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S. James Adelstein, Ph.D., M.D.

TitlePaul C. Cabot Distinguished Professor of Medical Biophysics
InstitutionHarvard Medical School
DepartmentRadiology
AddressHarvard Medical School
Rm 207-A
180 Longwood Ave
Boston MA 02115
Phone617/432-3997
Fax617/432-0173

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Balagurumoorthy P, Xu X, Wang K, Adelstein SJ, Kassis AI. Effect of distance between decaying (125)I and DNA on Auger-electron induced double-strand break yield. Int J Radiat Biol. 2012 Dec; 88(12):998-1008.
    View in: PubMed
  2. Mamlouk O, Balagurumoorthy P, Wang K, Adelstein SJ, Kassis AI. Bystander effect in tumor cells produced by Iodine-125 labeled human lymphocytes. Int J Radiat Biol. 2012 Dec; 88(12):1019-27.
    View in: PubMed
  3. Adelstein SJ, Bernert BR, Hill HA. Bert Lester Vallee: a lasting legacy. J Inorg Biochem. 2012 Jun; 111:100-3.
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  4. Fahey FH, Treves ST, Adelstein SJ. Minimizing and communicating radiation risk in pediatric nuclear medicine. J Nucl Med Technol. 2012 Mar; 40(1):13-24.
    View in: PubMed
  5. Yang Y, Adelstein SJ, Kassis AI. Target discovery from data mining approaches. Drug Discov Today. 2012 Feb; 17 Suppl:S16-23.
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  6. Yang Y, Wang K, Li W, Adelstein SJ, Kassis AI. Human placental alkaline phosphatase-mediated hydrolysis correlates tightly with the electrostatic contribution from tail group. Chem Biol Drug Des. 2011 Dec; 78(6):923-31.
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  7. Fahey FH, Treves ST, Adelstein SJ. Minimizing and communicating radiation risk in pediatric nuclear medicine. J Nucl Med. 2011 Aug; 52(8):1240-51.
    View in: PubMed
  8. Balagurumoorthy P, Adelstein SJ, Kassis AI. Novel method for quantifying radiation-induced single-strand-break yields in plasmid DNA highlights 10-fold discrepancy. Anal Biochem. 2011 Oct 15; 417(2):242-6.
    View in: PubMed
  9. Yang Y, Adelstein SJ, Kassis AI. General approach to identifying potential targets for cancer imaging by integrated bioinformatics analysis of publicly available genomic profiles. Mol Imaging. 2011 Apr; 10(2):123-34.
    View in: PubMed
  10. Yang Y, Adelstein SJ, Kassis AI. Integrated bioinformatics analysis for cancer target identification. Methods Mol Biol. 2011; 719:527-45.
    View in: PubMed
  11. Hricak H, Brenner DJ, Adelstein SJ, Frush DP, Hall EJ, Howell RW, McCollough CH, Mettler FA, Pearce MS, Suleiman OH, Thrall JH, Wagner LK. Managing radiation use in medical imaging: a multifaceted challenge. Radiology. 2011 Mar; 258(3):889-905.
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  12. Yang Y, Adelstein SJ, Kassis AI. Target discovery from data mining approaches. Drug Discov Today. 2009 Feb; 14(3-4):147-54.
    View in: PubMed
  13. Singh A, Yang Y, Adelstein SJ, Kassis AI. Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution. Int J Radiat Biol. 2008 Dec; 84(12):1001-10.
    View in: PubMed
  14. Rebischung C, Hoffmann D, Stefani L, Desruet MD, Wang K, Adelstein SJ, Artignan X, Vincent F, Gauchez AS, Zhang H, Fagret D, Vuillez J, Kassis AI, Balosso J. First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR. Int J Radiat Biol. 2008 Dec; 84(12):1123-9.
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  15. Howell RW, Martin RF, Nikjoo H, Pomplun E, Terrissol M, Watanable R, Yasui L, Kassis AI, Adelstein SJ. Meeting overview. Int J Radiat Biol. 2008 Dec; 84(12):957-8.
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  16. Balagurumoorthy P, Wang K, Adelstein SJ, Kassis AI. DNA double-strand breaks induced by decay of (123)I-labeled Hoechst 33342: role of DNA topology. Int J Radiat Biol. 2008 Dec; 84(12):976-83.
    View in: PubMed
  17. Yang Y, Pospisil P, Iyer LK, Adelstein SJ, Kassis AI. Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer. PLoS One. 2008; 3(11):e3661.
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  18. Balagurumoorthy P, Adelstein SJ, Kassis AI. Method to eliminate linear DNA from mixture containing nicked circular, supercoiled, and linear plasmid DNA. Anal Biochem. 2008 Oct 1; 381(1):172-4.
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  19. Balagurumoorthy P, Chen K, Adelstein SJ, Kassis AI. Auger electron-induced double-strand breaks depend on DNA topology. Radiat Res. 2008 Jul; 170(1):70-82.
    View in: PubMed
  20. Kassis AI, Korideck H, Wang K, Pospisil P, Adelstein SJ. Novel prodrugs for targeting diagnostic and therapeutic radionuclides to solid tumors. Molecules. 2008; 13(2):391-404.
    View in: PubMed
  21. Wang K, Adelstein SJ, Kassis AI. DMSO increases radioiodination yield of radiopharmaceuticals. Appl Radiat Isot. 2008 Jan; 66(1):50-9.
    View in: PubMed
  22. Singh A, Chen K, Adelstein SJ, Kassis AI. Synthesis of coumarin-polyamine-based molecular probe for the detection of hydroxyl radicals generated by gamma radiation. Radiat Res. 2007 Aug; 168(2):233-42.
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  23. Wang K, Kirichian AM, Aowad AF, Adelstein SJ, Kassis AI. Evaluation of chemical, physical, and biologic properties of tumor-targeting radioiodinated quinazolinone derivative. Bioconjug Chem. 2007 May-Jun; 18(3):754-64.
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  24. Pospisil P, Wang K, Al Aowad AF, Iyer LK, Adelstein SJ, Kassis AI. Computational modeling and experimental evaluation of a novel prodrug for targeting the extracellular space of prostate tumors. Cancer Res. 2007 Mar 1; 67(5):2197-205.
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  25. Chen K, Aowad AF, Adelstein SJ, Kassis AI. Molecular-docking-guided design, synthesis, and biologic evaluation of radioiodinated quinazolinone prodrugs. J Med Chem. 2007 Feb 22; 50(4):663-73.
    View in: PubMed
  26. Adelstein SJ. Radiation Risk. Pediatric Nuclear Medicine, Treves, ST (ed.). 2007.
  27. Chen K, Wang K, Kirichian AM, Al Aowad AF, Iyer LK, Adelstein SJ, Kassis AI. In silico design, synthesis, and biological evaluation of radioiodinated quinazolinone derivatives for alkaline phosphatase-mediated cancer diagnosis and therapy. Mol Cancer Ther. 2006 Dec; 5(12):3001-13.
    View in: PubMed
  28. Urashima T, Nagasawa H, Wang K, Adelstein SJ, Little JB, Kassis AI. Induction of apoptosis in human tumor cells after exposure to Auger electrons: comparison with gamma-ray exposure. Nucl Med Biol. 2006 Nov; 33(8):1055-63.
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  29. Balagurumoorthy P, Chen K, Bash RC, Adelstein SJ, Kassis AI. Mechanisms underlying production of double-strand breaks in plasmid DNA after decay of 125I-Hoechst. Radiat Res. 2006 Aug; 166(2):333-44.
    View in: PubMed
  30. Pospisil P, Iyer LK, Adelstein SJ, Kassis AI. A combined approach to data mining of textual and structured data to identify cancer-related targets. BMC Bioinformatics. 2006; 7:354.
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  31. Kishikawa H, Wang K, Adelstein SJ, Kassis AI. Inhibitory and stimulatory bystander effects are differentially induced by Iodine-125 and Iodine-123. Radiat Res. 2006 Jun; 165(6):688-94.
    View in: PubMed
  32. Semnani ES, Wang K, Adelstein SJ, Kassis AI. 5-[123I/125I]iodo-2'-deoxyuridine in metastatic lung cancer: radiopharmaceutical formulation affects targeting. J Nucl Med. 2005 May; 46(5):800-6.
