 Ronald Gary Tompkins, SC.D., M.D.
| Title | Sumner M. Redstone Professor of Surgery |
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| Institution | Massachusetts General Hospital |
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| Department | Surgery |
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| Address | Massachusetts General Hospital
Grb 1302
55 Fruit St
Boston MA 02114
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| Phone | 617/726-3447 |
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| Fax | 617/367-8936 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Faculty can login to make corrections and additions.
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Lu XM, Tompkins RG, Fischman AJ. Nitric oxide activates intradomain disulfide bond formation in the kinase loop of Akt1/PKBa after burn injury. Int J Mol Med. 2013 Mar; 31(3):740-50.
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Yo K, Yu YM, Zhao G, Bonab AA, Aikawa N, Tompkins RG, Fischman AJ. Brown adipose tissue and its modulation by a mitochondria-targeted peptide in rat burn injury-induced hypermetabolism. Am J Physiol Endocrinol Metab. 2013 Feb; 304(4):E331-41.
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Bandyopadhaya A, Kesarwani M, Que YA, He J, Padfield K, Tompkins R, Rahme LG. The Quorum Sensing Volatile Molecule 2-Amino Acetophenon Modulates Host Immune Responses in a Manner that Promotes Life with Unwanted Guests. PLoS Pathog. 2012 Nov; 8(11):e1003024.
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Carter EA, Winter D, Tolman C, Paul K, Hamrahi V, Tompkins RG, Fischman AJ. Combination of Radiation and Burn Injury Alters [18F] 2-Fluoro-2-Deoxy-D-Glucose Uptake in Mice. J Burn Care Res. 2012 Nov; 33(6):723-30.
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Palmieri TL, Nelson-Mooney K, Kagan RJ, Stubbs TK, Meyer WJ, Herndon DN, Hinson MI, Lee AF, Li NC, Kazis LE, Tompkins RG. Impact of hand burns on health-related quality of life in children younger than 5 years. J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S197-204.
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Sheridan RL, Lee AF, Kazis LE, Liang MH, Li NC, Hinson MI, Bauk H, Meyer WJ, Stubbs TK, Palmieri TL, Tompkins RG. The effect of family characteristics on the recovery of burn injuries in children. J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S205-12.
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Murphy JM, Kazis LE, Li NC, Lee AF, Hinson MI, White GW, Stoddard FJ, Palmieri TL, Meyer WJ, Liang MH, Tompkins RG. Test performance characteristics of a case-finding psychosocial questionnaire for children with burn injuries and their families. J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S221-8.
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Meyer WJ, Lee AF, Kazis LE, Li NC, Sheridan RL, Herndon DN, Hinson MI, Stubbs TK, Kagan RJ, Palmieri TL, Tompkins RG. Adolescent survivors of burn injuries and their parents' perceptions of recovery outcomes: do they agree or disagree? J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S213-20.
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Carter EA, Paul KW, Barrow SA, Fischman AJ, Tompkins RG. Previous burn injury predisposes mice to lipopolysaccharide-induced changes in glucose metabolism. J Burn Care Res. 2012 Sep-Oct; 33(5):683-9.
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Carey K, Kazis LE, Lee AF, Liang MH, Li NC, Hinson MI, Lydon MK, Bauk H, Shapiro GD, Tompkins RG. Measuring the cost of care for children with acute burn injury. J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S229-33.
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Warner P, Stubbs TK, Kagan RJ, Herndon DN, Palmieri TL, Kazis LE, Li NC, Lee AF, Meyer WJ, Tompkins RG. The effects of facial burns on health outcomes in children aged 5 to 18 years. J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S189-96.
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Tompkins RG, Liang MH, Lee AF, Kazis LE. The American Burn Association/Shriners Hospitals for Children Burn Outcomes Program: a progress report at 15 years. J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S173-8.
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Kazis LE, Lee AF, Hinson M, Liang MH, Rose MW, Palmieri TL, Meyer WJ, Kagan RJ, Li NC, Tompkins RG. Methods for assessment of health outcomes in children with burn injury: the Multi-Center Benchmarking Study. J Trauma Acute Care Surg. 2012 Sep; 73(3 Suppl 2):S179-88.
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Hamrahi V, Hamblin MR, Jung W, Benjamin JB, Paul KW, Fischman AJ, Tompkins RG, Carter EA. Gram-negative bacterial infection in thigh abscess can migrate to distant burn depending on burn depth. Interdiscip Perspect Infect Dis. 2012; 2012:567140.
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Weber JM, Sheridan RL, Fagan S, Ryan CM, Pasternack MS, Tompkins RG. Incidence of catheter-associated bloodstream infection after introduction of minocycline and rifampin antimicrobial-coated catheters in a pediatric burn population. J Burn Care Res. 2012 Jul; 33(4):539-43.
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Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, Warren HS, Cobb JP, Moldawer LL, Davis RW, Maier RV, Tompkins RG. Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg. 2012 May; 255(5):993-9.
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Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV. The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med. 2012 Apr; 40(4):1129-35.
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Xu H, Yu YM, Ma H, Carter EA, Fagan S, Tompkins RG, Fischman AJ. Glucose metabolism during the early "flow phase" after burn injury. J Surg Res. 2013 Jan; 179(1):e83-90.
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Hamrahi VF, Goverman J, Jung W, Wu JC, Fischman AJ, Tompkins RG, Yu YY, Fagan SP, Carter EA. In vivo molecular imaging of murine embryonic stem cells delivered to a burn wound surface via Integra® scaffolding. J Burn Care Res. 2012 Mar-Apr; 33(2):e49-54.
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Jeschke MG, Finnerty CC, Herndon DN, Song J, Boehning D, Tompkins RG, Baker HV, Gauglitz GG. Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response. Ann Surg. 2012 Feb; 255(2):370-8.
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Tompkins RG. Survival of children with burn injuries. Lancet. 2012 Mar 17; 379(9820):983-4.
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Song J, Finnerty CC, Herndon DN, Kraft R, Boehning D, Brooks NC, Tompkins RG, Jeschke MG. Thermal injury activates the eEF2K-dependent eEF2 pathway in pediatric patients. JPEN J Parenter Enteral Nutr. 2012 Sep; 36(5):596-602.
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Hipp J, Monaco J, Kunju LP, Cheng J, Yagi Y, Rodriguez-Canales J, Emmert-Buck MR, Hewitt S, Feldman MD, Tomaszewski JE, Toner M, Tompkins RG, Flotte T, Lucas D, Gilbertson JR, Madabhushi A, Balis U. Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification. Anal Cell Pathol (Amst). 2012; 35(4):251-65.
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Lu XM, Tompkins RG, Fischman AJ. SILAM for quantitative proteomics of liver Akt1/PKBa after burn injury. Int J Mol Med. 2012 Mar; 29(3):461-71.
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Lee HY, Kaneki M, Andreas J, Tompkins RG, Martyn JA. Novel mitochondria-targeted antioxidant peptide ameliorates burn-induced apoptosis and endoplasmic reticulum stress in the skeletal muscle of mice. Shock. 2011 Dec; 36(6):580-5.
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Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker HV, Finnerty CC, Jeschke MG, López MC, Klein MB, Gamelli RL, Gibran NS, Arnoldo B, Xu W, Zhang Y, Calvano SE, McDonald-Smith GP, Schoenfeld DA, Storey JD, Cobb JP, Warren HS, Moldawer LL, Herndon DN, Lowry SF, Maier RV, Davis RW, Tompkins RG. A genomic storm in critically injured humans. J Exp Med. 2011 Dec 19; 208(13):2581-90.
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Apidianakis Y, Que YA, Xu W, Tegos GP, Zimniak P, Hamblin MR, Tompkins RG, Xiao W, Rahme LG. Down-regulation of glutatione S-transferase a 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. FASEB J. 2012 Feb; 26(2):730-7.
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Warner EA, Kotz KT, Ungaro RF, Abouhamze AS, Lopez MC, Cuenca AG, Kelly-Scumpia KM, Moreno C, O'Malley KA, Lanz JD, Baker HV, Martin LC, Toner M, Tompkins RG, Efron PA, Moldawer LL. Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest. 2011 Dec; 91(12):1787-95.
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Carter EA, Bonab AA, Paul K, Yerxa J, Tompkins RG, Fischman AJ. Association of heat production with 18F-FDG accumulation in murine brown adipose tissue after stress. J Nucl Med. 2011 Oct; 52(10):1616-20.
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Desai KH, Tan CS, Leek JT, Maier RV, Tompkins RG, Storey JD. Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study. PLoS Med. 2011 Sep; 8(9):e1001093.
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Ryan CM, Antoon A, Fagan SP, Goverman J, Lawlor D, Sheridan RL, Tompkins RG. Considerations for preparedness for a pediatric burn disaster. J Burn Care Res. 2011 Sep-Oct; 32(5):e165-6.
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Stoddard FJ, White GW, Kazis LE, Murphy JM, Sorrentino EA, Hinson M, Kim Stubbs T, Chan G, Sheridan RL, Palmieri T, Kagan R, Herndon D, Tompkins RG. Patterns of medication administration from 2001 to 2009 in the treatment of children with acute burn injuries: a multicenter study. J Burn Care Res. 2011 Sep-Oct; 32(5):519-28.
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Yang W, Yamada M, Tamura Y, Chang K, Mao J, Zou L, Feng Y, Kida K, Scherrer-Crosbie M, Chao W, Ichinose F, Yu YM, Fischman AJ, Tompkins RG, Yao S, Kaneki M. Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance. J Pharmacol Exp Ther. 2011 Dec; 339(3):832-41.
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Carter EA, Bonab AA, Goverman J, Paul K, Yerxa J, Tompkins RG, Fischman AJ. Evaluation of the antioxidant peptide SS31 for treatment of burn-induced insulin resistance. Int J Mol Med. 2011 Oct; 28(4):589-94.
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Hipp J, Flotte T, Monaco J, Cheng J, Madabhushi A, Yagi Y, Rodriguez-Canales J, Emmert-Buck M, Dugan MC, Hewitt S, Toner M, Tompkins RG, Lucas D, Gilbertson JR, Balis UJ. Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess. J Pathol Inform. 2011; 2:25.
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Carter EA, Bonab AA, Hamrahi V, Pitman J, Winter D, Macintosh LJ, Cyr EM, Paul K, Yerxa J, Jung W, Tompkins RG, Fischman AJ. Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo. Life Sci. 2011 Jul 18; 89(3-4):78-85.
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Hipp JD, Cheng JY, Toner M, Tompkins RG, Balis UJ. Spatially Invariant Vector Quantization: A pattern matching algorithm for multiple classes of image subject matter including pathology. J Pathol Inform. 2011; 2:13.
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Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W. Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A. 2011 Mar 1; 108(9):3707-12.
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Shen CA, Fagan S, Fischman AJ, Carter EE, Chai JK, Lu XM, Yu YM, Tompkins RG. Effects of glucagon-like peptide 1 on glycemia control and its metabolic consequence after severe thermal injury--studies in an animal model. Surgery. 2011 May; 149(5):635-44.
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Rosenbach AE, Koria P, Goverman J, Kotz KT, Gupta A, Yu M, Fagan SP, Irimia D, Tompkins RG. Microfluidics for T- lymphocyte cell separation and inflammation monitoring in burn patients. Clin Transl Sci. 2011 Feb; 4(1):63-8.
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Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN. Early enteral nutrition in burns: compliance with guidelines and associated outcomes in a multicenter study. J Burn Care Res. 2011 Jan-Feb; 32(1):104-9.
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Beffa DC, Fischman AJ, Fagan SP, Hamrahi VF, Paul KW, Kaneki M, Yu YM, Tompkins RG, Carter EA. Simvastatin treatment improves survival in a murine model of burn sepsis: Role of interleukin 6. Burns. 2011 Mar; 37(2):222-6.
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Prelack K, Yu YM, Dylewski M, Lydon M, Sheridan RL, Tompkins RG. The contribution of muscle to whole-body protein turnover throughout the course of burn injury in children. J Burn Care Res. 2010 Nov-Dec; 31(6):942-8.
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Butler KL, Goverman J, Ma H, Fischman A, Yu YM, Bilodeau M, Rad AM, Bonab AA, Tompkins RG, Fagan SP. Stem cells and burns: review and therapeutic implications. J Burn Care Res. 2010 Nov-Dec; 31(6):874-81.
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Cuschieri J, Bulger E, Schaeffer V, Sakr S, Nathens AB, Hennessy L, Minei J, Moore EE, O'Keefe G, Sperry J, Remick D, Tompkins R, Maier RV. Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure. Shock. 2010 Oct; 34(4):346-51.
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Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD. Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics. J Proteome Res. 2010 Sep 3; 9(9):4779-89.
