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John Eric Jensen, PH.D.

TitleAssistant Professor of Psychiatry
InstitutionMcLean Hospital
DepartmentPsychiatry
AddressMclean Hospital
Brain Imaging Center
115 Mill St
Belmont MA 02478
Phone617/855-2000
Fax617/855-2880

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Silveri MM, Jensen JE, Rosso IM, Sneider JT, Yurgelun-Todd DA. Preliminary evidence for white matter metabolite differences in marijuana-dependent young men using 2D J-resolved magnetic resonance spectroscopic imaging at 4 Tesla. Psychiatry Res. 2011 Mar 31; 191(3):201-11.
    View in: PubMed
  2. Forester BP, Berlow YA, Harper DG, Jensen JE, Lange N, Froimowitz MP, Ravichandran C, Iosifescu DV, Lukas SE, Renshaw PF, Cohen BM. Age-related changes in brain energetics and phospholipid metabolism. NMR Biomed. 2010 Apr; 23(3):242-50.
    View in: PubMed
  3. Ongür D, Prescot AP, Jensen JE, Rouse ED, Cohen BM, Renshaw PF, Olson DP. T2 relaxation time abnormalities in bipolar disorder and schizophrenia. Magn Reson Med. 2010 Jan; 63(1):1-8.
    View in: PubMed
  4. Brennan BP, Hudson JI, Jensen JE, McCarthy J, Roberts JL, Prescot AP, Cohen BM, Pope HG, Renshaw PF, Ongür D. Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzole. Neuropsychopharmacology. 2010 Feb; 35(3):834-46.
    View in: PubMed
  5. Trksak GH, Jensen JE, Plante DT, Penetar DM, Tartarini WL, Maywalt MA, Brendel M, Dorsey CM, Renshaw PF, Lukas SE. Effects of sleep deprivation on sleep homeostasis and restoration during methadone-maintenance: a [31]P MRS brain imaging study. Drug Alcohol Depend. 2010 Jan 15; 106(2-3):79-91.
    View in: PubMed
  6. Forester BP, Harper DG, Jensen JE, Ravichandran C, Jordan B, Renshaw PF, Cohen BM. 31Phosphorus magnetic resonance spectroscopy study of tissue specific changes in high energy phosphates before and after sertraline treatment of geriatric depression. Int J Geriatr Psychiatry. 2009 Aug; 24(8):788-97.
    View in: PubMed
  7. Jensen JE, Licata SC, Ongür D, Friedman SD, Prescot AP, Henry ME, Renshaw PF. Quantification of J-resolved proton spectra in two-dimensions with LCModel using GAMMA-simulated basis sets at 4 Tesla. NMR Biomed. 2009 Aug; 22(7):762-9.
    View in: PubMed
  8. Ongür D, Prescot AP, Jensen JE, Cohen BM, Renshaw PF. Creatine abnormalities in schizophrenia and bipolar disorder. Psychiatry Res. 2009 Apr 30; 172(1):44-8.
    View in: PubMed
  9. Kaufman RE, Ostacher MJ, Marks EH, Simon NM, Sachs GS, Jensen JE, Renshaw PF, Pollack MH. Brain GABA levels in patients with bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30; 33(3):427-34.
    View in: PubMed
  10. Licata SC, Jensen JE, Penetar DM, Prescot AP, Lukas SE, Renshaw PF. A therapeutic dose of zolpidem reduces thalamic GABA in healthy volunteers: a proton MRS study at 4 T. Psychopharmacology (Berl). 2009 May; 203(4):819-29.
    View in: PubMed
  11. David G. Harper, Eric Jensen, Caitlin Ravichandran, Grace da Cunha, David P Olson, Perry Renshaw. Brain GABA and NAA are associated with beta-NTP levels in the Healthy Human Brain: A Dual-Nuclear 1H/31P MRSI Study at 4 Tesla. ISMRM Workshop. 2008; accepted.
  12. Stephanie C. Licata, J. Eric Jensen, David M. Penetar, Scott E. Lukas, Perry F. Renshaw . A therapeutic dose of zolpidem reduces thalamic GABA in healthy volunteers: A proton MRS study at 4 Tesla. ISMRM Workshop. 2008; accepted.
