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J. Thomas Lamont, M.D.

TitleCharlotte F. and Irving W. Rabb Professor of Medicine
InstitutionBeth Israel Deaconess Medical Center
DepartmentMedicine
AddressBeth Israel Deaconess Med Ctr
Chief, Gastroenterology
330 Brookline Ave
Boston MA 02215
Phone617/667-8377
Fax617/667-2767

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Leffler DA, Kheraj R, Bhansali A, Yamanaka H, Neeman N, Sheth S, Sawhney M, Lamont JT, Aronson MD. Adenoma detection rates vary minimally with time of day and case rank: a prospective study of 2139 first screening colonoscopies. Gastrointest Endosc. 2012 Mar; 75(3):554-60.
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  2. Leffler DA, Lamont JT. Editorial: not so nosocomial anymore: the growing threat of community-acquired Clostridium difficile. Am J Gastroenterol. 2012 Jan; 107(1):96-8.
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  3. Kang JK, Hwang JS, Nam HJ, Ahn KJ, Seok H, Kim SK, Yun EY, Pothoulakis C, Lamont JT, Kim H. The insect peptide coprisin prevents Clostridium difficile-mediated acute inflammation and mucosal damage through selective antimicrobial activity. Antimicrob Agents Chemother. 2011 Oct; 55(10):4850-7.
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  4. Berzin TM, Blanco PG, Lamont JT, Sawhney MS. Persistent psychological or physical symptoms following endoscopic procedures: an unrecognized post-endoscopy adverse event. Dig Dis Sci. 2010 Oct; 55(10):2869-73.
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  5. Nam HJ, Kang JK, Kim SK, Ahn KJ, Seok H, Park SJ, Chang JS, Pothoulakis C, Lamont JT, Kim H. Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation. J Biol Chem. 2010 Oct 22; 285(43):32888-96.
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  6. Jangi S, Lamont JT. Asymptomatic colonization by Clostridium difficile in infants: implications for disease in later life. J Pediatr Gastroenterol Nutr. 2010 Jul; 51(1):2-7.
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  7. Leffler DA, Lamont JT. A 69-year-old woman presenting to the hospital with 48 hours of abdominal pain and diarrhea. Clin Gastroenterol Hepatol. 2009 Oct; 7(10):1046-8.
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  8. Kim H, Rhee SH, Pothoulakis C, LaMont JT. Clostridium difficile toxin A binds colonocyte Src causing dephosphorylation of focal adhesion kinase and paxillin. Exp Cell Res. 2009 Nov 15; 315(19):3336-44.
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  9. Leffler DA, Lamont JT. Treatment of Clostridium difficile-associated disease. Gastroenterology. 2009 May; 136(6):1899-912.
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  10. Kelly CP, LaMont JT. Clostridium difficile--more difficult than ever. N Engl J Med. 2008 Oct 30; 359(18):1932-40.
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  11. Na X, Kim H, Moyer MP, Pothoulakis C, LaMont JT. gp96 is a human colonocyte plasma membrane binding protein for Clostridium difficile toxin A. Infect Immun. 2008 Jul; 76(7):2862-71.
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  12. Kim H, Rhee SH, Pothoulakis C, Lamont JT. Inflammation and apoptosis in Clostridium difficile enteritis is mediated by PGE2 up-regulation of Fas ligand. Gastroenterology. 2007 Sep; 133(3):875-86.
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  13. Maroo S, Lamont JT. Recurrent clostridium difficile. Gastroenterology. 2006 Apr; 130(4):1311-6.
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  14. Kim H, Kokkotou E, Na X, Rhee SH, Moyer MP, Pothoulakis C, Lamont JT. Clostridium difficile toxin A-induced colonocyte apoptosis involves p53-dependent p21(WAF1/CIP1) induction via p38 mitogen-activated protein kinase. Gastroenterology. 2005 Dec; 129(6):1875-88.
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  15. Na X, Zhao D, Koon HW, Kim H, Husmark J, Moyer MP, Pothoulakis C, LaMont JT. Clostridium difficile toxin B activates the EGF receptor and the ERK/MAP kinase pathway in human colonocytes. Gastroenterology. 2005 Apr; 128(4):1002-11.
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  16. Kim H, Rhee SH, Kokkotou E, Na X, Savidge T, Moyer MP, Pothoulakis C, LaMont JT. Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK. J Biol Chem. 2005 Jun 3; 280(22):21237-45.
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  17. Morrin MM, LaMont JT. Screening virtual colonoscopy--ready for prime time? N Engl J Med. 2003 Dec 4; 349(23):2261-4.
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  18. Espenschied J, Lamont J, Longmate J, Pendas S, Wang Z, Diamond DJ, Ellenhorn JD. CTLA-4 blockade enhances the therapeutic effect of an attenuated poxvirus vaccine targeting p53 in an established murine tumor model. J Immunol. 2003 Mar 15; 170(6):3401-7.