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Bonab AA, Carter EA, Paul K, Kaneki M, Yu YM, Tompkins RG, Fischman AJ. Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance. Int J Mol Med. 2010 Sep; 26(3):311-6.
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Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, Mindrinos MN, Smith RD, Davis RW, Tompkins RG, Toner M. Clinical microfluidics for neutrophil genomics and proteomics. Nat Med. 2010 Sep; 16(9):1042-7.
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Butler KL, Ambravaneswaran V, Agrawal N, Bilodeau M, Toner M, Tompkins RG, Fagan S, Irimia D. Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS One. 2010; 5(7):e11921.
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Yagi H, Soto-Gutierrez A, Navarro-Alvarez N, Nahmias Y, Goldwasser Y, Kitagawa Y, Tilles AW, Tompkins RG, Parekkadan B, Yarmush ML. Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1. Mol Ther. 2010 Oct; 18(10):1857-64.
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Yagi H, Soto-Gutierrez A, Kitagawa Y, Tilles AW, Tompkins RG, Yarmush ML. Bone marrow mesenchymal stromal cells attenuate organ injury induced by LPS and burn. Cell Transplant. 2010; 19(6):823-30.
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Yagi H, Soto-Gutierrez A, Parekkadan B, Kitagawa Y, Tompkins RG, Kobayashi N, Yarmush ML. Mesenchymal stem cells: Mechanisms of immunomodulation and homing. Cell Transplant. 2010; 19(6):667-79.
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Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G. Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22):9923-8.
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Stott SL, Lee RJ, Nagrath S, Yu M, Miyamoto DT, Ulkus L, Inserra EJ, Ulman M, Springer S, Nakamura Z, Moore AL, Tsukrov DI, Kempner ME, Dahl DM, Wu CL, Iafrate AJ, Smith MR, Tompkins RG, Sequist LV, Toner M, Haber DA, Maheswaran S. Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer. Sci Transl Med. 2010 Mar 31; 2(25):25ra23.
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Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN. Early acute kidney injury predicts progressive renal dysfunction and higher mortality in severely burned adults. J Burn Care Res. 2010 Jan-Feb; 31(1):83-92.
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Shinozaki S, Inoue Y, Yang W, Fukaya M, Carter EA, Yu YM, Ming-Yu Y, Fischman A, Tompkins R, Kaneki M. Farnesyltransferase inhibitor improved survival following endotoxin challenge in mice. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1459-64.
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Yagi H, Parekkadan B, Suganuma K, Soto-Gutierrez A, Tompkins RG, Tilles AW, Yarmush ML. Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure. Tissue Eng Part A. 2009 Nov; 15(11):3377-88.
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Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV. Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury. Ann Surg. 2009 Oct; 250(4):531-9.
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Lu XM, Hamrahi VF, Tompkins RG, Fischman AJ. Effect of insulin levels on the phosphorylation of specific amino acid residues in IRS-1: implications for burn-induced insulin resistance. Int J Mol Med. 2009 Oct; 24(4):531-8.
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Donovan AJ, Tompkins RK. Surgical research publication in a selection of research and surgical specialty journals. Surgery. 2010 Jan; 147(1):5-12.
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Stoddard FJ, Sorrentino EA, Ceranoglu TA, Saxe G, Murphy JM, Drake JE, Ronfeldt H, White GW, Kagan J, Snidman N, Sheridan RL, Tompkins RG. Preliminary evidence for the effects of morphine on posttraumatic stress disorder symptoms in one- to four-year-olds with burns. J Burn Care Res. 2009 Sep-Oct; 30(5):836-43.
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Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, Tompkins RG. Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. Int J Mol Med. 2009 Sep; 24(3):387-92.
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Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG. A genomic score prognostic of outcome in trauma patients. Mol Med. 2009 Jul-Aug; 15(7-8):220-7.
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Yin HN, Chai JK, Yu YM, Shen CA, Wu YQ, Yao YM, Liu H, Liang LM, Tompkins RG, Sheng ZY. Regulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated rats. J Trauma. 2009 Apr; 66(4):1083-90.
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Cheng X, Gupta A, Chen C, Tompkins RG, Rodriguez W, Toner M. Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics. Lab Chip. 2009 May 21; 9(10):1357-64.
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Qian WJ, Liu T, Petyuk VA, Gritsenko MA, Petritis BO, Polpitiya AD, Kaushal A, Xiao W, Finnerty CC, Jeschke MG, Jaitly N, Monroe ME, Moore RJ, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD. Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample. J Proteome Res. 2009 Jan; 8(1):290-9.
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Palmieri TL, Warner P, Mlcak RP, Sheridan R, Kagan RJ, Herndon DN, Tompkins R, Greenhalgh DG. Inhalation injury in children: a 10 year experience at Shriners Hospitals for Children. J Burn Care Res. 2009 Jan-Feb; 30(1):206-8.
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Neely AN, Gardner J, Durkee P, Warden GD, Greenhalgh DG, Gallagher JJ, Herndon DN, Tompkins RG, Kagan RJ. Are topical antimicrobials effective against bacteria that are highly resistant to systemic antibiotics? J Burn Care Res. 2009 Jan-Feb; 30(1):19-29.
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Irimia D, Mindrinos M, Russom A, Xiao W, Wilhelmy J, Wang S, Heath JD, Kurn N, Tompkins RG, Davis RW, Toner M. Genome-wide transcriptome analysis of 150 cell samples. Integr Biol (Camb). 2009 Jan; 1(1):99-107.
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Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Silver GM, Jeschke MG, Finnerty CC, Tompkins RG, Herndon DN. Impact of oxandrolone treatment on acute outcomes after severe burn injury. J Burn Care Res. 2008 Nov-Dec; 29(6):902-6.
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Huang R, Barber TA, Schmidt MA, Tompkins RG, Toner M, Bianchi DW, Kapur R, Flejter WL. A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women. Prenat Diagn. 2008 Oct; 28(10):892-9.
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Finnerty CC, Jeschke MG, Herndon DN, Gamelli R, Gibran N, Klein M, Silver G, Arnoldo B, Remick D, Tompkins RG. Temporal cytokine profiles in severely burned patients: a comparison of adults and children. Mol Med. 2008 Sep-Oct; 14(9-10):553-60.
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Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, Inserra E, Diederichs S, Iafrate AJ, Bell DW, Digumarthy S, Muzikansky A, Irimia D, Settleman J, Tompkins RG, Lynch TJ, Toner M, Haber DA. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med. 2008 Jul 24; 359(4):366-77.
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Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE. Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients. J Am Coll Surg. 2008 Oct; 207(4):459-67.
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Tzika AA, Astrakas LG, Cao H, Mintzopoulos D, Zhang Q, Padfield K, Yu H, Mindrinos MN, Rahme LG, Tompkins RG. Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma. Int J Mol Med. 2008 Jun; 21(6):825-32.
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Cabral CB, Bullock KH, Bischoff DJ, Tompkins RG, Yu YM, Kelleher JK. Estimating glutathione synthesis with deuterated water: a model for peptide biosynthesis. Anal Biochem. 2008 Aug 1; 379(1):40-4.
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Russom A, Sethu P, Irimia D, Mindrinos MN, Calvano SE, Garcia I, Finnerty C, Tannahill C, Abouhamze A, Wilhelmy J, López MC, Baker HV, Herndon DN, Lowry SF, Maier RV, Davis RW, Moldawer LL, Tompkins RG, Toner M. Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem. 2008 May; 54(5):891-900.
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Zhang Q, Ma B, Fischman AJ, Tompkins RG, Carter EA. Increased uncoupling protein 1 mRNA expression in mice brown adipose tissue after burn injury. J Burn Care Res. 2008 Mar-Apr; 29(2):358-62.
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Zhang Q, Carter EA, Ma B, Fischman AJ, Tompkins RG. Burn-related metabolic and signaling changes in rat brain. J Burn Care Res. 2008 Mar-Apr; 29(2):346-52.
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Di Carlo D, Edd JF, Irimia D, Tompkins RG, Toner M. Equilibrium separation and filtration of particles using differential inertial focusing. Anal Chem. 2008 Mar 15; 80(6):2204-11.
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Tzika AA, Mintzopoulos D, Padfield K, Wilhelmy J, Mindrinos MN, Yu H, Cao H, Zhang Q, Astrakas LG, Zhang J, Yu YM, Rahme LG, Tompkins RG. Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn. Int J Mol Med. 2008 Feb; 21(2):201-8.
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Toner M, Tompkins RG. Invention, innovation, entrepreneurship in academic medical centers. Surgery. 2008 Feb; 143(2):168-71.
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Apidianakis Y, Mindrinos MN, Xiao W, Tegos GP, Papisov MI, Hamblin MR, Davis RW, Tompkins RG, Rahme LG. Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma. PLoS One. 2007; 2(12):e1356.
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Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, Smith MR, Kwak EL, Digumarthy S, Muzikansky A, Ryan P, Balis UJ, Tompkins RG, Haber DA, Toner M. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature. 2007 Dec 20; 450(7173):1235-9.
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Di Carlo D, Irimia D, Tompkins RG, Toner M. Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):18892-7.
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Greenhalgh DG, Saffle JR, Holmes JH, Gamelli RL, Palmieri TL, Horton JW, Tompkins RG, Traber DL, Mozingo DW, Deitch EA, Goodwin CW, Herndon DN, Gallagher JJ, Sanford AP, Jeng JC, Ahrenholz DH, Neely AN, O'Mara MS, Wolf SE, Purdue GF, Garner WL, Yowler CJ, Latenser BA. American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res. 2007 Nov-Dec; 28(6):776-90.
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Murakami K, Enkhbaatar P, Yu YM, Traber LD, Cox RA, Hawkins HK, Tompkins RG, Herndon D, Traber DL. L-arginine attenuates acute lung injury after smoke inhalation and burn injury in sheep. Shock. 2007 Oct; 28(4):477-83.
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Lesic B, Lépine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S, Tzika AA, Tompkins RG, Rahme LG. Inhibitors of pathogen intercellular signals as selective anti-infective compounds. PLoS Pathog. 2007 Sep 14; 3(9):1229-39.
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Cheng X, Irimia D, Dixon M, Ziperstein JC, Demirci U, Zamir L, Tompkins RG, Toner M, Rodriguez WR. A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings. J Acquir Immune Defic Syndr. 2007 Jul 1; 45(3):257-61.
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Klein MB, Hayden D, Elson C, Nathens AB, Gamelli RL, Gibran NS, Herndon DN, Arnoldo B, Silver G, Schoenfeld D, Tompkins RG. The association between fluid administration and outcome following major burn: a multicenter study. Ann Surg. 2007 Apr; 245(4):622-8.
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Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV. The practice of venous thromboembolism prophylaxis in the major trauma patient. J Trauma. 2007 Mar; 62(3):557-62; discussion 562-3.
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Silver GM, Klein MB, Herndon DN, Gamelli RL, Gibran NS, Altstein L, McDonald-Smith GP, Tompkins RG, Hunt JL. Standard operating procedures for the clinical management of patients enrolled in a prospective study of Inflammation and the Host Response to Thermal Injury. J Burn Care Res. 2007 Mar-Apr; 28(2):222-30.
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Zhang Q, Cao H, Astrakas LG, Mintzopoulos D, Mindrinos MN, Schulz J, Tompkins RG, Rahme LG, Tzika AA. Uncoupling protein 3 expression and intramyocellular lipid accumulation by NMR following local burn trauma. Int J Mol Med. 2006 Dec; 18(6):1223-9.
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Cheng X, Irimia D, Dixon M, Sekine K, Demirci U, Zamir L, Tompkins RG, Rodriguez W, Toner M. A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects. Lab Chip. 2007 Feb; 7(2):170-8.
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Shinoda M, Tilles AW, Kobayashi N, Wakabayashi G, Takayanagi A, Totsugawa T, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Tanaka N, Kitajima M, Tompkins RG, Toner M, Yarmush ML. A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats. J Surg Res. 2007 Jan; 137(1):130-40.
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Laudanski K, Miller-Graziano C, Xiao W, Mindrinos MN, Richards DR, De A, Moldawer LL, Maier RV, Bankey P, Baker HV, Brownstein BH, Cobb JP, Calvano SE, Davis RW, Tompkins RG. Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways. Proc Natl Acad Sci U S A. 2006 Oct 17; 103(42):15564-9.
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Padfield KE, Zhang Q, Gopalan S, Tzika AA, Mindrinos MN, Tompkins RG, Rahme LG. Local and distant burn injury alter immuno-inflammatory gene expression in skeletal muscle. J Trauma. 2006 Aug; 61(2):280-92.
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Sethu P, Moldawer LL, Mindrinos MN, Scumpia PO, Tannahill CL, Wilhelmy J, Efron PA, Brownstein BH, Tompkins RG, Toner M. Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis. Anal Chem. 2006 Aug 1; 78(15):5453-61.
