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George A. Jacoby, M.D.

TitleAssociate Professor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressLahey Clinic Medical Center
Research
41 Mall Rd
Burlington MA 01805
Phone781/744-2928
Fax781/744-5486

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Jacoby GA, Hooper DC. Phylogenetic analysis of chromosomally determined qnr and related proteins. Antimicrob Agents Chemother. 2013 Apr; 57(4):1930-4.
    View in: PubMed
  2. Bush K, Courvalin P, Dantas G, Davies J, Eisenstein B, Huovinen P, Jacoby GA, Kishony R, Kreiswirth BN, Kutter E, Lerner SA, Levy S, Lewis K, Lomovskaya O, Miller JH, Mobashery S, Piddock LJ, Projan S, Thomas CM, Tomasz A, Tulkens PM, Walsh TR, Watson JD, Witkowski J, Witte W, Wright G, Yeh P, Zgurskaya HI. Tackling antibiotic resistance. Nat Rev Microbiol. 2011 Dec; 9(12):894-6.
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  3. Okumura R, Liao CH, Gavin M, Jacoby GA, Hooper DC. Quinolone induction of qnrVS1 in Vibrio splendidus and plasmid-carried qnrS1 in Escherichia coli, a mechanism independent of the SOS system. Antimicrob Agents Chemother. 2011 Dec; 55(12):5942-5.
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  4. Jacoby GA, Griffin CM, Hooper DC. Citrobacter spp. as a source of qnrB Alleles. Antimicrob Agents Chemother. 2011 Nov; 55(11):4979-84.
    View in: PubMed
  5. Vetting MW, Hegde SS, Wang M, Jacoby GA, Hooper DC, Blanchard JS. Structure of QnrB1, a plasmid-mediated fluoroquinolone resistance factor. J Biol Chem. 2011 Jul 15; 286(28):25265-73.
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  6. Kim HB, Park CH, Gavin M, Jacoby GA, Hooper DC. Cold shock induces qnrA expression in Shewanella algae. Antimicrob Agents Chemother. 2011 Jan; 55(1):414-6.
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  7. Xu X, Lin D, Yan G, Ye X, Wu S, Guo Y, Zhu D, Hu F, Zhang Y, Wang F, Jacoby GA, Wang M. vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium. Antimicrob Agents Chemother. 2010 Nov; 54(11):4643-7.
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  8. Bush K, Jacoby GA. Updated functional classification of beta-lactamases. Antimicrob Agents Chemother. 2010 Mar; 54(3):969-76.
    View in: PubMed
  9. Kim HB, Wang M, Ahmed S, Park CH, LaRocque RC, Faruque AS, Salam MA, Khan WA, Qadri F, Calderwood SB, Jacoby GA, Hooper DC. Transferable quinolone resistance in Vibrio cholerae. Antimicrob Agents Chemother. 2010 Feb; 54(2):799-803.
    View in: PubMed
  10. Strahilevitz J, Jacoby GA, Hooper DC, Robicsek A. Plasmid-mediated quinolone resistance: a multifaceted threat. Clin Microbiol Rev. 2009 Oct; 22(4):664-89.
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  11. Kim HB, Wang M, Park CH, Kim EC, Jacoby GA, Hooper DC. oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae. Antimicrob Agents Chemother. 2009 Aug; 53(8):3582-4.
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  12. Bush K, Jacoby GA, Amicosante G, Bonomo RA, Bradford P, Cornaglia G, Garau J, Giamarellou H, Jarlier V, Martinez-Martinez L, Miriagou V, Palzkill T, Pascual A, Rodriguez-Baño J, Rossolini GM, Sougakoff W, Vatopoulos A. Comment on: Redefining extended-spectrum beta-lactamases: balancing science and clinical need. J Antimicrob Chemother. 2009 Jul; 64(1):212-3; author reply 213-5.
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  13. Jacoby GA, Gacharna N, Black TA, Miller GH, Hooper DC. Temporal appearance of plasmid-mediated quinolone resistance genes. Antimicrob Agents Chemother. 2009 Apr; 53(4):1665-6.
    View in: PubMed
  14. Jacoby GA. AmpC beta-lactamases. Clin Microbiol Rev. 2009 Jan; 22(1):161-82, Table of Contents.
    View in: PubMed
  15. Kim HB, Park CH, Kim CJ, Kim EC, Jacoby GA, Hooper DC. Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period. Antimicrob Agents Chemother. 2009 Feb; 53(2):639-45.
    View in: PubMed
  16. Wang M, Jacoby GA, Mills DM, Hooper DC. SOS regulation of qnrB expression. Antimicrob Agents Chemother. 2009 Feb; 53(2):821-3.
