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Igor Elman, M.D.

TitleAssociate Professor of Psychiatry
InstitutionCambridge Health Alliance
DepartmentPsychiatry
AddressCentral Street Health Center
Cambridge Health Alliance
26 Central Street
Somerville MA 02143
Phone617/591-0919
Fax617/591-6054

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Elman I, Borsook D, Volkow ND. Pain and suicidality: Insights from reward and addiction neuroscience. Prog Neurobiol. 2013 Oct; 109:1-27.
    View in: PubMed
  2. Elman I, Gurvits TV, Tschibelu E, Spring JD, Lasko NB, Pitman RK. Neurological soft signs in individuals with pathological gambling. PLoS One. 2013; 8(4):e60885.
    View in: PubMed
  3. Borsook D, Edwards R, Elman I, Becerra L, Levine J. Pain and analgesia: The value of salience circuits. Prog Neurobiol. 2013 May; 104:93-105.
    View in: PubMed
  4. Kurbanov DB, Currie PJ, Simonson DC, Borsook D, Elman I. Effects of naltrexone on food intake and body weight gain in olanzapine-treated rats. J Psychopharmacol. 2012 Sep; 26(9):1244-51.
    View in: PubMed
  5. Elman I, Becerra L, Tschibelu E, Yamamoto R, George E, Borsook D. Yohimbine-induced amygdala activation in pathological gamblers: a pilot study. PLoS One. 2012; 7(2):e31118.
    View in: PubMed
  6. Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Schwarz AJ, Pendse G, Wallin D, Nutile L, Bishop J, George E, Elman I, Sunkaraneni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine. Neuroimage. 2012 Feb 15; 59(4):3762-73.
    View in: PubMed
  7. Langleben DD, Busch EL, O'Brien CP, Elman I. Depot naltrexone decreases rewarding properties of sugar in patients with opioid dependence. Psychopharmacology (Berl). 2012 Apr; 220(3):559-64.
    View in: PubMed
  8. Moulton EA, Elman I, Pendse G, Schmahmann J, Becerra L, Borsook D. Aversion-related circuitry in the cerebellum: responses to noxious heat and unpleasant images. J Neurosci. 2011 Mar 9; 31(10):3795-804.
    View in: PubMed
  9. Tschibelu E, Elman I. Gender differences in psychosocial stress and in its relationship to gambling urges in individuals with pathological gambling. J Addict Dis. 2011 Jan; 30(1):81-7.
    View in: PubMed
  10. Elman I, Zubieta JK, Borsook D. The missing p in psychiatric training: why it is important to teach pain to psychiatrists. Arch Gen Psychiatry. 2011 Jan; 68(1):12-20.
    View in: PubMed
  11. Elman I. Integrating psychology research and behavioral management. Psychol Res Behav Manag. 2011; 4:11-2.
    View in: PubMed
  12. Elman I, Tschibelu E, Borsook D. Psychosocial stress and its relationship to gambling urges in individuals with pathological gambling. Am J Addict. 2010 Jul-Aug; 19(4):332-9.
    View in: PubMed
  13. Upadhyay J, Maleki N, Potter J, Elman I, Rudrauf D, Knudsen J, Wallin D, Pendse G, McDonald L, Griffin M, Anderson J, Nutile L, Renshaw P, Weiss R, Becerra L, Borsook D. Alterations in brain structure and functional connectivity in prescription opioid-dependent patients. Brain. 2010 Jul; 133(Pt 7):2098-114.
    View in: PubMed
  14. Elman I, Lowen S, Frederick BB, Chi W, Becerra L, Pitman RK. Functional neuroimaging of reward circuitry responsivity to monetary gains and losses in posttraumatic stress disorder. Biol Psychiatry. 2009 Dec 15; 66(12):1083-90.
    View in: PubMed
  15. Yamamoto R, Ariely D, Chi W, Langleben DD, Elman I. Gender differences in the motivational processing of babies are determined by their facial attractiveness. PLoS One. 2009; 4(6):e6042.
    View in: PubMed
  16. Jarvis K, DelBello MP, Mills N, Elman I, Strakowski SM, Adler CM. Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders. J Child Adolesc Psychopharmacol. 2008 Dec; 18(6):557-63.