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Klein MB, Silver G, Gamelli RL, Gibran NS, Herndon DN, Hunt JL, Tompkins RG. Inflammation and the host response to injury: an overview of the multicenter study of the genomic and proteomic response to burn injury. J Burn Care Res. 2006 Jul-Aug; 27(4):448-51.
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Sekine K, Revzin A, Tompkins RG, Toner M. Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene) glycol-coated glass slides. J Immunol Methods. 2006 Jun 30; 313(1-2):96-109.
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Liu T, Qian WJ, Gritsenko MA, Xiao W, Moldawer LL, Kaushal A, Monroe ME, Varnum SM, Moore RJ, Purvine SO, Maier RV, Davis RW, Tompkins RG, Camp DG, Smith RD. High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics. 2006 Oct; 5(10):1899-913.
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Beffa DC, Carter EA, Lu XM, Yu YM, Prelack K, Sheridan RL, Young VR, Fischman AJ, Tompkins RG. Negative chemical ionization gas chromatography/mass spectrometry to quantify urinary 3-methylhistidine: application to burn injury. Anal Biochem. 2006 Aug 1; 355(1):95-101.
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Shinoda M, Tilles AW, Wakabayashi G, Takayanagi A, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Kitajima M, Tompkins RG, Toner M, Yarmush ML. Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist. Tissue Eng. 2006 May; 12(5):1313-23.
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Yasuhara S, Kaneki M, Sugita H, Sugita M, Asai A, Sahani N, Chon JY, Tompkins RG, Martyn JA. Adipocyte apoptosis after burn injury is associated with altered fat metabolism. J Burn Care Res. 2006 May-Jun; 27(3):367-76.
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Sugimachi K, Roach KL, Rhoads DB, Tompkins RG, Toner M. Nonmetabolizable glucose compounds impart cryotolerance to primary rat hepatocytes. Tissue Eng. 2006 Mar; 12(3):579-88.
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De AK, Miller-Graziano CL, Calvano SE, Laudanski K, Lowry SF, Moldawer LL, Remick DG, Rajicic N, Schoenfeld D, Tompkins RG. Selective activation of peripheral blood T cell subsets by endotoxin infusion in healthy human subjects corresponds to differential chemokine activation. J Immunol. 2005 Nov 1; 175(9):6155-62.
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Sin A, Murthy SK, Revzin A, Tompkins RG, Toner M. Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes. Biotechnol Bioeng. 2005 Sep 30; 91(7):816-26.
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Storey JD, Xiao W, Leek JT, Tompkins RG, Davis RW. Significance analysis of time course microarray experiments. Proc Natl Acad Sci U S A. 2005 Sep 6; 102(36):12837-42.
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Lu XM, Lu M, Tompkins RG, Fischman AJ. Site-specific detection of S-nitrosylated PKB alpha/Akt1 from rat soleus muscle using CapLC-Q-TOF(micro) mass spectrometry. J Mass Spectrom. 2005 Sep; 40(9):1140-8.
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Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, Tompkins RG, Rahme LG, Tzika AA. Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis. FASEB J. 2005 Sep; 19(11):1431-40.
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Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF. A network-based analysis of systemic inflammation in humans. Nature. 2005 Oct 13; 437(7061):1032-7.
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Zhang Q, Carter EA, Ma BY, White M, Fischman AJ, Tompkins RG. Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation. Life Sci. 2005 Oct 28; 77(24):3068-77.
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Lu XM, Lu MY, Fischman AJ, Tompkins RG. A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro). J Mass Spectrom. 2005 May; 40(5):599-607.
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Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA. Burn injury causes mitochondrial dysfunction in skeletal muscle. Proc Natl Acad Sci U S A. 2005 Apr 12; 102(15):5368-73.
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Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins RG, Baker HV, Bankey P, Billiar T, Brownstein BH, Calvano SE, Camp D, Chaudry I, Cobb JP, Davis RW, Elson CM, Freeman B, Gamelli R, Gibran N, Harbrecht B, Hayden DL, Heagy W, Heimbach D, Herndon DN, Horton J, Hunt J, Laudanski K, Lederer J, Lowry SF, Maier RV, Mannick J, McKinley B, Miller-Graziano C, Mindrinos MN, Minei J, Moldawer LL, Moore E, Moore F, Munford R, Nathens A, O'keefe G, Purdue G, Rahme L, Remick D, Sailors M, Schoenfeld DA, Shapiro M, Silver G, Smith R, Stephanopoulos G, Stormo G, Tompkins RG, Toner M, Warren S, West M, Wolfe S, Xiao W, Young V. Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A. 2005 Mar 29; 102(13):4801-6.
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Qian WJ, Monroe ME, Liu T, Jacobs JM, Anderson GA, Shen Y, Moore RJ, Anderson DJ, Zhang R, Calvano SE, Lowry SF, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Camp DG, Smith RD. Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics. 2005 May; 4(5):700-9.
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Yokoyama T, Banta S, Berthiaume F, Nagrath D, Tompkins RG, Yarmush ML. Evolution of intrahepatic carbon, nitrogen, and energy metabolism in a D-galactosamine-induced rat liver failure model. Metab Eng. 2005 Mar; 7(2):88-103.
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Qian WJ, Jacobs JM, Camp DG, Monroe ME, Moore RJ, Gritsenko MA, Calvano SE, Lowry SF, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Smith RD. Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry. Proteomics. 2005 Feb; 5(2):572-84.
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Sosef MN, Baust JM, Sugimachi K, Fowler A, Tompkins RG, Toner M. Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function. Ann Surg. 2005 Jan; 241(1):125-33.
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Murthy SK, Sin A, Tompkins RG, Toner M. Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers. Langmuir. 2004 Dec 21; 20(26):11649-55.
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Feezor RJ, Baker HV, Mindrinos M, Hayden D, Tannahill CL, Brownstein BH, Fay A, MacMillan S, Laramie J, Xiao W, Moldawer LL, Cobb JP, Laudanski K, Miller-Graziano CL, Maier RV, Schoenfeld D, Davis RW, Tompkins RG. Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genomics. 2004 Nov 17; 19(3):247-54.
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Sethu P, Anahtar M, Moldawer LL, Tompkins RG, Toner M. Continuous flow microfluidic device for rapid erythrocyte lysis. Anal Chem. 2004 Nov 1; 76(21):6247-53.
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Irimia D, Tompkins RG, Toner M. Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device. Anal Chem. 2004 Oct 15; 76(20):6137-43.
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Revzin A, Sekine K, Sin A, Tompkins RG, Toner M. Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes. Lab Chip. 2005 Jan; 5(1):30-7.
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Carter EA, Burks D, Fischman AJ, White M, Tompkins RG. Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue. Int J Mol Med. 2004 Oct; 14(4):653-8.
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Herndon DN, Tompkins RG. Support of the metabolic response to burn injury. Lancet. 2004 Jun 5; 363(9424):1895-902.
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Sheridan RL, Prelack K, Yu YM, Lydon M, Petras L, Young VR, Tompkins RG. Short-term enteral glutamine does not enhance protein accretion in burned children: a stable isotope study. Surgery. 2004 Jun; 135(6):671-8.
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Shen Y, Jacobs JM, Camp DG, Fang R, Moore RJ, Smith RD, Xiao W, Davis RW, Tompkins RG. Ultra-high-efficiency strong cation exchange LC/RPLC/MS/MS for high dynamic range characterization of the human plasma proteome. Anal Chem. 2004 Feb 15; 76(4):1134-44.
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Sheridan RL, Tompkins RG. What's new in burns and metabolism. J Am Coll Surg. 2004 Feb; 198(2):243-63.
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Mokuno Y, Berthiaume F, Tompkins RG, Balis UJ, Yarmush ML. Technique for expanding the donor liver pool: heat shock preconditioning in a rat fatty liver model. Liver Transpl. 2004 Feb; 10(2):264-72.
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Déziel E, Lépine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG. Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proc Natl Acad Sci U S A. 2004 Feb 3; 101(5):1339-44.
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Sugimachi K, Sosef MN, Baust JM, Fowler A, Tompkins RG, Toner M. Long-term function of cryopreserved rat hepatocytes in a coculture system. Cell Transplant. 2004; 13(2):187-95.
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Chen CL, Fei Z, Carter EA, Lu XM, Hu RH, Young VR, Tompkins RG, Yu YM. Metabolic fate of extrahepatic arginine in liver after burn injury. Metabolism. 2003 Oct; 52(10):1232-9.
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Pawlik TM, Carter EA, Bode BP, Fischman AJ, Tompkins RG. Central role of interleukin-6 in burn induced stimulation of hepatic amino acid transport. Int J Mol Med. 2003 Oct; 12(4):541-8.
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Tompkins RK. A giant with a gentle side. Surgery. 2003 Sep; 134(3):509-10.
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Duffy JP, Hines OJ, Liu JH, Ko CY, Cortina G, Isacoff WH, Nguyen H, Leonardi M, Tompkins RK, Reber HA. Improved survival for adenocarcinoma of the ampulla of Vater: fifty-five consecutive resections. Arch Surg. 2003 Sep; 138(9):941-8; discussion 948-50.
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Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG. The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa. Infect Immun. 2003 Jul; 71(7):4059-66.
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Shito M, Tilles AW, Tompkins RG, Yarmush ML, Toner M. Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure. J Surg Res. 2003 May 1; 111(1):53-62.
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Xu J, Fei Z, Yu YM, Xu W, Rhodes A, Tompkins RG, Schulz JT. In vivo rabbit hindquarter model for assessment of regional burn hypermetabolism. J Appl Physiol. 2003 Jan; 94(1):135-40.
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Ryan CM, Schoenfeld DA, Malloy M, Schulz JT, Sheridan RL, Tompkins RG. Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors. J Burn Care Rehabil. 2002 Sep-Oct; 23(5):311-7.
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Weber JM, Sheridan RL, Schulz JT, Tompkins RG, Ryan CM. Effectiveness of bacteria-controlled nursing units in preventing cross-colonization with resistant bacteria in severely burned children. Infect Control Hosp Epidemiol. 2002 Sep; 23(9):549-51.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler MW, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JL, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnston KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, MacFadyen BV, Tompkins RK. Scientific data from clinical trials: investigators' responsibilities and rights. World J Surg. 2002 Jun; 26(6):637-8.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler MW, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JL, Grosfeld JL, McFadden DW, Souby WW, Pruitt BA, Johnston KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, MacFadyen BV, Tompkins RK. Scientific data from clinical trials: investigators' responsibilities and rights. Arch Surg. 2002 Jun; 137(6):639-40.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler MW, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JL, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnston KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, MacFadyen BV, Tompkins RK. Scientific data from clinical trials: investigators' responsibilities and rights. Surg Laparosc Endosc Percutan Tech. 2002 Jun; 12(3):2 p preceding 145.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler MW, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JL, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnson KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, MacFadyen BV, Tompkins RK. Consensus statement on scientific data from clinical trials and investigators' responsibilities and rights. Am J Surg. 2002 Jun; 183(6):605-6.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler MW, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JL, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnston KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, MacFadyen BV, Tompkins RK. Scientific data from clinical trials: investigators' responsibilities and rights. J Vasc Surg. 2002 Jun; 35(6):1303-4.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler MW, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JI, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnston KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, Tompkins RK, MacFadyen BV. Scientific data from clinical trials: investigators' responsibilities and rights. Ann Surg Oncol. 2002 Jun; 9(5):421-2.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Büchler MW, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JL, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnston KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, McFadyen BV, Tompkins RK. Scientific data from clinical trials: investigators' responsibilities and rights. Br J Surg. 2002 Jun; 89(6):678-9.
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Polk HC, Bowden TA, Rikkers LF, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler M, Neoptolemos JP, Fazio VW, Schwartz SI, Cameron JL, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnston KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, MacFadyen BV, Tompkins RK. Scientific data from clinical trials: investigators' responsibilities and rights. Surg Endosc. 2002 Jun; 16(6):1019-20.
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Polk HC, Bowden TA, Rikkers L, Balch CM, Organ CH, Murie JA, Pories WJ, Buechler MW, Neoptolemos JP, Faxio VW, Schwartz SI, Cameron JL, Kelly KA, Grosfeld JL, McFadden DW, Souba WW, Pruitt BA, Johnson KW, Rutherford RB, Arregui ME, Scott-Conner CE, Warshaw AL, Sarr MG, Cuschieri A, MacFadyen BV, Tompkins RK. Scientific data from clinical trials: investigators' responsibilities and rights. J Gastrointest Surg. 2002 May-Jun; 6(3):512-3.
