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Kamran Badizadegan, M.D.

TitleAssociate Professor of Health Sciences and Technology
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology
AddressMassachusetts General Hospital
Pathology
55 Fruit St
Boston MA 02114
Phone617/355-7315
Fax617/726-7474

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Khor TS, Badizadegan K, Ferrone C, Fernández-Del Castillo C, Desai GS, Saenz A, Le L, Lauwers GY, Deshpande V. Acinar cystadenoma of the pancreas: a clinicopathologic study of 10 cases including multilocular lesions with mural nodules. Am J Surg Pathol. 2012 Nov; 36(11):1579-91.
    View in: PubMed
  2. Zella GC, Gee MS, Badizadegan K. Case records of the Massachusetts General Hospital. Case 25-2012. A 15-year-old boy with abdominal pain, hematochezia, and anemia. N Engl J Med. 2012 Aug 16; 367(7):659-67.
    View in: PubMed
  3. Melendez E, Goldstein AM, Sagar P, Badizadegan K. Case records of the Massachusetts General Hospital. Case 3-2012. A newborn boy with vomiting, diarrhea, and abdominal distention. N Engl J Med. 2012 Jan 26; 366(4):361-72.
    View in: PubMed
  4. Badizadegan K, Thompson KM. Value of information in nonfocal colonic biopsies. J Pediatr Gastroenterol Nutr. 2011 Dec; 53(6):679-83.
    View in: PubMed
  5. Mirkovic J, Lau C, McGee S, Crum C, Badizadegan K, Feld M, Stier E. Detecting high-grade squamous intraepithelial lesions in the cervix with quantitative spectroscopy and per-patient normalization. Biomed Opt Express. 2011 Oct 1; 2(10):2917-25.
    View in: PubMed
  6. Garay J, D'Angelo JA, Park Y, Summa CM, Aiken ML, Morales E, Badizadegan K, Fiebiger E, Dickinson BL. Crosstalk between PKA and Epac regulates the phenotypic maturation and function of human dendritic cells. J Immunol. 2010 Sep 15; 185(6):3227-38.
    View in: PubMed
  7. Park Y, Best CA, Badizadegan K, Dasari RR, Feld MS, Kuriabova T, Henle ML, Levine AJ, Popescu G. Measurement of red blood cell mechanics during morphological changes. Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15):6731-6.
    View in: PubMed
  8. Lue N, Choi W, Popescu G, Yaqoob Z, Badizadegan K, Dasari RR, Feld MS. Live cell refractometry using Hilbert phase microscopy and confocal reflectance microscopy. J Phys Chem A. 2009 Nov 26; 113(47):13327-30.
    View in: PubMed
  9. McGee S, Mardirossian V, Elackattu A, Mirkovic J, Pistey R, Gallagher G, Kabani S, Yu CC, Wang Z, Badizadegan K, Grillone G, Feld MS. Anatomy-based algorithms for detecting oral cancer using reflectance and fluorescence spectroscopy. Ann Otol Rhinol Laryngol. 2009 Nov; 118(11):817-26.
    View in: PubMed
  10. Kalashnikov M, Choi W, Yu CC, Sung Y, Dasari RR, Badizadegan K, Feld MS. Assessing light scattering of intracellular organelles in single intact living cells. Opt Express. 2009 Oct 26; 17(22):19674-81.
    View in: PubMed
  11. Park Y, Choi W, Yaqoob Z, Dasari R, Badizadegan K, Feld MS. Speckle-field digital holographic microscopy. Opt Express. 2009 Jul 20; 17(15):12285-92.
    View in: PubMed
  12. Mirkovic J, Lau C, McGee S, Yu CC, Nazemi J, Galindo L, Feng V, Darragh T, de Las Morenas A, Crum C, Stier E, Feld M, Badizadegan K. Effect of anatomy on spectroscopic detection of cervical dysplasia. J Biomed Opt. 2009 Jul-Aug; 14(4):044021.
