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Last Name
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Alan Jay Grodzinsky, SC.D.

TitleMember of the Affiliated Faculty of the Harvard-MIT Division of Health Sciences and Technology
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology
Address38-377 M.I.T.
Cambridge MA 02139
Phone617/253-4969
Fax617/258-5239

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nia HT, Bozchalooi IS, Li Y, Han L, Hung HH, Frank E, Youcef-Toumi K, Ortiz C, Grodzinsky A. High-Bandwidth AFM-Based Rheology Reveals that Cartilage is Most Sensitive to High Loading Rates at Early Stages of Impairment. Biophys J. 2013 Apr 2; 104(7):1529-37.
    View in: PubMed
  2. Lee CM, Kisiday JD, McIlwraith CW, Grodzinsky AJ, Frisbie DD. Synoviocytes protect cartilage from the effects of injury in vitro. BMC Musculoskelet Disord. 2013; 14:54.
    View in: PubMed
  3. Byun S, Sinskey YL, Lu YC, Ort T, Kavalkovich K, Sivakumar P, Hunziker EB, Frank EH, Grodzinsky AJ. Transport of anti-IL-6 antigen binding fragments into cartilage and the effects of injury. Arch Biochem Biophys. 2013 Apr 1; 532(1):15-22.
    View in: PubMed
  4. Lee CM, Kisiday JD, McIlwraith CW, Grodzinsky AJ, Frisbie DD. Development of an in vitro model of injury-induced osteoarthritis in cartilage explants from adult horses through application of single-impact compressive overload. Am J Vet Res. 2013 Jan; 74(1):40-7.
    View in: PubMed
  5. Lee HY, Han L, Roughley PJ, Grodzinsky AJ, Ortiz C. Age-related nanostructural and nanomechanical changes of individual human cartilage aggrecan monomers and their glycosaminoglycan side chains. J Struct Biol. 2013 Mar; 181(3):264-73.
    View in: PubMed
  6. Hufeland M, Schünke M, Grodzinsky AJ, Imgenberg J, Kurz B. Response of mature meniscal tissue to a single injurious compression and interleukin-1 in vitro. Osteoarthritis Cartilage. 2013 Jan; 21(1):209-16.
    View in: PubMed
  7. Ahn AC, Gow BJ, Martinsen OG, Zhao M, Grodzinsky AJ, Baikie ID. Applying the Kelvin probe to biological tissues: theoretical and computational analyses. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Jun; 85(6 Pt 1):061901.
    View in: PubMed
  8. Nia HT, Han L, Li Y, Ortiz C, Grodzinsky A. Poroelasticity of cartilage at the nanoscale. Biophys J. 2011 Nov 2; 101(9):2304-13.
    View in: PubMed
  9. Miller RE, Kopesky PW, Grodzinsky AJ. Growth factor delivery through self-assembling peptide scaffolds. Clin Orthop Relat Res. 2011 Oct; 469(10):2716-24.
    View in: PubMed
  10. Gardiner BS, Zhang L, Smith DW, Pivonka P, Grodzinsky AJ. A mathematical model for targeting chemicals to tissues by exploiting complex degradation. Biol Direct. 2011; 6:46.
    View in: PubMed
  11. Lu YC, Evans CH, Grodzinsky AJ. Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines. Arthritis Res Ther. 2011; 13(5):R142.
    View in: PubMed
  12. Rolauffs B, Rothdiener M, Bahrs C, Badke A, Weise K, Kuettner KE, Kurz B, Aurich M, Grodzinsky AJ, Aicher WK. Onset of preclinical osteoarthritis: the angular spatial organization permits early diagnosis. Arthritis Rheum. 2011 Jun; 63(6):1637-47.
    View in: PubMed
  13. Han L, Frank EH, Greene JJ, Lee HY, Hung HH, Grodzinsky AJ, Ortiz C. Time-dependent nanomechanics of cartilage. Biophys J. 2011 Apr 6; 100(7):1846-54.
    View in: PubMed
  14. Miller RE, Grodzinsky AJ, Cummings K, Plaas AH, Cole AA, Lee RT, Patwari P. Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate. Arthritis Rheum. 2010 Dec; 62(12):3686-94.
    View in: PubMed
  15. Rolauffs B, Muehleman C, Li J, Kurz B, Kuettner KE, Frank E, Grodzinsky AJ. Vulnerability of the superficial zone of immature articular cartilage to compressive injury. Arthritis Rheum. 2010 Oct; 62(10):3016-27.
    View in: PubMed
  16. Kopesky PW, Vanderploeg EJ, Kisiday JD, Frisbie DD, Sandy JD, Grodzinsky AJ. Controlled delivery of transforming growth factor ß1 by self-assembling peptide hydrogels induces chondrogenesis of bone marrow stromal cells and modulates Smad2/3 signaling. Tissue Eng Part A. 2011 Jan; 17(1-2):83-92.
    View in: PubMed
  17. Miller RE, Grodzinsky AJ, Vanderploeg EJ, Lee C, Ferris DJ, Barrett MF, Kisiday JD, Frisbie DD. Effect of self-assembling peptide, chondrogenic factors, and bone marrow-derived stromal cells on osteochondral repair. Osteoarthritis Cartilage. 2010 Dec; 18(12):1608-19.
    View in: PubMed
  18. Lee HY, Kopesky PW, Plaas A, Sandy J, Kisiday J, Frisbie D, Grodzinsky AJ, Ortiz C. Adult bone marrow stromal cell-based tissue-engineered aggrecan exhibits ultrastructure and nanomechanical properties superior to native cartilage. Osteoarthritis Cartilage. 2010 Nov; 18(11):1477-86.
    View in: PubMed
  19. Byun S, Tortorella MD, Malfait AM, Fok K, Frank EH, Grodzinsky AJ. Transport and equilibrium uptake of a peptide inhibitor of PACE4 into articular cartilage is dominated by electrostatic interactions. Arch Biochem Biophys. 2010 Jul; 499(1-2):32-9.