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Kazis LE, Liang MH, Lee A, Ren XS, Phillips CB, Hinson M, Calvert C, Cullen M, Daugherty MB, Goodwin CW, Jenkins M, McCauley RL, Meyer WJ, Palmieri T, Pidcock F, Reilly D, Warden G, Wood D, Tompkins R. The development, validation, and testing of a health outcomes burn questionnaire for infants and children 5 years of age and younger: American Burn Association/Shriners Hospitals for Children. J Burn Care Rehabil. 2002 May-Jun; 23(3):196-207.
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Fischman AJ, Hsu H, Carter EA, Yu YM, Tompkins RG, Guerrero JL, Young VR, Alpert NM. Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H2(15)O. J Appl Physiol. 2002 Apr; 92(4):1709-16.
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Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ. Mapping of local renal blood flow with PET and H(2)(15)O. J Nucl Med. 2002 Apr; 43(4):470-5.
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Yu YM, Ryan CM, Fei ZW, Lu XM, Castillo L, Schultz JT, Tompkins RG, Young VR. Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans. Am J Physiol Endocrinol Metab. 2002 Feb; 282(2):E247-58.
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Sugita H, Kaneki M, Tokunaga E, Sugita M, Koike C, Yasuhara S, Tompkins RG, Martyn JA. Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance. Am J Physiol Endocrinol Metab. 2002 Feb; 282(2):E386-94.
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Tilles AW, Berthiaume F, Yarmush ML, Tompkins RG, Toner M. Bioengineering of liver assist devices. J Hepatobiliary Pancreat Surg. 2002; 9(6):686-96.
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Sheridan RL, Schulz JT, Ryan CM, Schnitzer JJ, Lawlor D, Driscoll DN, Donelan MB, Tompkins RG. Long-term consequences of toxic epidermal necrolysis in children. Pediatrics. 2002 Jan; 109(1):74-8.
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Washizu J, Berthiaume F, Mokuno Y, Tompkins RG, Toner M, Yarmush ML. Long-term maintenance of cytochrome P450 activities by rat hepatocyte/3T3 cell co-cultures in heparinized human plasma. Tissue Eng. 2001 Dec; 7(6):691-703.
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Tompkins RK, Ko CY, Donovan AJ. Internationalization of general surgical journals: origin and content of articles published in North America and Great Britain from 1983 to 1998. Arch Surg. 2001 Dec; 136(12):1345-51; discussion 1351-2.
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Cao H, Krishnan G, Goumnerov B, Tsongalis J, Tompkins R, Rahme LG. A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism. Proc Natl Acad Sci U S A. 2001 Dec 4; 98(25):14613-8.
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Sheridan RL, Weber JM, Pasternack MS, Tompkins RG. Antibiotic prophylaxis for group A streptococcal burn wound infection is not necessary. J Trauma. 2001 Aug; 51(2):352-5.
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Arai K, Lee K, Berthiaume F, Tompkins RG, Yarmush ML. Intrahepatic amino acid and glucose metabolism in a D-galactosamine-induced rat liver failure model. Hepatology. 2001 Aug; 34(2):360-71.
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Sheridan RL, Morgan JR, Cusick JL, Petras LM, Lydon MM, Tompkins RG. Initial experience with a composite autologous skin substitute. Burns. 2001 Aug; 27(5):421-4.
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Shito M, Balis UJ, Tompkins RG, Yarmush ML, Toner M. A fulminant hepatic failure model in the rat: involvement of interleukin-1beta and tumor necrosis factor-alpha. Dig Dis Sci. 2001 Aug; 46(8):1700-8.
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Shito M, Kim NH, Baskaran H, Tilles AW, Tompkins RG, Yarmush ML, Toner M. In vitro and in vivo evaluation of albumin synthesis rate of porcine hepatocytes in a flat-plate bioreactor. Artif Organs. 2001 Jul; 25(7):571-8.
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Yu YM, Ryan CM, Castillo L, Lu XM, Beaumier L, Tompkins RG, Young VR. Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal. Am J Physiol Endocrinol Metab. 2001 Mar; 280(3):E509-17.
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Sheridan RL, Schulz JT, Weber JM, Ryan CM, Pasternack MS, Tompkins RG. Cutaneous herpetic infections complicating burns. Burns. 2000 Nov; 26(7):621-4.
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Washizu J, Chan C, Berthiaume F, Tompkins RG, Toner M, Yarmush ML. Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma. Tissue Eng. 2000 Oct; 6(5):497-504.
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Washizu J, Berthiaume F, Chan C, Tompkins RG, Toner M, Yarmush ML. Optimization of rat hepatocyte culture in citrated human plasma. J Surg Res. 2000 Oct; 93(2):237-46.
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Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG. Plants and animals share functionally common bacterial virulence factors. Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16):8815-21.
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Whang EE, Danial T, Dunn JC, Ashley SW, Reber HA, Lewin TJ, Tompkins RK. The spectrum of mucin-producing adenocarcinoma of the pancreas. Pancreas. 2000 Aug; 21(2):147-51.
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Lyons J, Rauh-Pfeiffer A, Yu YM, Lu XM, Zurakowski D, Tompkins RG, Ajami AM, Young VR, Castillo L. Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet. Proc Natl Acad Sci U S A. 2000 May 9; 97(10):5071-6.
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Schulz JT, Sheridan RL, Ryan CM, MacKool B, Tompkins RG. A 10-year experience with toxic epidermal necrolysis. J Burn Care Rehabil. 2000 May-Jun; 21(3):199-204.
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Sheridan RL, Remensnyder JP, Schnitzer JJ, Schulz JT, Ryan CM, Tompkins RG. Current expectations for survival in pediatric burns. Arch Pediatr Adolesc Med. 2000 Mar; 154(3):245-9.
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Sheridan RL, Hinson MI, Liang MH, Nackel AF, Schoenfeld DA, Ryan CM, Mulligan JL, Tompkins RG. Long-term outcome of children surviving massive burns. JAMA. 2000 Jan 5; 283(1):69-73.
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Daltroy LH, Liang MH, Phillips CB, Daugherty MB, Hinson M, Jenkins M, McCauley R, Meyer W, Munster A, Pidcock F, Reilly D, Tunell W, Warden G, Wood D, Tompkins R, Cullen M, Calvert C, Hunt J, Purdue G, Saffle J, Yurt R. American Burn Association/Shriners Hospitals for Children burn outcomes questionnaire: construction and psychometric properties. J Burn Care Rehabil. 2000 Jan-Feb; 21(1 Pt 1):29-39.
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Schulz JT, Tompkins RG, Burke JF. Artificial skin. Annu Rev Med. 2000; 51:231-44.
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Sheridan RL, Zapol WM, Ritz RH, Tompkins RG. Low-dose inhaled nitric oxide in acutely burned children with profound respiratory failure. Surgery. 1999 Nov; 126(5):856-62.
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Sheridan RL, Weber JM, Schulz JT, Ryan CM, Low HM, Tompkins RG. Management of severe toxic epidermal necrolysis in children. J Burn Care Rehabil. 1999 Nov-Dec; 20(6):497-500.
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Sheridan R, Weber J, Prelack K, Petras L, Lydon M, Tompkins R. Early burn center transfer shortens the length of hospitalization and reduces complications in children with serious burn injuries. J Burn Care Rehabil. 1999 Sep-Oct; 20(5):347-50.
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Ikezu T, Yasuhara S, Granneman JG, Kraemer FB, Okamoto T, Tompkins RG, Martyn JA. A unique mechanism of desensitization to lipolysis mediated by beta(3)-adrenoceptor in rats with thermal injury. Am J Physiol. 1999 Aug; 277(2 Pt 1):E316-24.
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Carter EA, Yu YM, Alpert NM, Bonab AA, Tompkins RG, Fischman AJ. Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine: effects of transamination and transmethylation. J Trauma. 1999 Aug; 47(2):341-5.
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Yarmush DM, MacDonald AD, Foy BD, Berthiaume F, Tompkins RG, Yarmush ML. Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver. J Burn Care Rehabil. 1999 Jul-Aug; 20(4):292-302.
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Sheridan RL, Weber JM, Pasternak MM, Mulligan JM, Tompkins RG. A 15-year experience with varicella infections in a pediatric burn unit. Burns. 1999 Jun; 25(4):353-6.
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Yu YM, Tompkins RG, Ryan CM, Young VR. The metabolic basis of the increase of the increase in energy expenditure in severely burned patients. JPEN J Parenter Enteral Nutr. 1999 May-Jun; 23(3):160-8.
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Sheridan RL, Baryza MJ, Pessina MA, O'Neill KM, Cipullo HM, Donelan MB, Ryan CM, Schulz JT, Schnitzer JJ, Tompkins RG. Acute hand burns in children: management and long-term outcome based on a 10-year experience with 698 injured hands. Ann Surg. 1999 Apr; 229(4):558-64.
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Sheridan R, Schulz J, Ryan C, Ackroyd F, Basha G, Tompkins R. Percutaneous endoscopic gastrostomy in burn patients. Surg Endosc. 1999 Apr; 13(4):401-2.
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Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM. Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc Natl Acad Sci U S A. 1999 Mar 2; 96(5):2408-13.
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Sheridan RL, Tompkins RG. Skin substitutes in burns. Burns. 1999 Mar; 25(2):97-103.
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Berthiaume F, Tompkins RG, Yarmush ML. Isolation and long-term maintenance of adult rat hepatocytes in culture. Methods Mol Med. 1999; 18:447-56.
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Sheridan RL, Lydon MM, Petras LM, Schomacker KT, Tompkins RG, Glatter RD, Parrish JA. Laser ablation of burns: initial clinical trial. Surgery. 1999 Jan; 125(1):92-5.
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Peirce EC, Dabbs CH, Rogers WK, Rawson FL, Tompkins R. A practical method of differential hypothermia to permit use of a low pump oxygenator flow. ASAIO J. 1998 Nov-Dec; 44(6):763-9.
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Medalie DA, Tompkins RG, Morgan JR. Characterization of a composite tissue model that supports clonal growth of human melanocytes in vitro and in vivo. J Invest Dermatol. 1998 Nov; 111(5):810-6.
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Sheridan R, Choucair R, Donelan M, Lydon M, Petras L, Tompkins R. Acellular allodermis in burns surgery: 1-year results of a pilot trial. J Burn Care Rehabil. 1998 Nov-Dec; 19(6):528-30.
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Fischman AJ, Yu YM, Livni E, Babich JW, Young VR, Alpert NM, Tompkins RG. Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans. Proc Natl Acad Sci U S A. 1998 Oct 27; 95(22):12793-8.
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Sheridan RL, Yu YM, Prelack K, Young VR, Burke JF, Tompkins RG. Maximal parenteral glucose oxidation in hypermetabolic young children: a stable isotope study. JPEN J Parenter Enteral Nutr. 1998 Jul-Aug; 22(4):212-6.
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Takabayashi T, Vannier E, Burke JF, Tompkins RG, Gelfand JA, Clark BD. Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells. J Infect Dis. 1998 Jun; 177(6):1622-8.
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Sheridan RL, Ryan CM, Yin LM, Hurley J, Tompkins RG. Death in the burn unit: sterile multiple organ failure. Burns. 1998 Jun; 24(4):307-11.
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Hu RH, Yu YM, Costa D, Young VR, Ryan CM, Burke JF, Tompkins RG. A rabbit model for metabolic studies after burn injury. J Surg Res. 1998 Mar; 75(2):153-60.
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Eming SA, Medalie DA, Tompkins RG, Yarmush ML, Morgan JR. Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft. Hum Gene Ther. 1998 Mar 1; 9(4):529-39.
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Ryan CM, Schoenfeld DA, Thorpe WP, Sheridan RL, Cassem EH, Tompkins RG. Objective estimates of the probability of death from burn injuries. N Engl J Med. 1998 Feb 5; 338(6):362-6.
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Rahme LG, Tan MW, Le L, Wong SM, Tompkins RG, Calderwood SB, Ausubel FM. Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):13245-50.
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Ikezu T, Okamoto T, Yonezawa K, Tompkins RG, Martyn JA. Analysis of thermal injury-induced insulin resistance in rodents. Implication of postreceptor mechanisms. J Biol Chem. 1997 Oct 3; 272(40):25289-95.
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Sheridan RL, Ryan CM, Petras LM, Lydon MK, Weber JM, Tompkins RG. Burns in children younger than two years of age: an experience with 200 consecutive admissions. Pediatrics. 1997 Oct; 100(4):721-3.
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Ryan CM, Thorpe W, Mullin P, Roberts W, Tompkins D, Kelleher P, Sheridan R, Tompkins R. A persistent fire hazard for older adults: cooking-related clothing ignition. J Am Geriatr Soc. 1997 Oct; 45(10):1283-5.
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Sheridan RL, Hinson M, Nackel A, Blaquiere M, Daley W, Querzoli B, Spezzafaro J, Lybarger P, Martyn J, Szyfelbein S, Tompkins R. Development of a pediatric burn pain and anxiety management program. J Burn Care Rehabil. 1997 Sep-Oct; 18(5):455-9; discussion 453-4.
