Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Robert A. Levine, M.D.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Cardiac Ultrasound Lab VB-5
55 Fruit St
Boston MA 02114
Phone617/724-1981
Fax617/726-8383

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Yukawa S, Takeuchi M, Nakazono A, Sakamoto K, Araya K, Eto M, Nishimura Y, Harada M, Levine RA, Otsuji Y. Mitral stenosis reversed by medical treatment for heart failure. Ann Thorac Surg. 2013 Nov; 96(5):e115-7.
    View in: PubMed
  2. Delling FN, Gona P, Larson MG, Lehman B, Manning WJ, Levine RA, Benjamin EJ, Vasan RS. Mild expression of mitral valve prolapse in the framingham offspring: expanding the phenotypic spectrum. J Am Soc Echocardiogr. 2014 Jan; 27(1):17-23.
    View in: PubMed
  3. Nunes MC, Hung J, Barbosa MM, Esteves WA, Carvalho VT, Lodi-Junqueira L, Fonseca Neto CP, Tan TC, Levine RA. Impact of net atrioventricular compliance on clinical outcome in mitral stenosis. Circ Cardiovasc Imaging. 2013 Nov 1; 6(6):1001-8.
    View in: PubMed
  4. Beaudoin J, Levine RA, Guerrero JL, Yosefy C, Sullivan S, Abedat S, Handschumacher MD, Szymanski C, Gilon D, Palmeri NO, Vlahakes GJ, Hajjar RJ, Beeri R. Late repair of ischemic mitral regurgitation does not prevent left ventricular remodeling: importance of timing for beneficial repair. Circulation. 2013 Sep 10; 128(26 Suppl 1):S248-52.
    View in: PubMed
  5. Beaudoin J, Thai WE, Wai B, Handschumacher MD, Levine RA, Truong QA. Assessment of mitral valve adaptation with gated cardiac computed tomography: validation with three-dimensional echocardiography and mechanistic insight to functional mitral regurgitation. Circ Cardiovasc Imaging. 2013 Sep 1; 6(5):784-9.
    View in: PubMed
  6. Dal-Bianco JP, Levine RA. Anatomy of the Mitral Valve Apparatus: Role of 2D and 3D Echocardiography. Cardiol Clin. 2013 May; 31(2):151-64.
    View in: PubMed
  7. Beaudoin J, Handschumacher MD, Zeng X, Hung J, Morris EL, Levine RA, Schwammenthal E. Mitral valve enlargement in chronic aortic regurgitation as a compensatory mechanism to prevent functional mitral regurgitation in the dilated left ventricle. J Am Coll Cardiol. 2013 Apr 30; 61(17):1809-16.
    View in: PubMed
  8. Jensen MO, Hagège AA, Otsuji Y, Levine RA. The unsaddled annulus: biomechanical culprit in mitral valve prolapse? Circulation. 2013 Feb 19; 127(7):766-8.
    View in: PubMed
  9. Rahmani A, Rasmussen AQ, Honge JL, Ostli B, Levine RA, Hagège A, Nygaard H, Nielsen SL, Jensen MO. Mitral valve mechanics following posterior leaflet patch augmentation. J Heart Valve Dis. 2013 Jan; 22(1):28-35.
    View in: PubMed
  10. Szymanski C, Bel A, Cohen I, Touchot B, Handschumacher MD, Desnos M, Carpentier A, Menasché P, Hagège AA, Levine RA, Messas E. Comprehensive annular and subvalvular repair of chronic ischemic mitral regurgitation improves long-term results with the least ventricular remodeling. Circulation. 2012 Dec 4; 126(23):2720-7.
    View in: PubMed
  11. Otani K, Takeuchi M, Kaku K, Haruki N, Yoshitani H, Eto M, Tamura M, Okazaki M, Abe H, Fujino Y, Nishimura Y, Levine RA, Otsuji Y. Evidence of a vicious cycle in mitral regurgitation with prolapse: secondary tethering attributed to primary prolapse demonstrated by three-dimensional echocardiography exacerbates regurgitation. Circulation. 2012 Sep 11; 126(11 Suppl 1):S214-21.
