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Michael S.D. Agus, M.D.

TitleAssociate Professor of Pediatrics
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressChildrens Hospital
Main 11 South
300 Longwood Ave
Boston MA 02115
Phone617/355-5849
Fax888/883-9238

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Agus MS. Tight glycemic control in children--is the target in sight? N Engl J Med. 2014 Jan 9; 370(2):168-9.
    View in: PubMed
  2. Decourcey DD, Steil GM, Wypij D, Agus MS. Increasing use of hypertonic saline over mannitol in the treatment of symptomatic cerebral edema in pediatric diabetic ketoacidosis: an 11-year retrospective analysis of mortality*. Pediatr Crit Care Med. 2013 Sep; 14(7):694-700.
    View in: PubMed
  3. Hirshberg EL, Sward KA, Faustino EV, Nadkarni VM, Agus MS, Morris AH, Lacroix J. Clinical equipoise regarding glycemic control: a survey of pediatric intensivist perceptions. Pediatr Crit Care Med. 2013 Feb; 14(2):123-9.
    View in: PubMed
  4. Gaies MG, Langer M, Alexander J, Steil GM, Ware J, Wypij D, Laussen PC, Newburger JW, Goldberg CS, Pigula FA, Shukla AC, Duggan CP, Agus MS. Design and rationale of safe pediatric euglycemia after cardiac surgery: a randomized controlled trial of tight glycemic control after pediatric cardiac surgery. Pediatr Crit Care Med. 2013 Feb; 14(2):148-56.
    View in: PubMed
  5. Jacobi J, Bircher N, Krinsley J, Agus M, Braithwaite SS, Deutschman C, Freire AX, Geehan D, Kohl B, Nasraway SA, Rigby M, Sands K, Schallom L, Taylor B, Umpierrez G, Mazuski J, Schunemann H. Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients. Crit Care Med. 2012 Dec; 40(12):3251-76.
    View in: PubMed
  6. Wong J, Agus MS, Steil GM. Cardiac parameters in children recovered from acute illness as measured by electrical cardiometry and comparisons to the literature. J Clin Monit Comput. 2013 Feb; 27(1):81-91.
    View in: PubMed
  7. Dauber A, Corcia L, Safer J, Agus MS, Einis S, Steil GM. Closed-Loop Insulin Therapy Improves Glycemic Control in Children Aged <7 Years: A randomized controlled trial. Diabetes Care. 2013 Feb; 36(2):222-7.
    View in: PubMed
  8. Agus MS, Steil GM, Wypij D, Costello JM, Laussen PC, Langer M, Alexander JL, Scoppettuolo LA, Pigula FA, Charpie JR, Ohye RG, Gaies MG. Tight glycemic control versus standard care after pediatric cardiac surgery. N Engl J Med. 2012 Sep 27; 367(13):1208-19.
    View in: PubMed
  9. Steil GM, Langer M, Jaeger K, Alexander J, Gaies M, Agus MS. Value of continuous glucose monitoring for minimizing severe hypoglycemia during tight glycemic control. Pediatr Crit Care Med. 2011 Nov; 12(6):643-8.
    View in: PubMed
  10. Steil GM, Eckstein OS, Caplow J, Agus MS, Walsh BK, Wong J. Non-invasive cardiac output and oxygen delivery measurement in an infant with critical anemia. J Clin Monit Comput. 2011 Apr; 25(2):113-9.
    View in: PubMed
  11. Yu HY, Agus M, Kellogg MD. Clinical utility of Abbott Precision Xceed Pro® ketone meter in diabetic patients. Pediatr Diabetes. 2011 Nov; 12(7):649-55.
    View in: PubMed
  12. Steil GM, Alexander J, Papas A, Monica L, Modi BP, Piper H, Jaksic T, Gottlieb R, Agus MS. Use of a continuous glucose sensor in an extracorporeal life support circuit. J Diabetes Sci Technol. 2011 Jan; 5(1):93-8.
    View in: PubMed
  13. Agus MS, Alexander JL, Wolfsdorf JI. Utility of immediate hemoglobin A1c in children with type I diabetes mellitus. Pediatr Diabetes. 2010 Nov; 11(7):450-4.
    View in: PubMed
  14. Weiss SL, Alexander J, Agus MS. Extreme stress hyperglycemia during acute illness in a pediatric emergency department. Pediatr Emerg Care. 2010 Sep; 26(9):626-32.
    View in: PubMed
  15. Agus MSD. Endocrine emergencies. Fleisher GR, Ludwig S, editors. Textbook of Pediatric Emergency Medicine. 2009.
  16. Shih JL, Agus MS. Thyroid function in the critically ill newborn and child. Curr Opin Pediatr. 2009 Aug; 21(4):536-40.