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Medalie DA, Eming SA, Collins ME, Tompkins RG, Yarmush ML, Morgan JR. Differences in dermal analogs influence subsequent pigmentation, epidermal differentiation, basement membrane, and rete ridge formation of transplanted composite skin grafts. Transplantation. 1997 Aug 15; 64(3):454-65.
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Babich JW, Tompkins RG, Graham W, Barrow SA, Fischman AJ. Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism. J Nucl Med. 1997 Aug; 38(8):1316-22.
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Bischof JC, Ryan CM, Tompkins RG, Yarmush ML, Toner M. Ice formation in isolated human hepatocytes and human liver tissue. ASAIO J. 1997 Jul-Aug; 43(4):271-8.
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Sheridan RL, MacMillan K, Donelan M, Choucair R, Grevelink J, Petras L, Lydon M, Tompkins R. Tunable dye laser neovessel ablation as an adjunct to the management of hypertrophic scarring in burned children: pilot trial to establish safety. J Burn Care Rehabil. 1997 Jul-Aug; 18(4):317-20.
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Vogt JA, Yarmush DM, Yu YM, Zupke C, Fischman AJ, Tompkins RG, Burke JF. TCA cycle flux estimates from NMR- and GC-MS-determined [13C]glutamate isotopomers in liver. Am J Physiol. 1997 Jun; 272(6 Pt 1):C2049-62.
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Weber JM, Sheridan RL, Pasternack MS, Tompkins RG. Nosocomial infections in pediatric patients with burns. Am J Infect Control. 1997 Jun; 25(3):195-201.
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Zupke C, Tompkins R, Yarmush D, Yarmush M. Numerical isotopomer analysis: estimation of metabolic activity. Anal Biochem. 1997 May 1; 247(2):287-93.
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Prelack K, Dwyer J, Yu YM, Sheridan RL, Tompkins RG. Urinary urea nitrogen is imprecise as a predictor of protein balance in burned children. J Am Diet Assoc. 1997 May; 97(5):489-95.
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Sheridan RL, Hurford WE, Kacmarek RM, Ritz RH, Yin LM, Ryan CM, Tompkins RG. Inhaled nitric oxide in burn patients with respiratory failure. J Trauma. 1997 Apr; 42(4):629-34.
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Yamaguchi Y, Yu YM, Zupke C, Yarmush DM, Berthiaume F, Tompkins RG, Yarmush ML. Effect of burn injury on glucose and nitrogen metabolism in the liver: preliminary studies in a perfused liver system. Surgery. 1997 Mar; 121(3):295-303.
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Prelack K, Cunningham JJ, Sheridan RL, Tompkins RG. Energy and protein provisions for thermally injured children revisited: an outcome-based approach for determining requirements. J Burn Care Rehabil. 1997 Mar-Apr; 18(2):177-81; discussion 176.
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Tompkins RG. The role of proinflammatory cytokines in inflammatory and metabolic responses. Ann Surg. 1997 Mar; 225(3):243-5.
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Carter EA, Tompkins RG, Hsu H, Christian B, Alpert NM, Weise S, Fischman AJ. Metabolic alterations in muscle of thermally injured rabbits, measured by positron emission tomography. Life Sci. 1997; 61(1):39-44.
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Reiken SR, Wolfort SF, Berthiaume F, Compton C, Tompkins RG, Yarmush ML. Control of hypertrophic scar growth using selective photothermolysis. Lasers Surg Med. 1997; 21(1):7-12.
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Aiura K, Clark BD, Dinarello CA, Margolis NH, Kaplanski G, Burke JF, Tompkins RG, Gelfand JA. Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells. J Infect Dis. 1997 Jan; 175(1):123-9.
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Yu YM, Burke JF, Tompkins RG, Martin R, Young VR. Quantitative aspects of interorgan relationships among arginine and citrulline metabolism. Am J Physiol. 1996 Dec; 271(6 Pt 1):E1098-109.
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Stefanovich P, Matthew HW, Toner M, Tompkins RG, Yarmush ML. Extracorporeal plasma perfusion of cultured hepatocytes: effect of intermittent perfusion on hepatocyte function and morphology. J Surg Res. 1996 Nov; 66(1):57-63.
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Medalie DA, Tompkins RG, Morgan JR. Evaluation of acellular human dermis as a dermal analog in a composite skin graft. ASAIO J. 1996 Sep-Oct; 42(5):M455-62.
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Carter EA, Tompkins RG, Babich JW, Correia J, Bailey EM, Fischman AJ. Thermal injury in rats alters glucose utilization by skin, wound, and small intestine, but not by skeletal muscle. Metabolism. 1996 Sep; 45(9):1161-7.
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Matthew HW, Sternberg J, Stefanovich P, Morgan JR, Toner M, Tompkins RG, Yarmush ML. Effects of plasma exposure on cultured hepatocytes: Implications for bioartificial liver support. Biotechnol Bioeng. 1996 Jul 5; 51(1):100-11.
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Yu YM, Sheridan RL, Burke JF, Chapman TE, Tompkins RG, Young VR. Kinetics of plasma arginine and leucine in pediatric burn patients. Am J Clin Nutr. 1996 Jul; 64(1):60-6.
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Medalie DA, Eming SA, Tompkins RG, Yarmush ML, Krueger GG, Morgan JR. Evaluation of human skin reconstituted from composite grafts of cultured keratinocytes and human acellular dermis transplanted to athymic mice. J Invest Dermatol. 1996 Jul; 107(1):121-7.
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Carter EA, Tompkins RG, Babich JW, Correia JA, Fischman AJ. Decreased cerebral glucose utilization in rats during the ebb phase of thermal injury. J Trauma. 1996 Jun; 40(6):930-5.
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Wolfort SF, Reiken SR, Berthiaume F, Tompkins RG, Yarmush ML. Control of hypertrophic scar growth using antibody-targeted photolysis. J Surg Res. 1996 Apr; 62(1):17-22.
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Hsu H, Yu YM, Babich JW, Burke JF, Livni E, Tompkins RG, Young VR, Alpert NM, Fischman AJ. Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine. Proc Natl Acad Sci U S A. 1996 Mar 5; 93(5):1841-6.
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Moghe PV, Berthiaume F, Ezzell RM, Toner M, Tompkins RG, Yarmush ML. Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function. Biomaterials. 1996 Feb; 17(3):373-85.
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Sheridan RL, Briggs SE, Remensnyder JP, Tompkins RG. Management strategy in purpura fulminans with multiple organ failure in children. Burns. 1996 Feb; 22(1):53-6.
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Sheridan RL, Tompkins RG. Recent clinical experience with cultured autologous epithelium. Br J Plast Surg. 1996 Jan; 49(1):72-4.
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Eming SA, Lee J, Snow RG, Tompkins RG, Yarmush ML, Morgan JR. Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice--implications for the use of genetically modified keratinocytes to modulate dermal regeneration. J Invest Dermatol. 1995 Dec; 105(6):756-63.
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Yu YM, Ryan CM, Burke JF, Tompkins RG, Young VR. Relations among arginine, citrulline, ornithine, and leucine kinetics in adult burn patients. Am J Clin Nutr. 1995 Nov; 62(5):960-8.
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Sheridan RL, Schomaker KT, Lucchina LC, Hurley J, Yin LM, Tompkins RG, Jerath M, Torri A, Greaves KW, Bua DP. Burn depth estimation by use of indocyanine green fluorescence: initial human trial. J Burn Care Rehabil. 1995 Nov-Dec; 16(6):602-4.
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Morgan JR, LeDoux JM, Snow RG, Tompkins RG, Yarmush ML. Retrovirus infection: effect of time and target cell number. J Virol. 1995 Nov; 69(11):6994-7000.
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Sheridan RL, Kacmarek RM, McEttrick MM, Weber JM, Ryan CM, Doody DP, Ryan DP, Schnitzer JJ, Tompkins RG. Permissive hypercapnia as a ventilatory strategy in burned children: effect on barotrauma, pneumonia, and mortality. J Trauma. 1995 Nov; 39(5):854-9.
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Ryan CM, Atkins MB, Mier JW, Gelfand JA, Tompkins RG. Effects of malignancy and interleukin-2 infusion on gut macromolecular permeability. Crit Care Med. 1995 Nov; 23(11):1801-6.
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Sheridan RL, Petras L, Basha G, Salvo P, Cifrino C, Hinson M, McCabe M, Fallon J, Tompkins RG. Planimetry study of the percent of body surface represented by the hand and palm: sizing irregular burns is more accurately done with the palm. J Burn Care Rehabil. 1995 Nov-Dec; 16(6):605-6.
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Sheridan RL, Behringer GE, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF. Effective postoperative protection for grafted posterior surfaces: the quilted dressing. J Burn Care Rehabil. 1995 Nov-Dec; 16(6):607-9.
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Ryan CM, Sheridan RL, Schoenfeld DA, Warshaw AL, Tompkins RG. Postburn pancreatitis. Ann Surg. 1995 Aug; 222(2):163-70.
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Stefanovich P, Ezzell RM, Sheehan SJ, Tompkins RG, Yarmush ML, Toner M. Effects of hypothermia on the function, membrane integrity, and cytoskeletal structure of hepatocytes. Cryobiology. 1995 Aug; 32(4):389-403.
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Sheridan RL, Weber JM, Budkevich LG, Tompkins RG. Candidemia in the pediatric patient with burns. J Burn Care Rehabil. 1995 Jul-Aug; 16(4):440-3.
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Hansbrough JF, Herndon DN, Heimbach DM, Solem LD, Gamelli RL, Tompkins RG. Accelerated healing and reduced need for grafting in pediatric patients with burns treated with arginine-glycine-aspartic acid peptide matrix. RGD Study Group. J Burn Care Rehabil. 1995 Jul-Aug; 16(4):377-87.
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Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM. Common virulence factors for bacterial pathogenicity in plants and animals. Science. 1995 Jun 30; 268(5219):1899-902.
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Bischof JC, Padanilam J, Holmes WH, Ezzell RM, Lee RC, Tompkins RG, Yarmush ML, Toner M. Dynamics of cell membrane permeability changes at supraphysiological temperatures. Biophys J. 1995 Jun; 68(6):2608-14.
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Thorpe WP, Toner M, Ezzell RM, Tompkins RG, Yarmush ML. Dynamics of photoinduced cell plasma membrane injury. Biophys J. 1995 May; 68(5):2198-206.
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Sheridan RL, Stewart B, Tompkins RG. Solid organ procurement from burn patients. J Trauma. 1995 May; 38(5):824-5.
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Yu YM, Young VR, Tompkins RG, Burke JF. Comparative evaluation of the quantitative utilization of parenterally and enterally administered leucine and L-[1-13C,15N]leucine within the whole body and the splanchnic region. JPEN J Parenter Enteral Nutr. 1995 May-Jun; 19(3):209-15.
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Yu YM, Young VR, Castillo L, Chapman TE, Tompkins RG, Ryan CM, Burke JF. Plasma arginine and leucine kinetics and urea production rates in burn patients. Metabolism. 1995 May; 44(5):659-66.
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Rotem A, Matthew HW, Hsiao PH, Toner M, Tompkins RG, Yarmush ML. The activity of cytochrome P450IA1 in stable cultured rat hepatocytes. Toxicol In Vitro. 1995 Apr; 9(2):139-49.
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Sheridan RL, Hurley J, Smith MA, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF. The acutely burned hand: management and outcome based on a ten-year experience with 1047 acute hand burns. J Trauma. 1995 Mar; 38(3):406-11.
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Sheridan RL, Petras L, Basha G, Tompkins RG. Clinical experience with the use of biodegradable tacks in pediatric patients with burns. J Burn Care Rehabil. 1995 Mar-Apr; 16(2 Pt 1):143-4.
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Sheridan RL, Weber JM, Peterson HF, Tompkins RG. Central venous catheter sepsis with weekly catheter change in paediatric burn patients: an analysis of 221 catheters. Burns. 1995 Mar; 21(2):127-9.
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Sheridan RL, Ryan CM, Lee MJ, Mueller PR, Tompkins RG. Percutaneous cholecystostomy in the critically ill burn patient. J Trauma. 1995 Feb; 38(2):248-51.
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Sheridan RL, Ryan CM, Quinby WC, Blair J, Tompkins RG, Burke JF. Emergency management of major hydrofluoric acid exposures. Burns. 1995 Feb; 21(1):62-4.
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Fischman AJ, Babich JW, Barrow SA, Graham W, Carter E, Tompkins RG, Rubin RH. Detection of acute bacterial infection within soft tissue injuries using a 99mTc-labeled chemotactic peptide. J Trauma. 1995 Feb; 38(2):223-7.
