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Ruth Ellen Tuomala, M.D.

TitleAssistant Professor of Obstetrics, Gynecology and Reproductive Biology
InstitutionBrigham and Women's Hospital
DepartmentObstetrics Gynecology & Repro. Bio.
AddressBrigham and Women's Hospital
Obstetrics & Gynecology
75 Francis St
Boston MA 02115
Phone617/732-5452
Fax617/232-6346

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Cape A, Tuomala RE, Taylor C, Puopolo KM. Peripartum bacteremia in the era of group B streptococcus prophylaxis. Obstet Gynecol. 2013 Apr; 121(4):812-8.
    View in: PubMed
  2. Fischer JH, Sarto GE, Habibi M, Kilpatrick SJ, Tuomala RE, Shier JM, Wollett L, Fischer PA, Khorana KS, Rodvold KA. Influence of body weight, ethnicity, oral contraceptives, and pregnancy on the pharmacokinetics of azithromycin in women of childbearing age. Antimicrob Agents Chemother. 2012 Feb; 56(2):715-24.
    View in: PubMed
  3. Camann W, Tuomala R. Antibiotic prophylaxis for cesarean delivery: always before skin incision! Int J Obstet Anesth. 2011 Jan; 20(1):1-2.
    View in: PubMed
  4. Livingston EG, Huo Y, Patel K, Brogly SB, Tuomala R, Scott GB, Bardeguez A, Stek A, Read JS. Mode of delivery and infant respiratory morbidity among infants born to HIV-1-infected women. Obstet Gynecol. 2010 Aug; 116(2 Pt 1):335-43.
    View in: PubMed
  5. Katz IT, Shapiro R, Li D, Govindarajulu U, Thompson B, Watts DH, Hughes MD, Tuomala R. Risk factors for detectable HIV-1 RNA at delivery among women receiving highly active antiretroviral therapy in the women and infants transmission study. J Acquir Immune Defic Syndr. 2010 May 1; 54(1):27-34.
    View in: PubMed
  6. Patel K, Shapiro DE, Brogly SB, Livingston EG, Stek AM, Bardeguez AD, Tuomala RE. Prenatal protease inhibitor use and risk of preterm birth among HIV-infected women initiating antiretroviral drugs during pregnancy. J Infect Dis. 2010 Apr 1; 201(7):1035-44.
    View in: PubMed
  7. Ouyang DW, Brogly SB, Lu M, Shapiro DE, Hershow RC, French AL, Leighty RM, Thompson B, Tuomala RE. Lack of increased hepatotoxicity in HIV-infected pregnant women receiving nevirapine compared with other antiretrovirals. AIDS. 2010 Jan 2; 24(1):109-14.
    View in: PubMed
  8. Paredes R, Cheng I, Kuritzkes DR, Tuomala RE. Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy. AIDS. 2010 Jan 2; 24(1):45-53.
    View in: PubMed
  9. Ouyang DW, Shapiro DE, Lu M, Brogly SB, French AL, Leighty RM, Thompson B, Tuomala RE, Hershow RC. Increased risk of hepatotoxicity in HIV-infected pregnant women receiving antiretroviral therapy independent of nevirapine exposure. AIDS. 2009 Nov 27; 23(18):2425-30.
    View in: PubMed
  10. Watts DH, Lu M, Thompson B, Tuomala RE, Meyer WA, Mendez H, Rich K, Hanson C, LaRussa P, Diaz C, Mofenson LM. Treatment interruption after pregnancy: effects on disease progression and laboratory findings. Infect Dis Obstet Gynecol. 2009; 2009:456717.
    View in: PubMed
  11. Bardeguez AD, Lindsey JC, Shannon M, Tuomala RE, Cohn SE, Smith E, Stek A, Buschur S, Cotter A, Bettica L, Read JS. Adherence to antiretrovirals among US women during and after pregnancy. J Acquir Immune Defic Syndr. 2008 Aug 1; 48(4):408-17.
    View in: PubMed
  12. Chen KT, Tuomala RE, Chu C, Huang ML, Watts DH, Zorrilla CD, Paul M, Hershow R, Larussa P. No association between antepartum serologic and genital tract evidence of herpes simplex virus-2 coinfection and perinatal HIV-1 transmission. Am J Obstet Gynecol. 2008 Apr; 198(4):399.e1-5.