    View in: PubMed
  17. Vetting MW, Park CH, Hegde SS, Jacoby GA, Hooper DC, Blanchard JS. Mechanistic and structural analysis of aminoglycoside N-acetyltransferase AAC(6')-Ib and its bifunctional, fluoroquinolone-active AAC(6')-Ib-cr variant. Biochemistry. 2008 Sep 16; 47(37):9825-35.
    View in: PubMed
  18. Jacoby G, Cattoir V, Hooper D, Martínez-Martínez L, Nordmann P, Pascual A, Poirel L, Wang M. qnr Gene nomenclature. Antimicrob Agents Chemother. 2008 Jul; 52(7):2297-9.
    View in: PubMed
  19. Whichard JM, Gay K, Stevenson JE, Joyce KJ, Cooper KL, Omondi M, Medalla F, Jacoby GA, Barrett TJ. Human Salmonella and concurrent decreased susceptibility to quinolones and extended-spectrum cephalosporins. Emerg Infect Dis. 2007 Nov; 13(11):1681-8.
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  20. Shara MM, Martin CD, Seibert M, Rich RM, Salim S, Reitzel D, Schiminovich D, Deliyannis CP, Sarrazine AR, Kulkarni SR, Ofek EO, Brosch N, Lépine S, Zurek D, De Marco O, Jacoby G. An ancient nova shell around the dwarf nova Z Camelopardalis. Nature. 2007 Mar 8; 446(7132):159-62.
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  21. Robicsek A, Jacoby GA, Hooper DC. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis. 2006 Oct; 6(10):629-40.
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  22. Park CH, Robicsek A, Jacoby GA, Sahm D, Hooper DC. Prevalence in the United States of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme. Antimicrob Agents Chemother. 2006 Nov; 50(11):3953-5.
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  23. Robicsek A, Strahilevitz J, Sahm DF, Jacoby GA, Hooper DC. qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States. Antimicrob Agents Chemother. 2006 Aug; 50(8):2872-4.
    View in: PubMed
  24. Gay K, Robicsek A, Strahilevitz J, Park CH, Jacoby G, Barrett TJ, Medalla F, Chiller TM, Hooper DC. Plasmid-mediated quinolone resistance in non-Typhi serotypes of Salmonella enterica. Clin Infect Dis. 2006 Aug 1; 43(3):297-304.
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  25. Jacoby GA, Walsh KE, Walker VJ. Identification of extended-spectrum, AmpC, and carbapenem- hydrolyzing beta-lactamases in Escherichia coli and Klebsiella pneumoniae by disk tests. J Clin Microbiol. 2006 Jun; 44(6):1971-6.
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  26. Jacoby GA. Beta-lactamase nomenclature. Antimicrob Agents Chemother. 2006 Apr; 50(4):1123-9.
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  27. Jacoby GA, Walsh KE, Mills DM, Walker VJ, Oh H, Robicsek A, Hooper DC. qnrB, another plasmid-mediated gene for quinolone resistance. Antimicrob Agents Chemother. 2006 Apr; 50(4):1178-82.
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  28. Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, Bush K, Hooper DC. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med. 2006 Jan; 12(1):83-8.
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  29. Jacoby GA, Bush K. Beta-lactamase nomenclature. J Clin Microbiol. 2005 Dec; 43(12):6220.
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  30. Jacoby GA. Mechanisms of resistance to quinolones. Clin Infect Dis. 2005 Jul 15; 41 Suppl 2:S120-6.
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  31. Robicsek A, Sahm DF, Strahilevitz J, Jacoby GA, Hooper DC. Broader distribution of plasmid-mediated quinolone resistance in the United States. Antimicrob Agents Chemother. 2005 Jul; 49(7):3001-3.
    View in: PubMed
  32. Tran JH, Jacoby GA, Hooper DC. Interaction of the plasmid-encoded quinolone resistance protein QnrA with Escherichia coli topoisomerase IV. Antimicrob Agents Chemother. 2005 Jul; 49(7):3050-2.
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  33. Jacoby GA, Munoz-Price LS. The new beta-lactamases. N Engl J Med. 2005 Jan 27; 352(4):380-91.
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  34. Tran JH, Jacoby GA, Hooper DC. Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase. Antimicrob Agents Chemother. 2005 Jan; 49(1):118-25.
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  35. Jacoby GA, Mills DM, Chow N. Role of beta-lactamases and porins in resistance to ertapenem and other beta-lactams in Klebsiella pneumoniae. Antimicrob Agents Chemother. 2004 Aug; 48(8):3203-6.
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  36. Wang M, Sahm DF, Jacoby GA, Zhang Y, Hooper DC. Activities of newer quinolones against Escherichia coli and Klebsiella pneumoniae containing the plasmid-mediated quinolone resistance determinant qnr. Antimicrob Agents Chemother. 2004 Apr; 48(4):1400-1.
