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Alexander M. Walker, D.P.H., M.D.

TitleAdjunct Professor of Epidemiology
InstitutionHarvard School of Public Health
DepartmentEpidemiology
AddressHarvard School of Public Health
Kresge Bldg, Rm 0908, Epidemiology
677 Huntington Ave
Boston MA 02115
Phone617/432-4565

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Seeger JD, Quinn S, Earnest DL, Lembo A, Kuo B, Rivero E, Walker AM. The Zelnorm epidemiologic study (ZEST): a cohort study evaluating incidence of abdominal and pelvic surgery related to tegaserod treatment. BMC Gastroenterol. 2012; 12:171.
    View in: PubMed
  2. Brookhart MA, Walker AM, Lu Y, Polakowski L, Li J, Paeglow C, Puenpatom T, Izurieta H, Daniel GW. Characterizing Vaccine-associated Risks Using Cubic Smoothing Splines. Am J Epidemiol. 2012 Nov 15; 176(10):949-57.
    View in: PubMed
  3. Velentgas P, Amato AA, Bohn RL, Arnold Chan K, Cochrane T, Funch DP, Dashevsky I, Duddy AL, Gladowski P, Greenberg SA, Kramer JM, McMahill-Walraven C, Nakasato C, Spettell CM, Syat BL, Wahl PM, Walker AM, Zhang F, Brown JS, Platt R. Risk of Guillain-Barré syndrome after meningococcal conjugate vaccination. Pharmacoepidemiol Drug Saf. 2012 Dec; 21(12):1350-8.
    View in: PubMed
  4. Walker AM, Maxim LD, Utell MJ. Are airborne refractory ceramic fibers similar to asbestos in their carcinogenicity? Inhal Toxicol. 2012 Jun; 24(7):416-24.
    View in: PubMed
  5. Gagne JJ, Rassen JA, Walker AM, Glynn RJ, Schneeweiss S. Active safety monitoring of new medical products using electronic healthcare data: selecting alerting rules. Epidemiology. 2012 Mar; 23(2):238-46.
    View in: PubMed
  6. Gagne JJ, Walker AM, Glynn RJ, Rassen JA, Schneeweiss S. An event-based approach for comparing the performance of methods for prospective medical product monitoring. Pharmacoepidemiol Drug Saf. 2012 Jun; 21(6):631-9.
    View in: PubMed
  7. Walker AM. Identification of esophageal cancer in the General Practice Research Database. Pharmacoepidemiol Drug Saf. 2011 Nov; 20(11):1159-67.
    View in: PubMed
  8. Ziyadeh N, Fife D, Walker AM, Wilkinson GS, Seeger JD. A matched cohort study of the risk of cancer in users of becaplermin. Adv Skin Wound Care. 2011 Jan; 24(1):31-9.
    View in: PubMed
  9. Walker AM. Orthogonal predictions: follow-up questions for suggestive data. Pharmacoepidemiol Drug Saf. 2010 May; 19(5):529-32.
    View in: PubMed
  10. Walker AM. Signal detection for vaccine side effects that have not been specified in advance. Pharmacoepidemiol Drug Saf. 2010 Mar; 19(3):311-7.
    View in: PubMed
  11. Brown JS, Moore KM, Braun MM, Ziyadeh N, Chan KA, Lee GM, Kulldorff M, Walker AM, Platt R. Active influenza vaccine safety surveillance: potential within a healthcare claims environment. Med Care. 2009 Dec; 47(12):1251-7.
    View in: PubMed
  12. Kurth T, Lewis BE, Walker AM. Health care resource utilization in patients with active epilepsy. Epilepsia. 2010 May; 51(5):874-82.
    View in: PubMed
  13. Velentgas P, Bohn RL, Brown JS, Chan KA, Gladowski P, Holick CN, Kramer JM, Nakasato C, Spettell CM, Walker AM, Zhang F, Platt R. A distributed research network model for post-marketing safety studies: the Meningococcal Vaccine Study. Pharmacoepidemiol Drug Saf. 2008 Dec; 17(12):1226-34.
    View in: PubMed
  14. Patterson MK, Castellsague J, Walker AM. Hospitalization for peptic ulcer and bleeding in users of selective COX-2 inhibitors and nonselective NSAIDs with special reference to celecoxib. Pharmacoepidemiol Drug Saf. 2008 Oct; 17(10):982-8.
    View in: PubMed
  15. Loughlin J, Seeger JD, Eng PM, Foegh M, Clifford CR, Cutone J, Walker AM. Risk of hyperkalemia in women taking ethinylestradiol/drospirenone and other oral contraceptives. Contraception. 2008 Nov; 78(5):377-83.
