Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Martha L. Gray, PH.D.

TitleMember of the Affiliated Faculty of the Harvard-MIT Division of Health Sciences and Technology
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology
AddressMass Institute Of Technology
HST Division, Bldg. E25-519
77 Massachusetts Ave
Cambridge MA 02139
Phone617/253-4378
Fax617/253-7498

 Mentoring 
 completed student projects
Assessment of Repair of Mechanically Loaded, Damaged Cartilage
Summer, 06/17/05 - 08/31/05

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Burstein D, Gray M, Mosher T, Dardzinski B. Measures of molecular composition and structure in osteoarthritis. Radiol Clin North Am. 2009 Jul; 47(4):675-86.
    View in: PubMed
  2. Jessel RH, Zurakowski D, Zilkens C, Burstein D, Gray ML, Kim YJ. Radiographic and patient factors associated with pre-radiographic osteoarthritis in hip dysplasia. J Bone Joint Surg Am. 2009 May; 91(5):1120-9.
    View in: PubMed
  3. Dugar A, Farley ML, Wang AL, Goldring MB, Goldring SR, Swaim BH, Bierbaum BE, Burstein D, Gray ML. The effect of paraformaldehyde fixation on the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) measurement. J Orthop Res. 2009 Apr; 27(4):536-9.
    View in: PubMed
  4. Stubbs AJ, Gray ML, Pearle AD. Section I: Setting the stage. J Bone Joint Surg Am. 2009 Feb; 91 Suppl 1:3.
    View in: PubMed
  5. Gray ML. Toward imaging biomarkers for glycosaminoglycans. J Bone Joint Surg Am. 2009 Feb; 91 Suppl 1:44-9.
    View in: PubMed
  6. Gray ML, Pearle AD. Advanced imaging and computer-assisted surgery of the knee and hip. Introduction. J Bone Joint Surg Am. 2009 Feb; 91 Suppl 1:1-2.
    View in: PubMed
  7. Augst A, Marolt D, Freed LE, Vepari C, Meinel L, Farley M, Fajardo R, Patel N, Gray M, Kaplan DL, Vunjak-Novakovic G. Effects of chondrogenic and osteogenic regulatory factors on composite constructs grown using human mesenchymal stem cells, silk scaffolds and bioreactors. J R Soc Interface. 2008 Aug 6; 5(25):929-39.
    View in: PubMed
  8. Goodwin JL, Farley ML, Swaim B, Goldring SR, Goldring MB, Bierbaum BE, Gray ML. Dual proline labeling protocol for individual "baseline" and "response" biosynthesis measurements in human articular cartilage. Osteoarthritis Cartilage. 2008 Oct; 16(10):1263-6.
    View in: PubMed
  9. Gray ML, Burstein D, Kim YJ, Maroudas A. 2007 Elizabeth Winston Lanier Award Winner. Magnetic resonance imaging of cartilage glycosaminoglycan: basic principles, imaging technique, and clinical applications. J Orthop Res. 2008 Mar; 26(3):281-91.
    View in: PubMed
  10. Williams A, Mikulis B, Krishnan N, Gray M, McKenzie C, Burstein D. Suitability of T(1Gd) as the dGEMRIC index at 1.5T and 3.0T. Magn Reson Med. 2007 Oct; 58(4):830-4.
    View in: PubMed
  11. Baldassarri M, Goodwin JS, Farley ML, Bierbaum BE, Goldring SR, Goldring MB, Burstein D, Gray ML. Relationship between cartilage stiffness and dGEMRIC index: correlation and prediction. J Orthop Res. 2007 Jul; 25(7):904-12.
    View in: PubMed
  12. Freed LE, Guilak F, Guo XE, Gray ML, Tranquillo R, Holmes JW, Radisic M, Sefton MV, Kaplan D, Vunjak-Novakovic G. Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling. Tissue Eng. 2006 Dec; 12(12):3285-305.
    View in: PubMed
  13. Deng X, Farley M, Nieminen MT, Gray M, Burstein D. Diffusion tensor imaging of native and degenerated human articular cartilage. Magn Reson Imaging. 2007 Feb; 25(2):168-71.
    View in: PubMed
  14. Burstein D, Gray ML. Is MRI fulfilling its promise for molecular imaging of cartilage in arthritis? Osteoarthritis Cartilage. 2006 Nov; 14(11):1087-90.
    View in: PubMed
  15. Marolt D, Augst A, Freed LE, Vepari C, Fajardo R, Patel N, Gray M, Farley M, Kaplan D, Vunjak-Novakovic G. Bone and cartilage tissue constructs grown using human bone marrow stromal cells, silk scaffolds and rotating bioreactors. Biomaterials. 2006 Dec; 27(36):6138-49.
