David J. Friedman, M.D.
|Title||Assistant Professor of Medicine|
|Institution||Beth Israel Deaconess Medical Center|
|Address||Beth Israel Deaconess Medical Center|
99 Brookline Ave
Boston MA 02215
||Harvard Medical School Class of 2002 Housestaff Teaching Award|
||Harvard Medical School Class of 2003 Housestaff Teaching Award|
||Excellence in Tutoring Award|
||Type 1 Diabetes Ideation Award|
||Clinical Scientist Development Award|
Available: 10/15/12, Expires: 06/30/14
African Americans develop kidney failure at rates 4-5 times higher than Caucasian Americans. We found genetic variants in a gene called APOL1 that account for most of this risk difference. These genetic disease-causing variants are amongst the most powerful every discovered, but we know almost nothing about the underlying mechanisms. We are working to understand the role of the ApoL1 protein in the kidney and why the risk variants cause kidney disease. Potential projects range from human genetics/genomics to mechanistic studies in cell and molecular biology.
This opportunity would be funded by a fellowship from the Doris Duke Charitable Foundation, a major sponsor of the project. Please contact David Friedman, M.D., for more information.
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