    View in: PubMed
  17. Mallory LA, Shaw JG, Burgess SL, Estrella E, Nurko S, Burpee TM, Agus MS, Darras BT, Kunkel LM, Kang PB. Congenital myasthenic syndrome with episodic apnea. Pediatr Neurol. 2009 Jul; 41(1):42-5.
    View in: PubMed
  18. Agus MS, Hirshberg EL. Pediatrics: Intensive insulin therapy in critically ill children. Nat Rev Endocrinol. 2009 Jul; 5(7):360-2.
    View in: PubMed
  19. Mallory LA, Shaw JG, Burgess SL,Estrella E, Nurko S, Burpee TM, Agus MS, Darras BT, Kunkel LM, Kang PB. Choline acetyltransferase deficiency causing congenital myasthenic syndrome with episodic apnea. Pediatr Neurol. 2009; 41:42-45.
  20. Steil GM, Agus MSD. Critical illness hyperglycemia: is failure of the beta-cell to meet extreme insulin demand indicative of dysfunction?. Critical Care. 2009; 13:129.
  21. Steil GM, Agus MS. Critical illness hyperglycemia: is failure of the beta-cell to meet extreme insulin demand indicative of dysfunction? Crit Care. 2009; 13(2):129.
    View in: PubMed
  22. Moses JM, Alexander JL, Agus MS. The correlation and level of agreement between end-tidal and blood gas pCO2 in children with respiratory distress: a retrospective analysis. BMC Pediatr. 2009; 9:20.
    View in: PubMed
  23. Steil GM, Deiss D, Shih J, Buckingham B, Weinzimer S, Agus MSD. ICU Insulin delivery algorithms: Why so many? How to choose?. J Diab Sci Tech. 2009; 3(1):125-140.
  24. Polito A, Thiagarajan RR, Laussen PC, Gauvreau K, Agus MS, Scheurer MA, Pigula FA, Costello JM. Association between intraoperative and early postoperative glucose levels and adverse outcomes after complex congenital heart surgery. Circulation. 2008 Nov 25; 118(22):2235-42.
    View in: PubMed
  25. Agus MS, Javid PJ, Piper HG, Wypij D, Duggan CP, Ryan DP, Jaksic T. The effect of insulin infusion upon protein metabolism in neonates on extracorporeal life support. Ann Surg. 2006 Oct; 244(4):536-44.
    View in: PubMed
  26. Langer M, Modi, BP, Alexander JA, Jaksic T, Agus M. Continuous Glucose Monitoring in Pediatric Patients on Extracorporeal Life Support. American Academy of Pediatrics. 2006.
  27. Piper HG, Alexander JL, Shukla A, Pigula F, Costello JM, Laussen PC, Jaksic T, Agus MS. Real-time continuous glucose monitoring in pediatric patients during and after cardiac surgery. Pediatrics. 2006 Sep; 118(3):1176-84.
    View in: PubMed
  28. Agus MS, Alexander JL, Mantell PA. Continuous non-invasive end-tidal CO2 monitoring in pediatric inpatients with diabetic ketoacidosis. Pediatr Diabetes. 2006 Aug; 7(4):196-200.
    View in: PubMed
  29. Langer M, Modi BP, Agus M. Adrenal insufficiency in the critically ill neonate and child. Curr Opin Pediatr. 2006 Aug; 18(4):448-53.
    View in: PubMed
  30. Agus, MSD, Jaksic, T. Nutritional Support of the Critically Ill Child. Wheeler DS, Wong HR, Shanley TP, editors. Pediatric Critical Care Medicine: Basic Science and Clinical Evidence. 2005.
  31. Agus MSD, Alexander JA, Wolfsdorf JI. Benefits of immediate hemoglobin A1c results in pediatric type 1 diabetes patients. European Society of Pediatric Endocrinology and Lawson Wilkins Pediatric Endocrine Society. 2005.
  32. Agus MSD, Piper HG, Alexander JA, Shukla A, Costello J, Pigula F, Jaksic T, Laussen P. Continuous glucose monitoring in pediatric cardiac surgery patients. European Society of Pediatric Endocrinology and Lawson Wilkins Pediatric Endocrine Society. 2005.
  33. Agus MSD, Alexander JA, Wolfsdorf JI. Benefits of immediate hemoglobin A1c results in pediatric type 1 diabetes patients. Hormone Research. 2005; 64(S1).
