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William Shih, PH.D.

TitleAssociate Professor of Biological Chemistry and Molecular Pharmacology
InstitutionDana-Farber Cancer Institute
DepartmentBiological Chemistry & Molecular Pharmacology
AddressDana Farber Cancer Institute
Smith 1058-C, Cancer Biology
44 Binney St
Boston MA 02115
Phone617/632-5143

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Pfitzner E, Wachauf C, Kilchherr F, Pelz B, Shih WM, Rief M, Dietz H. Rigid DNA beams for high-resolution single-molecule mechanics. Angew Chem Int Ed Engl. 2013 Jul 22; 52(30):7766-71.
    View in: PubMed
  2. Ducani C, Kaul C, Moche M, Shih WM, Högberg B. Enzymatic production of 'monoclonal stoichiometric' single-stranded DNA oligonucleotides. Nat Methods. 2013 Jul; 10(7):647-52.
    View in: PubMed
  3. Bellot G, McClintock MA, Chou JJ, Shih WM. DNA nanotubes for NMR structure determination of membrane proteins. Nat Protoc. 2013 Mar 21; 8(4):755-70.
    View in: PubMed
  4. Ke Y, Ong LL, Shih WM, Yin P. Three-dimensional structures self-assembled from DNA bricks. Science. 2012 Nov 30; 338(6111):1177-83.
    View in: PubMed
  5. Lin C, Perrault SD, Kwak M, Graf F, Shih WM. Purification of DNA-origami nanostructures by rate-zonal centrifugation. Nucleic Acids Res. 2013 Jan 1; 41(2):e40.
    View in: PubMed
  6. Derr ND, Goodman BS, Jungmann R, Leschziner AE, Shih WM, Reck-Peterson SL. Tug-of-war in motor protein ensembles revealed with a programmable DNA origami scaffold. Science. 2012 Nov 2; 338(6107):662-5.
    View in: PubMed
  7. Lin C, Jungmann R, Leifer AM, Li C, Levner D, Church GM, Shih WM, Yin P. Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA. Nat Chem. 2012 Oct; 4(10):832-9.
    View in: PubMed
  8. Ke Y, Voigt NV, Gothelf KV, Shih WM. Multilayer DNA origami packed on hexagonal and hybrid lattices. J Am Chem Soc. 2012 Jan 25; 134(3):1770-4.
    View in: PubMed
  9. Qiu W, Derr ND, Goodman BS, Villa E, Wu D, Shih W, Reck-Peterson SL. Dynein achieves processive motion using both stochastic and coordinated stepping. Nat Struct Mol Biol. 2012 Feb; 19(2):193-200.
    View in: PubMed
  10. Pinheiro AV, Han D, Shih WM, Yan H. Challenges and opportunities for structural DNA nanotechnology. Nat Nanotechnol. 2011 Dec; 6(12):763-72.
    View in: PubMed
  11. Berardi MJ, Shih WM, Harrison SC, Chou JJ. Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching. Nature. 2011 Aug 4; 476(7358):109-13.
    View in: PubMed
  12. Bellot G, McClintock MA, Lin C, Shih WM. Recovery of intact DNA nanostructures after agarose gel-based separation. Nat Methods. 2011 Mar; 8(3):192-4.
    View in: PubMed
  13. Liedl T, Högberg B, Tytell J, Ingber DE, Shih WM. Self-assembly of three-dimensional prestressed tensegrity structures from DNA. Nat Nanotechnol. 2010 Jul; 5(7):520-4.
    View in: PubMed
  14. Shih WM, Lin C. Knitting complex weaves with DNA origami. Curr Opin Struct Biol. 2010 Jun; 20(3):276-82.
    View in: PubMed
  15. Ke Y, Douglas SM, Liu M, Sharma J, Cheng A, Leung A, Liu Y, Shih WM, Yan H. Multilayer DNA origami packed on a square lattice. J Am Chem Soc. 2009 Nov 4; 131(43):15903-8.
    View in: PubMed
  16. Dietz H, Douglas SM, Shih WM. Folding DNA into twisted and curved nanoscale shapes. Science. 2009 Aug 7; 325(5941):725-30.
    View in: PubMed
  17. Högberg B, Liedl T, Shih WM. Folding DNA origami from a double-stranded source of scaffold. J Am Chem Soc. 2009 Jul 8; 131(26):9154-5.
    View in: PubMed
  18. Douglas SM, Marblestone AH, Teerapittayanon S, Vazquez A, Church GM, Shih WM. Rapid prototyping of 3D DNA-origami shapes with caDNAno. Nucleic Acids Res. 2009 Aug; 37(15):5001-6.
    View in: PubMed
  19. Douglas SM, Dietz H, Liedl T, Högberg B, Graf F, Shih WM. Self-assembly of DNA into nanoscale three-dimensional shapes. Nature. 2009 May 21; 459(7245):414-8.
    View in: PubMed
  20. Jungmann R, Liedl T, Sobey TL, Shih W, Simmel FC. Isothermal assembly of DNA origami structures using denaturing agents. J Am Chem Soc. 2008 Aug 6; 130(31):10062-3.
    View in: PubMed
  21. Shih W. Biomolecular assembly: dynamic DNA. Nat Mater. 2008 Feb; 7(2):98-100.
    View in: PubMed
  22. Douglas SM, Chou JJ, Shih WM. DNA-nanotube-induced alignment of membrane proteins for NMR structure determination. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6644-8.
    View in: PubMed
  23. Shih WM, Quispe JD, Joyce GF. A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron. Nature. 2004 Feb 12; 427(6975):618-21.
    View in: PubMed
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