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  33. Kassis AI, Adelstein SJ. Radiobiologic principles in radionuclide therapy. J Nucl Med. 2005 Jan; 46 Suppl 1:4S-12S.
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  34. Urashima T, Wang K, Adelstein SJ, Kassis AI. Activation of diverse pathways to apoptosis by (125)IdUrd and gamma-photon exposure. Int J Radiat Biol. 2004 Nov-Dec; 80(11-12):867-74.
    View in: PubMed
  35. Chen K, Adelstein SJ, Kassis AI. Molecular simulation of ligand-binding with DNA: implications for 125I-labeled pharmaceutical design. Int J Radiat Biol. 2004 Nov-Dec; 80(11-12):921-6.
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  36. Kassis AI, Kirichian AM, Wang K, Semnani ES, Adelstein SJ. Therapeutic potential of 5-[125I]iodo-2'-deoxyuridine and methotrexate in the treatment of advanced neoplastic meningitis. Int J Radiat Biol. 2004 Nov-Dec; 80(11-12):941-6.
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  37. Adelstein SJ, Fry RJ, Little JB, Sinclair WK. A scientific, moral and diplomatic misstep. Radiat Res. 2004 Jun; 161(6):621.
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  38. Wong R, Favaloro E, Pollock W, Wilson R, Hendle M, Adelstein S, Baumgart K, Homes P, Smith S, Steele R, Sturgess A, Gillis D. A multi-centre evaluation of the intra-assay and inter-assay variation of commercial and in-house anti-cardiolipin antibody assays. Pathology. 2004 Apr; 36(2):182-92.
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  39. Wong RC, Gillis D, Adelstein S, Baumgart K, Favaloro EJ, Hendle MJ, Homes P, Pollock W, Smith S, Steele RH, Sturgess A, Wilson RJ. Consensus guidelines on anti-cardiolipin antibody testing and reporting. Pathology. 2004 Feb; 36(1):63-8.
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  40. Adelstein SJ. Introduction to the 27th Lauriston S. Taylor Lecture. Health Phys. 2004; 87:238-239.
  41. Bodei L, Kassis AI, Adelstein SJ, Mariani G. Radionuclide therapy with iodine-125 and other auger-electron-emitting radionuclides: experimental models and clinical applications. Cancer Biother Radiopharm. 2003 Dec; 18(6):861-77.
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  42. Britz-Cunningham SH, Adelstein SJ. Molecular targeting with radionuclides: state of the science. J Nucl Med. 2003 Dec; 44(12):1945-61.
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  43. Wong RC, Steele RH, Reeves GE, Wilson RJ, Pink A, Adelstein S. Antibody and genetic testing in coeliac disease. Pathology. 2003 Aug; 35(4):285-304.
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  44. Adelstein SJ, Kassis AI, Bodei L, Mariani G. Radiotoxicity of iodine-125 and other auger-electron-emitting radionuclides: background to therapy. Cancer Biother Radiopharm. 2003 Jun; 18(3):301-16.
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  45. Kassis AI, Adelstein SJ. Considerations in the selected of radionuclides for cancer therapy. Welch MJ, Redvanly CS, ed. Handbook of radiopharmaceuticals: radiochemistry and applications. 2003; 767-793.
  46. Adelstein SJ. Biologic responses to low doses of ionizing radiation: adaptive response versus bystander effect. J Nucl Med. 2003 Jan; 44(1):125; author reply 125-6.
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  47. Xue LY, Butler NJ, Makrigiorgos GM, Adelstein SJ, Kassis AI. Bystander effect produced by radiolabeled tumor cells in vivo. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13765-70.
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  48. Ho NH, Harapanhalli RS, Dahman BA, Chen K, Wang K, Adelstein SJ, Kassis AI. Synthesis and biologic evaluation of a radioiodinated quinazolinone derivative for enzyme-mediated insolubilization therapy. Bioconjug Chem. 2002 Mar-Apr; 13(2):357-64.
    View in: PubMed
  49. Adelstein SJ, chairman of report committee. Absorbed-dose specification in nuclear medicine, ICRU Report No 67. 2002.
  50. Adelstein SJ. Robley Evans and what physics can do for medicine. Cancer Biother Radiopharm. 2001 Jun; 16(3):179-85.
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  51. Walicka MA, Adelstein SJ, Kassis AI. Chemical modification of 5-[125I]iodo-2'-deoxyuridine toxicity in mammalian cells in vitro. Int J Radiat Biol. 2001 May; 77(5):625-30.
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  52. Adelstein SJ. The 2000 NCRP Lauriston S. Taylor lecture--administered radioactivity: unde venimus quoque imus. National Council on Radiation Protection and Measurements. Health Phys. 2001 Apr; 80(4):317-24.
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  53. Adelstein SJ. The 2000 NCRP Lauriston S. Taylor lecture-administered radioactivity: unde venimus quoque imus. Health Phys. 2001; 80:317-324.
  54. Walicka MA, Ding Y, Adelstein SJ, Kassiss AI. Toxicity of DNA-incorporated iodine-125: quantifying the direct and indirect effects. Radiat Res. 2000 Sep; 154(3):326-30.
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  55. Walicka MA, Ding Y, Adelstein SJ, Kassis AI. Morphological transformation of C3H 10T1/2 cells by 99mTc-cardiolite. J Nucl Med. 2000 Sep; 41(9):1545-51.
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  56. Mariani G, Bodei L, Adelstein SJ, Kassis AI. Emerging roles for radiometabolic therapy of tumors based on auger electron emission. J Nucl Med. 2000 Sep; 41(9):1519-21.
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  57. Kassis AI, Walicka MA, Adelstein SJ. Double-strand break yield following 125I decay--effects of DNA conformation. Acta Oncol. 2000; 39(6):721-6.
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  58. Kassis AI, Dahman BA, Adelstein SJ. In vivo therapy of neoplastic meningitis with methotrexate and 5. Acta Oncol. 2000; 39(6):731-7.
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  59. Adelstein SJ. The 4th International Symposium in Lund on biophysical aspects of Auger processes-a review. SSInews. 2000; 8(2):11-12.
  60. Walicka MA, Ding Y, Roy AM, Harapanhalli RS, Adelstein SJ, Kassis AI. Cytotoxicity of [125I]iodoHoechst 33342: contribution of scavengeable effects. Int J Radiat Biol. 1999 Dec; 75(12):1579-87.
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  61. Kassis AI, Harapanhalli RS, Adelstein SJ. Strand breaks in plasmid DNA after positional changes of Auger electron-emitting iodine-125: direct compared to indirect effects. Radiat Res. 1999 Nov; 152(5):530-8.
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  62. Adelstein SJ. Administered radionuclides in pregnancy. Teratology. 1999 Apr; 59(4):236-9.
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  63. Adelstein SJ. Radionuclide exposure during pregnancy: "60 Minutes" film. Teratology. 1999 Apr; 59(4):301.
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  64. Kassis AI, Harapanhalli RS, Adelstein SJ. Comparison of strand breaks in plasmid DNA after positional changes of Auger electron-emitting iodine-125. Radiat Res. 1999 Feb; 151(2):167-76.
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  65. Kassis AI, Adelstein SJ, inventors. Metho for radioisotopic detection and localization of inflammation in a host. 1998.
  66. Walicka MA, Vaidyanathan G, Zalutsky MR, Adelstein SJ, Kassis AI. Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211. Radiat Res. 1998 Sep; 150(3):263-8.
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  67. Kassis AI, Wen PY, Van den Abbeele AD, Baranowska-Kortylewicz J, Makrigiorgos GM, Metz KR, Matalka KZ, Cook CU, Sahu SK, Black PM, Adelstein SJ. 5-[125I]iodo-2'-deoxyuridine in the radiotherapy of brain tumors in rats. J Nucl Med. 1998 Jul; 39(7):1148-54.
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  68. Harapanhalli RS, Roy AM, Adelstein SJ, Kassis AI. [125I/127I/131I]Iodorhodamine: synthesis, cellular localization, and biodistribution in athymic mice bearing human tumor xenografts and comparison with [99mTc]hexakis(2-methoxyisobutylisonitrile). J Med Chem. 1998 Jun 4; 41(12):2111-7.
