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Barr TP, Albrecht PJ, Hou Q, Mongin AA, Strichartz GR, Rice FL. Air-Stimulated ATP Release from Keratinocytes Occurs through Connexin Hemichannels. PLoS One. 2013; 8(2):e56744.
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Leeson S, Strichartz G. Kinetics of uptake and washout of lidocaine in rat sciatic nerve in vitro. Anesth Analg. 2013 Mar; 116(3):694-702.
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Ohri R, Blaskovich P, Wang JC, Pham L, Nichols G, Hildebrand W, Costa D, Scarborough N, Herman C, Strichartz G. Prolonged nerve block by microencapsulated bupivacaine prevents acute postoperative pain in rats. Reg Anesth Pain Med. 2012 Nov-Dec; 37(6):607-15.
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Huang L, Gao YJ, Wang J, Strichartz G. Shifts in cell-type expression accompany a diminishing role of spinal p38-mapkinase activation over time during prolonged postoperative pain. Anesthesiology. 2011 Dec; 115(6):1281-90.
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Ji RR, Xu ZZ, Strichartz G, Serhan CN. Emerging roles of resolvins in the resolution of inflammation and pain. Trends Neurosci. 2011 Nov; 34(11):599-609.
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Colvin AC, Wang CF, Soens MA, Mitani AA, Strichartz G, Gerner P. Prolonged cutaneous analgesia with transdermal application of amitriptyline and capsaicin. Reg Anesth Pain Med. 2011 May-Jun; 36(3):236-40.
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Montmayeur JP, Barr TP, Kam SA, Packer SJ, Strichartz GR. ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Ga(q/11). Pharmacol Res. 2011 Sep; 64(3):258-67.
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Barr TP, Kam S, Khodorova A, Montmayeur JP, Strichartz GR. New perspectives on the endothelin axis in pain. Pharmacol Res. 2011 Jun; 63(6):532-40.
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Huang L, Wang CF, Serhan CN, Strichartz G. Enduring prevention and transient reduction of postoperative pain by intrathecal resolvin D1. Pain. 2011 Mar; 152(3):557-65.
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Wang CF, Pancaro C, Gerner P, Strichartz G. Prolonged suppression of postincisional pain by a slow-release formulation of lidocaine. Anesthesiology. 2011 Jan; 114(1):135-49.
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Gerner P, Wang CF, Lee BS, Suzuki S, Degirolami U, Gandhi A, Knaack D, Strichartz G. The relationship between functional sciatic nerve block duration and the rate of release of lidocaine from a controlled-release matrix. Anesth Analg. 2010 Jul; 111(1):221-9.
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Khodorova A, Strichartz GR. Remarkably long-lasting tachyphylaxis of pain responses to ET-1: evidence against central nervous system involvement. Can J Physiol Pharmacol. 2010 Jun; 88(6):668-75.
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Khodorova A, Strichartz GR. Contralateral paw sensitization following injection of endothelin-1: effects of local anesthetics differentiate peripheral and central processes. Neuroscience. 2010 Jan 20; 165(2):553-60.
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Strichartz G. Beyond neurons: the complex sources of pain transduction. Pain. 2010 Feb; 148(2):180-1.
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Colucci V, Strichartz G, Jolesz F, Vykhodtseva N, Hynynen K. Focused ultrasound effects on nerve action potential in vitro. Ultrasound Med Biol. 2009 Oct; 35(10):1737-47.
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Shrestha S, Gracias NG, Mujenda F, Khodorova A, Vasko MR, Strichartz GR. Local antinociception induced by endothelin-1 in the hairy skin of the rat's back. J Pain. 2009 Jul; 10(7):702-14.
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Khodorova A, Richter J, Vasko MR, Strichartz G. Early and late contributions of glutamate and CGRP to mechanical sensitization by endothelin-1. J Pain. 2009 Jul; 10(7):740-9.
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Feng B, Strichartz G. Endothelin-1 raises excitability and reduces potassium currents in sensory neurons. Brain Res Bull. 2009 Aug 14; 79(6):345-50.
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Wang CF, Djalali AG, Gandhi A, Knaack D, De Girolami U, Strichartz G, Gerner P. An absorbable local anesthetic matrix provides several days of functional sciatic nerve blockade. Anesth Analg. 2009 Mar; 108(3):1027-33.
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Khodorova A, Montmayeur JP, Strichartz G. Endothelin receptors and pain. J Pain. 2009 Jan; 10(1):4-28.
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Hans G, Schmidt BL, Strichartz G. Nociceptive sensitization by endothelin-1. Brain Res Rev. 2009 Apr; 60(1):36-42.
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Ji RR, Gereau RW, Malcangio M, Strichartz GR. MAP kinase and pain. Brain Res Rev. 2009 Apr; 60(1):135-48.
