Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Roy Kishony, Ph.D.

TitleVisiting Professor of Systems Biology
InstitutionHarvard Medical School
DepartmentSystems Biology
AddressHarvard Medical School
Systems Biology Alpert 519
200 Longwood Ave
Boston MA 02115
Phone617/432-6390

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Schultz D, Kishony R. Optimization and control in bacterial Lag phase. BMC Biol. 2013; 11:120.
    View in: PubMed
  2. Lieberman TD, Flett KB, Yelin I, Martin TR, McAdam AJ, Priebe GP, Kishony R. Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures. Nat Genet. 2014 Jan; 46(1):82-7.
    View in: PubMed
  3. Toprak E, Veres A, Yildiz S, Pedraza JM, Chait R, Paulsson J, Kishony R. Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition. Nat Protoc. 2013 Feb 21; 8(3):555-67.
    View in: PubMed
  4. Palmer AC, Kishony R. Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance. Nat Rev Genet. 2013 Apr; 14(4):243-8.
    View in: PubMed
  5. Yao Z, Kahne D, Kishony R. Distinct Single-Cell Morphological Dynamics under Beta-Lactam Antibiotics. Mol Cell. 2012 Dec 14; 48(5):705-12.
    View in: PubMed
  6. Yao Z, Davis RM, Kishony R, Kahne D, Ruiz N. Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):E2561-8.
    View in: PubMed
  7. Skurnik D, Davis MR, Benedetti D, Moravec KL, Cywes-Bentley C, Roux D, Traficante DC, Walsh RL, Maira-Litràn T, Cassidy SK, Hermos CR, Martin TR, Thakkallapalli EL, Vargas SO, McAdam AJ, Lieberman TD, Kishony R, Lipuma JJ, Pier GB, Goldberg JB, Priebe GP. Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection. J Infect Dis. 2012 Jun; 205(11):1709-18.
    View in: PubMed
  8. Ernebjerg M, Kishony R. Distinct growth strategies of soil bacteria as revealed by large-scale colony tracking. Appl Environ Microbiol. 2012 Mar; 78(5):1345-52.
    View in: PubMed
  9. Toprak E, Veres A, Michel JB, Chait R, Hartl DL, Kishony R. Evolutionary paths to antibiotic resistance under dynamically sustained drug selection. Nat Genet. 2012 Jan; 44(1):101-5.
    View in: PubMed
  10. Chait R, Vetsigian K, Kishony R. What counters antibiotic resistance in nature? Nat Chem Biol. 2012 Jan; 8(1):2-5.
    View in: PubMed
  11. Lieberman TD, Michel JB, Aingaran M, Potter-Bynoe G, Roux D, Davis MR, Skurnik D, Leiby N, LiPuma JJ, Goldberg JB, McAdam AJ, Priebe GP, Kishony R. Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes. Nat Genet. 2011 Dec; 43(12):1275-80.
    View in: PubMed
  12. Bush K, Courvalin P, Dantas G, Davies J, Eisenstein B, Huovinen P, Jacoby GA, Kishony R, Kreiswirth BN, Kutter E, Lerner SA, Levy S, Lewis K, Lomovskaya O, Miller JH, Mobashery S, Piddock LJ, Projan S, Thomas CM, Tomasz A, Tulkens PM, Walsh TR, Watson JD, Witkowski J, Witte W, Wright G, Yeh P, Zgurskaya HI. Tackling antibiotic resistance. Nat Rev Microbiol. 2011 Dec; 9(12):894-6.
    View in: PubMed
  13. Vetsigian K, Jajoo R, Kishony R. Structure and evolution of Streptomyces interaction networks in soil and in silico. PLoS Biol. 2011 Oct; 9(10):e1001184.
    View in: PubMed
  14. Kishony R, Hatzimanikatis V. Systems biology. Curr Opin Biotechnol. 2011 Aug; 22(4):538-40.
    View in: PubMed
  15. Bollenbach T, Kishony R. Resolution of gene regulatory conflicts caused by combinations of antibiotics. Mol Cell. 2011 May 20; 42(4):413-25.
    View in: PubMed
  16. Ernebjerg M, Kishony R. Dynamic phenotypic clustering in noisy ecosystems. PLoS Comput Biol. 2011 Mar; 7(3):e1002017.
    View in: PubMed
  17. Chait R, Shrestha S, Shah AK, Michel JB, Kishony R. A differential drug screen for compounds that select against antibiotic resistance. PLoS One. 2010; 5(12):e15179.
    View in: PubMed
  18. Torella JP, Chait R, Kishony R. Correction: optimal drug synergy in antimicrobial treatments. PLoS Comput Biol. 2010; 6(7).
    View in: PubMed
  19. Torella JP, Chait R, Kishony R. Correction: optimal drug synergy in antimicrobial treatments. PLoS Comput Biol. 2010 Jun; 6(6).
