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Jeffrey Arthur Linder, M.D.

TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
1620 Tremont Street, BC-3-2X
Div. of General Medicine & Primary Care
Boston MA 02120
Phone617/525-6654
Fax617/732-7072

 Overview 
 overview
I am a general internist and primary care clinician-investigator at Brigham and Women’s Hospital and Harvard Medical School and see my overarching goal as improving primary care in the United States.

My research focuses on 2 principal topics: the care of ambulatory patients with acute respiratory infections – the number one symptomatic reason for seeking medical care in the United States – and the use of health information technology and electronic health records (EHRs) to improve ambulatory care. Please see below for a list of research publications, editorials, meeting proceedings, book chapters, and patient educational materials.

For teaching, I precept BWH Medical Residents in The Phyllis Jen Center for Primary Care. I teach Medical Students and Residents when I serve on the General Medical Service and supervise medical students in their core ambulatory rotation. I was a Conference Leader in the HMS Clinical Epidemiology and Population Health Course from 2007 to 2011. I currently Co-Direct the HMS first-year Pursuing Inquiry in Medicine Course and am the HMS Fellowship in General Medicine and Primary Care Site Director at BWH.

Administratively, for Partners HealthCare, I serve on the Longitudinal Medical Record (LMR) – the Partners Healthcare EHR – Expert Panel for Adult Primary Care and was a member of the LMR Executive Committee, representing research issues in the future direction of the LMR. At BWH, I am the Director of our Primary Care Practice Based Research Network.

Regionally, I served a 3-year term from 2007-2010 as the New England Regional President of the Society of General Internal Medicine. Nationally, I was on the Physicians Consortium for Performance Improvement Measures Implementation and Evaluation Advisory Committee and, from 2009-2012 was on the Agency for Healthcare Research and Quality Practice Based Research Network National Steering Committee. My primary care practice is at The Phyllis Jen Center for Primary Care where I provide preventive, acute, and chronic care for my primary care patients.


 Mentoring 
 current student opportunities
Available: 08/01/12, Expires: 09/30/14

To design, implement, and evaluate novel electronic health record functionality, informed by behavioral economic principles, that helps doctors avoid inappropriate antibiotic prescribing for patients with acute respiratory infections. Medical students could potentially become involved with any stage of the project including assisting with background work; the design, implementation, and evaluation of the intervention; or general assistance. Medical students will be exposed to a broad range of general and specific concepts including clinical research, practice-based research, electronic health records, information systems, informatics, primary care, behavior change, epidemiology, biostatistics, and behavioral economics.

Available: 11/03/10, Expires: 07/01/14

This project is using focus groups and quality improvement techniques to decrease the antibiotic prescribing rate for acute bronchitis to near zero percent in BWH primary care practices. We will be monitoring patients prospectively and retrospectively to identify outcomes and adverse events. Participating medical students can become involved at any stage of the project including design, patient enrollment, chart review, data entry, data analysis and intervention implementation.