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Kamath R, Strichartz G, Rosenthal D. Cartilage toxicity from local anesthetics. Skeletal Radiol. 2008 Oct; 37(10):871-3.
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Sugimoto K, Kissin I, Strichartz G. A high concentration of resiniferatoxin inhibits ion channel function in clonal neuroendocrine cells. Anesth Analg. 2008 Jul; 107(1):318-24.
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Strichartz GR. Novel ideas of local anaesthetic actions on various ion channels to ameliorate postoperative pain. Br J Anaesth. 2008 Jul; 101(1):45-7.
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Gerner P, Strichartz GR. Sensory and motor complications of local anesthetics. Muscle Nerve. 2008 Apr; 37(4):421-5.
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McNally MA, Baek RC, Avila RL, Seyfried TN, Strichartz GR, Kirschner DA. Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis. J Negat Results Biomed. 2007; 6:8.
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Mujenda FH, Duarte AM, Reilly EK, Strichartz GR. Cutaneous endothelin-A receptors elevate post-incisional pain. Pain. 2007 Dec 15; 133(1-3):161-73.
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Zhang J, Hadlock T, Gent A, Strichartz GR. Tetracaine-membrane interactions: effects of lipid composition and phase on drug partitioning, location, and ionization. Biophys J. 2007 Jun 1; 92(11):3988-4001.
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Yanagidate F, Strichartz GR. Local anesthetics. Handb Exp Pharmacol. 2007; (177):95-127.
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Weinberg GL, Ripper R, Murphy P, Edelman LB, Hoffman W, Strichartz G, Feinstein DL. Lipid infusion accelerates removal of bupivacaine and recovery from bupivacaine toxicity in the isolated rat heart. Reg Anesth Pain Med. 2006 Jul-Aug; 31(4):296-303.
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Balonov K, Khodorova A, Strichartz GR. Tactile allodynia initiated by local subcutaneous endothelin-1 is prolonged by activation of TRPV-1 receptors. Exp Biol Med (Maywood). 2006 Jun; 231(6):1165-70.
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Amir R, Argoff CE, Bennett GJ, Cummins TR, Durieux ME, Gerner P, Gold MS, Porreca F, Strichartz GR. The role of sodium channels in chronic inflammatory and neuropathic pain. J Pain. 2006 May; 7(5 Suppl 3):S1-29.
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Yanagidate F, Strichartz GR. Bupivacaine inhibits activation of neuronal spinal extracellular receptor-activated kinase through selective effects on ionotropic receptors. Anesthesiology. 2006 Apr; 104(4):805-14.
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Zhuang ZY, Wen YR, Zhang DR, Borsello T, Bonny C, Strichartz GR, Decosterd I, Ji RR. A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance. J Neurosci. 2006 Mar 29; 26(13):3551-60.
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Duarte AM, Pospisilova E, Reilly E, Mujenda F, Hamaya Y, Strichartz GR. Reduction of postincisional allodynia by subcutaneous bupivacaine: findings with a new model in the hairy skin of the rat. Anesthesiology. 2005 Jul; 103(1):113-25.
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Lambert DH, Strichartz GR. In defense of in vitro findings. Anesthesiology. 2004 Nov; 101(5):1246-7; author reply 1247-8.
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Lambert DH, Lambert LA, Strichartz GR. Questioning the mechanism of nerve injury. Anesthesiology. 2004 Nov; 101(5):1249; author reply 1249-50.
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Ji RR, Strichartz G. Cell signaling and the genesis of neuropathic pain. Sci STKE. 2004 Sep 28; 2004(252):reE14.
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Son SL, Wong K, Strichartz G. Antagonism by local anesthetics of sodium channel activators in the presence of scorpion toxins: two mechanisms for competitive inhibition. Cell Mol Neurobiol. 2004 Aug; 24(4):565-77.
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Houck CS, Khodorova A, Reale AM, Strichartz GR, Davar G. Sensory fibers resistant to the actions of tetrodotoxin mediate nocifensive responses to local administration of endothelin-1 in rats. Pain. 2004 Aug; 110(3):719-26.
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Nakamura T, Popitz-Bergez F, Birknes J, Strichartz GR. The critical role of concentration for lidocaine block of peripheral nerve in vivo: studies of function and drug uptake in the rat. Anesthesiology. 2003 Nov; 99(5):1189-97.
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Sinnott CJ, Strichartz GR. Levobupivacaine versus ropivacaine for sciatic nerve block in the rat. Reg Anesth Pain Med. 2003 Jul-Aug; 28(4):294-303.
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Khodorova A, Navarro B, Jouaville LS, Murphy JE, Rice FL, Mazurkiewicz JE, Long-Woodward D, Stoffel M, Strichartz GR, Yukhananov R, Davar G. Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury. Nat Med. 2003 Aug; 9(8):1055-61.