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  37. Wang M, Sahm DF, Jacoby GA, Hooper DC. Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States. Antimicrob Agents Chemother. 2004 Apr; 48(4):1295-9.
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  38. Alvarez M, Tran JH, Chow N, Jacoby GA. Epidemiology of conjugative plasmid-mediated AmpC beta-lactamases in the United States. Antimicrob Agents Chemother. 2004 Feb; 48(2):533-7.
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  39. Munoz LS, Jacoby G, Snydman DR. Extended-spectrum beta-lactamases. 2004.
  40. Wang M, Tran JH, Jacoby GA, Zhang Y, Wang F, Hooper DC. Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China. Antimicrob Agents Chemother. 2003 Jul; 47(7):2242-8.
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  41. Jacoby GA, Vacheva-Dobrevsky R. Epidemiology of extended-spectrum beta-lactamases in Sofia, Bulgaria. Eur J Clin Microbiol Infect Dis. 2003 Jun; 22(6):385-8.
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  42. Martínez-Martínez L, Pascual A, García I, Tran J, Jacoby GA. Interaction of plasmid and host quinolone resistance. J Antimicrob Chemother. 2003 Apr; 51(4):1037-9.
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  43. Jacoby GA, Chow N, Waites KB. Prevalence of plasmid-mediated quinolone resistance. Antimicrob Agents Chemother. 2003 Feb; 47(2):559-62.
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  44. Levison ME, Mailapur YV, Pradhan SK, Jacoby GA, Adams P, Emery CL, May PL, Pitsakis PG. Regional occurrence of plasmid-mediated SHV-7, an extended-spectrum beta-lactamase, in Enterobacter cloacae in Philadelphia Teaching Hospitals. Clin Infect Dis. 2002 Dec 15; 35(12):1551-4.
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  45. Arduino SM, Roy PH, Jacoby GA, Orman BE, Pineiro SA, Centron D. blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513. Antimicrob Agents Chemother. 2002 Jul; 46(7):2303-6.
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  46. Rasheed JK, Anderson GJ, Queenan AM, Biddle JW, Oliver A, Jacoby GA, Bush K, Tenover FC. TEM-71, a novel plasmid-encoded, extended-spectrum beta-lactamase produced by a clinical isolate of Klebsiella pneumoniae. Antimicrob Agents Chemother. 2002 Jun; 46(6):2000-3.
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  47. Tran JH, Jacoby GA. Mechanism of plasmid-mediated quinolone resistance. Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8):5638-42.
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  48. Philippon A, Arlet G, Jacoby GA. Plasmid-determined AmpC-type beta-lactamases. Antimicrob Agents Chemother. 2002 Jan; 46(1):1-11.
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  49. Pai H, Lee HJ, Choi EH, Kim J, Jacoby GA. Evolution of TEM-related extended-spectrum beta-lactamases in Korea. Antimicrob Agents Chemother. 2001 Dec; 45(12):3651-3.
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  50. Pai H, Jacoby GA. Sequences of the NPS-1 and TLE-1 beta-lactamase genes. Antimicrob Agents Chemother. 2001 Oct; 45(10):2947-8.
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  51. Pai H, Choi EH, Lee HJ, Hong JY, Jacoby GA. Identification of CTX-M-14 extended-spectrum beta-lactamase in clinical isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in Korea. J Clin Microbiol. 2001 Oct; 39(10):3747-9.
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  52. Rasheed JK, Anderson GJ, Yigit H, Queenan AM, Doménech-Sánchez A, Swenson JM, Biddle JW, Ferraro MJ, Jacoby GA, Tenover FC. Characterization of the extended-spectrum beta-lactamase reference strain, Klebsiella pneumoniae K6 (ATCC 700603), which produces the novel enzyme SHV-18. Antimicrob Agents Chemother. 2000 Sep; 44(9):2382-8.
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  53. Jacoby GA, Tran J. Sequence of the MIR-1 beta-lactamase gene. Antimicrob Agents Chemother. 1999 Jul; 43(7):1759-60.
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  54. Martínez-Martínez L, Pascual A, Hernández-Allés S, Alvarez-Díaz D, Suárez AI, Tran J, Benedí VJ, Jacoby GA. Roles of beta-lactamases and porins in activities of carbapenems and cephalosporins against Klebsiella pneumoniae. Antimicrob Agents Chemother. 1999 Jul; 43(7):1669-73.
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  55. Jacoby GA. History of antimicrobial agents and chemotherapy from 1972 to 1998 Antimicrob Agents Chemother. 1999 May; 43(5):999-1002.
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  56. Jacoby GA. Mechanisms of antibacterial action and resistance. Root RK, Waldvogel F, Corey L, Stamm W, eds. Clinical infectious diseases: a practical approach. 1999; 209-15.
