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Keywords
Last Name
Institution

Louis Pasquale, M.D.

TitleAssociate Professor of Ophthalmology
InstitutionMassachusetts Eye and Ear Infirmary
DepartmentOphthalmology
AddressMassachusetts Eye & Ear Infrm
Ophthalmology
243 Charles St
Boston MA 02114
Phone617/573-3674
Fax617/573-3707

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Liu Y, Hauser MA, Akafo SK, Qin X, Miura S, Gibson JR, Wheeler J, Gaasterland DE, Challa P, Herndon LW, Ritch R, Moroi SE, Pasquale LR, Girkin CA, Budenz DL, Wiggs JL, Richards JE, Ashley-Koch AE, Allingham RR. Investigation of known genetic risk factors for primary open angle glaucoma in two populations of african ancestry. Invest Ophthalmol Vis Sci. 2013; 54(9):6248-54.
    View in: PubMed
  2. Ozel AB, Moroi SE, Reed DM, Nika M, Schmidt CM, Akbari S, Scott K, Rozsa F, Pawar H, Musch DC, Lichter PR, Gaasterland D, Branham K, Gilbert J, Garnai SJ, Chen W, Othman M, Heckenlively J, Swaroop A, Abecasis G, Friedman DS, Zack D, Ashley-Koch A, Ulmer M, Kang JH, Liu Y, Yaspan BL, Haines J, Allingham RR, Hauser MA, Pasquale L, Wiggs J, Richards JE, Li JZ. Genome-wide association study and meta-analysis of intraocular pressure. Hum Genet. 2014 Jan; 133(1):41-57.
    View in: PubMed
  3. Wiggs JL, Hauser MA, Abdrabou W, Allingham RR, Budenz DL, Delbono E, Friedman DS, Kang JH, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Loomis S, Liu Y, McCarty C, Medeiros FA, Moroi SE, Olson LM, Realini A, Richards JE, Rozsa FW, Schuman JS, Singh K, Stein JD, Vollrath D, Weinreb RN, Wollstein G, Yaspan BL, Yoneyama S, Zack D, Zhang K, Pericak-Vance M, Pasquale LR, Haines JL. The NEIGHBOR Consortium Primary Open-Angle Glaucoma Genome-wide Association Study: Rationale, Study Design, and Clinical Variables. J Glaucoma. 2013 Sep; 22(7):517-25.
    View in: PubMed
  4. Ojha P, Wiggs JL, Pasquale LR. The genetics of intraocular pressure. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):301-5.
    View in: PubMed
  5. Pasquale LR, Brusie S. The blue arc entoptic phenomenon in glaucoma (an american ophthalmological thesis). Trans Am Ophthalmol Soc. 2013 Sep; 111:46-55.
    View in: PubMed
  6. Pasquale LR, Loomis SJ, Weinreb RN, Kang JH, Yaspan BL, Bailey JC, Gaasterland D, Gaasterland T, Lee RK, Scott WK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Wiggs JL. Estrogen pathway polymorphisms in relation to primary open angle glaucoma: An analysis accounting for gender from the United States. Mol Vis. 2013; 19:1471-81.
    View in: PubMed
  7. Pasquale LR. There is more to the relation between intraocular pressure and metabolic syndrome than meets the eye: a connection to estrogen deficiency. Menopause. 2013 Jul; 20(7):719-20.
    View in: PubMed
  8. Wiggs JL, Howell GR, Linkroum K, Abdrabou W, Hodges E, Braine CE, Pasquale LR, Hannon GJ, Haines JL, John SW. Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma. Clin Genet. 2013 Aug; 84(2):167-74.
    View in: PubMed
  9. Shah M, Lee G, Lefebvre DR, Kronberg B, Loomis S, Brauner SC, Turalba A, Rhee DJ, Freitag SK, Pasquale LR. A Cross-Sectional Survey of the Association between Bilateral Topical Prostaglandin Analogue Use and Ocular Adnexal Features. PLoS One. 2013; 8(5):e61638.
    View in: PubMed
  10. Kassam F, Yogesan K, Sogbesan E, Pasquale LR, Damji KF. Teleglaucoma: improving access and efficiency for glaucoma care. Middle East Afr J Ophthalmol. 2013 Apr; 20(2):142-9.
    View in: PubMed
  11. Feke GT, Rhee DJ, Turalba AV, Pasquale LR. Effects of dorzolamide-timolol and brimonidine-timolol on retinal vascular autoregulation and ocular perfusion pressure in primary open angle glaucoma. J Ocul Pharmacol Ther. 2013 Sep; 29(7):639-45.
    View in: PubMed
  12. Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerté M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR. Soluble Guanylate Cyclase a1-Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma. PLoS One. 2013; 8(3):e60156.
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  13. Kang JH, Wiggs JL, Pasquale LR. A Nested Case Control Study of Plasma ICAM-1, E-Selectin and TNF Receptor 2 Levels, and Incident Primary Open-Angle Glaucoma. Invest Ophthalmol Vis Sci. 2013; 54(3):1797-804.
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  14. Sein J, Galor A, Sheth A, Kruh J, Pasquale LR, Karp CL. Exfoliation syndrome: new genetic and pathophysiologic insights. Curr Opin Ophthalmol. 2013 Mar; 24(2):167-74.
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  15. Chu AY, Workalemahu T, Paynter NP, Rose LM, Giulianini F, Tanaka T, Ngwa JS, Qi Q, Curhan GC, Rimm EB, Hunter DJ, Pasquale LR, Ridker PM, Hu FB, Chasman DI, Qi L. Novel locus including FGF21 is associated with dietary macronutrient intake. Hum Mol Genet. 2013 May 1; 22(9):1895-902.
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  16. Pasquale LR, Loomis SJ, Aschard H, Kang JH, Cornelis MC, Qi L, Kraft P, Hu FB. Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes. Front Genet. 2013; 4:7.