    View in: PubMed
  12. Gu JW, Herrmann BS, Levine RA, Melcher JR. Brainstem auditory evoked potentials suggest a role for the ventral cochlear nucleus in tinnitus. J Assoc Res Otolaryngol. 2012 Dec; 13(6):819-33.
    View in: PubMed
  13. Sauls K, de Vlaming A, Harris BS, Williams K, Wessels A, Levine RA, Slaugenhaupt SA, Goodwin RL, Pavone LM, Merot J, Schott JJ, Le Tourneau T, Dix T, Jesinkey S, Feng Y, Walsh C, Zhou B, Baldwin S, Markwald RR, Norris RA. Developmental basis for filamin-A-associated myxomatous mitral valve disease. Cardiovasc Res. 2012 Oct 1; 96(1):109-19.
    View in: PubMed
  14. Ofman P, Cook JR, Navaravong L, Levine RA, Peralta A, Gaziano JM, Djousse L, Curillova Z, Hoffmeister P, Smoot K, Jiang L, Tighe DA, Stoenescu ML. T-wave inversion and diastolic dysfunction in patients with electrocardiographic left ventricular hypertrophy. J Electrocardiol. 2012 Nov; 45(6):764-9.
    View in: PubMed
  15. Beaudoin J, Levine RA, Yosefy C, Beeri R, Neary JH, Morgan NV, Passeri JJ. Severe ischemic mitral regurgitation despite normally contracting subpapillary myocardium. Circulation. 2012 Jul 3; 126(1):138-41.
    View in: PubMed
  16. Nakai H, Kaku K, Takeuchi M, Otani K, Yoshitani H, Haruki N, Tamura M, Okazaki M, Abe H, Tsutsumi A, Levine RA, Otsuji Y. Different influences of left ventricular remodeling on anterior and posterior mitral leaflet tethering. Circ J. 2012 Sep 25; 76(10):2481-7.
    View in: PubMed
  17. de Vlaming A, Sauls K, Hajdu Z, Visconti RP, Mehesz AN, Levine RA, Slaugenhaupt SA, Hagège A, Chester AH, Markwald RR, Norris RA. Atrioventricular valve development: new perspectives on an old theme. Differentiation. 2012 Jul; 84(1):103-16.
    View in: PubMed
  18. Melcher JR, Knudson IM, Levine RA. Subcallosal brain structure: Correlation with hearing threshold at supra-clinical frequencies (>8 kHz), but not with tinnitus. Hear Res. 2013 Jan; 295(1-2):79-86.
    View in: PubMed
  19. Hung J, Solis J, Handschumacher MD, Guerrero JL, Levine RA. Persistence of mitral regurgitation following ring annuloplasty: is the papillary muscle outside or inside the ring? J Heart Valve Dis. 2012 Mar; 21(2):218-24.
    View in: PubMed
  20. Meris A, Amigoni M, Verma A, Thune JJ, Køber L, Velazquez E, McMurray JJ, Pfeffer MA, Califf R, Levine RA, Solomon SD. Mechanisms and predictors of mitral regurgitation after high-risk myocardial infarction. J Am Soc Echocardiogr. 2012 May; 25(5):535-42.
    View in: PubMed
  21. Kim K, Kaji S, An Y, Yoshitani H, Takeuchi M, Levine RA, Otsuji Y, Furukawa Y. Mechanism of asymmetric leaflet tethering in ischemic mitral regurgitation: 3D analysis with multislice CT. JACC Cardiovasc Imaging. 2012 Feb; 5(2):230-2.
    View in: PubMed
  22. Granier M, Jensen MO, Honge JL, Bel A, Menasché P, Nielsen SL, Carpentier A, Levine RA, Hagège AA. Consequences of mitral valve prolapse on chordal tension: ex vivo and in vivo studies in large animal models. J Thorac Cardiovasc Surg. 2011 Dec; 142(6):1585-7.
    View in: PubMed
  23. Szymanski C, Levine RA, Tribouilloy C, Zheng H, Handschumacher MD, Tawakol A, Hung J. Impact of mitral regurgitation on exercise capacity and clinical outcomes in patients with ischemic left ventricular dysfunction. Am J Cardiol. 2011 Dec 15; 108(12):1714-20.
