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Last Name
Institution

Frances Elizabeth Jensen, M.D.

TitleVisiting Professor of Neurology
InstitutionChildren's Hospital Boston
DepartmentNeurology
AddressChildrens Hospital
C L S 14
300 Longwood Ave
Boston MA 02115
Phone617/919-2445
Fax617/919-2769

 Mentoring 
 completed student projects
Altered FMRP activity in the hippocampus of TSC1 knockout mice corrected by rapamycin treatment
Summer, 06/14/10 - 08/13/10
Role of the NMDA Receptor Subunit NR3A in Epileptogenesis and Tuberous Sclerosis Complex
Summer, 06/06/05 - 08/12/05

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sun H, Kosaras B, Klein PM, Jensen FE. Mammalian target of rapamycin complex 1 activation negatively regulates Polo-like kinase 2-mediated homeostatic compensation following neonatal seizures. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):5199-204.
    View in: PubMed
  2. Cleary RT, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Kahle KT, Jackson M, Rakhade SN, Berry G, Jensen FE. Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures. PLoS One. 2013; 8(3):e57148.
    View in: PubMed
  3. Rakhade SN, Fitzgerald EF, Klein PM, Zhou C, Sun H, Hunganir RL, Jensen FE. Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. J Neurosci. 2012 Dec 5; 32(49):17800-12.
    View in: PubMed
  4. Talos DM, Chang M, Kosaras B, Fitzgerald E, Murphy A, Folkerth RD, Jensen FE. Antiepileptic effects of levetiracetam in a rodent neonatal seizure model. Pediatr Res. 2013 Jan; 73(1):24-30.
    View in: PubMed
  5. Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM. Finding a better drug for epilepsy: antiepileptogenesis targets. Epilepsia. 2012 Nov; 53(11):1868-76.
    View in: PubMed
  6. Talos DM, Sun H, Zhou X, Fitzgerald EC, Jackson MC, Klein PM, Lan VJ, Joseph A, Jensen FE. The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway. PLoS One. 2012; 7(5):e35885.
    View in: PubMed
  7. Talos DM, Sun H, Kosaras B, Joseph A, Folkerth RD, Poduri A, Madsen JR, Black PM, Jensen FE. Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. Ann Neurol. 2012 Apr; 71(4):539-51.
    View in: PubMed
  8. Selip DB, Jantzie LL, Chang M, Jackson MC, Fitzgerald EC, Boll G, Murphy A, Jensen FE. Regional differences in susceptibility to hypoxic-ischemic injury in the preterm brain: exploring the spectrum from white matter loss to selective grey matter injury in a rat model. Neurol Res Int. 2012; 2012:725184.
    View in: PubMed
  9. Kabakov AY, Muller PA, Pascual-Leone A, Jensen FE, Rotenberg A. Contribution of axonal orientation to pathway-dependent modulation of excitatory transmission by direct current stimulation in isolated rat hippocampus. J Neurophysiol. 2012 Apr; 107(7):1881-9.
    View in: PubMed
  10. Zhou C, Lippman JJ, Sun H, Jensen FE. Hypoxia-induced neonatal seizures diminish silent synapses and long-term potentiation in hippocampal CA1 neurons. J Neurosci. 2011 Dec 14; 31(50):18211-22.
    View in: PubMed
  11. Jantzie LL, Talos DM, Selip DB, An L, Jackson MC, Folkerth RD, Deng W, Jensen FE. Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia. Neuron Glia Biol. 2010 Nov; 6(4):277-88.
    View in: PubMed
  12. Goto J, Talos DM, Klein P, Qin W, Chekaluk YI, Anderl S, Malinowska IA, Di Nardo A, Bronson RT, Chan JA, Vinters HV, Kernie SG, Jensen FE, Sahin M, Kwiatkowski DJ. Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex. Proc Natl Acad Sci U S A. 2011 Nov 8; 108(45):E1070-9.
    View in: PubMed
  13. Hsieh TH, Dhamne SC, Chen JJ, Pascual-Leone A, Jensen FE, Rotenberg A. A new measure of cortical inhibition by mechanomyography and paired-pulse transcranial magnetic stimulation in unanesthetized rats. J Neurophysiol. 2012 Feb; 107(3):966-72.