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Sheridan RL, Tompkins RG. Cultured autologous epithelium in patients with burns of ninety percent or more of the body surface. J Trauma. 1995 Jan; 38(1):48-50.
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Sheridan RL, Prelack KM, Petras LM, Szyfelbein SK, Tompkins RG. Intraoperative reflectance oximetry in burn patients. J Clin Monit. 1995 Jan; 11(1):32-4.
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Sheridan RL, Briggs SE, Remensnyder JP, Gagnon SW, Doody DP, Ryan DP, Tompkins RG. The burn unit as a resource for the management of acute nonburn conditions in children. J Burn Care Rehabil. 1995 Jan-Feb; 16(1):62-4.
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Souba WW, Gamelli RL, Lorber MI, Thompson JS, Kron IL, Tompkins RG, Hoyt DB. Strategies for success in academic surgery. Surgery. 1995 Jan; 117(1):90-5.
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Bacha EA, Sheridan RL, Donohue GA, Tompkins RG. Staphylococcal toxic shock syndrome in a paediatric burn unit. Burns. 1994 Dec; 20(6):499-502.
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Sheridan RL, Weber J, Benjamin J, Pasternack MS, Tompkins RG. Control of methicillin-resistant Staphylococcus aureus in a pediatric burn unit. Am J Infect Control. 1994 Dec; 22(6):340-5.
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Bhatia SN, Toner M, Tompkins RG, Yarmush ML. Selective adhesion of hepatocytes on patterned surfaces. Ann N Y Acad Sci. 1994 Nov 30; 745:187-209.
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Carter EA, Derojas-Walker T, Tamir S, Tannenbaum SR, Yu YM, Tompkins RG. Nitric oxide production is intensely and persistently increased in tissue by thermal injury. Biochem J. 1994 Nov 15; 304 ( Pt 1):201-4.
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Foy BD, Rotem A, Toner M, Tompkins RG, Yarmush ML. A device to measure the oxygen uptake rate of attached cells: importance in bioartificial organ design. Cell Transplant. 1994 Nov-Dec; 3(6):515-27.
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Sheridan RL, McEttrick M, Bacha G, Stoddard F, Tompkins RG. Midazolam infusion in pediatric patients with burns who are undergoing mechanical ventilation. J Burn Care Rehabil. 1994 Nov-Dec; 15(6):515-8.
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Herman LW, Fischman AJ, Tompkins RG, Hanson RN, Byon C, Strauss HW, Elmaleh DR. The use of pentafluorophenyl derivatives for the 18F labelling of proteins. Nucl Med Biol. 1994 Oct; 21(7):1005-10.
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Sheridan RL, Weber JM, Tompkins RG. Femoral arterial catheterization in paediatric burn patients. Burns. 1994 Oct; 20(5):451-2.
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Sheridan RL, Hurley J, Lynch L, Balmer J, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF. Modified Stryker frame for intraoperative positioning of the patient with burns. J Burn Care Rehabil. 1994 Sep-Oct; 15(5):438-40.
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Morgan JR, Lee J, Tompkins RG, Yarmush ML. Rapid quantitation of recombinant retroviruses. Biotechnol Prog. 1994 Jul-Aug; 10(4):441-6.
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Berthiaume F, Reiken SR, Toner M, Tompkins RG, Yarmush ML. Antibody-targeted photolysis of bacteria in vivo. Biotechnology (N Y). 1994 Jul; 12(7):703-6.
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Vogt JA, Fischman AJ, Kempf M, Yu YM, Tompkins RG, Burke JF. A general model for analysis of the tricarboxylic acid cycle with use of [13C]glutamate isotopomer measurements. Am J Physiol. 1994 Jun; 266(6 Pt 1):E1012-22.
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Sheridan RL, Tompkins RG. Prognostic significance of prehospital cardiac or pulmonary resuscitation in paediatric burns patients. Burns. 1994 Jun; 20(3):265-6.
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Padanilam JT, Bischof JC, Lee RC, Cravalho EG, Tompkins RG, Yarmush ML, Toner M. Effectiveness of poloxamer 188 in arresting calcein leakage from thermally damaged isolated skeletal muscle cells. Ann N Y Acad Sci. 1994 May 31; 720:111-23.
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Borel Rinkes IH, Toner M, Tompkins RG, Yarmush ML. An extracorporeal microscopy perfusion chamber for on-line studies of environmental effects on cultured hepatocytes. J Biomech Eng. 1994 May; 116(2):135-9.
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Meng J, Elmaleh DR, Jyawook S, Weiss S, Alpert NM, Babich JW, Tompkins RG, Fischman AJ. Synthesis of 2-[18F]fluoro-2-deoxy-L-glucose and positron emission tomography studies in monkeys. Nucl Med Biol. 1994 May; 21(4):633-40.
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Mester M, Carter EA, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD. Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. Surgery. 1994 May; 115(5):588-96.
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Trop M, Carter EA, Schiffrin EJ, Tompkins RG. Arterial blood pressure immediately after thermal injury: the role of anesthesia. J Burn Care Rehabil. 1994 May-Jun; 15(3):224-31.
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Stevens EJ, Ryan CM, Friedberg JS, Barnhill RL, Yarmush ML, Tompkins RG. A quantitative model of invasive Pseudomonas infection in burn injury. J Burn Care Rehabil. 1994 May-Jun; 15(3):232-5.
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Rotem A, Toner M, Bhatia S, Foy BD, Tompkins RG, Yarmush ML. Oxygen is a factor determining in vitro tissue assembly: Effects on attachment and spreading of hepatocytes. Biotechnol Bioeng. 1994 Mar 25; 43(7):654-60.
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Foy BD, Toner M, Tompkins RG, Yarmush ML. Engineering organ perfusion protocols: NMR analysis of hepatocyte isolation from perfused rat liver. Biotechnol Bioeng. 1994 Mar 25; 43(7):661-72.
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Carter EA, Tompkins RG. Injury-induced inhibition of fat absorption. J Burn Care Rehabil. 1994 Mar-Apr; 15(2):154-7.
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Ryan CM, Bailey SH, Carter EA, Schoenfeld DA, Tompkins RG. Additive effects of thermal injury and infection on gut permeability. Arch Surg. 1994 Mar; 129(3):325-8.
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Berthiaume F, Ezzell RM, Toner M, Yarmush ML, Tompkins RG. Transport of fluorescent dextrans across the rat ileum after cutaneous thermal injury. Crit Care Med. 1994 Mar; 22(3):455-64.
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Sheridan RL, Tompkins RG, McManus WF, Pruitt BA. Intracompartmental sepsis in burn patients. J Trauma. 1994 Mar; 36(3):301-5.
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Lu XM, Fischman AJ, Jyawook SL, Hendricks K, Tompkins RG, Yarmush ML. Antisense DNA delivery in vivo: liver targeting by receptor-mediated uptake. J Nucl Med. 1994 Feb; 35(2):269-75.
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Tompkins RG. Human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome. Crit Care Med. 1994 Jan; 22(1):3.
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Sheridan RL, Tompkins RG, Burke JF. Prophylactic antibiotics and their role in the prevention of surgical wound infection. Adv Surg. 1994; 27:43-65.
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Sheridan RL, Tompkins RG, Burke JF. Management of burn wounds with prompt excision and immediate closure. J Intensive Care Med. 1994 Jan; 9(1):6-17.
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Ge Y, Ezzell RM, Tompkins RG, Warren HS. Cellular distribution of endotoxin after injection of chemically purified lipopolysaccharide differs from that after injection of live bacteria. J Infect Dis. 1994 Jan; 169(1):95-104.
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Babich JW, Graham W, Barrow SA, Dragotakes SC, Tompkins RG, Rubin RH, Fischman AJ. Technetium-99m-labeled chemotactic peptides: comparison with indium-111-labeled white blood cells for localizing acute bacterial infection in the rabbit. J Nucl Med. 1993 Dec; 34(12):2176-81.
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Carter EA, Khalid MA, Burke JF, Tompkins RG. Absence of change in hepatic lactate metabolism after burn injury. Burns. 1993 Dec; 19(6):475-8.
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Fischman AJ, Rauh D, Solomon H, Babich JW, Tompkins RG, Kroon D, Strauss HW, Rubin RH. In vivo bioactivity and biodistribution of chemotactic peptide analogs in nonhuman primates. J Nucl Med. 1993 Dec; 34(12):2130-4.
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Karlsson JO, Cravalho EG, Borel Rinkes IH, Tompkins RG, Yarmush ML, Toner M. Nucleation and growth of ice crystals inside cultured hepatocytes during freezing in the presence of dimethyl sulfoxide. Biophys J. 1993 Dec; 65(6):2524-36.
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Babich JW, Solomon H, Pike MC, Kroon D, Graham W, Abrams MJ, Tompkins RG, Rubin RH, Fischman AJ. Technetium-99m-labeled hydrazino nicotinamide derivatized chemotactic peptide analogs for imaging focal sites of bacterial infection. J Nucl Med. 1993 Nov; 34(11):1964-74.
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Ezzell RM, Toner M, Hendricks K, Dunn JC, Tompkins RG, Yarmush ML. Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes. Exp Cell Res. 1993 Oct; 208(2):442-52.
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Sheridan RL, Ryan CM, Tompkins RG. An effective technique of scrotal harvest. J Burn Care Rehabil. 1993 Sep-Oct; 14(5):557-8.
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Ezzell RM, Carter EA, Yarmush ML, Tompkins RG. Thermal injury-induced changes in the rat intestine brush border cytoskeleton. Surgery. 1993 Sep; 114(3):591-7.
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Foy BD, Lee J, Morgan J, Toner M, Tompkins RG, Yarmush ML. Optimization of hepatocyte attachment to microcarriers: Importance of oxygen. Biotechnol Bioeng. 1993 Aug 20; 42(5):579-88.
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Horwitz JI, Toner M, Tompkins RG, Yarmush ML. Immobilized IL-2 preserves the viability of an IL-2 dependent cell line. Mol Immunol. 1993 Aug; 30(11):1041-8.
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Sheridan RL, Ryan CM, Pasternack MS, Weber JM, Tompkins RG. Flavobacterial sepsis in massively burned pediatric patients. Clin Infect Dis. 1993 Aug; 17(2):185-7.
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Toner M, Cravalho EG, Stachecki J, Fitzgerald T, Tompkins RG, Yarmush ML, Armant DR. Nonequilibrium freezing of one-cell mouse embryos. Membrane integrity and developmental potential. Biophys J. 1993 Jun; 64(6):1908-21.
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Mester M, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD. Intestinal production of interleukin-1 alpha during endotoxemia in the mouse. J Surg Res. 1993 Jun; 54(6):584-91.
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Lee J, Morgan JR, Tompkins RG, Yarmush ML. Proline-mediated enhancement of hepatocyte function in a collagen gel sandwich culture configuration. FASEB J. 1993 Apr 1; 7(6):586-91.
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Dunn JC, Tompkins RG, Yarmush ML. Dynamics of transcriptional and translational processes in hepatocytes cultured in a collagen sandwich. Biotechnol Bioeng. 1993 Mar 5; 41(5):593-8.
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Ryan CM, Schmidt J, Lewandrowski K, Compton CC, Rattner DW, Warshaw AL, Tompkins RG. Gut macromolecular permeability in pancreatitis correlates with severity of disease in rats. Gastroenterology. 1993 Mar; 104(3):890-5.
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Sheridan RL, Ryan CM, Tompkins RG. Acute adrenal insufficiency in the burn intensive care unit. Burns. 1993 Feb; 19(1):63-6.
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Ryan CM, Carter EA, Jenkins RL, Sterling LM, Yarmush ML, Malt RA, Tompkins RG. Isolation and long-term culture of human hepatocytes. Surgery. 1993 Jan; 113(1):48-54.
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Sheridan RL, Sheridan MG, Tompkins RG. Dishwasher effluent burns in infants. Pediatrics. 1993 Jan; 91(1):142-4.
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Yarmush ML, Thorpe WP, Strong L, Rakestraw SL, Toner M, Tompkins RG. Antibody Targeted Photolysis. Crit Rev Ther Drug Carrier Syst. 1993; 10(3):197-252.
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Rotem A, Toner M, Tompkins RG, Yarmush ML. Oxygen uptake rates in cultured rat hepatocytes. Biotechnol Bioeng. 1992 Dec 5; 40(10):1286-91.
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Lu XM, Fischman AJ, Stevens E, Lee TT, Strong L, Tompkins RG, Yarmush ML. Sn-chlorin e6 antibacterial immunoconjugates. An in vitro and in vivo analysis. J Immunol Methods. 1992 Nov 25; 156(1):85-99.
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Tompkins RG. Fulminant hepatic failure treated with anti-endotoxin antibody. Crit Care Med. 1992 Nov; 20(11):1507.