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  69. Harapanhalli RS, Matalka KZ, Jones PL, Mahmood A, Adelstein SJ, Kassis AI. Lysine-directed conjugation of ethidium homodimer to B72.3 antibody: retention of immunoreactivity but altered tumor targeting. Nucl Med Biol. 1998 Apr; 25(3):267-78.
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  70. Kassis AI, Foulon CF, Adelstein SJ, inventors. Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from stannyl precursors. 1998.
  71. Walicka MA, Adelstein SJ, Kassis AI. Indirect mechanisms contribute to biological effects produced by decay of DNA-incorporated iodine-125 in mammalian cells in vitro: double-strand breaks. Radiat Res. 1998 Feb; 149(2):134-41.
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  72. Walicka MA, Adelstein SJ, Kassis AI. Indirect mechanisms contribute to biological effects produced by decay of DNA-incorporated iodine-125 in mammalian cells in vitro: clonogenic survival. Radiat Res. 1998 Feb; 149(2):142-6.
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  73. Adelstein SJ, Howell RW, Humm JL, Makrigiorgos GM, Wessels BW. On the conceptual basis for dose quantities in nuclear medicine. ICRU News. 1998; 1:4-10.
  74. Sample SB, Adlestein SJ, Cerny J, Goodstein DL, McCormick RL, O'Connor JD, Perkins FE, Shapiro BJ, Thomas JL, Wiley JD. Report and recommendations of the Committee on Postdoctoral Education, Association of American Universities, March 31, 1998. 1998.
  75. Sahu SK, Kortylewicz ZP, Baranowska-Kortylewicz J, Taube RA, Adelstein SJ, Kassis AI. Strand breaks after the decay of iodine-125 in proximity to plasmid pBR322 DNA. Radiat Res. 1997 Apr; 147(4):401-8.
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  76. Sahu SK, Wen PY, Foulon CF, Nagel JS, Black PM, Adelstein SJ, Kassis AI. Intrathecal 5-[125I]iodo-2'-deoxyuridine in a rat model of leptomeningeal metastases. J Nucl Med. 1997 Mar; 38(3):386-90.
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  77. Kassis AI, Adelstein SJ, inventors. Method for radioisotopic detection and localization of inflammation in a host. 1997.
  78. Kassis AI, Foulon CF, Adelstein SJ, inventors. Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from stannyl precursors. 1996.
  79. Harapanhalli RS, McLaughlin LW, Howell RW, Rao DV, Adelstein SJ, Kassis AI. [125I/127I]iodoHoechst 33342: synthesis, DNA binding, and biodistribution. J Med Chem. 1996 Nov 22; 39(24):4804-9.
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  80. Kassis AI, Foulon CF, Adelstein SJ, inventors. Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides. 1996.
  81. Kassis AI, Adelstein SJ, Mariani G. Radiolabeled nucleoside analogs in cancer diagnosis and therapy. Q J Nucl Med. 1996 Sep; 40(3):301-19.
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  82. Kassis AI, Foulon CF, Adelstein SJ, inventors. Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides. 1996.
  83. Mariani G, Collecchi P, Baldassarri S, Di Luca L, Buralli S, Fontanini G, Baranowska-Kortylewicz J, Adelstein SJ, Kassis AI. Tumor uptake and mitotic activity pattern of 5-[125I]iodo-2'- deoxyuridine after intravesical infusion in patients with bladder cancer. J Nucl Med. 1996 Apr; 37(4 Suppl):16S-19S.
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  84. Mariani G, Di Sacco S, Volterrani D, Di Luca L, Buralli S, Di Stefano R, Baranowska-Kortylewicz J, Bonora D, Matteucci F, Ricci S, Bellina CR, Falcone A, Salvadori PA, Mosca F, Adelstein SJ, Kassis AI. Tumor targeting by intra-arterial infusion of 5-[123I]iodo-2'-deoxyuridine in patients with liver metastases from colorectal cancer. J Nucl Med. 1996 Apr; 37(4 Suppl):22S-25S.
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  85. Kassis AI, Adelstein SJ. Preclinical animal studies with radioiododeoxyuridine. J Nucl Med. 1996 Apr; 37(4 Suppl):10S-12S.
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  86. Foulon CF, Adelstein SJ, Kassis AI. Kit formulation for the preparation of radiolabeled iododeoxyuridine by demetallation. J Nucl Med. 1996 Apr; 37(4 Suppl):1S-3S.
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  87. Kassis AI, Tumeh SS, Wen PY, Baranowska-Kortylewicz J, Van den Abbeele AD, Zimmerman RE, Carvalho PA, Garada BM, DeSisto WC, Bailey NO, Castronovo FP, Mariani G, Black PM, Adelstein SJ. Intratumoral administration of 5-[123I]iodo-2'-deoxyuridine in a patient with a brain tumor. J Nucl Med. 1996 Apr; 37(4 Suppl):19S-22S.
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  88. Kassis AI, Jones PL, Matalka KZ, Adelstein SJ. Antibody-dependent signal amplification in tumor xenografts after pretreatment with biotinylated monoclonal antibody and avidin or streptavidin. J Nucl Med. 1996 Feb; 37(2):343-52.
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  89. Van den Abbeele AD, Tutrone RF, Berman RM, Baranowska-Kortylewicz J, Barclay PD, Richie JP, Adelstein SJ, Kassis AI. Tumor-targeting potential of radioiodinated iododeoxyuridine in bladder cancer. J Nucl Med. 1996 Feb; 37(2):315-20.
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  90. Kassis AI, Adelstein SJ. 5-[125]iodo-2'-deoxyuridine in the radiotherapy of solid CNS tumors in rats. Acta Oncol. 1996; 35(7):935-9.
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  91. Adelstein SJ, Kassis AI. Strand breaks in plasmid DNA following positional changes of Auger-electron-emitting radionuclides. Acta Oncol. 1996; 35(7):797-801.
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  92. Mariani G, Di Sacco S, Bonini R, Di Luca L, Buralli S, Bonora D, Ricci S, Baranowska-Kortylewicz J, Adelstein SJ, Falcone A, Kassis AI. Biochemical modulation by 5-fluorouracil and 1-folinic acid of tumor uptake of intra-arterial 5-[123I]iodo-2'deoxyuridine in patients with liver metastases from colorectal cancer. Acta Oncol. 1996; 35(7):941-5.
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  93. Foulon CF, Zhang YZ, Adelstein SJ, Kassis AI. Instantaneous preparation of radiolabeled 5-iodo-2'-deoxyuridine. Appl Radiat Isot. 1995 Oct; 46(10):1039-46.
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  94. Sahu SK, Kassis AI, Makrigiorgos GM, Baranowska-Kortylewicz J, Adelstein SJ. The effects of indium-111 decay on pBR322 DNA. Radiat Res. 1995 Feb; 141(2):193-8.
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  95. Adelstein SJ, Kassis AI. Radiobiology. Wagner HN Jr, Szabo Z, Buchanan JW, ed. Principles of nuclear medicine. 1995; 95-105.
  96. Adelstein SJ, Manning FJ, eds. . Isotopes for medicine and the life sciences. Report of Committee on Biomedical Isotopes, Division of Health Sciences Policy, Institute of Medicine. 1995.
  97. Adelstein SJ. Radiation risk. Treves ST, ed. Pediatric nuclear medicine. 1995; 17-23.
  98. Howell RW, Kassis AI, Adelstein SJ, Rao DV, Wright HA, Hamm RN, Turner JE, Sastry KS. Radiotoxicity of platinum-195m-labeled trans-platinum (II) in mammalian cells. Radiat Res. 1994 Oct; 140(1):55-62.
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  99. Kassis AI, Adelstein SJ, inventors. Diagnosis of tumors with 5-radioiodo-2'-deoxyuridine. 1994.
  100. Tosteson DC, Adelstein SJ, Carver ST, ed. . New pathways to medical education: Learning to Learn at Harvard Medical School. 1994.
  101. Adelstein SJ, Carver ST, Goldman H, Ramos MB. Transitional organization. Tosteson DC, Adelstein SJ, Carver ST, ed. New pathways to medical education: Learning to learn at Harvard Medical School. 1994; 139-157.
