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Last Name
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Bradford Clark Dickerson, M.D.

TitleAssociate Professor of Neurology
InstitutionMassachusetts General Hospital
DepartmentNeurology
AddressMassachusetts General Hospital
Gerontology Research Unit, Suite 2691
149 13th Street
Charlestown MA 02129
Phone617/726-2241
Fax617/726-5760

 Overview 
 overview
My research seeks to understand the neuroanatomic and neurophysiologic substrates of memory function in health and disease. I use structural and functional neuroimaging tools to study healthy younger and older individuals and those with cognitive impairment, including Alzheimer's disease and frontotemporal dementias. I have identified in vivo anatomic and physiologic correlates of memory function, and have begun to translate some of these measures into potential biomarkers of Alzheimer's disease. In particular, I was the first to report the observation that some individuals with mild cognitive impairment, the first symptomatic phase of Alzheimer's disease prior to dementia, demonstrate hyperactivation of memory-related brain regions, which may be an indication of attempted physiologic compensation for pathologic change. We are currently working heavily in the area of frontotemporal dementia, language (both semantics and syntax), affective and social behavior, and are aiming to identify behavioral and brain imaging markers of abnormalities in these disorders as well. I hope that these markers will be useful for identifying individuals who would be candidates for clinical trials of novel therapies for Alzheimer's disease and related neurodegenerative disorders. I have recently begun a series of clinical research studies investigating the brain-behavioral basis of frontotemporal dementias, one aim of which will be to translate these cognitive-behavioral and imaging measures into biomarkers. I teach at a local and national level on the topics of behavioral neurology, memory function, Alzheimer's disease, and magnetic resonance imaging. I mentor students, research assistants, neurology and psychiatry residents and fellows, and neurology, psychiatry, and radiology junior faculty on research methods and career development. In my weekly clinic, I see patients with disorders of behavior and cognition (including many patients with neurodegenerative dementias). I seek to identify clinical problems that I can pursue through my research, and attempt to use the insights I gain through research to provide better clinical care. FInally, I take care of patients and supervise residents through a month of hospital service each year.


 Mentoring 
 current student opportunities
Available: 10/31/13, Expires: 10/31/14

We have a large existing dataset of neuroimaging data and behavioral and symptom measures in patients with various forms of dementia particularly including Frontotemporal Dementia and Primary Progressive Aphasia as well as early and late onset Alzheimer's disease. The student would work with Dr. Dickerson to develop a specific hypothesis and then would perform analyses of data and write up the manuscript.

Available: 09/09/12, Expires: 09/12/14

Perform a clinically oriented research project involving advancing our understanding of brain-behavior relationships in memory, cognition, language, social or affective behavior as it relates to brain structure and function in normal aging or patients with neurodegenerative diseases.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Dickerson BC, Wolk DA. Biomarker-based prediction of progression in MCI: Comparison of AD signature and hippocampal volume with spinal fluid amyloid-ß and tau. Front Aging Neurosci. 2013; 5:55.
    View in: PubMed
  2. Makris N, Preti MG, Wassermann D, Rathi Y, Papadimitriou GM, Yergatian C, Dickerson BC, Shenton ME, Kubicki M. Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography. Brain Imaging Behav. 2013 Sep; 7(3):335-52.
    View in: PubMed
  3. Heuer HW, Mirsky JB, Kong EL, Dickerson BC, Miller BL, Kramer JH, Boxer AL. Antisaccade task reflects cortical involvement in mild cognitive impairment. Neurology. 2013 Oct 1; 81(14):1235-43.
    View in: PubMed
  4. Lamarre AK, Rascovsky K, Bostrom A, Toofanian P, Wilkins S, Sha SJ, Perry DC, Miller ZA, Naasan G, Laforce R, Hagen J, Takada LT, Tartaglia MC, Kang G, Galasko D, Salmon DP, Farias ST, Kaur B, Olichney JM, Quitania Park L, Mendez MF, Tsai PH, Teng E, Dickerson BC, Domoto-Reilly K, McGinnis S, Miller BL, Kramer JH. Interrater reliability of the new criteria for behavioral variant frontotemporal dementia. Neurology. 2013 May 21; 80(21):1973-7.