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  17. Lu Y, Vitart V, Burdon KP, Khor CC, Bykhovskaya Y, Mirshahi A, Hewitt AW, Koehn D, Hysi PG, Ramdas WD, Zeller T, Vithana EN, Cornes BK, Tay WT, Tai ES, Cheng CY, Liu J, Foo JN, Saw SM, Thorleifsson G, Stefansson K, Dimasi DP, Mills RA, Mountain J, Ang W, Hoehn R, Verhoeven VJ, Grus F, Wolfs R, Castagne R, Lackner KJ, Springelkamp H, Yang J, Jonasson F, Leung DY, Chen LJ, Tham CC, Rudan I, Vatavuk Z, Hayward C, Gibson J, Cree AJ, Macleod A, Ennis S, Polasek O, Campbell H, Wilson JF, Viswanathan AC, Fleck B, Li X, Siscovick D, Taylor KD, Rotter JI, Yazar S, Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Haines JL, Kang JH, Pasquale LR, Allingham RR, Ashley-Koch A, Mitchell P, Wang JJ, Wright AF, Pennell C, Spector TD, Young TL, Klaver CC, Martin NG, Montgomery GW, Anderson MG, Aung T, Willoughby CE, Wiggs JL, Pang CP, Thorsteinsdottir U, Lotery AJ, Hammond CJ, van Duijn CM, Hauser MA, Rabinowitz YS, Pfeiffer N, Mackey DA, Craig JE, Macgregor S, Wong TY. Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet. 2013 Feb; 45(2):155-63.
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  18. Wiecek E, Pasquale LR, Fiser J, Dakin S, Bex PJ. Effects of peripheral visual field loss on eye movements during visual search. Front Psychol. 2012; 3:472.
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  19. Pasquale LR, Loomis SJ, Kang JH, Yaspan BL, Abdrabou W, Budenz DL, Chen TC, Delbono E, Friedman DS, Gaasterland D, Gaasterland T, Grosskreutz CL, Lee RK, Lichter PR, Liu Y, McCarty CA, Moroi SE, Olson LM, Realini T, Rhee DJ, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Allingham RR, Pericak-Vance MA, Weinreb RN, Zhang K, Hauser MA, Richards JE, Haines JL, Wiggs JL. CDKN2B-AS1 Genotype-Glaucoma Feature Correlations in Primary Open-Angle Glaucoma Patients From the United States. Am J Ophthalmol. 2013 Feb; 155(2):342-353.e5.
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  20. Parver DL, Dreher RJ, Kohanim S, Zimmerman P, Garrett G, Devisetty L, Pasquale LR. Ocular injury after laser hair reduction treatment to the eyebrow. Arch Ophthalmol. 2012 Oct 1; 130(10):1330-4.
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  21. Wiggs JL, Hewitt AW, Fan BJ, Wang DY, Figueiredo Sena DR, O'Brien C, Realini A, Craig JE, Dimasi DP, Mackey DA, Haines JL, Pasquale LR. The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma. PLoS One. 2012; 7(9):e45613.
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  22. Qi Q, Chu AY, Kang JH, Jensen MK, Curhan GC, Pasquale LR, Ridker PM, Hunter DJ, Willett WC, Rimm EB, Chasman DI, Hu FB, Qi L. Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med. 2012 Oct 11; 367(15):1387-96.
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  23. Pasquale LR, Wiggs JL, Willett WC, Kang JH. The Relationship between caffeine and coffee consumption and exfoliation glaucoma or glaucoma suspect: a prospective study in two cohorts. Invest Ophthalmol Vis Sci. 2012 Sep; 53(10):6427-33.
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  24. Qi Q, Li Y, Chomistek AK, Kang JH, Curhan GC, Pasquale LR, Willett WC, Rimm EB, Hu FB, Qi L. Television watching, leisure time physical activity, and the genetic predisposition in relation to body mass index in women and men. Circulation. 2012 Oct 9; 126(15):1821-7.
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  25. Wong JJ, Chen TC, Shen LQ, Pasquale LR. Macular Imaging for Glaucoma Using Spectral-domain Optical Coherence Tomography: A Review. Semin Ophthalmol. 2012 Sep; 27(5-6):165-71.
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  26. Vajaranant TS, Pasquale LR. Estrogen deficiency accelerates aging of the optic nerve. Menopause. 2012 Aug; 19(8):942-7.
    View in: PubMed
  27. Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Hawthorne F, Budenz DL, Friedman DS, Gaasterland D, Haines J, Kang JH, Lee R, Lichter P, Liu Y, Pasquale LR, Pericak-Vance M, Realini A, Schuman JS, Singh K, Vollrath D, Weinreb R, Wollstein G, Zack DJ, Zhang K, Young T, Allingham RR, Wiggs JL, Ashley-Koch A, Hauser MA. Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. Invest Ophthalmol Vis Sci. 2012 Jul; 53(8):4468-74.
    View in: PubMed
  28. Jiwani AZ, Rhee DJ, Brauner SC, Gardiner MF, Chen TC, Shen LQ, Chen SH, Grosskreutz CL, Chang KK, Kloek CE, Greenstein SH, Borboli-Gerogiannis S, Pasquale DL, Chaudhry S, Loomis S, Wiggs JL, Pasquale LR, Turalba AV. Effects of caffeinated coffee consumption on intraocular pressure, ocular perfusion pressure, and ocular pulse amplitude: a randomized controlled trial. Eye (Lond). 2012 Aug; 26(8):1122-30.