    View in: PubMed
  13. Paredes R, Cheng I, Kuritzkes DR, Tuomala RE. High prevalence of primary lamivudine and nelfinavir resistance in HIV-1-infected pregnant women in the United States, 1998-2004. AIDS. 2007 Oct 1; 21(15):2103-6.
    View in: PubMed
  14. O'Rourke N, McElrath T, Baum R, Camann W, Tuomala R, Stuebe A, Kodali BS. Cesarean delivery in the interventional radiology suite: a novel approach to obstetric hemostasis. Anesth Analg. 2007 May; 104(5):1193-4, tables of contents.
    View in: PubMed
  15. Watts DH, Li D, Handelsman E, Tilson H, Paul M, Foca M, Vajaranant M, Diaz C, Tuomala R, Thompson B. Assessment of birth defects according to maternal therapy among infants in the Women and Infants Transmission Study. J Acquir Immune Defic Syndr. 2007 Mar 1; 44(3):299-305.
    View in: PubMed
  16. Bryant AS, Leighty RM, Shen X, Read JS, Brouwers P, Turpin DB, LaRussa PS, Pacheco-Acosta E, Paul ME, Vajaranant M, Tuomala RE. Predictors of repeat pregnancy among HIV-1-infected women. J Acquir Immune Defic Syndr. 2007 Jan 1; 44(1):87-92.
    View in: PubMed
  17. Brogly S, Read JS, Shapiro D, Stek A, Tuomala R. Participation of HIV-infected pregnant women in research in the United States. AIDS Res Hum Retroviruses. 2007 Jan; 23(1):51-3.
    View in: PubMed
  18. Unadkat JD, Wara DW, Hughes MD, Mathias AA, Holland DT, Paul ME, Connor J, Huang S, Nguyen BY, Watts DH, Mofenson LM, Smith E, Deutsch P, Kaiser KA, Tuomala RE. Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women. Antimicrob Agents Chemother. 2007 Feb; 51(2):783-6.
    View in: PubMed
  19. Stek AM, Mirochnick M, Capparelli E, Best BM, Hu C, Burchett SK, Elgie C, Holland DT, Smith E, Tuomala R, Cotter A, Read JS. Reduced lopinavir exposure during pregnancy. AIDS. 2006 Oct 3; 20(15):1931-9.
    View in: PubMed
  20. Minkoff H, Shen X, Xian LS, Watts DH, Leighty R, Hershow R, Palefsky J, Tuomala R, Neu N, Zorrilla CD, Paul M, Strickler H. Relationship of pregnancy to human papillomavirus among human immunodeficiency virus-infected women. Obstet Gynecol. 2006 Oct; 108(4):953-60.
    View in: PubMed
  21. Tuomala RE, Yawetz S. Protease Inhibitor Use During Pregnancy: Is There an Obstetrical Risk?. Journal of Infectious Diseases. 2006; 193:1191-1194.
  22. Tuomala RE, Yawetz S. Protease inhibitor use during pregnancy: is there an obstetrical risk? J Infect Dis. 2006 May 1; 193(9):1191-4.
    View in: PubMed
  23. Navas-Nacher EL, Read JS, Leighty RM, Tuomala RE, Zorrilla CD, Landesman S, Rosenblatt H, Hershow RC. Mode of delivery and postpartum HIV-1 disease progression: the Women and Infants Transmission Study. AIDS. 2006 Feb 14; 20(3):429-36.
    View in: PubMed
  24. Bardeguez AD, Lindsey JC, Shannon M, Cohn SE, Read JS, Smith E, Tuomala RE. Adherence to Antiretrovirals (ARVs) in US Women During and After Pregnancy. Poster S-241. 2006.
  25. Allen RH, Tuomala RE. Herpes simplex virus hepatitis causing acute liver dysfunction and thrombocytopenia in pregnancy. Obstet Gynecol. 2005 Nov; 106(5 Pt 2):1187-9.
    View in: PubMed
  26. Tuomala RE, Watts DH, Li D, Vajaranant M, Pitt J, Hammill H, Landesman S, Zorrilla C, Thompson B. Improved obstetric outcomes and few maternal toxicities are associated with antiretroviral therapy, including highly active antiretroviral therapy during pregnancy. J Acquir Immune Defic Syndr. 2005 Apr 1; 38(4):449-73.
    View in: PubMed
  27. Magder LS, Mofenson L, Paul ME, Zorrilla CD, Blattner WA, Tuomala RE, LaRussa P, Landesman S, Rich KC. Risk factors for in utero and intrapartum transmission of HIV. J Acquir Immune Defic Syndr. 2005 Jan 1; 38(1):87-95.