Available: 08/01/12, Expires: 07/01/14

The student will work with Dr. Linder or other collaborator in the Brigham and Women's Primary Care Practice Based Research Network to identify and address a question related to primary care. Potential areas within primary care include epidemiology; clinical decision-making; quality of care; outcomes; patient preferences; use of health information technology and electronic health records; or others. The student may use local billing or administrative data; electronic health record data; publically-available data; or primary data collection, if appropriate.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Barnett ML, Linder JA. Antibiotic prescribing to adults with sore throat in the United States, 1997-2010. JAMA Intern Med. 2014 Jan 1; 174(1):138-40.
    View in: PubMed
  2. Linder JA. In: Bope ET and Kellerman RD, eds. Conn’s Current Therapy 2014. Influenza. 2014; 120-2.
  3. Mishuris RG, Linder JA. Electronic health records and the increasing complexity of medical practice. J Gen Intern Med. 2013 Nov; 28(11):1393.
    View in: PubMed
  4. Whaley LE, Businger AC, Dempsey PP, Linder JA. Visit complexity, diagnostic uncertainty, and antibiotic prescribing for acute cough in primary care: a retrospective study. BMC Fam Pract. 2013; 14:120.
    View in: PubMed
  5. Kruse GR, Chang Y, Kelley JH, Linder JA, Einbinder JS, Rigotti NA. Healthcare system effects of pay-for-performance for smoking status documentation. Am J Manag Care. 2013 Jul; 19(7):554-61.
    View in: PubMed
  6. Persell SD, Friedberg MW, Meeker D, Linder JA, Fox CR, Goldstein NJ, Shah PD, Knight TK, Doctor JN. Use of behavioral economics and social psychology to improve treatment of acute respiratory infections (BEARI): rationale and design of a cluster randomized controlled trial [1RC4AG039115-01] - study protocol and baseline practice and provider characteristics. BMC Infect Dis. 2013; 13:290.
    View in: PubMed
  7. Linder JA, Rigotti NA, Brawarsky P, Kontos EZ, Park ER, Klinger EV, Marinacci L, Li W, Haas JS. Use of practice-based research network data to measure neighborhood smoking prevalence. Prev Chronic Dis. 2013; 10:E84.
    View in: PubMed
  8. Mishuris RG, Linder JA. Electronic health records and the increasing complexity of medical practice: "it never gets easier, you just go faster". J Gen Intern Med. 2013 Apr; 28(4):490-2.
    View in: PubMed
  9. Linder JA. Antibiotic Prescribing for Acute Respiratory Infections-Success That's Way Off the Mark: Comment on "A Cluster Randomized Trial of Decision Support Strategies for Reducing Antibiotic Use in Acute Bronchitis". JAMA Intern Med. 2013 Feb 25; 173(4):273-5.
    View in: PubMed
  10. Linder JA. In: Bope ET and Kellerman RD, eds. Conn’s Current Therapy 2013. Influenza. 2013; 105-108.
  11. Frank JW, Ayanian JZ, Linder JA. Management of substance use disorders in ambulatory care in the United States, 2001-2009. Arch Intern Med. 2012 Dec 10; 172(22):1759-60.
    View in: PubMed
  12. Linder JA. Vitamin D and the cure for the common cold. JAMA. 2012 Oct 3; 308(13):1375-6.
    View in: PubMed
  13. Samal L, Linder JA. The primary care perspective on routine urine dipstick screening to identify patients with albuminuria. Clin J Am Soc Nephrol. 2013 Jan; 8(1):131-5.
    View in: PubMed
  14. Kruse GR, Kelley JH, Linder JA, Park ER, Rigotti NA. Implementation of an electronic health record-based care management system to improve tobacco treatment. J Gen Intern Med. 2012 Dec; 27(12):1690-6.