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  29. Laurie CC, Laurie CA, Rice K, Doheny KF, Zelnick LR, McHugh CP, Ling H, Hetrick KN, Pugh EW, Amos C, Wei Q, Wang LE, Lee JE, Barnes KC, Hansel NN, Mathias R, Daley D, Beaty TH, Scott AF, Ruczinski I, Scharpf RB, Bierut LJ, Hartz SM, Landi MT, Freedman ND, Goldin LR, Ginsburg D, Li J, Desch KC, Strom SS, Blot WJ, Signorello LB, Ingles SA, Chanock SJ, Berndt SI, Le Marchand L, Henderson BE, Monroe KR, Heit JA, de Andrade M, Armasu SM, Regnier C, Lowe WL, Hayes MG, Marazita ML, Feingold E, Murray JC, Melbye M, Feenstra B, Kang JH, Wiggs JL, Jarvik GP, McDavid AN, Seshan VE, Mirel DB, Crenshaw A, Sharopova N, Wise A, Shen J, Crosslin DR, Levine DM, Zheng X, Udren JI, Bennett S, Nelson SC, Gogarten SM, Conomos MP, Heagerty P, Manolio T, Pasquale LR, Haiman CA, Caporaso N, Weir BS. Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet. 2012 Jun; 44(6):642-50.
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  30. Wiggs JL, Yaspan BL, Hauser MA, Kang JH, Allingham RR, Olson LM, Abdrabou W, Fan BJ, Wang DY, Brodeur W, Budenz DL, Caprioli J, Crenshaw A, Crooks K, Delbono E, Doheny KF, Friedman DS, Gaasterland D, Gaasterland T, Laurie C, Lee RK, Lichter PR, Loomis S, Liu Y, Medeiros FA, McCarty C, Mirel D, Moroi SE, Musch DC, Realini A, Rozsa FW, Schuman JS, Scott K, Singh K, Stein JD, Trager EH, Vanveldhuisen P, Vollrath D, Wollstein G, Yoneyama S, Zhang K, Weinreb RN, Ernst J, Kellis M, Masuda T, Zack D, Richards JE, Pericak-Vance M, Pasquale LR, Haines JL. Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. PLoS Genet. 2012; 8(4):e1002654.
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  31. Ladapo JA, Kymes SM, Ladapo JA, Nwosu VC, Pasquale LR. Projected clinical outcomes of glaucoma screening in African American individuals. Arch Ophthalmol. 2012 Mar; 130(3):365-72.
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  32. Agrawal A, Freedman ND, Cheng YC, Lin P, Shaffer JR, Sun Q, Taylor K, Yaspan B, Cole JW, Cornelis MC, DeSensi RS, Fitzpatrick A, Heiss G, Kang JH, O'Connell J, Bennett S, Bookman E, Bucholz KK, Caporaso N, Crout R, Dick DM, Edenberg HJ, Goate A, Hesselbrock V, Kittner S, Kramer J, Nurnberger JI, Qi L, Rice JP, Schuckit M, van Dam RM, Boerwinkle E, Hu F, Levy S, Marazita M, Mitchell BD, Pasquale LR, Bierut LJ. Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. Am J Clin Nutr. 2012 Mar; 95(3):539-47.
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  33. Cornelis MC, Glymour MM, Chang SC, Tchetgen EJ, Liang L, Koenen KC, Kang JH, Pasquale LR, Rimm EB, Kawachi I, Kubzansky LD. Oxytocin receptor (OXTR) is not associated with optimism in the Nurses' Health Study. Mol Psychiatry. 2012 Dec; 17(12):1157-9.
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  34. Takusagawa HL, Hunter RS, Jue A, Pasquale LR, Chen TC. Bilateral uveal effusion and angle-closure glaucoma associated with bupropion use. Arch Ophthalmol. 2012 Jan; 130(1):120-2.
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  35. Kang JH, Loomis S, Wiggs JL, Stein JD, Pasquale LR. Demographic and geographic features of exfoliation glaucoma in 2 United States-based prospective cohorts. Ophthalmology. 2012 Jan; 119(1):27-35.
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  36. Kang JH, Wiggs JL, Haines J, Abdrabou W, Pasquale LR. Reproductive factors and NOS3 variant interactions in primary open-angle glaucoma. Mol Vis. 2011; 17:2544-51.
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  37. Wiggs JL, Kang JH, Yaspan BL, Mirel DB, Laurie C, Crenshaw A, Brodeur W, Gogarten S, Olson LM, Abdrabou W, DelBono E, Loomis S, Haines JL, Pasquale LR. Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. Hum Mol Genet. 2011 Dec 1; 20(23):4707-13.
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  38. Stein JD, Pasquale LR, Talwar N, Kim DS, Reed DM, Nan B, Kang JH, Wiggs JL, Richards JE. Geographic and climatic factors associated with exfoliation syndrome. Arch Ophthalmol. 2011 Aug; 129(8):1053-60.
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  39. Kang JH, Wiggs JL, Rosner BA, Haines J, Abdrabou W, Pasquale LR. Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with hypertension, alcohol intake, and cigarette smoking. Arch Ophthalmol. 2011 Jun; 129(6):773-80.
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  40. Feke GT, Hazin R, Grosskreutz CL, Pasquale LR. Effect of brimonidine on retinal blood flow autoregulation in primary open-angle glaucoma. J Ocul Pharmacol Ther. 2011 Aug; 27(4):347-52.
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  41. Wood SD, Asefzadeh B, Fisch B, Jiwani A, Lee RK, Conlin PR, Pasquale LR. The relationship between diabetes mellitus and exfoliation syndrome in a United States Veterans Affairs population: a case-control study. J Glaucoma. 2011 Jun-Jul; 20(5):278-81.
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  42. Yang J, Manolio TA, Pasquale LR, Boerwinkle E, Caporaso N, Cunningham JM, de Andrade M, Feenstra B, Feingold E, Hayes MG, Hill WG, Landi MT, Alonso A, Lettre G, Lin P, Ling H, Lowe W, Mathias RA, Melbye M, Pugh E, Cornelis MC, Weir BS, Goddard ME, Visscher PM. Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet. 2011 Jun; 43(6):519-25.