  102. Adelstein SJ, Ramos MB. Searching. Tosteson DC, Adelstein SJ, Carver ST, ed. New pathways to medical education: Learning to learn at Harvard Medical School. 1994; 14-29.
  103. Adelstein SJ. Merrill C. Sosman Lecture. The Auger process: a therapeutic promise? AJR Am J Roentgenol. 1993 Apr; 160(4):707-13.
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  104. Adelstein SJ. Preparing a grant proposal. Invest Radiol. 1993 Apr; 28 Suppl 2:S10-2.
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  105. Mariani G, Giuliani L, Baranowska-Kortylewicz J, Collecchi P, Meucci G, Di Luca L, Viacava P, Van den Abbeele AD, Bevilacqua G,Salvadori PA, Adelstein SJ, Kassis AI. Intratumoral injection of 5-[125I]iodo-2'-deoxyuridine in patients with breast cancer. Hofer R, Bergmann H, Sinzinger H, eds. Radioactive isotopes in clinical medicine and research. 1993; 188-193.
  106. Kassis AI, Adelstein SJ. Therapeutic potential of internally administered radionuclides. Black PMcL, Schoene WC, Lampson LA, eds. Contemporary issues in neurological surgery. Astrocytomas: Diagnosis, treatment, and biology. 1993; 290-299.
  107. Kassis AI, Adelstein SJ, inventors. Diagnosis of tumors with 5-(123I)iodo-2'-deoxyuridine. 1992.
  108. Adelstein SJ. The Auger process: A therapeutic promise?. Thirtieth Merrill C. Sosman Lecture, Brigham and Women's Hospital. 1992; (160):707-713.
  109. Kassis AI, Adelstein SJ. Does nonuniformity of dose have implications for radiation protection? J Nucl Med. 1992 Mar; 33(3):384-7.
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  110. Makrigiorgos GM, Berman RM, Baranowska-Kortylewicz J, Bump E, Humm JL, Adelstein SJ, Kassis AI. DNA damage produced in V79 cells by DNA-incorporated iodine-123: a comparison with iodine-125. Radiat Res. 1992 Mar; 129(3):309-14.
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  111. Kassis AI, Adelstein SJ, inventors. Treatment of tumors with 5-radioiodo-2'deoxyuridine. 1991.
  112. Baranowska-Kortylewicz J, Makrigiorgos GM, Van den Abbeele AD, Berman RM, Adelstein SJ, Kassis AI. 5-[123I]iodo-2'-deoxyuridine in the radiotherapy of an early ascites tumor model. Int J Radiat Oncol Biol Phys. 1991 Nov; 21(6):1541-51.
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  113. Kassis AI, Guptill WE, Taube RA, Adelstein SJ. Radiotoxicity of 5-[125I]iodo-2'-deoxyuridine in mammalian cells following treatment with 5-fluoro-2'-deoxyuridine. J Nucl Biol Med. 1991 Jul-Sep; 35(3):167-73.
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  114. Mariani G, Ito S, Nayak RC, Baranowska-Kortylewicz J, Venkateshan CN, Van den Abbeele AD, Eisenbarth GS, Adelstein SJ, Kassis AI. Capping and internalization of a monoclonal antibody-surface antigen complex: a possible mode of interaction of monoclonal antibodies and tumor cells. J Nucl Biol Med. 1991 Apr-Jun; 35(2):111-9.
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  115. Van den Abbeele AD, Aaronson RA, Daher S, Taube RA, Adelstein SJ, Kassis AI. Antigen-binding site protection during radiolabeling leads to a higher immunoreactive fraction. J Nucl Med. 1991 Jan; 32(1):116-22.
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  116. Adelstein SJ. Medical education for the 1990s. Clin Neurosurg. 1991; 37:217-24.
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  117. Adelstein SJ, Kassis AI, Baranowska-Kortylewicz J, van den Abbeele AD, Mariani G, Ito S. Potential for tumor therapy with iodine-125 labeled immunoglobulins. Int J Rad Appl Instrum B. 1991; 18(1):43-4.
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  118. Kassis AI, Van den Abbeele AD, Wen PY, Baranowska-Kortylewicz J, Aaronson RA, DeSisto WC, Lampson LA, Black PM, Adelstein SJ. Specific uptake of the auger electron-emitting thymidine analogue 5-[123I/125I]iodo-2'-deoxyuridine in rat brain tumors: diagnostic and therapeutic implications in humans. Cancer Res. 1990 Aug 15; 50(16):5199-203.
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  119. Makrigiorgos GM, Adelstein SJ, Kassis AI. Cellular radiation dosimetry and its implications for estimation of radiation risks. Illustrative results with technetium 99m-labeled microspheres and macroaggregates. JAMA. 1990 Aug 1; 264(5):592-5.
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  120. Makrigiorgos GM, Ito S, Baranowska-Kortylewicz J, Vinter DW, Iqbal A, Van den Abbeele AD, Adelstein SJ, Kassis AI. Inhomogeneous deposition of radiopharmaceuticals at the cellular level: experimental evidence and dosimetric implications. J Nucl Med. 1990 Aug; 31(8):1358-63.
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  121. Whaley JM, Kassis AI, Kinsey BM, Adelstein SJ, Little JB. Mutation induction by 125iodoacetylproflavine, a DNA-intercalating agent, in human cells. Int J Radiat Biol. 1990 Jun; 57(6):1087-103.
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  122. van den Abbeele AD, Aaronson RA, Taube RA, Adelstein SJ, Kassis AI. Preadsorption of radiolabeled monoclonal antibodies to liver and spleen tissues leads to higher tumor-to-normal-tissue ratios. J Nucl Med Allied Sci. 1990 Apr-Jun; 34(2):94-102.
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  123. Baranowska-Kortylewicz J, Adelstein SJ, Kassis AI. 5-iodo-2'-deoxyuridine-protein conjugates: synthesis and enzymatic degradation. Sel Cancer Ther. 1990; 6(1):1-13.
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  124. Committee on Promoting Research Collaboration (Adelstein SJ, Benedek GB, Co-chair) of Board on Physics and Astronomy, Commission on Physical Sciences, Mathematics and Resources, National Research Council and Division of Health Sciences Policy, Institute of Medicine. Interdisciplinary research: Promoting collaboration between the life sciences and medicine and the physical sciences and engineering. 1990.
  125. Mariani G, Kassis AI, Adelstein SJ. Antibody internalization by tumor cells: implications for tumor diagnosis and therapy. J Nucl Med Allied Sci. 1990 Jan-Mar; 34(1):51-4.
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  126. Makrigiorgos G, Adelstein SJ, Kassis AI. Auger electron emitters: insights gained from in vitro experiments. Radiat Environ Biophys. 1990; 29(2):75-91.
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  127. Kinsey BM, Fayad F, Venkateshan CN, Adelstein SJ, Kassis AI. Synthesis and biological activity of the intercalating agent 3-acetamido-5-[123/125I]iodo-6-aminoacridine. Int J Rad Appl Instrum B. 1990; 17(3):341-6.
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  128. Kinsey BM, Van den Abbeele AD, Adelstein SJ, Kassis AI. Absence of preferential uptake of [125I]iododihydrorhodamine 123 by four human tumor xenografts. Cancer Res. 1989 Nov 1; 49(21):5986-8.
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  129. Makrigiorgos GM, Adelstein SJ, Kassis AI. Limitations of conventional internal dosimetry at the cellular level. J Nucl Med. 1989 Nov; 30(11):1856-64.
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  130. Makrigiorgos GM, Kassis AI, Baranowska-Kortylewicz J, McElvany KD, Welch MJ, Sastry KS, Adelstein SJ. Radiotoxicity of 5-[123I]iodo-2'-deoxyuridine in V79 cells: a comparison with 5-[125I]iodo-2'-deoxyuridine. Radiat Res. 1989 Jun; 118(3):532-44.
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  131. Kassis AI, Fayad F, Kinsey BM, Sastry KS, Adelstein SJ. Radiotoxicity of an 125I-labeled DNA intercalator in mammalian cells. Radiat Res. 1989 May; 118(2):283-94.
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  132. Wanzer SH, Federman DD, Adelstein SJ, Cassel CK, Cassem EH, Cranford RE, Hook EW, Lo B, Moertel CG, Safar P, et al. The physician's responsibility toward hopelessly ill patients. A second look. N Engl J Med. 1989 Mar 30; 320(13):844-9.