    View in: PubMed
  28. Genc MR, Vardhana S, Delaney ML, Onderdonk A, Tuomala R, Norwitz E, Witkin SS. Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women. Eur J Obstet Gynecol Reprod Biol. 2004 Oct 15; 116(2):152-6.
    View in: PubMed
  29. Genc MR, Onderdonk AB, Vardhana S, Delaney ML, Norwitz ER, Tuomala RE, Paraskevas LR, Witkin SS. Polymorphism in intron 2 of the interleukin-1 receptor antagonist gene, local midtrimester cytokine response to vaginal flora, and subsequent preterm birth. Am J Obstet Gynecol. 2004 Oct; 191(4):1324-30.
    View in: PubMed
  30. Charurat M, Blattner W, Hershow R, Buck A, Zorrilla CD, Watts DH, Paul M, Landesman S, Adeniyi-Jones S, Tuomala R. Changing trends in clinical AIDS presentations and survival among HIV-1-infected women. J Womens Health (Larchmt). 2004 Jul-Aug; 13(6):719-30.
    View in: PubMed
  31. Genc MR, Witkin SS, Delaney ML, Paraskevas LR, Tuomala RE, Norwitz ER, Onderdonk AB. A disproportionate increase in IL-1beta over IL-1ra in the cervicovaginal secretions of pregnant women with altered vaginal microflora correlates with preterm birth. Am J Obstet Gynecol. 2004 May; 190(5):1191-7.
    View in: PubMed
  32. Quayle AJ, Shah M, Cu-Uvin S, Politch JA, Chou C, Anderson DJ, Tuomala R, Crowley-Nowick PA, Duerr A. Implications of blood contamination for assessment of local cellular immunity in the endocervix. AIDS Res Hum Retroviruses. 2004 May; 20(5):543-6.
    View in: PubMed
  33. Minkoff H, Hershow R, Watts DH, Frederick M, Cheng I, Tuomala R, Pitt J, Zorrilla CD, Hammill H, Adeniyi-Jones SK, Thompson B. The relationship of pregnancy to human immunodeficiency virus disease progression. Am J Obstet Gynecol. 2003 Aug; 189(2):552-9.
    View in: PubMed
  34. Onderdonk AB, Lee ML, Lieberman E, Delaney ML, Tuomala RE. Quantitative microbiologic models for preterm delivery. J Clin Microbiol. 2003 Mar; 41(3):1073-9.
    View in: PubMed
  35. Tuomala RE, O'Driscoll PT, Bremer JW, Jennings C, Xu C, Read JS, Matzen E, Landay A, Zorrilla C, Blattner W, Charurat M, Anderson DJ. Cell-associated genital tract virus and vertical transmission of human immunodeficiency virus type 1 in antiretroviral-experienced women. J Infect Dis. 2003 Feb 1; 187(3):375-84.
    View in: PubMed
  36. Tuomala RE, Shapiro DE, Mofenson LM, Bryson Y, Culnane M, Hughes MD, O'Sullivan MJ, Scott G, Stek AM, Wara D, Bulterys M. Antiretroviral therapy during pregnancy and the risk of an adverse outcome. N Engl J Med. 2002 Jun 13; 346(24):1863-70.
    View in: PubMed
  37. Chen KT, Tuomala RE, Cohen AP, Eichenwald EC, Lieberman E. No increase in rates of early-onset neonatal sepsis by non-group B Streptococcus or ampicillin-resistant organisms. Am J Obstet Gynecol. 2001 Oct; 185(4):854-8.
    View in: PubMed
  38. Read JS, Tuomala R, Kpamegan E, Zorrilla C, Landesman S, Brown G, Vajaranant M, Hammill H, Thompson B. Mode of delivery and postpartum morbidity among HIV-infected women: the women and infants transmission study. J Acquir Immune Defic Syndr. 2001 Mar 1; 26(3):236-45.
    View in: PubMed
  39. Chen KT, Sell RL, Tuomala RE. Cost-effectiveness of elective cesarean delivery in human immunodeficiency virus-infected women(1). Obstet Gynecol. 2001 Feb; 97(2):161-8.
    View in: PubMed
  40. Panther LA, Tucker L, Xu C, Tuomala RE, Mullins JI, Anderson DJ. Genital tract human immunodeficiency virus type 1 (HIV-1) shedding and inflammation and HIV-1 env diversity in perinatal HIV-1 transmission. J Infect Dis. 2000 Feb; 181(2):555-63.