    View in: PubMed
  24. Hagège AA, Bruneval P, Levine RA, Desnos M, Neamatalla H, Judge DP. The mitral valve in hypertrophic cardiomyopathy: old versus new concepts. J Cardiovasc Transl Res. 2011 Dec; 4(6):757-66.
    View in: PubMed
  25. Judge DP, Markwald RR, Hagège AA, Levine RA. Translational research on the mitral valve: from developmental mechanisms to new therapies. J Cardiovasc Transl Res. 2011 Dec; 4(6):699-701.
    View in: PubMed
  26. Zeng X, Levine RA, Hua L, Morris EL, Kang Y, Flaherty M, Morgan NV, Hung J. Diagnostic value of vena contracta area in the quantification of mitral regurgitation severity by color Doppler 3D echocardiography. Circ Cardiovasc Imaging. 2011 Sep; 4(5):506-13.
    View in: PubMed
  27. Yosefy C, Beeri R, Guerrero JL, Vaturi M, Scherrer-Crosbie M, Handschumacher MD, Levine RA. Mitral regurgitation after anteroapical myocardial infarction: new mechanistic insights. Circulation. 2011 Apr 12; 123(14):1529-36.
    View in: PubMed
  28. Jensen MO, Jensen H, Levine RA, Yoganathan AP, Andersen NT, Nygaard H, Hasenkam JM, Nielsen SL. Saddle-shaped mitral valve annuloplasty rings improve leaflet coaptation geometry. J Thorac Cardiovasc Surg. 2011 Sep; 142(3):697-703.
    View in: PubMed
  29. Wylie-Sears J, Aikawa E, Levine RA, Yang JH, Bischoff J. Mitral valve endothelial cells with osteogenic differentiation potential. Arterioscler Thromb Vasc Biol. 2011 Mar; 31(3):598-607.
    View in: PubMed
  30. Gu JW, Halpin CF, Nam EC, Levine RA, Melcher JR. Tinnitus, diminished sound-level tolerance, and elevated auditory activity in humans with clinically normal hearing sensitivity. J Neurophysiol. 2010 Dec; 104(6):3361-70.
    View in: PubMed
  31. Kim DH, Handschumacher MD, Levine RA, Choi YS, Kim YJ, Yun SC, Song JM, Kang DH, Song JK. In vivo measurement of mitral leaflet surface area and subvalvular geometry in patients with asymmetrical septal hypertrophy: insights into the mechanism of outflow tract obstruction. Circulation. 2010 Sep 28; 122(13):1298-307.
    View in: PubMed
  32. Messas E, Bel A, Szymanski C, Cohen I, Touchot B, Handschumacher MD, Desnos M, Carpentier A, Menasché P, Hagège AA, Levine RA. Relief of mitral leaflet tethering following chronic myocardial infarction by chordal cutting diminishes left ventricular remodeling. Circ Cardiovasc Imaging. 2010 Nov; 3(6):679-86.
    View in: PubMed
  33. Solis J, Levine RA, Johnson B, Guerrero JL, Handschumacher MD, Sullivan S, Lam K, Berlin J, Braithwaite GJ, Muratoglu OK, Vlahakes GJ, Hung J. Polymer injection therapy to reverse remodel the papillary muscles: efficacy in reducing mitral regurgitation in a chronic ischemic model. Circ Cardiovasc Interv. 2010 Oct; 3(5):499-505.
    View in: PubMed
  34. Levine RA, Nattel S. Looking into the left atrial crystal ball: a ray of hope for patients with organic mitral regurgitation. J Am Coll Cardiol. 2010 Aug 10; 56(7):579-81.
    View in: PubMed
  35. Beeri R, Chaput M, Guerrero JL, Kawase Y, Yosefy C, Abedat S, Karakikes I, Morel C, Tisosky A, Sullivan S, Handschumacher MD, Gilon D, Vlahakes GJ, Hajjar RJ, Levine RA. Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation. Circ Heart Fail. 2010 Sep; 3(5):627-34.