    View in: PubMed
  13. Yaqoob Z, Choi W, Oh S, Lue N, Park Y, Fang-Yen C, Dasari RR, Badizadegan K, Feld MS. Improved phase sensitivity in spectral domain phase microscopy using line-field illumination and self phase-referencing. Opt Express. 2009 Jun 22; 17(13):10681-7.
    View in: PubMed
  14. Sung Y, Choi W, Fang-Yen C, Badizadegan K, Dasari RR, Feld MS. Optical diffraction tomography for high resolution live cell imaging. Opt Express. 2009 Jan 5; 17(1):266-77.
    View in: PubMed
  15. McGee S, Mirkovic J, Mardirossian V, Elackattu A, Yu CC, Kabani S, Gallagher G, Pistey R, Galindo L, Badizadegan K, Wang Z, Dasari R, Feld MS, Grillone G. Model-based spectroscopic analysis of the oral cavity: impact of anatomy. J Biomed Opt. 2008 Nov-Dec; 13(6):064034.
    View in: PubMed
  16. Yu CC, Lau C, O'Donoghue G, Mirkovic J, McGee S, Galindo L, Elackattu A, Stier E, Grillone G, Badizadegan K, Dasari RR, Feld MS. Quantitative spectroscopic imaging for non-invasive early cancer detection. Opt Express. 2008 Sep 29; 16(20):16227-39.
    View in: PubMed
  17. Lue N, Choi W, Popescu G, Badizadegan K, Dasari RR, Feld MS. Synthetic aperture tomographic phase microscopy for 3D imaging of live cells in translational motion. Opt Express. 2008 Sep 29; 16(20):16240-6.
    View in: PubMed
  18. Lue N, Choi W, Badizadegan K, Dasari RR, Feld MS, Popescu G. Confocal diffraction phase microscopy of live cells. Opt Lett. 2008 Sep 15; 33(18):2074-6.
    View in: PubMed
  19. Choi W, Yu CC, Fang-Yen C, Badizadegan K, Dasari RR, Feld MS. Field-based angle-resolved light-scattering study of single live cells. Opt Lett. 2008 Jul 15; 33(14):1596-8.
    View in: PubMed
  20. Popescu G, Park Y, Lue N, Best-Popescu C, Deflores L, Dasari RR, Feld MS, Badizadegan K. Optical imaging of cell mass and growth dynamics. Am J Physiol Cell Physiol. 2008 Aug; 295(2):C538-44.
    View in: PubMed
  21. Popescu G, Park Y, Choi W, Dasari RR, Feld MS, Badizadegan K. Imaging red blood cell dynamics by quantitative phase microscopy. Blood Cells Mol Dis. 2008 Jul-Aug; 41(1):10-6.
    View in: PubMed
  22. Choi W, Fang-Yen C, Badizadegan K, Dasari RR, Feld MS. Extended depth of focus in tomographic phase microscopy using a propagation algorithm. Opt Lett. 2008 Jan 15; 33(2):171-3.
    View in: PubMed
  23. Lue N, Bewersdorf J, Lessard MD, Badizadegan K, Dasari RR, Feld MS, Popescu G. Tissue refractometry using Hilbert phase microscopy. Opt Lett. 2007 Dec 15; 32(24):3522-4.
    View in: PubMed
  24. Amin MS, Park Y, Lue N, Dasari RR, Badizadegan K, Feld MS, Popescu G. Microrheology of red blood cell membranes using dynamic scattering microscopy. Opt Express. 2007 Dec 10; 15(25):17001-9.
    View in: PubMed
  25. Popescu G, Park Y, Dasari RR, Badizadegan K, Feld MS. Coherence properties of red blood cell membrane motions. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Sep; 76(3 Pt 1):031902.
    View in: PubMed
  26. Choi W, Fang-Yen C, Badizadegan K, Oh S, Lue N, Dasari RR, Feld MS. Tomographic phase microscopy. Nat Methods. 2007 Sep; 4(9):717-9.
    View in: PubMed
  27. Park Y, Popescu G, Badizadegan K, Dasari RR, Feld MS. Fresnel particle tracing in three dimensions using diffraction phase microscopy. Opt Lett. 2007 Apr 1; 32(7):811-3.