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  19. Li Y, Sun X, LaMont JT, Pardee AB, Li CJ. Selective killing of cancer cells by beta -lapachone: direct checkpoint activation as a strategy against cancer. Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5):2674-8.
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  20. Khatri IA, Bhaskar KR, Lamont JT, Sajjan SU, Ho CK, Forstner J. Effect of chondroitinase ABC on purulent sputum from cystic fibrosis and other patients. Pediatr Res. 2003 Apr; 53(4):619-27.
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  21. Liu TS, Musch MW, Sugi K, Walsh-Reitz MM, Ropeleski MJ, Hendrickson BA, Pothoulakis C, Lamont JT, Chang EB. Protective role of HSP72 against Clostridium difficile toxin A-induced intestinal epithelial cell dysfunction. Am J Physiol Cell Physiol. 2003 Apr; 284(4):C1073-82.
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  22. He D, Sougioultzis S, Hagen S, Liu J, Keates S, Keates AC, Pothoulakis C, Lamont JT. Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation. Gastroenterology. 2002 Apr; 122(4):1048-57.
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  23. Farrell RJ, LaMont JT. Microbial factors in inflammatory bowel disease. Gastroenterol Clin North Am. 2002 Mar; 31(1):41-62.
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  24. Agarwal B, Halmos B, Feoktistov AS, Protiva P, Ramey WG, Chen M, Pothoulakis C, Lamont JT, Holt PR. Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells. Carcinogenesis. 2002 Mar; 23(3):521-8.
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  25. Lamont JT. Theodore E. Woodward Award. How bacterial enterotoxins work: insights from in vivo studies. Trans Am Clin Climatol Assoc. 2002; 113:167-80; discussion 180-1.
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  26. Chen ML, Pothoulakis C, LaMont JT. Protein kinase C signaling regulates ZO-1 translocation and increased paracellular flux of T84 colonocytes exposed to Clostridium difficile toxin A. J Biol Chem. 2002 Feb 8; 277(6):4247-54.
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  27. Qamar A, Aboudola S, Warny M, Michetti P, Pothoulakis C, LaMont JT, Kelly CP. Saccharomyces boulardii stimulates intestinal immunoglobulin A immune response to Clostridium difficile toxin A in mice. Infect Immun. 2001 Apr; 69(4):2762-5.
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  28. Sheth SG, LaMont JT. Gastrointestinal problems in the chronically critically ill patient. Clin Chest Med. 2001 Mar; 22(1):135-47.
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  29. Pothoulakis C, Lamont JT. Microbes and microbial toxins: paradigms for microbial-mucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins. Am J Physiol Gastrointest Liver Physiol. 2001 Feb; 280(2):G178-83.
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  30. LaMONT JT. Unlocking the secrets of the porcelain vase. Gastroenterology. 2000 Nov; 119(5):1397-9.
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  31. Farrell RJ, Alsahli M, LaMont JT. Is successful triage of patients with upper-gastrointestinal bleeding possible without endoscopy? Lancet. 2000 Oct 14; 356(9238):1289-90.
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  32. LaMont JT. The renaissance of probiotics and prebiotics. Gastroenterology. 2000 Aug; 119(2):291.
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  33. He D, Hagen SJ, Pothoulakis C, Chen M, Medina ND, Warny M, LaMont JT. Clostridium difficile toxin A causes early damage to mitochondria in cultured cells. Gastroenterology. 2000 Jul; 119(1):139-50.
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  34. Banerjee S, Lamont JT. Non-antibiotic therapy for Clostridium difficile infection. Curr Opin Infect Dis. 2000 Jun; 13(3):215-219.
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  35. Warny M, Keates AC, Keates S, Castagliuolo I, Zacks JK, Aboudola S, Qamar A, Pothoulakis C, LaMont JT, Kelly CP. p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis. J Clin Invest. 2000 Apr; 105(8):1147-56.
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  36. Banerjee S, LaMont JT. Treatment of gastrointestinal infections. Gastroenterology. 2000 Feb; 118(2 Suppl 1):S48-67.
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  37. Farrell RJ, LaMont JT. Pathogenesis and clinical manifestations of Clostridium difficile diarrhea and colitis. Curr Top Microbiol Immunol. 2000; 250:109-25.
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  38. Castagliuolo I, LaMont JT. Pathophysiology, diagnosis and treatment of Clostridium difficile infection. Keio J Med. 1999 Dec; 48(4):169-74.
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  39. Turner BS, Bhaskar KR, Hadzopoulou-Cladaras M, LaMont JT. Cysteine-rich regions of pig gastric mucin contain von willebrand factor and cystine knot domains at the carboxyl terminal(1). Biochim Biophys Acta. 1999 Oct 6; 1447(1):77-92.
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  40. Morrin MM, Farrell RJ, Kruskal JB, LaMont JT. Virtual colonoscopy: a kinder, gentler colorectal cancer screening test? Lancet. 1999 Sep 25; 354(9184):1048-9.
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  41. LaMont JT. Endangered species. Gastroenterology. 1999 Jul; 117(1):5.