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  133. Mariani G, Abbeele AD, Venkateshan CN, Kaldany A, Ito S, Adelstein SJ, Kassis AI. Monoclonal antibody internalization by tumor cells: an experimental model for potential radioimmunotherapy applications. Int J Rad Appl Instrum B. 1989; 16(2):147-50.
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  134. Van den Abbeele AD, Aaronson RA, Adelstein SJ, Kassis AI. Does the in vitro testing of the immunoreactivity of an antibody reflect its in vivo behavior? J Nucl Med Allied Sci. 1988 Oct-Dec; 32(4):260-7.
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  135. Macklis RM, Kinsey BM, Kassis AI, Ferrara JL, Atcher RW, Hines JJ, Coleman CN, Adelstein SJ, Burakoff SJ. Radioimmunotherapy with alpha-particle-emitting immunoconjugates. Science. 1988 May 20; 240(4855):1024-6.
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  136. Kinsey BM, Kassis AI, Adelstein SJ, inventors. Dihydrorhodamines and halogenated derivatives thereof. 1988.
  137. Kinsey BM, Kassis AI, Adelstein SJ, inventors. Dihydrorhodamines and halogenated derivatives thereof. 1987.
  138. Kinsey BM, Kassis AI, Fayad F, Layne WW, Adelstein SJ. Synthesis and biological studies of iodinated (127/125I) derivatives of rhodamine 123. J Med Chem. 1987 Oct; 30(10):1757-61.
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  139. Adelstein SJ. Uncertainty and relative risks of radiation exposure. JAMA. 1987 Aug 7; 258(5):655-7.
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  140. Kassis AI, Fayad F, Kinsey BM, Sastry KS, Taube RA, Adelstein SJ. Radiotoxicity of 125I in mammalian cells. Radiat Res. 1987 Aug; 111(2):305-18.
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  141. Mee LK, Adelstein SJ. Radiation damage to histone H2A by the primary aqueous radicals. Radiat Res. 1987 May; 110(2):155-60.
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  142. Adelstein SJ. Preparing a grant proposal. Invest Radiol. 1987 Mar; 22(3):250-2.
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  143. Layne WW, Kassis AI, Van den Abbeele A, Kinsey BM, Adelstein SJ. HPLC analysis of the dissociation and recombination of rabbit immunoglobulin G. J Immunol Methods. 1987 Feb 11; 96(2):195-9.
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  144. Adelstein SJ, Kassis AI. Radiobiologic implications of the microscopic distribution of energy from radionuclides. Int J Rad Appl Instrum B. 1987; 14(3):165-9.
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  145. Sinclair WK, Adelstein SJ, Carter MW, Harley JH, Moeller DW. Ionizing radiation exposure of the population of the United States, NCRP Report No 93. 1987.
  146. Kassis AI, Adelstein SJ, Bloomer WD. Therapeutic Implications of Auger-emitting radionuclides. Spencer RP, Seevers RH, Friedman AM, ed. Radionuclides in therapy. 1987; 119-134.
  147. Mee LK, Adelstein SJ. Formation of strand breaks in the DNA of gamma-irradiated chromatin. Radiat Environ Biophys. 1987; 26(1):13-22.
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  148. Kassis AI, Sastry KS, Adelstein SJ. Kinetics of uptake, retention, and radiotoxicity of 125IUdR in mammalian cells: implications of localized energy deposition by Auger processes. Radiat Res. 1987 Jan; 109(1):78-89.
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  149. Marks MA, Adelstein SJ. Radiation doses from radionuclides administered for therapy. Clin Oncol. 1986; 5:109-124.
  150. Tumeh SS, Treves S, Adelstein SJ. Radionuclides in genitourinary disorders. Walsh PC, Gittes RF, Perlmutter AD, Stamey TA, ed. Campbell's urology. 1986; 358-375.
  151. Kassis AI, Harris CR, Adelstein SJ, Ruth TJ, Lambrecht R, Wolf AP. The in vitro radiobiology of astatine-211 decay. Radiat Res. 1986 Jan; 105(1):27-36.
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  152. Adelstein SJ, Bloomer WD, Kassis AI, Sastry KSR. The potential use of alpha and Auger-electron emitting radionuclides for therapy. Winkler C, ed. Nuclear medicine in clinical oncology. 1986; 408-412.
  153. Milius RA, McLaughlin WH, Lambrecht RM, Wolf AP, Carroll JJ, Adelstein SJ, Bloomer WD. Organoastatine chemistry. Astatination via electrophilic destannylation. Int J Rad Appl Instrum A. 1986; 37(8):799-802.
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  154. Zalutsky MR, Venkatesan PP, English RJ, Shortkroff S, Sledge CB, Adelstein SJ. Radiation synovectomy with 165Dy-FHMA: lymph node uptake and radiation dosimetry calculations. Int J Nucl Med Biol. 1986; 12(6):457-65.
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  155. Kassis AI, Adelstein SJ. Chemotoxicity of indium-111 oxine in mammalian cells. J Nucl Med. 1985 Feb; 26(2):187-90.
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  156. Kassis AI, Sastry KS, Adelstein SJ. Intracellular distribution and radiotoxicity of chromium-51 in mammalian cells: Auger-electron dosimetry. J Nucl Med. 1985 Jan; 26(1):59-67.
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  157. Bloomer WD, McLaughlin WH, Adelstein SJ, Wolf AP. Therapeutic applications of Auger and alpha emitting radionuclides. Strahlentherapie. 1984 Dec; 160(12):755-7.
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  158. Kim HJ, Mee LK, Adelstein SJ, Taub IA, Carr SA, Reinhold VN. Binding site specificity of gamma-radiation-induced crosslinking between phenylalanine and a phenylalanine-containing tetrapeptide. Radiat Res. 1984 Oct; 100(1):30-40.
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  159. Adelstein SJ. Hevesy Nuclear Medicine Lecture. Henry N. Wagner, Jr. J Nucl Med. 1984 Aug; 25(8):934-9.
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  160. McLaughlin WH, Milius RA, Gill LM, Adelstein SJ, Bloomer WD. The oil-microcentrifuge assay: a rapid and sensitive method for analyzing specific [3H]estradiol binding in cultured cells. J Steroid Biochem. 1984 May; 20(5):1129-33.
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  161. Wanzer SH, Adelstein SJ, Cranford RE, Federman DD, Hook ED, Moertel CG, Safar P, Stone A, Taussig HB, van Eys J. The physician's responsibility toward hopelessly ill patients. N Engl J Med. 1984 Apr 12; 310(15):955-9.
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  162. Kim HJ, Mee LK, Adelstein SJ, Taub IA. Binding-site specificity of the radiolytically induced crosslinking of phenylalanine to glucagon. Radiat Res. 1984 Apr; 98(1):26-36.
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  163. Bloomer WD, McLaughlin WH, Lambrecht RM, Atcher RW, Mirzadeh S, Madara JL, Milius RA, Zalutsky MR, Adelstein SJ, Wolf AP. 211At radiocolloid therapy: further observations and comparison with radiocolloids of 32P, 165Dy, and 90Y. Int J Radiat Oncol Biol Phys. 1984 Mar; 10(3):341-8.
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  164. Jones AG, Abrams MJ, Davison A, Brodack JW, Toothaker AK, Adelstein SJ, Kassis AI. Biological studies of a new class of technetium complexes: the hexakis(alkylisonitrile)technetium(I) cations. Int J Nucl Med Biol. 1984; 11(3-4):225-34.
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  165. Adelstein SJ, Holman BL, Wagner HN Jr, Zaret BL. Optimal resources for radioactive tracer studies of the heart and circulation: Nuclear medicine study group. Report of Inter-Society Commission for Heart Disease Resources. Circulation. 1984; 70:524A-536A.
  166. Adelstein SJ. Heesy Nuclear Medicine Lecture: Henry N. Wagner, Jr. J Nucl Med. 1984; 25:934-939.
  167. Mee LK, Kim HJ, Adelstein SJ, Taub IA. Gamma-radiation-induced interactions between amino acids and glucagon. Radiat Res. 1984 Jan; 97(1):36-47.