  13. Dan V. Iosifescu, J. Eric Jensen, Carissa L. Medeiros, Victoria E. Ameral, Andrew A. Nierenberg, Maurizio Fava, Perry F. Renshaw. Concomitant Changes In Neurotransmitter Levels And In Brain Bioenergetics During The Treatment Of Major Depressive Disorder. ISMRM Workshop. 2008; accepted.
  14. Agarwal N, Forester BP, Jensen E, Zuo C, Renshaw P. Alterations In Brain N-Acetyl Aspartyl Glutamate Levels In Geriatric Depression. ISMRM Workshop. 2008; accepted.
  15. Caitlin Ravichandran, David G. Harper, Eric Jensen, Perry Renshaw. Simulation Study Comparing Statistical Methods for Modeling the Association Between Proton MRS and Phosphorous MRS Metabolite Measurements in Vivo. ISMRM Workshop. 2008; accepted.
  16. Dost Ongur, Andy P. Prescot, J. Eric Jensen, Caitlin Stork, Miriam Lundy, Ian Greenhouse, Bruce M. Cohen, Perry F. Renshaw, . Abnormal Glutamatergic Neurotransmission and Neuronal-Glial Interactions in Acute Mania. ISMRM Workshop. 2008; accepted.
  17. David P Olson, Dost Ongur, J. Eric Jensen, Andrew P. Prescot, Perry F. Renshaw. Metabolite T2 Relaxation Time Abnormalities in Bipolar Disorder and Schizophrenia. ISMRM Workshop. 2008; accepted.
  18. Brent P. Forester, David G. Harper, J. Eric Jensen, Caitlin Ravichandran, Perry F. Renshaw, Bruce M. Cohen. 31Phosphorus Magnetic Resonance Spectroscopy Study of Tissue Specific Changes in High Energy Phosphates Before and After Sertraline Treatment of Geriatric Depression. ISMRM Workshop. 2008; accepted.
  19. Winkelman JW, Buxton OM, Jensen JE, Benson KL, O'Connor SP, Wang W, Renshaw PF. Reduced brain GABA in primary insomnia: preliminary data from 4T proton magnetic resonance spectroscopy (1H-MRS). Sleep. 2008 Nov; 31(11):1499-506.
    View in: PubMed
  20. Silveri MM, Dikan J, Ross AJ, Jensen JE, Kamiya T, Kawada Y, Renshaw PF, Yurgelun-Todd DA. Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy. NMR Biomed. 2008 Nov; 21(10):1066-75.
    View in: PubMed
  21. Silveri MM, Jensen JE, McCaffrey AC, Racine M, Yurgelun-Todd DA. Examining the association between frontal lobe GABA metabolite levels and binge alcohol consumption: A 4.0 Tesla magnetic resonance spectroscopy. International Society for Magnetic Resonance in Medicine. 2008.
  22. Ongür D, Jensen JE, Prescot AP, Stork C, Lundy M, Cohen BM, Renshaw PF. Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania. Biol Psychiatry. 2008 Oct 15; 64(8):718-26.
    View in: PubMed
  23. Jensen JE, Daniels M, Haws C, Bolo NR, Lyoo IK, Yoon SJ, Cohen BM, Stoll AL, Rusche JR, Renshaw PF. Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients. Exp Clin Psychopharmacol. 2008 Jun; 16(3):199-206.
    View in: PubMed
  24. Pollack MH, Jensen JE, Simon NM, Kaufman RE, Renshaw PF. High-field MRS Study of GABA, Glutamate and Glutamine in Social Anxiety Disorder: Response to Treatment with Levetiracetam. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2008; 32(3):739-43.
  25. Iosifescu DV, Bolo NR, Nierenberg AA, Jensen JE, Fava M, Renshaw PF. Brain bioenergetics and response to triiodothyronine augmentation in major depressive disorder. Biol Psychiatry. 2008 Jun 15; 63(12):1127-34.
    View in: PubMed
  26. Silveri MM, Jensen JE, Sneider JT, Sava SS, Yurgelun-Todd DA. Neurochemical profiles associated with chronic alcohol consumption. American Psychological Association. 2008.
  27. D Ongur, AP Prescot, JE Jensen, C Stork, M Lundy, BM Cohen, PF Renshaw. MRS studies of glutamatergic neurotransmission in bipolar disorder. American College of Neuropsychopharmacology (ACNP), Boca Rato, FL. 2007.
