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Keywords
Last Name
Institution

Michael William Donnino, M.D.

TitleAssociate Professor of Medicine
InstitutionBeth Israel Deaconess Medical Center
DepartmentMedicine
AddressBeth Israel Deaconess Medical Center
Emergecny Medicine - WCC2
One Deaconess Rd
Boston MA 02215
Phone617/754-2323
Fax617/754-2350

 Overview 
 overview
Dr. Michael Donnino is an attending physician in the Department of Emergency Medicine and Division of Pulmonary/Critical Care Medicine at Beth Israel Deaconess Medical Center. His clinical practice spans both the intensive care unit as well as the emergency department. Dr. Donnino was the first person in the country to train in a 6-year combined emergency medicine, internal medicine, and critical care program leading to board certification in all three areas. Dr. Donnino is also the Director of the Center for Resuscitation Science and Director of Critical Care in Emergency Medicine. Dr. Donnino’s research interests include clinical trials and clinical investigations in septic shock and cardiac arrest. In the field of cardiac arrest, Dr. Donnino is the lead investigator of a multi-center clinical trial evaluating the use of steroids in post-arrest shock and a multi-center trial evaluating thiamine as a metabolic resuscitator in septic shock. Other notable studies include an investigation in microcirculatory dysfunction post-arrest, an evaluation of the human metabolome in sepsis and post-cardiac arrest, and severity of illness scoring systems in post-cardiac arrest patients. Dr. Donnino is a member of the Advanced Cardiac Life Support (ACLS) Subcommittee at the American Heart Association and co-author of sections of the 2010 ACLS guidelines.


 Mentoring 
 completed student projects
Thiamine Deficiency in Critically Ill Patients with Sepsis
Summer, 06/18/07 - 08/10/07

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Girault C, Esquinas AM, Nicolas T, Berg KM, Donnino MW. Predicting noninvasive mechanical ventilation outcome: early may be too early! Respir Care. 2013 Feb; 58(2):e15-7.
    View in: PubMed
  2. Haynes JM, Borg BM, Thompson BR, Girault C, Esquinas AM, Nicolas T, Berg KM, Donnino MW. Expiratory reserve volume maneuver may be the preferred method for some patients during spirometry testing. Respir Care. 2013 Feb; 58(2):e14-7.
    View in: PubMed
  3. Schmelzle M, Splith K, Andersen LW, Kornek M, Schuppan D, Jones-Bamman C, Nowak M, Toxavidis V, Salhanick SD, Han L, Schulte am Esch J, Jonas S, Donnino MW, Robson SC. Increased plasma levels of microparticles expressing CD39 and CD133 in acute liver injury. Transplantation. 2013 Jan 15; 95(1):63-9.
    View in: PubMed
  4. Berg KM, Clardy P, Donnino MW. Noninvasive ventilation for acute respiratory failure: a review of the literature and current guidelines. Intern Emerg Med. 2012 Dec; 7(6):539-45.
    View in: PubMed
  5. Donnino MW, Miller JC, Bivens M, Cocchi MN, Salciccioli JD, Farris S, Gautam S, Cutlip D, Howell M. A pilot study examining the severity and outcome of the post-cardiac arrest syndrome: a comparative analysis of two geographically distinct hospitals. Circulation. 2012 Sep 18; 126(12):1478-83.
    View in: PubMed
  6. Andersen LW, Graver A, Donnino MW. Use of epinephrine for cardiac arrest prior to hospital arrival. JAMA. 2012 Jul 4; 308(1):29; author reply 30-1.
    View in: PubMed
  7. Chauhan A, Musunuru H, Donnino M, McCurdy MT, Chauhan V, Walsh M. The use of therapeutic hypothermia after cardiac arrest in a pregnant patient. Ann Emerg Med. 2012 Dec; 60(6):786-9.
    View in: PubMed
  8. Salciccioli JD, Cristia C, Chase M, Giberson T, Graver A, Gautam S, Cocchi MN, Donnino MW. Performance of SAPS II and SAPS III scores in postcardiac arrest. Minerva Anestesiol. 2012 Dec; 78(12):1341-7.
    View in: PubMed
  9. Chase M, Klasco RS, Joyce NR, Donnino MW, Wolfe RE, Shapiro NI. Predictors of bacteremia in emergency department patients with suspected infection. Am J Emerg Med. 2012 Nov; 30(9):1691-7.