    View in: PubMed
  20. Hosseini A, Van de Velde SK, Kozanek M, Gill TJ, Grodzinsky AJ, Rubash HE, Li G. In-vivo time-dependent articular cartilage contact behavior of the tibiofemoral joint. Osteoarthritis Cartilage. 2010 Jul; 18(7):909-16.
    View in: PubMed
  21. Lemke AK, Sandy JD, Voigt H, Dreier R, Lee JH, Grodzinsky AJ, Mentlein R, Fay J, Schünke M, Kurz B. Interleukin-1alpha treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2. Cell Tissue Res. 2010 Apr; 340(1):179-88.
    View in: PubMed
  22. Kopesky PW, Lee HY, Vanderploeg EJ, Kisiday JD, Frisbie DD, Plaas AH, Ortiz C, Grodzinsky AJ. Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes. Matrix Biol. 2010 Jun; 29(5):427-38.
    View in: PubMed
  23. Kopesky PW, Vanderploeg EJ, Sandy JS, Kurz B, Grodzinsky AJ. Self-assembling peptide hydrogels modulate in vitro chondrogenesis of bovine bone marrow stromal cells. Tissue Eng Part A. 2010 Feb; 16(2):465-77.
    View in: PubMed
  24. Rolauffs B, Williams JM, Aurich M, Grodzinsky AJ, Kuettner KE, Cole AA. Proliferative remodeling of the spatial organization of human superficial chondrocytes distant from focal early osteoarthritis. Arthritis Rheum. 2010 Feb; 62(2):489-98.
    View in: PubMed
  25. Zhang L, Gardiner BS, Smith DW, Pivonka P, Grodzinsky AJ. On the role of diffusible binding partners in modulating the transport and concentration of proteins in tissues. J Theor Biol. 2010 Mar 7; 263(1):20-9.
    View in: PubMed
  26. Kisiday JD, Vanderploeg EJ, McIlwraith CW, Grodzinsky AJ, Frisbie DD. Mechanical injury of explants from the articulating surface of the inner meniscus. Arch Biochem Biophys. 2010 Feb 15; 494(2):138-44.
    View in: PubMed
  27. Lee B, Han L, Frank EH, Chubinskaya S, Ortiz C, Grodzinsky AJ. Dynamic mechanical properties of the tissue-engineered matrix associated with individual chondrocytes. J Biomech. 2010 Feb 10; 43(3):469-76.
    View in: PubMed
  28. Sui Y, Lee JH, DiMicco MA, Vanderploeg EJ, Blake SM, Hung HH, Plaas AH, James IE, Song XY, Lark MW, Grodzinsky AJ. Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage. Arthritis Rheum. 2009 Oct; 60(10):2985-96.
    View in: PubMed
  29. Kisiday JD, Frisbie DD, McIlwraith CW, Grodzinsky AJ. Dynamic compression stimulates proteoglycan synthesis by mesenchymal stem cells in the absence of chondrogenic cytokines. Tissue Eng Part A. 2009 Oct; 15(10):2817-24.
    View in: PubMed
  30. Chai DH, Arner EC, Griggs DW, Grodzinsky AJ. Alphav and beta1 integrins regulate dynamic compression-induced proteoglycan synthesis in 3D gel culture by distinct complementary pathways. Osteoarthritis Cartilage. 2010 Feb; 18(2):249-56.
    View in: PubMed
  31. Lee JH, Fitzgerald JB, DiMicco MA, Cheng DM, Flannery CR, Sandy JD, Plaas AH, Grodzinsky AJ. Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production. Arch Biochem Biophys. 2009 Sep; 489(1-2):118-26.
    View in: PubMed
  32. Vanderploeg EJ, Grodzinsky AJ. Can the meniscus affect the nature of a chondrocyte? Osteoarthritis Cartilage. 2009 Aug; 17(8):969-70.
    View in: PubMed
  33. Kisiday JD, Lee JH, Siparsky PN, Frisbie DD, Flannery CR, Sandy JD, Grodzinsky AJ. Catabolic responses of chondrocyte-seeded peptide hydrogel to dynamic compression. Ann Biomed Eng. 2009 Jul; 37(7):1368-75.
    View in: PubMed
  34. Patwari P, Lin SN, Kurz B, Cole AA, Kumar S, Grodzinsky AJ. Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway. Scand J Med Sci Sports. 2009 Aug; 19(4):528-35.
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  35. Ahn AC, Grodzinsky AJ. Relevance of collagen piezoelectricity to "Wolff's Law": a critical review. Med Eng Phys. 2009 Sep; 31(7):733-41.
    View in: PubMed
  36. Wheeler CA, Jafarzadeh SR, Rocke DM, Grodzinsky AJ. IGF-1 does not moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage. Osteoarthritis Cartilage. 2009 Jul; 17(7):944-52.
    View in: PubMed
  37. Stevens AL, Wishnok JS, White FM, Grodzinsky AJ, Tannenbaum SR. Mechanical injury and cytokines cause loss of cartilage integrity and upregulate proteins associated with catabolism, immunity, inflammation, and repair. Mol Cell Proteomics. 2009 Jul; 8(7):1475-89.
    View in: PubMed
  38. Jones AR, Chen S, Chai DH, Stevens AL, Gleghorn JP, Bonassar LJ, Grodzinsky AJ, Flannery CR. Modulation of lubricin biosynthesis and tissue surface properties following cartilage mechanical injury. Arthritis Rheum. 2009 Jan; 60(1):133-42.
    View in: PubMed
  39. Lin Z, Fitzgerald JB, Xu J, Willers C, Wood D, Grodzinsky AJ, Zheng MH. Gene expression profiles of human chondrocytes during passaged monolayer cultivation. J Orthop Res. 2008 Sep; 26(9):1230-7.
    View in: PubMed
  40. Han L, Dean D, Daher LA, Grodzinsky AJ, Ortiz C. Cartilage aggrecan can undergo self-adhesion. Biophys J. 2008 Nov 15; 95(10):4862-70.