  28. Pollack MH, Jensen JE, Simon NM, Kaufman RE, Renshaw PF. High-field MRS study of GABA, glutamate and glutamine in social anxiety disorder: response to treatment with levetiracetam. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 1; 32(3):739-43.
    View in: PubMed
  29. Trksak GH, Jensen JE, Renshaw PF, Lukas SE. Brain phosphorus magnetic resonance spectroscopy imaging of sleep homeostasis and restoration in drug dependence. ScientificWorldJournal. 2007; 7:217-22.
    View in: PubMed
  30. MM Silveri, J Dikan, AJ Ross, JE Jensen, T Kamiya, Y Kawada, PF Renshaw, DA Yurglun-Todd. Oral Citicholine Supplementation Significantly Alters Phosphorus Metabolites in the Anterior Cingulate Cortex. 2007.
  31. Streeter C, Jensen JE, Perlmutter RM, Cabral HJ, Tian H, Terhune DB, Ciraulo DA, Renshaw PF. Yoga Asana Sessions Increase Brain GABA Levels: A Pilot Study. . Journal of Alternative and Complimentary Medicine. 2007; 13(4):419-26.
  32. Iosifescu DV, Jensen JE, Nierenberg AA, Charles D, Bolo NR, Fava M, Renshaw PF. Mitochondrial Function In The Anterior Cingulate and Treatment Response In MDD. American Psychiatric Association 160th Annual Meeting (APA). 2007.
  33. Iosifescu DV, Jensen JE, Nierenberg AA, Bolo NR, Fava M, Renshaw PF. Bioenergetic Metabolism During Antidepressant Treatment In MDD. Biological Psychiatry. 2007.
  34. Friedman SD, Jensen JE, Frederick BB, Artu AA, Renshaw PF, Dager SR . Brain changes to hypocapnia using rapidly interleaved phosphorus-proton magnetic resonance spectroscopy at 4 Tesla. Journal of Cerebral Blood Flow and Metabolism. 2007; 27(3):646-53.
  35. Brent P. Forester MD, Yosef A. Berlow BSc, J. Eric Jensen PhD, Thomas M Cooper BA, Dan V Iosifescu MD, Scott E. Lukas PhD, Perry F. Renshaw MD PhD. Age-Related Changes in Brain Energy Metabolites. American Association for Geriatric Psychiatry (AAGP). 2007.
  36. Théberge J, Jensen JE, Rowland LM. Regarding "Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study". Biol Psychiatry. 2007 May 15; 61(10):1218-9; author reply 1219-20.
    View in: PubMed
  37. Jensen JE, Frederick B, Renshaw PF. J-Resolved Proton Echo-Planar Spectroscopic Imaging of GABA in the Human Brain at 4 Tesla. Proceedings of the International Society of Magnetic Resonance in Medicine. 2006; 0(0):0.
  38. David P. Olson, Amy Ross, Stephen M. Strakowski, Staci A. Gruber, Eric Jensen, James C. Eliassen, Wen-Jang Chu, Jing-Huei Lee, Caleb M. Adler, Earle E. Bain, Mary Kujawa, Georges Gharabawi, Perry F. Renshaw, Deborah A. Yurgelun-Todd. Altered Metabolite Concentrations in the Brains of Frequently Relapsing Bipolar Patients Treated with Long-Acting Injectable (LAI) Risperidone. Society of Biological Psychiatry. 2006.
  39. J. Eric Jensen, Blaise Frederick, Perry F. Renshaw. J-Resolved Proton Echo-Planar Spectroscopic Imaging of GABA in the Human Brain. International Society of Magnetic Resonance in Medicine. 2006.
  40. Marro K, Friedman SD, Hyyti O, Jensen JE, Frederick BB. CASL artifacts due to resonant frequency shifts during metabolic activity. 2006.
  41. Prescot AP, Frederick BD, Wang L, Brown J, Jensen JE, Kaufman MJ, Renshaw PF. In vivo detection of brain glycine with echo-time-averaged (1)H magnetic resonance spectroscopy at 4.0 T. Magnetic Resonance in Medicine. 2006; 55(3):681-686.