    View in: PubMed
  5. Bakkour A, Morris JC, Wolk DA, Dickerson BC. The effects of aging and Alzheimer's disease on cerebral cortical anatomy: Specificity and differential relationships with cognition. Neuroimage. 2013 Aug 1; 76:332-44.
    View in: PubMed
  6. Wolk DA, Mancuso L, Kliot D, Arnold SE, Dickerson BC. Familiarity-based memory as an early cognitive marker of preclinical and prodromal AD. Neuropsychologia. 2013 May; 51(6):1094-102.
    View in: PubMed
  7. Whitwell JL, Tosakulwong N, Weigand SD, Senjem ML, Lowe VJ, Gunter JL, Boeve BF, Knopman DS, Dickerson BC, Petersen RC, Jack CR. Does amyloid deposition produce a specific atrophic signature in cognitively normal subjects? Neuroimage (Amst). 2013; 2:249-57.
    View in: PubMed
  8. Perez DL, Dickerson BC, McGinnis SM, Sapolsky D, Johnson K, Searl M, Daffner KR. You don't say: dynamic aphasia, another variant of primary progressive aphasia? J Alzheimers Dis. 2013 Jan 1; 34(1):139-44.
    View in: PubMed
  9. Crutch SJ, Schott JM, Rabinovici GD, Boeve BF, Cappa SF, Dickerson BC, Dubois B, Graff-Radford NR, Krolak-Salmon P, Lehmann M, Mendez MF, Pijnenburg Y, Ryan NS, Scheltens P, Shakespeare T, Tang-Wai DF, van der Flier WM, Bain L, Carrillo MC, Fox NC. Shining a light on posterior cortical atrophy. Alzheimers Dement. 2013 Jul; 9(4):463-5.
    View in: PubMed
  10. Quiroz YT, Stern CE, Reiman EM, Brickhouse M, Ruiz A, Sperling RA, Lopera F, Dickerson BC. Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers. J Neurol Neurosurg Psychiatry. 2013 May; 84(5):556-61.
    View in: PubMed
  11. Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, Tirado V, Munoz C, Reiman RA, Huentelman MJ, Alexander GE, Langbaum JB, Kosik KS, Tariot PN, Lopera F. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. Lancet Neurol. 2012 Dec; 11(12):1048-56.
    View in: PubMed
  12. Bickart KC, Hollenbeck MC, Barrett LF, Dickerson BC. Intrinsic amygdala-cortical functional connectivity predicts social network size in humans. J Neurosci. 2012 Oct 17; 32(42):14729-41.
    View in: PubMed
  13. Das SR, Pluta J, Mancuso L, Kliot D, Orozco S, Dickerson BC, Yushkevich PA, Wolk DA. Increased functional connectivity within medial temporal lobe in mild cognitive impairment. Hippocampus. 2013 Jan; 23(1):1-6.
    View in: PubMed
  14. Domoto-Reilly K, Sapolsky D, Brickhouse M, Dickerson BC. Naming impairment in Alzheimer's disease is associated with left anterior temporal lobe atrophy. Neuroimage. 2012 Oct 15; 63(1):348-55.
    View in: PubMed
  15. Touroutoglou A, Hollenbeck M, Dickerson BC, Feldman Barrett L. Dissociable large-scale networks anchored in the right anterior insula subserve affective experience and attention. Neuroimage. 2012 May 1; 60(4):1947-58.
    View in: PubMed
  16. Entis JJ, Doerga P, Barrett LF, Dickerson BC. A reliable protocol for the manual segmentation of the human amygdala and its subregions using ultra-high resolution MRI. Neuroimage. 2012 Apr 2; 60(2):1226-35.
