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Scott Randy Frank, D.Phil.

TitleInstructor in Pediatrics
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressChildrens Hospital
GI Cell Biology, Enders, 620
300 Longwood Ave
Boston MA 02115
Phone617/919-4521

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Frank SR, Bell JH, Frödin M, Hansen SH. A ßPIX-PAK2 Complex Confers Protection against Scrib-Dependent and Cadherin-Mediated Apoptosis. Curr Biol. 2012 Oct 9; 22(19):1747-54.
    View in: PubMed
  2. Doehn U, Hauge C, Frank SR, Jensen CJ, Duda K, Nielsen JV, Cohen MS, Johansen JV, Winther BR, Lund LR, Winther O, Taunton J, Hansen SH, Frödin M. RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol Cell. 2009 Aug 28; 35(4):511-22.
    View in: PubMed
  3. Tzaban S, Massol RH, Yen E, Hamman W, Frank SR, Lapierre LA, Hansen SH, Goldenring JR, Blumberg RS, Lencer WI. The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity. J Cell Biol. 2009 May 18; 185(4):673-84.
    View in: PubMed
  4. Frank SR, Hansen SH. The PIX-GIT complex: a G protein signaling cassette in control of cell shape. Semin Cell Dev Biol. 2008 Jun; 19(3):234-44.
    View in: PubMed
  5. Frank SR, Adelstein MR, Hansen SH. GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover. EMBO J. 2006 May 3; 25(9):1848-59.
    View in: PubMed
  6. Shmuel M, Santy LC, Frank S, Avrahami D, Casanova JE, Altschuler Y. ARNO through its coiled-coil domain regulates endocytosis at the apical surface of polarized epithelial cells. J Biol Chem. 2006 May 12; 281(19):13300-8.
    View in: PubMed
  7. Taubert S, Gorrini C, Frank SR, Parisi T, Fuchs M, Chan HM, Livingston DM, Amati B. E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol Cell Biol. 2004 May; 24(10):4546-56.
    View in: PubMed
  8. Grandori C, Wu KJ, Fernandez P, Ngouenet C, Grim J, Clurman BE, Moser MJ, Oshima J, Russell DW, Swisshelm K, Frank S, Amati B, Dalla-Favera R, Monnat RJ. Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev. 2003 Jul 1; 17(13):1569-74.
    View in: PubMed
  9. Frank SR, Parisi T, Taubert S, Fernandez P, Fuchs M, Chan HM, Livingston DM, Amati B. MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep. 2003 Jun; 4(6):575-80.
    View in: PubMed
  10. Fernandez PC, Frank SR, Wang L, Schroeder M, Liu S, Greene J, Cocito A, Amati B. Genomic targets of the human c-Myc protein. Genes Dev. 2003 May 1; 17(9):1115-29.
    View in: PubMed
  11. Frank SR, Schroeder M, Fernandez P, Taubert S, Amati B. Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation. Genes Dev. 2001 Aug 15; 15(16):2069-82.
    View in: PubMed
  12. Amati B, Frank SR, Donjerkovic D, Taubert S. Function of the c-Myc oncoprotein in chromatin remodeling and transcription. Biochim Biophys Acta. 2001 Mar 21; 1471(3):M135-45.
    View in: PubMed
  13. Santy LC, Frank SR, Casanova JE. Expression and analysis of ARNO and ARNO mutants and their effects on ADP-ribosylation factor (ARF)-mediated actin cytoskeletal rearrangements. Methods Enzymol. 2001; 329:256-64.
    View in: PubMed
  14. Mukherjee S, Gurevich VV, Jones JC, Casanova JE, Frank SR, Maizels ET, Bader MF, Kahn RA, Palczewski K, Aktories K, Hunzicker-Dunn M. The ADP ribosylation factor nucleotide exchange factor ARNO promotes beta-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):5901-6.
    View in: PubMed
  15. Santy LC, Frank SR, Hatfield JC, Casanova JE. Regulation of ARNO nucleotide exchange by a PH domain electrostatic switch. Curr Biol. 1999 Oct 21; 9(20):1173-6.
    View in: PubMed
  16. Frank SR, Hatfield JC, Casanova JE. Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO. Mol Biol Cell. 1998 Nov; 9(11):3133-46.
    View in: PubMed
  17. Frank S, Upender S, Hansen SH, Casanova JE. ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6. J Biol Chem. 1998 Jan 2; 273(1):23-7.
    View in: PubMed
  18. Hansen SH, Frank SR, Casanova JE. Cloning and characterization of human phosphomannomutase, a mammalian homologue of yeast SEC53. Glycobiology. 1997 Sep; 7(6):829-34.
    View in: PubMed
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