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  168. Kassis AI, Adelstein SJ, Haydock C, Sastry KS. Thallium-201: an experimental and a theoretical radiobiological approach to dosimetry. J Nucl Med. 1983 Dec; 24(12):1164-75.
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  169. Kassis AI, Adelstein SJ, Wolf AP, Fowler JG, Shiue CY. Transient toxicity of 2-deoxy-2-[18F]fluoro-D-glucose in mammalian cells: concise communication. J Nucl Med. 1983 Nov; 24(11):1055-9.
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  170. Bloomer WD, McLaughlin WH, Milius RA, Weichselbaum RR, Adelstein SJ. Estrogen receptor-mediated cytotoxicity using iodine-125. J Cell Biochem. 1983; 21(1):39-45.
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  171. LeMotte PK, Adelstein SJ, Little JB. Malignant transformation induced by incorporated radionuclides in BALB/3T3 mouse embryo fibroblasts. Proc Natl Acad Sci U S A. 1982 Dec; 79(24):7763-7.
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  172. Bloomer WD, McLaughlin WH, Adelstein SJ. Therapeutic implications of iodine-125 cytotoxicity. Int J Radiat Oncol Biol Phys. 1982 Nov; 8(11):1903-8.
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  173. Brill AB, Adelstein SJ, Beck RN, Cloutier RJ, Ford MR, Johnston RE, Numerof P, Taplin GV, Winchell S. Nuclear Medicine - Factors influencing the choice and use of radionuclides in diagnosis and therapy, NCRP Report No 70. 1982.
  174. Kassis AI, Adelstein SJ, Haydock C, Sastry KS, McElvany KD, Welch MJ. Lethality of Auger electrons from the decay of bromine-77 in the DNA of mammalian cells. Radiat Res. 1982 May; 90(2):362-73.
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  175. Bloomer WD, Adelstein SJ. The mammalian radiation survival curve. J Nucl Med. 1982 Mar; 23(3):259-65.
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  176. Bloomer WD, Adelstein SJ. Radiation toxicology. Tu AT, ed. Survey of contemporary toxicology. 1982; 2:37-85.
  177. Bloomer WD, Adelstein SJ. Therapeutic applications of the Auger and alpha emitting radionuclides. Radioakt Isot Klin Forsch. 1982; 15:227-234.
  178. Adelstein SJ. Pitfalls and biases in evaluating diagnostic technologies. McNeilBJ, Cravalho EG, ed. Critical issues in medical technology. 1982; 67-79.
  179. Bloomer WD, McLaughlin WH, Neirinckx RD, Adelstein SJ, Gordon PR, Ruth TJ, Wolf AP. Astatine-211--tellurium radiocolloid cures experimental malignant ascites. Science. 1981 Apr 17; 212(4492):340-1.
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  180. Mee LK, Adelstein SJ. Predominance of core histones in formation of DNA--protein crosslinks in gamma-irradiated chromatin. Proc Natl Acad Sci U S A. 1981 Apr; 78(4):2194-8.
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  181. Kaplan WD, Zimmerman RE, Bloomer WD, Knapp RC, Adelstein SJ. Therapeutic intraperitoneal 32P: a clinical assessment of the dynamics of distribution. Radiology. 1981 Mar; 138(3):683-8.
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  182. McNeil BJ, Dudley RA, Hoop B, Metz C, Thompson M, Adelstein SJ. A cost-effectiveness analysis of screening for hepatitis B surface antigen in India. Med Decis Making. 1981; 1(4):345-59.
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  183. Bloomer WD, Adelstein SJ. Iodine-125 cytotoxicity: implications for therapy and estimation of radiation risk. Int J Nucl Med Biol. 1981; 8(2-3):171-8.
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  184. Thompson MS, McNeil BJ, Ganatra RD, Larsen PR, Adelstein SJ. Cost-effectiveness of screening for hypo- and hyperthyroidism in India. Med Decis Making. 1981; 1(1):44-58.
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  185. Kassis AI, Adelstein SJ, Haydock C, Sastry KS. Radiotoxicity of 75Se and 35S: theory and application to a cellular model. Radiat Res. 1980 Dec; 84(3):407-25.
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  186. Jones B, Abbruzzese AA, Hill TC, Adelstein SJ. Gallium-67-citrate scintigraphy in ulcerative colitis. Gastrointest Radiol. 1980 Aug 15; 5(3):267-72.
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  187. Bloomer WD, McLaughlin WH, Weichselbaum RR, Tonnesen GL, Hellman S, Seitz DE, Hanson RN, Adelstein SJ, Rosner AL, Burstein NA, Nove JJ, Little JB. Iodine-125-labelled tamoxifen is differentially cytoxic to cells containing oestrogen receptors. Int J Radiat Biol Relat Stud Phys Chem Med. 1980 Aug; 38(2):197-202.
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  188. McNeil BJ, Thompson M, Adelstein SJ. Cost effectiveness calculations for the diagnosis and treatment of tuberculous meningitis. Eur J Nucl Med. 1980 Jun; 5(3):271-6.
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  189. Kassis AI, Adelstein SJ. A rapid and reproducible method for the separation of cells from radioactive media. J Nucl Med. 1980 Jan; 21(1):88-90.
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  190. Mee LK, Adelstein SJ. Radiolysis of chromatin extracted from cultured mammalian cells: formation of DNA-protein cross links. Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Oct; 36(4):359-66.
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  191. Bloomer WD, Adelstein SJ. Mediastinal lymphoscintigraphy reflects cell kinetics of developing malignant ascites. Br J Radiol. 1979 Sep; 52(621):756-8.
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  192. McNeil BJ, Pace PD, Gray EB, Adelstein SJ, Wilson RE. Preoperative and follow-up bone scans in patients with primary carcinoma of the breast. Surg Gynecol Obstet. 1978 Nov; 147(5):745-8.
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  193. Adelstein SJ, McNeil BJ. A new diagnostic test for pulmonary embolism: how good and how costly? N Engl J Med. 1978 Aug 10; 299(6):305-7.
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  194. Mee LK, Adelstein SJ, Stein G. Radiolysis of chromatin extracted from cultured mammalian cells: production of alkali-labile strand damage in DNA. Int J Radiat Biol Relat Stud Phys Chem Med. 1978 May; 33(5):443-55.
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  195. Kaplan ML, Davis MA, Aschaffenburg PH, Adelstein SJ, Goldhaber P. Clinical, radiographic and scintigraphic findings in experimental periodontal disease in dogs. Arch Oral Biol. 1978; 23(4):273-8.
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  196. Bloomer WD, Adelstein SJ. Therapeutic application of iodine-125 labeled iododeoxyuridine in an early ascites tumour model. Curr Top Radiat Res Q. 1978 Jan; 12(1-4):513-25.
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  197. Bloomer WD, Adelstein SJ. 5-(125 I)-Iododeoxyuridine in experimental tumor therapy. Spencer RP, ed. Therapy in nuclear medicine. 1978; 177-183.
  198. Treves S, Adelstein SJ, McIlmoyle G. Radiology of the urinary tract: Radionuclides. Harrison JH, Gittes RF, Perlmutter AD,Stamey TA, Walsh PC, ed. Campbell's Urology. 1978; 270-278.
  199. Kaplan WD, Adelstein SJ. Tumor imaging. Schneider PB, Treves S, ed. Nuclear medicine in clinical practice. 1978; 1979-1999.
  200. McNeil BJ, Adelstein SJ. Pulmonary studies. Schneider PB, Treves S, ed. Nuclear medicine in clinical practice. 1978; 39-60.
  201. Bloomer WD, Adelstein SJ. 5-(125I)-iododeoxyuridine and the Auger effect: biological consequences and implications for therapy. Pathobiol Annu. 1978; 8:407-21.
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  202. Chan PC, Lisco E, Lisco H, Adelstein SJ. Cell survival and cytogenetic responses to 125I-UdR in cultured mammalian cells. Curr Top Radiat Res Q. 1978 Jan; 12(1-4):426-35.
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  203. Eilbert RF, Koehler AM, Sisterson JM, Wilson R, Adelstein SJ. Partial body calcium determination in bone by proton activation analysis. Phys Med Biol. 1977 Sep; 22(5):817-30.