    View in: PubMed
  14. Dean JM, Moravec MD, Grafe M, Abend N, Ren J, Gong X, Volpe JJ, Jensen FE, Hohimer AR, Back SA. Strain-specific differences in perinatal rodent oligodendrocyte lineage progression and its correlation with human. Dev Neurosci. 2011; 33(3-4):251-60.
    View in: PubMed
  15. Sarco DP, Boyer K, Lundy-Krigbaum SM, Takeoka M, Jensen F, Gregas M, Waber DP. Benign rolandic epileptiform discharges are associated with mood and behavior problems. Epilepsy Behav. 2011 Oct; 22(2):298-303.
    View in: PubMed
  16. Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA. Reprint of "The developing oligodendrocyte: key cellular target in brain injury in the premature infant". Int J Dev Neurosci. 2011 Oct; 29(6):565-82.
    View in: PubMed
  17. Manning SM, Boll G, Fitzgerald E, Selip DB, Volpe JJ, Jensen FE. The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain. Int J Dev Neurosci. 2011 Nov; 29(7):767-73.
    View in: PubMed
  18. Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA. The developing oligodendrocyte: key cellular target in brain injury in the premature infant. Int J Dev Neurosci. 2011 Jun; 29(4):423-40.
    View in: PubMed
  19. Rakhade SN, Klein PM, Huynh T, Hilario-Gomez C, Kosaras B, Rotenberg A, Jensen FE. Development of later life spontaneous seizures in a rodent model of hypoxia-induced neonatal seizures. Epilepsia. 2011 Apr; 52(4):753-65.
    View in: PubMed
  20. Li Y, Cleary R, Kellogg M, Soul JS, Berry GT, Jensen FE. Sensitive isotope dilution liquid chromatography/tandem mass spectrometry method for quantitative analysis of bumetanide in serum and brain tissue. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Apr 15; 879(13-14):998-1002.
    View in: PubMed
  21. Jensen FE. Epilepsy as a spectrum disorder: Implications from novel clinical and basic neuroscience. Epilepsia. 2011 Jan; 52 Suppl 1:1-6.
    View in: PubMed
  22. Baram TZ, Jensen FE, Brooks-Kayal A. Does acquired epileptogenesis in the immature brain require neuronal death. Epilepsy Curr. 2011 Jan; 11(1):21-6.
    View in: PubMed
  23. Vahabzadeh-Hagh AM, Muller PA, Pascual-Leone A, Jensen FE, Rotenberg A. Measures of cortical inhibition by paired-pulse transcranial magnetic stimulation in anesthetized rats. J Neurophysiol. 2011 Feb; 105(2):615-24.
    View in: PubMed
  24. Sucher NJ, Yu E, Chan SF, Miri M, Lee BJ, Xiao B, Worley PF, Jensen FE. Association of the small GTPase Rheb with the NMDA receptor subunit NR3A. Neurosignals. 2010; 18(4):203-9.
    View in: PubMed
  25. Jensen FE. Neonatal seizures: an update on mechanisms and management. Clin Perinatol. 2009 Dec; 36(4):881-900, vii.
    View in: PubMed
  26. Rotenberg A, Muller PA, Vahabzadeh-Hagh AM, Navarro X, López-Vales R, Pascual-Leone A, Jensen F. Lateralization of forelimb motor evoked potentials by transcranial magnetic stimulation in rats. Clin Neurophysiol. 2010 Jan; 121(1):104-8.
    View in: PubMed
  27. Jensen FE. Introduction--epileptogenic cortical dysplasia: emerging trends in diagnosis, treatment, and pathogenesis. Epilepsia. 2009 Oct; 50 Suppl 9:1-2.
    View in: PubMed
  28. Zhou C, Jensen FE, Sucher NJ. Altered development of glutamatergic synapses in layer V pyramidal neurons in NR3A knockout mice. Mol Cell Neurosci. 2009 Dec; 42(4):419-26.
    View in: PubMed
  29. Rakhade SN, Jensen FE. Epileptogenesis in the immature brain: emerging mechanisms. Nat Rev Neurol. 2009 Jul; 5(7):380-91.