    View in: PubMed
  15. Linder JA, Schnipper JL, Middleton B. Method of electronic health record documentation and quality of primary care. J Am Med Inform Assoc. 2012 Nov 1; 19(6):1019-24.
    View in: PubMed
  16. Wroe PC, Finkelstein JA, Ray GT, Linder JA, Johnson KM, Rifas-Shiman S, Moore MR, Huang SS. Aging population and future burden of pneumococcal pneumonia in the United States. J Infect Dis. 2012 May 15; 205(10):1589-92.
    View in: PubMed
  17. Linder JA. In: Bope ET and Kellerman RD, eds. Conn’s Current Therapy 2012. Influenza. 2012; 107-109.
  18. Linder JA, Rigotti NA, Schneider LI, Kelley JH, Brawarsky P, Schnipper JL, Middleton B, Haas JS. Clinician characteristics and use of novel electronic health record functionality in primary care. J Am Med Inform Assoc. 2011 Dec; 18 Suppl 1:i87-90.
    View in: PubMed
  19. Samal L, Linder JA, Lipsitz SR, Hicks LS. Electronic health records, clinical decision support, and blood pressure control. Am J Manag Care. 2011 Sep; 17(9):626-32.
    View in: PubMed
  20. Huang SS, Johnson KM, Ray GT, Wroe P, Lieu TA, Moore MR, Zell ER, Linder JA, Grijalva CG, Metlay JP, Finkelstein JA. Healthcare utilization and cost of pneumococcal disease in the United States. Vaccine. 2011 Apr 18; 29(18):3398-412.
    View in: PubMed
  21. Samal L, Wright A, Wong BT, Linder JA, Bates DW. Leveraging electronic health records to support chronic disease management: the need for temporal data views. Inform Prim Care. 2011; 19(2):65-74.
    View in: PubMed
  22. Linder JA. In: Bope ET and Kellerman RD, eds. Conn’s Current Therapy 2011. Influenza. 2011; 90-93.
  23. Linder JA, Haas JS, Iyer A, Labuzetta MA, Ibara M, Celeste M, Getty G, Bates DW. Secondary use of electronic health record data: spontaneous triggered adverse drug event reporting. Pharmacoepidemiol Drug Saf. 2010 Dec; 19(12):1211-5.
    View in: PubMed
  24. Linder JA, Schnipper JL, Tsurikova R, Yu DT, Volk LA, Melnikas AJ, Palchuk MB, Olsha-Yehiav M, Middleton B. Electronic health record feedback to improve antibiotic prescribing for acute respiratory infections. Am J Manag Care. 2010 Dec; 16(12 Suppl HIT):e311-9.
    View in: PubMed
  25. Linder JA. Diagnosis of pertussis. JAMA. 2010 Dec 1; 304(21):2358; author reply 2358-9.
    View in: PubMed
  26. Schnipper JL, Linder JA, Palchuk MB, Yu DT, McColgan KE, Volk LA, Tsurikova R, Melnikas AJ, Einbinder JS, Middleton B. Effects of documentation-based decision support on chronic disease management. Am J Manag Care. 2010 Dec; 16(12 Suppl HIT):SP72-81.
    View in: PubMed
  27. Linder JA, Schnipper JL, Tsurikova R, Volk LA, Middleton B. Self-reported familiarity with acute respiratory infection guidelines and antibiotic prescribing in primary care. Int J Qual Health Care. 2010 Dec; 22(6):469-75.
    View in: PubMed
  28. Bourgeois FC, Linder J, Johnson SA, Co JP, Fiskio J, Ferris TG. Impact of a computerized template on antibiotic prescribing for acute respiratory infections in children and adolescents. Clin Pediatr (Phila). 2010 Oct; 49(10):976-83.
    View in: PubMed
  29. Horsky J, McColgan K, Pang JE, Melnikas AJ, Linder JA, Schnipper JL, Middleton B. Complementary methods of system usability evaluation: surveys and observations during software design and development cycles. J Biomed Inform. 2010 Oct; 43(5):782-90.
    View in: PubMed
  30. Linder J. Comparative efficacy of influenza vaccines. N Engl J Med. 2010 Jan 14; 362(2):180; author reply 180-1.
    View in: PubMed