    View in: PubMed
  16. Walker AM, Koro CE, Landon J. Coronary heart disease outcomes in patients receiving antidiabetic agents in the PharMetrics database 2000-2007. Pharmacoepidemiol Drug Saf. 2008 Aug; 17(8):760-8.
    View in: PubMed
  17. Walker AM, Bennett D. Epidemiology and outcomes in patients with atrial fibrillation in the United States. Heart Rhythm. 2008 Oct; 5(10):1365-72.
    View in: PubMed
  18. Schneeweiss S, Walker AM, Seeger JD. Effect of aprotinin on renal dysfunction. Lancet. 2008 Jul 5; 372(9632):26; author reply 26-7.
    View in: PubMed
  19. McAfee AT, Holdridge KC, Johannes CB, Hornbuckle K, Walker AM. The effect of pharmacotherapy for attention deficit hyperactivity disorder on risk of seizures in pediatric patients as assessed in an insurance claims database. Curr Drug Saf. 2008 May; 3(2):123-31.
    View in: PubMed
  20. Eng PM, Seeger JD, Loughlin J, Clifford CR, Mentor S, Walker AM. Supplementary data collection with case-cohort analysis to address potential confounding in a cohort study of thromboembolism in oral contraceptive initiators matched on claims-based propensity scores. Pharmacoepidemiol Drug Saf. 2008 Mar; 17(3):297-305.
    View in: PubMed
  21. Schneeweiss S, Seeger JD, Landon J, Walker AM. Aprotinin during coronary-artery bypass grafting and risk of death. N Engl J Med. 2008 Feb 21; 358(8):771-83.
    View in: PubMed
  22. Walker AM, McAfee AT, Koro C. Studies of diabetes, thiazolidinediones, and coronary heart disease. Pharmacoepidemiol Drug Saf. 2007 Dec; 16(12):1313-4; author reply 1314-6.
    View in: PubMed
  23. Seeger JD, Kurth T, Walker AM. Use of propensity score technique to account for exposure-related covariates: an example and lesson. Med Care. 2007 Oct; 45(10 Supl 2):S143-8.
    View in: PubMed
  24. Cole JA, Ephross SA, Cosmatos IS, Walker AM. Paroxetine in the first trimester and the prevalence of congenital malformations. Pharmacoepidemiol Drug Saf. 2007 Oct; 16(10):1075-85.
    View in: PubMed
  25. Seeger JD, Loughlin J, Eng PM, Clifford CR, Cutone J, Walker AM. Risk of thromboembolism in women taking ethinylestradiol/drospirenone and other oral contraceptives. Obstet Gynecol. 2007 Sep; 110(3):587-93.
    View in: PubMed
  26. Marc LG, Testa MA, Walker AM, Robbins GK, Shafer RW, Anderson NB, Berkman LF. Educational attainment and response to HAART during initial therapy for HIV-1 infection. J Psychosom Res. 2007 Aug; 63(2):207-16.
    View in: PubMed
  27. McAfee AT, Koro C, Landon J, Ziyadeh N, Walker AM. Coronary heart disease outcomes in patients receiving antidiabetic agents. Pharmacoepidemiol Drug Saf. 2007 Jul; 16(7):711-25.
    View in: PubMed
  28. Harrold LR, Patterson MK, Andrade SE, Dube T, Go AS, Buist AS, Chan KA, Weller PF, Wechsler ME, Yood RA, Davis KJ, Platt R, Walker AM. Asthma drug use and the development of Churg-Strauss syndrome (CSS). Pharmacoepidemiol Drug Saf. 2007 Jun; 16(6):620-6.
    View in: PubMed
  29. Cole JA, Modell JG, Haight BR, Cosmatos IS, Stoler JM, Walker AM. Bupropion in pregnancy and the prevalence of congenital malformations. Pharmacoepidemiol Drug Saf. 2007 May; 16(5):474-84.
    View in: PubMed
  30. McAfee AT, Chilcott KE, Johannes CB, Hornbuckle K, Hauser WA, Walker AM. The incidence of first provoked and unprovoked seizure in pediatric patients with and without psychiatric diagnoses. Epilepsia. 2007 Jun; 48(6):1075-82.
    View in: PubMed
  31. Nordstrom BL, Norman HS, Dube TJ, Wilcox MA, Walker AM. Identification of abacavir hypersensitivity reaction in health care claims data. Pharmacoepidemiol Drug Saf. 2007 Mar; 16(3):289-96.