    View in: PubMed
  30. Gerstner B, Lee J, DeSilva TM, Jensen FE, Volpe JJ, Rosenberg PA. 17beta-estradiol protects against hypoxic/ischemic white matter damage in the neonatal rat brain. J Neurosci Res. 2009 Jul; 87(9):2078-86.
    View in: PubMed
  31. Jacobs MP, Leblanc GG, Brooks-Kayal A, Jensen FE, Lowenstein DH, Noebels JL, Spencer DD, Swann JW. Curing epilepsy: progress and future directions. Epilepsy Behav. 2009 Mar; 14(3):438-45.
    View in: PubMed
  32. Aujla PK, Fetell MR, Jensen FE. Talampanel suppresses the acute and chronic effects of seizures in a rodent neonatal seizure model. Epilepsia. 2009 Apr; 50(4):694-701.
    View in: PubMed
  33. Jensen FE. Introduction. Posttraumatic epilepsy: treatable epileptogenesis. Epilepsia. 2009 Feb; 50 Suppl 2:1-3.
    View in: PubMed
  34. Rotenberg A, Muller P, Birnbaum D, Harrington M, Riviello JJ, Pascual-Leone A, Jensen FE. Seizure suppression by EEG-guided repetitive transcranial magnetic stimulation in the rat. Clin Neurophysiol. 2008 Dec; 119(12):2697-702.
    View in: PubMed
  35. Rakhade SN, Zhou C, Aujla PK, Fishman R, Sucher NJ, Jensen FE. Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures. J Neurosci. 2008 Aug 6; 28(32):7979-90.
    View in: PubMed
  36. Silverstein FS, Jensen FE, Inder T, Hellstrom-Westas L, Hirtz D, Ferriero DM. Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop report. J Pediatr. 2008 Jul; 153(1):12-5.
    View in: PubMed
  37. Manning SM, Talos DM, Zhou C, Selip DB, Park HK, Park CJ, Volpe JJ, Jensen FE. NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia. J Neurosci. 2008 Jun 25; 28(26):6670-8.
    View in: PubMed
  38. Talos DM, Kwiatkowski DJ, Cordero K, Black PM, Jensen FE. Cell-specific alterations of glutamate receptor expression in tuberous sclerosis complex cortical tubers. Ann Neurol. 2008 Apr; 63(4):454-65.
    View in: PubMed
  39. Lechpammer M, Manning SM, Samonte F, Nelligan J, Sabo E, Talos DM, Volpe JJ, Jensen FE. Minocycline treatment following hypoxic/ischaemic injury attenuates white matter injury in a rodent model of periventricular leucomalacia. Neuropathol Appl Neurobiol. 2008 Aug; 34(4):379-93.
    View in: PubMed
  40. Rotenberg A, Harrington MG, Birnbaum DS, Madsen JR, Glass IE, Jensen FE, Pascual-Leone A. Minimal heating of titanium skull plates during 1Hz repetitive transcranial magnetic stimulation. Clin Neurophysiol. 2007 Nov; 118(11):2536-8.
    View in: PubMed
  41. Silverstein FS, Jensen FE. Neonatal seizures. Ann Neurol. 2007 Aug; 62(2):112-20.
    View in: PubMed
  42. Meikle L, Talos DM, Onda H, Pollizzi K, Rotenberg A, Sahin M, Jensen FE, Kwiatkowski DJ. A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. J Neurosci. 2007 May 23; 27(21):5546-58.
    View in: PubMed
  43. Jensen FE. Developmental factors regulating susceptibility to perinatal brain injury and seizures. Curr Opin Pediatr. 2006 Dec; 18(6):628-33.
    View in: PubMed
  44. Jensen FE, Bourgeois BF. Randomized trial supports use of levetiracetam adjunctive therapy to treat partial seizures in children. Nat Clin Pract Neurol. 2006 Nov; 2(11):596-7.
    View in: PubMed
  45. Deng W, Neve RL, Rosenberg PA, Volpe JJ, Jensen FE. Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit composition and cAMP-response element-binding protein regulate oligodendrocyte excitotoxicity. J Biol Chem. 2006 Nov 24; 281(47):36004-11.