    View in: PubMed
  36. Kubota K, Otsuji Y, Ueno T, Koriyama C, Levine RA, Sakata R, Tei C. Functional mitral stenosis after surgical annuloplasty for ischemic mitral regurgitation: importance of subvalvular tethering in the mechanism and dynamic deterioration during exertion. J Thorac Cardiovasc Surg. 2010 Sep; 140(3):617-23.
    View in: PubMed
  37. Yosefy C, Hung J, Chua S, Vaturi M, Ton-Nu TT, Handschumacher MD, Levine RA. Direct measurement of vena contracta area by real-time 3-dimensional echocardiography for assessing severity of mitral regurgitation. Am J Cardiol. 2009 Oct 1; 104(7):978-83.
    View in: PubMed
  38. Solis J, McCarty D, Levine RA, Handschumacher MD, Fernandez-Friera L, Chen-Tournoux A, Mont L, Vidal B, Singh JP, Brugada J, Picard MH, Sitges M, Hung J. Mechanism of decrease in mitral regurgitation after cardiac resynchronization therapy: optimization of the force-balance relationship. Circ Cardiovasc Imaging. 2009 Nov; 2(6):444-50.
    View in: PubMed
  39. Chaput M, Handschumacher MD, Guerrero JL, Holmvang G, Dal-Bianco JP, Sullivan S, Vlahakes GJ, Hung J, Levine RA. Mitral leaflet adaptation to ventricular remodeling: prospective changes in a model of ischemic mitral regurgitation. Circulation. 2009 Sep 15; 120(11 Suppl):S99-103.
    View in: PubMed
  40. Melcher JR, Levine RA, Bergevin C, Norris B. The auditory midbrain of people with tinnitus: abnormal sound-evoked activity revisited. Hear Res. 2009 Nov; 257(1-2):63-74.
    View in: PubMed
  41. Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Handschumacher MD, Sullivan S, Johnson B, Titus JS, Iwamoto Y, Wylie-Sears J, Levine RA, Carpentier A. Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation. Circulation. 2009 Jul 28; 120(4):334-42.
    View in: PubMed
  42. Chua S, Levine RA, Yosefy C, Handschumacher MD, Chu J, Qureshi A, Neary J, Ton-Nu TT, Fu M, Wu CJ, Hung J. Assessment of right ventricular function by real-time three-dimensional echocardiography improves accuracy and decreases interobserver variability compared with conventional two-dimensional views. Eur J Echocardiogr. 2009 Jul; 10(5):619-24.
    View in: PubMed
  43. Yared K, Solis J, Passeri J, King ME, Levine RA. Three-dimensional echocardiographic assessment of acquired left ventricular to right atrial shunt (Gerbode defect). J Am Soc Echocardiogr. 2009 Apr; 22(4):435.e1-3.
    View in: PubMed
  44. Solis J, Sitges M, Levine RA, Hung J. Three-dimensional echocardiography. New possibilities in mitral valve assessment. Rev Esp Cardiol. 2009 Feb; 62(2):188-98.
    View in: PubMed
  45. Jensen MO, Jensen H, Smerup M, Levine RA, Yoganathan AP, Nygaard H, Hasenkam JM, Nielsen SL. Saddle-shaped mitral valve annuloplasty rings experience lower forces compared with flat rings. Circulation. 2008 Sep 30; 118(14 Suppl):S250-5.
    View in: PubMed
  46. Hung J, Solis J, Guerrero JL, Braithwaite GJ, Muratoglu OK, Chaput M, Fernandez-Friera L, Handschumacher MD, Wedeen VJ, Houser S, Vlahakes GJ, Levine RA. A novel approach for reducing ischemic mitral regurgitation by injection of a polymer to reverse remodel and reposition displaced papillary muscles. Circulation. 2008 Sep 30; 118(14 Suppl):S263-9.
    View in: PubMed
  47. Chaput M, Handschumacher MD, Tournoux F, Hua L, Guerrero JL, Vlahakes GJ, Levine RA. Mitral leaflet adaptation to ventricular remodeling: occurrence and adequacy in patients with functional mitral regurgitation. Circulation. 2008 Aug 19; 118(8):845-52.