  31. Linder JA. In: Bope ET, Rakel RE and Kellerman RD, eds. Conn’s Current Therapy 2010. Influenza. 2010; 88-91.
  32. Saleem JJ, Militello LG, Arbuckle N, Flanagan M, Haggstrom DA, Linder JA, Doebbeling BN. Provider perceptions of colorectal cancer screening clinical decision support at three benchmark institutions. AMIA Annu Symp Proc. 2009; 2009:558-62.
    View in: PubMed
  33. Linder JA, Rigotti NA, Schneider LI, Kelley JH, Brawarsky P, Haas JS. An electronic health record-based intervention to improve tobacco treatment in primary care: a cluster-randomized controlled trial. Arch Intern Med. 2009 Apr 27; 169(8):781-7.
    View in: PubMed
  34. Linder JA, Nieva HR, Blumentals WA. Antiviral and antibiotic prescribing for influenza in primary care. J Gen Intern Med. 2009 Apr; 24(4):504-10.
    View in: PubMed
  35. Friedberg MW, Mehrotra A, Linder JA. Reporting hospitals' antibiotic timing in pneumonia: adverse consequences for patients? Am J Manag Care. 2009 Feb; 15(2):137-44.
    View in: PubMed
  36. Linder JA, Kaleba EO, Kmetik KS. Using electronic health records to measure physician performance for acute conditions in primary care: empirical evaluation of the community-acquired pneumonia clinical quality measure set. Med Care. 2009 Feb; 47(2):208-16.
    View in: PubMed
  37. Linder JA, Schnipper JL, Tsurikova R, Yu T, Volk LA, Melnikas AJ, Palchuk MB, Olsha-Yehiav M, Middleton B. Documentation-based clinical decision support to improve antibiotic prescribing for acute respiratory infections in primary care: a cluster randomised controlled trial. Inform Prim Care. 2009; 17(4):231-40.
    View in: PubMed
  38. Linder JA. In: Rakel RE and Bope ET, eds. Conn’s Current Therapy 2009. Influenza. 2009; 90-3.
  39. McGreevy KM, Lipsitz SR, Linder JA, Rimm E, Hoel DG. Using median regression to obtain adjusted estimates of central tendency for skewed laboratory and epidemiologic data. Clin Chem. 2009 Jan; 55(1):165-9.
    View in: PubMed
  40. Schnipper JL, McColgan KE, McColgan KE, Linder JA, Yu T, Fiskio J, Tsurikova R, Volk LA, Palchuk M, Middleton B. Improving management of chronic diseases with documentation-based clinical decision support: results of a pilot study. AMIA Annu Symp Proc. 2008; 1050.
    View in: PubMed
  41. Linder JA. Evaluation and management of adult pharyngitis. Compr Ther. 2008 Fall-Winter; 34(3-4):196-203.
    View in: PubMed
  42. Linder JA. Editorial commentary: antibiotics for treatment of acute respiratory tract infections: decreasing benefit, increasing risk, and the irrelevance of antimicrobial resistance. Clin Infect Dis. 2008 Sep 15; 47(6):744-6.
    View in: PubMed
  43. Schnipper JL, Linder JA, Palchuk MB, Einbinder JS, Li Q, Postilnik A, Middleton B. "Smart Forms" in an Electronic Medical Record: documentation-based clinical decision support to improve disease management. J Am Med Inform Assoc. 2008 Jul-Aug; 15(4):513-23.
    View in: PubMed
  44. Linder JA, editor. Cold and Flu. A 10-Minute Consult with Harvard Medical School. 2008.
  45. Farwell WR, Linder JA, Jha AK. Trends in prostate-specific antigen testing from 1995 through 2004. Arch Intern Med. 2007 Dec 10; 167(22):2497-502.
    View in: PubMed
  46. Palchuk MB, Postilnik A, Olsha-Yehiav M, Linder JA, Schnipper JL, Li Q, Middleton B. User interface accelerators for clinical documentation in Smart Form. AMIA Annu Symp Proc. 2007; 1067.
    View in: PubMed