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  43. Fan BJ, Pasquale LR, Rhee D, Li T, Haines JL, Wiggs JL. LOXL1 promoter haplotypes are associated with exfoliation syndrome in a U.S. Caucasian population. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2372-8.
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  44. Fan BJ, Wang DY, Pasquale LR, Haines JL, Wiggs JL. Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population. Invest Ophthalmol Vis Sci. 2011 Mar; 52(3):1788-92.
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  45. Pasquale LR, Kang JH. Female reproductive factors and primary open-angle glaucoma in the Nurses' Health Study. Eye (Lond). 2011 May; 25(5):633-41.
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  46. Bennett SN, Caporaso N, Fitzpatrick AL, Agrawal A, Barnes K, Boyd HA, Cornelis MC, Hansel NN, Heiss G, Heit JA, Kang JH, Kittner SJ, Kraft P, Lowe W, Marazita ML, Monroe KR, Pasquale LR, Ramos EM, van Dam RM, Udren J, Williams K. Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience. Genet Epidemiol. 2011 Apr; 35(3):159-73.
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  47. Liu Y, Takusagawa HL, Chen TC, Pasquale LR. Fuchs heterochromic iridocyclitis and the rubella virus. Int Ophthalmol Clin. 2011; 51(4):1-12.
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  48. Desronvil T, Logan-Wyatt D, Abdrabou W, Triana M, Jones R, Taheri S, Del Bono E, Pasquale LR, Olivier M, Haines JL, Fan BJ, Wiggs JL. Distribution of COL8A2 and COL8A1 gene variants in Caucasian primary open angle glaucoma patients with thin central corneal thickness. Mol Vis. 2010; 16:2185-91.
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  49. Fan BJ, Figuieredo Sena DR, Pasquale LR, Grosskreutz CL, Rhee DJ, Chen TC, Delbono EA, Haines JL, Wiggs JL. Lack of association of polymorphisms in elastin with pseudoexfoliation syndrome and glaucoma. J Glaucoma. 2010 Sep; 19(7):432-6.
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  50. Patel S, Pasquale LR. Glaucoma drainage devices: a review of the past, present, and future. Semin Ophthalmol. 2010 Sep-Nov; 25(5-6):265-70.
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  51. Loomis SJ, Olson LM, Pasquale LR, Wiggs J, Mirel D, Crenshaw A, Parkin M, Rahhal B, Tetreault S, Kraft P, Tworoger SS, Haines JL, Kang JH. Feasibility of High-Throughput Genome-Wide Genotyping using DNA from Stored Buccal Cell Samples. Biomark Insights. 2010; 5:49-55.
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  52. Cornelis MC, Agrawal A, Cole JW, Hansel NN, Barnes KC, Beaty TH, Bennett SN, Bierut LJ, Boerwinkle E, Doheny KF, Feenstra B, Feingold E, Fornage M, Haiman CA, Harris EL, Hayes MG, Heit JA, Hu FB, Kang JH, Laurie CC, Ling H, Manolio TA, Marazita ML, Mathias RA, Mirel DB, Paschall J, Pasquale LR, Pugh EW, Rice JP, Udren J, van Dam RM, Wang X, Wiggs JL, Williams K, Yu K. The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet Epidemiol. 2010 May; 34(4):364-72.
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  53. Pasquale LR, Willett WC, Rosner BA, Kang JH. Anthropometric measures and their relation to incident primary open-angle glaucoma. Ophthalmology. 2010 Aug; 117(8):1521-9.
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  54. Dohlman CH, Grosskreutz CL, Chen TC, Pasquale LR, Rubin PA, Kim EC, Durand M. Shunts to divert aqueous humor to distant epithelialized cavities after keratoprosthesis surgery. J Glaucoma. 2010 Feb; 19(2):111-5.
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  55. Pasquale LR, Walt JG, Stern LS, Wiederkehr D, Malangone E, Dolgitser M. Healthcare charges in patients with glaucoma who undergo laser trabeculoplasty. Adv Ther. 2009 Dec; 26(12):1084-96.
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  56. Pasquale LR, Walt JG, Stern LS, Wiederkehr D, Malangone E, Dolgitser M. Healthcare charges in patients who transition from ocular hypertension to primary open-angle glaucoma based on ophthalmic coding data. Adv Ther. 2009 Oct; 26(10):947-58.
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  57. Kang JH, Wiggs JL, Rosner BA, Hankinson SE, Abdrabou W, Fan BJ, Haines J, Pasquale LR. Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with sex and postmenopausal hormone use. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):971-9.
    View in: PubMed
  58. Rhee DJ, Krad O, Pasquale LR. Hyphema following selective laser trabeculoplasty. Ophthalmic Surg Lasers Imaging. 2009 Sep-Oct; 40(5):493-4.
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  59. Pasquale LR, Kang JH. Lifestyle, nutrition, and glaucoma. J Glaucoma. 2009 Aug; 18(6):423-8.
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  60. Anchala AR, Pasquale LR. Neovascular glaucoma: a historical perspective on modulating angiogenesis. Semin Ophthalmol. 2009 Mar-Apr; 24(2):106-12.
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  61. Akbari M, Akbari S, Pasquale LR. The association of primary open-angle glaucoma with mortality: a meta-analysis of observational studies. Arch Ophthalmol. 2009 Feb; 127(2):204-10.
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  62. Filippopoulos T, Hanna E, Chen TC, Grosskreutz CL, Jakobiec FA, Pasquale LR. Correlation of filtration bleb morphology with histology. Int Ophthalmol Clin. 2009; 49(1):71-82.
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  63. Fan BJ, Chen T, Grosskreutz C, Pasquale L, Rhee D, DelBono E, Haines JL, Wiggs JL. Lack of association of polymorphisms in homocysteine metabolism genes with pseudoexfoliation syndrome and glaucoma. Mol Vis. 2008; 14:2484-91.