    View in: PubMed
  16. Samosky JT, Burstein D, Eric Grimson W, Howe R, Martin S, Gray ML. Spatially-localized correlation of dGEMRIC-measured GAG distribution and mechanical stiffness in the human tibial plateau. J Orthop Res. 2005 Jan; 23(1):93-101.
    View in: PubMed
  17. Gray ML, Burstein D. Molecular (and functional) imaging of articular cartilage. J Musculoskelet Neuronal Interact. 2004 Dec; 4(4):365-8.
    View in: PubMed
  18. Gray ML, Eckstein F, Peterfy C, Dahlberg L, Kim YJ, Sorensen AG. Toward imaging biomarkers for osteoarthritis. Clin Orthop Relat Res. 2004 Oct; (427 Suppl):S175-81.
    View in: PubMed
  19. Menezes NM, Gray ML, Hartke JR, Burstein D. T2 and T1rho MRI in articular cartilage systems. Magn Reson Med. 2004 Mar; 51(3):503-9.
    View in: PubMed
  20. Seidel JO, Pei M, Gray ML, Langer R, Freed LE, Vunjak-Novakovic G. Long-term culture of tissue engineered cartilage in a perfused chamber with mechanical stimulation. Biorheology. 2004; 41(3-4):445-58.
    View in: PubMed
  21. Kim YJ, Jaramillo D, Millis MB, Gray ML, Burstein D. Assessment of early osteoarthritis in hip dysplasia with delayed gadolinium-enhanced magnetic resonance imaging of cartilage. J Bone Joint Surg Am. 2003 Oct; 85-A(10):1987-92.
    View in: PubMed
  22. Gold GE, McCauley TR, Gray ML, Disler DG. What's new in cartilage? Radiographics. 2003 Sep-Oct; 23(5):1227-42.
    View in: PubMed
  23. Greenberg JE, Delgutte B, Gray ML. Hands-on learning in biomedical signal processing. IEEE Eng Med Biol Mag. 2003 Jul-Aug; 22(4):71-9.
    View in: PubMed
  24. Williams A, Oppenheimer RA, Gray ML, Burstein D. Differential recovery of glycosaminoglycan after IL-1-induced degradation of bovine articular cartilage depends on degree of degradation. Arthritis Res Ther. 2003; 5(2):R97-105.
    View in: PubMed
  25. Burstein D, Gray M. New MRI techniques for imaging cartilage. J Bone Joint Surg Am. 2003; 85-A Suppl 2:70-7.
    View in: PubMed
  26. Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, Gold M, Weiss A, Stull JT, Berridge MJ, Cantley LC, Catterall WA, Coughlin SR, Olson EN, Smith TF, Brugge JS, Botstein D, Dixon JE, Hunter T, Lefkowitz RJ, Pawson AJ, Sternberg PW, Varmus H, Subramaniam S, Sinkovits RS, Li J, Mock D, Ning Y, Saunders B, Sternweis PC, Hilgemann D, Scheuermann RH, DeCamp D, Hsueh R, Lin KM, Ni Y, Seaman WE, Simpson PC, O'Connell TD, Roach T, Simon MI, Choi S, Eversole-Cire P, Fraser I, Mumby MC, Zhao Y, Brekken D, Shu H, Meyer T, Chandy G, Heo WD, Liou J, O'Rourke N, Verghese M, Mumby SM, Han H, Brown HA, Forrester JS, Ivanova P, Milne SB, Casey PJ, Harden TK, Arkin AP, Doyle J, Gray ML, Meyer T, Michnick S, Schmidt MA, Toner M, Tsien RY, Natarajan M, Ranganathan R, Sambrano GR. Overview of the Alliance for Cellular Signaling. Nature. 2002 Dec 12; 420(6916):703-6.
    View in: PubMed
  27. Gillis A, Gray M, Burstein D. Relaxivity and diffusion of gadolinium agents in cartilage. Magn Reson Med. 2002 Dec; 48(6):1068-71.
    View in: PubMed
  28. Voldman J, Gray ML, Toner M, Schmidt MA. A microfabrication-based dynamic array cytometer. Anal Chem. 2002 Aug 15; 74(16):3984-90.
    View in: PubMed
  29. Gray ML, Bonventre JV. Training PhD researchers to translate science to clinical medicine: closing the gap from the other side. Nat Med. 2002 May; 8(5):433-6.
    View in: PubMed
  30. Gillis A, Bashir A, McKeon B, Scheller A, Gray ML, Burstein D. Magnetic resonance imaging of relative glycosaminoglycan distribution in patients with autologous chondrocyte transplants. Invest Radiol. 2001 Dec; 36(12):743-8.
