Dennis Paul Orgill, M.D., PH.D.
|Title||Professor of Surgery|
|Institution||Brigham and Women's Hospital|
|Address||Div. of Plastic Surgery|
Brigham & Women's Hospital
Boston MA 02115
Available: 11/02/12, Expires: 01/30/14
The student will be asked to create a detailed research plan related to wound healing modalities in vivo (mice) and/or in vitro. The student will be expected to familiarize him or herself with the literature on the topic prior to developing an experimental plan. He or she will have the ability to learn basic cell culture techniques as well as histological processing and staining methods. Hands-on training with rodents will also be provided. Our research program fosters a collaborate environment in which students will have the opportunity to work with investigators and labs in the surrounding region. Lab meetings are held weekly on Wednesday mornings at 8:30am when students will have the chance to share the progress of their research and hear updates on projects by fellow researchers.
Ongoing investigations include:
-Investigating dose-dependent effects of platelet-rich plasma on fibroblasts metabolism
-Demonstration of the effectiveness and mechanisms of external volume expansion devices on the recipient site to fat grafting
-Effects of vibrations on fibroblast cultures
-In vitro investigation of embryonic extracts as immunomodulation and reprogramming agents and in vivo as a method to improve wound healing
-the role of mast cell proteases in wound healing
-use of dermal mesenchymal stem cells in wound healing.
Accelerated Regenerative Wound Healing with a Microarray Chamber Device and the Addition of Keratinocytes
Summer, 02/02/10 - 08/20/10
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