    View in: PubMed
  17. Rott D, Langleben DD, Elman I. Cocaine decreases plasma insulin concentrations in non-diabetic subjects: a randomized double-blind study. Diabet Med. 2008 Apr; 25(4):510-1.
    View in: PubMed
  18. Hopper JW, Pitman RK, Su Z, Heyman GM, Lasko NB, Macklin ML, Orr SP, Lukas SE, Elman I. Probing reward function in posttraumatic stress disorder: expectancy and satisfaction with monetary gains and losses. J Psychiatr Res. 2008 Aug; 42(10):802-7.
    View in: PubMed
  19. Elman I, Chi WH, Gurvits TV, Ryan ET, Lasko NB, Lukas SE, Pitman RK. Impaired reproduction of three-dimensional objects by cocaine-dependent subjects. J Neuropsychiatry Clin Neurosci. 2008; 20(4):478-84.
    View in: PubMed
  20. Langleben DD, Ruparel K, Elman I, Busch-Winokur S, Pratiwadi R, Loughead J, O'Brien CP, Childress AR. Acute effect of methadone maintenance dose on brain FMRI response to heroin-related cues. Am J Psychiatry. 2008 Mar; 165(3):390-4.
    View in: PubMed
  21. Yamamoto RT, Karlsgodt KH, Rott D, Lukas SE, Elman I. Effects of perceived cocaine availability on subjective and objective responses to the drug. Subst Abuse Treat Prev Policy. 2007; 2:30.
    View in: PubMed
  22. Elman I, Borsook D, Lukas SE. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology. 2006 Oct; 31(10):2091-120.
    View in: PubMed
  23. Langleben DD, Monterosso J, Elman I, Ash B, Krikorian G, Austin G. Effect of methylphenidate on Stroop Color-Word task performance in children with attention deficit hyperactivity disorder. Psychiatry Res. 2006 Mar 30; 141(3):315-20.
    View in: PubMed
  24. Borsook D, Becerra L, Carlezon WA, Shaw M, Renshaw P, Elman I, Levine J. Reward-aversion circuitry in analgesia and pain: implications for psychiatric disorders. Eur J Pain. 2007 Jan; 11(1):7-20.
    View in: PubMed
  25. Elman I, Ariely D, Mazar N, Aharon I, Lasko NB, Macklin ML, Orr SP, Lukas SE, Pitman RK. Probing reward function in post-traumatic stress disorder with beautiful facial images. Psychiatry Res. 2005 Jun 30; 135(3):179-83.
    View in: PubMed
  26. Elman I, Lukas SE. Effects of cortisol and cocaine on plasma prolactin and growth hormone levels in cocaine-dependent volunteers. Addict Behav. 2005 May; 30(4):859-64.
    View in: PubMed
  27. Makris N, Gasic GP, Seidman LJ, Goldstein JM, Gastfriend DR, Elman I, Albaugh MD, Hodge SM, Ziegler DA, Sheahan FS, Caviness VS, Tsuang MT, Kennedy DN, Hyman SE, Rosen BR, Breiter HC. Decreased absolute amygdala volume in cocaine addicts. Neuron. 2004 Nov 18; 44(4):729-40.
    View in: PubMed
  28. Hopper JW, Karlsgodt KH, Adler CM, Macklin EA, Lukas SE, Elman I. Effects of acute cortisol and cocaine administration on attention, recall and recognition task performance in individuals with cocaine dependence. Hum Psychopharmacol. 2004 Oct; 19(7):511-6.
    View in: PubMed
  29. Mitropoulou V, Goodman M, Sevy S, Elman I, New AS, Iskander EG, Silverman JM, Breier A, Siever LJ. Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizotypal personality disorder. Schizophr Res. 2004 Sep 1; 70(1):27-31.
    View in: PubMed
  30. Elman I, Rott D, Green AI, Langleben DD, Lukas SE, Goldstein DS, Breier A. Effects of pharmacological doses of 2-deoxyglucose on plasma catecholamines and glucose levels in patients with schizophrenia. Psychopharmacology (Berl). 2004 Nov; 176(3-4):369-75.