    View in: PubMed
  28. Lue N, Choi W, Popescu G, Ikeda T, Dasari RR, Badizadegan K, Feld MS. Quantitative phase imaging of live cells using fast Fourier phase microscopy. Appl Opt. 2007 Apr 1; 46(10):1836-42.
    View in: PubMed
  29. Popescu G, Ikeda T, Goda K, Best-Popescu CA, Laposata M, Manley S, Dasari RR, Badizadegan K, Feld MS. Optical measurement of cell membrane tension. Phys Rev Lett. 2006 Nov 24; 97(21):218101.
    View in: PubMed
  30. Yu CC, Lau C, Tunnell JW, Hunter M, Kalashnikov M, Fang-Yen C, Fulghum SF, Badizadegan K, Dasari RR, Feld MS. Assessing epithelial cell nuclear morphology by using azimuthal light scattering spectroscopy. Opt Lett. 2006 Nov 1; 31(21):3119-21.
    View in: PubMed
  31. Hunter M, Backman V, Popescu G, Kalashnikov M, Boone CW, Wax A, Gopal V, Badizadegan K, Stoner GD, Feld MS. Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection. Phys Rev Lett. 2006 Sep 29; 97(13):138102.
    View in: PubMed
  32. Lue N, Popescu G, Ikeda T, Dasari RR, Badizadegan K, Feld MS. Live cell refractometry using microfluidic devices. Opt Lett. 2006 Sep 15; 31(18):2759-61.
    View in: PubMed
  33. Park Y, Popescu G, Badizadegan K, Dasari RR, Feld MS. Diffraction phase and fluorescence microscopy. Opt Express. 2006 Sep 4; 14(18):8263-8.
    View in: PubMed
  34. Popescu G, Badizadegan K, Dasari RR, Feld MS. Observation of dynamic subdomains in red blood cells. J Biomed Opt. 2006 Jul-Aug; 11(4):040503.
    View in: PubMed
  35. Kradin RL, Badizadegan K, Auluck P, Korzenik J, Lauwers GY. Iatrogenic Trichuris suis infection in a patient with Crohn disease. Arch Pathol Lab Med. 2006 May; 130(5):718-20.
    View in: PubMed
  36. Popescu G, Ikeda T, Best CA, Badizadegan K, Dasari RR, Feld MS. Erythrocyte structure and dynamics quantified by Hilbert phase microscopy. J Biomed Opt. 2005 Nov-Dec; 10(6):060503.
    View in: PubMed
  37. Korzenik J, Chung DC, Digumarthy S, Badizadegan K. Case records of the Massachusetts General Hospital. Case 33-2005. A 43-year-old man with lower gastrointestinal bleeding. N Engl J Med. 2005 Oct 27; 353(17):1836-44.
    View in: PubMed
  38. Andrews NC, Anupindi S, Badizadegan K. Case records of the Massachusetts General Hospital. Case 21-2005. A four-week-old male infant with jaundice and thrombocytopenia. N Engl J Med. 2005 Jul 14; 353(2):189-98.
    View in: PubMed
  39. Desai TK, Stecevic V, Chang CH, Goldstein NS, Badizadegan K, Furuta GT. Association of eosinophilic inflammation with esophageal food impaction in adults. Gastrointest Endosc. 2005 Jun; 61(7):795-801.
    View in: PubMed
  40. Ahn A, Yang C, Wax A, Popescu G, Fang-Yen C, Badizadegan K, Dasari RR, Feld MS. Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer. Appl Opt. 2005 Mar 1; 44(7):1188-90.
    View in: PubMed
  41. Popescu G, Deflores LP, Vaughan JC, Badizadegan K, Iwai H, Dasari RR, Feld MS. Fourier phase microscopy for investigation of biological structures and dynamics. Opt Lett. 2004 Nov 1; 29(21):2503-5.
    View in: PubMed
  42. Iwai H, Fang-Yen C, Popescu G, Wax A, Badizadegan K, Dasari RR, Feld MS. Quantitative phase imaging using actively stabilized phase-shifting low-coherence interferometry. Opt Lett. 2004 Oct 15; 29(20):2399-401.