    View in: PubMed
  41. Stratton P, Gupta P, Riester K, Fox H, Zorrilla C, Tuomala R, Eriksen N, Vajaranant M, Minkoff H, Fowler MG. Cervical dysplasia on cervicovaginal Papanicolaou smear among HIV-1-infected pregnant and nonpregnant women. Women and Infants Transmission Study. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Mar 1; 20(3):300-7.
    View in: PubMed
  42. Stratton P, Tuomala RE, Abboud R, Rodriguez E, Rich K, Pitt J, Diaz C, Hammill H, Minkoff H. Obstetric and newborn outcomes in a cohort of HIV-infected pregnant women: a report of the women and infants transmission study. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Feb 1; 20(2):179-86.
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  43. Scott GB, Tuomala R. Combination antiretroviral therapy during pregnancy. AIDS. 1998 Dec 24; 12(18):2495-7.
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  44. Pitt J, Schluchter M, Jenson H, Kovacs A, LaRussa P, McIntosh K, Boyer P, Cooper E, Goldfarb J, Hammill H, Hodes D, Peavy H, Sperling R, Tuomala R, Shearer W. Maternal and perinatal factors related to maternal-infant transmission of HIV-1 in the P2C2 HIV study: the role of EBV shedding. Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV-1 Infection (P2C2 HIV) Study Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Dec 15; 19(5):462-70.
    View in: PubMed
  45. Miller K, Corcoran C, Armstrong C, Caramelli K, Anderson E, Cotton D, Basgoz N, Hirschhorn L, Tuomala R, Schoenfeld D, Daugherty C, Mazer N, Grinspoon S. Transdermal testosterone administration in women with acquired immunodeficiency syndrome wasting: a pilot study. J Clin Endocrinol Metab. 1998 Aug; 83(8):2717-25.
    View in: PubMed
  46. Kalish LA, Boyer K, Brown G, Burns D, Diaz C, Hanson C, Landesman S, Matzen E, Tuomala R. Cigarette smoking and maternal-child HIV transmission. Women and Infants Transmission Study Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 May 1; 18(1):86-9.
    View in: PubMed
  47. Anderson DJ, Politch JA, Tucker LD, Fichorova R, Haimovici F, Tuomala RE, Mayer KH. Quantitation of mediators of inflammation and immunity in genital tract secretions and their relevance to HIV type 1 transmission. AIDS Res Hum Retroviruses. 1998 Apr; 14 Suppl 1:S43-9.
    View in: PubMed
  48. Martin R, Boyer P, Hammill H, Peavy H, Platzker A, Settlage R, Shah A, Sperling R, Tuomala R, Wu M. Incidence of premature birth and neonatal respiratory disease in infants of HIV-positive mothers. The Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted Human Immunodeficiency Virus Infection Study Group. J Pediatr. 1997 Dec; 131(6):851-6.
    View in: PubMed
  49. Tuomala RE. Prevention of transmission. Pharmaceutical and obstetric approaches. Obstet Gynecol Clin North Am. 1997 Dec; 24(4):785-95.
    View in: PubMed
  50. Tuomala RE, Kalish LA, Zorilla C, Fox H, Shearer W, Landay A, Vermund SH, Landesman S, Burns D. Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study. Obstet Gynecol. 1997 Jun; 89(6):967-74.
    View in: PubMed
  51. Burns DN, Tuomala R, Chang BH, Hershow R, Minkoff H, Rodriguez E, Zorrilla C, Hammill H, Regan J. Vaginal colonization or infection with Candida albicans in human immunodeficiency virus-infected women during pregnancy and during the postpartum period. Women and Infants Transmission Study Group. Clin Infect Dis. 1997 Feb; 24(2):201-10.
    View in: PubMed
  52. Landesman SH, Kalish LA, Burns DN, Minkoff H, Fox HE, Zorrilla C, Garcia P, Fowler MG, Mofenson L, Tuomala R. Obstetrical factors and the transmission of human immunodeficiency virus type 1 from mother to child. The Women and Infants Transmission Study. N Engl J Med. 1996 Jun 20; 334(25):1617-23.
    View in: PubMed
  53. Riley LE, Tuomala RE, Heeren T, Greene MF. Low risk of post-cesarean section infection in insulin-requiring diabetic women. Diabetes Care. 1996 Jun; 19(6):597-600.