    View in: PubMed
  48. Chu JW, Levine RA, Chua S, Poh KK, Morris E, Hua L, Ton-Nu TT, Hung J. Assessing mitral valve area and orifice geometry in calcific mitral stenosis: a new solution by real-time three-dimensional echocardiography. J Am Soc Echocardiogr. 2008 Sep; 21(9):1006-9.
    View in: PubMed
  49. Levine RA, Durst R. Mitral valve prolapse: a deeper look. JACC Cardiovasc Imaging. 2008 May; 1(3):304-6.
    View in: PubMed
  50. Otsuji Y, Levine RA, Takeuchi M, Sakata R, Tei C. Mechanism of ischemic mitral regurgitation. J Cardiol. 2008 Jun; 51(3):145-56.
    View in: PubMed
  51. Neilan TG, Ton-Nu TT, Kawase Y, Yoneyama R, Hoshino K, Del Monte F, Hajjar RJ, Picard MH, Levine RA, Hung J. Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes. Am J Physiol Heart Circ Physiol. 2008 May; 294(5):H2106-11.
    View in: PubMed
  52. Buck T, Hwang SM, Plicht B, Mucci RA, Hunold P, Erbel R, Levine RA. Automated flow quantification in valvular heart disease based on backscattered Doppler power analysis: implementation on matrix-array ultrasound imaging systems. Int J Cardiovasc Imaging. 2008 Jun; 24(5):463-77.
    View in: PubMed
  53. Poh KK, Levine RA, Solis J, Shen L, Flaherty M, Kang YJ, Guerrero JL, Hung J. Assessing aortic valve area in aortic stenosis by continuity equation: a novel approach using real-time three-dimensional echocardiography. Eur Heart J. 2008 Oct; 29(20):2526-35.
    View in: PubMed
  54. Beeri R, Yosefy C, Guerrero JL, Nesta F, Abedat S, Chaput M, del Monte F, Handschumacher MD, Stroud R, Sullivan S, Pugatsch T, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA. Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation. J Am Coll Cardiol. 2008 Jan 29; 51(4):476-86.
    View in: PubMed
  55. Delling FN, Sanborn DY, Levine RA, Picard MH, Fifer MA, Palacios IF, Lowry PA, Vlahakes GJ, Vaturi M, Hung J. Frequency and mechanism of persistent systolic anterior motion and mitral regurgitation after septal ablation in obstructive hypertrophic cardiomyopathy. Am J Cardiol. 2007 Dec 1; 100(11):1691-5.
    View in: PubMed
  56. Beeri R, Yosefy C, Guerrero JL, Abedat S, Handschumacher MD, Stroud RE, Sullivan S, Chaput M, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA. Early repair of moderate ischemic mitral regurgitation reverses left ventricular remodeling: a functional and molecular study. Circulation. 2007 Sep 11; 116(11 Suppl):I288-93.
    View in: PubMed
  57. Hung J, Chaput M, Guerrero JL, Handschumacher MD, Papakostas L, Sullivan S, Solis J, Levine RA. Persistent reduction of ischemic mitral regurgitation by papillary muscle repositioning: structural stabilization of the papillary muscle-ventricular wall complex. Circulation. 2007 Sep 11; 116(11 Suppl):I259-63.
    View in: PubMed
  58. Yosefy C, Levine RA, Picard MH, Vaturi M, Handschumacher MD, Isselbacher EM. Pseudodyskinesis of the inferior left ventricular wall: recognizing an echocardiographic mimic of myocardial infarction. J Am Soc Echocardiogr. 2007 Dec; 20(12):1374-9.
    View in: PubMed
  59. Beeri R, Streckenbach SC, Isselbacher EM, Akins CW, Vlahakes GJ, Adams MS, Levine RA. The crossed swords sign: insights into the dilemma of repair in bileaflet mitral valve prolapse. J Am Soc Echocardiogr. 2007 Jun; 20(6):698-702.
    View in: PubMed
  60. Levine RA, Slaugenhaupt SA. Molecular genetics of mitral valve prolapse. Curr Opin Cardiol. 2007 May; 22(3):171-5.
    View in: PubMed
  61. Yosefy C, Levine RA, Solis J, Vaturi M, Handschumacher MD, Hung J. Proximal flow convergence region as assessed by real-time 3-dimensional echocardiography: challenging the hemispheric assumption. J Am Soc Echocardiogr. 2007 Apr; 20(4):389-96.