    View in: PubMed
  32. Kurth T, Heuschmann PU, Walker AM, Berger K. Mortality of stroke patients treated with thrombolysis: analysis of nationwide inpatient sample. Neurology. 2007 Feb 27; 68(9):710; author reply 711.
    View in: PubMed
  33. Cole JA, Norman H, Doherty M, Walker AM. Venous thromboembolism, myocardial infarction, and stroke among transdermal contraceptive system users. Obstet Gynecol. 2007 Feb; 109(2 Pt 1):339-46.
    View in: PubMed
  34. Seeger JD, West WA, Fife D, Noel GJ, Johnson LN, Walker AM. Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population. Pharmacoepidemiol Drug Saf. 2006 Nov; 15(11):784-92.
    View in: PubMed
  35. Mona Eng P, Seeger JD, Loughlin J, Oh K, Walker AM. Serum potassium monitoring for users of ethinyl estradiol/drospirenone taking medications predisposing to hyperkalemia: physician compliance and survey of knowledge and attitudes. Contraception. 2007 Feb; 75(2):101-7.
    View in: PubMed
  36. Velentgas P, West W, Cannuscio CC, Watson DJ, Walker AM. Cardiovascular risk of selective cyclooxygenase-2 inhibitors and other non-aspirin non-steroidal anti-inflammatory medications. Pharmacoepidemiol Drug Saf. 2006 Sep; 15(9):641-52.
    View in: PubMed
  37. Walker AM, Langleben D, Korelitz JJ, Rich S, Rubin LJ, Strom BL, Gonin R, Keast S, Badesch D, Barst RJ, Bourge RC, Channick R, Frost A, Gaine S, McGoon M, McLaughlin V, Murali S, Oudiz RJ, Robbins IM, Tapson V, Abenhaim L, Constantine G. Temporal trends and drug exposures in pulmonary hypertension: an American experience. Am Heart J. 2006 Sep; 152(3):521-6.
    View in: PubMed
  38. Cole JA, Norman H, Weatherby LB, Walker AM. Drug copayment and adherence in chronic heart failure: effect on cost and outcomes. Pharmacotherapy. 2006 Aug; 26(8):1157-64.
    View in: PubMed
  39. Walker AM, Schneider G, Yeaw J, Nordstrom B, Robbins S, Pettitt D. Anemia as a predictor of cardiovascular events in patients with elevated serum creatinine. J Am Soc Nephrol. 2006 Aug; 17(8):2293-8.
    View in: PubMed
  40. McAfee AT, Ming EE, Seeger JD, Quinn SG, Ng EW, Danielson JD, Cutone JA, Fox JC, Walker AM. The comparative safety of rosuvastatin: a retrospective matched cohort study in over 48,000 initiators of statin therapy. Pharmacoepidemiol Drug Saf. 2006 Jul; 15(7):444-53.
    View in: PubMed
  41. Johansson S, Ming EE, Wallander MA, Rodríguez LA, Herings RM, Goettsch WG, González-Pérez A, McAfee AT, Walker AM. Rosuvastatin safety: a comprehensive, international pharmacoepidemiology programme. Pharmacoepidemiol Drug Saf. 2006 Jul; 15(7):454-61.
    View in: PubMed
  42. Walker AM. More lawyers. More bureaucrats. Less information on drug safety. Pharmacoepidemiol Drug Saf. 2006 Jun; 15(6):394-5.
    View in: PubMed
  43. Sands BE, Duh MS, Cali C, Ajene A, Bohn RL, Miller D, Cole JA, Cook SF, Walker AM. Algorithms to identify colonic ischemia, complications of constipation and irritable bowel syndrome in medical claims data: development and validation. Pharmacoepidemiol Drug Saf. 2006 Jan; 15(1):47-56.
    View in: PubMed
  44. Kurth T, Walker AM, Glynn RJ, Chan KA, Gaziano JM, Berger K, Robins JM. Results of multivariable logistic regression, propensity matching, propensity adjustment, and propensity-based weighting under conditions of nonuniform effect. Am J Epidemiol. 2006 Feb 1; 163(3):262-70.
    View in: PubMed
  45. Cole JA, Yeaw JM, Cutone JA, Kuo B, Huang Z, Earnest DL, Walker AM. The incidence of abdominal and pelvic surgery among patients with irritable bowel syndrome. Dig Dis Sci. 2005 Dec; 50(12):2268-75.
    View in: PubMed
  46. Caspard H, Chan AK, Walker AM. Determinants of the differences in LDL-cholesterol after initiation of statin treatment. Ann Pharmacother. 2006 Jan; 40(1):21-6.