    View in: PubMed
  10. Cocchi MN, Giberson B, Berg K, Salciccioli JD, Naini A, Buettner C, Akuthota P, Gautam S, Donnino MW. Coenzyme Q10 levels are low and associated with increased mortality in post-cardiac arrest patients. Resuscitation. 2012 Aug; 83(8):991-5.
    View in: PubMed
  11. Dugas AF, Mackenhauer J, Salciccioli JD, Cocchi MN, Gautam S, Donnino MW. Prevalence and characteristics of nonlactate and lactate expressors in septic shock. J Crit Care. 2012 Aug; 27(4):344-50.
    View in: PubMed
  12. Berg KM, Lang GR, Salciccioli JD, Bak E, Cocchi MN, Gautam S, Donnino MW. The rapid shallow breathing index as a predictor of failure of noninvasive ventilation for patients with acute respiratory failure. Respir Care. 2012 Oct; 57(10):1548-54.
    View in: PubMed
  13. Smithline HA, Donnino M, Greenblatt DJ. Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects. BMC Clin Pharmacol. 2012; 12:4.
    View in: PubMed
  14. Cox K, Cocchi MN, Salciccioli JD, Carney E, Howell M, Donnino MW. Prevalence and significance of lactic acidosis in diabetic ketoacidosis. J Crit Care. 2012 Apr; 27(2):132-7.
    View in: PubMed
  15. Becker LB, Aufderheide TP, Geocadin RG, Callaway CW, Lazar RM, Donnino MW, Nadkarni VM, Abella BS, Adrie C, Berg RA, Merchant RM, O'Connor RE, Meltzer DO, Holm MB, Longstreth WT, Halperin HR. Primary outcomes for resuscitation science studies: a consensus statement from the American Heart Association. Circulation. 2011 Nov 8; 124(19):2158-77.
    View in: PubMed
  16. Lucas JM, Cocchi MN, Salciccioli J, Stanbridge JA, Geocadin RG, Herman ST, Donnino MW. Neurologic recovery after therapeutic hypothermia in patients with post-cardiac arrest myoclonus. Resuscitation. 2012 Feb; 83(2):265-9.
    View in: PubMed
  17. Donnino MW, Cocchi MN, Salciccioli JD, Kim D, Naini AB, Buettner C, Akuthota P. Coenzyme Q10 levels are low and may be associated with the inflammatory cascade in septic shock. Crit Care. 2011; 15(4):R189.
    View in: PubMed
  18. Hunziker S, Bivens MJ, Cocchi MN, Miller J, Salciccioli J, Howell MD, Donnino MW. International validation of the out-of-hospital cardiac arrest score in the United States. Crit Care Med. 2011 Jul; 39(7):1670-4.
    View in: PubMed
  19. Cocchi MN, Miller J, Hunziker S, Carney E, Salciccioli J, Farris S, Joyce N, Zimetbaum P, Howell MD, Donnino MW. The association of lactate and vasopressor need for mortality prediction in survivors of cardiac arrest. Minerva Anestesiol. 2011 Nov; 77(11):1063-71.
    View in: PubMed
  20. Chase M, Joyce NR, Carney E, Salciccioli JD, Vinton D, Donnino MW, Edlow JA. ED patients with vertigo: can we identify clinical factors associated with acute stroke? Am J Emerg Med. 2012 May; 30(4):587-91.
    View in: PubMed
  21. Donnino MW, Rittenberger JC, Gaieski D, Cocchi MN, Giberson B, Peberdy MA, Abella BS, Bobrow BJ, Callaway C. The development and implementation of cardiac arrest centers. Resuscitation. 2011 Aug; 82(8):974-8.
    View in: PubMed
  22. Donnino M, Chauhan A, Walsh M. Therapeutic hypothermia after cardiac arrest. N Engl J Med. 2011 Jan 13; 364(2):187; author reply 187-8.
    View in: PubMed
  23. Cocchi MN, Giberson B, Donnino MW. Rapid rewarming of hypothermic patient using arctic sun device. J Intensive Care Med. 2012 Mar-Apr; 27(2):128-30.