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  64. Vavvas D, Huynh N, Pasquale L, Berson EL. Progressive hydroxychloroquine toxicity mimicking low-tension glaucoma after discontinuation of the drug. Acta Ophthalmol. 2010 Feb; 88(1):156-7.
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  65. Asefzadeh B, Pasquale LR. Detection of glaucoma-like optic discs in a diabetes teleretinal program. Optometry. 2008 Oct; 79(10):560.
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  66. Filippopoulos T, Paula JS, Torun N, Hatton MP, Pasquale LR, Grosskreutz CL. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug; 24(4):302-7.
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  67. Berisha F, Feke GT, Hirose T, McMeel JW, Pasquale LR. Retinal blood flow and nerve fiber layer measurements in early-stage open-angle glaucoma. Am J Ophthalmol. 2008 Sep; 146(3):466-472.
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  68. Pasquale LR. Low intracranial pressure: a tipping point in our understanding of primary open-angle glaucoma? Ophthalmology. 2008 May; 115(5):761-2.
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  69. Dunphy RW, Wentzolf JN, Subramanian M, Conlin PR, Pasquale LR. Structural features anterior to the retina represented in Panoramic Scanning Laser fundus images. Ophthalmic Surg Lasers Imaging. 2008 Mar-Apr; 39(2):160-3.
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  70. Kang JH, Willett WC, Rosner BA, Hankinson SE, Pasquale LR. Caffeine consumption and the risk of primary open-angle glaucoma: a prospective cohort study. Invest Ophthalmol Vis Sci. 2008 May; 49(5):1924-31.
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  71. Fan BJ, Pasquale L, Grosskreutz CL, Rhee D, Chen T, DeAngelis MM, Kim I, del Bono E, Miller JW, Li T, Haines JL, Wiggs JL. DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity. BMC Med Genet. 2008; 9:5.
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  72. Pasquale LR. Optimizing therapy for newly diagnosed open-angle glaucoma: lessons learned from the Collaborative Initial Glaucoma Treatment Study. Arch Ophthalmol. 2008 Jan; 126(1):125-7.
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  73. Pasquale LR, Asefzadeh B, Dunphy RW, Fisch BM, Conlin PR. Detection of glaucoma-like optic discs in a diabetes teleretinal program. Optometry. 2007 Dec; 78(12):657-63.
    View in: PubMed
  74. Pasquale LR, Rosner BA, Hankinson SE, Kang JH. Attributes of female reproductive aging and their relation to primary open-angle glaucoma: a prospective study. J Glaucoma. 2007 Oct-Nov; 16(7):598-605.
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  75. Pasquale LR, Dolgitser M, Wentzloff JN, Stern LS, Doyle JJ, Chiang TH, Walt JG. Health care charges for patients with ocular hypertension or primary open-angle glaucoma. Ophthalmology. 2008 Apr; 115(4):633-638.e4.
    View in: PubMed
  76. Feke GT, Pasquale LR. Retinal blood flow response to posture change in glaucoma patients compared with healthy subjects. Ophthalmology. 2008 Feb; 115(2):246-52.
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  77. Papadaki TG, Zacharopoulos IP, Pasquale LR, Christen WB, Netland PA, Foster CS. Long-term results of Ahmed glaucoma valve implantation for uveitic glaucoma. Am J Ophthalmol. 2007 Jul; 144(1):62-69.
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  78. Pasquale LR, Brandt J, Coleman A, Iwase A. Epidemiology of Intraocular Pressure. AGIS Global Consensus on Intraocular Pressure. 2007; 1-4.
  79. Kang JH, Willett WC, Rosner BA, Hankinson SE, Pasquale LR. Prospective study of alcohol consumption and the risk of primary open-angle glaucoma. Ophthalmic Epidemiol. 2007 May-Jun; 14(3):141-7.
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  80. Pasquale LR. Ask the doctor. Can eye drops for glaucoma affect the heart? Harv Heart Lett. 2007 May; 17(9):8.
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  81. Pasquale, LR. Optimizing therapy for newly diagnosed open-angle glaucoma: Lessons learned from the Collaborative Initial Glacuoma Treatment Study. Arch of Ophthalmol. 2007; in press.
  82. Pasquale LR, Dolgitser M, Wenztloff JN, Stern LS, Doyle JJ, Chiang TH, Walt JG. Healthcare Charges in Patients with Ocular Hypertension and Primary Open-Angle Glaucoma. American Glaucoma Society. 2007.
  83. Pasquale LR. Genes involved in the pathogenesis of primary open-angle glaucoma: in search of the Holy Grail. JAMA. 2007 Jan 17; 297(3):306-7.
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  84. Wentzloff JN, Grosskreutz CL, Pasquale LR, Walton DS, Chen TC. Endophthalmitis after glaucoma drainage implant surgery. Int Ophthalmol Clin. 2007; 47(2):109-15.
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  85. Jones R, Pasquale LR, Pavan-Langston D. Herpes simplex virus: an important etiology for secondary glaucoma. Int Ophthalmol Clin. 2007; 47(2):99-107.
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  86. Gieser DK, Tracey Williams R, O'connell W, Pasquale LR, Rosenthal BP, Walt JG, Katz LM, Siegartel LR, Wang L, Rosenblatt LS, Stern LS, Doyle JJ. Costs and utilization of end-stage glaucoma patients receiving visual rehabilitation care: A U.S. multi-site retrospective study. J of Glaucoma. 2006; 15:419-25.
  87. Graubard MB, Pasquale LR, Grosskreutz CL, Chen TC, Rhee DJ. Complementary and alternative medicine for glaucoma: a review of the literature. Glaucoma Today. 2006; 4:39-41.