    View in: PubMed
  47. Funch DP, Ko HH, Travasso J, Brady J, Kew CE, Nalesnik MA, Walker AM. Posttransplant lymphoproliferative disorder among renal transplant patients in relation to the use of mycophenolate mofetil. Transplantation. 2005 Nov 15; 80(9):1174-80.
    View in: PubMed
  48. Nordstrom BL, Friedman DS, Mozaffari E, Quigley HA, Walker AM. Persistence and adherence with topical glaucoma therapy. Am J Ophthalmol. 2005 Oct; 140(4):598-606.
    View in: PubMed
  49. Caspard H, Chan AK, Walker AM. The long-term course of low-density lipoprotein cholesterol after initiation of statin treatment: retrospective database analysis over 3 years in health maintenance organization enrollees. Clin Ther. 2005 Oct; 27(10):1622-8.
    View in: PubMed
  50. Caspard H, Chan AK, Walker AM. Compliance with a statin treatment in a usual-care setting: retrospective database analysis over 3 years after treatment initiation in health maintenance organization enrollees with dyslipidemia. Clin Ther. 2005 Oct; 27(10):1639-46.
    View in: PubMed
  51. Seeger JD, Williams PL, Walker AM. An application of propensity score matching using claims data. Pharmacoepidemiol Drug Saf. 2005 Jul; 14(7):465-76.
    View in: PubMed
  52. Wagner AK, Zhang F, Soumerai SB, Walker AM, Gurwitz JH, Glynn RJ, Ross-Degnan D. Benzodiazepine use and hip fractures in the elderly: who is at greatest risk? Arch Intern Med. 2004 Jul 26; 164(14):1567-72.
    View in: PubMed
  53. Velentgas P, Cole JA, Mo J, Sikes CR, Walker AM. Severe vascular events in migraine patients. Headache. 2004 Jul-Aug; 44(7):642-51.
    View in: PubMed
  54. Walker AM, Bohn RL, Cali C, Cook SF, Ajene AN, Sands BE. Risk factors for colon ischemia. Am J Gastroenterol. 2004 Jul; 99(7):1333-7.
    View in: PubMed
  55. Miller DP, Kaye JA, Shea K, Ziyadeh N, Cali C, Black C, Walker AM. Incidence of thrombotic thrombocytopenic purpura/hemolytic uremic syndrome. Epidemiology. 2004 Mar; 15(2):208-15.
    View in: PubMed
  56. Cole JA, Cook SF, Sands BE, Ajene AN, Miller DP, Walker AM. Occurrence of colon ischemia in relation to irritable bowel syndrome. Am J Gastroenterol. 2004 Mar; 99(3):486-91.
    View in: PubMed
  57. Enger C, Weatherby L, Reynolds RF, Glasser DB, Walker AM. Serious cardiovascular events and mortality among patients with schizophrenia. J Nerv Ment Dis. 2004 Jan; 192(1):19-27.
    View in: PubMed
  58. Laden F, Stampfer MJ, Walker AM. Lung cancer and mesothelioma among male automobile mechanics: a review. Rev Environ Health. 2004 Jan-Mar; 19(1):39-61.
    View in: PubMed
  59. Walker AM. Epidemiology: quo statis? Eur J Epidemiol. 2004; 19(8):723-4.
    View in: PubMed
  60. Seeger JD, Walker AM, Williams PL, Saperia GM, Sacks FM. A propensity score-matched cohort study of the effect of statins, mainly fluvastatin, on the occurrence of acute myocardial infarction. Am J Cardiol. 2003 Dec 15; 92(12):1447-51.
    View in: PubMed
  61. Bisson G, Gross R, Miller V, Weller I, Walker A, Arlett P, Carr A, Evans S, Graham D, Justice A, Kreft-Jais C, Lundgren JD, Munk B, Murray J, Pirmohamed M, Pizzuti D, Szarfman A. Monitoring of long-term toxicities of HIV treatments: an international perspective. AIDS. 2003 Nov 21; 17(17):2407-17.
    View in: PubMed
  62. Schneeweiss S, Soumerai SB, Maclure M, Dormuth C, Walker AM, Glynn RJ. Clinical and economic consequences of reference pricing for dihydropyridine calcium channel blockers. Clin Pharmacol Ther. 2003 Oct; 74(4):388-400.
    View in: PubMed
  63. Kurth T, Glynn RJ, Walker AM, Chan KA, Buring JE, Hennekens CH, Gaziano JM. Inhibition of clinical benefits of aspirin on first myocardial infarction by nonsteroidal antiinflammatory drugs. Circulation. 2003 Sep 9; 108(10):1191-5.