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  42. Riegler M, Lotz M, Sears C, Pothoulakis C, Castagliuolo I, Wang CC, Sedivy R, Sogukoglu T, Cosentini E, Bischof G, Feil W, Teleky B, Hamilton G, LaMont JT, Wenzl E. Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro. Gut. 1999 Apr; 44(4):504-10.
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  43. Cao X, Bansil R, Bhaskar KR, Turner BS, LaMont JT, Niu N, Afdhal NH. pH-dependent conformational change of gastric mucin leads to sol-gel transition. Biophys J. 1999 Mar; 76(3):1250-8.
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  44. Qiu B, Pothoulakis C, Castagliuolo I, Nikulasson S, LaMont JT. Participation of reactive oxygen metabolites in Clostridium difficile toxin A-induced enteritis in rats. Am J Physiol. 1999 Feb; 276(2 Pt 1):G485-90.
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  45. Warny M, Fatimi A, Bostwick EF, Laine DC, Lebel F, LaMont JT, Pothoulakis C, Kelly CP. Bovine immunoglobulin concentrate-clostridium difficile retains C difficile toxin neutralising activity after passage through the human stomach and small intestine. Gut. 1999 Feb; 44(2):212-7.
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  46. Castagliuolo I, Riegler MF, Valenick L, LaMont JT, Pothoulakis C. Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa. Infect Immun. 1999 Jan; 67(1):302-7.
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  47. Farrell RJ, LaMont JT. Rational approach to iron-deficiency anaemia in premenopausal women. Lancet. 1998 Dec 19-26; 352(9145):1953-4.
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  48. Castagliuolo I, Keates AC, Wang CC, Pasha A, Valenick L, Kelly CP, Nikulasson ST, LaMont JT, Pothoulakis C. Clostridium difficile toxin A stimulates macrophage-inflammatory protein-2 production in rat intestinal epithelial cells. J Immunol. 1998 Jun 15; 160(12):6039-45.
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  49. Sheth SG, LaMont JT. Toxic megacolon. Lancet. 1998 Feb 14; 351(9101):509-13.
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  50. Pothoulakis C, Castagliuolo I, LaMont JT. Nerves and Intestinal Mast Cells Modulate Responses to Enterotoxins. News Physiol Sci. 1998 Apr; 13:58-63.
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  51. Kelly CP, LaMont JT. Clostridium difficile infection. Annu Rev Med. 1998; 49:375-90.
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  52. Bhaskar KR, Turner BS, Grubman SA, Jefferson DM, LaMont JT. Dysregulation of proteoglycan production by intrahepatic biliary epithelial cells bearing defective (delta-f508) cystic fibrosis transmembrane conductance regulator. Hepatology. 1998 Jan; 27(1):7-14.
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  53. Linevsky JK, Pothoulakis C, Keates S, Warny M, Keates AC, Lamont JT, Kelly CP. IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes. Am J Physiol. 1997 Dec; 273(6 Pt 1):G1333-40.
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  54. Riegler M, Sedivy R, Sogukoglu T, Castagliuolo I, Pothoulakis C, Cosentini E, Bischof G, Hamilton G, Teleky B, Feil W, Lamont JT, Wenzl E. Epidermal growth factor attenuates Clostridium difficile toxin A- and B-induced damage of human colonic mucosa. Am J Physiol. 1997 Nov; 273(5 Pt 1):G1014-22.
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  55. Salcedo J, Keates S, Pothoulakis C, Warny M, Castagliuolo I, LaMont JT, Kelly CP. Intravenous immunoglobulin therapy for severe Clostridium difficile colitis. Gut. 1997 Sep; 41(3):366-70.
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  56. Castagliuolo I, Kelly CP, Qiu BS, Nikulasson ST, LaMont JT, Pothoulakis C. IL-11 inhibits Clostridium difficile toxin A enterotoxicity in rat ileum. Am J Physiol. 1997 Aug; 273(2 Pt 1):G333-41.
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  57. Marshall AT, LaMont JT. Cryptosporidiosis and public health. Hosp Pract (Minneap). 1997 Jul 15; 32(7):11, 15-6, 23.
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  58. Bousvaros A, Stevens AC, Strom TB, Murphy J, Lamont JT. Interleukin-2 fusion protein (DAB389IL-2) selectively targets activated human peripheral blood and lamina propria lymphocytes. Dig Dis Sci. 1997 Jul; 42(7):1542-8.
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  59. Podolsky DK, LaMont JT. Learning from the mistakes of Malthus: GI and manpower planning. Gastroenterology. 1997 Feb; 112(2):325.
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  60. Grübel P, Bhaskar KR, Cave DR, Garik P, Stanley HE, Lamont JT. Interaction of an aluminum-magnesium containing antacid and gastric mucus: possible contribution to the cytoprotective function of antacids. Aliment Pharmacol Ther. 1997 Feb; 11(1):139-45.
