ko WW, Faas SJ, Cantor H. Binding of antigen in the absence of histocompatibility proteins by arsonate-reactive T-cell clones. Cell. 1984 Apr; 36(4):879-88.
-
Hayes CE, Klyczek KK, Krum DP, Whitcomb RM, Hullett DA, Cantor H. Chromosome 4 Jt gene controls murine T cell surface I-J expression. Science. 1984 Feb 10; 223(4636):559-63.
-
Yokota T, Lee F, Rennick D, Hall C, Arai N, Mosmann T, Nabel G, Cantor H, Arai K. Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells. Proc Natl Acad Sci U S A. 1984 Feb; 81(4):1070-4.
-
Rao A, Faas SJ, Cantor H. Activation specificity of arsonate-reactive T cell clones. Structural requirements for hapten recognition and comparison with monoclonal antibodies. J Exp Med. 1984 Feb 1; 159(2):479-94.
-
Hu SK, Eardley DD, Gershon RK, Cantor H. Acquisition of paralytic activity by inducer cells. J Mol Cell Immunol. 1984; 1(2):91-100.
-
Cone RE, Rosenstein RW, Janeway CA, Iverson GM, Murray JH, Cantor H, Fresno M, Mattingly JA, Cramer M, Krawinkel U, et al. Affinity-purified antigen-specific products produced by T cells share epitopes recognized by heterologous antisera raised against several different antigen-specific products from T cells. Cell Immunol. 1983 Dec; 82(2):232-45.
-
Dekruyff RH, Clayberger C, Cantor H. Hapten reactive inducer T cells. II. Evidence that a secreted form of the T cell receptor induces antibody production. J Exp Med. 1983 Dec 1; 158(6):1881-94.
-
Rao A, Faas SJ, Miller LJ, Riback PS, Cantor H. Lysis of inducer T cell clones by activated macrophages and macrophage-like cell lines. J Exp Med. 1983 Oct 1; 158(4):1243-58.
-
Abromson-Leeman SR, Cantor H. Specificity of T cell clones for antigen and autologous major histocompatibility complex products determines specificity for foreign major histocompatibility complex products. J Exp Med. 1983 Aug 1; 158(2):428-37.
-
Freeman GJ, Clayberger C, DeKruyff R, Rosenblum DS, Cantor H. Sequential expression of new gene programs in inducer T-cell clones. Proc Natl Acad Sci U S A. 1983 Jul; 80(13):4094-8.
-
Clayberger C, Dekruyff RH, Aisenberg J, Cantor H. Hapten-reactive inducer T cells. I. Definition of two classes of hapten-specific inducer cells. J Exp Med. 1983 Jun 1; 157(6):1906-19.
-
Hu SK, Eardley DD, Cantor H, Gershon RK. Definition of two pathways for generation of suppressor T-cell activity. Proc Natl Acad Sci U S A. 1983 Jun; 80(12):3779-81.
-
Rao A, Mizel SB, Cantor H. Disparate functional properties of two interleukin 1-responsive Ly-1+2- T cell clones: distinction of T cell growth factor and T cell-replacing factor activities. J Immunol. 1983 Apr; 130(4):1743-8.
-
Dvorak AM, Galli SJ, Marcum JA, Nabel G, der Simonian H, Goldin J, Monahan RA, Pyne K, Cantor H, Rosenberg RD, Dvorak HF. Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells. J Exp Med. 1983 Mar 1; 157(3):843-61.
-
Galli SJ, Dvorak AM, Marcum JA, Nabel G, Goldin JM, Rosenberg RD, Cantor H, Dvorak HF. Mouse mast cell clones: modulation of functional maturity in vitro. Monogr Allergy. 1983; 18:166-70.
-
Rao A, Allard WJ, Hogan PG, Rosenson RS, Cantor H. Alloreactive T-cell clones. Ly phenotypes predict both function and specificity for major histocompatibility complex products. Immunogenetics. 1983; 17(2):147-65.
-
Galli SJ, Dvorak AM, Marcum JA, Ishizaka T, Nabel G, Der Simonian H, Pyne K, Goldin JM, Rosenberg RD, Cantor H, Dvorak HF. Mast cell clones: a model for the analysis of cellular maturation. J Cell Biol. 1982 Nov; 95(2 Pt 1):435-44.