    View in: PubMed
  64. Kurth T, Glynn RJ, Walker AM, Rexrode KM, Buring JE, Stampfer MJ, Hennekens CH, Gaziano JM. Analgesic use and change in kidney function in apparently healthy men. Am J Kidney Dis. 2003 Aug; 42(2):234-44.
    View in: PubMed
  65. Miller DP, Alfredson T, Cook SF, Sands BE, Walker AM. Incidence of colonic ischemia, hospitalized complications of constipation, and bowel surgery in relation to use of alosetron hydrochloride. Am J Gastroenterol. 2003 May; 98(5):1117-22.
    View in: PubMed
  66. Wang PS, Walker AM, Tsuang MT, Orav EJ, Glynn RJ, Levin R, Avorn J. Dopamine antagonists and the development of breast cancer. Arch Gen Psychiatry. 2002 Dec; 59(12):1147-54.
    View in: PubMed
  67. Weatherby LB, Nordstrom BL, Fife D, Walker AM. The impact of wording in "Dear doctor" letters and in black box labels. Clin Pharmacol Ther. 2002 Dec; 72(6):735-42.
    View in: PubMed
  68. Reynolds RF, Obermeyer CM, Walker AM, Guilbert D. The role of treatment intentions and concerns about side effects in women's decision to discontinue postmenopausal hormone therapy. Maturitas. 2002 Nov 20; 43(3):183-94.
    View in: PubMed
  69. Loughlin JE, Alfredson TD, Ajene AN, Cole JA, Cook SE, Rosenberg DM, Walker AM. Risk for respiratory events in a cohort of patients receiving inhaled zanamivir: a retrospective study. Clin Ther. 2002 Nov; 24(11):1786-99.
    View in: PubMed
  70. Cole JA, Loughlin JE, Ajene AN, Rosenberg DM, Cook SE, Walker AM. The effect of zanamivir treatment on influenza complications: a retrospective cohort study. Clin Ther. 2002 Nov; 24(11):1824-39.
    View in: PubMed
  71. Enger C, Cali C, Walker AM. Serious ventricular arrhythmias among users of cisapride and other QT-prolonging agents in the United States. Pharmacoepidemiol Drug Saf. 2002 Sep; 11(6):477-86.
    View in: PubMed
  72. Schneeweiss S, Maclure M, Soumerai SB, Walker AM, Glynn RJ. Quasi-experimental longitudinal designs to evaluate drug benefit policy changes with low policy compliance. J Clin Epidemiol. 2002 Aug; 55(8):833-41.
    View in: PubMed
  73. Werneck GL, Costa CH, Walker AM, David JR, Wand M, Maguire JH. The urban spread of visceral leishmaniasis: clues from spatial analysis. Epidemiology. 2002 May; 13(3):364-7.
    View in: PubMed
  74. Schneeweiss S, Soumerai SB, Glynn RJ, Maclure M, Dormuth C, Walker AM. Impact of reference-based pricing for angiotensin-converting enzyme inhibitors on drug utilization. CMAJ. 2002 Mar 19; 166(6):737-45.
    View in: PubMed
  75. Schneeweiss S, Walker AM, Glynn RJ, Maclure M, Dormuth C, Soumerai SB. Outcomes of reference pricing for angiotensin-converting-enzyme inhibitors. N Engl J Med. 2002 Mar 14; 346(11):822-9.
    View in: PubMed
  76. Loughlin JE, Cole JA, Dodd SL, Schein JR, Thornhill JC, Walker AM. Comparison of resource utilization by patients treated with transdermal fentanyl and long-acting oral opioids for nonmalignant pain. Pain Med. 2002 Mar; 3(1):47-55.
    View in: PubMed
  77. Walker AM, Maxim LD, Utell M. Risk analysis for mortality from respiratory tumors in a cohort of refractory ceramic fiber workers. Regul Toxicol Pharmacol. 2002 Feb; 35(1):95-104.
    View in: PubMed
  78. Funch DP, Brady J, Ko HH, Dreyer NA, Walker AM. Methods and objectives of a large US multicenter case-control study of post-transplant lymphoproliferative disorder in renal transplant patients. Recent Results Cancer Res. 2002; 159:81-8.
    View in: PubMed
  79. Walker AM, Wise RP. Precautions for proactive surveillance. Pharmacoepidemiol Drug Saf. 2002 Jan-Feb; 11(1):17-20.
    View in: PubMed
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