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  61. Kelly CP, Chetham S, Keates S, Bostwick EF, Roush AM, Castagliuolo I, LaMont JT, Pothoulakis C. Survival of anti-Clostridium difficile bovine immunoglobulin concentrate in the human gastrointestinal tract. Antimicrob Agents Chemother. 1997 Feb; 41(2):236-41.
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  62. Castagliuolo I, LaMont JT, Nikulasson ST, Pothoulakis C. Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum. Infect Immun. 1996 Dec; 64(12):5225-32.
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  63. Castagliuolo I, Lamont JT, Qiu B, Fleming SM, Bhaskar KR, Nikulasson ST, Kornetsky C, Pothoulakis C. Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells. Am J Physiol. 1996 Nov; 271(5 Pt 1):G884-92.
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  64. Castagliuolo I, LaMont JT, Qiu B, Nikulasson ST, Pothoulakis C. A receptor decoy inhibits the enterotoxic effects of Clostridium difficile toxin A in rat ileum. Gastroenterology. 1996 Aug; 111(2):433-8.
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  65. Pothoulakis C, Gilbert RJ, Cladaras C, Castagliuolo I, Semenza G, Hitti Y, Montcrief JS, Linevsky J, Kelly CP, Nikulasson S, Desai HP, Wilkins TD, LaMont JT. Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A. J Clin Invest. 1996 Aug 1; 98(3):641-9.
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  66. Qiu B, Pothoulakis C, Castagliuolo I, Nikulasson Z, LaMont JT. Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin. Gastroenterology. 1996 Aug; 111(2):409-18.
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  67. Larson RG, Turner BS, Bhaskar KR, LaMont JT, Rothschild MF. Rapid communication: BamHI restriction fragment length polymorphism detected with a pig gastric mucin (MUC5AC) probe. J Anim Sci. 1996 Jun; 74(6):1443.
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  68. Pothoulakis C, Galili U, Castagliuolo I, Kelly CP, Nikulasson S, Dudeja PK, Brasitus TA, LaMont JT. A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon. Gastroenterology. 1996 Jun; 110(6):1704-12.
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  69. LaRusso NF, Phillips SF, Bloomer JR, Boland CR, Chang EB, DiMagno EP, Giannella RA, Gores GJ, Malagelada JR, Miller LJ, Rakela J, Szurszewski JH, Binder HJ, Clain JE, LaMont JT, Link AM. Passing the torch: a look back at our editorship. Gastroenterology. 1996 May; 110(5):1336-8.
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  70. Kelly CP, Pothoulakis C, Vavva F, Castagliuolo I, Bostwick EF, O'Keane JC, Keates S, LaMont JT. Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins. Antimicrob Agents Chemother. 1996 Feb; 40(2):373-9.
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  71. Dunzendorfer T, LaMont JT. Recurrent pseudo-Crohn's disease. Dig Dis Sci. 1995 Sep; 40(9):1922-4.
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  72. Turner BS, Bhaskar KR, Hadzopoulou-Cladaras M, Specian RD, LaMont JT. Isolation and characterization of cDNA clones encoding pig gastric mucin. Biochem J. 1995 May 15; 308 ( Pt 1):89-96.
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  73. Riegler M, Sedivy R, Pothoulakis C, Hamilton G, Zacherl J, Bischof G, Cosentini E, Feil W, Schiessel R, LaMont JT, et al. Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro. J Clin Invest. 1995 May; 95(5):2004-11.
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  74. Dillon ST, Rubin EJ, Yakubovich M, Pothoulakis C, LaMont JT, Feig LA, Gilbert RJ. Involvement of Ras-related Rho proteins in the mechanisms of action of Clostridium difficile toxin A and toxin B. Infect Immun. 1995 Apr; 63(4):1421-6.
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  75. Gilbert RJ, Pothoulakis C, LaMont JT, Yakubovich M. Clostridium difficile toxin B activates calcium influx required for actin disassembly during cytotoxicity. Am J Physiol. 1995 Mar; 268(3 Pt 1):G487-95.
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  76. Bansil R, Stanley E, LaMont JT. Mucin biophysics. Annu Rev Physiol. 1995; 57:635-57.
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  77. Kurose I, Pothoulakis C, LaMont JT, Anderson DC, Paulson JC, Miyasaka M, Wolf R, Granger DN. Clostridium difficile toxin A-induced microvascular dysfunction. Role of histamine. J Clin Invest. 1994 Nov; 94(5):1919-26.
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  78. Castagliuolo I, LaMont JT, Letourneau R, Kelly C, O'Keane JC, Jaffer A, Theoharides TC, Pothoulakis C. Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum. Gastroenterology. 1994 Sep; 107(3):657-65.
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  79. Mitty RD, Lamont JT. Clostridium difficile colitis: epidemiology, pathophysiology, and treatment. Mt Sinai J Med. 1994 Sep; 61(4):329-35.
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  80. Kelly CP, Becker S, Linevsky JK, Joshi MA, O'Keane JC, Dickey BF, LaMont JT, Pothoulakis C. Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit. J Clin Invest. 1994 Mar; 93(3):1257-65.