    View in: PubMed
  46. Talos DM, Follett PL, Folkerth RD, Fishman RE, Trachtenberg FL, Volpe JJ, Jensen FE. Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. II. Human cerebral white matter and cortex. J Comp Neurol. 2006 Jul 1; 497(1):61-77.
    View in: PubMed
  47. Talos DM, Fishman RE, Park H, Folkerth RD, Follett PL, Volpe JJ, Jensen FE. Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. I. Rodent cerebral white matter and cortex. J Comp Neurol. 2006 Jul 1; 497(1):42-60.
    View in: PubMed
  48. Deng W, Yue Q, Rosenberg PA, Volpe JJ, Jensen FE. Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function. J Neurochem. 2006 Jul; 98(1):213-22.
    View in: PubMed
  49. Jensen FE. Pediatric epilepsy models. Epilepsy Res. 2006 Jan; 68(1):28-31.
    View in: PubMed
  50. Jensen FE. Role of glutamate receptors in periventricular leukomalacia. J Child Neurol. 2005 Dec; 20(12):950-9.
    View in: PubMed
  51. Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ. NKCC1 transporter facilitates seizures in the developing brain. Nat Med. 2005 Nov; 11(11):1205-13.
    View in: PubMed
  52. Sanchez RM, Dai W, Levada RE, Lippman JJ, Jensen FE. AMPA/kainate receptor-mediated downregulation of GABAergic synaptic transmission by calcineurin after seizures in the developing rat brain. J Neurosci. 2005 Mar 30; 25(13):3442-51.
    View in: PubMed
  53. Wang H, Li J, Follett PL, Zhang Y, Cotanche DA, Jensen FE, Volpe JJ, Rosenberg PA. 12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes. Eur J Neurosci. 2004 Oct; 20(8):2049-58.
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  54. Koh S, Tibayan FD, Simpson JN, Jensen FE. NBQX or topiramate treatment after perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury. Epilepsia. 2004 Jun; 45(6):569-75.
    View in: PubMed
  55. Deng W, Wang H, Rosenberg PA, Volpe JJ, Jensen FE. Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7751-6.
    View in: PubMed
  56. Follett PL, Deng W, Dai W, Talos DM, Massillon LJ, Rosenberg PA, Volpe JJ, Jensen FE. Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. J Neurosci. 2004 May 5; 24(18):4412-20.
    View in: PubMed
  57. Lehnardt S, Massillon L, Follett P, Jensen FE, Ratan R, Rosenberg PA, Volpe JJ, Vartanian T. Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. Proc Natl Acad Sci U S A. 2003 Jul 8; 100(14):8514-9.
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  58. Deng W, Rosenberg PA, Volpe JJ, Jensen FE. Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6801-6.
    View in: PubMed
  59. Rosenberg PA, Dai W, Gan XD, Ali S, Fu J, Back SA, Sanchez RM, Segal MM, Follett PL, Jensen FE, Volpe JJ. Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicity. J Neurosci Res. 2003 Jan 15; 71(2):237-45.
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  60. Jensen FE. The role of glutamate receptor maturation in perinatal seizures and brain injury. Int J Dev Neurosci. 2002 Jun-Aug; 20(3-5):339-47.
    View in: PubMed
  61. Lehnardt S, Lachance C, Patrizi S, Lefebvre S, Follett PL, Jensen FE, Rosenberg PA, Volpe JJ, Vartanian T. The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS. J Neurosci. 2002 Apr 1; 22(7):2478-86.
    View in: PubMed
  62. Jensen FE. Relationship between encephalopathy and abnormal neuronal activity in the developing brain. Int Rev Neurobiol. 2002; 49:23-35.
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  63. Sanchez RM, Koh S, Rio C, Wang C, Lamperti ED, Sharma D, Corfas G, Jensen FE. Decreased glutamate receptor 2 expression and enhanced epileptogenesis in immature rat hippocampus after perinatal hypoxia-induced seizures. J Neurosci. 2001 Oct 15; 21(20):8154-63.
    View in: PubMed
  64. Koh S, Jensen FE. Topiramate blocks perinatal hypoxia-induced seizures in rat pups. Ann Neurol. 2001 Sep; 50(3):366-72.