    View in: PubMed
  24. Chadwell JB, Mitchell JR, Donnino M, Peterson C, Guentert P, Arnold C, Walsh M. Aspiration of radiolucent dentures in facial trauma: Case report. Ear Nose Throat J. 2010 Dec; 89(12):E1.
    View in: PubMed
  25. Miller JB, Walsh M, Patel PA, Rogan M, Arnold C, Maloney M, Donnino M. Pediatric cannabinoid hyperemesis: two cases. Pediatr Emerg Care. 2010 Dec; 26(12):919-20.
    View in: PubMed
  26. Vanden Hoek TL, Morrison LJ, Shuster M, Donnino M, Sinz E, Lavonas EJ, Jeejeebhoy FM, Gabrielli A. Part 12: cardiac arrest in special situations: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010 Nov 2; 122(18 Suppl 3):S829-61.
    View in: PubMed
  27. Peberdy MA, Callaway CW, Neumar RW, Geocadin RG, Zimmerman JL, Donnino M, Gabrielli A, Silvers SM, Zaritsky AL, Merchant R, Vanden Hoek TL, Kronick SL. Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010 Nov 2; 122(18 Suppl 3):S768-86.
    View in: PubMed
  28. Seigel TA, Cocchi MN, Salciccioli J, Shapiro NI, Howell M, Tang A, Donnino MW. Inadequacy of temperature and white blood cell count in predicting bacteremia in patients with suspected infection. J Emerg Med. 2012 Mar; 42(3):254-9.
    View in: PubMed
  29. Donnino MW, Carney E, Cocchi MN, Barbash I, Chase M, Joyce N, Chou PP, Ngo L. Thiamine deficiency in critically ill patients with sepsis. J Crit Care. 2010 Dec; 25(4):576-81.
    View in: PubMed
  30. Cocchi MN, Lucas JM, Salciccioli J, Carney E, Herman S, Zimetbaum P, Donnino MW. The role of cranial computed tomography in the immediate post-cardiac arrest period. Intern Emerg Med. 2010 Dec; 5(6):533-8.
    View in: PubMed
  31. Donnino MW, Cocchi MN, Smithline H, Carney E, Chou PP, Salciccioli J, Salciccoli J. Coronary artery bypass graft surgery depletes plasma thiamine levels. Nutrition. 2010 Jan; 26(1):133-6.
    View in: PubMed
  32. Donnino MW, Cocchi MN, Miller J, Fisher J. Cannabinoid hyperemesis: a case series. J Emerg Med. 2011 Apr; 40(4):e63-6.
    View in: PubMed
  33. Shapiro NI, Fisher C, Donnino M, Cataldo L, Tang A, Trzeciak S, Horowitz G, Wolfe RE. The feasibility and accuracy of point-of-care lactate measurement in emergency department patients with suspected infection. J Emerg Med. 2010 Jul; 39(1):89-94.
    View in: PubMed
  34. Callaway DW, Shapiro NI, Donnino MW, Baker C, Rosen CL. Serum lactate and base deficit as predictors of mortality in normotensive elderly blunt trauma patients. J Trauma. 2009 Apr; 66(4):1040-4.
    View in: PubMed
  35. Amesquita M, Cocchi MN, Donnino MW. Pulmonary embolism presenting as flank pain: a case series. J Emerg Med. 2012 May; 42(5):e97-100.
    View in: PubMed
  36. Donnino MW, Cocchi MN, Howell M, Clardy P, Talmor D, Cataldo L, Chase M, Al-Marshad A, Ngo L, Shapiro NI. Statin therapy is associated with decreased mortality in patients with infection. Acad Emerg Med. 2009 Mar; 16(3):230-4.
    View in: PubMed
  37. Wira CR, Becker JU, Martin G, Donnino MW. Anti-arrhythmic and vasopressor medications for the treatment of ventricular fibrillation in severe hypothermia: a systematic review of the literature. Resuscitation. 2008 Jul; 78(1):21-9.
    View in: PubMed
  38. Rogan M, Donnino M. Rhabdomyolysis. Intern Emerg Med. 2007 Dec; 2(4):291.
    View in: PubMed
  39. Miller JB, Donnino MW, Rogan M, Goyal N. Relative adrenal insufficiency in post-cardiac arrest shock is under-recognized. Resuscitation. 2008 Feb; 76(2):221-5.