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  81. Mitty RD, LaMont JT. Clostridium difficile diarrhea: pathogenesis, epidemiology, and treatment. Gastroenterologist. 1994 Mar; 2(1):61-9.
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  82. LaMont JT. Why fibre is good for you. Lancet. 1994 Feb 12; 343(8894):372.
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  83. Pothoulakis C, Castagliuolo I, LaMont JT, Jaffer A, O'Keane JC, Snider RM, Leeman SE. CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc Natl Acad Sci U S A. 1994 Feb 1; 91(3):947-51.
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  84. Kelly CP, Pothoulakis C, LaMont JT. Clostridium difficile colitis. N Engl J Med. 1994 Jan 27; 330(4):257-62.
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  85. Pothoulakis C, LaMont JT. Clostridium difficile colitis and diarrhea. Gastroenterol Clin North Am. 1993 Sep; 22(3):623-37.
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  86. Pothoulakis C, Karmeli F, Kelly CP, Eliakim R, Joshi MA, O'Keane CJ, Castagliuolo I, LaMont JT, Rachmilewitz D. Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum. Gastroenterology. 1993 Sep; 105(3):701-7.
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  87. Pothoulakis C, Castagliuolo I, Kelly CP, Lamont JT. Clostridium difficile-associated diarrhea and colitis: pathogenesis and therapy. Int J Antimicrob Agents. 1993 Jul; 3(1):17-32.
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  88. Pothoulakis C, Castagliuolo I, LaMont JT. Diagnostic tests for Clostridium difficile diarrhoea and colitis: past, present and future. J Gastroenterol Hepatol. 1993 Jul-Aug; 8(4):311-2.
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  89. Pothoulakis C, Kelly CP, Joshi MA, Gao N, O'Keane CJ, Castagliuolo I, Lamont JT. Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum. Gastroenterology. 1993 Apr; 104(4):1108-15.
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  90. Afdhal NH, Gong D, Niu N, Turner B, LaMont JT, Offner GD. Cholesterol cholelithiasis in the prairie dog: role of mucin and nonmucin glycoproteins. Hepatology. 1993 Apr; 17(4):693-700.
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  91. Beubler E, Schirgi-Degen A, Pabst MA, Pothoulakis C, LaMont JT. Effects of purified Clostridium difficile toxin A in the small intestine of the rat in vivo. Nat Toxins. 1993; 1(6):369-75.
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  92. Bhaskar KR, Garik P, Turner BS, Bradley JD, Bansil R, Stanley HE, LaMont JT. Viscous fingering of HCl through gastric mucin. Nature. 1992 Dec 3; 360(6403):458-61.
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  93. Kelly CP, O'Keane JC, Orellana J, Schroy PC, Yang S, LaMont JT, Brady HR. Human colon cancer cells express ICAM-1 in vivo and support LFA-1-dependent lymphocyte adhesion in vitro. Am J Physiol. 1992 Dec; 263(6 Pt 1):G864-70.
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  94. Eglow R, Pothoulakis C, Itzkowitz S, Israel EJ, O'Keane CJ, Gong D, Gao N, Xu YL, Walker WA, LaMont JT. Diminished Clostridium difficile toxin A sensitivity in newborn rabbit ileum is associated with decreased toxin A receptor. J Clin Invest. 1992 Sep; 90(3):822-9.
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  95. Hecht G, Koutsouris A, Pothoulakis C, LaMont JT, Madara JL. Clostridium difficile toxin B disrupts the barrier function of T84 monolayers. Gastroenterology. 1992 Feb; 102(2):416-23.
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  96. Lamont JT, Carey MC. Cholesterol gallstone formation. 2. Pathobiology and pathomechanics. Prog Liver Dis. 1992; 10:165-91.
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  97. Kelly CP, Pothoulakis C, Orellana J, LaMont JT. Human colonic aspirates containing immunoglobulin A antibody to Clostridium difficile toxin A inhibit toxin A-receptor binding. Gastroenterology. 1992 Jan; 102(1):35-40.
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  98. Carey MC, Lamont JT. Cholesterol gallstone formation. 1. Physical-chemistry of bile and biliary lipid secretion. Prog Liver Dis. 1992; 10:139-63.
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  99. Lamont JT. Mucus: the front line of intestinal mucosal defense. Ann N Y Acad Sci. 1992; 664:190-201.
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  100. Bhaskar KR, Gong DH, Bansil R, Pajevic S, Hamilton JA, Turner BS, LaMont JT. Profound increase in viscosity and aggregation of pig gastric mucin at low pH. Am J Physiol. 1991 Nov; 261(5 Pt 1):G827-32.
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  101. Pothoulakis C, LaMont JT, Eglow R, Gao N, Rubins JB, Theoharides TC, Dickey BF. Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein. J Clin Invest. 1991 Jul; 88(1):119-25.
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  102. O'Leary DP, Murray FE, Turner BS, LaMont JT. Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro. Hepatology. 1991 May; 13(5):957-61.