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  204. Mee LK, Adelstein SJ, Steinhart CM, Lichtin NN. Reactions of aqueous L-methionine, L-phenylalanine, L-methionyl-L-phenylalanine, L-phenylalanyl-L-methionine and their mixtures with H atoms during steady radiolysis at pH 6.5. Radiat Res. 1977 Sep; 71(3):493-504.
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  205. Adelstein SJ, Maseri A. Radioindicators for the study of the heart: principles and applications. Prog Cardiovasc Dis. 1977 Jul-Aug; 20(1):3-17.
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  206. McNeil BJ, Collins JJ, Adelstein SJ. Rationale for seeking occult metastases in patients with bronchial carcinoma. Surg Gynecol Obstet. 1977 Mar; 144(3):389-93.
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  207. Bloomer WD, Adelstein SJ. 5-125I-iododeoxyuridine as prototype for radionuclide therapy with Auger emitters. Nature. 1977 Feb 17; 265(5595):620-1.
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  208. McNeil BJ, Adelstein SJ. The evaluation of diagnostic screening tests: A case study in hypertension. Potchen EJ, ed. Current concepts in radiology. 1977; 3:418-428.
  209. Adelstein SJ. Human factors in nuclear medicine quality control. Rhodes BA, ed. Quality control in nuclear medicine: Radiopharmaceuticals, instrumentation and in vitro assays. 1977; 89-95.
  210. Adelstein SJ. Organization of cardiovascular nuclear medicine units. Am J Cardiol. 1976 Nov 23; 38(6):761-5.
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  211. Schuessler H, Mee LK, Adelstein SJ. Reaction of ethanol radicals with ribonuclease. Int J Radiat Biol Relat Stud Phys Chem Med. 1976 Nov; 30(5):467-72.
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  212. Chan PC, Lisco E, Lisco H, Adelstein SJ. The radiotoxicity of iodine-125 in mammalian cells II. A comparative study on cell survival and cytogenetic responses to 125IUdR, 131TUdR, and 3HTdR. Radiat Res. 1976 Aug; 67(2):332-43.
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  213. McNeil BJ, Adelstein SJ. Determining the value of diagnostic and screening tests. J Nucl Med. 1976 Jun; 17(6):439-48.
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  214. McNeil BJ, Hessel SJ, Branch WT, Bjork L, Adelstein SJ. Measures of clinical efficacy. III. The value of the lung scan in the evaluation of young patients with pleuritic chest pain. J Nucl Med. 1976 Mar; 17(3):163-9.
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  215. Holman BL, McNeil BJ, Adelstein SJ. . Quantitative tracer kinetics. Gottschalk A, Potchen EJ, ed. Diagnostic nuclear medicine. 1976; 116-125.
  216. McNeil BJ, Holman BL, Adelstein SJ. Theoretical basis for blood flow measurement. Gottschalk A, Potchen EJ, ed. Diagnostic nuclear medicine. 1976; 109-115.
  217. Kaplan WD, Adelstein SJ. The radionuclide identification of tumors. Cancer. 1976 Jan; 37(1 suppl):487-95.
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  218. McIlmoyle G, Treves S, Adelstein SJ. Radionuclide studies of the kidney and bladder. Griffiths HJ, ed. Radiology of renal failure. 1976; 261-283.
  219. Kaplan ML, Garcia DA, Goldhaber P, Davis MA, Adelstein SJ. Uptake of 99mTe-Sn-EHDP in beagles with advanced periodontal disease. Calcif Tissue Res. 1975 Dec 18; 19(2):91-8.
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  220. Bradley EW, Chan PC, Adelstein SJ. The radiotoxicity of iodine-125 in mammalian cells. I. Effects on the survival curve of radioiodine incorporated into DNA. Radiat Res. 1975 Dec; 64(3):555-63.
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  221. Adelstein SJ, Jansen C, Wagner HN. Letter: Radioactive tracer studies of the heart and circulation. J Nucl Med. 1975 Oct; 16(10):959-60.
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  222. McNeil BJ, Adelstein SJ. Measures of clinical efficacy. The value of case finding in hypertensive renovascular disease. N Engl J Med. 1975 Jul 31; 293(5):221-6.
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  223. McNeil BJ, Keller E, Adelstein SJ. Primer on certain elements of medical decision making. N Engl J Med. 1975 Jul 31; 293(5):211-5.
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  224. McNeil BJ, Varady PD, Burrows BA, Adelstein SJ. Measures of clinical efficacy. Cost-effectiveness calculations in the diagnosis and treatment of hypertensive renovascular disease. N Engl J Med. 1975 Jul 31; 293(5):216-21.
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  225. Adelstein SJ, Jansen C, Wagner HN. Report of the Inter-Society Commission for Heart Disease Resources. Optimal resource guidelines for radioactive tracer studies of the heart and circulation. Circulation. 1975 Jul; 52(1):A9-A22.
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  226. Adelstein SJ. Editorial: Guidelines for radioactive tracer studies of the heart and circulation. Report of the Inter-society Commission for Heart Disease Resources. Radiology. 1975 Jul; 116(1):229-30.
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  227. Order SE, Bloomer WD, Jones AG, Kaplan WD, Davis MA, Adelstein SJ, Hellman S. Radionuclide immunoglobulin lymphangiography: a case report. Cancer. 1975 Jun; 35(6):1487-92.
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  228. Bloomer WD, Adelstein SJ. Letter: Antineoplastic effect of iodine-125-labelled iododeoxyuridine. Int J Radiat Biol Relat Stud Phys Chem Med. 1975 May; 27(5):509-11.
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  229. Adelstein SJ, Jansen C, Wagner HN Jr. Optimal resource guidelines for radioactive tracer studies of the heart and circulation. Report of the Inter-Society Commission for Heart Disease Resources. Circulation. 1975; 52:A9-A22.
  230. Adelstein SJ. Guidelines for radioactive tracer studies of the heart and circulation. Report of the Inter-Society C0mmission for Heart Disease Resources. Radiology. 1975; 116:229-230.
  231. Mee LK, Adelstein SJ. Inactivation of ribonuclease S-peptide by the primary aqueous radicals. Radiat Res. 1974 Dec; 60(3):422-31.
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  232. Kinoshita M, Holman BL, Zimmerman RE, Adams DF, Adelstein SJ, Hollenberg NK. Regional intrarenal perfusion in man: an assessment with the scintillation camera. J Nucl Med. 1974 Sep; 15(9):775-81.
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  233. Holman BL, Adams DF, Jewitt D, Eldh P, Idoine J, Cohn PF, Gorlin R, Adelstein SJ. Measuring regional myocardial blood flow with 133Xe and the Anger camera. Radiology. 1974 Jul; 112(1):99-107.
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  234. McNeil BJ, Holman BL, Adelstein SJ. The scintigraphic definition of pulmonary embolism. JAMA. 1974 Feb 18; 227(7):753-6.
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  235. Treves S, Maltz DL, Adelstein SJ. Intracardiac Shunts. James AE Jr, Wagner HN Jr, Cooke RE, ed. Pediatric nuclear medicine. 1974.
  236. Adelstein SJ, Holman BL. Pulmonary scintigraphy. One of a series. Postgrad Med. 1973 Aug; 54(2):69-74.
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  237. Paraskos JA, Adelstein SJ, Smith RE, Rickman FD, Grossman W, Dexter L, Dalen JE. Late prognosis of acute pulmonary embolism. N Engl J Med. 1973 Jul 12; 289(2):55-8.
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  238. Davidson RL, Adelstein SJ, Oxman MN. Herpes simplex virus as a source of thymidine kinase for thymidine kinase-deficient mouse cells: suppression and reactivation of the viral enzyme. Proc Natl Acad Sci U S A. 1973 Jul; 70(7):1912-6.
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  239. Lisco H, Lisco E, Adelstein SJ, Banks HH. Cytogenetic studies on blood lymphocytes of four patients with fracture of the femur injected with tritiated thymidine (3HTdR). Int J Radiat Biol Relat Stud Phys Chem Med. 1973 Jul; 24(1):45-57.
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  240. Holman BL, Eldh P, Adams DF, Han MH, Poggenburg JK, Adelstein SJ. Evaluation of myocardial perfusion after intracoronary injection of radiopotassium. J Nucl Med. 1973 May; 14(5):274-8.
