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Amal Ali Rahmeh, Ph.D.

TitleResearch Fellow in Microbiology and Immunobiology (INT)
InstitutionHarvard Medical School
DepartmentMicrobiology and Immunobiology
AddressHarvard Medical School
Microbiology and Immunob. NRB 940
77 Avenue Louis Pasteur
Boston MA 02115
Phone617/432-1927

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Morin B, Kranzusch PJ, Rahmeh AA, Whelan SP. The polymerase of negative-stranded RNA viruses. Curr Opin Virol. 2013 Apr; 3(2):103-10.
    View in: PubMed
  2. Rahmeh AA, Morin B, Schenk AD, Liang B, Heinrich BS, Brusic V, Walz T, Whelan SP. Critical phosphoprotein elements that regulate polymerase architecture and function in vesicular stomatitis virus. Proc Natl Acad Sci U S A. 2012 Sep 4; 109(36):14628-33.
    View in: PubMed
  3. Heinrich BS, Morin B, Rahmeh AA, Whelan SP. Structural properties of the C terminus of vesicular stomatitis virus N protein dictate N-RNA complex assembly, encapsidation, and RNA synthesis. J Virol. 2012 Aug; 86(16):8720-9.
    View in: PubMed
  4. Morin B, Rahmeh AA, Whelan SP. Mechanism of RNA synthesis initiation by the vesicular stomatitis virus polymerase. EMBO J. 2012 Mar 7; 31(5):1320-9.
    View in: PubMed
  5. Rahmeh AA, Zhou Y, Xie B, Li H, Lee EY, Lee MY. Phosphorylation of the p68 subunit of Pol d acts as a molecular switch to regulate its interaction with PCNA. Biochemistry. 2012 Jan 10; 51(1):416-24.
    View in: PubMed
  6. Tekes G, Rahmeh AA, Whelan SP. A freeze frame view of vesicular stomatitis virus transcription defines a minimal length of RNA for 5' processing. PLoS Pathog. 2011 Jun; 7(6):e1002073.
    View in: PubMed
  7. Rahmeh AA, Schenk AD, Danek EI, Kranzusch PJ, Liang B, Walz T, Whelan SP. Molecular architecture of the vesicular stomatitis virus RNA polymerase. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):20075-80.
    View in: PubMed
  8. Kranzusch PJ, Schenk AD, Rahmeh AA, Radoshitzky SR, Bavari S, Walz T, Whelan SP. Assembly of a functional Machupo virus polymerase complex. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):20069-74.
    View in: PubMed
  9. Heinrich BS, Cureton DK, Rahmeh AA, Whelan SP. Protein expression redirects vesicular stomatitis virus RNA synthesis to cytoplasmic inclusions. PLoS Pathog. 2010; 6(6):e1000958.
    View in: PubMed
  10. Rahmeh AA, Li J, Kranzusch PJ, Whelan SP. Ribose 2'-O methylation of the vesicular stomatitis virus mRNA cap precedes and facilitates subsequent guanine-N-7 methylation by the large polymerase protein. J Virol. 2009 Nov; 83(21):11043-50.
    View in: PubMed
  11. Li J, Rahmeh A, Brusic V, Whelan SP. Opposing effects of inhibiting cap addition and cap methylation on polyadenylation during vesicular stomatitis virus mRNA synthesis. J Virol. 2009 Feb; 83(4):1930-40.
    View in: PubMed
  12. Gao Y, Zhou Y, Xie B, Zhang S, Rahmeh A, Huang HS, Lee MY, Lee EY. Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit. Biochemistry. 2008 Oct 28; 47(43):11367-76.
    View in: PubMed
  13. Mikati MA, Zeinieh M, Habib RA, El Hokayem J, Rahmeh A, El Sabban M, Usta J, Dbaibo G. Changes in sphingomyelinases, ceramide, Bax, Bcl(2), and caspase-3 during and after experimental status epilepticus. Epilepsy Res. 2008 Oct; 81(2-3):161-6.
    View in: PubMed
  14. Mikati MA, Rizk E, El Dada S, Zeinieh M, Kurdi R, El Hokayem J, Rahmeh A, Koubeissi M, Kobeissi M, Azzam D, Usta J, El Sabban M, Dbaibo G. Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms. Brain Dev. 2008 Sep; 30(8):513-9.
    View in: PubMed
  15. Li J, Rahmeh A, Morelli M, Whelan SP. A conserved motif in region v of the large polymerase proteins of nonsegmented negative-sense RNA viruses that is essential for mRNA capping. J Virol. 2008 Jan; 82(2):775-84.
    View in: PubMed
  16. Rytkönen AK, Vaara M, Nethanel T, Kaufmann G, Sormunen R, Läärä E, Nasheuer HP, Rahmeh A, Lee MY, Syväoja JE, Pospiech H. Distinctive activities of DNA polymerases during human DNA replication. FEBS J. 2006 Jul; 273(13):2984-3001.
    View in: PubMed
  17. Li H, Xie B, Zhou Y, Rahmeh A, Trusa S, Zhang S, Gao Y, Lee EY, Lee MY. Functional roles of p12, the fourth subunit of human DNA polymerase delta. J Biol Chem. 2006 May 26; 281(21):14748-55.
    View in: PubMed
  18. Li H, Xie B, Rahmeh A, Zhou Y, Lee MY. Direct interaction of p21 with p50, the small subunit of human DNA polymerase delta. Cell Cycle. 2006 Feb; 5(4):428-36.
    View in: PubMed
  19. Xie B, Li H, Wang Q, Xie S, Rahmeh A, Dai W, Lee MY. Further characterization of human DNA polymerase delta interacting protein 38. J Biol Chem. 2005 Jun 10; 280(23):22375-84.
    View in: PubMed
  20. Mikati MA, Kurdit RM, Rahmeh AA, Farhat F, Abu Rialy S, Lteif L, Francis E, Geha G, Maraashli W. Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats. Brain Inj. 2004 Dec; 18(12):1229-41.
    View in: PubMed
  21. Xie B, Mazloum N, Liu L, Rahmeh A, Li H, Lee MY. Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme. Biochemistry. 2002 Nov 5; 41(44):13133-42.
    View in: PubMed
  22. Mikati MA, Werner S, Gatt A, Liu Z, Rahmeh AA, Rachid RA, Stafstrom CE, Holmes GL. Consequences of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor blockade during status epilepticus in the developing brain. Brain Res Dev Brain Res. 1999 Mar 12; 113(1-2):139-42.
    View in: PubMed
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