  57. Jacoby GA. Development of resistance in gram-negative pathogens. Extended-spectrum beta-lactamases. Emerging pathogens in infectious disease. A hospital practice special report. 1999; 14-21.
  58. Jacoby GA. Epidemiology of extended-spectrum beta-lactamases. Clin Infect Dis. 1998 Jul; 27(1):81-3.
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  59. Martínez-Martínez L, Pascual A, Jacoby GA. Quinolone resistance from a transferable plasmid. Lancet. 1998 Mar 14; 351(9105):797-9.
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  60. Jacoby GA. Extended-spectrum beta-lactamases and other enzymes providing resistance to oxyimino-beta-lactams. Infect Dis Clin North Am. 1997 Dec; 11(4):875-87.
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  61. Jacoby G, Han P, Tran J. Comparative in vitro activities of carbapenem L-749,345 and other antimicrobials against multiresistant gram-negative clinical pathogens. Antimicrob Agents Chemother. 1997 Aug; 41(8):1830-1.
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  62. Bush K, Jacoby G. Nomenclature of TEM beta-lactamases. J Antimicrob Chemother. 1997 Jan; 39(1):1-3.
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  63. Jacoby GA, Bush K. Amino acid sequences for TEM, SHV, and OXA extended-spectrum and inhibitor resistant beta-lactamases. 1997.
  64. Jacoby GA, Han P. Detection of extended-spectrum beta-lactamases in clinical isolates of Klebsiella pneumoniae and Escherichia coli. J Clin Microbiol. 1996 Apr; 34(4):908-11.
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  65. Martínez-Martínez L, Hernández-Allés S, Albertí S, Tomás JM, Benedi VJ, Jacoby GA. In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins. Antimicrob Agents Chemother. 1996 Feb; 40(2):342-8.
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  66. Jacoby GA. Antimicrobial-resistant pathogens in the 1990s. Annu Rev Med. 1996; 47:169-79.
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  67. Bush K, Jacoby GA, Medeiros AA. A functional classification scheme for beta-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother. 1995 Jun; 39(6):1211-33.
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  68. Jacoby GA. Urinary tract infection with Enterococcus faecalis. Ann Intern Med. 1995 Feb 1; 122(3):238.
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  69. Jacoby GA. Extrachromosomal resistance in gram-negative organisms: the evolution of beta-lactamase. Trends Microbiol. 1994 Oct; 2(10):357-60.
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  70. Jacoby GA. Prevalence and resistance mechanisms of common bacterial respiratory pathogens. Clin Infect Dis. 1994 Jun; 18(6):951-7.
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  71. Katsanis GP, Spargo J, Ferraro MJ, Sutton L, Jacoby GA. Detection of Klebsiella pneumoniae and Escherichia coli strains producing extended-spectrum beta-lactamases. J Clin Microbiol. 1994 Mar; 32(3):691-6.
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  72. Jacoby GA. Genetics of extended-spectrum beta-lactamases. Eur J Clin Microbiol Infect Dis. 1994; 13 Suppl 1:S2-11.
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  73. Rice LB, Marshall SH, Carias LL, Sutton L, Jacoby GA. Sequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes. Antimicrob Agents Chemother. 1993 Dec; 37(12):2760-1.
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  74. Arstila T, Jacoby GA, Huovinen P. Evaluation of five different methods to prepare bacterial extracts for the identification of beta-lactamases by isoelectric focusing. J Antimicrob Chemother. 1993 Dec; 32(6):809-16.
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  75. Jacoby GA. Infectious complications in bone marrow transplantation. Resistant bacterial infections. Recent Results Cancer Res. 1993; 132:241-7.
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  76. Katsanis G, Jacoby G. The frequency of extended-spectrum beta-lactamases in isolates of Klebsiella pneumoniae. J Antimicrob Chemother. 1992 Mar; 29(3):345-6.
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  77. Huovinen P, Jacoby GA. Sequence of the PSE-1 beta-lactamase gene. Antimicrob Agents Chemother. 1991 Nov; 35(11):2428-30.
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  78. Jacoby GA, Medeiros AA. More extended-spectrum beta-lactamases. Antimicrob Agents Chemother. 1991 Sep; 35(9):1697-704.
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  79. Jacoby GA, Archer GL. New mechanisms of bacterial resistance to antimicrobial agents. N Engl J Med. 1991 Feb 28; 324(9):601-12.
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  80. Rice LB, Eliopoulos GM, Wennersten C, Goldmann D, Jacoby GA, Moellering RC. Chromosomally mediated beta-lactamase production and gentamicin resistance in Enterococcus faecalis. Antimicrob Agents Chemother. 1991 Feb; 35(2):272-6.
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  81. Jacoby GA, Sutton L. Properties of plasmids responsible for production of extended-spectrum beta-lactamases. Antimicrob Agents Chemother. 1991 Jan; 35(1):164-9.