  47. Jung E, Schnipper JL, Li Q, Linder JA, Rose AF, Li R, Eskin MS, Housman D, Middleton B, Einbinder JS. The coronary artery disease quality dashboard: a chronic care disease management tool in an electronic health record. AMIA Annu Symp Proc. 2007; 999.
    View in: PubMed
  48. Melnikas AJ, Schnipper JL, Linder JA, Volk LA, Turovsky S, Middleton B. Can a "Smart Form" increase physicians' satisfactions with managing patient health behavior risks? Results of a physician satisfaction survey. AMIA Annu Symp Proc. 2007; 1047.
    View in: PubMed
  49. Linder J, Schnipper JL, Volk LA, Tsurikova R, Palchuk M, Olsha-Yehiav M, Melnikas AJ, Middleton B. Clinical decision support to improve antibiotic prescribing for acute respiratory infections: results of a pilot study. AMIA Annu Symp Proc. 2007; 468-72.
    View in: PubMed
  50. Linder JA, Jung E, Housman D, Eskin MS, Schnipper JL, Middleton B, Einbinder JS. The Acute Respiratory Infection Quality Dashboard: a performance measurement reporting tool in an electronic health record. AMIA Annu Symp Proc. 2007; 1035.
    View in: PubMed
  51. Linder JA. Improving care for acute respiratory infections: better systems, not better microbiology. Clin Infect Dis. 2007 Nov 1; 45(9):1189-91.
    View in: PubMed
  52. Linder JA, Ma J, Bates DW, Middleton B, Stafford RS. Electronic health record use and the quality of ambulatory care in the United States. Arch Intern Med. 2007 Jul 9; 167(13):1400-5.
    View in: PubMed
  53. Linder JA, Chan JC, Bates DW. Evaluation and treatment of pharyngitis in primary care practice: the difference between guidelines is largely academic. Arch Intern Med. 2006 Jul 10; 166(13):1374-9.
    View in: PubMed
  54. Linder JA, Chan JC, Bates DW. Appropriateness of antiviral prescribing for influenza in primary care: a retrospective analysis. J Clin Pharm Ther. 2006 Jun; 31(3):245-52.
    View in: PubMed
  55. Linder JA. Influenza-associated deaths among children. N Engl J Med. 2006 Mar 23; 354(12):1317-8; author reply 1317-8.
    View in: PubMed
  56. Linder JA, Rose AF, Palchuk MB, Chang F, Schnipper JL, Chan JC, Middleton B. Decision support for acute problems: the role of the standardized patient in usability testing. J Biomed Inform. 2006 Dec; 39(6):648-55.
    View in: PubMed
  57. Linder JA. Acute Bronchitis. Rakel RE and Bope ET, eds. Conn’s Current Therapy 2006. 2006; 319-321.
  58. Wiese J, Linder JA. The Tier II Head and Neck Examination. Saint-Frances Guide: Clinical Clerkships: The Answer Book. Bent S and Saint S, Eds. 2006; 227-242.
  59. Weise J, Linder JA. The Tier I Head and Neck Examination. Saint-Frances Guide: Clinical Clerkships: The Answer Book. Bent S and Saint S, Eds. 2006; 165-179.
  60. Olsha-Yehiav M, Einbinder JS, Jung E, Linder JA, Greim J, Li Q, Schnipper JL, Middleton B. Quality Dashboards: technical and architectural considerations of an actionable reporting tool for population management. AMIA Annu Symp Proc. 2006; 1052.
    View in: PubMed
  61. Linder JA, Schnipper JL, Einbinder JS, Li Q, Middleton B. Improving care for acute and chronic problems with Smart Forms and Quality Dashboards. AMIA Annual Symposium Proceedings. 2006; 1193.
  62. Linder JA, Schnipper JL, Tsurikova R, Melnikas AJ, Volk LA, Middleton B. Barriers to electronic health record use during patient visits. AMIA Annu Symp Proc. 2006; 499-503.
    View in: PubMed
  63. Postilnik A, Palchuk MB, Vashevko M, Rudelson B, Plaks N, Schnipper JL, Linder JA, Li Q, Middleton B. Smart Form framework as a foundation for clinical documentation platform. AMIA Annu Symp Proc. 2006; 1067.