    View in: PubMed
  62. Mele D, Soukhomovskaia O, Pacchioni E, Merli E, Avigni N, Federici L, Levine RA, Ferrari R. Improved detection of left ventricular thrombi and spontaneous echocontrast by tissue harmonic imaging in patients with myocardial infarction. J Am Soc Echocardiogr. 2006 Nov; 19(11):1373-81.
    View in: PubMed
  63. Kuwahara E, Otsuji Y, Iguro Y, Ueno T, Zhu F, Mizukami N, Kubota K, Nakashiki K, Yuasa T, Yu B, Uemura T, Takasaki K, Miyata M, Hamasaki S, Kisanuki A, Levine RA, Sakata R, Tei C. Mechanism of recurrent/persistent ischemic/functional mitral regurgitation in the chronic phase after surgical annuloplasty: importance of augmented posterior leaflet tethering. Circulation. 2006 Jul 4; 114(1 Suppl):I529-34.
    View in: PubMed
  64. Messas E, Yosefy C, Chaput M, Guerrero JL, Sullivan S, Menasché P, Carpentier A, Desnos M, Hagege AA, Vlahakes GJ, Levine RA. Chordal cutting does not adversely affect left ventricle contractile function. Circulation. 2006 Jul 4; 114(1 Suppl):I524-8.
    View in: PubMed
  65. Ton-Nu TT, Levine RA, Handschumacher MD, Dorer DJ, Yosefy C, Fan D, Hua L, Jiang L, Hung J. Geometric determinants of functional tricuspid regurgitation: insights from 3-dimensional echocardiography. Circulation. 2006 Jul 11; 114(2):143-9.
    View in: PubMed
  66. Messas E, Bel A, Morichetti MC, Carrion C, Handschumacher MD, Peyrard S, Vilquin JT, Desnos M, Bruneval P, Carpentier A, Menasché P, Levine RA, Hagège AA. Autologous myoblast transplantation for chronic ischemic mitral regurgitation. J Am Coll Cardiol. 2006 May 16; 47(10):2086-93.
    View in: PubMed
  67. Levine RA. Typewriter tinnitus: a carbamazepine-responsive syndrome related to auditory nerve vascular compression. ORL J Otorhinolaryngol Relat Spec. 2006; 68(1):43-6; discussion 46-7.
    View in: PubMed
  68. Nesta F, Leyne M, Yosefy C, Simpson C, Dai D, Marshall JE, Hung J, Slaugenhaupt SA, Levine RA. New locus for autosomal dominant mitral valve prolapse on chromosome 13: clinical insights from genetic studies. Circulation. 2005 Sep 27; 112(13):2022-30.
    View in: PubMed
  69. Zhu F, Otsuji Y, Yotsumoto G, Yuasa T, Ueno T, Yu B, Koriyama C, Hamasaki S, Biro S, Kisanuki A, Minagoe S, Levine RA, Sakata R, Tei C. Mechanism of persistent ischemic mitral regurgitation after annuloplasty: importance of augmented posterior mitral leaflet tethering. Circulation. 2005 Aug 30; 112(9 Suppl):I396-401.
    View in: PubMed
  70. Sebag IA, Morgan JG, Handschumacher MD, Marshall JE, Nesta F, Hung J, Picard MH, Levine RA. Usefulness of three-dimensionally guided assessment of mitral stenosis using matrix-array ultrasound. Am J Cardiol. 2005 Oct 15; 96(8):1151-6.
    View in: PubMed
  71. Levine RA, Schwammenthal E. Ischemic mitral regurgitation on the threshold of a solution: from paradoxes to unifying concepts. Circulation. 2005 Aug 2; 112(5):745-58.
    View in: PubMed
  72. Uemura T, Otsuji Y, Nakashiki K, Yoshifuku S, Maki Y, Yu B, Mizukami N, Kuwahara E, Hamasaki S, Biro S, Kisanuki A, Minagoe S, Levine RA, Tei C. Papillary muscle dysfunction attenuates ischemic mitral regurgitation in patients with localized basal inferior left ventricular remodeling: insights from tissue Doppler strain imaging. J Am Coll Cardiol. 2005 Jul 5; 46(1):113-9.