    View in: PubMed
  17. Dickerson BC, Wolk DA. MRI cortical thickness biomarker predicts AD-like CSF and cognitive decline in normal adults. Neurology. 2012 Jan 10; 78(2):84-90.
    View in: PubMed
  18. Putcha D, Brickhouse M, O'Keefe K, Sullivan C, Rentz D, Marshall G, Dickerson B, Sperling R. Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults. J Neurosci. 2011 Nov 30; 31(48):17680-8.
    View in: PubMed
  19. Johnson KA, Dickerson BC. A tale of two tracers: the age of wisdom for dementia diagnosis? Neurology. 2011 Dec 6; 77(23):2008-9.
    View in: PubMed
  20. Poulin SP, Dautoff R, Morris JC, Barrett LF, Dickerson BC. Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity. Psychiatry Res. 2011 Oct 31; 194(1):7-13.
    View in: PubMed
  21. McGinnis SM, Brickhouse M, Pascual B, Dickerson BC. Age-related changes in the thickness of cortical zones in humans. Brain Topogr. 2011 Oct; 24(3-4):279-91.
    View in: PubMed
  22. Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep; 134(Pt 9):2456-77.
    View in: PubMed
  23. Förster S, Grimmer T, Miederer I, Henriksen G, Yousefi BH, Graner P, Wester HJ, Förstl H, Kurz A, Dickerson BC, Bartenstein P, Drzezga A. Regional expansion of hypometabolism in Alzheimer's disease follows amyloid deposition with temporal delay. Biol Psychiatry. 2012 May 1; 71(9):792-7.
    View in: PubMed
  24. Dickerson BC. Quantitating severity and progression in primary progressive aphasia. J Mol Neurosci. 2011 Nov; 45(3):618-28.
    View in: PubMed
  25. Wolk DA, Dunfee KL, Dickerson BC, Aizenstein HJ, DeKosky ST. A medial temporal lobe division of labor: insights from memory in aging and early Alzheimer disease. Hippocampus. 2011 May; 21(5):461-6.
    View in: PubMed
  26. Smith EE, Salat DH, Jeng J, McCreary CR, Fischl B, Schmahmann JD, Dickerson BC, Viswanathan A, Albert MS, Blacker D, Greenberg SM. Correlations between MRI white matter lesion location and executive function and episodic memory. Neurology. 2011 Apr 26; 76(17):1492-9.
    View in: PubMed
  27. Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell L. Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults. Neurology. 2011 Apr 19; 76(16):1395-402.
    View in: PubMed
  28. Bickart KC, Wright CI, Dautoff RJ, Dickerson BC, Barrett LF. Amygdala volume and social network size in humans. Nat Neurosci. 2011 Feb; 14(2):163-4.
    View in: PubMed
  29. Wolk DA, Dickerson BC. Fractionating verbal episodic memory in Alzheimer's disease. Neuroimage. 2011 Jan 15; 54(2):1530-9.
    View in: PubMed
  30. Dickerson BC. Primary progressive aphasia: New insights paving the way toward clinical research tools. Neurology. 2010 Aug 17; 75(7):582-3.
    View in: PubMed
  31. Sapolsky D, Bakkour A, Negreira A, Nalipinski P, Weintraub S, Mesulam MM, Caplan D, Dickerson BC. Cortical neuroanatomic correlates of symptom severity in primary progressive aphasia. Neurology. 2010 Jul 27; 75(4):358-66.
    View in: PubMed
  32. Dickerson BC. Advances in quantitative magnetic resonance imaging-based biomarkers for Alzheimer disease. Alzheimers Res Ther. 2010; 2(4):21.
    View in: PubMed
  33. Weierich MR, Kensinger EA, Munnell AH, Sass SA, Dickerson BC, Wright CI, Barrett LF. Older and wiser? An affective science perspective on age-related challenges in financial decision making. Soc Cogn Affect Neurosci. 2011 Apr; 6(2):195-206.