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  103. Zeisel SH, Da Costa KA, Franklin PD, Alexander EA, Lamont JT, Sheard NF, Beiser A. Choline, an essential nutrient for humans. FASEB J. 1991 Apr; 5(7):2093-8.
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  104. Leung DY, Kelly CP, Boguniewicz M, Pothoulakis C, LaMont JT, Flores A. Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin. J Pediatr. 1991 Apr; 118(4 Pt 1):633-7.
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  105. Gong DH, Turner B, Bhaskar KR, Lamont JT. Lipid binding to gastric mucin: protective effect against oxygen radicals. Am J Physiol. 1990 Oct; 259(4 Pt 1):G681-6.
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  106. Moore R, Pothoulakis C, LaMont JT, Carlson S, Madara JL. C. difficile toxin A increases intestinal permeability and induces Cl- secretion. Am J Physiol. 1990 Aug; 259(2 Pt 1):G165-72.
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  107. Miller PD, Pothoulakis C, Baeker TR, LaMont JT, Rothstein TL. Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore. Cell Immunol. 1990 Mar; 126(1):155-63.
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  108. Triadafilopoulos G, Pothoulakis C, Weiss R, Giampaolo C, Lamont JT. Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum. Gastroenterology. 1989 Nov; 97(5):1186-92.
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  109. Smith BF, Peetermans JA, Tanaka T, LaMont JT. Subunit interactions and physical properties of bovine gallbladder mucin. Gastroenterology. 1989 Jul; 97(1):179-87.
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  110. Gilbert RJ, Pothoulakis C, LaMont JT. Effect of purified Clostridium difficile toxins on intestinal smooth muscle. II. Toxin B. Am J Physiol. 1989 Apr; 256(4 Pt 1):G767-72.
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  111. Gilbert RJ, Triadafilopoulos G, Pothoulakis C, Giampaolo C, LaMont JT. Effect of purified Clostridium difficile toxins on intestinal smooth muscle. I. Toxin A. Am J Physiol. 1989 Apr; 256(4 Pt 1):G759-66.
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  112. LaMont JT. Oxygen radicals stimulate gallbladder glycoprotein secretion. Symp Soc Exp Biol. 1989; 43:273-8.
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  113. Hecht G, Pothoulakis C, LaMont JT, Madara JL. Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers. J Clin Invest. 1988 Nov; 82(5):1516-24.
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  114. Pothoulakis C, Sullivan R, Melnick DA, Triadafilopoulos G, Gadenne AS, Meshulam T, LaMont JT. Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes. J Clin Invest. 1988 Jun; 81(6):1741-5.
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  115. Becker SD, Lamont JT. Postoperative jaundice. Semin Liver Dis. 1988 May; 8(2):183-90.
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  116. Zeisel SH, daCosta KA, LaMont JT. Mono-, di- and trimethylamine in human gastric fluid: potential substrates for nitrosodimethylamine formation. Carcinogenesis. 1988 Jan; 9(1):179-81.
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  117. Murray FE, O'Brien MJ, Birkett DH, Kennedy SM, LaMont JT. Diversion colitis. Pathologic findings in a resected sigmoid colon and rectum. Gastroenterology. 1987 Dec; 93(6):1404-8.
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  118. Hale WB, Turner B, LaMont JT. Oxygen radicals stimulate guinea pig gallbladder glycoprotein secretion in vitro. Am J Physiol. 1987 Nov; 253(5 Pt 1):G627-30.
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  119. Lazar HL, McCormick JR, Lamont JT, Bell R. Dysphagia lusoria associated with an esophageal carcinoma. Ann Thorac Surg. 1987 Sep; 44(3):315-7.
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  120. Triadafilopoulos G, Pothoulakis C, O'Brien MJ, LaMont JT. Differential effects of Clostridium difficile toxins A and B on rabbit ileum. Gastroenterology. 1987 Aug; 93(2):273-9.
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  121. Jaffin BW, Bliss CM, LaMont JT. Significance of occult gastrointestinal bleeding during anticoagulation therapy. Am J Med. 1987 Aug; 83(2):269-72.
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  122. Grisham MB, Von Ritter C, Smith BF, Lamont JT, Granger DN. Interaction between oxygen radicals and gastric mucin. Am J Physiol. 1987 Jul; 253(1 Pt 1):G93-6.
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  123. Smith BF, LaMont JT, Small DM. The sequence of events in gallstone formation. Lab Invest. 1987 Feb; 56(2):125-6.
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  124. Pothoulakis C, Triadafilopoulos G, Clark M, Franzblau C, LaMont JT. Clostridium difficile cytotoxin inhibits protein synthesis in fibroblasts and intestinal mucosa. Gastroenterology. 1986 Nov; 91(5):1147-53.
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  125. LaMorte WW, LaMont JT, Hale W, Booker ML, Scott TE, Turner B. Gallbladder prostaglandins and lysophospholipids as mediators of mucin secretion during cholelithiasis. Am J Physiol. 1986 Nov; 251(5 Pt 1):G701-9.