  42. Prescot AP, de B Frederick B, Wang L, Brown J, Jensen JE, Kaufman MJ, Renshaw PF. In vivo detection of brain glycine with echo-time-averaged (1)H magnetic resonance spectroscopy at 4.0 T. Magn Reson Med. 2006 Mar; 55(3):681-6.
    View in: PubMed
  43. Jensen JE, Miller J, Williamson PC, Neufeld RW, Menon RS, Malla A, Manchanda R, Schaefer B, Densmore M, Drost DJ. Grey and white matter differences in brain energy metabolism in first episode schizophrenia: 31P-MRS chemical shift imaging at 4 Tesla. Psychiatry Res. 2006 Mar 31; 146(2):127-35.
    View in: PubMed
  44. Jensen JE, Frederick Bde B, Renshaw PF. Grey and white matter GABA level differences in the human brain using two-dimensional, J-resolved spectroscopic imaging. NMR Biomed. 2005 Dec; 18(8):570-6.
    View in: PubMed
  45. Streeter CC, Hennen J, Ke Y, Jensen JE, Sarid-Segal O, Nassar LE, Knapp C, Meyer AA, Kwak T, Renshaw PF, Ciraulo DA. Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment. Psychopharmacology (Berl). 2005 Nov; 182(4):516-26.
    View in: PubMed
  46. Jensen JE, Frederick BD, Wang L, Brown J, Renshaw PF. Two-dimensional, J-resolved spectroscopic imaging of GABA at 4 Tesla in the human brain. Magn Reson Med. 2005 Oct; 54(4):783-8.
    View in: PubMed
  47. Dorsey Cynthia, Jensen Eric, Kaufman Marc, Tartarini Wendy, Juliano Patricia, Hennen John, Renshaw Perry, Lukas Scott . Brain Chemistry Changes After Total Sleep Deprivation: Individual Differences. Associated Professional Sleep Societies (APSS), 19th Annual Meeting. 2005.
  48. Miller JE, Jensen JE, Williamson PC, Menon RS, Neufeld J, Drost DJ . Longitudinal 31P Magnetic Resonance Spectroscopy of Membrane Metabolism in Schizophrenia. Proceedings of the International Society of Magnetic Resonance in Medicine. 2005.
  49. Jensen JE, Miller J, Williamson PC, Neufeld RWJ, Menon RS, Schaefer B, Densmore M, Drost DJ. Memantine as a Neuroprotective Treatment in Schizophrenia [letter]. British Journal of Psychiatry. 2005; 186:77-78.
  50. J. Eric Jensen, Perry F. Renshaw, Dean F. Wong, Weiguo Ye. Neuroimaging. Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 2005; 939-961.
  51. Théberge J, Al-Semaan Y, Jensen JE, Williamson PC, Neufeld RW, Menon RS, Schaefer B, Densmore M, Drost DJ. Comparative study of proton and phosphorus magnetic resonance spectroscopy in schizophrenia at 4 Tesla. Psychiatry Res. 2004 Nov 15; 132(1):33-9.
    View in: PubMed
  52. Jensen JE, Mileti C, Barros T, Yurgelun-Todd D, Kaufman MJ, Renshaw PF, Pollack MJ. Brain 31P-MRS at 4.0 Tesla: Methadone-maintenance therapy for opiate addiction. Proceedings of the International Society of Magnetic Resonance in Medicine. 2004.
  53. Jensen JE, Hirashima F, Cohen BM, Stoll AL, Frederic BD, Renshaw PF. Brain 31P-MRS at 4.0 Tesla: Effects of Triacetyluridine (TAU) in the treatment of mood disorders. Proceedings of the International Society of Magnetic Resonance in Medicine. 2004.
  54. Jensen JE, Frederic BD, Wang L, Brown J, Renshaw PF . In vivo two-dimensional J-resolved GABA MRSI at 4.0 Tesla. Proceedings of the International Society of Magnetic Resonance in Medicine. 2004.
  55. Miller JE, Jensen JE, Williamson PC, Manchanda R, Menon RS, Neufeld J, Drost DJ . A 4.0T 31P Magnetic Resonance Spectroscopy Study of Chronic and First-Episode Schizophrenia. Proceedings of the International Society of Magnetic Resonance in Medicine. 2004.