    View in: PubMed
  65. Sanchez RM, Jensen FE. Maturational aspects of epilepsy mechanisms and consequences for the immature brain. Epilepsia. 2001 May; 42(5):577-85.
    View in: PubMed
  66. Follett PL, Rosenberg PA, Volpe JJ, Jensen FE. NBQX attenuates excitotoxic injury in developing white matter. J Neurosci. 2000 Dec 15; 20(24):9235-41.
    View in: PubMed
  67. Sanchez RM, Wang C, Gardner G, Orlando L, Tauck DL, Rosenberg PA, Aizenman E, Jensen FE. Novel role for the NMDA receptor redox modulatory site in the pathophysiology of seizures. J Neurosci. 2000 Mar 15; 20(6):2409-17.
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  68. Jensen FE, Baram TZ. Developmental seizures induced by common early-life insults: short- and long-term effects on seizure susceptibility. Ment Retard Dev Disabil Res Rev. 2000; 6(4):253-7.
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  69. Holtzman D, Khait I, Mulkern R, Allred E, Rand T, Jensen F, Kraft R. In vivo development of brain phosphocreatine in normal and creatine-treated rabbit pups. J Neurochem. 1999 Dec; 73(6):2477-84.
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  70. Stafstrom CE, Wang C, Jensen FE. Electrophysiological observations in hippocampal slices from rats treated with the ketogenic diet. Dev Neurosci. 1999 Nov; 21(3-5):393-9.
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  71. Jensen FE. Acute and chronic effects of seizures in the developing brain: experimental models. Epilepsia. 1999; 40 Suppl 1:S51-8; discussion S64-6.
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  72. Chen HS, Wang YF, Rayudu PV, Edgecomb P, Neill JC, Segal MM, Lipton SA, Jensen FE. Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation. Neuroscience. 1998 Oct; 86(4):1121-32.
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  73. Holtzman D, Togliatti A, Khait I, Jensen F. Creatine increases survival and suppresses seizures in the hypoxic immature rat. Pediatr Res. 1998 Sep; 44(3):410-4.
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  74. Holtzman D, Mulkern R, Meyers R, Cook C, Allred E, Khait I, Jensen F, Tsuji M, Laussen P. In vivo phosphocreatine and ATP in piglet cerebral gray and white matter during seizures. Brain Res. 1998 Feb 2; 783(1):19-27.
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  75. Jensen FE, Wang C, Stafstrom CE, Liu Z, Geary C, Stevens MC. Acute and chronic increases in excitability in rat hippocampal slices after perinatal hypoxia In vivo. J Neurophysiol. 1998 Jan; 79(1):73-81.
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  76. Holtzman D, Meyers R, O'Gorman E, Khait I, Wallimann T, Allred E, Jensen F. In vivo brain phosphocreatine and ATP regulation in mice fed a creatine analog. Am J Physiol. 1997 May; 272(5 Pt 1):C1567-77.
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  77. Holtzman D, Meyers R, Khait I, Jensen F. Brain creatine kinase reaction rates and reactant concentrations during seizures in developing rats. Epilepsy Res. 1997 Apr; 27(1):7-11.
    View in: PubMed
  78. Jensen FE, Wang C. Hypoxia-induced hyperexcitability in vivo and in vitro in the immature hippocampus. Epilepsy Res. 1996 Dec; 26(1):131-40.
    View in: PubMed
  79. Applegate CD, Jensen F, Burchfiel JL, Lombroso C. The effects of neonatal hypoxia on kindled seizure development and electroconvulsive shock profiles. Epilepsia. 1996 Aug; 37(8):723-7.
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  80. Wang C, Jensen FE. Age dependence of NMDA receptor involvement in epileptiform activity in rat hippocampal slices. Epilepsy Res. 1996 Mar; 23(2):105-13.
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  81. Jensen FE, Blume H, Alvarado S, Firkusny I, Geary C. NBQX blocks acute and late epileptogenic effects of perinatal hypoxia. Epilepsia. 1995 Oct; 36(10):966-72.