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Ryan CM, Yarmush ML, Burke JF, Tompkins RG. Increased gut permeability early after burns correlates with the extent of burn injury. Crit Care Med. 1992 Nov; 20(11):1508-12.
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Trop M, Tompkins RG, Schiffrin EJ, Carter EA, Burke JF. Core body temperature responses immediately after cutaneous thermal injury in rats. J Burn Care Rehabil. 1992 Nov-Dec; 13(6):632-8.
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Yarmush ML, Toner M, Dunn JC, Rotem A, Hubel A, Tompkins RG. Hepatic tissue engineering. Development of critical technologies. Ann N Y Acad Sci. 1992 Oct 13; 665:238-52.
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Cannon JG, Friedberg JS, Gelfand JA, Tompkins RG, Burke JF, Dinarello CA. Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans. Crit Care Med. 1992 Oct; 20(10):1414-9.
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Dunn JC, Friedberg JS, Tompkins RG, Yarmush ML. Hepatocytes from rat liver perfusions. Physicochemical effects on polyribosome size. ASAIO J. 1992 Oct-Dec; 38(4):841-5.
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Millis JM, Tompkins RK, Zinner MJ, Longmire WP, Roslyn JJ. Management of bile duct strictures. An evolving strategy. Arch Surg. 1992 Sep; 127(9):1077-82; discussion 1082-4.
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Borel Rinkes IH, Toner M, Ezzell RM, Tompkins RG, Yarmush ML. Effects of dimethyl sulfoxide on cultured rat hepatocytes in sandwich configuration. Cryobiology. 1992 Aug; 29(4):443-53.
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Lee J, Morgan JR, Tompkins RG, Yarmush ML. The importance of proline on long-term hepatocyte function in a collagen gel sandwich configuration: regulation of protein secretion. Biotechnol Bioeng. 1992 Jun 20; 40(2):298-305.
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Bader A, Borel Rinkes IH, Closs EI, Ryan CM, Toner M, Cunningham JM, Tompkins RG, Yarmush ML. A stable long-term hepatocyte culture system for studies of physiologic processes: cytokine stimulation of the acute phase response in rat and human hepatocytes. Biotechnol Prog. 1992 May-Jun; 8(3):219-25.
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Ryan CM, Yarmush ML, Tompkins RG. Separation and quantitation of polyethylene glycols 400 and 3350 from human urine by high-performance liquid chromatography. J Pharm Sci. 1992 Apr; 81(4):350-2.
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Carter EA, Gonnella A, Tompkins RG. Increased transcellular permeability of rat small intestine after thermal injury. Burns. 1992 Apr; 18(2):117-20.
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Dunn JC, Tompkins RG, Yarmush ML. Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation. J Cell Biol. 1992 Feb; 116(4):1043-53.
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Shockley TR, Lin K, Sung C, Nagy JA, Tompkins RG, Dedrick RL, Dvorak HF, Yarmush ML. A quantitative analysis of tumor specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levels. Cancer Res. 1992 Jan 15; 52(2):357-66.
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Shockley TR, Lin K, Nagy JA, Tompkins RG, Yarmush ML, Dvorak HF. Spatial distribution of tumor-specific monoclonal antibodies in human melanoma xenografts. Cancer Res. 1992 Jan 15; 52(2):367-76.
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Borel Rinkes IH, Toner M, Sheeha SJ, Tompkins RG, Yarmush ML. Long-term functional recovery of hepatocytes after cryopreservation in a three-dimensional culture configuration. Cell Transplant. 1992; 1(4):281-92.
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Tompkins RG, Burke JF. Burn wound closure using permanent skin replacement materials. World J Surg. 1992 Jan-Feb; 16(1):47-52.
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Rakestraw SL, Ford WE, Tompkins RG, Rodgers MA, Thorpe WP, Yarmush ML. Antibody-targeted photolysis: in vitro immunological, photophysical, and cytotoxic properties of monoclonal antibody-dextran-Sn(IV) chlorin e6 immunoconjugates. Biotechnol Prog. 1992 Jan-Feb; 8(1):30-9.
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Saunders KD, Tompkins RK, Cates JA, Longmire WP, Roslyn JJ. The natural history of carcinoma of the bile duct in patients less than forty-five years of age. Surg Gynecol Obstet. 1992 Jan; 174(1):1-6.
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Yarmush ML, Dunn JC, Tompkins RG. Assessment of artificial liver support technology. Cell Transplant. 1992; 1(5):323-41.
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Hubel A, Toner M, Cravalho EG, Yarmush ML, Tompkins RG. Intracellular ice formation during the freezing of hepatocytes cultured in a double collagen gel. Biotechnol Prog. 1991 Nov-Dec; 7(6):554-9.
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Harris CL, Toner M, Hubel A, Cravalho EG, Yarmush ML, Tompkins RG. Cryopreservation of isolated hepatocytes: intracellular ice formation under various chemical and physical conditions. Cryobiology. 1991 Oct; 28(5):436-44.
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Saunders K, Tompkins R, Longmire W, Roslyn J. Bile duct carcinoma in the elderly. A rationale for surgical management. Arch Surg. 1991 Oct; 126(10):1186-90; discussion 1190-1.
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Tompkins RG, Fischman AJ, Yarmush ML. Imaging infections with antibodies. A method to localize occult infections. Chest. 1991 Sep; 100(3 Suppl):169S-172S.
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Dunn JC, Tompkins RG, Yarmush ML. Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol Prog. 1991 May-Jun; 7(3):237-45.
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Tompkins RG. Quantitative analysis of blood vessel permeability of squirrel monkeys. Am J Physiol. 1991 Apr; 260(4 Pt 2):H1194-204.
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Shockley TR, Lin K, Nagy JA, Tompkins RG, Dvorak HF, Yarmush ML. Penetration of tumor tissue by antibodies and other immunoproteins. Ann N Y Acad Sci. 1991; 618:367-82.
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Domingues RC, Mikulis D, Swearingen B, Tompkins R, Rosen BR. Subcutaneous sacrococcygeal myxopapillary ependymoma: CT and MR findings. AJNR Am J Neuroradiol. 1991 Jan-Feb; 12(1):171-2.
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Friedberg JS, Tompkins RG, Rakestraw SL, Warren SW, Fischman AJ, Yarmush ML. Antibody-targeted photolysis. Bacteriocidal effects of Sn (IV) chlorin e6-dextran-monoclonal antibody conjugates. Ann N Y Acad Sci. 1991; 618:383-93.
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Shockley TR, Mandeville JT, Tompkins RG, Yarmush ML. Equilibrium binding characteristics of monoclonal antibodies recognizing melanoma cell surface antigens. Hybridoma. 1990 Dec; 9(6):527-44.
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Tompkins RG, Burke JF. Progress in burn treatment and the use of artificial skin. World J Surg. 1990 Nov-Dec; 14(6):819-24.
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Koebe HG, Dunn JC, Toner M, Sterling LM, Hubel A, Cravalho EG, Yarmush ML, Tompkins RG. A new approach to the cryopreservation of hepatocytes in a sandwich culture configuration. Cryobiology. 1990 Oct; 27(5):576-84.
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Tompkins RK. Laparoscopic cholecystectomy. Threat or opportunity? Arch Surg. 1990 Oct; 125(10):1245.
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Morrel EM, Tompkins RG, Fischman AJ, Wilkinson RA, Yarmush ML. Imaging infections with antibodies. A quantitative autoradiographic analysis. J Immunol Methods. 1990 Jun 12; 130(1):39-48.
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Carter EA, Hatz RA, Yarmush ML, Tompkins RG. Injury-induced inhibition of small intestinal protein and nucleic acid synthesis. Gastroenterology. 1990 Jun; 98(6):1445-51.
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Rakestraw SL, Tompkins RG, Yarmush ML. Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier. Proc Natl Acad Sci U S A. 1990 Jun; 87(11):4217-21.
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Tompkins RK, Saunders K, Roslyn JJ, Longmire WP. Changing patterns in diagnosis and management of bile duct cancer. Ann Surg. 1990 May; 211(5):614-20; discussion 620-1.
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Rakestraw SL, Tompkins RG, Yarmush ML. Preparation and characterization of immunoconjugates for antibody-targeted photolysis. Bioconjug Chem. 1990 May-Jun; 1(3):212-21.
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Carter EA, Tompkins RG, Schiffrin E, Burke JF. Cutaneous thermal injury alters macromolecular permeability of rat small intestine. Surgery. 1990 Mar; 107(3):335-41.
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Cannon JG, Tompkins RG, Gelfand JA, Michie HR, Stanford GG, van der Meer JW, Endres S, Lonnemann G, Corsetti J, Chernow B, et al. Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. J Infect Dis. 1990 Jan; 161(1):79-84.
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Morrell EM, Tompkins RG, Fischman AJ, Wilkinson RA, Burke JF, Rubin RH, Strauss HW, Yarmush ML. Autoradiographic method for quantitation of radiolabeled proteins in tissues using indium-111. J Nucl Med. 1989 Sep; 30(9):1538-45.
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Tompkins RG, Hilton JF, Burke JF, Schoenfeld DA, Hegarty MT, Bondoc CC, Quinby WC, Behringer GE, Ackroyd FW. Increased survival after massive thermal injuries in adults: preliminary report using artificial skin. Crit Care Med. 1989 Aug; 17(8):734-40.
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Tompkins RG, Yarmush ML, Schnitzer JJ, Colton CK, Smith KA, Stemerman MB. Low-density lipoprotein transport in blood vessel walls of squirrel monkeys. Am J Physiol. 1989 Aug; 257(2 Pt 2):H452-64.
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Tompkins RG, Schnitzer JJ, Yarmush ML. Macromolecular transport within heart valves. Circ Res. 1989 Jun; 64(6):1213-23.
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Carter EA, Kirkham SE, Tompkins RG, Burke JF. Inhibition of in vivo DNA synthesis in regenerating rat liver following thermal injury. Biochem Biophys Res Commun. 1989 Apr 14; 160(1):196-201.
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Dunn JC, Yarmush ML, Koebe HG, Tompkins RG. Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB J. 1989 Feb; 3(2):174-7.
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Moncure AC, Tompkins RG, Athanasoulis CA, Welch CE. Occult gastrointestinal bleeding: newer techniques and diagnosis and therapy. Adv Surg. 1989; 22:141-77.
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Tompkins RG, Remensnyder JP, Burke JF, Tompkins DM, Hilton JF, Schoenfeld DA, Behringer GE, Bondoc CC, Briggs SE, Quinby WC. Significant reductions in mortality for children with burn injuries through the use of prompt eschar excision. Ann Surg. 1988 Nov; 208(5):577-85.
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Bennion RS, Thompson JE, Tompkins RK. Agenesis of the gallbladder without extrahepatic biliary atresia. Arch Surg. 1988 Oct; 123(10):1257-60.
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Carter EA, Tompkins RG, Yarmush ML, Walker WA, Burke JF. Redistribution of blood flow after thermal injury and hemorrhagic shock. J Appl Physiol. 1988 Oct; 65(4):1782-8.
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Lai EC, Doty JE, Irving C, Tompkins RK. Primary adenocarcinoma of the duodenum: analysis of survival. World J Surg. 1988 Oct; 12(5):695-9.
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Tompkins RG, Schnitzer JJ, Yarmush ML, Colton CK, Smith KA. Measurement of 125I-low density lipoprotein uptake in selected tissues of the squirrel monkey by quantitative autoradiography. Am J Pathol. 1988 Sep; 132(3):526-42.
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Carter EA, Tompkins RG, Burke JF. Hepatic and intestinal blood flow following thermal injury. J Burn Care Rehabil. 1988 Jul-Aug; 9(4):347-50.
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Ch SW, Carter EA, Tompkins RG, Burke JF. Increase of sialyltransferase activity in the small intestine following thermal injury in rats. Biochem Biophys Res Commun. 1988 May 31; 153(1):377-81.
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Tompkins RG, McCabe CJ, Burke JF, Keating MA, Wright CD. Rectal necrosis after pelvic crush injury. J Trauma. 1988 May; 28(5):697-9.
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Tompkins RK. Treatment and prognosis in bile duct cancer. World J Surg. 1988 Feb; 12(1):109-10.
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Tompkins RG, Carter EA, Carlson JD, Yarmush ML. Enzymatic function of alginate immobilized rat hepatocytes. Biotechnol Bioeng. 1988 Jan; 31(1):11-8.
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Lipscomb MF, Alvarellos T, Toews GB, Tompkins R, Evans Z, Koo G, Kumar V. Role of natural killer cells in resistance to Cryptococcus neoformans infections in mice. Am J Pathol. 1987 Aug; 128(2):354-61.
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Hiatt JR, Tompkins RK. The importance of nonoperative trauma management in postgraduate surgical education. J Trauma. 1987 Jul; 27(7):769-73.