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Araujo MC, Sinnott CJ, Strichartz GR. Multiple phases of relief from experimental mechanical allodynia by systemic lidocaine: responses to early and late infusions. Pain. 2003 May; 103(1-2):21-9.
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Taheri S, Cogswell LP, Gent A, Strichartz GR. Hydrophobic and ionic factors in the binding of local anesthetics to the major variant of human alpha1-acid glycoprotein. J Pharmacol Exp Ther. 2003 Jan; 304(1):71-80.
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Sinnott CJ, Cogswell III LP, Johnson A, Strichartz GR. On the mechanism by which epinephrine potentiates lidocaine's peripheral nerve block. Anesthesiology. 2003 Jan; 98(1):181-8.
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Persaud N, Strichartz GR. Micromolar lidocaine selectively blocks propagating ectopic impulses at a distance from their site of origin. Pain. 2002 Sep; 99(1-2):333-40.
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Khodorova A, Fareed MU, Gokin A, Strichartz GR, Davar G. Local injection of a selective endothelin-B receptor agonist inhibits endothelin-1-induced pain-like behavior and excitation of nociceptors in a naloxone-sensitive manner. J Neurosci. 2002 Sep 1; 22(17):7788-96.
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Zhou Z, Davar G, Strichartz G. Endothelin-1 (ET-1) selectively enhances the activation gating of slowly inactivating tetrodotoxin-resistant sodium currents in rat sensory neurons: a mechanism for the pain-inducing actions of ET-1. J Neurosci. 2002 Aug 1; 22(15):6325-30.
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Nau C, Strichartz GR. Drug chirality in anesthesia. Anesthesiology. 2002 Aug; 97(2):497-502.
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Strichartz GR, Zhou Z, Sinnott C, Khodorova A. Therapeutic concentrations of local anaesthetics unveil the potential role of sodium channels in neuropathic pain. Novartis Found Symp. 2002; 241:189-201; discussion 202-5, 226-32.
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Zhou QL, Strichartz G, Davar G. Endothelin-1 activates ET(A) receptors to increase intracellular calcium in model sensory neurons. Neuroreport. 2001 Dec 4; 12(17):3853-7.
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Gokin AP, Philip B, Strichartz GR. Preferential block of small myelinated sensory and motor fibers by lidocaine: in vivo electrophysiology in the rat sciatic nerve. Anesthesiology. 2001 Dec; 95(6):1441-54.
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Cogswell LP, Raines DE, Parekh S, Jonas O, Maggio JE, Strichartz GR. Development of a novel probe for measuring drug binding to the F1*S variant of human alpha 1-acid glycoprotein. J Pharm Sci. 2001 Sep; 90(9):1407-23.
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Gokin AP, Fareed MU, Pan HL, Hans G, Strichartz GR, Davar G. Local injection of endothelin-1 produces pain-like behavior and excitation of nociceptors in rats. J Neurosci. 2001 Jul 15; 21(14):5358-66.
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Khodorova A, Meissner K, Leeson S, Strichartz GR. Lidocaine selectively blocks abnormal impulses arising from noninactivating Na channels. Muscle Nerve. 2001 May; 24(5):634-47.
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Nau C, Wang SY, Strichartz GR, Wang GK. Block of human heart hH1 sodium channels by the enantiomers of bupivacaine. Anesthesiology. 2000 Oct; 93(4):1022-33.
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Sinnott CJ, Garfield JM, Thalhammer JG, Strichartz GR. Addition of sodium bicarbonate to lidocaine decreases the duration of peripheral nerve block in the rat. Anesthesiology. 2000 Oct; 93(4):1045-52.
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Strichartz G. Pathways and obstacles to local anesthesia, a personal account: the 2000 Gaston Labat lecture. Reg Anesth Pain Med. 2000 Sep-Oct; 25(5):447-51.
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Vladimirov M, Nau C, Mok WM, Strichartz G. Potency of bupivacaine stereoisomers tested in vitro and in vivo: biochemical, electrophysiological, and neurobehavioral studies. Anesthesiology. 2000 Sep; 93(3):744-55.
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Khodorova AB, Strichartz GR. The addition of dilute epinephrine produces equieffectiveness of bupivacaine enantiomers for cutaneous analgesia in the rat. Anesth Analg. 2000 Aug; 91(2):410-6.
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Chamberlain LJ, Yannas IV, Hsu HP, Strichartz GR, Spector M. Near-terminus axonal structure and function following rat sciatic nerve regeneration through a collagen-GAG matrix in a ten-millimeter gap. J Neurosci Res. 2000 Jun 1; 60(5):666-77.