    View in: PubMed
  34. Dickerson BC, Wolk DA. Dysexecutive versus amnesic phenotypes of very mild Alzheimer's disease are associated with distinct clinical, genetic and cortical thinning characteristics. J Neurol Neurosurg Psychiatry. 2011 Jan; 82(1):45-51.
    View in: PubMed
  35. Moriguchi Y, Negreira A, Weierich M, Dautoff R, Dickerson BC, Wright CI, Barrett LF. Differential hemodynamic response in affective circuitry with aging: an FMRI study of novelty, valence, and arousal. J Cogn Neurosci. 2011 May; 23(5):1027-41.
    View in: PubMed
  36. Wolk DA, Dickerson BC. Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease. Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22):10256-61.
    View in: PubMed
  37. O'Brien JL, O'Keefe KM, LaViolette PS, DeLuca AN, Blacker D, Dickerson BC, Sperling RA. Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline. Neurology. 2010 Jun 15; 74(24):1969-76.
    View in: PubMed
  38. Zaitchik D, Walker C, Miller S, LaViolette P, Feczko E, Dickerson BC. Mental state attribution and the temporoparietal junction: an fMRI study comparing belief, emotion, and perception. Neuropsychologia. 2010 Jul; 48(9):2528-36.
    View in: PubMed
  39. Wang L, Negreira A, LaViolette P, Bakkour A, Sperling RA, Dickerson BC. Intrinsic interhemispheric hippocampal functional connectivity predicts individual differences in memory performance ability. Hippocampus. 2010 Mar; 20(3):345-51.
    View in: PubMed
  40. Sperling RA, Dickerson BC, Pihlajamaki M, Vannini P, LaViolette PS, Vitolo OV, Hedden T, Becker JA, Rentz DM, Selkoe DJ, Johnson KA. Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Med. 2010 Mar; 12(1):27-43.
    View in: PubMed
  41. Wang L, Laviolette P, O'Keefe K, Putcha D, Bakkour A, Van Dijk KR, Pihlajamäki M, Dickerson BC, Sperling RA. Intrinsic connectivity between the hippocampus and posteromedial cortex predicts memory performance in cognitively intact older individuals. Neuroimage. 2010 Jun; 51(2):910-7.
    View in: PubMed
  42. Dickerson BC, Eichenbaum H. The episodic memory system: neurocircuitry and disorders. Neuropsychopharmacology. 2010 Jan; 35(1):86-104.
    View in: PubMed
  43. Pihlajamäki M, O' Keefe K, Bertram L, Tanzi RE, Dickerson BC, Blacker D, Albert MS, Sperling RA. Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease. Alzheimer Dis Assoc Disord. 2010 Jan-Mar; 24(1):28-36.
    View in: PubMed
  44. Weierich MR, Wright CI, Negreira A, Dickerson BC, Barrett LF. Novelty as a dimension in the affective brain. Neuroimage. 2010 Feb 1; 49(3):2871-8.
    View in: PubMed
  45. Miller MI, Priebe CE, Qiu A, Fischl B, Kolasny A, Brown T, Park Y, Ratnanather JT, Busa E, Jovicich J, Yu P, Dickerson BC, Buckner RL. Collaborative computational anatomy: an MRI morphometry study of the human brain via diffeomorphic metric mapping. Hum Brain Mapp. 2009 Jul; 30(7):2132-41.
    View in: PubMed
  46. Dickerson BC. New frontiers in computational analysis of human hippocampal anatomy. Hippocampus. 2009 Jun; 19(6):507-9.
    View in: PubMed
  47. Van Leemput K, Bakkour A, Benner T, Wiggins G, Wald LL, Augustinack J, Dickerson BC, Golland P, Fischl B. Automated segmentation of hippocampal subfields from ultra-high resolution in vivo MRI. Hippocampus. 2009 Jun; 19(6):549-57.