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  82. Jacoby GA, Blaser MJ, Santanam P, Hächler H, Kayser FH, Hare RS, Miller GH. Appearance of amikacin and tobramycin resistance due to 4'-aminoglycoside nucleotidyltransferase [ANT(4')-II] in gram-negative pathogens. Antimicrob Agents Chemother. 1990 Dec; 34(12):2381-6.
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  83. Rice LB, Willey SH, Papanicolaou GA, Medeiros AA, Eliopoulos GM, Moellering RC, Jacoby GA. Outbreak of ceftazidime resistance caused by extended-spectrum beta-lactamases at a Massachusetts chronic-care facility. Antimicrob Agents Chemother. 1990 Nov; 34(11):2193-9.
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  84. Papanicolaou GA, Medeiros AA, Jacoby GA. Novel plasmid-mediated beta-lactamase (MIR-1) conferring resistance to oxyimino- and alpha-methoxy beta-lactams in clinical isolates of Klebsiella pneumoniae. Antimicrob Agents Chemother. 1990 Nov; 34(11):2200-9.
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  85. Jacoby GA, Carreras I. Activities of beta-lactam antibiotics against Escherichia coli strains producing extended-spectrum beta-lactamases. Antimicrob Agents Chemother. 1990 May; 34(5):858-62.
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  86. Jacoby GA. Evolving beta-lactamases. Ayoub EM, Cassell GH, Branche WC Jr, Henry TJ, eds. Microbial determinants of virulence and host response. 1990; 361-76.
  87. Eliopoulos GM, Klimm K, Ferraro MJ, Jacoby GA, Moellering RC. Comparative in vitro activity of piperacillin combined with the beta-lactamase inhibitor tazobactam (YTR 830). Diagn Microbiol Infect Dis. 1989 Nov-Dec; 12(6):481-8.
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  88. Philippon A, Labia R, Jacoby G. Extended-spectrum beta-lactamases. Antimicrob Agents Chemother. 1989 Aug; 33(8):1131-6.
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  89. Jacoby GA, Sutton L. Pseudomonas cepacia susceptibility to sulbactam. Antimicrob Agents Chemother. 1989 Apr; 33(4):583-4.
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  90. Huovinen S, Huovinen P, Torniainen K, Jacoby GA. Evaluation of plasmid-encoded beta-lactamase resistance in Escherichia coli blood culture isolates. Eur J Clin Microbiol Infect Dis. 1988 Oct; 7(5):651-5.
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  91. Jacoby GA, Medeiros AA, O'Brien TF, Pinto ME, Jiang H. Broad-spectrum, transmissible beta-lactamases. N Engl J Med. 1988 Sep 15; 319(11):723-4.
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  92. Huovinen S, Huovinen P, Jacoby GA. Reliability of biotinylated DNA probes in colony hybridization: evaluation of an improved colony lysis method for detection of TEM-1 beta-lactamase. Mol Cell Probes. 1988 Mar; 2(1):83-5.
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  93. Huovinen S, Huovinén P, Jacoby GA. Detection of plasmid-mediated beta-lactamases with DNA probes. Antimicrob Agents Chemother. 1988 Feb; 32(2):175-9.
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  94. Levesque RC, Jacoby GA. Molecular structure and interrelationships of multiresistance beta-lactamase transposons. Plasmid. 1988 Jan; 19(1):21-9.
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  95. Huovinen P, Huovinen S, Jacoby GA. Sequence of PSE-2 beta-lactamase. Antimicrob Agents Chemother. 1988 Jan; 32(1):134-6.
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  96. Yang Y, Jacoby GA, Livermore DM. LXA-1: a new plasmid-mediated beta-lactamase giving low-level resistance. FEMS Microbiol Lett. 1988; 52:97-102.
  97. Levesque RC, Medeiros AA, Jacoby GA. Molecular cloning and DNA homology of plasmid-mediated beta-lactamase genes. Mol Gen Genet. 1987 Feb; 206(2):252-8.
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  98. Philippon AM, Paul GC, Jacoby GA. New plasmid-mediated oxacillin-hydrolyzing beta-lactamase in Pseudomonas aeruginosa. J Antimicrob Chemother. 1986 Apr; 17(4):415-22.
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  99. Philippon AM, Paul GC, Thabaut AP, Jacoby GA. Properties of a novel carbenicillin-hydrolyzing beta-lactamase (CARB-4) specified by an IncP-2 plasmid from Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1986 Mar; 29(3):519-20.
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  100. Medeiros AA, Levesque R, Jacoby GA. An animal source for the ROB-1 beta-lactamase of Haemophilus influenzae type b. Antimicrob Agents Chemother. 1986 Feb; 29(2):212-5.