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Kohane DS, Lu NT, Gökgöl-Kline AC, Shubina M, Kuang Y, Hall S, Strichartz GR, Berde CB. The local anesthetic properties and toxicity of saxitonin homologues for rat sciatic nerve block in vivo. Reg Anesth Pain Med. 2000 Jan-Feb; 25(1):52-9.
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Moller RA, Datta S, Strichartz GR. Beta-estradiol acutely potentiates the depression of cardiac excitability by lidocaine and bupivacaine. J Cardiovasc Pharmacol. 1999 Nov; 34(5):718-27.
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Nau C, Wang SY, Strichartz GR, Wang GK. Point mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers. Mol Pharmacol. 1999 Aug; 56(2):404-13.
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Sinnott CJ, Garfield JM, Strichartz GR. Differential efficacy of intravenous lidocaine in alleviating ipsilateral versus contralateral neuropathic pain in the rat. Pain. 1999 Apr; 80(3):521-31.
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Kohane DS, Kuang Y, Lu NT, Langer R, Strichartz GR, Berde CB. Vanilloid receptor agonists potentiate the in vivo local anesthetic activity of percutaneously injected site 1 sodium channel blockers. Anesthesiology. 1999 Feb; 90(2):524-34.
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Xiong Z, Bukusoglu C, Strichartz GR. Local anesthetics inhibit the G protein-mediated modulation of K+ and Ca++ currents in anterior pituitary cells. Mol Pharmacol. 1999 Jan; 55(1):150-8.
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Xiong Z, Strichartz GR. Inhibition by local anesthetics of Ca2+ channels in rat anterior pituitary cells. Eur J Pharmacol. 1998 Dec 11; 363(1):81-90.
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Chamberlain LJ, Yannas IV, Hsu HP, Strichartz G, Spector M. Collagen-GAG substrate enhances the quality of nerve regeneration through collagen tubes up to level of autograft. Exp Neurol. 1998 Dec; 154(2):315-29.
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Davar G, Hans G, Fareed MU, Sinnott C, Strichartz G. Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve. Neuroreport. 1998 Jul 13; 9(10):2279-83.
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Kohane DS, Yieh J, Lu NT, Langer R, Strichartz GR, Berde CB. A re-examination of tetrodotoxin for prolonged duration local anesthesia. Anesthesiology. 1998 Jul; 89(1):119-31.
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Lambert DH, Strichartz GR. Every problem is an opportunity, or one person's poison is another person's remedy. Reg Anesth Pain Med. 1998 Jan-Feb; 23(1):3-6.
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Huang JH, Thalhammer JG, Raymond SA, Strichartz GR. Susceptibility to lidocaine of impulses in different somatosensory afferent fibers of rat sciatic nerve. J Pharmacol Exp Ther. 1997 Aug; 282(2):802-11.
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Popitz-Bergez FA, Leeson S, Thalhammer JG, Strichartz GR. Intraneural lidocaine uptake compared with analgesic differences between pregnant and nonpregnant rats. Reg Anesth. 1997 Jul-Aug; 22(4):363-71.
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Vladimirov M, Thalhammer JG, Hunt N, Feldman HS, Strichartz G. Neurophysiologic actions and neurological consequences of veratridine on the rat sciatic nerve. Anesthesiology. 1997 Apr; 86(4):945-56.
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Choi RH, Birknes JK, Popitz-Bergez FA, Kissin I, Strichartz GR. Pharmacokinetic nature of tachyphylaxis to lidocaine: peripheral nerve blocks and infiltration anesthesia in rats. Life Sci. 1997; 61(12):PL 177-84.
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Lambert DH, Lambert LA, Strichartz GR. Radicular irritation after spinal anesthesia. Anesthesiology. 1996 Nov; 85(5):1216-7.
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Waikar SS, Thalhammer JG, Raymond SA, Huang JH, Chang DS, Strichartz GR. Mechanoreceptive afferents exhibit functionally-specific activity dependent changes in conduction velocity. Brain Res. 1996 May 20; 721(1-2):91-100.
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Strichartz G. Protracted relief of experimental neuropathic pain by systemic local anesthetics. How, where, and when. Anesthesiology. 1995 Oct; 83(4):654-5.
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Strichartz GR, Lambert DH. Neurotoxicity of 5% lignocaine. Br J Anaesth. 1995 Sep; 75(3):376.
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Popitz-Bergez FA, Leeson S, Strichartz GR, Thalhammer JG. Relation between functional deficit and intraneural local anesthetic during peripheral nerve block. A study in the rat sciatic nerve. Anesthesiology. 1995 Sep; 83(3):583-92.
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Strichartz GR, Hall S, Magnani B, Hong CY, Kishi Y, Debin JA. The potencies of synthetic analogues of saxitoxin and the absolute stereoselectivity of decarbamoyl saxitoxin. Toxicon. 1995 Jun; 33(6):723-37.