  88. Gieser DK, Tracy Williams R, O'Connell W, Pasquale LR, Rosenthal BP, Walt JG, Katz LM, Siegartel LR, Wang L, Rosenblatt LC, Stern LS, Doyle JJ. Costs and utilization of end-stage glaucoma patients receiving visual rehabilitation care: a US multisite retrospective study. J Glaucoma. 2006 Oct; 15(5):419-25.
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  89. Pasquale LR. Open-Angle Glaucoma and Diabetes. Program #76. 2006.
  90. Brauner SC, Chen TC, Hutchinson BT, Chang MA, Pasquale LR, Grosskreutz CL. The course of glaucoma during pregnancy: a retrospective case series. Arch Ophthalmol. 2006 Aug; 124(8):1089-94.
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  91. Wanner JB, Pasquale LR. Glaucomas secondary to intraocular melanomas. Semin Ophthalmol. 2006 Jul-Sep; 21(3):181-9.
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  92. Pasquale LR, Kang JH, Manson JE, Willett WC, Rosner BA, Hankinson SE. Prospective study of type 2 diabetes mellitus and risk of primary open-angle glaucoma in women. Ophthalmology. 2006 Jul; 113(7):1081-6.
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  93. Figuieredo DR, Pasquale LR, Wagner S, DelBono E, Haines JL, Wiggs JL. Genotype phenotype correlations in patients with OPA1 DNA sequence variants. Invest Ophth Vis Sci. 2006.
  94. Pasquale LR, Hankinson SE, Willett WC, Rosner BA, Colditz G, Kang JH. Prospective study of alcohol consumption and risk of primary open-angle glaucoma. Invest Ophthal Vis Sci. 2006.
  95. Monzetuma SR, Pasquale LR. Modelling the number needed to screen for primary open-angle glaucoma. Invest Ophtha Vis Sci. 2006.
  96. Grosskreutz CL, Pasquale LR, Singer MS, Kalayoglu MV. Cyclopentane heptanoic acid, 2-arylalkyl or cycloalkyl derivatives useful for reducing body fat. 2006.
  97. Grosskreutz CL, Paula JS, Pasquale LR. Periorbital fat loss and eyelid sulcus deepening after bimatoprost therapy. American Glaucoma Society. 2006.
  98. Feldman RM, Prager TC, Baker LA, Chuang AZ and Additivity Study Group*. Additivity of brinzolamide vs. brimonidine 0.15% to travoprost 0.004%. American Glaucoma Society. 2006; (*PI for MEEI study site).
  99. Pasquale L, Walt JG, Chiang TH, Katz LM, Stern LS, Doyle JJ, Dolgitser M. Healthcare charges of patients with ocular hypertension. American Glaucoma Society. 2006.
  100. Figueiredo D, Pasquale LR, O'Brien C, Realini A, Alingham R, Hauser MA, Pericak-Vance MA, DelBono E, Haines JL, Wiggs JL. Distribution of NOS3 and p53 genotypes in glaucoma patients after stratification by initial visual field defect. Invest Ophth Vis Sc. 2005.
  101. Zhao JC, Grosskreutz CL, Pasquale LR. Argon versus selective laser trabeculoplasty in the treatment of open angle glaucoma. Int Ophthalmol Clin. 2005; 45(4):97-106.
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  102. Vendal Z, Delbon E, Wiggs J, Pasquale LR. Endophenotypic analysis of glaucoma patients who present with paracentral visual field loss. Invest Ophth Vis Sci. 2005.
  103. Dunphy RW, Fisch BM, Asefzadeh B, Pasquale LR, Selvin G, Cavallerano A. Monochromatic viewing format of fundus images to improve performance characteristics of digital fundus photography. International Society of Imaging of the Eye (ISIE) Ft. Lauderdale, FL. 2005.
  104. Fisch BM, Dunphy RW, Pasquale LR, Asefzadeh B, Selvin G, Cavallerano A, DeVita HS. The VABHS ocular telehealth glaucoma suspect cohort study. American Telemedicine Assoc Annual Meeting, Denver, CO. 2005.
  105. Pasquale LR, Brusie S. Assessment of retinal function (The blue arc test for glaucoma). 2004.
  106. Zhao JC, Zacks DN, Gragoudas ES, Pasquale LR. Pupil sparing excision of an atypical iris melanocytoma induces remission of secondary glaucoma. Br J Ophthalmol. 2004 Jun; 88(6):842-3.
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  107. Kang JH, Pasquale LR, Willett WC, Rosner BA, Egan KM, Faberowski N, Hankinson SE. Dietary fat consumption and primary open-angle glaucoma. Am J Clin Nutr. 2004 May; 79(5):755-64.
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  108. Hoki SL, Zhao J, Pasquale LR. The GON 10.9 project: Long-term visual prognosis of patients with advanced glaucomatous optic neuropathy. Invest Ophthal Vis Sci. 2004.
  109. Fine LC, Chen TC, Grosskreutz CL, Pasquale LR. Management and prevention of thin, cystic blebs. Int Ophthalmol Clin. 2004; 44(1):29-42.
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  110. Pasquale LR, Feke GT, Menke MN, Kuperwaser M, McMeel JW. Effect of bromonidine versus latanoprost on the maintenance of retinal blood flow homoeostasis during postural change in normal-tension glaucoma. Invest Ophth Vis Sci. 2004.
  111. Ho CL, Walton DS, Pasquale LR. Lens extraction for angle-closure glaucoma. Int Ophthalmol Clin. 2004; 44(1):213-28.
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  112. Wanner S, Pasquale LR. What is the effect of LASIK on intraocular pressure?. Mass Soc Eye Phys Surg Newsletter. 2004.
  113. Vendal Z, Pasquale LR. Are any glaucoma medications likely to increase the risk of developing cataracts?. Mass Soc Eye Phys Surg Newsletter. 2004.