    View in: PubMed
  41. Zhang L, Gardiner BS, Smith DW, Pivonka P, Grodzinsky A. A fully coupled poroelastic reactive-transport model of cartilage. Mol Cell Biomech. 2008 Jun; 5(2):133-53.
    View in: PubMed
  42. Pfeiffer E, Vickers SM, Frank E, Grodzinsky AJ, Spector M. The effects of glycosaminoglycan content on the compressive modulus of cartilage engineered in type II collagen scaffolds. Osteoarthritis Cartilage. 2008 Oct; 16(10):1237-44.
    View in: PubMed
  43. Kisiday JD, Kopesky PW, Evans CH, Grodzinsky AJ, McIlwraith CW, Frisbie DD. Evaluation of adult equine bone marrow- and adipose-derived progenitor cell chondrogenesis in hydrogel cultures. J Orthop Res. 2008 Mar; 26(3):322-31.
    View in: PubMed
  44. Tokunou T, Miller R, Patwari P, Davis ME, Segers VF, Grodzinsky AJ, Lee RT. Engineering insulin-like growth factor-1 for local delivery. FASEB J. 2008 Jun; 22(6):1886-93.
    View in: PubMed
  45. Rolauffs B, Williams JM, Grodzinsky AJ, Kuettner KE, Cole AA. Distinct horizontal patterns in the spatial organization of superficial zone chondrocytes of human joints. J Struct Biol. 2008 May; 162(2):335-44.
    View in: PubMed
  46. Stevens AL, Wishnok JS, Chai DH, Grodzinsky AJ, Tannenbaum SR. A sodium dodecyl sulfate-polyacrylamide gel electrophoresis-liquid chromatography tandem mass spectrometry analysis of bovine cartilage tissue response to mechanical compression injury and the inflammatory cytokines tumor necrosis factor alpha and interleukin-1beta. Arthritis Rheum. 2008 Feb; 58(2):489-500.
    View in: PubMed
  47. Wagner T, Eden U, Fregni F, Valero-Cabre A, Ramos-Estebanez C, Pronio-Stelluto V, Grodzinsky A, Zahn M, Pascual-Leone A. Transcranial magnetic stimulation and brain atrophy: a computer-based human brain model study. Exp Brain Res. 2008 Apr; 186(4):539-50.
    View in: PubMed
  48. Fitzgerald JB, Jin M, Chai DH, Siparsky P, Fanning P, Grodzinsky AJ. Shear- and compression-induced chondrocyte transcription requires MAPK activation in cartilage explants. J Biol Chem. 2008 Mar 14; 283(11):6735-43.
    View in: PubMed
  49. Stevens AL, Wheeler CA, Tannenbaum SR, Grodzinsky AJ. Nitric oxide enhances aggrecan degradation by aggrecanase in response to TNF-alpha but not IL-1beta treatment at a post-transcriptional level in bovine cartilage explants. Osteoarthritis Cartilage. 2008 Apr; 16(4):489-97.
    View in: PubMed
  50. Gardiner B, Smith D, Pivonka P, Grodzinsky A, Frank E, Zhang L. Solute transport in cartilage undergoing cyclic deformation. Comput Methods Biomech Biomed Engin. 2007 Aug; 10(4):265-78.
    View in: PubMed
  51. Han L, Dean D, Mao P, Ortiz C, Grodzinsky AJ. Nanoscale shear deformation mechanisms of opposing cartilage aggrecan macromolecules. Biophys J. 2007 Sep 1; 93(5):L23-5.
    View in: PubMed
  52. Dimicco MA, Kisiday JD, Gong H, Grodzinsky AJ. Structure of pericellular matrix around agarose-embedded chondrocytes. Osteoarthritis Cartilage. 2007 Oct; 15(10):1207-16.
    View in: PubMed
  53. Wagner T, Fregni F, Fecteau S, Grodzinsky A, Zahn M, Pascual-Leone A. Transcranial direct current stimulation: a computer-based human model study. Neuroimage. 2007 Apr 15; 35(3):1113-24.
    View in: PubMed
  54. Boubriak I, Pouschuk V, Grodzinsky A, Osborne DJ. Telomeres and seed banks. Tsitol Genet. 2007 Jan-Feb; 41(1):23-9.
    View in: PubMed
  55. Han L, Dean D, Ortiz C, Grodzinsky AJ. Lateral nanomechanics of cartilage aggrecan macromolecules. Biophys J. 2007 Feb 15; 92(4):1384-98.
    View in: PubMed
  56. Zhang L, Gardiner BS, Smith DW, Pivonka P, Grodzinsky A. The effect of cyclic deformation and solute binding on solute transport in cartilage. Arch Biochem Biophys. 2007 Jan 1; 457(1):47-56.
    View in: PubMed
  57. Behera AK, Hildebrand E, Szafranski J, Hung HH, Grodzinsky AJ, Lafyatis R, Koch AE, Kalish R, Perides G, Steere AC, Hu LT. Role of aggrecanase 1 in Lyme arthritis. Arthritis Rheum. 2006 Oct; 54(10):3319-29.
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  58. Ng L, Hung HH, Sprunt A, Chubinskaya S, Ortiz C, Grodzinsky A. Nanomechanical properties of individual chondrocytes and their developing growth factor-stimulated pericellular matrix. J Biomech. 2007; 40(5):1011-23.
    View in: PubMed
  59. Fitzgerald JB, Jin M, Grodzinsky AJ. Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue. J Biol Chem. 2006 Aug 25; 281(34):24095-103.
    View in: PubMed
  60. Patwari P, Cheng DM, Cole AA, Kuettner KE, Grodzinsky AJ. Analysis of the relationship between peak stress and proteoglycan loss following injurious compression of human post-mortem knee and ankle cartilage. Biomech Model Mechanobiol. 2007 Jan; 6(1-2):83-9.
    View in: PubMed
  61. Davis ME, Hsieh PC, Takahashi T, Song Q, Zhang S, Kamm RD, Grodzinsky AJ, Anversa P, Lee RT. Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8155-60.