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  126. LaMont JT, Kandel GP. Toxic megacolon in ulcerative colitis. Early diagnosis and management. Hosp Pract (Off Ed). 1986 Sep 15; 21(9):102A-102D, 102H, 102K-102M passim.
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  127. Smith BF, LaMont JT. The central issue of cholesterol gallstones. Hepatology. 1986 May-Jun; 6(3):529-31.
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  128. Pothoulakis C, Barone LM, Ely R, Faris B, Clark ME, Franzblau C, LaMont JT. Purification and properties of Clostridium difficile cytotoxin B. J Biol Chem. 1986 Jan 25; 261(3):1316-21.
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  129. Pothoulakis H, Triadafilopoulos G, LaMont JT. Antibiotic-associated colitis. Compr Ther. 1985 Dec; 11(12):68-73.
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  130. Smith BF, LaMont JT. Identification of gallbladder mucin-bilirubin complex in human cholesterol gallstone matrix. Effects of reducing agents on in vitro dissolution of matrix and intact gallstones. J Clin Invest. 1985 Aug; 76(2):439-45.
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  131. LaMont JT. Cholestasis: medical or surgical? Hosp Pract (Off Ed). 1985 Feb 15; 20(2):82A, 82B, 82C passim.
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  132. Smith BF, LaMont JT. The pathogenesis of gallstones. Hosp Pract (Off Ed). 1984 Dec; 19(12):93-9, 103-4.
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  133. Smith BF, LaMont JT. Hydrophobic binding properties of bovine gallbladder mucin. J Biol Chem. 1984 Oct 10; 259(19):12170-7.
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  134. Moore JR, Turner BS, LaMont JT. Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. Am J Physiol. 1984 Oct; 247(4 Pt 1):G427-31.
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  135. LaMont JT, Smith BF, Moore JR. Role of gallbladder mucin in pathophysiology of gallstones. Hepatology. 1984 Sep-Oct; 4(5 Suppl):51S-56S.
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  136. Moore JR, LaMont JT. Colorectal cancer. Risk factors and screening strategies. Arch Intern Med. 1984 Sep; 144(9):1819-23.
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  137. Levy PF, Smith BF, LaMont JT. Human gallbladder mucin accelerates nucleation of cholesterol in artificial bile. Gastroenterology. 1984 Aug; 87(2):270-5.
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  138. Ooi W, Levine HG, LaMont JT, Clark RA. Inactivation of Clostridium difficile cytotoxin by the neutrophil myeloperoxidase system. J Infect Dis. 1984 Feb; 149(2):215-9.
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  139. Trnka YM, Lamont JT. Clostridium difficile colitis. Adv Intern Med. 1984; 29:85-107.
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  140. Smith BF, LaMont JT. Bovine gallbladder mucin binds bilirubin in vitro. Gastroenterology. 1983 Sep; 85(3):707-12.
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  141. LaMont JT, Turner BS, DiBenedetto D, Handin R, Schafer AI. Arachidonic acid stimulates mucin secretion in prairie dog gallbladder. Am J Physiol. 1983 Jul; 245(1):G92-8.
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  142. LaMont JT, Ventola AS, Trotman BW, Soloway RD. Mucin glycoprotein content of human pigment gallstones. Hepatology. 1983 May-Jun; 3(3):377-82.
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  143. LaMont JT, Turner BS, Bernstein SE, Trotman B. Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones. Hepatology. 1983 Mar-Apr; 3(2):198-200.
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  144. Lamont JT, Ventola AS, Maull EA, Szabo S. Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release. Gastroenterology. 1983 Feb; 84(2):306-13.
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  145. Stambler JB, Klibaner MI, Bliss CM, LaMont JT. Tuberculous abscess of the pancreas. Gastroenterology. 1982 Oct; 83(4):922-5.
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  146. Levine HG, Lamont JT. Diarrhea we can treat: antibiotic-associated colitis. Compr Ther. 1982 Aug; 8(8):36-43.
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  147. Levine HG, Kennedy M, LaMont JT. Counterimmunoelectrophoresis vs. cytotoxicity assay for the detection of Clostridium difficile toxin. J Infect Dis. 1982 Mar; 145(3):398.
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  148. LaMont JT. Recommendations for inflammatory bowel disease. Geriatrics. 1982 Mar; 37(3):93-6, 102, 105.
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  149. LaMont JT. Gallbladder mucin glycoprotein hypersecretion in experimental cholelithiasis: role of mucin gel in nucleation of cholesterol gallstones. Adv Exp Med Biol. 1982; 144:231-4.
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  150. Lee SP, LaMont JT, Carey MC. Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones. J Clin Invest. 1981 Jun; 67(6):1712-23.
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  151. Popp JW, Harrist TJ, Dienstag JL, Bhan AK, Wands JR, LaMont JT, Mihm MC. Cutaneous vasculitis associated with acute and chronic hepatitis. Arch Intern Med. 1981 Apr; 141(5):623-9.