    View in: PubMed
  48. Polli FE, Wright CI, Milad MR, Dickerson BC, Vangel M, Barton JJ, Rauch SL, Manoach DS. Hemispheric differences in amygdala contributions to response monitoring. Neuroreport. 2009 Mar 4; 20(4):398-402.
    View in: PubMed
  49. Jovicich J, Czanner S, Han X, Salat D, van der Kouwe A, Quinn B, Pacheco J, Albert M, Killiany R, Blacker D, Maguire P, Rosas D, Makris N, Gollub R, Dale A, Dickerson BC, Fischl B. MRI-derived measurements of human subcortical, ventricular and intracranial brain volumes: Reliability effects of scan sessions, acquisition sequences, data analyses, scanner upgrade, scanner vendors and field strengths. Neuroimage. 2009 May 15; 46(1):177-92.
    View in: PubMed
  50. Dickerson BC, Sperling RA. Large-scale functional brain network abnormalities in Alzheimer's disease: insights from functional neuroimaging. Behav Neurol. 2009; 21(1):63-75.
    View in: PubMed
  51. Bakkour A, Morris JC, Dickerson BC. The cortical signature of prodromal AD: regional thinning predicts mild AD dementia. Neurology. 2009 Mar 24; 72(12):1048-55.
    View in: PubMed
  52. Dickerson BC. Imaging biomarkers for drug development in Alzheimer's disease. Imaging in CNS drug development: Implications for disease and therapy (Borsook D, Hargreaves R, Bullmore E, Becerra L, eds). 2008; in press.
  53. Nandigam RN, Viswanathan A, Delgado P, Skehan ME, Smith EE, Rosand J, Greenberg SM, Dickerson BC. MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength. AJNR Am J Neuroradiol. 2009 Feb; 30(2):338-43.
    View in: PubMed
  54. Wonderlick JS, Ziegler DA, Hosseini-Varnamkhasti P, Locascio JJ, Bakkour A, van der Kouwe A, Triantafyllou C, Corkin S, Dickerson BC. Reliability of MRI-derived cortical and subcortical morphometric measures: effects of pulse sequence, voxel geometry, and parallel imaging. Neuroimage. 2009 Feb 15; 44(4):1324-33.
    View in: PubMed
  55. Jorge Jovicich, Randy Gollub, Bruce Fischl, Brad Dickerson. Reliability of automated segmentation of brain image data: Effects of field strength and upgrade. Neuroimage. 2008; in preparation.
  56. Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex. 2009 Mar; 19(3):497-510.
    View in: PubMed
  57. Dickerson BC. Mild cognitive impairment (invited module for Stanford End-of-Life Web Curriculum project). 2008.
  58. Dickerson BC. Functional MRI in neurodegenerative diseases: From scientific insights to clinical applications. Functional MRI techniques, Filippi M (ed). 2008; in press.
  59. King RD, Sikkel E, George T, Hynan LS, Kennedy DN, Dickerson BC. Characterization of Atrophic Changes in the Cerebral Cortex Using 2-D Fractal Dimensional Analysis . Neuroimage. 2008; submitted.
  60. Dickerson, BC. Pre-dementia diagnosis of Alzheimer’s disease: Translating clinicobiologic research into practice (invited review) . Current Psychiatry Reviews. 2008.
  61. Dickerson BC. Molecular neuroimaging of neurodegenerative dementias. Alzheimer's disease and related dementias (Budson AE, Kowall N, eds). 2008.
  62. Mueller SG, Dickerson BC. Atrophy accelerates with conversion from mild cognitive impairment to Alzheimer disease. Neurology. 2008 May 6; 70(19 Pt 2):1728-9.
    View in: PubMed
  63. Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL. The cortical signature of Alzheimer’s disease: Regionally-specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cerebral Cortex. 2008; in press.
  64. Miller SL, Celone K, DePeau K, Diamond E, Dickerson BC, Rentz D, Pihlajamäki M, Sperling RA. Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):2181-6.