  114. Kang JH, Pasquale LR, Rosner BA, Willett WC, Egan KM, Faberowski N, Hankinson SE. Prospective study of cigarette smoking and the risk of primary open-angle glaucoma. Arch Ophthalmol. 2003 Dec; 121(12):1762-8.
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  115. Kang JH, Pasquale LR, Willett W, Rosner B, Egan KM, Faberowski N, Hankinson SE. Antioxidant intake and primary open-angle glaucoma: a prospective study. Am J Epidemiol. 2003 Aug 15; 158(4):337-46.
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  116. Banks MC, Robe-Collignon NJ, Rizzo JF, Pasquale LR. Scanning laser polarimetry of edematous and atrophic optic nerve heads. Arch Ophthalmol. 2003 Apr; 121(4):484-90.
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  117. Fay A, Lee LC, Pasquale LR. Dermatochalasis causing apparent bitemporal hemianopsia. Ophthal Plast Reconstr Surg. 2003 Mar; 19(2):151-3.
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  118. Pasquale LR. What are the side-effects/contraindication for topamax?. Mass Soc Eye Phys Surg Newsletter. 2003.
  119. Kang JH, Pasquale LR, Rosner B, Willet W, Faberowski N, Hankinson SE. Prospective study of antioxidant intake and the risk of primary open-angle glaucoma in two cohorts. Am Journal of Epidemiology. 2003; 158:337-346.
  120. Pasquale LR, Kang J, Rosner B, Willett W, Hankinson S. Age at menopause and primary open-angle glaucoma: A prospective study. Invest Ophthal Vis Sci. 2003.
  121. Halpern DL, Pasquale LR. Cystoid macular edema in aphakia and pseudophakia after use of prostaglandin analogs. Semin Ophthalmol. 2002 Sep-Dec; 17(3-4):181-6.
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  122. Lee LC, Pasquale LR. Surgical management of glaucoma in pseudophakic patients. Semin Ophthalmol. 2002 Sep-Dec; 17(3-4):131-7.
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  123. Maw R, Pineda R, Pasquale LR, Dana MR. Traumatic ruptured globe injuries in children. Int Ophthalmol Clin. 2002; 42(3):157-65.
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  124. Pininnti U, Chen T, Pasquale LR. Glaucoma case studies: Shallow anterior chamber after laser iridotomy. Ophthalmology Management. 2002.
  125. Pasquale LR. Glaucoma specialty clinical update: neovascular glaucoma. American Academy of Ophthalmology. 2002.
  126. Pasquale LR. Glaucoma specialty clinical update: primary open-angle glaucoma. American Academy of Ophthalmology. 2002.
  127. Sankar PS, Chen TC, Grosskreutz CL, Pasquale LR. Traumatic hyphema. Int Ophthalmol Clin. 2002; 42(3):57-68.
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  128. Pasquale LR. Glaucoma Surgery: Past, Present, and Future. Vision and Aging. 2002; 2:16-19.
  129. Sankar PS, Pasquale LR, Grosskreutz CL. Uveal effusion and secondary angle-closure glaucoma associated with topiramate use. Arch Ophthalmol. 2001 Aug; 119(8):1210-1.
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  130. Chen TC, Ang RT, Grosskreutz CL, Pasquale LR, Fan JT. Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery. Ophthalmology. 2001 Jun; 108(6):1033-8.
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  131. Pasquale, LR. Glaucoma the requisites in ophthalmology by Alward AWL. Am J Ophthalmol. 2001; 131:682-3.
  132. Pasquale L, Donato F, Chiesa R, Bonomelli D, Gelatti U, Albertini A, Andreaggi R, Martelli C, Nardi G. [Mortality in the local health unite of Vallecamonia-Sebino (Brescia) in 1980-1997: the impact of smoking, alcohol drinking, and traffic accidents]. Ann Ig. 2001 Jan-Feb; 13(1):49-60.
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  133. Bahabur G, Choplin NT, Lytle RA, Pasquale LR, Sliverstone DE, Higginbotham EJ. Advances in glaucoma diagnosis: Objective detection technology. Ocula Surgery News. 2000.
  134. Iaquinto G, Todisco A, Giardullo N, D'Onofrio V, Pasquale L, De Luca A, Andriulli A, Perri F, Rega C, De Chiara G, Landi M, Taccone W, Leandro G, Figura N. Antibody response to Helicobacter pylori CagA and heat-shock proteins in determining the risk of gastric cancer development. Dig Liver Dis. 2000 Jun-Jul; 32(5):378-83.
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  135. Bohn RL, Gurwitz JH, Yeomans SM, Glynn RJ, Pasquale LR, Walker AM, Avorn J. Which patients are treated for glaucoma? An observational analysis. J Glaucoma. 2000 Feb; 9(1):38-44.
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  136. Gasch AT, Wang P, Pasquale LR. Determinants of glaucoma awareness in a general eye clinic. Ophthalmology. 2000 Feb; 107(2):303-8.
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  137. Pasquale LR. Neuroprotection in glaucoma 2000: Do vitamins reduce the risk of developing primary open-angle glaucoma?. Boston: Ophthalmology Interactive. 2000; CD-ROM.
  138. Gasch AT, Foster CS, Grosskreutz CL, Pasquale LR. Postoperative sympathetic ophthalmia. Int Ophthalmol Clin. 2000; 40(1):69-84.
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  139. Arkel YS, Ku DH, Lake C, Pasquale L, Lam X, Gibson D, Burstin S. A case of type 2B von Willebrand disease reverse to normal when treated with high doses of protease inhibitor. Thromb Haemost. 1999 Nov; 82(5):1558-9.
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  140. Migdal C, Perkins TW, Pasquale L. Management of chronic choroidal effusions. J Glaucoma. 1999 Oct; 8(5):325-7.