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Thalhammer JG, Vladimirova M, Bershadsky B, Strichartz GR. Neurologic evaluation of the rat during sciatic nerve block with lidocaine. Anesthesiology. 1995 Apr; 82(4):1013-25.
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McHugh J, Mok WM, Wang GK, Strichartz G. Irreversible inhibition of sodium current and batrachotoxin binding by a photoaffinity-derivatized local anesthetic. J Gen Physiol. 1995 Feb; 105(2):267-87.
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Li YM, Wingrove DE, Too HP, Marnerakis M, Stimson ER, Strichartz GR, Maggio JE. Local anesthetics inhibit substance P binding and evoked increases in intracellular Ca2+. Anesthesiology. 1995 Jan; 82(1):166-73.
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Desai S, Hadlock T, Messam C, Chafetz R, Strichartz G. Ionization and adsorption of a series of local anesthetics in detergent micelles: studies of drug fluorescence. J Pharmacol Exp Ther. 1994 Oct; 271(1):220-8.
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Bainton CR, Strichartz GR. Concentration dependence of lidocaine-induced irreversible conduction loss in frog nerve. Anesthesiology. 1994 Sep; 81(3):657-67.
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Wang ZY, Feng DM, Wang YL, Tung SR, Wong K, Strichartz GR, Folkers K, Håkanson R. Pharmacological assessment of spantide II analogues. Eur J Pharmacol. 1994 Aug 1; 260(2-3):121-8.
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DeBin JA, Wood MR, Pfenninger KH, Strichartz GR. A chloride channel reconstituted from fetal rat brain growth cones. J Membr Biol. 1994 Jul; 141(1):7-19.
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Shin HC, Park HJ, Raymond SA, Strichartz GR. Potentiation by capsaicin of lidocaine's tonic impulse block in isolated rat sciatic nerve. Neurosci Lett. 1994 Jun 6; 174(1):14-6.
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Lambert LA, Lambert DH, Strichartz GR. Irreversible conduction block in isolated nerve by high concentrations of local anesthetics. Anesthesiology. 1994 May; 80(5):1082-93.
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Wang ZY, Tung SR, Strichartz GR, Håkanson R. Investigation of the specificity of FK 888 as a tachykinin NK1 receptor antagonist. Br J Pharmacol. 1994 Apr; 111(4):1342-6.
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Wang ZY, Tung SR, Strichartz GR, Håkanson R. Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission. Br J Pharmacol. 1994 Jan; 111(1):179-84.
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Thalhammer JG, Raymond SA, Popitz-Bergez FA, Strichartz GR. Modality-dependent modulation of conduction by impulse activity in functionally characterized single cutaneous afferents in the rat. Somatosens Mot Res. 1994; 11(3):243-57.
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Wilder RT, Berde CB, Griggs CT, Chickalingaiah R, Strichartz G. Chronic exposure to lidocaine does not alter flux through sodium channels in cultured neuronal cells. Reg Anesth. 1993 Sep-Oct; 18(5):283-9.
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Chernoff DM, Strichartz GR, Piwnica-Worms D. Membrane potential determination in large unilamellar vesicles with hexakis(2-methoxyisobutylisonitrile)technetium(I). Biochim Biophys Acta. 1993 Apr 22; 1147(2):262-6.
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DeBin JA, Maggio JE, Strichartz GR. Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion. Am J Physiol. 1993 Feb; 264(2 Pt 1):C361-9.
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Butterworth JF, Strichartz GR. The alpha 2-adrenergic agonists clonidine and guanfacine produce tonic and phasic block of conduction in rat sciatic nerve fibers. Anesth Analg. 1993 Feb; 76(2):295-301.
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Wong K, Strichartz GR, Raymond SA. On the mechanisms of potentiation of local anesthetics by bicarbonate buffer: drug structure-activity studies on isolated peripheral nerve. Anesth Analg. 1993 Jan; 76(1):131-43.
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Wood MR, DeBin J, Strichartz GR, Pfenninger KH. Plasmalemmal insertion and modification of sodium channels at the nerve growth cone. J Neurosci. 1992 Aug; 12(8):2948-59.
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Lee-Son S, Wang GK, Concus A, Crill E, Strichartz G. Stereoselective inhibition of neuronal sodium channels by local anesthetics. Evidence for two sites of action? Anesthesiology. 1992 Aug; 77(2):324-35.
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Raymond SA, Abrams SB, Raemer DB, Philip JH, Strichartz GR. The NerveSeeker: a system for automated nerve localization. Reg Anesth. 1992 May-Jun; 17(3):151-62.
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Drachman D, Strichartz G. Potassium channel blockers potentiate impulse inhibition by local anesthetics. Anesthesiology. 1991 Dec; 75(6):1051-61.