    View in: PubMed
  62. Wagner T, Fregni F, Eden U, Ramos-Estebanez C, Grodzinsky A, Zahn M, Pascual-Leone A. Transcranial magnetic stimulation and stroke: a computer-based human model study. Neuroimage. 2006 Apr 15; 30(3):857-70.
    View in: PubMed
  63. Dean D, Han L, Grodzinsky AJ, Ortiz C. Compressive nanomechanics of opposing aggrecan macromolecules. J Biomech. 2006; 39(14):2555-65.
    View in: PubMed
  64. Kurz B, Lemke AK, Fay J, Pufe T, Grodzinsky AJ, Schünke M. Pathomechanisms of cartilage destruction by mechanical injury. Ann Anat. 2005 Nov; 187(5-6):473-85.
    View in: PubMed
  65. Seog J, Dean D, Rolauffs B, Wu T, Genzer J, Plaas AH, Grodzinsky AJ, Ortiz C. Nanomechanics of opposing glycosaminoglycan macromolecules. J Biomech. 2005 Sep; 38(9):1789-97.
    View in: PubMed
  66. Lee JH, Fitzgerald JB, Dimicco MA, Grodzinsky AJ. Mechanical injury of cartilage explants causes specific time-dependent changes in chondrocyte gene expression. Arthritis Rheum. 2005 Aug; 52(8):2386-95.
    View in: PubMed
  67. Bathe M, Rutledge GC, Grodzinsky AJ, Tidor B. Osmotic pressure of aqueous chondroitin sulfate solution: a molecular modeling investigation. Biophys J. 2005 Oct; 89(4):2357-71.
    View in: PubMed
  68. Davis ME, Hsieh PC, Grodzinsky AJ, Lee RT. Custom design of the cardiac microenvironment with biomaterials. Circ Res. 2005 Jul 8; 97(1):8-15.
    View in: PubMed
  69. Bathe M, Rutledge GC, Grodzinsky AJ, Tidor B. A coarse-grained molecular model for glycosaminoglycans: application to chondroitin, chondroitin sulfate, and hyaluronic acid. Biophys J. 2005 Jun; 88(6):3870-87.
    View in: PubMed
  70. Patwari P, Gao G, Lee JH, Grodzinsky AJ, Sandy JD. Analysis of ADAMTS4 and MT4-MMP indicates that both are involved in aggrecanolysis in interleukin-1-treated bovine cartilage. Osteoarthritis Cartilage. 2005 Apr; 13(4):269-77.
    View in: PubMed
  71. Buckwalter JA, Mankin HJ, Grodzinsky AJ. Articular cartilage and osteoarthritis. Instr Course Lect. 2005; 54:465-80.
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  72. Kisiday JD, Kurz B, DiMicco MA, Grodzinsky AJ. Evaluation of medium supplemented with insulin-transferrin-selenium for culture of primary bovine calf chondrocytes in three-dimensional hydrogel scaffolds. Tissue Eng. 2005 Jan-Feb; 11(1-2):141-51.
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  73. Lu Y, Adkisson HD, Bogdanske J, Kalscheur V, Maloney W, Cheung R, Grodzinsky AJ, Hruska KA, Markel MD. In vivo transplantation of neonatal ovine neocartilage allografts: determining the effectiveness of tissue transglutaminase. J Knee Surg. 2005 Jan; 18(1):31-42.
    View in: PubMed
  74. Szafranski JD, Grodzinsky AJ, Burger E, Gaschen V, Hung HH, Hunziker EB. Chondrocyte mechanotransduction: effects of compression on deformation of intracellular organelles and relevance to cellular biosynthesis. Osteoarthritis Cartilage. 2004 Dec; 12(12):937-46.
    View in: PubMed
  75. Bathe M, Grodzinsky AJ, Tidor B, Rutledge GC. Optimal linearized Poisson-Boltzmann theory applied to the simulation of flexible polyelectrolytes in solution. J Chem Phys. 2004 Oct 22; 121(16):7557-61.
    View in: PubMed
  76. Wagner TA, Zahn M, Grodzinsky AJ, Pascual-Leone A. Three-dimensional head model simulation of transcranial magnetic stimulation. IEEE Trans Biomed Eng. 2004 Sep; 51(9):1586-98.
    View in: PubMed
  77. Kisiday JD, Jin M, DiMicco MA, Kurz B, Grodzinsky AJ. Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds. J Biomech. 2004 May; 37(5):595-604.
    View in: PubMed
  78. Patwari P, Gaschen V, James IE, Berger E, Blake SM, Lark MW, Grodzinsky AJ, Hunziker EB. Ultrastructural quantification of cell death after injurious compression of bovine calf articular cartilage. Osteoarthritis Cartilage. 2004 Mar; 12(3):245-52.
    View in: PubMed
  79. Gouze JN, Gouze E, Palmer GD, Kaneto H, Ghivizzani SC, Grodzinsky AJ, Evans CH. Adenovirus-mediated gene transfer of glutamine: fructose-6-phosphate amidotransferase antagonizes the effects of interleukin-1beta on rat chondrocytes. Osteoarthritis Cartilage. 2004 Mar; 12(3):217-24.
    View in: PubMed
  80. DiMicco MA, Patwari P, Siparsky PN, Kumar S, Pratta MA, Lark MW, Kim YJ, Grodzinsky AJ. Mechanisms and kinetics of glycosaminoglycan release following in vitro cartilage injury. Arthritis Rheum. 2004 Mar; 50(3):840-8.
    View in: PubMed
  81. Fitzgerald JB, Jin M, Dean D, Wood DJ, Zheng MH, Grodzinsky AJ. Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. J Biol Chem. 2004 May 7; 279(19):19502-11.
    View in: PubMed
  82. Kurz B, Lemke A, Kehn M, Domm C, Patwari P, Frank EH, Grodzinsky AJ, Schünke M. Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression. Arthritis Rheum. 2004 Jan; 50(1):123-30.
    View in: PubMed
  83. Pufe T, Lemke A, Kurz B, Petersen W, Tillmann B, Grodzinsky AJ, Mentlein R. Mechanical overload induces VEGF in cartilage discs via hypoxia-inducible factor. Am J Pathol. 2004 Jan; 164(1):185-92.