    View in: PubMed
  20. Torella JP, Chait R, Kishony R. Optimal drug synergy in antimicrobial treatments. PLoS Comput Biol. 2010 Jun; 6(6):e1000796.
    View in: PubMed
  21. DeLuna A, Springer M, Kirschner MW, Kishony R. Need-based up-regulation of protein levels in response to deletion of their duplicate genes. PLoS Biol. 2010 Mar; 8(3):e1000347.
    View in: PubMed
  22. Palmer AC, Angelino E, Kishony R. Chemical decay of an antibiotic inverts selection for resistance. Nat Chem Biol. 2010 Feb; 6(2):105-7.
    View in: PubMed
  23. Bollenbach T, Kishony R. Hydroxyurea triggers cellular responses that actively cause bacterial cell death. Mol Cell. 2009 Dec 11; 36(5):728-9.
    View in: PubMed
  24. Chung HS, Yao Z, Goehring NW, Kishony R, Beckwith J, Kahne D. Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery. Proc Natl Acad Sci U S A. 2009 Dec 22; 106(51):21872-7.
    View in: PubMed
  25. Bollenbach T, Quan S, Chait R, Kishony R. Nonoptimal microbial response to antibiotics underlies suppressive drug interactions. Cell. 2009 Nov 13; 139(4):707-18.
    View in: PubMed
  26. Bollenbach T, Kishony R. Quiet gene circuit more fragile than its noisy peer. Cell. 2009 Oct 30; 139(3):460-1.
    View in: PubMed
  27. Swoboda JG, Meredith TC, Campbell J, Brown S, Suzuki T, Bollenbach T, Malhowski AJ, Kishony R, Gilmore MS, Walker S. Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. ACS Chem Biol. 2009 Oct 16; 4(10):875-83.
    View in: PubMed
  28. Yeh PJ, Hegreness MJ, Aiden AP, Kishony R. Drug interactions and the evolution of antibiotic resistance. Nat Rev Microbiol. 2009 Jun; 7(6):460-6.
    View in: PubMed
  29. Michel JB, Yeh PJ, Chait R, Moellering RC, Kishony R. Drug interactions modulate the potential for evolution of resistance. Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):14918-23.
    View in: PubMed
  30. Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R. Accelerated evolution of resistance in multidrug environments. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13977-81.
    View in: PubMed
  31. Shoresh N, Hegreness M, Kishony R. Evolution exacerbates the paradox of the plankton. Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34):12365-9.
    View in: PubMed
  32. Pearl S, Gabay C, Kishony R, Oppenheim A, Balaban NQ. Nongenetic individuality in the host-phage interaction. PLoS Biol. 2008 May 20; 6(5):e120.
    View in: PubMed
  33. DeLuna A, Vetsigian K, Shoresh N, Hegreness M, Colón-González M, Chao S, Kishony R. Exposing the fitness contribution of duplicated genes. Nat Genet. 2008 May; 40(5):676-81.
    View in: PubMed
  34. Presser A, Elowitz MB, Kellis M, Kishony R. The evolutionary dynamics of the Saccharomyces cerevisiae protein interaction network after duplication. Proc Natl Acad Sci U S A. 2008 Jan 22; 105(3):950-4.
    View in: PubMed
  35. Chait R, Craney A, Kishony R. Antibiotic interactions that select against resistance. Nature. 2007 Apr 5; 446(7136):668-71.
    View in: PubMed
  36. Bollenbach T, Vetsigian K, Kishony R. Evolution and multilevel optimization of the genetic code. Genome Res. 2007 Apr; 17(4):401-4.
    View in: PubMed
  37. Yeh P, Kishony R. Networks from drug-drug surfaces. Mol Syst Biol. 2007; 3:85.
    View in: PubMed
  38. Hegreness M, Kishony R. Analysis of genetic systems using experimental evolution and whole-genome sequencing. Genome Biol. 2007; 8(1):201.
    View in: PubMed
  39. Yeh P, Tschumi AI, Kishony R. Functional classification of drugs by properties of their pairwise interactions. Nat Genet. 2006 Apr; 38(4):489-94.
    View in: PubMed
  40. Hegreness M, Shoresh N, Hartl D, Kishony R. An equivalence principle for the incorporation of favorable mutations in asexual populations. Science. 2006 Mar 17; 311(5767):1615-7.
    View in: PubMed
  41. Kussell E, Kishony R, Balaban NQ, Leibler S. Bacterial persistence: a model of survival in changing environments. Genetics. 2005 Apr; 169(4):1807-14.
    View in: PubMed
  42. Segrè D, Deluna A, Church GM, Kishony R. Modular epistasis in yeast metabolism. Nat Genet. 2005 Jan; 37(1):77-83.
    View in: PubMed
  43. Kishony R, Leibler S. Environmental stresses can alleviate the average deleterious effect of mutations. J Biol. 2003; 2(2):14.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Kishony's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_