    View in: PubMed
  65. Dickerson BC. The medial temporal lobe: Anatomy and clinical relevance. MGH Comprehensive Textbook of Psychiatry (Rausch S et al., eds). 2008; in press.
  66. Van Leemput K, Bakkour A, Benner T, Wiggins G, Wald LL, Augustinack J, Dickerson BC, Golland P, Fischl B. Model-based segmentation of hippocampal subfields in ultra-high resolution in vivo MRI. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):235-43.
    View in: PubMed
  67. Dickerson BC. Chronic behavior change. In: Greene HL, Mushlin SB, eds. Decision Making in Medicine: An algorithmic approach. 2008; in press.
  68. Smith EE, Egorova S, Blacker D, Killiany RJ, Muzikansky A, Dickerson BC, Tanzi RE, Albert MS, Greenberg SM, Guttmann CR. Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. Arch Neurol. 2008 Jan; 65(1):94-100.
    View in: PubMed
  69. Dickerson BC. Acute confusional states. In: Greene HL, Mushlin SB, eds. Decision Making in Medicine: An algorithmic approach. 2008; in press.
  70. Dickerson BC. Memory loss. In: Greene HL, Mushlin SB, eds. Decision Making in Medicine: An algorithmic approach. 2008; in press.
  71. Dickerson BC, Sperling RA. Functional abnormalities of the medial temporal lobe memory system in mild cognitive impairment and Alzheimer's disease: insights from functional MRI studies. Neuropsychologia. 2008; 46(6):1624-35.
    View in: PubMed
  72. Dickerson BC, Sperling RA. Functional MRI in mild cognitive impairment and Alzheimer's disease. Functional neuroimaging of dementia (Rombouts SARB, ed). 2007; in press.
  73. Dickerson BC, Sperling RA, Hyman BT, Albert MS, Blacker D. Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment. Arch Gen Psychiatry. 2007 Dec; 64(12):1443-50.
    View in: PubMed
  74. Fennema-Notestine C, Gamst AC, Quinn BT, Pacheco J, Jernigan TL, Thal L, Buckner R, Killiany R, Blacker D, Dale AM, Fischl B, Dickerson B, Gollub RL. Feasibility of multi-site clinical structural neuroimaging studies of aging using legacy data. Neuroinformatics. 2007; 5(4):235-45.
    View in: PubMed
  75. Mueller SG, Dickerson BC. Accelerating brain atrophy rates as patients with Alzheimer's disease progress from MCI to dementia (invited commentary). Neurology. 2007; in press.
  76. Diamond EL, Miller S, Dickerson BC, Atri A, DePeau K, Fenstermacher E, Pihlajamäki M, Celone K, Salisbury S, Gregas M, Rentz D, Sperling RA. Relationship of fMRI activation to clinical trial memory measures in Alzheimer disease. Neurology. 2007 Sep 25; 69(13):1331-41.
    View in: PubMed
  77. Dickerson BC, Feczko E, Augustinack JC, Pacheco J, Morris JC, Fischl B, Buckner RL. Differential effects of aging and Alzheimer's disease on medial temporal lobe cortical thickness and surface area. Neurobiol Aging. 2009 Mar; 30(3):432-40.
    View in: PubMed
  78. Feczko E, Augustinack JC, Fischl B, Dickerson BC. An MRI-based method for measuring volume, thickness and surface area of entorhinal, perirhinal, and posterior parahippocampal cortex. Neurobiol Aging. 2009 Mar; 30(3):420-31.
    View in: PubMed
  79. Miller SL, Fenstermacher E, Bates J, Blacker D, Sperling RA, Dickerson BC. Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline. J Neurol Neurosurg Psychiatry. 2008 Jun; 79(6):630-5.
    View in: PubMed
  80. Dickerson BC, Fenstermacher E, Salat DH, Wolk DA, Maguire RP, Desikan R, Pacheco J, Quinn BT, Van der Kouwe A, Greve DN, Blacker D, Albert MS, Killiany RJ, Fischl B. Detection of cortical thickness correlates of cognitive performance: Reliability across MRI scan sessions, scanners, and field strengths. Neuroimage. 2008 Jan 1; 39(1):10-8.