    View in: PubMed
  31. Elman I, Lukas S, Shoaf SE, Rott D, Adler C, Breier A. Effects of acute metabolic stress on the peripheral vasopressinergic system in schizophrenia. J Psychopharmacol. 2003 Sep; 17(3):317-23.
    View in: PubMed
  32. Karlsgodt KH, Lukas SE, Elman I. Psychosocial stress and the duration of cocaine use in non-treatment seeking individuals with cocaine dependence. Am J Drug Alcohol Abuse. 2003 Aug; 29(3):539-51.
    View in: PubMed
  33. Elman I, Lukas SE, Karlsgodt KH, Gasic GP, Breiter HC. Acute cortisol administration triggers craving in individuals with cocaine dependence. Psychopharmacol Bull. 2003; 37(3):84-9.
    View in: PubMed
  34. Langleben DD, Acton PD, Austin G, Elman I, Krikorian G, Monterosso JR, Portnoy O, Ridlehuber HW, Strauss HW. Effects of methylphenidate discontinuation on cerebral blood flow in prepubescent boys with attention deficit hyperactivity disorder. J Nucl Med. 2002 Dec; 43(12):1624-9.
    View in: PubMed
  35. Elman I, Goldstein DS, Green AI, Eisenhofer G, Folio CJ, Holmes CS, Pickar D, Breier A. Effects of risperidone on the peripheral noradrenegic system in patients with schizophrenia: a comparison with clozapine and placebo. Neuropsychopharmacology. 2002 Aug; 27(2):293-300.
    View in: PubMed
  36. Elman I, Karlsgodt KH, Gastfriend DR, Chabris CF, Breiter HC. Cocaine-primed craving and its relationship to depressive symptomatology in individuals with cocaine dependence. J Psychopharmacol. 2002 Jun; 16(2):163-7.
    View in: PubMed
  37. Adler CM, Malhotra AK, Elman I, Pickar D, Breier A. Amphetamine-induced dopamine release and post-synaptic specific binding in patients with mild tardive dyskinesia. Neuropsychopharmacology. 2002 Mar; 26(3):295-300.
    View in: PubMed
  38. Elman I, Karlsgodt KH, Gastfriend DR. Gender differences in cocaine craving among non-treatment-seeking individuals with cocaine dependence. Am J Drug Alcohol Abuse. 2001 May; 27(2):193-202.
    View in: PubMed
  39. Elman I, Krause S, Karlsgodt K, Schoenfeld DA, Gollub RL, Breiter HC, Gastfriend DR. Clinical outcomes following cocaine infusion in nontreatment-seeking individuals with cocaine dependence. Biol Psychiatry. 2001 Mar 15; 49(6):553-5.
    View in: PubMed
  40. Elman I, Goldstein DS, Adler CM, Shoaf SE, Breier A. Inverse relationship between plasma epinephrine and testosterone levels during acute glucoprivation in healthy men. Life Sci. 2001 Mar 9; 68(16):1889-98.
    View in: PubMed
  41. Elman I, D'Ambra MN, Krause S, Breiter H, Kane M, Morris R, Tuffy L, Gastfriend DR. Ultrarapid opioid detoxification: effects on cardiopulmonary physiology, stress hormones and clinical outcomes. Drug Alcohol Depend. 2001 Jan 1; 61(2):163-72.
    View in: PubMed
  42. Adler CM, Elman I, Weisenfeld N, Kestler L, Pickar D, Breier A. Effects of acute metabolic stress on striatal dopamine release in healthy volunteers. Neuropsychopharmacology. 2000 May; 22(5):545-50.
    View in: PubMed
  43. Elman I, Krause S, Breiter HC, Gollub RL, Heintges J, Baumgartner WA, Rosen BR, Gastfriend DR. The validity of self-reported drug use in non-treatment seeking individuals with cocaine dependence: correlation with biochemical assays. Am J Addict. 2000; 9(3):216-21.
    View in: PubMed
  44. Adler CM, Malhotra AK, Elman I, Goldberg T, Egan M, Pickar D, Breier A. Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia. Am J Psychiatry. 1999 Oct; 156(10):1646-9.