    View in: PubMed
  43. Fogt F, Brown CA, Badizadegan K, Zimmerman RL, Odze R. Low prevalence of loss of heterozygosity and SMAD4 mutations in sporadic and familial juvenile polyposis syndrome-associated juvenile polyps. Am J Gastroenterol. 2004 Oct; 99(10):2025-31.
    View in: PubMed
  44. Badizadegan K, Wheeler HE, Fujinaga Y, Lencer WI. Trafficking of cholera toxin-ganglioside GM1 complex into Golgi and induction of toxicity depend on actin cytoskeleton. Am J Physiol Cell Physiol. 2004 Nov; 287(5):C1453-62.
    View in: PubMed
  45. Badizadegan K. Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis. Gastroenterology. 2004 May; 126(5):1493; author reply 1494-5.
    View in: PubMed
  46. Nurko S, Teitelbaum JE, Husain K, Buonomo C, Fox VL, Antonioli D, Fortunato C, Badizadegan K, Furuta GT. Association of Schatzki ring with eosinophilic esophagitis in children. J Pediatr Gastroenterol Nutr. 2004 Apr; 38(4):436-41.
    View in: PubMed
  47. Badizadegan K, Backman V, Boone CW, Crum CP, Dasari RR, Georgakoudi I, Keefe K, Munger K, Shapshay SM, Sheetse EE, Feld MS. Spectroscopic diagnosis and imaging of invisible pre-cancer. Faraday Discuss. 2004; 126:265-79; discussion 303-11.
    View in: PubMed
  48. Fox VL, Nurko S, Teitelbaum JE, Badizadegan K, Furuta GT. High-resolution EUS in children with eosinophilic "allergic" esophagitis. Gastrointest Endosc. 2003 Jan; 57(1):30-6.
    View in: PubMed
  49. Teitelbaum JE, Fox VL, Twarog FJ, Nurko S, Antonioli D, Gleich G, Badizadegan K, Furuta GT. Eosinophilic esophagitis in children: immunopathological analysis and response to fluticasone propionate. Gastroenterology. 2002 May; 122(5):1216-25.
    View in: PubMed
  50. Wax A, Yang C, Backman V, Badizadegan K, Boone CW, Dasari RR, Feld MS. Cellular organization and substructure measured using angle-resolved low-coherence interferometry. Biophys J. 2002 Apr; 82(4):2256-64.
    View in: PubMed
  51. Georgakoudi I, Sheets EE, Müller MG, Backman V, Crum CP, Badizadegan K, Dasari RR, Feld MS. Trimodal spectroscopy for the detection and characterization of cervical precancers in vivo. Am J Obstet Gynecol. 2002 Mar; 186(3):374-82.
    View in: PubMed
  52. Georgakoudi I, Jacobson BC, Müller MG, Sheets EE, Badizadegan K, Carr-Locke DL, Crum CP, Boone CW, Dasari RR, Van Dam J, Feld MS. NAD(P)H and collagen as in vivo quantitative fluorescent biomarkers of epithelial precancerous changes. Cancer Res. 2002 Feb 1; 62(3):682-7.
    View in: PubMed
  53. Gurjar RS, Backman V, Perelman LT, Georgakoudi I, Badizadegan K, Itzkan I, Dasari RR, Feld MS. Imaging human epithelial properties with polarized light-scattering spectroscopy. Nat Med. 2001 Nov; 7(11):1245-8.
    View in: PubMed
  54. Yang C, Wax A, Hahn MS, Badizadegan K, Dasari RR, Feld MS. Phase-referenced interferometer with subwavelength and subhertz sensitivity applied to the study of cell membrane dynamics. Opt Lett. 2001 Aug 15; 26(16):1271-3.
    View in: PubMed
  55. Georgakoudi I, Jacobson BC, Van Dam J, Backman V, Wallace MB, Müller MG, Zhang Q, Badizadegan K, Sun D, Thomas GA, Perelman LT, Feld MS. Fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in patients with Barrett's esophagus. Gastroenterology. 2001 Jun; 120(7):1620-9.