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Gold MR, Strichartz GR. Acute effects of repetitive depolarization on sodium current in chick myocytes. Am J Physiol. 1991 Jun; 260(6 Pt 2):H1810-8.
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Gold MR, Strichartz GR. Use-dependent block of atrial sodium current by ethylisopropylamiloride. J Cardiovasc Pharmacol. 1991 May; 17(5):792-9.
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Schneider M, Datta S, Strichartz G. A preferential inhibition of impulses in C-fibers of the rabbit vagus nerve by veratridine, an activator of sodium channels. Anesthesiology. 1991 Feb; 74(2):270-80.
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Guo XT, Castle NA, Chernoff DM, Strichartz GR. Comparative inhibition of voltage-gated cation channels by local anesthetics. Ann N Y Acad Sci. 1991; 625:181-99.
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DeBin JA, Strichartz GR. Chloride channel inhibition by the venom of the scorpion Leiurus quinquestriatus. Toxicon. 1991; 29(11):1403-8.
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Hahin R, Wang GK, Shapiro BI, Strichartz G. Alterations in sodium channel gating produced by the venom of the marine mollusc Conus striatus. Toxicon. 1991; 29(2):245-59.
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Raymond SA, Thalhammer JG, Popitz-Bergez F, Strichartz GR. Changes in axonal impulse conduction correlate with sensory modality in primary afferent fibers in the rat. Brain Res. 1990 Sep 3; 526(2):318-21.
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Strichartz GR, Sanchez V, Arthur GR, Chafetz R, Martin D. Fundamental properties of local anesthetics. II. Measured octanol:buffer partition coefficients and pKa values of clinically used drugs. Anesth Analg. 1990 Aug; 71(2):158-70.
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Chernoff DM, Strichartz GR. Kinetics of local anesthetic inhibition of neuronal sodium currents. pH and hydrophobicity dependence. Biophys J. 1990 Jul; 58(1):69-81.
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Butterworth JF, Strichartz GR. Molecular mechanisms of local anesthesia: a review. Anesthesiology. 1990 Apr; 72(4):711-34.
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Raymond SA, Strichartz GR. Further comments on the failure of impulse propagation in nerves marginally blocked by local anesthetic. Anesth Analg. 1990 Jan; 70(1):121-2.
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Chernoff DM, Strichartz GR. Tonic and phasic block of neuronal sodium currents by 5-hydroxyhexano-2',6'-xylide, a neutral lidocaine homologue. J Gen Physiol. 1989 Jun; 93(6):1075-90.
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Raymond SA, Strichartz GR. The long and short of differential block. Anesthesiology. 1989 May; 70(5):725-8.
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Raymond SA, Steffensen SC, Gugino LD, Strichartz GR. The role of length of nerve exposed to local anesthetics in impulse blocking action. Anesth Analg. 1989 May; 68(5):563-70.
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Benzon HT, Strichartz GR, Gissen AJ, Shanks CA, Covino BG, Datta S. Developmental neurophysiology of mammalian peripheral nerves and age-related differential sensitivity to local anaesthetic. Br J Anaesth. 1988 Dec; 61(6):754-60.
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Strichartz GR. Through the eye of the channel: considerations of a reductionist view of general anesthesia. Anesthesiology. 1988 Aug; 69(2):155-6.
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Butterworth JF, Lief PA, Strichartz GR. The pH-dependent local anesthetic activity of diethylaminoethanol, a procaine metabolite. Anesthesiology. 1988 Apr; 68(4):501-6.
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Castle NA, Strichartz GR. Palytoxin induces a relatively non-selective cation permeability in frog sciatic nerve which can be inhibited by cardiac glycosides. Toxicon. 1988; 26(10):941-51.
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Butterworth JF, Moran JR, Whitesides GM, Strichartz GR. Limited nerve impulse blockade by "leashed" local anesthetics. J Med Chem. 1987 Aug; 30(8):1295-302.
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Benzon HT, Gissen AJ, Strichartz GR, Avram MJ, Covino BG. The effect of polyethylene glycol on mammalian nerve impulses. Anesth Analg. 1987 Jun; 66(6):553-9.
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Tamplin ML, Colwell RR, Hall S, Kogure K, Strichartz GR. Sodium-channel inhibitors produced by enteropathogenic Vibrio cholerae and Aeromonas hydrophila. Lancet. 1987 Apr 25; 1(8539):975.
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Wang GK, Brodwick MS, Eaton DC, Strichartz GR. Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. The role of channel activation. J Gen Physiol. 1987 Apr; 89(4):645-67.
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Sanchez V, Arthur GR, Strichartz GR. Fundamental properties of local anesthetics. I. The dependence of lidocaine's ionization and octanol:buffer partitioning on solvent and temperature. Anesth Analg. 1987 Feb; 66(2):159-65.