-
Fresno M, Der Simonian H, Nabel G, Cantor H. Proteins synthesized by inducer T cells: evidence for a mitogenic peptide shared by inducer molecules that stimulate different cell types. Cell. 1982 Oct; 30(3):707-13.
-
Nabel G, Allard WJ, Cantor H. A cloned cell line mediating natural killer cell function inhibits immunoglobulin secretion. J Exp Med. 1982 Aug 1; 156(2):658-63.
-
Galli SJ, Dvorak AM, Ishizaka T, Nabel G, Der Simonian H, Cantor H, Dvorak HF. A cloned cell with NK function resembles basophils by ultrastructure and expresses IgE receptors. Nature. 1982 Jul 15; 298(5871):288-90.
-
Glimcher LH, Cantor H. T-cell sets that control B-cell secretion of antigen-specific immunoglobulin also control secretion of nonspecific immunoglobulin. Cell Immunol. 1982 Jul 1; 70(2):271-6.
-
Dvorak AM, Nabel G, Pyne K, Cantor H, Dvorak HF, Galli SJ. Ultrastructural identification of the mouse basophil. Blood. 1982 Jun; 59(6):1279-85.
-
Fresno M, McVay-Boudreau L, Cantor H. Antigen-specific T lymphocyte clones. III. Papain splits purified T suppressor molecules into two functional domains. J Exp Med. 1982 Apr 1; 155(4):981-93.
-
Cantor H. Specific regulation of immune responses by products of T cell clones. Pharmacol Rev. 1982 Mar; 34(1):63-4.
-
Cantor H. The immune response to agents that cause acute and chronic diseases. J Cell Biochem. 1982; 20(2):105-12.
-
Yamauchi K, Murphy D, Cantor H, Gershon RK. Analysis of an antigen-specific H-2-restricted cell-free products(s) made by "I-J-" Ly-2 cells (Ly-2 TsF) that suppresses Ly-2 cell-depleted spleen cell activity. Eur J Immunol. 1981 Nov; 11(11):913-8.
-
Yamauchi K, Murphy D, Cantor H, Gershon RK. Analysis of antigen-specific, Ig-restricted cell-free material made by I-J+ Ly-1 cells (Ly-1 TsiF) that induces Ly-2+ cells to express suppressive activity. Eur J Immunol. 1981 Nov; 11(11):905-12.
-
Cantor H. Regulation of immune responses: analysis with lymphocyte clones. Cell. 1981 Jul; 25(1):7-8.
-
Gershon RK, Eardley DD, Durum S, Green DR, Shen FW, Yamauchi K, Cantor H, Murphy DB. Contrasuppression. A novel immunoregulatory activity. J Exp Med. 1981 Jun 1; 153(6):1533-46.
-
Nabel G, Bucalo LR, Allard J, Wigzell H, Cantor H. Multiple activities of a cloned cell line mediating natural killer cell function. J Exp Med. 1981 Jun 1; 153(6):1582-91.
-
Nabel G, Galli SJ, Dvorak AM, Dvorak HF, Cantor H. Inducer T lymphocytes synthesize a factor that stimulates proliferation of cloned mast cells. Nature. 1981 May 28; 291(5813):332-4.
-
Fresno M, Nabel G, McVay-Boudreau L, Furthmayer H, Cantor H. Antigen-specific T lymphocyte clones. I. Characterization of a T lymphocyte clone expressing antigen-specific suppressive activity. J Exp Med. 1981 May 1; 153(5):1246-59.
-
Fresno M, McVay-Boudreau L, Nabel G, Cantor H. Antigen-specific T lymphocyte clones. II. Purification and biological characterization of an antigen-specific suppressive protein synthesized by cloned T cells. J Exp Med. 1981 May 1; 153(5):1260-74.
-
Nabel G, Greenberger JS, Sakakeeny MA, Cantor H. Multiple biologic activities of a cloned inducer T-cell population. Proc Natl Acad Sci U S A. 1981 Feb; 78(2):1157-61.
-
Bhan AK, Perry LL, Cantor H, McCluskey RT, Benacerraf B, Greene MI. The role of T cell sets in the rejection of a methylcholanthrene-induced sarcoma (S1509a) in syngeneic mice. Am J Pathol. 1981 Jan; 102(1):20-7.
-
Nabel G, Fresno M, Chessman A, Cantor H. Use of cloned populations of mouse lymphocytes to analyze cellular differentiation. Cell. 1981 Jan; 23(1):19-28.