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  84. Gouze JN, Stoddart MJ, Gouze E, Palmer GD, Ghivizzani SC, Grodzinsky AJ, Evans CH. In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors. Methods Mol Med. 2004; 100:147-64.
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  85. Kisiday J, Kerin A, Grodzinsky A. Mechanical testing of cell-material constructs: a review. Methods Mol Biol. 2004; 238:239-54.
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  86. Frank E, Evans R, Lee C, Treppo S, Spector M, Grodzinsky A. Quantitative electrical impedance analysis of cartilage degradation. Biorheology. 2004; 41(3-4):195-202.
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  87. Fanning PJ, Emkey G, Smith RJ, Grodzinsky AJ, Szasz N, Trippel SB. Mechanical regulation of mitogen-activated protein kinase signaling in articular cartilage. J Biol Chem. 2003 Dec 19; 278(51):50940-8.
    View in: PubMed
  88. Ng L, Grodzinsky AJ, Patwari P, Sandy J, Plaas A, Ortiz C. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol. 2003 Sep; 143(3):242-57.
    View in: PubMed
  89. Gouze JN, Gouze E, Palmer GD, Liew VS, Pascher A, Betz OB, Thornhill TS, Evans CH, Grodzinsky AJ, Ghivizzani SC. A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer. Arthritis Res Ther. 2003; 5(5):R301-9.
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  90. Garcia AM, Szasz N, Trippel SB, Morales TI, Grodzinsky AJ, Frank EH. Transport and binding of insulin-like growth factor I through articular cartilage. Arch Biochem Biophys. 2003 Jul 1; 415(1):69-79.
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  91. Jin M, Emkey GR, Siparsky P, Trippel SB, Grodzinsky AJ. Combined effects of dynamic tissue shear deformation and insulin-like growth factor I on chondrocyte biosynthesis in cartilage explants. Arch Biochem Biophys. 2003 Jun 15; 414(2):223-31.
    View in: PubMed
  92. Patwari P, Cook MN, DiMicco MA, Blake SM, James IE, Kumar S, Cole AA, Lark MW, Grodzinsky AJ. Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: interaction with exogenous cytokines. Arthritis Rheum. 2003 May; 48(5):1292-301.
    View in: PubMed
  93. Lee CR, Grodzinsky AJ, Hsu HP, Spector M. Effects of a cultured autologous chondrocyte-seeded type II collagen scaffold on the healing of a chondral defect in a canine model. J Orthop Res. 2003 Mar; 21(2):272-81.
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  94. Lee CR, Grodzinsky AJ, Spector M. Biosynthetic response of passaged chondrocytes in a type II collagen scaffold to mechanical compression. J Biomed Mater Res A. 2003 Mar 1; 64(3):560-9.
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  95. Lee CR, Grodzinsky AJ, Spector M. Modulation of the contractile and biosynthetic activity of chondrocytes seeded in collagen-glycosaminoglycan matrices. Tissue Eng. 2003 Feb; 9(1):27-36.
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  96. Lee JH, Kisiday J, Grodzinsky AJ. Tissue-engineered versus native cartilage: linkage between cellular mechano-transduction and biomechanical properties. Novartis Found Symp. 2003; 249:52-64; discussion 64-9, 170-4, 239-41.
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  97. Schaefer D, Martin I, Jundt G, Seidel J, Heberer M, Grodzinsky A, Bergin I, Vunjak-Novakovic G, Freed LE. Tissue-engineered composites for the repair of large osteochondral defects. Arthritis Rheum. 2002 Sep; 46(9):2524-34.
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  98. Quinn TM, Studer C, Grodzinsky AJ, Meister JJ. Preservation and analysis of nonequilibrium solute concentration distributions within mechanically compressed cartilage explants. J Biochem Biophys Methods. 2002 Jul 31; 52(2):83-95.
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  99. Kisiday J, Jin M, Kurz B, Hung H, Semino C, Zhang S, Grodzinsky AJ. Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15):9996-10001.
    View in: PubMed
  100. Quinn TM, Schmid P, Hunziker EB, Grodzinsky AJ. Proteoglycan deposition around chondrocytes in agarose culture: construction of a physical and biological interface for mechanotransduction in cartilage. Biorheology. 2002; 39(1-2):27-37.
    View in: PubMed
  101. Kerin A, Patwari P, Kuettner K, Cole A, Grodzinsky A. Molecular basis of osteoarthritis: biomechanical aspects. Cell Mol Life Sci. 2002 Jan; 59(1):27-35.
    View in: PubMed
  102. Lee CR, Grodzinsky AJ, Spector M. The effects of cross-linking of collagen-glycosaminoglycan scaffolds on compressive stiffness, chondrocyte-mediated contraction, proliferation and biosynthesis. Biomaterials. 2001 Dec; 22(23):3145-54.
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  103. Quinn TM, Dierickx P, Grodzinsky AJ. Glycosaminoglycan network geometry may contribute to anisotropic hydraulic permeability in cartilage under compression. J Biomech. 2001 Nov; 34(11):1483-90.
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  104. Kurz B, Jin M, Patwari P, Cheng DM, Lark MW, Grodzinsky AJ. Biosynthetic response and mechanical properties of articular cartilage after injurious compression. J Orthop Res. 2001 Nov; 19(6):1140-6.
    View in: PubMed
  105. Jin M, Frank EH, Quinn TM, Hunziker EB, Grodzinsky AJ. Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants. Arch Biochem Biophys. 2001 Nov 1; 395(1):41-8.
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  106. Patwari P, Fay J, Cook MN, Badger AM, Kerin AJ, Lark MW, Grodzinsky AJ. In vitro models for investigation of the effects of acute mechanical injury on cartilage. Clin Orthop Relat Res. 2001 Oct; (391 Suppl):S61-71.