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  141. Cavallini MC, Pasquale L, Bellodi L, Smeraldi E. Complex segregation analysis for obsessive compulsive disorder and related disorders. Am J Med Genet. 1999 Feb 5; 88(1):38-43.
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  142. Leuenberger EU, Grosskreutz CL, Walton DS, Pasquale LR. Advances in aqueous shunting procedures. Int Ophthalmol Clin. 1999; 39(1):139-53.
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  143. Chen TC, Pasquale LR, Walton DS, Grosskreutz CL. Diode laser transscleral cyclophotocoagulation. Int Ophthalmol Clin. 1999; 39(1):169-76.
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  144. VanderVeen DK, Pasquale LR, Fulton AB. Central retinal vein occlusion in a young child with cyanotic heart disease. Arch Ophthalmol. 1997 Aug; 115(8):1077.
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  145. Ayaki M, Pasquale LR. Glaucoma laser surgery. Ophthalmology (Tokyo). 1995; 37:995-997.
  146. Pasquale LR. Update on Alpha-2 adrenergic agonists. Review of Ophthalmology. 1995; 2:99-100.
  147. Nordlund JR, Pasquale LR, Robin AL, Rudikoff MT, Ordman J, Chen KS, Walt J. The cardiovascular, pulmonary, and ocular hypotensive effects of 0.2% brimonidine. Arch Ophthalmol. 1995 Jan; 113(1):77-83.
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  148. Pasquale LR. Graft-versus-host-desease and dry eyes. Bone Marrow Transplant Support Group Newsletter. 1995; 4(3).
  149. Aiello LP, Avery RL, Arrigg PG, Keyt BA, Jampel HD, Shah ST, Pasquale LR, Thieme H, Iwamoto MA, Park JE, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med. 1994 Dec 1; 331(22):1480-7.
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  150. Derick RJ, Pasquale LR, Pease ME, Quigley HA. A clinical study of peripapillary crescents of the optic disc in chronic experimental glaucoma in monkey eyes. Arch Ophthalmol. 1994 Jun; 112(6):846-50.
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  151. Pasquale LR, Green WR. Exfoliation syndrome: slit lamp biomicroscopy and pathological findings of the anterior segment. New Trends in Ophthalmology. 1993; 8:117-129.
  152. Pasquale LR, Dorman-Pease ME, Lutty GA, Quigley HA, Jampel HD. Immunolocalization of TGF-beta 1, TGF-beta 2, and TGF-beta 3 in the anterior segment of the human eye. Invest Ophthalmol Vis Sci. 1993 Jan; 34(1):23-30.
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  153. Donato F, Soldo M, Spiazzi R, Chiesa R, Monarca S, Nardi G, Pasquale L, Pezzotti A, Tonini G. [Factors associated with alcohol consumption in the youth of the province of Brescia]. Epidemiol Prev. 1992 Dec; 14(53):40-8.
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  154. Jampel HD, Pasquale LR, Dibernardo C. Hypotony maculopathy following trabeculectomy with mitomycin C. Arch Ophthalmol. 1992 Aug; 110(8):1049-50.
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  155. Pasquale LR, Smith SG. Surgical outcome of phacoemulsification combined with the Pearce trabeculectomy in patients with glaucoma. J Cataract Refract Surg. 1992 May; 18(3):301-5.
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  156. Pasquale LR, Thibault D, Dorman-Pease ME, Quigley HA, Jampel HD. Effect of topical mitomycin C on glaucoma filtration surgery in monkeys. Ophthalmology. 1992 Jan; 99(1):14-8.
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  157. Derick RJ, Pasquale L, Quigley HA, Jampel H. Potential toxicity of mitomycin C. Arch Ophthalmol. 1991 Dec; 109(12):1635.
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  158. Monarca S, Donato F, Modolo MA, Brunelli L, Spiazzi R, Pasquale L, Nardi G. Drinking habits among high school students in Perugia, Italy, in 1981 and 1988: time trends and correlates. Int J Addict. 1991 Oct; 26(10):1107-22.
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  159. Pasquale LR, Smith SG, Traboulsi E, Jampel H. Spontaneous filtration blebs in a patient with microspherophakia. Am J Ophthalmol. 1991 Sep 15; 112(3):350-2.
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  160. Pasquale LR, Romayananda N, Kubacki J, Johnson MH, Chan GH. Congenital cystic eye with multiple ocular and intracranial anomalies. Arch Ophthalmol. 1991 Jul; 109(7):985-7.
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  161. Pasquale LR, Mathias RT, Austin LR, Brink PR, Ciunga M. Electrostatic properties of fiber cell membranes from the frog lens. Biophys J. 1990 Oct; 58(4):939-45.
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  162. Pasquale LR, Moster ML, Schmaier A. Dural sinus thrombosis with abnormalities of protein S and fibrinogen. Arch Ophthalmol. 1990 May; 108(5):644.
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  163. Iaquinto G, Guarino A, Taccone W, Imparato L, Ambrosone L, Giardullo N, Di Scala A, De Renzi E, Pasquale L, Maione A, et al. [Bile acids before and after administration of branched-chain amino acids in acute hepatitis]. Minerva Dietol Gastroenterol. 1987 Jul-Sep; 33(3):217-21.
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  164. Pasquale L, Winiski A, Oliva C, Vaio G, McLaughlin S. An experimental test of new theoretical models for the electrokinetic properties of biological membranes. The effect of UO2++ and tetracaine on the electrophoretic mobility of bilayer membranes and human erythrocytes. J Gen Physiol. 1986 Dec; 88(6):697-718.
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  165. DiToro DM, Mahony J, Kirchgraber P, O'Byrne AL, Pasquale LR, Piccirilli D. Effects of nonreversibility, particle concentration and ionic strength on heavy metal sorption. Env Sci & Tech. 1986; 20:55-61.
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