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  82. Tsuji M, Allred E, Jensen F, Holtzman D. Phosphocreatine and ATP regulation in the hypoxic developing rat brain. Brain Res Dev Brain Res. 1995 Apr 18; 85(2):192-200.
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  83. Perides G, Jensen FE, Edgecomb P, Rueger DC, Charness ME. Neuroprotective effect of human osteogenic protein-1 in a rat model of cerebral hypoxia/ischemia. Neurosci Lett. 1995 Feb 24; 187(1):21-4.
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  84. Jensen FE. An animal model of hypoxia-induced perinatal seizures. Ital J Neurol Sci. 1995 Feb-Mar; 16(1-2):59-68.
    View in: PubMed
  85. Jensen FE, Gardner GJ, Williams AP, Gallop PM, Aizenman E, Rosenberg PA. The putative essential nutrient pyrroloquinoline quinone is neuroprotective in a rodent model of hypoxic/ischemic brain injury. Neuroscience. 1994 Sep; 62(2):399-406.
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  86. Thurber SJ, Mikati MA, Stafstrom CE, Jensen FE, Holmes GL. Quisqualic acid-induced seizures during development: a behavioral and EEG study. Epilepsia. 1994 Jul-Aug; 35(4):868-75.
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  87. Aizenman E, Jensen FE, Gallop PM, Rosenberg PA, Tang LH. Further evidence that pyrroloquinoline quinone interacts with the N-methyl-D-aspartate receptor redox site in rat cortical neurons in vitro. Neurosci Lett. 1994 Feb 28; 168(1-2):189-92.
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  88. Jensen F, Tsuji M, Offutt M, Firkusny I, Holtzman D. Profound, reversible energy loss in the hypoxic immature rat brain. Brain Res Dev Brain Res. 1993 May 21; 73(1):99-105.
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  89. Jensen FE, Firkusny IR, Mower GD. Differences in c-fos immunoreactivity due to age and mode of seizure induction. Brain Res Mol Brain Res. 1993 Mar; 17(3-4):185-93.
    View in: PubMed
  90. Chen HS, Pellegrini JW, Aggarwal SK, Lei SZ, Warach S, Jensen FE, Lipton SA. Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci. 1992 Nov; 12(11):4427-36.
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  91. Jensen FE, Holmes GL, Lombroso CT, Blume HK, Firkusny IR. Age-dependent changes in long-term seizure susceptibility and behavior after hypoxia in rats. Epilepsia. 1992 Nov-Dec; 33(6):971-80.
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  92. Harris KM, Jensen FE, Tsao B. Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation. J Neurosci. 1992 Jul; 12(7):2685-705.
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  93. Jensen FE, Applegate CD, Holtzman D, Belin TR, Burchfiel JL. Epileptogenic effect of hypoxia in the immature rodent brain. Ann Neurol. 1991 Jun; 29(6):629-37.
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  94. Jensen FE. Rapid microwave enhanced fixation of brain tissue for electron microscopy. Eur J Morphol. 1991; 29(3):210-2.
    View in: PubMed
  95. Jensen FE, Applegate C, Burchfiel J, Lombroso CT. Differential effects of perinatal hypoxia and anoxia on long term seizure susceptibility in the rat. Life Sci. 1991; 49(5):399-407.
    View in: PubMed
  96. Jensen FE, Harris KM. Preservation of neuronal ultrastructure in hippocampal slices using rapid microwave-enhanced fixation. J Neurosci Methods. 1989 Sep; 29(3):217-30.
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  97. Duffy FH, Jensen F, Erba G, Burchfiel JL, Lombroso CT. Extraction of clinical information from electroencephalographic background activity: the combined use of brain electrical activity mapping and intravenous sodium thiopental. Ann Neurol. 1984 Jan; 15(1):22-30.
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  98. Spinelli DN, Jensen FE, Viana Di Prisco G. Early experience effect on dendritic branching in normally reared kittens. Exp Neurol. 1980 Apr; 68(1):1-11.
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  99. Lenaghan D, Whitaker JG, Jensen F, Stephens FD. The natural history of reflux and long-term effects of reflux on the kidney. J Urol. 1976 Jun; 115(6):728-30.
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