    View in: PubMed
  81. Dickerson BC. Advances in functional magnetic resonance imaging: technology and clinical applications. Neurotherapeutics. 2007 Jul; 4(3):360-70.
    View in: PubMed
  82. Dickerson BC. Advances in functional MRI: Technology and clinical applications (invited review). Neurotherapeutics. 2007; 4(3):360-370.
  83. Dickerson BC. The entorhinal cortex: an anatomical mediator of genetic vulnerability to Alzheimer's disease? Lancet Neurol. 2007 Jun; 6(6):471-3.
    View in: PubMed
  84. Wright CI, Dickerson BC, Feczko E, Negeira A, Williams D. A functional magnetic resonance imaging study of amygdala responses to human faces in aging and mild Alzheimer's disease. Biol Psychiatry. 2007 Dec 15; 62(12):1388-95.
    View in: PubMed
  85. Wright CI, Feczko E, Dickerson B, Williams D. Neuroanatomical correlates of personality in the elderly. Neuroimage. 2007 Mar; 35(1):263-72.
    View in: PubMed
  86. Dickerson BC, Miller SL, Greve DN, Dale AM, Albert MS, Schacter DL, Sperling RA. Prefrontal-hippocampal-fusiform activity during encoding predicts intraindividual differences in free recall ability: an event-related functional-anatomic MRI study. Hippocampus. 2007; 17(11):1060-70.
    View in: PubMed
  87. Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, Miller SL, DePeau K, Rentz DM, Selkoe DJ, Blacker D, Albert MS, Sperling RA. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. Journal of Neuroscience. 2006; 26(40):10222-10231.
  88. Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, Miller SL, DePeau K, Rentz DM, Selkoe DJ, Blacker D, Albert MS, Sperling RA. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J Neurosci. 2006 Oct 4; 26(40):10222-31.
    View in: PubMed
  89. Dickerson BC. Functional MRI in the early detection of dementias. Rev Neurol (Paris). 2006 Oct; 162(10):941-4.
    View in: PubMed
  90. Han X, Jovicich J, Salat D, van der Kouwe A, Quinn B, Czanner S, Busa E, Pacheco J, Albert M, Killiany R, Maguire P, Rosas D, Makris N, Dale A, Dickerson B, Fischl B. Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturer. Neuroimage. 2006 Aug 1; 32(1):180-94.
    View in: PubMed
  91. Dickerson BC. Functional magnetic resonance imaging of cholinergic modulation in mild cognitive impairment. Curr Opin Psychiatry. 2006 May; 19(3):299-306.
    View in: PubMed
  92. Desikan RS, Ségonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, Buckner RL, Dale AM, Maguire RP, Hyman BT, Albert MS, Killiany RJ. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006 Jul 1; 31(3):968-80.
    View in: PubMed
  93. Wright CI, Williams D, Feczko E, Barrett LF, Dickerson BC, Schwartz CE, Wedig MM. Neuroanatomical correlates of extraversion and neuroticism. Cereb Cortex. 2006 Dec; 16(12):1809-19.
    View in: PubMed
  94. Dickerson BC. Section editor, Neurology section (15 chapters). In: Greene HL, Mushlin SB, eds. Decision-making in medicine: An algorithmic approach. 2006.
  95. Dickerson BC, Holtzman D, Grant PE, Tian D. Case records of the Massachusetts General Hospital. Case 36-2005. A 61-year-old woman with seizure, disturbed gait, and altered mental status. N Engl J Med. 2005 Nov 24; 353(21):2271-80.
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  96. Dickerson BC, Salat DH, Greve DN, Chua EF, Rand-Giovannetti E, Rentz DM, Bertram L, Mullin K, Tanzi RE, Blacker D, Albert MS, Sperling RA. Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology. 2005 Aug 9; 65(3):404-11.