    View in: PubMed
  73. Schwammenthal E, Levine RA. The non-ischaemic dynamics of ischaemic mitral regurgitation: solving the paradox. Eur Heart J. 2005 Aug; 26(15):1454-5.
    View in: PubMed
  74. Vaturi M, Levine RA, Yosefy C, O'Neil MJ, Picard MH, Hung J. Usefulness of left atrial emptying fraction to predict exercise capacity in patients with normal systolic left ventricular function and without myocardial ischemia. Am J Cardiol. 2005 Apr 15; 95(8):1014-7.
    View in: PubMed
  75. Buck T, Plicht B, Hunold P, Mucci RA, Erbel R, Levine RA. Broad-beam spectral Doppler sonification of the vena contracta using matrix-array technology: A new solution for semi-automated quantification of mitral regurgitant flow volume and orifice area. J Am Coll Cardiol. 2005 Mar 1; 45(5):770-9.
    View in: PubMed
  76. Otsuji Y, Kuwahara E, Yuge K, Yotsumoto G, Ueno T, Nakashiki K, Hamasaki S, Biro S, Minagoe S, Levine RA, Sakata R, Tei C. Relation of aneurysmectomy in patients with advanced left ventricular remodeling to postoperative left ventricular filling pressure, redilatation with ischemic mitral regurgitation. Am J Cardiol. 2005 Feb 15; 95(4):517-21.
    View in: PubMed
  77. Levine RA. Dynamic mitral regurgitation--more than meets the eye. N Engl J Med. 2004 Oct 14; 351(16):1681-4.
    View in: PubMed
  78. Levine RA, Messas E, Nathan NS, Rudski LG. New understanding of ischemic mitral regurgitation: the marionette and its masters. Eur J Echocardiogr. 2004 Oct; 5(5):313-7.
    View in: PubMed
  79. Hung J, Papakostas L, Tahta SA, Hardy BG, Bollen BA, Duran CM, Levine RA. Mechanism of recurrent ischemic mitral regurgitation after annuloplasty: continued LV remodeling as a moving target. Circulation. 2004 Sep 14; 110(11 Suppl 1):II85-90.
    View in: PubMed
  80. Chi H, Messas E, Levine RA, Graves DT, Amar S. Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications. Circulation. 2004 Sep 21; 110(12):1678-85.
    View in: PubMed
  81. Rudski LG, Chow CM, Levine RA. Prosthetic mitral regurgitation can be mimicked by Doppler color flow mapping: avoiding misdiagnosis. J Am Soc Echocardiogr. 2004 Aug; 17(8):829-33.
    View in: PubMed
  82. Yosefy C, Vaturi M, Levine RA. An acute hypertensive episode triggered by an ambulatory blood-pressure-monitoring device. N Engl J Med. 2004 May 27; 350(22):2315-6.
    View in: PubMed
  83. Levine RA, Hung J. Ischemic mitral regurgitation, the dynamic lesion: clues to the cure. J Am Coll Cardiol. 2003 Dec 3; 42(11):1929-32.
    View in: PubMed
  84. Nesta F, Otsuji Y, Handschumacher MD, Messas E, Leavitt M, Carpentier A, Levine RA, Hung J. Leaflet concavity: a rapid visual clue to the presence and mechanism of functional mitral regurgitation. J Am Soc Echocardiogr. 2003 Dec; 16(12):1301-8.
    View in: PubMed
  85. Messas E, Pouzet B, Touchot B, Guerrero JL, Vlahakes GJ, Desnos M, Menasché P, Hagège A, Levine RA. Efficacy of chordal cutting to relieve chronic persistent ischemic mitral regurgitation. Circulation. 2003 Sep 9; 108 Suppl 1:II111-5.
    View in: PubMed
  86. Playford DA, Levine RA, Picard MH, Handschumacher MD. Illusion of contraction from out-of-plane translation: can Doppler tissue velocities resolve it? J Am Soc Echocardiogr. 2003 Aug; 16(8):832-40.