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Chesnut TJ, Carpenter DO, Strichartz GR. Effects of venom from Conus striatus on the delayed rectifier potassium current of molluscan neurons. Toxicon. 1987; 25(3):267-78.
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Strichartz G, Rando T, Wang GK. An integrated view of the molecular toxinology of sodium channel gating in excitable cells. Annu Rev Neurosci. 1987; 10:237-67.
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Bokesch PM, Raymond SA, Strichartz GR. Dependence of lidocaine potency on pH and PCO2. Anesth Analg. 1987 Jan; 66(1):9-17.
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Strichartz GR, Wang GK. Rapid voltage-dependent dissociation of scorpion alpha-toxins coupled to Na channel inactivation in amphibian myelinated nerves. J Gen Physiol. 1986 Sep; 88(3):413-35.
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Moczydlowski E, Olivera BM, Gray WR, Strichartz GR. Discrimination of muscle and neuronal Na-channel subtypes by binding competition between [3H]saxitoxin and mu-conotoxins. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5321-5.
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Bokesch PM, Post C, Strichartz G. Structure-activity relationship of lidocaine homologs producing tonic and frequency-dependent impulse blockade in nerve. J Pharmacol Exp Ther. 1986 Jun; 237(3):773-81.
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Rando TA, Wang GK, Strichartz GR. The interaction between the activator agents batrachotoxin and veratridine and the gating processes of neuronal sodium channels. Mol Pharmacol. 1986 May; 29(5):467-77.
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Rando TA, Strichartz GR. Saxitoxin blocks batrachotoxin-modified sodium channels in the node of Ranvier in a voltage-dependent manner. Biophys J. 1986 Mar; 49(3):785-94.
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Strichartz G, Rando T, Hall S, Gitschier J, Hall L, Magnani B, Bay CH. On the mechanism by which saxitoxin binds to and blocks sodium channels. Ann N Y Acad Sci. 1986; 479:96-112.
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Post C, Butterworth JF, Strichartz GR, Karlsson JA, Persson CG. Tachykinin antagonists have potent local anaesthetic actions. Eur J Pharmacol. 1985 Nov 19; 117(3):347-54.
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Wang GK, Strichartz G. Kinetic analysis of the action of Leiurus scorpion alpha-toxin on ionic currents in myelinated nerve. J Gen Physiol. 1985 Nov; 86(5):739-62.
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Jackson FR, Gitschier J, Strichartz GR, Hall LM. Genetic modifications of voltage-sensitive sodium channels in Drosophila: gene dosage studies of the seizure locus. J Neurosci. 1985 May; 5(5):1144-51.
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Wildsmith JA, Strichartz GR. Local anaesthetic drugs--an historical perspective. Br J Anaesth. 1984 Sep; 56(9):937-9.
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Strichartz G. Structural determinants of the affinity of saxitoxin for neuronal sodium channels. Electrophysiological studies on frog peripheral nerve. J Gen Physiol. 1984 Aug; 84(2):281-305.
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Strichartz GR, Small RK, Pfenninger KH. Components of the plasma membrane of growing axons. III. Saxitoxin binding to sodium channels. J Cell Biol. 1984 Apr; 98(4):1444-52.
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Jackson FR, Wilson SD, Strichartz GR, Hall LM. Two types of mutants affecting voltage-sensitive sodium channels in Drosophila melanogaster. Nature. 1984 Mar 8-14; 308(5955):189-91.
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Dodt HU, Strichartz GR, Zimmermann M. Phenol solutions differentially block conduction in cutaneous nerve fibers of the cat. Neurosci Lett. 1983 Dec 11; 42(3):323-7.
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Strichartz G, Bar-Sagi D, Prives J. Differential expression of sodium channel activities during the development of chick skeletal muscle cells in culture. J Gen Physiol. 1983 Sep; 82(3):365-84.
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Wang GK, Strichartz GR. Purification and physiological characterization of neurotoxins from venoms of the scorpions centruroides sculpturatus and leiurus quinquestriatus. Mol Pharmacol. 1983 Mar; 23(2):519-33.
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Wang GK, Strichartz G. Simultaneous modifications of sodium channel gating by two scorpion toxins. Biophys J. 1982 Nov; 40(2):175-9.
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Strichartz G. Structure of the saxitoxin binding site at sodium channels in nerve membranes. Exchange of tritium from bound toxin molecules. Mol Pharmacol. 1982 Mar; 21(2):343-50.
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Cohen I, Attwell D, Strichartz G. The dependence of the maximum rate of rise of the action potential upstroke on membrane properties. Proc R Soc Lond B Biol Sci. 1981 Dec 9; 214(1194):85-98.