    View in: PubMed
  45. Elman I, Breiter HC, Gollub RL, Krause S, Kantor HL, Baumgartner WA, Gastfriend DR, Rosen BR. Depressive symptomatology and cocaine-induced pituitary-adrenal axis activation in individuals with cocaine dependence. Drug Alcohol Depend. 1999 Aug 2; 56(1):39-45.
    View in: PubMed
  46. Breier A, Su TP, Malhotra AK, Elman I, Adler CM, Weisenfeld NI, Pickar D. Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders. Neuropsychopharmacology. 1999 Apr; 20(4):340-5.
    View in: PubMed
  47. Breier AF, Malhotra AK, Su TP, Pinals DA, Elman I, Adler CM, Lafargue RT, Clifton A, Pickar D. Clozapine and risperidone in chronic schizophrenia: effects on symptoms, parkinsonian side effects, and neuroendocrine response. Am J Psychiatry. 1999 Feb; 156(2):294-8.
    View in: PubMed
  48. Elman I, Sokoloff L, Adler CM, Weisenfeld N, Breier A. The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers. Brain Res. 1999 Jan 9; 815(2):243-9.
    View in: PubMed
  49. Elman I, Goldstein DS, Eisenhofer G, Folio J, Malhotra AK, Adler CM, Pickar D, Breier A. Mechanism of peripheral noradrenergic stimulation by clozapine. Neuropsychopharmacology. 1999 Jan; 20(1):29-34.
    View in: PubMed
  50. Breier A, Kestler L, Adler C, Elman I, Wiesenfeld N, Malhotra A, Pickar D. Dopamine D2 receptor density and personal detachment in healthy subjects. Am J Psychiatry. 1998 Oct; 155(10):1440-2.
    View in: PubMed
  51. Elman I, Adler CM, Malhotra AK, Bir C, Pickar D, Breier A. Effect of acute metabolic stress on pituitary-adrenal axis activation in patients with schizophrenia. Am J Psychiatry. 1998 Jul; 155(7):979-81.
    View in: PubMed
  52. Breier A, Adler CM, Weisenfeld N, Su TP, Elman I, Picken L, Malhotra AK, Pickar D. Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach. Synapse. 1998 Jun; 29(2):142-7.
    View in: PubMed
  53. Bertolino A, Callicott JH, Elman I, Mattay VS, Tedeschi G, Frank JA, Breier A, Weinberger DR. Regionally specific neuronal pathology in untreated patients with schizophrenia: a proton magnetic resonance spectroscopic imaging study. Biol Psychiatry. 1998 May 1; 43(9):641-8.
    View in: PubMed
  54. Elman I, Sigler M, Kronenberg J, Lindenmayer JP, Doron A, Mendlovic S, Gaoni B. Characteristics of patients with schizophrenia successive to childhood attention deficit hyperactivity disorder (ADHD). Isr J Psychiatry Relat Sci. 1998; 35(4):280-6.
    View in: PubMed
  55. Breier A, Elman I, Goldstein DS. Norepinephrine and schizophrenia: a new hypothesis for antipsychotic drug action. Adv Pharmacol. 1998; 42:785-8.
    View in: PubMed
  56. Malhotra AK, Adler CM, Kennison SD, Elman I, Pickar D, Breier A. Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine. Biol Psychiatry. 1997 Oct 15; 42(8):664-8.
    View in: PubMed
  57. Malhotra AK, Pinals DA, Adler CM, Elman I, Clifton A, Pickar D, Breier A. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology. 1997 Sep; 17(3):141-50.
    View in: PubMed
  58. Elman I, Breier A. Effects of acute metabolic stress on plasma progesterone and testosterone in male subjects: relationship to pituitary-adrenocortical axis activation. Life Sci. 1997; 61(17):1705-12.
    View in: PubMed
  59. Elman I, Kronenberg J, Kaysar N, Gaoni B. [Hypothalamic-pituitary-adrenal dysfunction in adolescent girls with anorexia nervosa]. Harefuah. 1992 Jul; 123(1-2):42-4.
    View in: PubMed
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