    View in: PubMed
  31. Gray ML, Burstein D, Xia Y. Biochemical (and functional) imaging of articular cartilage. Semin Musculoskelet Radiol. 2001 Dec; 5(4):329-43.
    View in: PubMed
  32. Burstein D, Velyvis J, Scott KT, Stock KW, Kim YJ, Jaramillo D, Boutin RD, Gray ML. Protocol issues for delayed Gd(DTPA)(2-)-enhanced MRI (dGEMRIC) for clinical evaluation of articular cartilage. Magn Reson Med. 2001 Jan; 45(1):36-41.
    View in: PubMed
  33. Voldman J, Braff RA, Toner M, Gray ML, Schmidt MA. Holding forces of single-particle dielectrophoretic traps. Biophys J. 2001 Jan; 80(1):531-41.
    View in: PubMed
  34. Burstein D, Bashir A, Gray ML. MRI techniques in early stages of cartilage disease. Invest Radiol. 2000 Oct; 35(10):622-38.
    View in: PubMed
  35. Allen RG, Burstein D, Gray ML. Monitoring glycosaminoglycan replenishment in cartilage explants with gadolinium-enhanced magnetic resonance imaging. J Orthop Res. 1999 May; 17(3):430-6.
    View in: PubMed
  36. Bashir A, Gray ML, Hartke J, Burstein D. Nondestructive imaging of human cartilage glycosaminoglycan concentration by MRI. Magn Reson Med. 1999 May; 41(5):857-65.
    View in: PubMed
  37. Voldman J, Gray ML, Schmidt MA. Microfabrication in biology and medicine. Annu Rev Biomed Eng. 1999; 1:401-25.
    View in: PubMed
  38. Meazzini MC, Toma CD, Schaffer JL, Gray ML, Gerstenfeld LC. Osteoblast cytoskeletal modulation in response to mechanical strain in vitro. J Orthop Res. 1998 Mar; 16(2):170-80.
    View in: PubMed
  39. Bashir A, Gray ML, Boutin RD, Burstein D. Glycosaminoglycan in articular cartilage: in vivo assessment with delayed Gd(DTPA)(2-)-enhanced MR imaging. Radiology. 1997 Nov; 205(2):551-8.
    View in: PubMed
  40. Bashir A, Gray ML, Burstein D. Gd-DTPA2- as a measure of cartilage degradation. Magn Reson Med. 1996 Nov; 36(5):665-73.
    View in: PubMed
  41. Boustany NN, Gray ML, Black AC, Hunziker EB. Correlation between synthetic activity and glycosaminoglycan concentration in epiphyseal cartilage raises questions about the regulatory role of interstitial pH. J Orthop Res. 1995 Sep; 13(5):733-9.
    View in: PubMed
  42. Gray ML, Burstein D, Lesperance LM, Gehrke L. Magnetization transfer in cartilage and its constituent macromolecules. Magn Reson Med. 1995 Sep; 34(3):319-25.
    View in: PubMed
  43. Boustany NN, Gray ML, Black AC, Hunziker EB. Time-dependent changes in the response of cartilage to static compression suggest interstitial pH is not the only signaling mechanism. J Orthop Res. 1995 Sep; 13(5):740-50.
    View in: PubMed
  44. Garcia AM, Gray ML. Dimensional growth and extracellular matrix accumulation by neonatal rat mandibular condyles in long-term culture. J Orthop Res. 1995 Mar; 13(2):208-19.
    View in: PubMed
  45. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med. 1994 Jul; 32(1):66-76.
    View in: PubMed
  46. GarcĂ­a AM, Black AC, Gray ML. Effects of physicochemical factors on the growth of mandibular condyles in vitro. Calcif Tissue Int. 1994 Jun; 54(6):499-504.
    View in: PubMed
  47. Burstein D, Gray ML, Hartman AL, Gipe R, Foy BD. Diffusion of small solutes in cartilage as measured by nuclear magnetic resonance (NMR) spectroscopy and imaging. J Orthop Res. 1993 Jul; 11(4):465-78.
    View in: PubMed
  48. Lesperance LM, Gray ML, Burstein D. Determination of fixed charge density in cartilage using nuclear magnetic resonance. J Orthop Res. 1992 Jan; 10(1):1-13.
    View in: PubMed
  49. Gray ML, Pizzanelli AM, Lee RC, Grodzinsky AJ, Swann DA. Kinetics of the chondrocyte biosynthetic response to compressive load and release. Biochim Biophys Acta. 1989 Jun 27; 991(3):415-25.
    View in: PubMed
  50. Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physiochemical determinants of the chondrocyte biosynthetic response. J Orthop Res. 1988; 6(6):777-92.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Gray's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_