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Hahin R, Strichartz G. Effects of deuterium oxide on the rate and dissociation constants for saxitoxin and tetrodotoxin action. Voltage-clamp studies on frog myelinated nerve. J Gen Physiol. 1981 Aug; 78(2):113-39.
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Strichartz GR. Current concepts of the mechanism of action of local anesthetics. J Dent Res. 1981 Aug; 60(8):1460-70.
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Strichartz GR, Hanson Bay CM. Saxitoxin binding in nerves from walking legs of the lobster Homarus americanus. Two classes of receptors. J Gen Physiol. 1981 Feb; 77(2):205-21.
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Strichartz GR. Pharmacological properties of sodium channels in nerve membranes. Adv Neurol. 1981; 31:343-56.
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Strichartz G. Use-dependent conduction block produced by volatile general anesthetic agents. Acta Anaesthesiol Scand. 1980 Oct; 24(5):402-6.
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Strichartz GR, Oxford GS, Ramon F. Effects of the dipolar form of phloretin on potassium conductance in squid giant axons. Biophys J. 1980 Aug; 31(2):229-46.
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Bay CM, Strichartz GR. Saxitoxin binding to sodium channels of rat skeletal muscles. J Physiol. 1980 Mar; 300:89-103.
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Gitschier J, Strichartz GR, Hall LM. Saxitoxin binding to sodium channels in head extracts from wild-type and tetrodotoxin-sensitive strains of Drosophila melanogaster. Biochim Biophys Acta. 1980 Jan 25; 595(2):291-303.
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Krueger BK, Ratzlaff RW, Strichartz GR, Blaustein MP. Saxitoxin binding to synaptosomes, membranes, and solubilized binding sites from rat brain. J Membr Biol. 1979 Nov 30; 50(3-4):287-310.
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Tang CM, Strichartz GR, Orkand RK. Sodium channels in axons and glial cells of the optic nerve of Necturus maculosa. J Gen Physiol. 1979 Nov; 74(5):629-42.
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Strichartz GR, Rogart RB, Ritchie JM. Binding of radioactively labeled saxitoxin to the squid giant axon. J Membr Biol. 1979 Aug; 48(4):357-64.
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Strichartz GR, Chiu SY, Ritchie JM. The effect of delta9-tetrahydrocannabinol on the activation of sodium conductance in node of Ranvier. J Pharmacol Exp Ther. 1978 Dec; 207(3):801-9.
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Strichartz G, Cohen I. Vmax as a measure of GNa in nerve and cardiac membranes. Biophys J. 1978 Jul; 23(1):153-6.
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Strichartz G. Effects of tertiary local anesthetics and their quaternary derivatives on sodium channels of nerve membranes [proceedings]. Biophys J. 1977 Jun; 18(3):353-4.
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Cohen IS, Strichartz GR. On the voltage-dependent action of tetrodotoxin. Biophys J. 1977 Mar; 17(3):275-9.
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Ritchie JM, Rogart RB, Strichartz GR. A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves. J Physiol. 1976 Oct; 261(2):477-94.
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Strichartz G. Molecular mechanisms of nerve block by local anesthetics. Anesthesiology. 1976 Oct; 45(4):421-41.
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Ritchie JM, Rogart RB, Strichartz G. Proceedings: Binding to nerve and muscle of saxitoxin labelled by a new method of tritium exchange. J Physiol. 1976 Jun; 258(2):99P-100P.
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Hille B, Ritchie JM, Strichartz GR. The effect of surface charge on the nerve membrane on the action of tetrodotoxin and saxitoxin in frog myelinated nerve. J Physiol. 1975 Aug; 250(1):34P-35P.
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Henderson R, Ritchie JM, Strichartz GR. Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane. Proc Natl Acad Sci U S A. 1974 Oct; 71(10):3936-40.
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Henderson R, Strichartz G. Ion fluxes through the sodium channels of garfish olfactory nerve membranes. J Physiol. 1974 Apr; 238(2):329-42.
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Henderson R, Ritchie JM, Strichartz GR. The binding of labelled saxitoxin to the sodium channels in nerve membranes. J Physiol. 1973 Dec; 235(3):783-804.
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Henderson R, Ritchie JM, Strichartz GR. The binding of labelled saxitoxin to mammalian non-myelinated nerve fibres. J Physiol. 1973 Jul; 232(1):53P-54P.
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Strichartz GR. The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine. J Gen Physiol. 1973 Jul; 62(1):37-57.
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Strichartz GR, Chance B. Absorbance changes at 520 nm caused by salt addition to chloroplast suspensions in the dark. Biochim Biophys Acta. 1972 Jan 21; 256(1):71-84.
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Strichartz GR. The Necessity for beta-Carotene in the 518 Nanometer Absorbance Change. Plant Physiol. 1971 Nov; 48(5):553-8.