  34. Agus MS, Wolfsdorf JI. Diabetic ketoacidosis in children. Pediatr Clin North Am. 2005 Aug; 52(4):1147-63, ix.
    View in: PubMed
  35. Agus MSD, Piper HG, Javid PJ, Ryan DR, Duggan CP, Jaksic T. The effects of insulin on protein metabolism in critically ill neonates. Endocrine Society. 2005.
  36. Javid PJ, Halwick DR, Betit P, Thompson JE, Long K, Zhang Y, Jaksic T, Agus MS. The first use of live continuous glucose monitoring in patients on extracorporeal life support. Diabetes Technol Ther. 2005 Jun; 7(3):431-9.
    View in: PubMed
  37. Agus M. One step forward: an advance in understanding of adrenal insufficiency in the pediatric critically ill. Crit Care Med. 2005 Apr; 33(4):911-2.
    View in: PubMed
  38. Agus MSD. Endocrine emergencies. Fleisher GR, Ludwig S, editors. Textbook of Pediatric Emergency Medicine. 2004.
  39. Agus MSD, Lindheim J. Clowning in the pediatric intensive care unit. Lindheim J, editor. The Art and Joy of Hospital Clowning: The Jeannie Lindheim Hospital Clown Training Process. 2004.
  40. Javid PJ, Haight R, Long K, Zhang Y, Jaksic T, Agus MSD. The first use of live continuous glucose monitoring in critically ill neonates. American Diabetes Association. 2004.
  41. Agus MSD, Alexander JA, Mantell P. Continuous non-invasive CO2 monitoring in pediatric inpatients with diabetic ketoacidosis. American Diabetes Association. 2004.
  42. Agus MS, Javid PJ, Ryan DP, Jaksic T. Intravenous insulin decreases protein breakdown in infants on extracorporeal membrane oxygenation. J Pediatr Surg. 2004 Jun; 39(6):839-44; discussion 839-44.
    View in: PubMed
  43. Agus MS, Jaksic T. Critically low hormone and catecholamine concentrations in the primed extracorporeal life support circuit. ASAIO J. 2004 Jan-Feb; 50(1):65-7.
    View in: PubMed
  44. Warren HS, Jr, Gonzalez RG, Tian D. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 38-2003. A 12-year-old girl with fever and coma. New England Journal of Medicine. 2003; 349(24):2341-9.
  45. Javid PJ, Agus MSD, Ryan DP, Jaksic T. Intravenous Insulin Improves Protein Breakdown in Infants on Extracorporeal Membrane Oxygenation. Journal of the American College of Surgeons. 2003; 197(3):S48.
  46. Javid PJ, Halwick D, Jaksic T, Long K, Zhang Y, Agus MSD. Continuous glucose monitoring in an extracorporeal circuit. ECMO & Advanced Therapies for Respiratory Failure. 2003.
  47. Halwick DR, Betit P, Thompson JE, Javid PJ, Long KJ, Zhang Y, Agus MSD. Technical evaluation of a glucose and oxygen sensor in an extracorporeal circuit. ECMO & Advanced Therapies for Respiratory Failure. 2003.
  48. Agus MSD. Continuous analyte monitor and method of using same. 2002.
  49. Agus MS, Jaksic T. Nutritional support of the critically ill child. Curr Opin Pediatr. 2002 Aug; 14(4):470-81.
    View in: PubMed
  50. Agus MSD, Ryan DP, Jaksic T. Effect of hyperinsulinemic clamp on protein catabolism in critically ill neonates. Lawson Wilkins Pediatric Endocrine Society at Society for Pediatric Research. 2002.
  51. Agus MS, Agus ZS. Cardiovascular actions of magnesium. Crit Care Clin. 2001 Jan; 17(1):175-86.
    View in: PubMed
  52. Agus, MSD. The hormonal response to critical illness. Radovick S, MacGillivray MH, editors. Trends in Pediatric Endocrinology. 2001.
  53. Agus MS, Swain JF, Larson CL, Eckert EA, Ludwig DS. Dietary composition and physiologic adaptations to energy restriction. Am J Clin Nutr. 2000 Apr; 71(4):901-7.
    View in: PubMed
  54. Katz LE, Liu F, Baker B, Agus MS, Nunn SE, Hintz RL, Cohen P. The effect of growth hormone treatment on the insulin-like growth factor axis in a child with nonislet cell tumor hypoglycemia. J Clin Endocrinol Metab. 1996 Mar; 81(3):1141-6.
    View in: PubMed
  55. Agus MS, Katz LE, Satin-Smith M, Meadows AT, Hintz RL, Cohen P. Non-islet-cell tumor associated with hypoglycemia in a child: successful long-term therapy with growth hormone. J Pediatr. 1995 Sep; 127(3):403-7.
    View in: PubMed
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