  56. Jensen JE, Miller J, Williamson PC, Neufeld RW, Menon RS, Malla A, Manchanda R, Schaefer B, Densmore M, Drost DJ. Focal changes in brain energy and phospholipid metabolism in first-episode schizophrenia: 31P-MRS chemical shift imaging study at 4 Tesla. Br J Psychiatry. 2004 May; 184:409-15.
    View in: PubMed
  57. Iosifescu DV, Bolo NR, Jensen JE, Nierenberg AA, Ryan JR, Renshaw PF, Fava M. Brain bioenergetics and thyroid hormone treatment in MDD. American Psychiatric Association Annual Meeting (APA). 2004.
  58. Iosifescu DV, Bolo NR, Jensen JE, Nierenberg AA, Ryan JR, Renshaw PF, Fava M. The Antidepressant Efficacy of T3 Augmentation Treatment in MDD is Associated with Increased Brain Energy Metabolism. American College of Neuropsychopharmacology (ACNP) 42nd Annual Meeting. 2003.
  59. Jensen JE, Drost DJ, Menon RS, Williamson PC. In vivo brain (31)P-MRS: measuring the phospholipid resonances at 4 Tesla from small voxels. NMR Biomed. 2002 Aug; 15(5):338-47.
    View in: PubMed
  60. Jensen, John Eric Nestler . High-Field In vivo Magnetic Resonance Spectroscopy: Optimization and Application to the Study of Schizophrenia [doctoral thesis]. 2002.
  61. Barberi EA, Gati JS, Jensen JE, Bartha R, Drost DJ, Menon RS. A Multiply-Tuned Hybrid Birdcage Volume Resonator for Transmit/Receive and Transmit-Only High Field NMR Imaging Spectroscopy, and Multinuclear Phased Array Applications. Proceedings of the International Society of Magnetic Resonance in Medicine. 2002.
  62. Jensen JE, Williamson PC, Neufeld RWJ, Menon RS, Malla A, Drost DJ . Localized Alterations in Brain Phospholipid Metabolism in First-Episode Schizophrenic Patients: A 31P-MRS Chemical-Shift Imaging at 4 Tesla. Proceedings of the International Society of Magnetic Resonance in Medicine. 2002.
  63. Jensen JE, Al-Semaan YM, Williamson PC, Neufeld RW, Menon RS, Schaeffer B, Densmore M, Drost DJ. Region-specific changes in phospholipid metabolism in chronic, medicated schizophrenia: (31)P-MRS study at 4.0 Tesla. Br J Psychiatry. 2002 Jan; 180:39-44.
    View in: PubMed
  64. Al-Semaan YM, Jensen JE, Williamson PC, Drost DJ, Menon RS, Neufeld RWJ. Region-Specific Changes in Phosphorus Metabolites in Chronic-Medicated Schizophrenic Patients: A 31P-Chemical-Shift Imaging Study at 4.0 Tesla. International Congress On Schizophrenia Research. 2001.
  65. Jensen JE, Al-Semaan YM, Drost DJ, Schaefer B, Neufeld RWJ, Williamson PC, Menon RS. Region-Specific Changes in Brain Phospholipid Metabolism in Chronic Schizophrenics: A 31P-Chemical-Shift Imaging Study at 4.0 Tesla. Proceedings of the International Society of Magnetic Resonance in Medicine. 2001.
  66. Jensen JE, Drost DJ, Williamson PC, Menon RS. Improved Spatial Resolution in 31P Brain Spectroscopic Imaging at 4.0T: Implications for the Clinical Study of Membrane Metabolites. Proceedings of the International Society of Magnetic Resonance in Medicine. 2000.
  67. Jensen JE, Drost DJ, Williamson PC, Menon RS. Comparing In vivo Brain Spectroscopy: 1.5T 1H-Decoupled vs 4.0T 1H-Coupled in Normal Human Volunteers. Proceedings of the International Society of Magnetic Resonance in Medicine. 1999.
  68. Henderson E, Sykes J, Jensen JE, Pereira RS, Drost DJ, Rutt BK, Prato FS, Weinmann HJ, Lee TY. Differences Between the Kinetics of Two MR Contrast Agents In A Canine Spontaneous Breast Tumour Model. 1998.
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