    View in: PubMed
  87. Freed LA, Acierno JS, Dai D, Leyne M, Marshall JE, Nesta F, Levine RA, Slaugenhaupt SA. A locus for autosomal dominant mitral valve prolapse on chromosome 11p15.4. Am J Hum Genet. 2003 Jun; 72(6):1551-9.
    View in: PubMed
  88. Fox ER, Picard MH, Chow CM, Levine RA, Schwamm L, Kerr AJ. Interatrial septal mobility predicts larger shunts across patent foramen ovales: an analysis with transmitral Doppler scanning. Am Heart J. 2003 Apr; 145(4):730-6.
    View in: PubMed
  89. Levine RA, Schwammenthal E. Stenosis is in the eye of the observer: impact of pressure recovery on assessing aortic valve area. J Am Coll Cardiol. 2003 Feb 5; 41(3):443-5.
    View in: PubMed
  90. Kumanohoso T, Otsuji Y, Yoshifuku S, Matsukida K, Koriyama C, Kisanuki A, Minagoe S, Levine RA, Tei C. Mechanism of higher incidence of ischemic mitral regurgitation in patients with inferior myocardial infarction: quantitative analysis of left ventricular and mitral valve geometry in 103 patients with prior myocardial infarction. J Thorac Cardiovasc Surg. 2003 Jan; 125(1):135-43.
    View in: PubMed
  91. Hung J, Guerrero JL, Handschumacher MD, Supple G, Sullivan S, Levine RA. Reverse ventricular remodeling reduces ischemic mitral regurgitation: echo-guided device application in the beating heart. Circulation. 2002 Nov 12; 106(20):2594-600.
    View in: PubMed
  92. Gilon D, Cape EG, Handschumacher MD, Song JK, Solheim J, VanAuker M, King ME, Levine RA. Effect of three-dimensional valve shape on the hemodynamics of aortic stenosis: three-dimensional echocardiographic stereolithography and patient studies. J Am Coll Cardiol. 2002 Oct 16; 40(8):1479-86.
    View in: PubMed
  93. Freed LA, Benjamin EJ, Levy D, Larson MG, Evans JC, Fuller DL, Lehman B, Levine RA. Mitral valve prolapse in the general population: the benign nature of echocardiographic features in the Framingham Heart Study. J Am Coll Cardiol. 2002 Oct 2; 40(7):1298-304.
    View in: PubMed
  94. Beeri R, Guerrero JL, Supple G, Sullivan S, Levine RA, Hajjar RJ. New efficient catheter-based system for myocardial gene delivery. Circulation. 2002 Oct 1; 106(14):1756-9.
    View in: PubMed
  95. Freed LA, Levy D, Levine RA, Evans JC, Larson MG, Fuller DL, Lehman B, Benjamin EJ. Mitral valve prolapse and atrial septal aneurysm: an evaluation in the Framingham Heart Study. Am J Cardiol. 2002 Jun 1; 89(11):1326-9.
    View in: PubMed
  96. Otsuji Y, Kumanohoso T, Yoshifuku S, Matsukida K, Koriyama C, Kisanuki A, Minagoe S, Levine RA, Tei C. Isolated annular dilation does not usually cause important functional mitral regurgitation: comparison between patients with lone atrial fibrillation and those with idiopathic or ischemic cardiomyopathy. J Am Coll Cardiol. 2002 May 15; 39(10):1651-6.
    View in: PubMed
  97. Levine RA, Hung J, Otsuji Y, Messas E, Liel-Cohen N, Nathan N, Handschumacher MD, Guerrero JL, He S, Yoganathan AP, Vlahakes GJ. Mechanistic insights into functional mitral regurgitation. Curr Cardiol Rep. 2002 Mar; 4(2):125-9.
    View in: PubMed
  98. Li L, Messas E, Batista EL, Levine RA, Amar S. Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model. Circulation. 2002 Feb 19; 105(7):861-7.
    View in: PubMed
  99. Klima UP, Lee MY, Guerrero JL, Laraia PJ, Levine RA, Vlahakes GJ. Determinants of maximal right ventricular function: role of septal shift. J Thorac Cardiovasc Surg. 2002 Jan; 123(1):72-80.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Levine's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_