    View in: PubMed
  56. Furuta GT, Nurko S, Bousvaros A, Antonioli D, Badizadegan K. The spectrum of pediatric gastroesophageal reflux. JAMA. 2000 Dec 27; 284(24):3125-6.
    View in: PubMed
  57. Yang C, Wax A, Georgakoudi I, Hanlon EB, Badizadegan K, Dasari RR, Feld MS. Interferometric phase-dispersion microscopy. Opt Lett. 2000 Oct 15; 25(20):1526-8.
    View in: PubMed
  58. Badizadegan K, Wolf AA, Rodighiero C, Jobling M, Hirst TR, Holmes RK, Lencer WI. Floating cholera toxin into epithelial cells: functional association with caveolae-like detergent-insoluble membrane microdomains. Int J Med Microbiol. 2000 Oct; 290(4-5):403-8.
    View in: PubMed
  59. Wallace MB, Perelman LT, Backman V, Crawford JM, Fitzmaurice M, Seiler M, Badizadegan K, Shields SJ, Itzkan I, Dasari RR, Van Dam J, Feld MS. Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy. Gastroenterology. 2000 Sep; 119(3):677-82.
    View in: PubMed
  60. Backman V, Wallace MB, Perelman LT, Arendt JT, Gurjar R, Müller MG, Zhang Q, Zonios G, Kline E, McGilligan JA, Shapshay S, Valdez T, Badizadegan K, Crawford JM, Fitzmaurice M, Kabani S, Levin HS, Seiler M, Dasari RR, Itzkan I, Van Dam J, Feld MS, McGillican T. Detection of preinvasive cancer cells. Nature. 2000 Jul 6; 406(6791):35-6.
    View in: PubMed
  61. Badizadegan K, Dickinson BL, Wheeler HE, Blumberg RS, Holmes RK, Lencer WI. Heterogeneity of detergent-insoluble membranes from human intestine containing caveolin-1 and ganglioside G(M1). Am J Physiol Gastrointest Liver Physiol. 2000 Jun; 278(6):G895-904.
    View in: PubMed
  62. Dickinson BL, Badizadegan K, Wu Z, Ahouse JC, Zhu X, Simister NE, Blumberg RS, Lencer WI. Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line. J Clin Invest. 1999 Oct; 104(7):903-11.
    View in: PubMed
  63. Willett CG, Badizadegan K, Ancukiewicz M, Shellito PC. Prognostic factors in stage T3N0 rectal cancer: do all patients require postoperative pelvic irradiation and chemotherapy? Dis Colon Rectum. 1999 Feb; 42(2):167-73.
    View in: PubMed
  64. Badizadegan K, Jonas MM, Ott MJ, Nelson SP, Perez-Atayde AR. Histopathology of the liver in children with chronic hepatitis C viral infection. Hepatology. 1998 Nov; 28(5):1416-23.
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  65. Granter SR, Badizadegan K, Fletcher CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: a spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol. 1998 May; 22(5):513-25.
    View in: PubMed
  66. Jonas MM, Ott MJ, Nelson SP, Badizadegan K, Perez-Atayde AR. Interferon-alpha treatment of chronic hepatitis C virus infection in children. Pediatr Infect Dis J. 1998 Mar; 17(3):241-6.
    View in: PubMed
  67. Badizadegan K, Perez-Atayde AR. Focal glycogenosis of the liver in disorders of ureagenesis: its occurrence and diagnostic significance. Hepatology. 1997 Aug; 26(2):365-73.
    View in: PubMed
  68. Badizadegan K, Perez-Atayde AR. Pathology of lung allografts in children and young adults. Hum Pathol. 1997 Jun; 28(6):704-13.
    View in: PubMed
  69. Badizadegan K, Thompson KM. Correction to statements about lead in infant formula. N Engl J Med. 1992 Oct 15; 327(16):1178.
    View in: PubMed
  70. Badizadegan K, Thompson KM. Lead in infant formula. N Engl J Med. 1992 May 14; 326(20):1361-2.
    View in: PubMed
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