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Lai EC, King W, Longmire WP, Tompkins RK. Pancreaticojejunostomy after Whipple's operation--in vivo evaluation of long-term patency: a preliminary report. Surgery. 1987 May; 101(5):544-8.
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Lai EC, Tompkins RK, Mann LL, Roslyn JJ. Proximal bile duct cancer. Quality of survival. Ann Surg. 1987 Feb; 205(2):111-8.
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Tompkins RK, Doty JE. Modern management of biliary tract stone disease. Adv Surg. 1987; 20:279-301.
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Tompkins RG, Burke JF, Schoenfeld DA, Bondoc CC, Quinby WC, Behringer GC, Ackroyd FW. Prompt eschar excision: a treatment system contributing to reduced burn mortality. A statistical evaluation of burn care at the Massachusetts General Hospital (1974-1984). Ann Surg. 1986 Sep; 204(3):272-81.
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Pitt HA, Korzelius J, Tompkins RK. Management of hepatic echinococcosis in Southern California. Am J Surg. 1986 Jul; 152(1):110-5.
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Lai EC, Tompkins RK. Heterotopic pancreas. Review of a 26 year experience. Am J Surg. 1986 Jun; 151(6):697-700.
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Lai EC, Tompkins RK. Water and electrolyte absorption from a human Thiry-Vella ileal loop. Responses to systemic administration of gastrin, glucagon, secretin, and cholecystokinin. Ann Surg. 1986 Apr; 203(4):434-8.
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Conter RL, Pitt HA, Tompkins RK, Longmire WP. Differentiation of pyogenic from amebic hepatic abscesses. Surg Gynecol Obstet. 1986 Feb; 162(2):114-20.
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Tompkins RG, Burke JF. Burn therapy 1985: acute management. Intensive Care Med. 1986; 12(4):289-95.
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Eto T, Tompkins RK. Further studies on the inhibition of pepsin by bile salts. Ann Surg. 1986 Jan; 203(1):8-12.
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Tompkins RG, Warshaw AL. Improved management of the perineal wound after proctectomy. Ann Surg. 1985 Dec; 202(6):760-5.
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Reinschmidt D, Friedman J, Hauth J, Ratner E, Cohen M, Miller M, Krotoski D, Tompkins R. Gene-centromere mapping in Xenopus laevis. J Hered. 1985 Sep-Oct; 76(5):345-7.
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Roslyn JJ, Kuchenbecker S, Longmire WP, Tompkins RK. Floating tumor debris. A cause of intermittent biliary obstruction. Arch Surg. 1984 Nov; 119(11):1312-5.
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Tompkins R, Szaro B, Reinschmidt D, Kaye C, Ide C. Effects of alterations of cell size and number on the structure and function of the Xenopus laevis nervous system. Adv Exp Med Biol. 1984; 181:135-46.
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Thompson HH, Tompkins RK, Longmire WP. Major hepatic resection. A 25-year experience. Ann Surg. 1983 Apr; 197(4):375-88.
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Gibbs DA, Spellacy E, Tompkins R, Watts RW, Mowbray JF. A clinical trial of fibroblast transplantation for the treatment of mucopolysaccharidoses. J Inherit Metab Dis. 1983; 6(2):62-81.
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Taylor JR, Tompkins R, Demers R, Anderson D. Electroconvulsive therapy and memory dysfunction: is there evidence for prolonged defects? Biol Psychiatry. 1982 Oct; 17(10):1169-93.
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Pitt HA, Thompson HH, Tompkins RK, Longmire WP. Primary sclerosing cholangitis: results of an aggressive surgical approach. Ann Surg. 1982 Sep; 196(3):259-68.
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Thompson HH, Pitt HA, Tompkins RK, Longmire WP. Primary sclerosing cholangitis: a heterogenous disease. Ann Surg. 1982 Aug; 196(2):127-36.
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Thompson JE, Tompkins RK, Longmire WP. Factors in management of acute cholangitis. Ann Surg. 1982 Feb; 195(2):137-45.
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Logan SE, Voet RL, Tompkins RK. The malignant potential of mucinous cysts of the pancreas. West J Med. 1982 Feb; 136(2):157-62.
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Traverso LW, Abou-Zamzam AM, Maxwell DS, Lacy SM, Tompkins RK. The effect of total parenteral nutrition or elemental diet on pancreatic proteolytic activity and ultrastructure. JPEN J Parenter Enteral Nutr. 1981 Nov-Dec; 5(6):496-500.
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Busuttil RW, Davidson RK, Fine M, Tompkins RK. Effect of prophylactic antibiotics in acute nonperforated appendicitis: a prospective, randomized, double-blind clinical study. Ann Surg. 1981 Oct; 194(4):502-9.
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Tompkins RK, Thomas D, Wile A, Longmire WP. Prognostic factors in bile duct carcinoma: analysis of 96 cases. Ann Surg. 1981 Oct; 194(4):447-57.
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Diehr P, Wood RW, Barr V, Wolcott B, Slay L, Tompkins RK. Acute headaches: presenting symptoms and diagnostic rules to identify patients with tension and migraine headache. J Chronic Dis. 1981; 34(4):147-58.
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Lazar HL, DeLand EC, Tompkins RK. Clinical performance versus in-training examinations as measures of surgical competence. Surgery. 1980 Apr; 87(4):357-62.
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Traverso LW, Tompkins RK, Urrea PT, Longmire WP. Surgical treatment of chronic pancreatitis. Twenty-two years' experience. Ann Surg. 1979 Sep; 190(3):312-9.
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Madura JA, Loomis RC, Harris RA, Grosfeld J, Tompkins RK. Relationship of obesity to bile lithogenicity in man. Ann Surg. 1979 Jan; 189(1):106-11.
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Tompkins RK, Waisman J, Watt CM, Corlin R, Keith R. Absence of mucosal atrophy in human small intestine after prolonged isolation. Gastroenterology. 1977 Dec; 73(6):1406-9.
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Porter JR, Kastin AJ, Pelle-Day G, Tompkins RG. Regional in vitro uptake of a synthetic 3H-labeled-melanin into rat brain. Brain Res Bull. 1977 Nov-Dec; 2(6):401-4.
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Traverso LW, Ferrari BT, Buckberg GD, Tompkins RK. Eelvated postoperative renal clearance of amylase without pancreatitis after cardiopulmonary bypass. Am J Surg. 1977 Mar; 133(3):298-303.
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Kastin AJ, Kuzemchak B, Tompkins RG, Schally AV, Miller MC. Melanin in the rat brain. Brain Res Bull. 1976 Nov-Dec; 1(6):567-72.
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Traverso LW, Longmire WP, Tompkins RK. Evaluation of experimental canine pancreatitis. J Surg Res. 1976 Oct; 21(4):247-53.
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Tompkins RK, Johnson J, Storm FK, Longmire WP. Operative endoscopy in the management of biliary tract neoplasms. Am J Surg. 1976 Aug; 132(2):174-82.
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McAvoy JM, Tompkins RK, Longmire WP. Benign hepatic tumors and their association with oral contraceptives. Arch Surg. 1976 Jul; 111(7):761-7.
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Kraft AR, Saletta JD, Moss GS, Herman CM, Tompkins RK. A critical appraisal of the effectiveness of scientific presentations. J Surg Res. 1976 Apr; 20(4):377-9.
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O'Connell TX, Kadell B, Tompkins RK. Ischemia of the colon. Surg Gynecol Obstet. 1976 Mar; 142(3):337-42.
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Tompkins RK. Part II. The systemic treatment of gallstones. Adv Surg. 1976; 10:87-98.
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Walsh BT, Bookheim WW, Johnson RC, Tompkins RK. Recognition of streptococcal pharyngitis in adults. Arch Intern Med. 1975 Nov; 135(11):1493-7.
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Longmire WP, Tompkins RK. Lesions of the segmental and lobar hepatic ducts. Ann Surg. 1975 Oct; 182(4):478-95.
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Wilbur BG, Gomez FC, Tompkins RK. Canine gallbladder bile. Effects of proximal gastric vagotomy, truncal vagotomy, and truncal vagotomy with pyloroplasty on volume and composition. Arch Surg. 1975 Jul; 110(7):792-6.
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Heidemann SR, Townsend J, Tompkins R. Synthesis of soluble protein in oocytes of Xenopus laevis. J Exp Zool. 1975 Feb; 191(2):253-60.
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Albritton DR, Tompkins RK, Longmire WP. Hepatic cell adenoma: A report of four cases. Ann Surg. 1974 Jul; 180(1):14-9.
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Smith GA, Tompkins RK. Biliary magnesium loss in the postoperative patient. Arch Surg. 1974 Jul; 109(1):77-9.
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Longmire WP, Trout HH, Greenfield J, Tompkins RK. Elective hepatic surgery. Ann Surg. 1974 May; 179(5):712-21.
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Tompkins RK, King W. Investigations of the enterobiliary metabolism of lecithin. Surgery. 1974 Feb; 75(2):243-52.
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Aston SJ, Tompkins RK. Granular cell myoblastoma of stomach. Ann Surg. 1973 Feb; 177(2):228-31.
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Tompkins RK, Kuchenbecker SL. Relationship of cyclic AMP to secretin stimulation of the pancreas. J Surg Res. 1973 Feb; 14(2):172-6.
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Tompkins RK, Adams JR. Macroamylasemia in the postoperative patient. A source of confusion and concern. Arch Surg. 1972 Oct; 105(4):630-2.
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Tompkins RK, Kraft AR, Zollinger RM. Double-lumen gastrojejunostomy tube for simplified postoperative management. Arch Surg. 1972 Jul; 105(1):121-2.
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Kakos GS, Tompkins RK, Turnipseed W, Zollinger RM. Operative cholangiography during routine cholecystectomy: a review of 3,012 cases. Arch Surg. 1972 Apr; 104(4):484-8.
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Tompkins RK, Kraft AR, Zimmerman E, Lichtenstein JE, Zollinger RM. Clinical and biochemical evidence of increased gallstone formation after complete vagotomy. Surgery. 1972 Feb; 71(2):196-200.
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Tompkins RK, Burke LG, Zollinger RM, Cornwell DG. Relationship of biliary phospholipid and cholesterol concentrations to the occurrence and dissolution of human gallstones. Ann Surg. 1970 Dec; 172(6):936-45.
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Van Oss CJ, McConnell CR, Tompkins RK, Bronson PM. A membrane for the rapid concentration of dilute protein samples in an ultrafilter. Clin Chem. 1969 Aug; 15(8):699-707.
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Tompkins RK, Kraft AR, Zollinger RM. Secretin-like choleresis produced by a diarrheogenic non-beta islet cell tumor of the pancreas. Surgery. 1969 Jul; 66(1):131-7.
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Caskey T, Scolnick E, Tompkins R, Goldstein J, Milman G. Peptide chain termination, codon, protein factor, and ribosomal requirements. Cold Spring Harb Symp Quant Biol. 1969; 34:479-88.
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Zollinger RM, Tompkins RK, Amerson JR, Endahl GL, Kraft AR, Moore FT. Identification of the diarrheogenic hormone associated with non-beta islet cell tumors of the pancreas. Ann Surg. 1968 Sep; 168(3):502-21.
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Kraft AR, Tompkins RK, Jesseph JE. Peritoneal electrolyte absorption: analysis of portal, systemic venous, and lymphatic transport. Surgery. 1968 Jul; 64(1):148-53.
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Mezick JA, Tompkins RK, Cornwell DG. Absorption and intestinal lymphatic transport of 14-C-menadione. Life Sci. 1968 Feb 1; 7(3):153-8.
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Fonkalsrud EW, Tompkins R, Clatworthy HW. Abdominal manifestations of situs inversus in infants and children. Arch Surg. 1966 May; 92(5):791-5.
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LYONS WS, TOMPKINS RG, KIRKLIN JW, WOOD EH. Early and late hemodynamic effects of mitral commissurotomy. J Lab Clin Med. 1959 Apr; 53(4):499-516.
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WARNER HR, SWAN HJ, CONNOLLY DC, TOMPKINS RG, WOOD EH. Quantitation of beat-to-beat changes in stroke volume from the aortic pulse contour in man. J Appl Physiol. 1953 Mar; 5(9):495-507.
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CONNOLLY DC, TOMPKINS RG, LEV R, KIRKLIN JW, WOOD EH. Pulmonary artery wedge pressures in mitral valve disease; relationship to left atrial pressures. Proc Staff Meet Mayo Clin. 1953 Feb 11; 28(3):72-8.
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KIRKLIN JW, OPENSHAW CR, TOMPKINS RG. Surgical treatment of infundibular stenosis with intact ventricular septum. Ann Surg. 1953 Feb; 137(2):228-31.
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