-
Kühner AL, Cantor H, David JR. Ly phenotype of lymphocytes producing murine migration inhibitory factor (MIF). J Immunol. 1980 Sep; 125(3):1117-9.
-
Minato N, Reid L, Cantor H, Lengyel P, Bloom BR. Mode of regulation of natural killer cell activity by interferon. J Exp Med. 1980 Jul 1; 152(1):124-37.
-
Finberg R, Cantor H, Benacerraf B, Burakoff S. The origins of alloreactivity: differentiation of prekiller cells to viral infection results in alloreactive cytolytic T lymphocytes. J Immunol. 1980 Apr; 124(4):1858-60.
-
Zubler RH, Cantor H, Benacerraf B, Germain RN. Feedback suppression of the immune response in vitro. I. Activity of antigen-stimulated B cells. J Exp Med. 1980 Mar 1; 151(3):667-80.
-
Leclerc JC, Cantor H. T cell-mediated immunity to oncornavirus-induced tumors. II. Ability of different T cell sets to prevent tumor growth in vivo. J Immunol. 1980 Feb; 124(2):851-4.
-
Leclerc JC, Cantor H. T cell-mediated immunity to oncornavirus-induced tumors. I. Ly phenotype of precursor and effector cytolytic T lymphocytes. J Immunol. 1980 Feb; 124(2):846-50.
-
L'age-Stehr J, Teichmann H, Gershon RK, Cantor H. Stimulation of regulatory T cell circuits by immunoglobulin-dependent structures on activated B cells. Eur J Immunol. 1980 Jan; 10(1):21-6.
-
Eardley DD, Murphy DB, Kemp JD, Shen FW, Cantor H, Gershon RK. Ly-1 inducer and Ly-1,2 acceptor T cells in the feedback suppression circuit bear an I-J-subregion controlled determinant. Immunogenetics. 1980; 11(6):549-57.
-
Woodland RT, Cantor H. V(H) gene products allow specific communication among immunologic cell sets. Contemp Top Immunobiol. 1980; 11:227-44.
-
Boyse EA, Cantor H. Cellular communication and differentiation. Arthritis Rheum. 1979 Nov; 22(11):1153-60.
-
Eardley DD, Shen FW, Cantor H, Gershon RK. Genetic control of immunoregulatory circuits. Genes linked to the Ig locus govern communication between regulatory T-cell sets. J Exp Med. 1979 Jul 1; 150(1):44-50.
-
Cantor H, Gershon RK. Immunological circuits: cellular composition. Fed Proc. 1979 Jun; 38(7):2058-64.
-
Eardley DD, Kemp J, Shen FW, Cantor H, Gershon RK. Immunoregulatory circuits among T cell sets: effect of mode of immunization on determining which Lyl T cell sets will be activated. J Immunol. 1979 May; 122(5):1663-5.
-
Kasai M, Leclerc JC, McVay-Boudreau L, Shen FW, Cantor H. Direct evidence that natural killer cells in nonimmune spleen cell populations prevent tumor growth in vivo. J Exp Med. 1979 May 1; 149(5):1260-4.
-
Cantor H, Kasai M, Shen FW, Leclerc JC, Glimcher L. Immunogenetic analysis of "natural killer" activity in the mouse. Immunol Rev. 1979; 44:3-12.
-
Cantor H. Control of the immune system by inhibitor and inducer T lymphocytes. Annu Rev Med. 1979; 30:269-77.
-
de Sousa M, Freitas A, Huber B, Cantor H, Boyse EA. Migratory patterns of the Ly subsets of T lymphocytes in the mouse. Adv Exp Med Biol. 1979; 114:51-4.
-
Burakoff SJ, Finberg R, Glimcher L, Lemonnier F, Benacerraf B, Cantor H. The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens. J Exp Med. 1978 Nov 1; 148(5):1414-22.
-
Cantor H, Hugenberger J, McVay-Boudreau L, Eardley DD, Kemp J, Shen FW, Gershon RK. Immunoregulatory circuits among T-cell sets. Identification of a subpopulation of T-helper cells that induces feedback inhibition. J Exp Med. 1978 Oct 1; 148(4):871-7.
-
Finberg R, Burakoff SJ, Cantor H, Benacerraf B. Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells. Proc Natl Acad Sci U S A. 1978 Oct; 75(10):5145-9.