    View in: PubMed
  107. Hu LT, Eskildsen MA, Masgala C, Steere AC, Arner EC, Pratta MA, Grodzinsky AJ, Loening A, Perides G. Host metalloproteinases in Lyme arthritis. Arthritis Rheum. 2001 Jun; 44(6):1401-10.
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  108. Griffith LG, Grodzinsky AJ. Advances in biomedical engineering. JAMA. 2001 Feb 7; 285(5):556-61.
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  109. Bonassar LJ, Grodzinsky AJ, Frank EH, Davila SG, Bhaktav NR, Trippel SB. The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I. J Orthop Res. 2001 Jan; 19(1):11-7.
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  110. Ragan PM, Chin VI, Hung HH, Masuda K, Thonar EJ, Arner EC, Grodzinsky AJ, Sandy JD. Chondrocyte extracellular matrix synthesis and turnover are influenced by static compression in a new alginate disk culture system. Arch Biochem Biophys. 2000 Nov 15; 383(2):256-64.
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  111. Frank EH, Jin M, Loening AM, Levenston ME, Grodzinsky AJ. A versatile shear and compression apparatus for mechanical stimulation of tissue culture explants. J Biomech. 2000 Nov; 33(11):1523-7.
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  112. Chen CT, McCabe RP, Grodzinsky AJ, Vanderby R. Transient and cyclic responses of strain-generated potential in rabbit patellar tendon are frequency and pH dependent. J Biomech Eng. 2000 Oct; 122(5):465-70.
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  113. Loening AM, James IE, Levenston ME, Badger AM, Frank EH, Kurz B, Nuttall ME, Hung HH, Blake SM, Grodzinsky AJ, Lark MW. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Arch Biochem Biophys. 2000 Sep 15; 381(2):205-12.
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  114. Treppo S, Koepp H, Quan EC, Cole AA, Kuettner KE, Grodzinsky AJ. Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs. J Orthop Res. 2000 Sep; 18(5):739-48.
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  115. Lee CR, Grodzinsky AJ, Hsu HP, Martin SD, Spector M. Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee. J Orthop Res. 2000 Sep; 18(5):790-9.
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  116. Bonassar LJ, Grodzinsky AJ, Srinivasan A, Davila SG, Trippel SB. Mechanical and physicochemical regulation of the action of insulin-like growth factor-I on articular cartilage. Arch Biochem Biophys. 2000 Jul 1; 379(1):57-63.
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  117. Netti PA, Berk DA, Swartz MA, Grodzinsky AJ, Jain RK. Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res. 2000 May 1; 60(9):2497-503.
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  118. Bhakta NR, Garcia AM, Frank EH, Grodzinsky AJ, Morales TI. The insulin-like growth factors (IGFs) I and II bind to articular cartilage via the IGF-binding proteins. J Biol Chem. 2000 Feb 25; 275(8):5860-6.
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  119. Patwari P, Kurz B, Sandy JD, Grodzinsky AJ. Mannosamine inhibits aggrecanase-mediated changes in the physical properties and biochemical composition of articular cartilage. Arch Biochem Biophys. 2000 Feb 1; 374(1):79-85.
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  120. Martin I, Obradovic B, Treppo S, Grodzinsky AJ, Langer R, Freed LE, Vunjak-Novakovic G. Modulation of the mechanical properties of tissue engineered cartilage. Biorheology. 2000; 37(1-2):141-7.
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  121. Grodzinsky AJ, Levenston ME, Jin M, Frank EH. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng. 2000; 2:691-713.
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  122. Swartz MA, Kaipainen A, Netti PA, Brekken C, Boucher Y, Grodzinsky AJ, Jain RK. Mechanics of interstitial-lymphatic fluid transport: theoretical foundation and experimental validation. J Biomech. 1999 Dec; 32(12):1297-307.
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  123. Ragan PM, Badger AM, Cook M, Chin VI, Gowen M, Grodzinsky AJ, Lark MW. Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration. J Orthop Res. 1999 Nov; 17(6):836-42.
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  124. Buckwalter JA, Grodzinsky AJ. Loading of healing bone, fibrous tissue, and muscle: implications for orthopaedic practice. J Am Acad Orthop Surg. 1999 Sep-Oct; 7(5):291-9.
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  125. Quinn TM, Maung AA, Grodzinsky AJ, Hunziker EB, Sandy JD. Physical and biological regulation of proteoglycan turnover around chondrocytes in cartilage explants. Implications for tissue degradation and repair. Ann N Y Acad Sci. 1999 Jun 30; 878:420-41.
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  126. Buschmann MD, Kim YJ, Wong M, Frank E, Hunziker EB, Grodzinsky AJ. Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow. Arch Biochem Biophys. 1999 Jun 1; 366(1):1-7.
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  127. Vunjak-Novakovic G, Martin I, Obradovic B, Treppo S, Grodzinsky AJ, Langer R, Freed LE. Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J Orthop Res. 1999 Jan; 17(1):130-8.
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  128. Garcia AM, Lark MW, Trippel SB, Grodzinsky AJ. Transport of tissue inhibitor of metalloproteinases-1 through cartilage: contributions of fluid flow and electrical migration. J Orthop Res. 1998 Nov; 16(6):734-42.
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  129. Quinn TM, Grodzinsky AJ, Hunziker EB, Sandy JD. Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explants. J Orthop Res. 1998 Jul; 16(4):490-9.
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  130. Quinn TM, Grodzinsky AJ, Buschmann MD, Kim YJ, Hunziker EB. Mechanical compression alters proteoglycan deposition and matrix deformation around individual cells in cartilage explants. J Cell Sci. 1998 Mar; 111 ( Pt 5):573-83.
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  131. Bonassar LJ, Sandy JD, Lark MW, Plaas AH, Frank EH, Grodzinsky AJ. Inhibition of cartilage degradation and changes in physical properties induced by IL-1beta and retinoic acid using matrix metalloproteinase inhibitors. Arch Biochem Biophys. 1997 Aug 15; 344(2):404-12.
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  132. Cheng GC, Briggs WH, Gerson DS, Libby P, Grodzinsky AJ, Gray ML, Lee RT. Mechanical strain tightly controls fibroblast growth factor-2 release from cultured human vascular smooth muscle cells. Circ Res. 1997 Jan; 80(1):28-36.