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  241. Adelstein SJ, Holman BL. Pulmonary scintigraphy. Postgrad Med. 1973; 54(2):69-74.
  242. Treves S, Strieder DJ, Adelstein SJ. Scintillation camera radiospirometry. Potchen EJ, McCready VR, ed. Progress in nuclear medicine: Regional pulmonary function in health and disease. 1973; 3:149-165.
  243. Adelstein SJ. The risk:benefit ratio in nuclear medicine. Hosp Pract. 1973; 8:141-149.
  244. Treves S, Strieder DJ, Adelstein SJ. Scintillation camera radiospirometry. Prog Nucl Med. 1973; 3:149-65.
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  245. Mee LK, Adelstein SJ, Stein G. Inactivation of ribonuclease by the primary aqueous radicals. Radiat Res. 1972 Dec; 52(3):588-602.
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  246. Adelstein SJ, Baldwin C, Kohn HI. Thymidine kinase in mouse liver: variations in soluble and mitochondrial-associated activity that are dependent on age, regeneration, starvation, and treatment with actinomycin D and puromycin. Dev Biol. 1971 Dec; 26(4):537-46.
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  247. Abrams HL, Adelstein SJ, Elliott LP, Ellis K, Greenspan RH, Judkins MP, Viamonte M Jr. Optimal radiologic facilities for examination of the chest and the cardiovascular system: Radiology study group. Report of the Inter-Society Commission for Heart Disease Resources. Circulation. 1971; 43:A135-A156.
  248. Adelstein SJ, Parker R, Wagner HN. First phase in objective evaluation of new diagnostic tests. Application to thyroid uptake of 131 I. Invest Radiol. 1970 May-Jun; 5(3):153-63.
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  249. Tashima LS, Adelstein SJ, Lyman CP. Radioglucose utilization by active, hibernating, and arousing ground squirrels. Am J Physiol. 1970 Jan; 218(1):303-9.
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  250. Adelstein SJ, Lyman CP. Pyrimidine nucleoside metabolism in mammalian cells: an in vitro comparison of two rodent species. Exp Cell Res. 1968 Apr; 50(1):104-16.
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  251. Mee LK, Adelstein SJ. Physical, chemical, and enzymatic properties of ribonuclease S-peptide x-irradiated in solution. Radiat Res. 1967 Sep; 32(1):93-111.
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  252. Adelstein SJ, Kohn HI. Failure of x-rays and actinomycin D to prevent the response of renal and hepatic thymidylate kinase to thymidine treatment in vivo. Biochim Biophys Acta. 1967 Mar 29; 138(1):163-8.
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  253. Awwad HK, Adelstein SJ, Potchen EJ, Dealy JB. The interconversion and reutilization of injected 75-Se-selenomethionine in the rat. J Biol Chem. 1967 Feb 10; 242(3):492-500.
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  254. Adelstein SJ, Lyman CP, O'Brien RC. . Cell proliferation kinetics in the tongue and intestinal epithelia of hibernating dormice (Glis glis). Mammalian hibernation III, Proceedings Third International Symposium on Natural Mammalian Hibernation. 1967; 398-401.
  255. Adelstein SJ, Manasek GB. X-irradiation of splenic lymphocytes. II. Differential incorporation of pyrimidine nucleotide precursors into DNA. Int J Radiat Biol Relat Stud Phys Chem Med. 1967; 12(6):593-5.
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  256. Adelstein SJ, Manasek GB. X-irradiation of splenic lymphocytes. I. Thymidine pools and radiothymidine incorporation into DNA. Int J Radiat Biol Relat Stud Phys Chem Med. 1967; 12(6):587-91.
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  257. Qawwad HK, Potchen EJ, Adelstein SJ, Dealy JB. Se75-selenomethionine incorporation into human plasma proteins and erythrocytes. Metabolism. 1966 Jul; 15(7):626-40.
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  258. Potchen EJ, Awwad HK, Adelstein SJ, Dealy JB. The thyroid uptake of selenium-75-selenomethionine: effect of L-thyroxine and thyroid stimulating hormone. J Nucl Med. 1966 Jun; 7(6):433-41.
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  259. Awwad HK, Potchen EJ, Adelstein SJ, Dealy JB. The regional distribution of Se75-selenomethionine in the rat. Metabolism. 1966 Apr; 15(4):370-8.
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  260. Manasek FJ, Adelstein SJ, Lyman CP. DNA-synthesis in irradiated lymphoid cells: effects on temperature on the dose-response curve. Int J Radiat Biol Relat Stud Phys Chem Med. 1966; 10(2):189-97.
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  261. Manasek FJ, Adelstein SJ, Lyman CP. The effects of hibernation on the in vitro synthesis of DNA by hamster lymphoid tissue. J Cell Physiol. 1965 Jun; 65(3):319-24.
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  262. ADELSTEIN SJ. COENZYME BINDING BY X-IRRADIATED GLUTAMATE AND LACTATE DEHYDROGENASE. Biochemistry. 1965 May; 4:891-6.
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  263. POTCHEN EJ, ADELSTEIN SJ, DEALY JB. RADIOISOTOPE LOCALIZATION OF THE OVERACTIVE HUMAN PARATHYROID. Am J Roentgenol Radium Ther Nucl Med. 1965 Apr; 93:955-61.
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  264. ADELSTEIN SJ, DEALY JB. HEMATOLOGIC RESPONSES TO HUMAN WHOLE BODY IRRADIATION; ANALYTIC APPROACHES TO BIOLOGIC DOSIMETRY. Am J Roentgenol Radium Ther Nucl Med. 1965 Apr; 93:927-34.
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  265. SMITH TW, ADELSTEIN SJ. THE RADIOLYSIS OF PANCREATIC RIBONUCLEASE: KINETIC AND OPTICAL PROPERTIES. Radiat Res. 1965 Jan; 24:119-32.
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  266. Adelstein SJ. Radiation-induced changes in biologically active macromolecules. Radiol Clin North Am. 1965; 3:181-195.
  267. ADELSTEIN SJ, LYMAN CP, O'BRIEN RC. VARIATIONS IN THE INCORPORATION OF THYMIDINE INTO THE DNA OF SOME RODENT SPECIES. Comp Biochem Physiol. 1964 Jun; 12:223-31.
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  268. ADELSTEIN SJ, MEE LK. RADIOLYSIS OF REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE IN AQUEOUS SOLUTION. Biochemistry. 1963 Nov-Dec; 2:1294-7.
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  269. ADELSTEIN SJ. Specific radioprotective effect of the mitochondrial matrix. Nature. 1962 Jul 14; 195:195-6.
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  270. ADELSTEIN SJ, BIGGS SL. The effects of x-irradiation on the enzymatic activity of nuclear DPN-pyrophosphorylase. Radiat Res. 1962 Apr; 16:422-31.
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  271. Adelstein SJ, Vallee BL. Copper. Comar CL, Bronner F, ed. Mineral metabolism. An advanced treatise. 1962; 2(B):371-401.
  272. ADELSTEIN SJ, VALLEE BL. Copper metabolism in man. N Engl J Med. 1961 Nov 2; 265:892-7 contd.
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  273. ADELSTEIN SJ, MEE LK. The effects of x-irradiation in solution on the kinetic, sedimentation and fluorescent properties of glutamic acid dehydrogenase. Biochem J. 1961 Aug; 80:406-14.
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  274. ADELSTEIN SJ, VALLEE BL. The inhibition of beef liver glutamic dehydrogenase by metal-binding agents. J Biol Chem. 1959 Apr; 234(4):824-8.
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  275. ADELSTEIN SJ, VALLEE BL. Zinc in beef liver glutamic dehydrogenase. J Biol Chem. 1958 Sep; 233(3):589-93.
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  276. ADELSTEIN SJ, COOMBS TL, VALLEE BL. Metalloenzymes and myocardial infarction. I. The relation between serum copper and ceruloplasmin and its catalytic activity. N Engl J Med. 1956 Jul 19; 255(3):105-9.
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  277. ADELSTEIN SJ, HERSHEY FB, LOOFBOUROW JR, SIZER IW. The stimulation of yeast growth and respiration by compounds produced by yeast cells irradiated with ultraviolet light. J Cell Physiol. 1952 Oct; 40(2):269-78.
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