-
Stanton TH, Calkins CE, Jandinski J, Schendel DJ, Stutman O, Cantor H, Boyse EA. The Qa-1 antigenic system. Relation of Qa-1 phenotypes to lymphocyte sets, mitogen responses, and immune functions. J Exp Med. 1978 Oct 1; 148(4):963-73.
-
Woodland R, Cantor H. Idiotype-specific T helper cells are required to induce idiotype-positive B memory cells to secrete antibody. Eur J Immunol. 1978 Aug; 8(8):600-6.
-
Ward K, Cantor H, Nisonoff A. Analysis of the cellular basis of idiotype-specific suppression. J Immunol. 1978 Jun; 120(6):2016-9.
-
Gershon RK, Eardley DD, Naidorf K, Cantor H. Association of defective feedback suppressor T cell activity with autoimmunity in NZB mice. Arthritis Rheum. 1978 Jun; 21(5 Suppl):S180-4.
-
Cone RE, Huber B, Cantor H, Gershon RK. Molecular identification of a surface structure on B cells (Lyb-3) and its relationship to B cell triggering. J Immunol. 1978 May; 120(5):1733-40.
-
Cantor H, McVay-Boudreau L, Hugenberger J, Naidorf K, Shen FW, Gershon RK. Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice. J Exp Med. 1978 Apr 1; 147(4):1116-25.
-
Eardley DD, Hugenberger J, McVay-Boudreau L, Shen FW, Gershon RK, Cantor H. Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition. J Exp Med. 1978 Apr 1; 147(4):1106-15.
-
Boyse EA, Cantor H. Immunogenetic aspects of biologic communication: a hypothesis of evolution by program duplication. Birth Defects Orig Artic Ser. 1978; 14(2):249-83.
-
Boyse EA, Cantor H. Surface characteristics of T-lymphocyte subpopulations. Hosp Pract. 1977 Apr; 12(4):81-8.
-
Cantor H, Boyse EA. Regulation of cellular and humoral immune responses by T-cell subclasses. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 1:23-32.
-
Glimcher L, Shen FW, Cantor H. Identification of a cell-surface antigen selectively expressed on the natural killer cell. J Exp Med. 1977 Jan 1; 145(1):1-9.
-
Cantor H, Boyse E. Regulation of the immune response by T-cell subclasses. Contemp Top Immunobiol. 1977; 7:47-67.
-
Huber B, Gershon RK, Cantor H. Identification of a B-cell surface structure involved in antigen-dependent triggering: absence of this structure on B cells from CBA/N mutant mice. J Exp Med. 1977 Jan 1; 145(1):10-20.
-
Cantor H, Boyse EA. Lymphocytes as models for the study of mammalian cellular differentiation. Immunol Rev. 1977 Jan; 33:105-24.
-
Weitzman S, Shen FW, Cantor H. Maintenance of hyporesponsiveness to antigen by a distinct subclass of T lymphocytes. J Immunol. 1976 Dec; 117(6):2209-12.
-
Huber B, Cantor H, Shen FW, Boyse EA. Independent differentiative pathways of Ly1 and Ly23 subclasses of T cells. Experimental production of mice deprived of selected T-cell subclasses. J Exp Med. 1976 Oct 1; 144(4):1128-33.
-
Silverstone AE, Cantor H, Goldstein G, Baltimore D. Terminal deoxynucleotidyl transferase is found in prothymocytes. J Exp Med. 1976 Aug 1; 144(2):543-8.
-
Herzenberg LA, Okumura K, Cantor H, Sato VL, Shen FW, Boyse EA, Herzenberg LA. T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells. J Exp Med. 1976 Aug 1; 144(2):330-44.
-
Jandinski J, Cantor H, Tadakuma T, Peavy DL, Pierce CW. Separation of helper T cells from suppressor T cells expressing different Ly components. I. Polyclonal activation: suppressor and helper activities are inherent properties of distinct T-cell subclasses. J Exp Med. 1976 Jun 1; 143(6):1382-90.
-
Cantor H, Shen FW, Boyse EA. Separation of helper T cells from suppressor T cells expressing different Ly components. II. Activation by antigen: after immunization, antigen-specific suppressor and helper activities are mediated by distinct T-cell subclasses. J Exp Med. 1976 Jun 1; 143(6):1391-40.
-
Huber B, Devinsky O, Gershon RK, Cantor H. Cell-mediated immunity: delayed-type hypersensitivity and cytotoxic responses are mediated by different T-cell subclasses. J Exp Med. 1976 Jun 1; 143(6):1534-9.