    View in: PubMed
  40. Donnino MW, Goyal N, Terlecki TM, Donnino KF, Miller JB, Otero RM, Howell MD. Inadequate blood volume collected for culture: a survey of health care professionals. Mayo Clin Proc. 2007 Sep; 82(9):1069-72.
    View in: PubMed
  41. Donnino MW, Vega J, Miller J, Walsh M. Myths and misconceptions of Wernicke's encephalopathy: what every emergency physician should know. Ann Emerg Med. 2007 Dec; 50(6):715-21.
    View in: PubMed
  42. Cocchi MN, Kimlin E, Walsh M, Donnino MW. Identification and resuscitation of the trauma patient in shock. Emerg Med Clin North Am. 2007 Aug; 25(3):623-42, vii.
    View in: PubMed
  43. Howell MD, Donnino M, Clardy P, Talmor D, Shapiro NI. Occult hypoperfusion and mortality in patients with suspected infection. Intensive Care Med. 2007 Nov; 33(11):1892-9.
    View in: PubMed
  44. Donnino MW, Miller J, Goyal N, Loomba M, Sankey SS, Dolcourt B, Sherwin R, Otero R, Wira C. Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients. Resuscitation. 2007 Nov; 75(2):229-34.
    View in: PubMed
  45. Howell MD, Donnino MW, Talmor D, Clardy P, Ngo L, Shapiro NI. Performance of severity of illness scoring systems in emergency department patients with infection. Acad Emerg Med. 2007 Aug; 14(8):709-14.
    View in: PubMed
  46. Donnino MW, Clardy P, Talmor D. A central venous pressure goal of 8-12 mm Hg for all patients in septic shock. Crit Care Med. 2007 May; 35(5):1441.
    View in: PubMed
  47. Shapiro NI, Howell MD, Talmor D, Donnino M, Ngo L, Bates DW. Mortality in Emergency Department Sepsis (MEDS) score predicts 1-year mortality. Crit Care Med. 2007 Jan; 35(1):192-8.
    View in: PubMed
  48. Donnino MW, Miller J, Garcia AJ, McKee E, Walsh M. Distinctive acid-base pattern in Wernicke's encephalopathy. Ann Emerg Med. 2007 Dec; 50(6):722-5.
    View in: PubMed
  49. Wira C, Martin G, Stoner J, Margolis K, Donnino M. Application of normothermic cardiac arrest algorithms to hypothermic cardiac arrest in a canine model. Resuscitation. 2006 Jun; 69(3):509-16.
    View in: PubMed
  50. Donnino MW, Fisher J, Fischer J. Determining disease severity in severe sepsis and septic shock. Intern Emerg Med. 2006; 1(3):219-20.
    View in: PubMed
  51. Goyal N, Donnino MW, Vachhani R, Bajwa R, Ahmad T, Otero R. The utility of head computed tomography in the emergency department evaluation of syncope. Intern Emerg Med. 2006; 1(2):148-50.
    View in: PubMed
  52. Shapiro NI, Donnino MW. Sepsis: the changing times. Crit Care Med. 2005 Nov; 33(11):2700-1.
    View in: PubMed
  53. Cuschieri J, Rivers EP, Donnino MW, Katilius M, Jacobsen G, Nguyen HB, Pamukov N, Horst HM. Central venous-arterial carbon dioxide difference as an indicator of cardiac index. Intensive Care Med. 2005 Jun; 31(6):818-22.
    View in: PubMed
  54. Donnino M. Gastrointestinal beriberi: a previously unrecognized syndrome. Ann Intern Med. 2004 Dec 7; 141(11):898-9.
    View in: PubMed
  55. Donnino MW, Karriem-Norwood V, Rivers EP, Gupta A, Nguyen HB, Jacobsen G, McCord J, Tomlanovich MC. Prevalence of elevated troponin I in end-stage renal disease patients receiving hemodialysis. Acad Emerg Med. 2004 Sep; 11(9):979-81.
    View in: PubMed
  56. Rivers EP, Nguyen HB, Huang DT, Donnino M. Early goal-directed therapy. Crit Care Med. 2004 Jan; 32(1):314-5; author reply 315.
    View in: PubMed
  57. Rivers EP, Nguyen HB, Huang DT, Donnino MW. Critical care and emergency medicine. Curr Opin Crit Care. 2002 Dec; 8(6):600-6.
    View in: PubMed
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