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  101. Jacoby GA. Resistance plasmids of Pseudomonas. Sokatch JR,ed. The Bacteria. The biology of Pseudomonas. 1986; X:265-93.
  102. Medeiros AA, Jacoby GA. Beta-lactamase-mediated resistance. Queener SW, Queener SF, Webber JA, eds. Beta-lactam antibiotics for clinical use. 1986; 49-84.
  103. Jacoby GA. Babesiosis. Gellis SS, Kagan BM, eds. Current pediatric therapy 12. 1986; 606.
  104. Jacoby GA, Sutton L. beta-Lactamases and beta-lactam resistance in Escherichia coli. Antimicrob Agents Chemother. 1985 Nov; 28(5):703-5.
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  105. Medeiros AA, Cohenford M, Jacoby GA. Five novel plasmid-determined beta-lactamases. Antimicrob Agents Chemother. 1985 May; 27(5):715-9.
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  106. Hedges RW, Medeiros AA, Cohenford M, Jacoby GA. Genetic and biochemical properties of AER-1, a novel carbenicillin-hydrolyzing beta-lactamase from Aeromonas hydrophila. Antimicrob Agents Chemother. 1985 Apr; 27(4):479-84.
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  107. Jacoby GA. Genetics and epidemiology of resistance. Greenwood D, O'Grady F, eds. The scientific basis of antimicrobial chemotherapy. 1985; 185-218.
  108. Jacoby GA. Strategies for dealing with antibiotic resistance. Sande MA, Root RK, eds. New dimensions in antimicrobial therapy. 1984; 83-100.
  109. Jacoby GA. Resistance plasmids of Pseudomonas aeruginosa. Bryan, LE, ed. Antimicrobial drug resistance. 1984; 497-514.
  110. Philippon AM, Paul GC, Jacoby GA. Properties of PSE-2 beta-lactamase and genetic basis for its production in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1983 Sep; 24(3):362-9.
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  111. Jacoby GA, Sutton L, Knobel L, Mammen P. Properties of IncP-2 plasmids of Pseudomonas spp. Antimicrob Agents Chemother. 1983 Aug; 24(2):168-75.
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  112. Simpson IN, Plested SJ, Budin-Jones MJ, Lees J, Hedges RW, Jacoby GA. Characterization of a novel plasmid-mediated beta-lactamase and its contribution to beta-lactam resistance in Pseudomonas aeruginosa. FEMS Microbiol Lett. 1983; 19:23-7.
  113. Jacoby GA, Sutton L. Restriction-modification systems determined by Pseudomonas plasmids. Plasmid. 1982 Sep; 8(2):141-7.
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  114. Prince AS, Jacoby GA. Cloning the gentamicin resistance gene from a Pseudomonas aeruginosa plasmid in Escherichia coli enhances detection of aminoglycoside modification. Antimicrob Agents Chemother. 1982 Sep; 22(3):525-6.
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  115. Falkiner FR, Jacoby GA, Keane CT, McCann SR. Amikacin, gentamicin and tobramycin resistant Pseudomonas aeruginosa in a leukaemic ward. Epidemiology and genetic studies. J Hosp Infect. 1982 Sep; 3(3):253-61.
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  116. Richter JM, Jacoby GA, Schapiro H, Warshaw AL. Pancreatic abscess due to Candida albicans. Ann Intern Med. 1982 Aug; 97(2):221-2.
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  117. Calderwood SB, Gardella A, Philippon AM, Jacoby GA, Moellering RC. Effects of azlocillin in combination with clavulanic acid, sulbactam, and N-formimidoyl thienamycin against beta-lactamase-producing, carbenicillin-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1982 Aug; 22(2):266-71.
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  118. Medeiros AA, Hedges RW, Jacoby GA. Spread of a "Pseudomonas-specific" beta-lactamase to plasmids of enterobacteria. J Bacteriol. 1982 Feb; 149(2):700-7.
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  119. Jacoby GA. Perils of prophylaxis. N Engl J Med. 1982 Jan 7; 306(1):43-4.
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  120. Jacoby GA, Hunt JV, Kosinski KS, Demirjian ZN, Huggins C, Etkind P, Marcus LC, Spielman A. Treatment of transfusion-transmitted babesiosis by exchange transfusion. N Engl J Med. 1980 Nov 6; 303(19):1098-100.
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  121. Jacoby GA, Swartz MN. Plasmids: microbiological and clinical importance. Weinstein L, Fields BN, eds. Seminars in infectious disease. 1980; 3:1-37.
  122. Summers AO, Weiss RB, Jacoby GA. Transposition of mercury resistance from a transferable R plasmic of Escherichia coli. Plasmid. 1980 Jan; 3(1):35-47.