-
Cantor H, Weissman I. Development and function of subpopulations of thymocytes and T lymphocytes. Prog Allergy. 1976; 20:1-64.
-
Cantor H, Boyse EA. Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen. J Exp Med. 1975 Jun 1; 141(6):1376-89.
-
Cantor H, Boyse EA. Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity. J Exp Med. 1975 Jun 1; 141(6):1390-9.
-
Simpson E, Cantor H. Regulation of the immune response by subclasses of T lymphocytes. II. The effect of adult thymectomy upon humoral and cellular responses in mice. Eur J Immunol. 1975 May; 5(5):337-43.
-
Cantor H, Simpson E. Regulation of the immune response by subclasses of T lymphocytes. I. Interactions between pre-killer T cells and regulatory T cells obtained from peripheral lymphoid tissues of mice. Eur J Immunol. 1975 May; 5(5):330-6.
-
Cantor H, Boyse EA. Development and function of subclasses of T cells. J Reticuloendothel Soc. 1975 Feb; 17(2):115-8.
-
Cantor H, Simpson E, Sato VL, Fathman CG, Herzenberg LA. Characterization of subpopulations of T lymphocytes. I. Separation and functional studies of peripheral T-cells binding different amounts of fluorescent anti-Thy 1.2 (theta) antibody using a fluorescence-activated cell sorter (FACS). Cell Immunol. 1975 Jan; 15(1):180-96.
-
Simpson E, O'Hopp S, Harrison M, Mosier D, Melief K, Cantor H. Immunological disease induced by injecting F1 lymphoid cells into certain parental strains. Immunology. 1974 Dec; 27(6):989-1007.
-
Cantor H, Jandinski J. The relationship of cell division to the generation of cytotoxic activity in mixed lymphocyte culture. J Exp Med. 1974 Dec 1; 140(6):1712-6.
-
Cantor H, Mosier DE. Maturation of reactivity to histocompatibility antigens. Transplant Proc. 1972 Jun; 4(2):159-62.
-
Cantor H, Greaves M. Another approach to the problem of disparities between HL-A serotyping and mixed lymphocyte culturte response. Transplant Proc. 1972 Jun; 4(2):227-30.
-
Cantor H, Asofsky R. Synergy among lymphoid cells mediating the graft-versus-host response. 3. Evidence for interaction between two types of thymus-derived cells. J Exp Med. 1972 Apr 1; 135(4):764-79.
-
Cantor H. The effects of anti-theta antiserum upon graft-versus-host activity of spleen and lymph node cells. Cell Immunol. 1972 Mar; 3(3):461-9.
-
Cantor H. T cells and the immune response. Prog Biophys Mol Biol. 1972; 25:73-82.
-
Cantor H. Differential migration of helper and precursor spleen cells following immunization. Eur J Immunol. 1971 Dec; 1(6):462-4.
-
Mosier D, Cantor H. Functional maturation of mouse thymic lymphocytes. Eur J Immunol. 1971 Dec; 1(6):459-61.
-
Cantor H, Asofsky R, Levy HB. The effect of polyinosinic-polycytidylic acid upon graft-vs-host activity in BALB/c mice. J Immunol. 1970 Apr; 104(4):1035-8.
-
Cantor H, Asofsky R. Synergy among lymphoid cells mediating the graft-versus-host response. II. Synergy in graft-versus-host reactions produced by Balb-c lymphoid cells of differing anatomic origin. J Exp Med. 1970 Feb; 131(2):235-46.
-
Cantor H, Asofsky R, Talal N. Synergy among lymphoid cells mediating the graft-versus-host response. I. Synergy in graft-versus-host reactions produced by cells from NZB-Bl mice. J Exp Med. 1970 Feb; 131(2):223-34.
-
Cantor H, Mandel MA, Asofsky R. Studies of thoracic duct lymphocytes of mice. II. A quantitative comparison of the capacity of thoracic duct lymphocytes and other lymphoid cells to induce graft-versus-host reactions. J Immunol. 1970 Feb; 104(2):409-13.
This graph shows the total number of publications by year.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
|
Cantor's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts  Derived automatically from this person's publications. _
Co-Authors People in Profiles who have published with this person. _
Similar People People who share similar concepts with this person. _
Same Department
People who are also in this person's primary department.
Physical Neighbors People whose addresses are nearby this person. _
|