    View in: PubMed
  64. Linder JA, Bates DW, Lee GM, Finkelstein JA. Antibiotic treatment of children with sore throat. JAMA. 2005 Nov 9; 294(18):2315-22.
    View in: PubMed
  65. Linder JA, Bates DW, Williams DH, Connolly MA, Middleton B. Acute infections in primary care: accuracy of electronic diagnoses and electronic antibiotic prescribing. J Am Med Inform Assoc. 2006 Jan-Feb; 13(1):61-6.
    View in: PubMed
  66. Linder JA, Bates DW, Platt R. Antivirals and antibiotics for influenza in the United States, 1995--2002. Pharmacoepidemiol Drug Saf. 2005 Aug; 14(8):531-6.
    View in: PubMed
  67. Linder JA, Huang ES, Steinman MA, Gonzales R, Stafford RS. Fluoroquinolone prescribing in the United States: 1995 to 2002. Am J Med. 2005 Mar; 118(3):259-68.
    View in: PubMed
  68. Olsha-Yehiav M, Palchuk MB, Chang FY, Taylor DP, Schnipper JL, Linder JA, Li Q, Middleton B. Smart Forms: building condition-specific documentation and decision support tools for ambulatory EHR. AMIA Annu Symp Proc. 2005; 1066.
    View in: PubMed
  69. Linder JA, Atlas SJ. Health-related quality of life in patients with sinusitis. Curr Allergy Asthma Rep. 2004 Nov; 4(6):490-5.
    View in: PubMed
  70. Linder JA. Health information technology as a tool to improve care for acute respiratory infections. Am J Manag Care. 2004 Oct; 10(10):661-2.
    View in: PubMed
  71. Linder JA, Singer DE. Health-related quality of life of adults with upper respiratory tract infections. J Gen Intern Med. 2003 Oct; 18(10):802-7.
    View in: PubMed
  72. Linder JA, Singer DE. Desire for antibiotics and antibiotic prescribing for adults with upper respiratory tract infections. J Gen Intern Med. 2003 Oct; 18(10):795-801.
    View in: PubMed
  73. Wilcox CM, Linder J. Prospective evaluation of droperidol on sphincter of Oddi motility. Gastrointest Endosc. 2003 Oct; 58(4):483-7.
    View in: PubMed
  74. Linder JA, Singer DE, Stafford RS. Association between antibiotic prescribing and visit duration in adults with upper respiratory tract infections. Clin Ther. 2003 Sep; 25(9):2419-30.
    View in: PubMed
  75. Linder JA, Singer DE, Ancker M, Atlas SJ. Measures of health-related quality of life for adults with acute sinusitis. A systematic review. J Gen Intern Med. 2003 May; 18(5):390-401.
    View in: PubMed
  76. Steinman MA, Gonzales R, Linder JA, Landefeld CS. Changing use of antibiotics in community-based outpatient practice, 1991-1999. Ann Intern Med. 2003 Apr 1; 138(7):525-33.
    View in: PubMed
  77. Linder JA, Stafford RS. Erythromycin-resistant group A streptococci. N Engl J Med. 2002 Aug 22; 347(8):614-5; author reply 614-5.
    View in: PubMed
  78. Linder JA, Sim I. Antibiotic treatment of acute bronchitis in smokers: a systematic review. J Gen Intern Med. 2002 Mar; 17(3):230-4.
    View in: PubMed
  79. Linder JA, Singer DE . Concern about anthrax among adults with respiratory illnesses. Infect Dis Clin Pract. 2002; 11(5):288-290.
  80. Linder JA, Stafford RS. Antibiotic treatment of adults with sore throat by community primary care physicians: a national survey, 1989-1999. JAMA. 2001 Sep 12; 286(10):1181-6.
    View in: PubMed
  81. Linder JA, Stafford RS. The diagnosis and treatment of cough. N Engl J Med. 2001 Apr 5; 344(14):1097; author reply 1098.
    View in: PubMed
  82. Linder JA, Tice JA. Betacarotene and sunscreen use. Lancet. 1999 Dec 18-25; 354(9196):2164.
    View in: PubMed
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