    View in: PubMed
  97. Dickerson BC, Sperling RA. Neuroimaging biomarkers for clinical trials of disease-modifying therapies in Alzheimer's disease. NeuroRx. 2005 Apr; 2(2):348-60.
    View in: PubMed
  98. Miller S, Celone K, DePeau K, Sperling R, Dickerson BC. Differential hippocampal activation during intentional encoding, detection of novelty, and recognition. Society for Neuroscience. 2005.
  99. Fenstermacher E*, Dickerson BC*, Fischl B, Makris N, Albert MS, Blacker D, Killiany RJ (* authors contributed equally). Longitudinal rate of hippocampal atrophy predicts clinical progression from the mildest phase of MCI to AD. American Academy of Neurology. 2005.
  100. Dickerson BC, Salat DH, Greve DN, Albert MS, Blacker D, Sperling RA. Memory-related medial temporal lobe activation in mild cognitive impairment prior to dementia: An fMRI study. American Academy of Neurology. 2005.
  101. Atri A, Locascio JJ, Lin JM, Yap L, Dickerson BC, Grodstein F, Irizarry MC, Growdon JH, Greenberg SM. Prevalence and effects of lobar microhemorrhages in early-stage dementia. Neurodegener Dis. 2005; 2(6):305-12.
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  102. Han X, Jovicich J, Salat D, van der Kouwe A, Quinn B, Czanner S, Pacheco J, Albert M, Killiany R, Maguire P, Rosas HD, Makris N, Dale A, Dickerson B*, Fischl B* (* authors contributed equally). Reliability of MRI-derived measurements of human cerebral cortical thickness: The effects of field strength, scanner upgrade and manufacturer. Organization for Human Brain Mapping. 2005.
  103. Fennema-Notestine C, Gollub R, Fischl B, Quinn B, Pacheco J, Dickerson BC. Feasibility of multi-site clinical structural neuroimaging studies of legacy data: Aging and Alzheimer's disease. Society for Neuroscience. 2005.
  104. Dickerson BC, Miller S, Fenstermacher E, Greve D, Dale A, Albert M, Sperling R. Regional brain activity during encoding that predicts free recall. Society for Neuroscience. 2005.
  105. Dickerson BC, Salat DH, Bates JF, Atiya M, Killiany RJ, Greve DN, Dale AM, Stern CE, Blacker D, Albert MS, Sperling RA. Medial temporal lobe function and structure in mild cognitive impairment. Ann Neurol. 2004 Jul; 56(1):27-35.
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  106. Dickerson BC, Goncharova I, Sullivan MP, Forchetti C, Wilson RS, Bennett DA, Beckett LA, deToledo-Morrell L. MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease. Neurobiol Aging. 2001 Sep-Oct; 22(5):747-54.
    View in: PubMed
  107. Goncharova II, Dickerson BC, Stoub TR, deToledo-Morrell L. MRI of human entorhinal cortex: a reliable protocol for volumetric measurement. Neurobiol Aging. 2001 Sep-Oct; 22(5):737-45.
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  108. de Toledo-Morrell L, Goncharova I, Dickerson B, Wilson RS, Bennett DA. From healthy aging to early Alzheimer's disease: in vivo detection of entorhinal cortex atrophy. Ann N Y Acad Sci. 2000 Jun; 911:240-53.
    View in: PubMed
  109. deToledo-Morrell L, Goncharova I, Dickerson B, Wilson RS, Bennett DA. From healthy aging to Alzheimer’s disease: in vivo detection of entorhinal cortex atrophy. Ann NY Acad Sci. 2000; 911:240-253.
  110. de Toledo-Morrell L, Dickerson B, Sullivan MP, Spanovic C, Wilson R, Bennett DA. Hemispheric differences in hippocampal volume predict verbal and spatial memory performance in patients with Alzheimer's disease. Hippocampus. 2000; 10(2):136-42.
    View in: PubMed
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