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  123. Jacoby GA. Plasmid determined resistance to carbenicillin and gentamicin in Pseudomonas aeruginosa. Stuttard C, Rozee KR, eds. Plasmids and transposons: environmental effects and maintenance mechanisms. New York: Academic Press. 1980; 83-96.
  124. Jacoby GA, Sutton L, Medeiros AA. Plasmid-determined beta-lactamases of Pseudomonas aeruginosa. Nelson JD, Grassi C, eds. Current Chemotherapy and infectious disease. Washington DC: American Society for Microbiology. 1980; 769-71.
  125. Hedges RW, Jacoby GA. Compatibility and molecular properties of plasmid Rms 149 in Pseudomonas aeruginosa and Escherichia coli. Plasmid. 1980 Jan; 3(1):1-6.
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  126. Jacoby GA, Low KB. Genetics of antimicrobial resistance. The effects on human health of subtherapeutic use of antimicrobials in animal feeds. 1980; 92-129.
  127. Jacoby GA, Sutton L. Activity of beta-lactam antibiotics against Pseudomonas aeruginosa carrying R plasmids determining different beta-lactamases. Antimicrob Agents Chemother. 1979 Aug; 16(2):243-5.
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  128. Jacoby GA. Plasmids of Pseudomonas aeruginosa. Doggett RD, ed. Pseudomonas aeruginosa: clinical manifestations of infection and current therapy. 1979; 271-309.
  129. Jacoby GA, Matthew M. The distribution of beta-lactamase genes on plasmids found in Pseudomonas. Plasmid. 1979 Jan; 2(1):41-7.
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  130. Jacoby GA, Weiss R, Korfhagen TR, Krishnapillai V, Jacob AE, Hedges RW. An explanation for the apparent host specificity of Pseudomonas plasmid R91 expression. J Bacteriol. 1978 Dec; 136(3):1159-64.
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  131. Jacoby GA, Rogers JE, Jacob AE, Hedges RW. Transposition of Pseudomonas toluene-degrading genes and expression in Escherichia coli. Nature. 1978 Jul 13; 274(5667):179-80.
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  132. Sutton L, Jacoby GA. Plasmid-determined resistance to hexachlorophene in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1978 Apr; 13(4):634-6.
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  133. Summers AO, Jacoby GA. Plasmid-determined resistance to boron and chromium compounds in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1978 Apr; 13(4):637-40.
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  134. Korfhagen TR, Sutton L, Jacoby GA. Classification and physical properties of Pseudomonas plasmids. Schlessinger D, ed. Microbiology-1978. Washington, DC: American Socieity for Microbiology. 1978; 221-4.
  135. Summers AO, Jacoby GA, Swartz MN, McHugh G, Sutton L. Metal cation and oxyanion resistance in plasmids of gram-negative bacteria. Schlessinger D, ed. Microbiology-1978. Washington DC: American Society for Microbiology. 1978; 128-31.
  136. Jacoby GA, Sutton L. Restriction and modification determined by a Pseudomonas R plasmid. Plasmid. 1977 Nov; 1(1):115-6.
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  137. Falkiner FR, Keane CT, Dalton M, Clancy MT, Jacoby GA. Cross infection in a surgical ward caused by Pseudomonas aeruginosa with transferable resistance to gentamicin and tobramycin. J Clin Pathol. 1977 Aug; 30(8):731-7.
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  138. Jacoby GA. Classification of plasmids in Pseudomonas aeruginosa. Schlessinger D, ed. Microbiology-1977. Washington DC: American Society for Microbiology. 1977; 119-26.
  139. Jacoby GA, Shapiro JA. Plasmids studied in Pseudomonas aeruginosa and other pseudomonads. Bukhari AI, Shapiro J, Adhya S, eds. DNA insertion elements, plasmids, and episomes. 1977.
  140. Summers AO, Jacoby GA. Plasmid-determined resistance to tellurium compounds. J Bacteriol. 1977 Jan; 129(1):276-81.
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  141. Lehrbach P, Kung AH, Lee BT, Jacoby GA. Plasmid modification of radiation and chemical-mutagen sensitivity in Pseudomonas aeruginosa. J Gen Microbiol. 1977 Jan; 98(1):167-76.
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  142. Jacoby GA, Jacob AE. Recombination between Pseudomonas aeruginosa plasmids of incompatibility groups P-1 and P-2. Bukhari AI, Shapiro J, Adhya S, eds. DNA insertion eleements, plasmids, and episomes. Cold Spring Harbor: Cold Spring Harbor Laboratories. 1977; 147-50.
  143. Jacoby GA, Jacob AE, Hedges RW. Recombination between plasmids of incompatibility groups P-1 and P-2. J Bacteriol. 1976 Sep; 127(3):1278-85.