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  152. Trnka YM, LaMont JT. Association of Clostridium difficile toxin with symptomatic relapse of chronic inflammatory bowel disease. Gastroenterology. 1981 Apr; 80(4):693-6.
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  153. Lee SP, Carey MC, LaMont JT. Aspirin prevention of cholesterol gallstone formation in prairie dogs. Science. 1981 Mar 27; 211(4489):1429-31.
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  154. LaMont JT, Ventola AS. Purification and composition of colonic epithelial mucin. Biochim Biophys Acta. 1980 Nov 20; 626(1):234-43.
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  155. Lamont JT, Ventola A. Synthesis and secretion of colonic glycoproteins: evidence for shedding in vivo of low molecular weight membrane components. Biochim Biophys Acta. 1980 May 22; 629(3):553-65.
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  156. LaMont JT, Trnka YM. Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease. Lancet. 1980 Feb 23; 1(8165):381-3.
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  157. LaMont JT, Sonnenblick EB, Rothman S. Role of clostridial toxin in the pathogenesis of clindamycin colitis in rabbits. Gastroenterology. 1979 Feb; 76(2):356-61.
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  158. LaMont JT, O'Gorman TA. Experimental colon cancer. Gastroenterology. 1978 Dec; 75(6):1157-69.
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  159. O'Gorman TA, LaMont JT. Glycoprotein synthesis and secretion in human colon cancers and normal colonic mucosa. Cancer Res. 1978 Sep; 38(9):2784-9.
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  160. LaMont JT, Ventola A. Galactosyltransferase in fetal, neonatal, and adult colon: relationship to differentiation. Am J Physiol. 1978 Aug; 235(2):E213-7.
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  161. Rampal P, LaMont JT, Trier JS. Differentiation of glycoprotein synthesis in fetal rat colon. Am J Physiol. 1978 Aug; 235(2):E207-12.
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  162. Katz L, LaMont JT, Trier JS, Sonnenblick EB, Rothman SW, Broitman SA, Rieth S. Experimental clindamycin-associated colitis in rabbits. Evidence of toxin-mediated mucosal damage. Gastroenterology. 1978 Feb; 74(2 Pt 1):246-52.
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  163. LaMont JT, Gammon MT, Isselbacher KJ. Cell-surface glycosyltransferases in cultured fibroblasts: increased activity and release during serum stimulation of growth. Proc Natl Acad Sci U S A. 1977 Mar; 74(3):1086-90.
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  164. LaMont JT, Isselbacher KJ. The effects of neuraminidase on concanavalin A agglutination of erythrocytes: evidence for adsorption of neuraminidase to erythrocyte membrane. J Cell Physiol. 1977 Mar; 90(3):565-72.
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  165. LaMont JT, Ventola A. Stimulation of colonic glycoprotein synthesis by dibutyryl cyclic AMP and theophylline. Gastroenterology. 1977 Jan; 72(1):82-6.
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  166. Baranowski K, Greene HL, Lamont JT. Viral hepatitis; how to reduce its threat to the patient and others (including you). Nursing. 1976 May; 6(5):31-8.
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  167. Wands JR, LaMont JT, Mann E, Isselbacher KJ. Arthritis associated with intestinal-bypass procedure for morbid obesity. Complement activation and characterization of circulating cryoproteins. N Engl J Med. 1976 Jan 15; 294(3):121-4.
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  168. LaMont JT, Isselbacher KJ. Current concepts of postoperative hepatic dysfunction. Conn Med. 1975 Aug; 39(8):461-4.
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  169. Weiser MM, Lamont JT, Walker WA. Editorial: Alpha 1-antitrypsin deficiency - a defect of secretion. N Engl J Med. 1975 Jan 23; 292(4):205-6.
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  170. LaMont JT, Isselbacher KJ. Alterations in glycosyltransferase activity in human colon cancer. J Natl Cancer Inst. 1975 Jan; 54(1):53-56.
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  171. LaMont JT, Weiser MM, Isselbacher KJ. Cell surface glycosyltransferase activity in normal and neoplastic intestinal epithelium of the rat. Cancer Res. 1974 Dec; 34(12):3225-8.
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  172. Powell LW, LaMont JT, Isselbacher KJ. Haemolysis in experimental cholestasis: possible role of erythrocyte sialic acid. Gut. 1974 Oct; 15(10):794-8.
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  173. Lamont JT, Perrotto JL, Weiser MM, Isselbacher KJ. Cell surface galactosyltransferase and lectin agglutination of thymus and spleen lymphocytes. Proc Natl Acad Sci U S A. 1974 Sep; 71(9):3726-30.
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  174. LaMont JT. Postoperative juandice. Surg Clin North Am. 1974 Jun; 54(3):637-45.
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  175. LaMont JT. Ethics of renal biopsy. Ann Intern Med. 1974 Apr; 80(4):560.
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  176. LaMont JT, Isselbacher KJ. Postoperative jaundice. N Engl J Med. 1973 Feb 8; 288(6):305-7.
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