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  54. Mofenson LM, Rodriguez EM, Hershow R, Fox HE, Landesman S, Tuomala R, Diaz C, Daniels E, Brambilla D. Mycobacterium tuberculosis infection in pregnant and nonpregnant women infected with HIV in the Women and Infants Transmission Study. Arch Intern Med. 1995 May 22; 155(10):1066-72.
    View in: PubMed
  55. Khouri YF, McIntosh K, Cavacini L, Posner M, Pagano M, Tuomala R, Marasco WA. Vertical Transmission of HIV-1. Correlation with maternal viral load and plasma levels of CD4 binding site anti-gp120 antibodies. J Clin Invest. 1995 Feb; 95(2):732-7.
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  56. McGregor JA, Crombleholme WR, Newton E, Sweet RL, Tuomala R, Gibbs RS. Randomized comparison of ampicillin-sulbactam to cefoxitin and doxycycline or clindamycin and gentamicin in the treatment of pelvic inflammatory disease or endometritis. Obstet Gynecol. 1994 Jun; 83(6):998-1004.
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  57. Rich JD, Buck A, Tuomala RE, Kazanjian PH. Transmission of human immunodeficiency virus infection presumed to have occurred via female homosexual contact. Clin Infect Dis. 1993 Dec; 17(6):1003-5.
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  58. Riley LE, Tuomala RE. Bacillary angiomatosis in a pregnant patient with acquired immunodeficiency syndrome. Obstet Gynecol. 1992 May; 79(5 ( Pt 2)):818-9.
    View in: PubMed
  59. Phillips RS, Tuomala RE, Feldblum PJ, Schachter J, Rosenberg MJ, Aronson MD. The effect of cigarette smoking, Chlamydia trachomatis infection, and vaginal douching on ectopic pregnancy. Obstet Gynecol. 1992 Jan; 79(1):85-90.
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  60. Tuomala R. Human immunodeficiency virus education and screening of prenatal patients. Obstet Gynecol Clin North Am. 1990 Sep; 17(3):571-83.
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  61. Harger JH, Hsing AW, Tuomala RE, Gibbs RS, Mead PB, Eschenbach DA, Knox GE, Polk BF. Risk factors for preterm premature rupture of fetal membranes: a multicenter case-control study. Am J Obstet Gynecol. 1990 Jul; 163(1 Pt 1):130-7.
    View in: PubMed
  62. Bengtson JM, VanMarter LJ, Barss VA, Greene MF, Tuomala RE, Epstein MF. Pregnancy outcome after premature rupture of the membranes at or before 26 weeks' gestation. Obstet Gynecol. 1989 Jun; 73(6):921-7.
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  63. Souney PF, Fisher S, Tuomala RE, Polk BF, Simpson C. Plasma and tissue concentrations of ceforanide and cefazolin in women undergoing hysterectomy. Chemotherapy. 1988; 34(3):185-90.
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  64. Sachs BP, Tuomala R, Frigoletto F. Acquired immunodeficiency syndrome: suggested protocol for counseling and screening in pregnancy. Obstet Gynecol. 1987 Sep; 70(3 Pt 1):408-11.
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  65. Sachs BP, Acker D, Tuomala R, Brown E. The incidence of symptomatic intracranial hemorrhage in term appropriate-for-gestation-age infants. Clin Pediatr (Phila). 1987 Jul; 26(7):355-8.
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  66. Saltzman DH, Eron LJ, Tuomala RE, Protomastro LJ, Sites JG. Single-dose antibiotic prophylaxis in high-risk patients undergoing cesarean section. A comparative trial. J Reprod Med. 1986 Aug; 31(8):709-12.
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  67. Goodman HM, Tuomala RE, Leavitt T. Actinomycotic pelvic inflammatory disease simulating malignancy. J Reprod Med. 1986 Jul; 31(7):625-8.
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  68. Tuomala RE, Fischer SG, Muñoz A, Souney PF, Steele L, Polk BF. A comparative trial of cefazolin and moxalactam as prophylaxis for preventing infection after abdominal hysterectomy. Obstet Gynecol. 1985 Sep; 66(3):372-6.
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  69. Ross MG, Mintz MC, Tuomala R, Frigoletto FD. The diagnosis of puerperal ovarian vein thrombophlebitis by computed axial tomography scan. Obstet Gynecol. 1983 Jul; 62(1):131-3.
    View in: PubMed
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