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  144. Jacoby GA. R plasmids determining gentamicin or tobramycin resistance in Pseudomonas aeruginosa. Mitsuhashi S, Rosival L, Krcmery V, eds. Drug-inactivating enzymes and antibiotic resistance. Berlin: Springer-Verlag. 1975; 287-95.
  145. Jacoby GA. Propertries of R plasmids in Pseudomonas aeruginosa. Schlessinger D., ed. Microbiology-1974. Washington DC: American Society for Microbiology. 1975; 36-42.
  146. Jacoby GA. Properties of an R plasmid in Pseudomonas aeruginosa producing amikacin (BB-K8), butirosin, kanamycin, tobramycin, and sisomicin resistance. Antimicrob Agents Chemother. 1974 Dec; 6(6):807-10.
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  147. Jacoby GA. Properties of R plasmids determining gentamicin resistance by acetylation in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1974 Sep; 6(3):239-52.
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  148. Jacoby GA, Swartz MN. Psittacosis. Conn HF, Conn RB Jr, eds. Current diagnosis 4. 1974; 110-11.
  149. Jacoby GA, Swartz MN. Fever of undetermined origin. N Engl J Med. 1973 Dec 27; 289(26):1407-10.
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  150. Jacoby GA. An R factor defects to our side. N Engl J Med. 1972 Mar 16; 286(11):602-3.
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  151. Jacoby GA. Control of the argECBH cluster in Escherichia coli. Mol Gen Genet. 1972; 117(4):337-48.
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  152. Jacoby GA. Mapping the gene determining ornithine transcarbamylase and its operator in Escherichia coli B. J Bacteriol. 1971 Nov; 108(2):645-51.
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  153. Jacoby GA. Carbenicillin and gentamicin. N Engl J Med. 1971 May 13; 284(19):1096-8.
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  154. Jacoby GA, Gorini L. A unitary account of the repression mechanism of arginine biosynthesis in Escherichia coli. I. The genetic evidence. J Mol Biol. 1969 Jan 14; 39(1):73-87.
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  155. Jacoby GA, Gorini L. The effect of streptomycin and other aminoglycoside antibiotics on protein synthesis. Gottlieb D, Shaw PD, eds. Antibiotics I, Mechanism of action. 1967; 726-47.
  156. Gorini L, Jacoby GA, Breckenridge L. Ribosomal ambiguity. Cold Spring Harb Symp Quant Biol. 1966; 31:657-64.
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  157. HABER E, PAGE LB, JACOBY GA. SYNTHESIS OF ANTIGENIC BRANCH-CHAIN COPOLYMERS OF ANGIOTENSIN AND POLY-L-LYSINE. Biochemistry. 1965 Apr; 4:693-8.
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  158. MANDELSTAM J, JACOBY GA. INDUCTION AND MULTI-SENSITIVE END-PRODUCT REPRESSION IN THE ENZYMIC PATHWAY DEGRADING MANDELATE IN PSEUDOMONAS FLUORESCENS. Biochem J. 1965 Mar; 94:569-77.
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  159. Jacoby GA. The induction and repression of amino acid oxidation in Pseudomonas fluorescens. Biochem J. 1964 Jul; 92(1):1-8.
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  160. PAGE LB, JACOBY GA. CATECHOL AMINE METABOLISM AND STORAGE GRANULES IN PHEOCHROMOCYTOMA AND NEUROBLASTOMA. Medicine (Baltimore). 1964 May; 43:379-86.
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  161. JACOBY GA, LADU BN. STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE. J Biol Chem. 1964 Feb; 239:419-24.
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  162. LADU BN, HOWELL RR, JACOBY GA, SEEGMILLER JE, SOBER EK, ZANNONI VG, CANBY JP, ZIEGLER LK. CLINICAL AND BIOCHEMICAL STUDIES ON TWO CASES OF HISTIDINEMIA. Pediatrics. 1963 Aug; 32:216-27.
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  163. ZANNONI VG, JACOBY GA, MALAWISTA SE, LA DU BN. The effect of folic acid on tyrosine metabolism in guinea pigs. J Biol Chem. 1962 Nov; 237:3506-9.
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  164. JACOBY GA, LA DU BN. Nonspecificity of tyrosine transaminase: an explanation for the simultaneous induction of tyrosine, phenylalanine, and tryptophan transaminase activities in rat liver. Biochem Biophys Res Commun. 1962 Aug 7; 8:352-6.
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  165. LA DU BN, HOWELL RR, JACOBY GA, SEEGMILLER JE, ZANNONI VG. The enzymatic defect in histidinemia. Biochem Biophys Res Commun. 1962 May 11; 7:398-402.
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  166. ZANNONI VG, JACOBY GA, LA DU BN. The effect of coenzyme Q-10 on tyrosine metabolism in guinea pigs. Biochem Biophys Res Commun. 1962 Apr 20; 7:220-4.
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