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  133. Garcia AM, Frank EH, Grimshaw PE, Grodzinsky AJ. Contributions of fluid convection and electrical migration to transport in cartilage: relevance to loading. Arch Biochem Biophys. 1996 Sep 15; 333(2):317-25.
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  134. Bonassar LJ, Stinn JL, Paguio CG, Frank EH, Moore VL, Lark MW, Sandy JD, Hollander AP, Poole AR, Grodzinsky AJ. Activation and inhibition of endogenous matrix metalloproteinases in articular cartilage: effects on composition and biophysical properties. Arch Biochem Biophys. 1996 Sep 15; 333(2):359-67.
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  135. Kim YJ, Grodzinsky AJ, Plaas AH. Compression of cartilage results in differential effects on biosynthetic pathways for aggrecan, link protein, and hyaluronan. Arch Biochem Biophys. 1996 Apr 15; 328(2):331-40.
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  136. Buschmann MD, Hunziker EB, Kim YJ, Grodzinsky AJ. Altered aggrecan synthesis correlates with cell and nucleus structure in statically compressed cartilage. J Cell Sci. 1996 Feb; 109 ( Pt 2):499-508.
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  137. Whale MD, Grodzinsky AJ, Johnson M. The effect of aging and pressure on the specific hydraulic conductivity of the aortic wall. Biorheology. 1996 Jan-Feb; 33(1):17-44.
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  138. Sah RL, Trippel SB, Grodzinsky AJ. Differential effects of serum, insulin-like growth factor-I, and fibroblast growth factor-2 on the maintenance of cartilage physical properties during long-term culture. J Orthop Res. 1996 Jan; 14(1):44-52.
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  139. Cheng GC, Libby P, Grodzinsky AJ, Lee RT. Induction of DNA synthesis by a single transient mechanical stimulus of human vascular smooth muscle cells. Role of fibroblast growth factor-2. Circulation. 1996 Jan 1; 93(1):99-105.
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  140. Lee E, Vaughan DE, Parikh SH, Grodzinsky AJ, Libby P, Lark MW, Lee RT. Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells. Circ Res. 1996 Jan; 78(1):44-9.
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  141. Lee E, Grodzinsky AJ, Libby P, Clinton SK, Lark MW, Lee RT. Human vascular smooth muscle cell-monocyte interactions and metalloproteinase secretion in culture. Arterioscler Thromb Vasc Biol. 1995 Dec; 15(12):2284-9.
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  142. Chang YH, Grodzinsky AJ, Wang DI. Augmentation of mass transfer through electrical means for hydrogel-entrapped Escherichia coli cultivation. Biotechnol Bioeng. 1995 Oct 20; 48(2):149-57.
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  143. Bonassar LJ, Jeffries KA, Paguio CG, Grodzinsky AJ. Cartilage degradation and associated changes in biochemical and electromechanical properties. Acta Orthop Scand Suppl. 1995 Oct; 266:38-44.
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  144. Kim YJ, Bonassar LJ, Grodzinsky AJ. The role of cartilage streaming potential, fluid flow and pressure in the stimulation of chondrocyte biosynthesis during dynamic compression. J Biomech. 1995 Sep; 28(9):1055-66.
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  145. Chang YH, Grodzinsky AJ, Wang DI. Nutrient enrichment and in-situ waste removal through electrical means for hybridoma cultures. Biotechnol Bioeng. 1995 Aug 5; 47(3):319-26.
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  146. Chang YH, Grodzinsky AJ, Wang DI. In-situ removal of ammonium and lactate through electrical means for hybridoma cultures. Biotechnol Bioeng. 1995 Aug 5; 47(3):308-18.
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  147. Sachs JR, Grodzinsky AJ. Electromechanical spectroscopy of cartilage using a surface probe with applied mechanical displacement. J Biomech. 1995 Aug; 28(8):963-76.
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  148. Mallein-Gerin F, Ruggiero F, Quinn TM, Bard F, Grodzinsky AJ, Olsen BR, van der Rest M. Analysis of collagen synthesis and assembly in culture by immortalized mouse chondrocytes in the presence or absence of alpha 1(IX) collagen chains. Exp Cell Res. 1995 Jul; 219(1):257-65.
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  149. Buschmann MD, Grodzinsky AJ. A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics. J Biomech Eng. 1995 May; 117(2):179-92.
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  150. Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci. 1995 Apr; 108 ( Pt 4):1497-508.
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  151. Bonassar LJ, Frank EH, Murray JC, Paguio CG, Moore VL, Lark MW, Sandy JD, Wu JJ, Eyre DR, Grodzinsky AJ. Changes in cartilage composition and physical properties due to stromelysin degradation. Arthritis Rheum. 1995 Feb; 38(2):173-83.
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  152. Berkenblit SI, Frank EH, Salant EP, Grodzinsky AJ. Nondestructive detection of cartilage degeneration using electromechanical surface spectroscopy. J Biomech Eng. 1994 Nov; 116(4):384-92.
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  153. Bonassar LJ, Paguio CG, Frank EH, Jeffries KA, Moore VL, Lark MW, Caldwell CG, Hagmann WK, Grodzinsky AJ. Effects of matrix metalloproteinases on cartilage biophysical properties in vitro and in vivo. Ann N Y Acad Sci. 1994 Sep 6; 732:439-43.
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  154. Kim YJ, Sah RL, Grodzinsky AJ, Plaas AH, Sandy JD. Mechanical regulation of cartilage biosynthetic behavior: physical stimuli. Arch Biochem Biophys. 1994 May 15; 311(1):1-12.
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  155. MacGinitie LA, Gluzband YA, Grodzinsky AJ. Electric field stimulation can increase protein synthesis in articular cartilage explants. J Orthop Res. 1994 Mar; 12(2):151-60.
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  156. Loree HM, Grodzinsky AJ, Park SY, Gibson LJ, Lee RT. Static circumferential tangential modulus of human atherosclerotic tissue. J Biomech. 1994 Feb; 27(2):195-204.
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  157. Sah RL, Chen AC, Grodzinsky AJ, Trippel SB. Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants. Arch Biochem Biophys. 1994 Jan; 308(1):137-47.
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  158. Basser PJ, Grodzinsky AJ. The Donnan model derived from microstructure. Biophys Chem. 1993 Feb; 46(1):57-68.
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  159. Edelman ER, Fiorino A, Grodzinsky A, Langer R. Mechanical deformation of polymer matrix controlled release devices modulates drug release. J Biomed Mater Res. 1992 Dec; 26(12):1619-31.
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  160. Buschmann MD, Gluzband YA, Grodzinsky AJ, Kimura JH, Hunziker EB. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J Orthop Res. 1992 Nov; 10(6):745-58.
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  161. Lee RT, Richardson SG, Loree HM, Grodzinsky AJ, Gharib SA, Schoen FJ, Pandian N. Prediction of mechanical properties of human atherosclerotic tissue by high-frequency intravascular ultrasound imaging. An in vitro study. Arterioscler Thromb. 1992 Jan; 12(1):1-5.
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  162. Lee RT, Grodzinsky AJ, Frank EH, Kamm RD, Schoen FJ. Structure-dependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques. Circulation. 1991 May; 83(5):1764-70.
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  163. Sah RL, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD. Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants. Arch Biochem Biophys. 1991 Apr; 286(1):20-9.
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  164. Sah RL, Grodzinsky AJ, Plaas AH, Sandy JD. Effects of tissue compression on the hyaluronate-binding properties of newly synthesized proteoglycans in cartilage explants. Biochem J. 1990 May 1; 267(3):803-8.
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  165. Gray ML, Pizzanelli AM, Lee RC, Grodzinsky AJ, Swann DA. Kinetics of the chondrocyte biosynthetic response to compressive load and release. Biochim Biophys Acta. 1989 Jun 27; 991(3):415-25.
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  166. Sah RL, Kim YJ, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res. 1989; 7(5):619-36.
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  167. Kim YJ, Sah RL, Doong JY, Grodzinsky AJ. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem. 1988 Oct; 174(1):168-76.
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  168. Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physiochemical determinants of the chondrocyte biosynthetic response. J Orthop Res. 1988; 6(6):777-92.
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  169. Valleton JM, Grodzinsky AJ, Selegny E. Theoretical study of mechano-chemical couplings in a compartmental enzyme system. I. Analytical treatment. Biophys Chem. 1987 Apr; 26(1):29-38.
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  170. Lavine LS, Grodzinsky AJ. Electrical stimulation of repair of bone. J Bone Joint Surg Am. 1987 Apr; 69(4):626-30.
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  171. Eisenberg SR, Grodzinsky AJ. The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. J Biomech Eng. 1987 Feb; 109(1):79-89.
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  172. Frank EH, Grodzinsky AJ, Koob TJ, Eyre DR. Streaming potentials: a sensitive index of enzymatic degradation in articular cartilage. J Orthop Res. 1987; 5(4):497-508.
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  173. Frank EH, Grodzinsky AJ. Cartilage electromechanics--I. Electrokinetic transduction and the effects of electrolyte pH and ionic strength. J Biomech. 1987; 20(6):615-27.
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  174. Frank EH, Grodzinsky AJ. Cartilage electromechanics--II. A continuum model of cartilage electrokinetics and correlation with experiments. J Biomech. 1987; 20(6):629-39.
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  175. Valleton JM, Grodzinsky AJ. Conductivity-mediated regulation in a compartmental enzyme system. Superactivation and conductance bistability. Biophys Chem. 1986 Aug; 24(3):277-84.
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  176. Eisenberg SR, Grodzinsky AJ. Swelling of articular cartilage and other connective tissues: electromechanochemical forces. J Orthop Res. 1985; 3(2):148-59.
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  177. Grodzinsky AJ. Electromechanical and physicochemical properties of connective tissue. Crit Rev Biomed Eng. 1983; 9(2):133-99.
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  178. Grodzinsky AJ, Hey LA. Skeletal tissue electromechanics & electrical stimulation of growth & remodeling. IEEE Eng Med Biol Mag. 1983; 2(4):18-22.
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  179. Hoch DH, Grodzinsky AJ, Koob TJ, Albert ML, Eyre DR. Early changes in material properties of rabbit articular cartilage after meniscectomy. J Orthop Res. 1983; 1(1):4-12.
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  180. Grodzinsky AJ, Chen TL, Newton DW. Physical characterization of electrosurgical coagulation. J Surg Res. 1982 Dec; 33(6):469-81.
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  181. Grodzinsky AJ, Roth V, Myers E, Grossman WD, Mow VC. The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension. J Biomech Eng. 1981 Nov; 103(4):221-31.
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  182. Lee RC, Frank EH, Grodzinsky AJ, Roylance DK. Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties. J Biomech Eng. 1981 Nov; 103(4):280-92.
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  183. Shoenfeld NA, Grodzinsky AJ. Contribution of electrodiffusion to the dynamics of electrically stimulated changes in mechanical properties of collagen membranes. Biopolymers. 1980 Feb; 19(2):241-62.
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  184. Grodzinsky AJ, Lipshitz H, Glimcher MJ. Electromechanical properties of articular cartilage during compression and stress relaxation. Nature. 1978 Oct 5; 275(5679):448-50.
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  185. Grodzinsky AJ, Melcher JR. Electromechanical transduction with charged polyelectrolyte membranes. IEEE Trans Biomed Eng. 1976 Nov; 23(6):421-33.
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  186. Picheny MA, Grodzinsky AJ. Letter: Method for measurement of charge in collagen and polyelectrolyte composite materials. Biopolymers. 1976 Sep; 15(9):1845-51.
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  187. Yannas IV, Grodzinsky AJ. Electromechanical energy conversion with collagen fibers in an aqueous medium. J Mechanochem Cell Motil. 1973 May; 2(1):113-25.
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